J. An

发表

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance.

Svati H Shah, L. Svetkey, O. Ilkayeva, 2009, Cell metabolism.

The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase.

D. Chuang, O. Ilkayeva, C. Newgard, 2018, Cell metabolism.

Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export

O. Ilkayeva, M. Brosnan, J. Trimmer, 2016, Molecular metabolism.

Obesity and lipid stress inhibit carnitine acetyltransferase activity[S]

O. Ilkayeva, C. Newgard, D. Muoio, 2014, Journal of Lipid Research.

Metabolic Mechanisms of Muscle Insulin Resistance

C. Newgard, D. Muoio, J. An, 2008 .

Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2

J. An, Q. Tong, Cheng Wang, 2019, Nature Communications.

Overexpression of Rat Long Chain Acyl-CoA Synthetase 1 Alters Fatty Acid Metabolism in Rat Primary Hepatocytes*

R. Coleman, C. Newgard, D. Mashek, 2006, Journal of Biological Chemistry.

Hepatic Overexpression of Glycerol-sn-3-phosphate Acyltransferase 1 in Rats Causes Insulin Resistance*

Shuli Wang, R. Coleman, G. Shulman, 2007, Journal of Biological Chemistry.

A VGF-derived peptide attenuates development of type 2 diabetes via enhancement of islet β-cell survival and function.

C. Newgard, J. Schisler, J. An, 2012, Cell metabolism.

Physiological mechanisms of sustained fumagillin-induced weight loss.

T. Hughes, J. Gordon, O. Ilkayeva, 2018, JCI insight.

Overexpression of a Modified Human Malonyl-CoA Decarboxylase Blocks the Glucose-induced Increase in Malonyl-CoA Level but Has No Impact on Insulin Secretion in INS-1-derived (832/13) β-Cells*

H. Mulder, C. Newgard, Danhong Lu, 2001, The Journal of Biological Chemistry.

Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability

O. Ilkayeva, C. Newgard, J. Rathmell, 2011, Molecular biology of the cell.

Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance

David Millington, G. Shulman, G. Cline, 2004, Nature Medicine.

Peroxisome Proliferator-activated Receptor-γ Co-activator 1α-mediated Metabolic Remodeling of Skeletal Myocytes Mimics Exercise Training and Reverses Lipid-induced Mitochondrial Inefficiency*

Ping Li, Olga Ilkayeva, O. Ilkayeva, 2005, Journal of Biological Chemistry.

Absence of the SRC-2 Coactivator Results in a Glycogenopathy Resembling Von Gierke's Disease

P. Saha, B. O’Malley, D. Moore, 2008, Science.

Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine Depletion.

Scott B. Crown, W. Kraus, O. Ilkayeva, 2020, Cell reports.

Adenovirus‐Mediated Leptin Expression Normalises Hypertension Associated with Diet‐Induced Obesity

C. Newgard, J. An, W. Zhang, 2010, Journal of neuroendocrinology.

Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2

J. An, Q. Tong, Cheng Wang, 2019, Nature Communications.

WW domain-binding protein 2 overexpression prevents diet-induced liver steatosis and insulin resistance through AMPKβ1

Kai Huang, J. An, Yue Li, 2021, Cell Death & Disease.

The coactivator SRC-1 is an essential coordinator of hepatic glucose production.

P. Saha, B. O’Malley, Jianming Xu, 2010, Cell metabolism.

Loss of CHIP Expression Perturbs Glucose Homeostasis and Leads to Type II Diabetes through Defects in Microtubule Polymerization and Glucose Transporter Localization

C. Newgard, J. Schisler, Holly McDonough, 2016, bioRxiv.

Improving human β-cell maturation in vitro

C. Newgard, J. An, H. Hohmeier, 2019, Nature Cell Biology.