H. Brunengraber

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Parenteral and enteral metabolism of anaplerotic triheptanoin in normal rats . II . Effects on lipolysis , glucose production , and liver acyl-CoA profile

Guo-Fang Zhang, L. Gu, R. Kombu, 2010 .

Reversibility of the mitochondrial isocitrate dehydrogenase reaction in the perfused rat liver. Evidence from isotopomer analysis of citric acid cycle intermediates.

H. Brunengraber, C. Des Rosiers, C. A. Fernandez, 1994, The Journal of biological chemistry.

Isotopomer Analysis of Citric Acid Cycle and Gluconeogenesis in Rat Liver

H. Brunengraber, C. A. Fernandez, F. David, 1995, The Journal of Biological Chemistry.

Pyruvate carboxylase deficiency: clinical and biochemical response to anaplerotic diet therapy.

F. Mochel, D. Rabier, C. Roe, 2005, Molecular genetics and metabolism.

Correction of 13C mass isotopomer distributions for natural stable isotope abundance.

H. Brunengraber, C. Des Rosiers, C. A. Fernandez, 1996, Journal of mass spectrometry : JMS.

Hyperoxia induces glutamine-fuelled anaplerosis in retinal Müller cells

A. Yuan, H. Brunengraber, J. Sears, 2020, Nature Communications.

Serine and 1-carbon metabolism are required for HIF-mediated protection against retinopathy of prematurity.

Henri Brunengraber, H. Brunengraber, Amit Sharma, 2019, JCI insight.

The urea cycle is transcriptionally controlled by hypoxia-inducible factors

H. Brunengraber, J. Sears, B. Anand-Apte, 2021, bioRxiv.

Glutathione species and metabolomic prints in subjects with liver disease as biological markers for the detection of hepatocellular carcinoma

J. Sanabria, Guo-Fang Zhang, R. Kombu, 2016, HPB : the official journal of the International Hepato Pancreato Biliary Association.

Glycerol production and utilization in humans: sites and quantitation.

J. Wahren, B. Landau, V. Chandramouli, 1996, The American journal of physiology.

Contributions of liver and kidneys to glycerol production and utilization in the dog.

H. Brunengraber, F. David, S. Previs, 1996, The American journal of physiology.

Limitations of the Mass Isotopomer Distribution Analysis of Glucose to Study Gluconeogenesis

H. Brunengraber, F. David, S. Previs, 1998, The Journal of Biological Chemistry.

Regulation of Malonyl-CoA Concentration and Turnover in the Normal Heart*

H. Brunengraber, C. Des Rosiers, F. David, 2004, Journal of Biological Chemistry.

Pseudoketogenesis in hepatectomized dogs.

C. Cobelli, G. Toffolo, B. Landau, 1990, The American journal of physiology.

Quantifying rates of protein synthesis in humans by use of 2H2O: application to patients with end-stage renal disease.

B. Landau, V. Chandramouli, H. Brunengraber, 2004, American journal of physiology. Endocrinology and metabolism.

Partial IVC Clamping Improves Intraoperative Hemodynamic Parameters in the Rodent Portacaval Anastomosis Model

J. Sanabria, H. Brunengraber, K. Mullen, 2011 .

Partitioning of pyruvate between oxidation and anaplerosis in swine hearts.

H. Brunengraber, C. Des Rosiers, C. Rosiers, 2000, American journal of physiology. Heart and circulatory physiology.

Multiple Mass Isotopomer Tracing of Acetyl-CoA Metabolism in Langendorff-perfused Rat Hearts

Guo-Fang Zhang, H. Brunengraber, V. Anderson, 2015, The Journal of Biological Chemistry.

Differential effects of heptanoate and hexanoate on myocardial citric acid cycle intermediates following ischemia-reperfusion.

M. Chandler, Hazel Huang, H. Brunengraber, 2006, Journal of applied physiology.

reperfusion myocardial citric acid cycle intermediates following Differential effects of heptanoate and hexanoate

M. Chandler, Hazel Huang, H. Brunengraber, 2005 .

Post-Ischemic Treatment with Dipyruvyl-Acetyl-Glycerol Decreases Myocardial Infarct Size in the Pig

H. Brunengraber, A. Panchal, W. Stanley, 2003, Cardiovascular Drugs and Therapy.

Probing the link between citrate and malonyl-CoA in perfused rat hearts.

J. Kelleher, H. Brunengraber, C. Des Rosiers, 2002, American journal of physiology. Heart and circulatory physiology.

Effects of hydroxyurea and benzo(a)pyrene on DNA synthesis in the isolated perfused rat lung

G. Wogan, H. Brunengraber, W. Busby, 1982, Bulletin of environmental contamination and toxicology.

Increased glucose availability sensitizes pancreatic cancer to chemotherapy

Renliang Zhang, C. Tatsuoka, H. Brunengraber, 2022, bioRxiv.

Origin of biliary cholesterol and lecithin in the rat: contribution of new synthesis and preformed hepatic stores.

S. Robins, H. Brunengraber, 1982, Journal of lipid research.

New secondary metabolites of phenylbutyrate in humans and rats.

D. Kerr, S. Wehrli, H. Brunengraber, 2004, Drug metabolism and disposition: the biological fate of chemicals.

Identification of phenylbutyrylglutamine, a new metabolite of phenylbutyrate metabolism in humans.

D. Kerr, H. Brunengraber, B. Comte, 2002, Journal of mass spectrometry : JMS.

Glutamate, a window on liver intermediary metabolism.

H. Brunengraber, D. Yang, Dawei Yang, 2000, The Journal of nutrition.

Glutamate and Glutamine in Metabolism Glutamate , a Window on Liver Intermediary Metabolism 1 , 2

H. Brunengraber, Dawei Yang, 2000 .

A probing dose of phenylacetate does not affect glucose production and gluconeogenesis in humans.

B. Landau, V. Chandramouli, H. Brunengraber, 2000, Metabolism: clinical and experimental.

Limitations in estimating gluconeogenesis and Cori cycling from mass isotopomer distributions using [U-13C6]glucose.

J. Wahren, B. Landau, H. Brunengraber, 1998, The American journal of physiology.

Limitations in estimating gluconeogenesis and Cori cycling from mass isotopomer distributions using [U-13C6]glucose.

J. Wahren, B. Landau, H. Brunengraber, 1998, American journal of physiology. Endocrinology and metabolism.

Non-invasive tracing of liver intermediary metabolism in normal subjects and in moderately hyperglycaemic NIDDM subjects. Evidence against increased gluconeogenesis and hepatic fatty acid oxidation in NIDDM

V. Large, M. Beylot, F. Diraison, 1998, Diabetologia.

Limitations of the Mass Isotopomer Distribution Analysis of Glucose to Study Gluconeogenesis

H. Brunengraber, C. A. Fernandez, F. David, 1995, The Journal of Biological Chemistry.

Tracing Hepatic Gluconeogenesis Relative to Citric Acid Cycle Activity in Vitro and in Vivo

M. Beylot, B. Landau, H. Brunengraber, 1995, The Journal of Biological Chemistry.

Determination of (13C) urea enrichment by gas chromatography/mass spectrometry and gas chromatography/isotope ratio mass spectrometry.

V. Large, M. Beylot, H. Brunengraber, 1994, Biological mass spectrometry.

Validation of the Use of Urinary Phenylacetyl-Glutamine to Assess the Labeling Pattern of Liver Citric Acid Cycle Intermediates in Monkeys

H. Brunengraber, C. A. Fernandez, F. David, 1994 .

Shunt pathway of mevalonate metabolism.

B. Landau, H. Brunengraber, 1985, Methods in enzymology.

Compartmentation of 14CO2 in the perfused rat liver.

Stéphane Huot, H. Brunengraber, F. David, 1987, Journal of Biological Chemistry.

Reassessment of 14CO2 compartmentation and of [14C]formate oxidation in rat liver.

H. Brunengraber, F. David, S. Dodgson, 1989, The Journal of biological chemistry.

Determination of the 13C-labeling pattern of glutamate by gas chromatography-mass spectrometry.

M. Beylot, H. Brunengraber, F. David, 1993, Analytical biochemistry.

Determination of the 13C-labeling pattern of glucose by gas chromatography-mass spectrometry.

M. Beylot, H. Brunengraber, F. David, 1993, Analytical biochemistry.

Assay of the deuterium enrichment of water via acetylene.

M. Beylot, F. Diraison, H. Brunengraber, 1996, Journal of mass spectrometry : JMS.

A limitation in the use of mass isotopomer distributions to measure gluconeogenesis in fasting humans.

J. Wahren, B. Landau, V. Chandramouli, 1995, The American journal of physiology.

Composite Vascularized Allograft Machine Preservation: State of the Art

H. Brunengraber, A. Rampazzo, S. Dasarathy, 2019, Current Transplantation Reports.

Pretreatment with Pyridoxamine Mitigates Isolevuglandin-associated Retinal Effects in Mice Exposed to Bright Light*

H. Brunengraber, I. Turko, R. G. Salomon, 2013, The Journal of Biological Chemistry.

Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo

Yiqing Zhao, S. Markowitz, E. Fearon, 2019, Scientific Reports.

Cholesterol in mouse retina originates primarily from in situ de novo biosynthesis

H. Brunengraber, I. Björkhem, I. Pikuleva, 2016, Journal of Lipid Research.

Tenth Annual Meeting of the European Association for the Study of Diabetes

A. J. Honour, W. A. Müller, P. Blackshear, 1974, Diabetologia.

Rates of gluconeogenesis and citric acid cycle in perfused livers, assessed from the mass spectrometric assay of the 13C labeling pattern of glutamate.

H. Brunengraber, C. Des Rosiers, F. David, 1993, The Journal of biological chemistry.

Noninvasive probing of citric acid cycle intermediates in primate liver with phenylacetylglutamine.

M. Beylot, H. Brunengraber, C. A. Fernandez, 1996, The American journal of physiology.

Competition between acetate and oleate for the formation of malonyl-CoA and mitochondrial acetyl-CoA in the perfused rat heart.

C. Hoppel, H. Brunengraber, V. Anderson, 2006, Journal of molecular and cellular cardiology.

Fatty acid and 3- -hydroxysterol synthesis in the perfused rat liver. Including measurements on the production of lactate, pyruvate, -hydroxy-butyrate, and acetoacetate by the fed liver.

J. Lowenstein, H. Brunengraber, M. Boutry, 1973, The Journal of biological chemistry.

Peroxisomal Fatty Acid Oxidation Is a Substantial Source of the Acetyl Moiety of Malonyl-CoA in Rat Heart*

C. Hoppel, H. Brunengraber, C. Des Rosiers, 2004, Journal of Biological Chemistry.

Assay of the concentration and 13C-isotopic enrichment of malonyl-coenzyme A by gas chromatography-mass spectrometry.

H. Brunengraber, C. Des Rosiers, F. David, 2001, Analytical biochemistry.

Assessing the Reversibility of the Anaplerotic Reactions of the Propionyl-CoA Pathway in Heart and Liver*

C. Hoppel, H. Brunengraber, C. Des Rosiers, 2003, Journal of Biological Chemistry.

Assay of the human liver citric acid cycle probe phenylacetylglutamine and of phenylacetate in plasma by gas chromatography-mass spectrometry.

M. Beylot, H. Brunengraber, M. Soloviev, 1993, Analytical biochemistry.

Effect of (−)‐hydroxycitrate on ethanol metabolism

J. Lowenstein, H. Brunengraber, 1973, FEBS letters.

Assay of the concentration and stable isotope enrichment of short-chain fatty acids by gas chromatography/mass spectrometry

M. Beylot, H. Brunengraber, C. L. Kien, 1995 .

Assay of low deuterium enrichment of water by isotopic exchange with [U-13C3]acetone and gas chromatography-mass spectrometry.

M. Samols, M. Beylot, F. Diraison, 1998, Analytical biochemistry.

Tracing gluconeogenesis with deuterated water: measurement of low deuterium enrichments on carbons 6 and 2 of glucose.

H. Brunengraber, F. David, S. Previs, 1997, Analytical biochemistry.

Uptake of artificial model remnant lipoprotein emulsions by the perfused rat liver

A. Tercyak, H. Brunengraber, R. Maranhão, 1988, Lipids.

Labelled Insulin Catabolism and Pancreatic Responsiveness During Long-Term Exercise in Man*

H. Brunengraber, R. Leclercq, J. Franckson, 1971, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Metabolomic and Mass Isotopomer Analysis of Liver Gluconeogenesis and Citric Acid Cycle

J. Kelleher, R. Kombu, H. Brunengraber, 2008, Journal of Biological Chemistry.

In Vitro Modeling of Fatty Acid Synthesis under Conditions Simulating the Zonation of Lipogenic [13C]Acetyl-CoA Enrichment in the Liver*[boxs]

J. Kelleher, H. Brunengraber, F. David, 2004, Journal of Biological Chemistry.

Measurement of rates of lipogenesis with deuterated and tritiated water.

J. Lowenstein, H. Brunengraber, M. Wadke, 1975, Methods in enzymology.

Use of [6,6-2H2]glucose and of low-enrichment [U-13C6]-glucose for sequential or simultaneous measurements of glucose turnover by gas chromatography-mass spectrometry.

M. Beylot, H. Brunengraber, C. A. Fernandez, 1994, Analytical biochemistry.

Zonation of acetate labeling across the liver: implications for studies of lipogenesis by MIDA.

D. Wasserman, H. Brunengraber, F. David, 1999, The American journal of physiology.

Masterclasses in medicine An unusual cause for ketoacidosis

H. Brunengraber, M. Davids, M. Halperin, 2004 .

An unusual cause for ketoacidosis.

H. Brunengraber, M. Davids, M. Halperin, 2004, QJM : monthly journal of the Association of Physicians.

Overcompensation of CoA Trapping by Di(2-ethylhexyl) Phthalate (DEHP) Metabolites in Livers of Wistar Rats

D. Hala, Guo-Fang Zhang, H. Brunengraber, 2021, International journal of molecular sciences.

What is the proper precursor-to-product labeling relationship for calculating the fractional synthetic rate of muscle triglyceride1?

H. Brunengraber, 2012, Journal of Lipid Research.

Fatty Acid, 3‐β‐Hydroxysterol, and Ketone Synthesis in the Perfused Rat Liver

J. Lowenstein, H. Brunengraber, M. Boutry, 1978 .

Contributions by kidney and liver to glucose production in the postabsorptive state and after 60 h of fasting.

J. Wahren, B. Landau, V. Chandramouli, 1999, Diabetes.

Inter-relations between 3-hydroxypropionate and propionate metabolism in rat liver: relevance to disorders of propionyl-CoA metabolism.

G. Cline, Guo-Fang Zhang, H. Brunengraber, 2017, American journal of physiology. Endocrinology and metabolism.

Parenteral and enteral metabolism of anaplerotic triheptanoin in normal rats.

G. Kutz, Wolf-Ulrich Brewer, C. Roe, 2006, American journal of physiology. Endocrinology and metabolism.

Effects of extracellular pH, CO2, and HCO3- on ketogenesis in perfused rat liver.

G. Wu, H. Brunengraber, E. Marliss, 1991, The American journal of physiology.

Fructose as a carbohydrate source yields stable pH and redox parameters in microcarrier cell culture.

W. Thilly, H. Brunengraber, C. Crespi, 1982, Analytical biochemistry.

Microcarrier culture: Applications in biological production and cell biology

W. Thilly, H. Brunengraber, D. Giard, 1981 .

Use of the perfused liver for the study of lipogenesis.

J. Lowenstein, L. Kopelovich, H. Brunengraber, 1975, Methods in enzymology.

on gluconeogenesis and lipolysis in rats Effects of a high-fat diet and voluntary wheel running

Christopher J. Davidson, R. Bergman, T. Zderic, 2015 .

Separation of methyl esters of fatty acids by gas chromatography on capillary columns, including the separation of deuterated from nondeuterated fatty acids.

J. Lowenstein, H. Brunengraber, G. Patton, 1981, Methods in enzymology.

R,S-1,3-butanediol acetoacetate esters, potential alternates to lipid emulsions for total parenteral nutrition

B. Landau, H. Brunengraber, Alok Kumar, 1995 .

The source of acetyl coenzyme A for acetylcholine synthesis in the perfused rat phrenic nerve-hemidiaphragm.

H. Brunengraber, G. Endemann, 1980, The Journal of biological chemistry.

-sensitive neurons in rat brain stem slices + /H 2 COoxygen and chemical oxidants stimulate

C. Piantadosi, A. Moskvin, B. Allen, 2015 .

Rates of catabolism calculated from 14CO2 production: Artifacts and realities

P. Mccaffrey, H. Brunengraber, J. F. Tomera, 1983, Pharmacology Biochemistry and Behavior.

Nonhomogeneous labeling of liver mitochondrial acetyl-CoA.

H. Brunengraber, C. Des Rosiers, F. David, 1991, The Journal of biological chemistry.

Interference of 3-hydroxyisobutyrate with measurements of ketone body concentration and isotopic enrichment by gas chromatography-mass spectrometry.

H. Brunengraber, C. Des Rosiers, F. David, 1988, Analytical biochemistry.

Metabolism of Levulinate in Perfused Rat Livers and Live Rats

S. R. Harris, Guo-Fang Zhang, H. Brunengraber, 2010, The Journal of Biological Chemistry.

Normalization of the α1-Na/K-ATPase/Src Signalosome Restored Microbiota Communities and Rescinded NASH Progression in the Mouse

D. Schlatzer, H. Brunengraber, J. Shapiro, 2021 .

Dipropionylcysteine Ethyl Ester Compensates for Loss of Citric Acid Cycle Intermediates During Post Ischemia Reperfusion in the Pig Heart

Hazel Huang, R. Kombu, H. Brunengraber, 2009, Cardiovascular Drugs and Therapy.

Urinary clearance and metabolism of mevalonate by the isolataed perfused rat kidney.

H. Brunengraber, R. Kopito, D. Story, 1981, Journal of lipid research.

Lactate and pyruvate isotopic enrichments in plasma and tissues of postabsorptive and starved rats.

V. Large, M. Beylot, H. Brunengraber, 1995, The American journal of physiology.

Underestimation of metabolic rates owing to reincorporation of 14CO2 in the perfused rat liver.

W. Rand, H. Brunengraber, J. F. Tomera, 1982, The Biochemical journal.

Metabolism of R- and S-1,3-butanediol in perfused livers from meal-fed and starved rats.

H. Brunengraber, F. David, M. Garneau, 1992, The Biochemical journal.

Assay of the concentration and (13)C isotopic enrichment of propionyl-CoA, methylmalonyl-CoA, and succinyl-CoA by gas chromatography-mass spectrometry.

C. Roe, H. Brunengraber, F. David, 2002, Analytical biochemistry.

Fatty acid synthesis by liver perfused with deuterated and tritiated water.

J. Lowenstein, H. Brunengraber, J. Dolhun, 1973, Biochemistry.

Propionate-induced changes in cardiac metabolism, notably CoA trapping, are not altered by l-carnitine.

Guo-Fang Zhang, D. Muoio, H. Brunengraber, 2018, American journal of physiology. Endocrinology and metabolism.

Compartmentation of Metabolism of the C12-, C9-, and C5-n-dicarboxylates in Rat Liver, Investigated by Mass Isotopomer Analysis

J. Kelleher, Guo-Fang Zhang, H. Brunengraber, 2015, The Journal of Biological Chemistry.

Fatty acid, 3-beta-hydroxysterol, and ketone synthesis in the perfused rat liver. Effects of (--)-hydroxycitrate and oleate.

J. Lowenstein, H. Brunengraber, M. Boutry, 1978, European journal of biochemistry.

Integrative physiology of splanchnic glutamine and ammonium metabolism.

H. Brunengraber, F. David, M. Halperin, 2000, American journal of physiology. Endocrinology and metabolism.

The Dynamics of Glutathione Species and Ophthalmate Concentrations in Plasma from the VX2 Rabbit Model of Secondary Liver Tumors

J. Sanabria, R. Kombu, H. Brunengraber, 2011, HPB surgery : a world journal of hepatic, pancreatic and biliary surgery.

Interrelations between C4 Ketogenesis, C5 Ketogenesis, and Anaplerosis in the Perfused Rat Liver*

Guo-Fang Zhang, C. Roe, H. Brunengraber, 2009, The Journal of Biological Chemistry.

Pseudoketogenesis in the perfused rat heart.

B. Landau, H. Brunengraber, C. Des Rosiers, 1988, The Journal of biological chemistry.

Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats.

H. Brunengraber, M. Puchowicz, C. Ari, 2013, American journal of physiology. Regulatory, integrative and comparative physiology.

Lipogenesis from ketone bodies in the perfused rat liver: effects of acetate and ethanol.

W. Rand, H. Brunengraber, G. Endemann, 1987, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Use of labeling pattern of liver glutamate to calculate rates of citric acid cycle and gluconeogenesis.

V. Large, M. Beylot, H. Brunengraber, 1997, The American journal of physiology.

Metabolomics and mass isotopomer analysis as a strategy for pathway discovery: pyrrolyl and cyclopentenyl derivatives of the pro-drug of abuse, levulinate.

S. R. Harris, Guo-Fang Zhang, H. Brunengraber, 2013, Chemical research in toxicology.

Carnitine palmitoyltransferase II deficiency

C. Roe, H. Brunengraber, D. Roe, 2008, Neurology.

Probing peroxisomal β-oxidation and the labelling of acetyl-CoA proxies with [1-13C]octanoate and [3-13C]octanoate in the perfused rat liver

C. Hoppel, H. Brunengraber, T. Kasumov, 2005 .

Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver.

C. Hoppel, H. Brunengraber, F. David, 2005, The Biochemical journal.

15N enrichment of ammonium, glutamine-amide and urea, measured via mass isotopomer analysis of hexamethylenetetramine.

H. Brunengraber, F. David, M. Halperin, 1999, Journal of mass spectrometry : JMS.

Polyethylene glycol modified-albumin enhances the cold preservation properties of University of Wisconsin solution in rat liver and a hepatocyte cell line.

J. Sanabria, R. Kombu, H. Brunengraber, 2010, The Journal of surgical research.

Dog model of therapeutic ketosis induced by oral administration of R,S-1,3-butanediol diacetoacetate.

H. Brunengraber, F. David, M. Puchowicz, 2000, The Journal of nutritional biochemistry.

Metabolism of (R,S)-1,3-butanediol acetoacetate esters, potential parenteral and enteral nutrients in conscious pigs.

B. Landau, H. Brunengraber, F. David, 1995, The American journal of physiology.

Metabolism of R-beta-hydroxypentanoate and of beta-ketopentanoate in conscious dogs.

H. Brunengraber, C. Des Rosiers, C. A. Fernandez, 1995, The American journal of physiology.

Lipogenesis From Ketone Bodies in Perfused Livers From Streptozocin-Induced Diabetic Rats

H. Brunengraber, L. Freed, V. Gavino, 1988, Diabetes.

Using isotopic tools to dissect and quantitate parallel metabolic pathways.

Guo-Fang Zhang, H. Brunengraber, Gregory P. Tochtrop, 2010, Journal of the American Chemical Society.

Interpretation of isotopomer patterns in tracing glycogen synthesis and glucose recycling using [13C6]glucose.

B. Landau, H. Brunengraber, C. Des Rosiers, 1990, The American journal of physiology.

3- -Hydroxysterol synthesis by the liver.

J. Lowenstein, H. Brunengraber, M. Boutry, 1972, Archives of biochemistry and biophysics.

Catabolism of 4-Hydroxyacids and 4-Hydroxynonenal via 4-Hydroxy-4-phosphoacyl-CoAs*♦

Guo-Fang Zhang, K. Gibson, R. Kombu, 2009, The Journal of Biological Chemistry.

Stable isotope model for assessing production of short chain fatty acids from colon-derived sugar: application in pigs.

R. D. Murray, H. Brunengraber, C. L. Kien, 1996, The Journal of nutrition.

Localization of the pre-squalene segment of the isoprenoid biosynthetic pathway in mammalian peroxisomes

Henri Brunengraber, Xueying Duan, Joanne K. Kelleher, 2007, Histochemistry and Cell Biology.

Production of acetone and conversion of acetone to acetate in the perfused rat liver.

H. Brunengraber, F. David, M. Garneau, 1987, The Journal of biological chemistry.

Metabolism of plasma mevalonate in rats and humans.

H. Brunengraber, L. Freed, R. Kopito, 1982, Journal of lipid research.

Acute hibernation decreases myocardial pyruvate carboxylation and citrate release.

M. Chandler, H. Brunengraber, C. Des Rosiers, 2001, American journal of physiology. Heart and circulatory physiology.

Use of the isolated perfused rat liver to study carcinogen-DNA adduct formation from aflatoxin B1 and sterigmatocystin.

J. Essigmann, G. Wogan, H. Brunengraber, 1980, Cancer research.

Ex-Vivo Normothermic Limb Perfusion With a Hemoglobin-Based Oxygen Carrier Perfusate.

H. Brunengraber, B. B. Gharb, A. Rampazzo, 2020, Military medicine.

Metabolism of S-3-hydroxybutyrate in the perfused rat liver.

H. Brunengraber, C. Des Rosiers, B. Lincoln, 1987, Archives of biochemistry and biophysics.

Investigations by mass isotopomer analysis of the formation of D‐2‐hydroxyglutarate by cultured lymphoblasts from two patients with D‐2‐hydroxyglutaric aciduria

H. Brunengraber, N. Verhoeven, C. Jakobs, 2004, FEBS letters.

Effect of (−)‐hydroxycitrate on ketone production by the perfused liver

J. Lowenstein, H. Brunengraber, 1976, FEBS letters.

Quantitation of 1,3-butanediol and its acidic metabolites by gas chromatography-mass spectrometry.

H. Brunengraber, C. Des Rosiers, J. Montgomery, 1990, Analytical biochemistry.

Lipogenesis from ketone bodies in the isolated perfused rat liver. Evidence for the cytosolic activation of acetoacetate.

H. Brunengraber, J. Edmond, G. Endemann, 1982, The Journal of biological chemistry.

Treatment of cardiomyopathy and rhabdomyolysis in long-chain fat oxidation disorders using an anaplerotic odd-chain triglyceride.

C. Roe, H. Brunengraber, F. David, 2002, The Journal of clinical investigation.

Radioenzymatic assay of plasma mevalonate.

H. Brunengraber, R. Kopito, T. Parker, 1985, Methods in enzymology.

Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4.

A. Malik, Guo-Fang Zhang, Hojin Kang, 2016, Cell reports.

Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors

C. Flask, Jessica Bowers, R. Getts, 2022, Nature Cancer.

A roadmap for interpreting (13)C metabolite labeling patterns from cells.

Joerg M. Buescher, Christian M. Metallo, Jamey D. Young, 2015, Current opinion in biotechnology.

Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer

K. Kinzler, B. Vogelstein, V. Velculescu, 2016, Nature Communications.

A Role for Cytosolic Isocitrate Dehydrogenase as a Negative Regulator of Glucose Signaling for Insulin Secretion in Pancreatic ß-Cells

M. Prentki, H. Brunengraber, S. Madiraju, 2013, PloS one.

Metabolic Profiling of Skeletal Muscle During Ex-Vivo Normothermic Limb Perfusion.

H. Brunengraber, A. Rampazzo, S. Dasarathy, 2021, Military medicine.

Ex vivo normothermic preservation of amputated limbs with a hemoglobin-based oxygen carrier perfusate

H. Brunengraber, A. Rampazzo, S. Dasarathy, 2021, The journal of trauma and acute care surgery.

Analysis of the citric acid cycle intermediates using gas chromatography-mass spectrometry.

R. Kombu, H. Brunengraber, M. Puchowicz, 2011, Methods in molecular biology.

Metabolomic and Mass Isotopomer Analysis of Liver Gluconeogenesis and Citric Acid Cycle

J. Kelleher, R. Kombu, H. Brunengraber, 2008, Journal of Biological Chemistry.

Health and Disease : Overview and Future Directions

Matthew B Schade, J. Sanabria, Z. Hunter, 2019 .

Cellular Senescence and Their Role in Liver Metabolism in Health and Disease: Overview and Future Directions

J. Sanabria, H. Brunengraber, J. Fannin, 2018, Hepatocellular Carcinoma - Advances in Diagnosis and Treatment.

Metabolomics, Pathway Regulation, and Pathway Discovery*

Gregory P Tochtrop, Henri Brunengraber, Guo-Fang Zhang, 2011, The Journal of Biological Chemistry.

Assay of physiological levels of 2,3-butanediol diastereomers in blood and urine by gas chromatography-mass spectrometry.

H. Brunengraber, J. Montgomery, M. Jetté, 1990, Analytical biochemistry.

Ultrastructure and intercellular vacuolization of isolated perfused and control rat testes.

H. Brunengraber, A. Hoffer, B. Carlton, 1983, Journal of andrology.

Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association.

Thomas J. Wang, S. Neubauer, R. Gropler, 2016, Circulation research.

Is there glucose production outside of the liver and kidney?

H. Brunengraber, S. Previs, D. Z. Brunengraber, 2009, Annual review of nutrition.

Identification of S-nitroso-CoA reductases that regulate protein S-nitrosylation

A. Hausladen, J. Stamler, Guo-Fang Zhang, 2014, Proceedings of the National Academy of Sciences.

Metabolomic assays of the concentration and mass isotopomer distribution of gluconeogenic and citric acid cycle intermediates

J. Kelleher, H. Brunengraber, F. David, 2006, Metabolomics.

Applications of mass isotopomer analysis to nutrition research.

J K Kelleher, J. Kelleher, H. Brunengraber, 1997, Annual review of nutrition.

Metabolism of γ-hydroxybutyrate in perfused rat livers.

Guo-Fang Zhang, H. Brunengraber, V. Anderson, 2012, The Biochemical journal.

Mass isotopomer study of anaplerosis from propionate in the perfused rat heart.

Henri Brunengraber, H. Brunengraber, F. David, 2007, Archives of biochemistry and biophysics.

Metabolomics of Apc Min/+ mice genetically susceptible to intestinal cancer

Jean-Eudes J. Dazard, Yana Sandlers, Stephanie K. Doerner, 2014, BMC Systems Biology.

Association of Uremic Solutes With Cardiovascular Death in Diabetic Kidney Disease.

R. Vasan, P. Kimmel, T. Hostetter, 2022, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Methods for measuring gluconeogenesis in vivo.

H. Brunengraber, S. Previs, S F Previs, 1998, Current opinion in clinical nutrition and metabolic care.

Cancer cells are sensitive to wild-type IDH1 inhibition under nutrient limitation

R. Getts, H. Brunengraber, J. Salvino, 2020, bioRxiv.

Pharmacokinetic model for N-nitrosodimethylamine based on Michaelis-Menten constants determined with the isolated perfused rat liver.

S. Tannenbaum, H. Brunengraber, P. Skipper, 1983, Cancer research.

Inhibition of N-nitrosodimethylamine metabolism by ethanol and other inhibitors in the isolated perfused rat liver.

S. Tannenbaum, H. Brunengraber, P. Skipper, 1984, Carcinogenesis.

Uptake of free choline by isolated perfused rat liver.

R. Wurtman, S. Zeisel, H. Brunengraber, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Quantitative assessment of anaplerosis from propionate in pig heart in vivo.

Henri Brunengraber, William C Stanley, C. Hoppel, 2003, American journal of physiology. Endocrinology and metabolism.

Hyperoxia induces glutamine-fuelled anaplerosis in retinal Müller cells

A. Yuan, H. Brunengraber, J. Sears, 2020, Nature Communications.

Delineation of substrate selection and anaplerosis in tricarboxylic acid cycle of the heart by 13C NMR spectroscopy and mass spectrometry

Xin Yu, H. Brunengraber, F. Bian, 2011, NMR in biomedicine.

Assay of the acetyl-CoA probe acetyl-sulfamethoxazole and of sulfamethoxazole by gas chromatography-mass spectrometry.

Y. Zhang, M. Beylot, H. Brunengraber, 1993, Analytical Biochemistry.

Assay of the enantiomers of 1,2-propanediol, 1,3-butanediol, 1,3-pentanediol, and the corresponding hydroxyacids by gas chromatography-mass spectrometry.

H. Brunengraber, F. David, A. Kumar, 1994, Analytical biochemistry.

Assay of the activity of malonyl-coenzyme A decarboxylase by gas chromatography-mass spectrometry.

H. Brunengraber, Cory J Darrow, W. Stanley, 2007, Analytical Biochemistry.

An improved procedure for the synthesis of labelled fatty acids utilizing diethyl malonate

H. Brunengraber, T. Kasumov, 2006 .

Biosynthesis and characterization of 3-hydroxyalkan-2-ones and 2,3-alkanediols: potential products of aldehyde metabolism.

H. Brunengraber, C. Des Rosiers, J. Montgomery, 1992, Biological mass spectrometry.

Anaplerotic treatment of long-chain fat oxidation disorders with triheptanoin: Review of 15 years Experience.

C. Roe, H. Brunengraber, 2015, Molecular genetics and metabolism.

Peroxisomal and Mitochondrial Oxidation of Fatty Acids in the Heart, Assessed from the 13C Labeling of Malonyl-CoA and the Acetyl Moiety of Citrate*

C. Hoppel, H. Brunengraber, F. David, 2005, Journal of Biological Chemistry.

Anaplerotic molecules: Current and future

C. Roe, H. Brunengraber, 2006, Journal of Inherited Metabolic Disease.

Stable isotope studies of phytanic acid α-oxidation: in vivo production of formic acid

H. Brunengraber, S. Previs, N. Verhoeven, 1997, European Journal of Pediatrics.

One-stage hepatectomy in the dog.

H. Brunengraber, C. Des Rosiers, P. Daloze, 1990, The Journal of surgical research.

The role of acetone in the conversion of fat to carbohydrate

Henri Brunengraber, B. Landau, H. Brunengraber, 1987 .

Energy metabolism and blood perfusion in a mouse mammary adenocarcinoma during growth and following X irradiation.

H. Brunengraber, G. Tozer, M. Barlai-Kovach, 1987, Radiation research.

Dynamics of glutathione and ophthalmate traced with 2H-enriched body water in rats and humans.

Henri Brunengraber, Guo-Fang Zhang, J. Kelleher, 2009, American journal of physiology. Endocrinology and metabolism.

New mechanisms by which statins lower plasma cholesterol1

H. Brunengraber, 2016, Journal of Lipid Research.

Zonation of Labeling of Lipogenic Acetyl-CoA across the Liver

J. Kelleher, D. Wasserman, H. Brunengraber, 2004, Journal of Biological Chemistry.

Contributions of cytosolic and mitochondrial acetyl-CoA syntheses to the activation of lipogenic acetate in rat liver.

H. Brunengraber, R. Goldberg, 1980, Advances in experimental medicine and biology.

Potential of ketone body esters for parenteral and oral nutrition.

H. Brunengraber, 1997, Nutrition.

The shunt pathway of mevalonate metabolism in the isolated perfused rat kidney.

H. Brunengraber, R. Kopito, D. M. Murray, 1984, The Journal of biological chemistry.

The shunt pathway of mevalonate metabolism in the isolated perfused rat liver.

H. Brunengraber, R. Kopito, D. M. Murray, 1984, Journal of Biological Chemistry.

Case - Heavy Water Assays by GC-mass spectrometry v1

H. Brunengraber, 2019, protocols.io.

from the American Heart Association

Thomas J. Wang, S. Neubauer, R. Gropler, 1990 .

(R)-mevalonate excretion in human and rat urines.

H. Brunengraber, R. Kopito, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Metabolism of 2,3-butanediol stereoisomers in the perfused rat liver.

H. Brunengraber, F. David, M. Garneau, 1993, The Journal of biological chemistry.

Serine and 1-carbon metabolism are required for HIF-mediated protection against retinopathy of prematurity.

H. Brunengraber, Amit Sharma, J. Sears, 2019, JCI insight.

Propionate-induced changes in cardiac metabolism, notably CoA trapping, are not altered by l-carnitine.

Guo-Fang Zhang, D. Muoio, H. Brunengraber, 2018, American journal of physiology. Endocrinology and metabolism.

Multiple Mass Isotopomer Tracing of Acetyl-CoA Metabolism in Langendorff-perfused Rat Hearts

Guo-Fang Zhang, H. Brunengraber, V. Anderson, 2015, The Journal of Biological Chemistry.

Using isotopic tools to dissect and quantitate parallel metabolic pathways.

Guo-Fang Zhang, H. Brunengraber, Gregory P. Tochtrop, 2010, Journal of the American Chemical Society.

Weight gain is an early indicator of injury in ex vivo normothermic limb perfusion (EVNLP)

V. Kopparthy, H. Brunengraber, A. Rampazzo, 2022, Artificial organs.

Parenteral and enteral metabolism of anaplerotic triheptanoin in normal rats. II. Effects on lipolysis, glucose production, and liver acyl-CoA profile.

Frederick Allen, G. Kutz, Wolf-Ulrich Brewer, 2010, American journal of physiology. Endocrinology and metabolism.

Metabolism of Levulinate in Perfused Rat Livers and Live Rats

S. R. Harris, Guo-Fang Zhang, H. Brunengraber, 2010, The Journal of Biological Chemistry.

Compartmentation of Metabolism of the C12-, C9-, and C5-n-dicarboxylates in Rat Liver, Investigated by Mass Isotopomer Analysis

J. Kelleher, Guo-Fang Zhang, H. Brunengraber, 2015, Journal of Biological Chemistry.

Nonhomogeneous labeling of liver extra-mitochondrial acetyl-CoA. Implications for the probing of lipogenic acetyl-CoA via drug acetylation and for the production of acetate by the liver.

Y. Zhang, M. Beylot, H. Brunengraber, 1994, The Journal of biological chemistry.

with delays in

H. Brunengraber, M. Puchowicz, C. Ari, 2013 .