A. Hakansson

Emma M. Rath, R. Knott, W. B. Church, 2015, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.

Multimeric alpha-lactalbumin from human milk induces apoptosis through a direct effect on cell nuclei.

B. Zhivotovsky, S. Orrenius, A. Hakansson, 1999, Experimental cell research.

HAMLET, a Protein Complex from Human Milk, Has Bactericidal Activity and Enhances the Activity of Antibiotics against Pathogenic Streptococci

K. Riesbeck, A. Hakansson, Feiruz Alamiri, 2019, Antimicrobial Agents and Chemotherapy.

Extracellular group A Streptococcus induces keratinocyte apoptosis by dysregulating calcium signalling

M. Wessels, A. Hakansson, Colette Cywes Bentley, 2005, Cellular microbiology.

Capsule Independent Antimicrobial Activity Induced by Nanochitosan against Streptococcus pneumoniae

A. Hakansson, F. Alqahtani, F. Aleanizy, 2021, Polymers.

Halothane Modulates the Type I Interferon Response to Influenza and Minimizes the Risk of Secondary Bacterial Pneumonia through Maintenance of Neutrophil Recruitment in an Animal Model

K. Chakravarthy, A. Hakansson, B. Davidson, 2015, Anesthesiology.

Mg2+ signalling defines the group A streptococcal CsrRS (CovRS) regulon

G. Grandi, M. Wessels, Shengmei Jiang, 2007, Molecular microbiology.

Streptococcus pyogenes biofilm growth in vitro and in vivo and its role in colonization, virulence, and genetic exchange.

M. Federle, L. Mashburn-Warren, A. Hakansson, 2014, The Journal of infectious diseases.

Dynamic Changes in the Streptococcus pneumoniae Transcriptome during Transition from Biofilm Formation to Invasive Disease upon Influenza A Virus Infection

Y. Kong, J. Gent, A. Hakansson, 2014, Infection and Immunity.

Monitoring changes in membrane polarity, membrane integrity, and intracellular ion concentrations in Streptococcus pneumoniae using fluorescent dyes.

A. Hakansson, Laura R Marks, E. Clementi, 2014, Journal of visualized experiments : JoVE.

HAMLET a human milk protein‐lipid complex induces a pro‐inflammatory phenotype of myeloid cells

A. Hakansson, C. Bergenfelz, Goutham Vansarla, 2020, European journal of immunology.

Influence of the Polysaccharide Capsule on the Bactericidal Activity of Indolicidin on Streptococcus pneumoniae

A. Hakansson, N. Lincopan, R. Girardello, 2022, Frontiers in Microbiology.

Regions of PspA/EF3296 Best Able To Elicit Protection against Streptococcus pneumoniae in a Murine Infection Model

A. Hakansson, D. Briles, S. Hollingshead, 2003, Infection and Immunity.

Absence of capsule reveals glycan-mediated binding and recognition of salivary mucin MUC7 by Streptococcus pneumoniae.

A. Hakansson, H. Roche-Håkansson, S. Ruhl, 2016, Molecular oral microbiology.

Role of Dihydrolipoamide Dehydrogenase in Regulation of Raffinose Transport in Streptococcus pneumoniae

A. Hakansson, R. Tyx, H. Roche-Håkansson, 2011, Journal of bacteriology.

Enzymatic Characterization of Dihydrolipoamide Dehydrogenase from Streptococcus pneumoniae Harboring Its Own Substrate*

A. Hakansson, Alexander W. Smith, 2007, Journal of Biological Chemistry.

Relative Roles of Genetic Background and Variation in PspA in the Ability of Antibodies to PspA To Protect against Capsular Type 3 and 4 Strains of Streptococcus pneumoniae

L. McDaniel, A. Hakansson, D. Briles, 2003, Infection and Immunity.

Characterization of the dihydrolipoamide dehydrogenase from Streptococcus pneumoniae and its role in pneumococcal infection

A. Hakansson, D. Briles, H. Roche, 2002, Molecular microbiology.

Panel 6: Vaccines

A. Hakansson, K. Mason, L. Bakaletz, 2013, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

Pneumococcal Genetic Transformation During Colonization and Biofilm Formation

A. Hakansson, Laura R Marks, H. Roche-Håkansson, 2015 .

Streptolysin O Inhibits Clathrin-Dependent Internalization of Group A Streptococcus

M. Wessels, A. Hakansson, Lauren K. Logsdon, 2011, mBio.

Cytolysin-dependent evasion of lysosomal killing.

M. Wessels, A. Hakansson, Colette Cywes Bentley, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Internalization and Trafficking of Nontypeable Haemophilus influenzae in Human Respiratory Epithelial Cells and Roles of IgA1 Proteases for Optimal Invasion and Persistence

A. Hakansson, T. Murphy, Cara F. Clementi, 2013, Infection and Immunity.

Adenovirus infection enhances in vitro adherence of Streptococcus pneumoniae

A. Hakansson, C. Svanborg, A. Kidd, 1994, Infection and immunity.

Low NF-κB Activation and Necroptosis in Alveolar Macrophages: A New Virulence Property of Streptococcus pneumoniae.

A. Hakansson, C. Bergenfelz, 2017, The Journal of infectious diseases.

Panel 4: Report of the Microbiology Panel

T. Heikkinen, A. Hakansson, J. Patel, 2017, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

A Complex of Equine Lysozyme and Oleic Acid with Bactericidal Activity against Streptococcus pneumoniae

A. Hakansson, J. Schleucher, E. Clementi, 2013, PloS one.

Streptococcus pneumoniae Otitis Media Pathogenesis and How It Informs Our Understanding of Vaccine Strategies

A. Hakansson, C. Bergenfelz, 2017, Current Otorhinolaryngology Reports.

influenzae in human respiratory epithelial cells and the roles of IgA1

A. Hakansson, T. Murphy, Cara F. Clementi, 2013 .

Protective effects of human milk antimicrobial peptides against bacterial infection.

A. Hakansson, 2015, Jornal de pediatria.

Klebsiella pneumoniae Biofilms and Their Role in Disease Pathogenesis

M. E. Guerra, A. Hakansson, T. R. Converso, 2022, Frontiers in Cellular and Infection Microbiology.

The serine protease HtrA plays a key role in heat-induced dispersal of pneumococcal biofilms

A. Hakansson, A. Achour, R. Sun, 2020, Scientific Reports.

Hamlet--a complex from human milk that induces apoptosis in tumor cells but spares healthy cells.

S. Linse, A. Hakansson, C. Svanborg, 2002, Advances in experimental medicine and biology.

Novel Strategy To Protect against Influenza Virus-Induced Pneumococcal Disease without Interfering with Commensal Colonization

Christopher J. Greene, A. Hakansson, T. D. Connell, 2016, Infection and Immunity.

A particulate matter: How environmental irritants and particulate matter increase sensitivity to bacterial respiratory tract infections. Commentary for “Underground railway particulate matter and susceptibility to pneumococcal infection”

A. Hakansson, 2022, EBioMedicine.

A folding variant of human alpha-lactalbumin induces mitochondrial permeability transition in isolated mitochondria.

B. Zhivotovsky, V. Gogvadze, S. Orrenius, 2001, European journal of biochemistry.

Binding of Haemophilus influenzae to purified mucins from the human respiratory tract

A. Hakansson, C. Svanborg, L. van Alphen, 1995, Infection and immunity.

A folding variant of α‐lactalbumin with bactericidal activity against Streptococcus pneumoniae

S. Linse, A. Hakansson, I. Lazou, 2000, Molecular microbiology.

Aspects on the interaction of Streptococcus pneumoniae and Haemophilus influenzae with human respiratory tract mucosa.

A. Hakansson, C. Svanborg, J. Davies, 1996, American journal of respiratory and critical care medicine.

In Vivo Activation of Dendritic Cells and T Cells during Salmonella enterica Serovar Typhimurium Infection

H. Ljunggren, A. Hakansson, M. Svensson, 2001, Infection and Immunity.

Functional Antibodies Against SARS-CoV-2 Receptor Binding Domain Variants with Mutations N501Y or E484K in Human Milk from COVID-19-Vaccinated, -Recovered, and -Unvaccinated Women.

A. Hakansson, Shawn Fels, E. Medo, 2021, Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine.

A folding variant of α‐lactalbumin with bactericidal activity against Streptococcus pneumoniae

S. Linse, A. Hakansson, I. Lazou, 2000 .

A Protein Complex from Human Milk Enhances the Activity of Antibiotics and Drugs against Mycobacterium tuberculosis

M. Niederweis, A. Hakansson, Avishek Mitra, 2018, Antimicrobial Agents and Chemotherapy.

Apoptosis-Like Death in Bacteria Induced by HAMLET, a Human Milk Lipid-Protein Complex

A. Hakansson, C. Svanborg, A. Mossberg, 2011, PloS one.

Niche- and Gender-Dependent Immune Reactions in Relation to the Microbiota Profile in Pediatric Patients with Otitis Media with Effusion

A. Hakansson, D. Bogaert, F. Enoksson, 2020, Infection and Immunity.

The human milk protein-lipid complex HAMLET disrupts glycolysis and induces death in Streptococcus pneumoniae

A. Hakansson, Laura R Marks, H. Roche-Håkansson, 2019, The Journal of Biological Chemistry.

Molecular Characterization of α–Lactalbumin Folding Variants That Induce Apoptosis in Tumor Cells*

S. Linse, A. Hakansson, C. Svanborg, 1999, Journal of Biological Chemistry.

Biomaterials at the interface of nano- and micro-scale vector-cellular interactions in genetic vaccine design.

Charles H Jones, Anders P Hakansson, Blaine A Pfeifer, 2014, Journal of materials chemistry. B.

Mannosylated poly(beta-amino esters) for targeted antigen presenting cell immune modulation.

Charles H Jones, Anders P Hakansson, Blaine A Pfeifer, 2015, Biomaterials.

Apoptosis induced by a human milk protein.

B. Zhivotovsky, S. Orrenius, A. Hakansson, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Pneumococcal adaptive responses to changing host environments.

A. Hakansson, 2014, The Journal of infectious diseases.

A Murine Model for the Transition of Streptococcus pneumoniae from Asymptomatic Colonizer to Systemic Pathogen

S. Roggensack, S. Meydani, A. Hakansson, 2020, bioRxiv.

Enhancement of Streptolysin O Activity and Intrinsic Cytotoxic Effects of the Group A Streptococcal Toxin, NAD-Glycohydrolase*

M. Wessels, A. Hakansson, A. Michos, 2006, Journal of Biological Chemistry.

Apoptosis of Renal Cortical Cells in the Hemolytic-Uremic Syndrome: In Vivo and In Vitro Studies

A. Caprioli, A. Hakansson, C. Svanborg, 1998, Infection and Immunity.

Streptococcus pneumoniae biofilm formation and dispersion during colonization and disease

A. Hakansson, M. Pettigrew, Laura R Marks, 2015, Front. Cell. Infect. Microbiol..

High Levels of Genetic Recombination during Nasopharyngeal Carriage and Biofilm Formation in Streptococcus pneumoniae

A. Hakansson, Laura R Marks, Laura R. Marks, 2012, mBio.

Bacterial-Host Interactions: Physiology and Pathophysiology of Respiratory Infection.

A. Hakansson, C. Orihuela, D. Bogaert, 2018, Physiological reviews.

Conversion of alpha-lactalbumin to a protein inducing apoptosis.

S. Linse, A. Hakansson, C. Svanborg, 2000, Proceedings of the National Academy of Sciences of the United States of America.

A Role of Epithelial Cells and Virulence Factors in Biofilm Formation by Streptococcus pyogenes In Vitro

K. Riesbeck, A. Hakansson, M. Baumgarten, 2020, Infection and Immunity.

Protease activation in apoptosis induced by MAL.

B. Zhivotovsky, S. Orrenius, A. Hakansson, 1999, Experimental cell research.

Streptococcus pneumoniae Modulates Staphylococcus aureus Biofilm Dispersion and the Transition from Colonization to Invasive Disease

Nicole R. Luke-Marshall, A. Hakansson, A. Campagnari, 2018, mBio.

A Novel Initiation Mechanism of Death in Streptococcus pneumoniae Induced by the Human Milk Protein-Lipid Complex HAMLET and Activated during Physiological Death*

A. Hakansson, Laura R Marks, M. Duffey, 2012, The Journal of Biological Chemistry.

BAMLET kills chemotherapy-resistant mesothelioma cells, holding oleic acid in an activated cytotoxic state

Emma M. Rath, R. Knott, G. Reid, 2018, PloS one.

A novel method for preparation of HAMLET-like protein complexes.

E. Permyakov, A. Hakansson, S. Permyakov, 2011, Biochimie.

Host Physiologic Changes Induced by Influenza A Virus Lead to Staphylococcus aureus Biofilm Dispersion and Transition from Asymptomatic Colonization to Invasive Disease

Nicole R. Luke-Marshall, A. Hakansson, A. Campagnari, 2016, mBio.

Oleic acid is a key cytotoxic component of HAMLET-like complexes

E. Permyakov, A. Hakansson, S. Permyakov, 2012, Biological chemistry.

Small‐angle X‐ray scattering of BAMLET at pH 12: A complex of α‐lactalbumin and oleic acid

Emma M. Rath, R. Knott, W. B. Church, 2014, Proteins.

In situ pneumococcal vaccine production and delivery through a hybrid biological-biomaterial vector

Mahmoud Kamal Ahmadi, Lei Fang, S. Andreadis, 2016, Science Advances.

Directed vaccination against pneumococcal disease

A. Hakansson, B. Pfeifer, Charles H. Jones, 2016, Proceedings of the National Academy of Sciences.

Pneumococcal Interactions with Epithelial Cells Are Crucial for Optimal Biofilm Formation and Colonization In Vitro and In Vivo

A. Hakansson, G. Parameswaran, Laura R Marks, 2012, Infection and Immunity.

optimal biofilm formation and colonization in vitro and in vivo.

A. Hakansson, G. Parameswaran, Laura R Marks, 2012 .

In Vitro and In Vivo Biofilm Formation by Pathogenic Streptococci.

A. Hakansson, C. Bergenfelz, Yashuan Chao, 2017, Methods in molecular biology.

The Human Milk Protein-Lipid Complex HAMLET Sensitizes Bacterial Pathogens to Traditional Antimicrobial Agents

A. Hakansson, Laura R. Marks, Emily A. Clementi, 2012, PloS one.

Treatment of Mouse Infants with Amoxicillin, but Not the Human Milk-Derived Antimicrobial HAMLET, Impairs Lung Th17 Responses

A. Hakansson, S. Shekhar, F. Petersen, 2023, Antibiotics.

Growing and Characterizing Biofilms Formed by Streptococcus pneumoniae.

A. Hakansson, C. Bergenfelz, Yashuan Chao, 2019, Methods in molecular biology.

Role of serotype and virulence determinants of Streptococcus pyogenes biofilm bacteria in internalization and persistence in epithelial cells in vitro

A. Hakansson, Oscar André, Feiruz Alamiri, 2023, Frontiers in Cellular and Infection Microbiology.

DNA fragmentation characteristic of apoptosis and cell loss induced by kainic acid in rabbit retinas

Maria-Thereza R. Perez, A. Hakansson, K. Arnér, 1997, Neurochemistry International.

Aspects on the Interadion of Streptococcus pneumonlae and Haemophilus intfuenzae with Human Respiratory Trad Mucosa

A. Hakansson, C. Svanborg, J. Davies, 1996 .

Biofilm Formation Enhances Fomite Survival of Streptococcus pneumoniae and Streptococcus pyogenes

A. Hakansson, Laura R. Marks, Ryan M. Reddinger, 2013, Infection and Immunity.

Hybrid biosynthetic gene therapy vector development and dual engineering capacity

Mingfu Chen, Blaine A. Pfeifer, Anitha Ravikrishnan, 2014, Proceedings of the National Academy of Sciences.

Apoptosis induced by a human milk protein complex. Cellular and structural studies in tumour cells and bacteria.

A. Hakansson, 1999 .

Hybrid biosynthetic gene therapy vector development and dual engineering capacity

Anitha Ravikrishnan, A. Hakansson, B. Pfeifer, 2014, Proceedings of the National Academy of Sciences.

Mannosylated poly(beta-amino esters) for targeted antigen presenting cell immune modulation.

Anitha Ravikrishnan, A. Hakansson, B. Pfeifer, 2015, Biomaterials.

Conversion of a-lactalbumin to a protein inducing apoptosis

S. Linse, A. Hakansson, C. Svanborg, 2000 .

Antibodies to pneumococcal polysaccharides in human milk: lack of relationship to colonization and acute otitis media.

A. Hakansson, C. Svanborg, O. Nylén, 1996, The Pediatric infectious disease journal.