J. Roman

A. Ramirez, J. Roman, J. Ritzenthaler, 2006, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Smad3 deficiency ameliorates experimental obliterative bronchiolitis in a heterotopic tracheal transplantation model.

J. Varga, J. Roman, H. Jaffe, 2004, The American journal of pathology.

PPARbeta/delta agonist stimulates human lung carcinoma cell growth through inhibition of PTEN expression: the involvement of PI3K and NF-kappaB signals.

Ying Zheng, J. Roman, J. Ritzenthaler, 2008, American journal of physiology. Lung cellular and molecular physiology.

An American Thoracic Society Official Research Statement: Future Directions in Lung Fibrosis Research.

F. Martinez, K. Brown, O. Eickelberg, 2016, American journal of respiratory and critical care medicine.

Pulmonary Fibrosis in Hermansky-Pudlak Syndrome.

J. Roman, L. Young, Glenn W. Vicary, 2016, Annals of the American Thoracic Society.

In-hospital mortality, length of stay, and charges related to pulmonary fibrosis in the U.S. between 1993 and 2008

D. Mannino, J. Roman, Daniel Fioret, 2016 .

Open-access biorepository for idiopathic pulmonary fibrosis. The way forward.

H. Collard, F. Martinez, S. Violette, 2014, Annals of the American Thoracic Society.

The importance of diagnosis in interstitial lung disease.

J. Roman, 2014 .

An official American thoracic society workshop report: comparative pathobiology of fibrosing lung disorders in humans and domestic animals.

K. Brown, J. Roman, B. Corcoran, 2013, Annals of the American Thoracic Society.

Fibronectin induces cell proliferation and inhibits apoptosis in human bronchial epithelial cells: pro-oncogenic effects mediated by PI3-kinase and NF-κB

S. Han, J. Roman, SW Han, 2006, Oncogene.

Bone marrow-derived mesenchymal stem cells in repair of the injured lung.

M. Rojas, J. Roman, K. Brigham, 2005, American journal of respiratory cell and molecular biology.

The Puerto Rico Healthcare Crisis.

J. Roman, 2015, Annals of the American Thoracic Society.

Respiratory health equality in the United States. The American thoracic society perspective.

J. Samet, J. Celedón, J. Roman, 2014, Annals of the American Thoracic Society.

COPD in VA hospitals.

J. Roman, R. Pérez, 2003, Clinical cornerstone.

Lung Cytokines and Systemic Inflammation in Patients with COPD

T. Wiemken, R. Cavallazzi, R. Fernandez-Botran, 2017 .

Prognostic Factors for Hospital Mortality and ICU Admission in Patients With ANCA-Related Pulmonary Vasculitis

J. Roman, A. Gal, F. Holguin, 2008, The American journal of the medical sciences.

Activation of Tissue Remodeling Precedes Obliterative Bronchiolitis in Lung Transplant Recipients

M. Rojas, J. Roman, D. Nunley, 2008, Biomarker insights.

Chronic ethanol ingestion increases susceptibility to acute lung injury: role of oxidative stress and tissue remodeling.

J. Roman, D. Guidot, 2002, Chest.

Studying human respiratory disease in animals – role of induced and naturally occurring models

J. Roman, K. Williams, 2016, The Journal of pathology.

Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-gamma receptor-deficient mice.

M. Rojas, J. Roman, K. Brigham, 2007, American journal of respiratory and critical care medicine.

Lung infection with γ-herpesvirus induces progressive pulmonary fibrosis in Th2-biased mice

M. Rojas, J. Roman, K. Brigham, 2005 .

A Case of Progressive Lung Fibrosis

J. Roman, R. Pérez, Daniel Fioret, 2011, The American journal of the medical sciences.

Challenges in translating preclinical studies to effective drug therapies in idiopathic pulmonary fibrosis.

V. Thannickal, J. Roman, 2010, American journal of respiratory and critical care medicine.

The Fibronectin EDA Splicing Variant Induces Epithelial-mesenchymal Transition In Lung Cancer Cells Through Integrin ±9²1-mediated Activation Of PI3-K And Erk1/2

E. White, J. Roman, J. Ritzenthaler, 2010, ATS 2010.

Retraction. The fibronectin EDA splicing variant induces epithelial-mesenchymal transition in lung cancer cells through integrin α9β1-mediated activation of PI3-K and Erk.

E. White, J. Roman, J. Ritzenthaler, 2010, American Journal of Physiology - Lung cellular and Molecular Physiology.

Fibronectin stimulates human lung carcinoma cell proliferation by suppressing p21 gene expression via signals involving Erk and Rho kinase.

J. Roman, N. Sidell, Shouwei Han, 2005, Cancer letters.

Nicotine stimulates collagen type I expression in lung via α7 nicotinic acetylcholine receptors

T. Panchabhai, J. Roman, J. Ritzenthaler, 2017, Respiratory Research.

Peroxisome Proliferator-Activated Receptor &ggr; Ligands Increase Release of Nitric Oxide From Endothelial Cells

J. Roman, C. Hart, S. Roser, 2003, Arteriosclerosis, thrombosis, and vascular biology.

From Endothelial Cells Ligands Increase Release of Nitric Oxide γ Peroxisome Proliferator-Activated Receptor

J. Roman, C. Hart, S. Roser, 2002 .

E-cigarettes and Vaping Associated Lung Injury: A Case Series and Brief Review.

B. Sundaram, J. Roman, R. Summer, 2020, The American journal of the medical sciences.

Pulmonary hypertension and vascular remodeling in mice exposed to crystalline silica

J. Roman, J. Ritzenthaler, I. Zelko, 2016, Respiratory Research.

Increased pathology in lungs of mice after infection with an alpha-crystallin mutant of Mycobacterium tuberculosis: changes in cathepsin proteases and certain cytokines.

J. Roman, C. Rivera-Marrero, F. Quinn, 2006, Microbiology.

The Down-Regulation of Cathepsin G in THP-1 Monocytes after Infection with Mycobacterium tuberculosis Is Associated with Increased Intracellular Survival of Bacilli

W. Shafer, J. Roman, C. Rivera-Marrero, 2004, Infection and Immunity.

Fibronectin increases matrix metalloproteinase 9 expression through activation of c-Fos via extracellular-regulated kinase and phosphatidylinositol 3-kinase pathways in human lung carcinoma cells.

J. Roman, J. Ritzenthaler, S. Sitaraman, 2011, The Journal of Biological Chemistry.

Rosiglitazone inhibits α4 nicotinic acetylcholine receptor expression in human lung carcinoma cells through peroxisome proliferator-activated receptor γ-independent signals

Ying Zheng, J. Roman, J. Ritzenthaler, 2009, Molecular Cancer Therapeutics.

Nicotine Stimulates PPAR B / D Expression in Human Lung Carcinoma Cells through Activation of PI3K/mTOR and Suppression of AP-2 A

Ying Zheng, J. Roman, J. Ritzenthaler, 2009 .

Nicotine stimulates PPARbeta/delta expression in human lung carcinoma cells through activation of PI3K/mTOR and suppression of AP-2alpha.

Ying Zheng, J. Roman, J. Ritzenthaler, 2009, Cancer research.

Induction of MMP-9 mediated gelatinolytic activity in human monocytic cells by cell wall components of M. tuberculosis

J. Roman, C. Rivera-Marrero, S. Roser, 2000 .

Comparative Biology of the Normal Lung Extracellular Matrix

E. White, J. Roman, R. Hadley, 2015 .

Respiratory Health in Migrant Populations: A Crisis Overlooked

Sanjay R. Patel, I. Douglas, J. Celedón, 2017, Annals of the American Thoracic Society.

APOPTOSIS OF MESENCHYMAL CELLS DURING THE PSEUDOGLANDULAR STAGE OF LUNG DEVELOPMENT AFFECTS BRANCHING MORPHOGENESIS

J. Roman, C. Wongtrakool, 2008, Experimental lung research.

M. tuberculosis induction of matrix metalloproteinase-9: the role of mannose and receptor-mediated mechanisms.

J. Roman, C. Rivera-Marrero, J. Ritzenthaler, 2002, American journal of physiology. Lung cellular and molecular physiology.

Activation of peroxisome proliferator-activated receptor beta/delta induces lung cancer growth via peroxisome proliferator-activated receptor coactivator gamma-1alpha.

Ying Zheng, J. Roman, J. Ritzenthaler, 2009, American journal of respiratory cell and molecular biology.

Activation of Peroxisome Proliferator–Activated Receptor b / d Induces Lung Cancer Growth via Peroxisome Proliferator–Activated Receptor Coactivator g -1 a

Ying Zheng, J. Roman, J. Ritzenthaler, 2009 .

Induction of MMP-9 mediated gelatinolytic activity in human monocytic cells by cell wall components of Mycobacterium tuberculosis.

J. Roman, C. Rivera-Marrero, S. Roser, 2000, Microbial pathogenesis.

Peroxisome Proliferator–Activated Receptor-γ Ligands Inhibit α5 Integrin Gene Transcription in Non–Small Cell Lung Carcinoma Cells

J. Roman, H. Rivera, Shouwei Han, 2005 .

Biomarkers of pulmonary rejection.

J. Roman, A. Roman, M. Culebras, 2013, Transplantation proceedings.

Phorbol ester-induced U-937 differentiation: Effects on integrin α5 gene transcription

J. Roman, J. Ritzenthaler, T. Birkenmeier, 2000 .

Phorbol ester-induced U-937 differentiation: effects on integrin alpha(5) gene transcription.

J. Roman, J. Ritzenthaler, T. Birkenmeier, 2000, American journal of physiology. Lung cellular and molecular physiology.

Prostaglandin E2 stimulates human lung carcinoma cell growth through induction of integrin-linked kinase: the involvement of EP4 and Sp1.

Ying Zheng, J. Roman, J. Ritzenthaler, 2009, Cancer research.

Sarcoidosis: a mysterious tale of inflammation, tissue remodeling, and matrix metalloproteinases.

Z. Galis, J. Roman, 2002, Human pathology.

Zinc supplementation restores PU.1 and Nrf2 nuclear binding in alveolar macrophages and improves redox balance and bacterial clearance in the lungs of alcohol-fed rats.

J. Roman, J. Ritzenthaler, L. Brown, 2011, Alcoholism, clinical and experimental research.

Fibrin enhances the expression of IL-1 beta by human peripheral blood mononuclear cells. Implications in pulmonary inflammation.

J. Roman, R. Pérez, R. Perez, 1995, Journal of immunology.

bleomycin-induced lung fibrosis Oxidation of extracellular cysteine/cystine redox state in

Dean P. Jones, M. Rojas, J. Roman, 2016 .

Oxidation of extracellular cysteine/cystine redox state in bleomycin-induced lung fibrosis.

Dean P. Jones, M. Rojas, J. Roman, 2009, American journal of physiology. Lung cellular and molecular physiology.

Fibronectin and fibronectin receptors in lung development.

J. Roman, J. Roman, 1997, Experimental lung research.

Treating refractory asthma with antibodies against IL-5: is it ready for prime time?

J. Roman, F. Ahmad, 2009, Expert review of respiratory medicine.

GM-CSF receptor expression and signaling is decreased in lungs of ethanol-fed rats.

J. Roman, D. Eaton, D. Guidot, 2006, American journal of physiology. Lung cellular and molecular physiology.

Chronic Ethanol Ingestion in Rats Decreases Granulocyte-Macrophage Colony-Stimulating Factor Receptor Expression and Downstream Signaling in the Alveolar Macrophage1

Bjoern Peters, D. Tscharke, J. Sidney, 2005, Journal of Immunology.

Chronic ethanol ingestion increases expression of the angiotensin II type 2 (AT2) receptor and enhances tumor necrosis factor-alpha- and angiotensin II-induced cytotoxicity via AT2 signaling in rat alveolar epithelial cells.

J. Roman, D. Eaton, R. Bechara, 2003, Alcoholism, clinical and experimental research.

Extracellular cysteine/cystine redox potential controls lung fibroblast proliferation and matrix expression through upregulation of transforming growth factor-beta.

Dean P. Jones, J. Roman, J. Ritzenthaler, 2007, American journal of physiology. Lung cellular and molecular physiology.

Nicotine alters lung branching morphogenesis through the alpha7 nicotinic acetylcholine receptor.

J. Roman, C. Wongtrakool, H. Rivera, 2007, American journal of physiology. Lung cellular and molecular physiology.

Transforming Growth Factor-β1, Myofibroblasts, and Tissue Remodeling in the Pathogenesis of Tracheal Injury: Potential Role of Gastroesophageal Reflux

J. Roman, A. Gal, H. Rivera, 2004, The Annals of otology, rhinology, and laryngology.

PPAR (cid:1) / (cid:2) agonist stimulates human lung carcinoma cell growth through inhibition of PTEN expression: the involvement of PI3K and NF- (cid:3) B signals

Ying Zheng, J. Roman, J. Ritzenthaler, 2008 .

PPAR / agonist stimulates human lung carcinoma cell growth through inhibition of PTEN expression: the involvement of PI3K and NF- B signals

J. Roman, J. Ritzenthaler, Ying Zheng, 2008 .

Activation of peroxisome proliferator-activated receptor β/δ (PPARβ/δ) increases the expression of prostaglandin E2 receptor subtype EP4. THE ROLES OF PHOSPHATIDYLINOSITOL 3-KINASE AND CCAAT/ENHANCER-BINDING PROTEIN β.

J. Roman, J. Ritzenthaler, B. Wingerd, 2005, The Journal of Biological Chemistry.

The Coronavirus Pandemic – At the Beginning of the Learning Curve

J. Roman, Rafael L. Perez, 2020, The American Journal of the Medical Sciences.

Angiotensin-converting enzyme N-terminal inactivation alleviates bleomycin-induced lung injury.

J. Roman, K. Bernstein, A. Gal, 2010, The American journal of pathology.

Acute Exacerbation of Interstitial Lung Disease as a Sequela of COVID-19 Pneumonia

J. Roman, R. Summer, M. Fonseca, 2020, The American Journal of the Medical Sciences.

Twist: A Regulator of Epithelial-Mesenchymal Transition in Lung Fibrosis

M. Rojas, J. Roman, A. Stecenko, 2009, PloS one.

B Cells in Idiopathic Pulmonary Fibrosis: Targeting Immune Cells with Antifibrotic Agents

J. Roman, H. Chiba, 2021, American journal of respiratory cell and molecular biology.

Aging promotes pro-fibrotic matrix production and increases fibrocyte recruitment during acute lung injury

M. Rojas, J. Roman, D. Neujahr, 2014, Advances in bioscience and biotechnology.

CHARACTERISTICS OF PATIENTS WITH IDIOPATHIC PULMONARY FIBROSIS (IPF) IN THE US: DATA FROM THE IPF-PRO REGISTRY

E. Yow, T. Whelan, J. Belperio, 2018, Chest.

Regulation of lung branching morphogenesis by bombesin-like peptides and neutral endopeptidase.

J. Roman, S. Aguayo, J. Murtagh, 1994, American journal of respiratory cell and molecular biology.

Matrix metalloproteinase-9 regulates MUC-2 expression through its effect on goblet cell differentiation.

J. Roman, P. Garg, D. Merlin, 2007, Gastroenterology.

Adenosine induces fibronectin expression in lung epithelial cells: implications for airway remodeling.

J. Roman, J. Ritzenthaler, S. Sitaraman, 2006, American journal of physiology. Lung cellular and molecular physiology.

Plasma cysteine/cystine and glutathione/glutathione disulfide redox potentials in HIV and COPD patients.

T. Wiemken, J. Ramirez, W. Watson, 2019, Free radical biology & medicine.

Increased fibronectin expression in lung in the setting of chronic alcohol abuse.

J. Roman, M. Moss, J. Ritzenthaler, 2007, Alcoholism, clinical and experimental research.

Fibrin-mediated integrin signaling plays a critical role in hepatic regeneration after partial hepatectomy in mice.

G. Arteel, S. Joshi‐Barve, J. Roman, 2016, Annals of hepatology.

Epithelial-derived Fibronectin Expression, Signaling, and Function in Intestinal Inflammation*

J. Roman, D. Merlin, J. Ritzenthaler, 2007, Journal of Biological Chemistry.

Sex-Based Differences in Interstitial Lung Disease.

J. Roman, R. Pérez, P. Pandit, 2020, The American journal of the medical sciences.

Alcohol primes the airway for increased interleukin-13 signaling.

J. Roman, J. Ritzenthaler, D. Guidot, 2009, Alcoholism, clinical and experimental research.

Transcriptional regulation of the human interleukin 1beta gene by fibronectin: role of protein kinase C and activator protein 1 (AP-1).

J. Roman, M. Fenton, J. Ritzenthaler, 2000, Cytokine.

Transforming Growth Factor β1 Expression and Activation Is Increased in the Alcoholic Rat Lung

J. Roman, R. Bechara, L. Brown, 2004 .

Cytokine message and protein expression during lung granuloma formation and resolution induced by the mycobacterial cord factor trehalose-6,6'-dimycolate.

R. Hunter, J. Roman, J. Actor, 2000, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Donor factors and risk of primary graft dysfunction and mortality post lung transplantation: A proposed conceptual framework

J. Roman, D. Nunley, M. Venkata-Subramani, 2021, Clinical transplantation.

Role of SOD3 in silica-related lung fibrosis and pulmonary vascular remodeling

J. Roman, I. Zelko, Jianxin Zhu, 2018, Respiratory Research.

Lipopolysaccharide induces expression of fibronectin alpha 5 beta 1-integrin receptors in human monocytic cells in a protein kinase C-dependent fashion.

J. Roman, J. Ritzenthaler, M. Lois, 2004, American journal of physiology. Lung cellular and molecular physiology.

Polarized fibronectin secretion induced by adenosine regulates bacterial-epithelial interaction in human intestinal epithelial cells.

J. Roman, D. Merlin, A. Gewirtz, 2004, The Biochemical journal.

Cysteine Redox Potential Determines Pro-Inflammatory IL-1β Levels

Dean P. Jones, M. Rojas, T. Ziegler, 2009, PloS one.

Slowly Adapting Sensory Units Have More Receptors in Large Airways than in Small Airways in Rabbits

J. Roman, J. Guardiola, N. Song, 2016, Front. Physiol..

Impact of sex, age and diet on the cysteine/cystine and glutathione/glutathione disulfide plasma redox couples in mice.

W. Watson, J. Roman, J. Ritzenthaler, 2020, The Journal of nutritional biochemistry.

Age‐dependent oxidation of extracellular cysteine/cystine redox state (Eh(Cys/CySS)) in mouse lung fibroblasts is mediated by a decline in Slc7a11 expression

W. Watson, J. Roman, J. Otero, 2018, Free radical biology & medicine.

Chronic ethanol ingestion in rats decreases granulocyte-macrophage colony-stimulating factor receptor expression and downstream signaling in the alveolar macrophage.

Bjoern Peters, V. Pasquetto, D. Tscharke, 1997, Journal of Immunology.

Alveolar type II cells from ethanol-fed rats produce a fibronectin-enriched extracellular matrix that promotes monocyte activation.

J. Roman, J. Ritzenthaler, L. Brown, 2007, Alcohol.

Fibulin's organization into the extracellular matrix of fetal lung fibroblasts is dependent on fibronectin matrix assembly.

J. Roman, J. McDonald, 1993, American journal of respiratory cell and molecular biology.

Extracellular matrix fibronectin increases prostaglandin E2 receptor subtype EP4 in lung carcinoma cells through multiple signaling pathways. THE ROLE OF AP-2.

J. Roman, J. Ritzenthaler, B. Wingerd, 2007, The Journal of Biological Chemistry.

Fibronectin stimulates human lung carcinoma cell growth by inducing cyclooxygenase‐2 (COX‐2) expression

J. Roman, N. Sidell, Shouwei Han, 2004, International journal of cancer.

injury 1 protects Dahl S rats against high salt-induced renal βknockout of transforming growth factor-

H. Jacob, J. Roman, A. Geurts, 2014 .

Tumor cell cross talk with tumor-associated leukocytes leads to induction of tumor exosomal fibronectin and promotes tumor progression.

W. Grizzle, Hong Jiang, J. Roman, 2012, The American journal of pathology.

Fibronectin Increases Matrix Metalloproteinase 9 Expression through Activation of c-Fos via Extracellular-regulated Kinase and Phosphatidylinositol 3-Kinase Pathways in Human Lung Carcinoma Cells*

J. Roman, J. Ritzenthaler, S. Sitaraman, 2006, Journal of Biological Chemistry.

Role of Oxidative Stress and Tissue Remodeling

J. Roman, D. Guidot, 2017 .

Nicotinic acetylcholine receptors are sensors for ethanol in lung fibroblasts.

J. Roman, J. Ritzenthaler, D. Guidot, 2013, Alcoholism, clinical and experimental research.

Award Number: DAMD17-02-1-0179 TITLE: Mechanism of Tissue Remodeling in Sepsis-Induced Acute Lung Injury

Principal Investigator, J. Roman, 2006 .

Mechanism of Tissue Remodeling in Sepsis-Induced Acute Lung Injury

J. Roman, 2005 .

Lung infection with gamma-herpesvirus induces progressive pulmonary fibrosis in Th2-biased mice.

M. Rojas, J. Roman, K. Brigham, 2005, American journal of physiology. Lung cellular and molecular physiology.

TGFβ1 Controls PPARγ Expression, Transcriptional Potential, and Activity, in Part, through Smad3 Signaling in Murine Lung Fibroblasts

J. Roman, A. Ramirez, Erin N. Ballard, 2012, PPAR research.

The pro-fibrotic and senescence phenotype of old lung fibroblasts is reversed or ameliorated by genetic and pharmacological manipulation of Slc7a11 expression.

W. Watson, A. Halayko, J. Roman, 2022, American journal of physiology. Lung cellular and molecular physiology.

Peroxisome proliferator-activated receptor-gamma ligands suppress fibronectin gene expression in human lung carcinoma cells: involvement of both CRE and Sp1.

J. Roman, J. Ritzenthaler, H. Rivera, 2005, American journal of physiology. Lung cellular and molecular physiology.

Fibroblast-derived conditioned media promotes lung cancer progression.

J. Roman, J. Ritzenthaler, J. Greenwell, 2022, The American journal of the medical sciences.

PPARγ

J. Roman, P. Sime, C. Hart, 2008, Journal of Investigative Medicine.

Enhanced pulmonary and systemic response to endotoxin in transgenic sickle mice.

J. D. Holtzclaw, J. Roman, S. Aguayo, 2004, American journal of respiratory and critical care medicine.

Suppression of prostaglandin E2 receptor subtype EP2 by PPARgamma ligands inhibits human lung carcinoma cell growth.

J. Roman, Shouwei Han, 2004, Biochemical and biophysical research communications.

The Fibrosis Across Organs Symposium: A Roadmap for Future Research Priorities

D. Brenner, K. Brown, L. Richeldi, 2019, The American journal of the medical sciences.

Extracellular matrix and lung inflammation

J. Roman, 1996, Immunologic research.

Transcriptional regulation of the interleukin-1beta promoter via fibrinogen engagement of the CD18 integrin receptor.

J. Roman, J. Ritzenthaler, J. Ritzenthaler, 1999, American journal of respiratory cell and molecular biology.

Anticancer actions of PPARγ ligands: Current state and future perspectives in human lung cancer.

J. Roman, Shouwei Han, 2010, World journal of biological chemistry.

Peroxisome proliferator-activated receptor &ggr;: a novel target for cancer therapeutics?

J. Roman, Shouwei Han, 2007, Anti-cancer drugs.

Rosiglitazone suppresses human lung carcinoma cell growth through PPARγ-dependent and PPARγ-independent signal pathways

J. Roman, ShouWei Han, Jesse Roman, 2006, Molecular Cancer Therapeutics.

Up-regulation of p21 Gene Expression by Peroxisome Proliferator-Activated Receptor γ in Human Lung Carcinoma Cells

P. Fisher, J. Roman, N. Sidell, 2004, Clinical Cancer Research.

Extravascular coagulation and fibrinolysis in murine lung inflammation induced by the mycobacterial cord factor trehalose-6,6'-dimycolate.

R. Hunter, J. Roman, G. Staton, 1994, American journal of respiratory and critical care medicine.

From nihilism to individualism: the evolution of lung cancer therapy.

F. Khuri, J. Roman, 2008, American journal of respiratory and critical care medicine.

Lung extracellular matrix and redox regulation

W. Watson, J. Roman, J. Ritzenthaler, 2016, Redox biology.

Peroxisome Proliferator-Activated Receptor &ggr; and Lung Cancer Biology: Implications for Therapy

J. Roman, 2008, Journal of investigative medicine : the official publication of the American Federation for Clinical Research.

Peroxisome Proliferator-Activated Receptors in Lung Cancer

V. Keshamouni, J. Roman, Shouwei Han, 2007, PPAR research.

alpha5beta1-integrin expression is essential for tumor progression in experimental lung cancer.

J. Roman, J. Ritzenthaler, Xiaojuan Sun, 2010, American journal of respiratory cell and molecular biology.

Recruitment and Retention in Academic Medicine—What Junior Faculty and Trainees Want Department Chairs to Know

J. Roman, D. Kamen, D. Guidot, 2012 .

Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways.

Fadlo R Khuri, F. Khuri, J. Roman, 2006, Cancer research.

Stimulation of lung carcinoma cell growth by fibronectin-integrin signalling.

J. Roman, J. Ritzenthaler, Shouwei Han, 2008, Molecular bioSystems.

Fish Oil Inhibits Human Lung Carcinoma Cell Growth by Suppressing Integrin-Linked Kinase

J. Roman, J. Ritzenthaler, Xiaojuan Sun, 2009, Molecular Cancer Research.

A systematic review of overlapping microRNA patterns in systemic sclerosis and idiopathic pulmonary fibrosis

S. Gangemi, J. Roman, W. Roberts, 2017, European Respiratory Review.

Interplay between aging, lung inflammation/remodeling, and fibronectin EDA in lung cancer progression

J. Roman, J. Ritzenthaler, E. Torres-González, 2020, Cancer biology & therapy.

Molecular cloning and expression of a novel glycolipid sulfotransferase in Mycobacterium tuberculosis.

R. Cummings, J. Roman, C. Rivera-Marrero, 2002, Microbiology.

Chronic Alcohol Exposure Enhances Lipopolysaccharide-Induced Lung Injury in Mice: Potential Role of Systemic Tumor Necrosis Factor-Alpha.

Robin H. Schmidt, G. Arteel, J. Roman, 2015, Alcoholism, clinical and experimental research.

Targeting the Mammalian Target of Rapamycin in Lung Cancer☆

J. Roman, Glenn W. Vicary, 2016, The American journal of the medical sciences.

Effects of calcium channel blockade on mammalian lung branching morphogenesis.

J. Roman, 1995, Experimental lung research.

Potential Role of the Gut/Liver/Lung Axis in Alcohol-Induced Tissue Pathology

G. Arteel, J. Roman, J. Ritzenthaler, 2015, Biomolecules.

Heparin inhibits lung branching morphogenesis: potential role of smooth muscle cells in cleft formation.

J. Roman, J. McDonald, S. Roser, 1998, The American journal of the medical sciences.

Conducting Clinical Research in the Era of Covid-19

J. Roman, R. Pérez, T. Perez, 2020, The American Journal of the Medical Sciences.

Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP.

M. Rojas, J. Roman, P. Garg, 2005, Gastroenterology.

Mechanisms Underlying HIV-Associated Noninfectious Lung Disease.

B. Lau, B. Palmer, H. Twigg, 2017, Chest.

Activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) increases the expression of prostaglandin E2 receptor subtype EP4. The roles of phosphatidylinositol 3-kinase and CCAAT/enhancer-binding protein beta.

J. Roman, J. Ritzenthaler, B. Wingerd, 2005, The Journal of biological chemistry.

The elevated systemic cytokine levels in HIV patients are not associated with an elevated pulmonary cytokine environment.

R. Fernandez-Botran, J. Ramirez, J. Roman, 2020, Cytokine.

Predisposition for Disrepair in the Aged Lung

M. Rojas, J. Roman, J. Ritzenthaler, 2012, The American journal of the medical sciences.

Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report.

H. Collard, K. Anstrom, F. Martinez, 2014, American journal of respiratory and critical care medicine.

Up-regulation of p 21 Gene Expression by Peroxisome Proliferator-Activated Receptor in Human Lung Carcinoma Cells

P. Fisher, J. Roman, N. Sidell, 2004 .

Nicotine stimulates human lung cancer cell growth by inducing fibronectin expression.

Ying Zheng, J. Roman, J. Ritzenthaler, 2007, American journal of respiratory cell and molecular biology.

Recruitment and retention in academic medicine--what junior faculty and trainees want department chairs to know.

J. Roman, D. Kamen, D. Guidot, 2012, The American journal of the medical sciences.

Epigenetic regulation of EC-SOD expression in aging lung fibroblasts: Role of histone acetylation.

J. Roman, J. Ritzenthaler, I. Zelko, 2017, Free radical biology & medicine.

PPARbeta/delta agonist increases the expression of PGE2 receptor subtype EP4 in human lung carcinoma cells.

J. Roman, J. Ritzenthaler, Shouwei Han, 2009, Methods in molecular biology.

Gastroesophageal Reflux and Microaspiration in Lung Transplant Recipients: The Utility of a Single Esophageal Manometry and pH Probe Monitoring Study.

T. Abell, J. Roman, J. Ritzenthaler, 2020, Transplantation proceedings.

Polyketal microparticles for therapeutic delivery to the lung.

T. Barker, Stephen C. Yang, N. Murthy, 2010, Biomaterials.

COX‐2 inhibitors suppress integrin α5 expression in human lung carcinoma cells through activation of Erk: Involvement of Sp1 and AP‐1 sites

J. Roman, Shouwei Han, 2005, International journal of cancer.

Redox States of Protein Cysteines in Pathways of Protein Turnover and Cytoskeleton Dynamics Are Changed with Aging and Reversed by Slc7a11 Restoration in Mouse Lung Fibroblasts

M. Merchant, A. Gaweda, W. Watson, 2020, Oxidative medicine and cellular longevity.

Distribution of extracellular matrices, matrix receptors, and transforming growth factor-beta 1 in human and experimental lung granulomatous inflammation.

J. Roman, A. Gal, R. Pérez, 1995, The American journal of the medical sciences.

Interleukin-1beta gene transcription in U937 cells is modulated by type I collagen and cytoskeletal integrity via distinct signaling pathways.

J. Roman, J. Ritzenthaler, 2001, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

COX-2 inhibitors suppress lung cancer cell growth by inducing p21 via COX-2 independent signals.

J. Roman, Shouwei Han, 2006, Lung cancer.

Research Needs on Respiratory Health in Migrant and Refugee Populations. An Official American Thoracic Society and European Respiratory Society Workshop Report

J. Ramirez, E. Perez-stable, I. Annesi-Maesano, 2018, Annals of the American Thoracic Society.

Rosiglitazone suppresses human lung carcinoma cell growth through PPARgamma-dependent and PPARgamma-independent signal pathways.

J. Roman, ShouWei Han, Jesse Roman, 2006, Molecular cancer therapeutics.

Acute exacerbations of progressive-fibrosing interstitial lung diseases

J. Huggins, J. Roman, M. Kolb, 2018, European Respiratory Review.

Nicotine and fibronectin expression in lung fibroblasts: implications for tobacco‐related lung tissue remodeling

J. Roman, J. Ritzenthaler, H. Rivera, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Bronchoalveolar Lavage Fluid D Dimer Levels Are Higher and More Prevalent in Black Patients with Pulmonary Sarcoidosis

J. Roman, S. Aguayo, R. Pérez, 2006, Respiration.

Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors.

J. Roman, E. Spindel, D. Hyde, 2012, American journal of respiratory cell and molecular biology.

Patient Registries in Idiopathic Pulmonary Fibrosis

Hyun J. Kim, K. Flaherty, C. Ryerson, 2019, American journal of respiratory and critical care medicine.

Anti-tissue remodeling effects of corticosteroids: fluticasone propionate inhibits fibronectin expression in fibroblasts.

J. Roman, J. Ritzenthaler, H. Rivera, 2005, Chest.

Plasminogen Activator Inhibitor‐1 Is Critical in Alcohol‐Enhanced Acute Lung Injury in Mice

G. Arteel, J. Luyendyk, J. Roman, 2017, American journal of respiratory cell and molecular biology.

Composition of the Sepsis Definitions Task Force.

J. Roman, E. Burnham, 2016, JAMA.

Rosiglitazone, an Agonist of PPARγ, Inhibits Non-Small Cell Carcinoma Cell Proliferation In Part through Activation of Tumor Sclerosis Complex-2

Ying Zheng, J. Roman, Shouwei Han, 2007, PPAR research.

Granulomatous Inflammation and the Lymphatic System-Perhaps a New Target for Intervention in Tuberculosis and Sarcoidosis (Comment on https://doi.org/10.1002/bies.201900086).

J. Roman, R. Pérez, 2019, BioEssays : news and reviews in molecular, cellular and developmental biology.

Management of Idiopathic Pulmonary Fibrosis

J. Roman, Daniel Fioret, Rafael L. Perez, 2011, The American journal of the medical sciences.

Tocilizumab in the Management of COVID-19: A Preliminary Report

J. Jallo, J. Roman, M. Baram, 2020, The American Journal of the Medical Sciences.

An American Thoracic Society/National Heart, Lung, and Blood Institute Workshop Report: Addressing Respiratory Health Equality in the United States

E. Burchard, J. Samet, R. Kittles, 2017, Annals of the American Thoracic Society.

Control of lung epithelial growth by a nicotinic acetylcholine receptor: the other side of the coin.

J. Roman, Michael Koval, 2009, The American journal of pathology.

BRCA1 185delAG Mutation Enhances Interleukin-1β Expression in Ovarian Surface Epithelial Cells

P. Kruk, J. Roman, K. Dobrinski, 2015, BioMed research international.

Ethanol stimulates the expression of fibronectin in lung fibroblasts via kinase-dependent signals that activate CREB.

J. Roman, J. Ritzenthaler, R. Bechara, 2005, American journal of physiology. Lung cellular and molecular physiology.

Peroxisome proliferator-activated receptor-ligands suppress fibronectin gene expression in human lung carcinoma cells : involvement of both CRE and Sp 1

J. Roman, J. Ritzenthaler, H. Rivera, 2005 .

Peroxisome Proliferator-Activated Receptor γ and Lung Cancer Biology

J. Roman, 2008, Journal of Investigative Medicine.

Regulation of serum-induced fibronectin expression by protein kinases, cytoskeletal integrity, and CREB.

J. Roman, J. Ritzenthaler, J. Michaelson, 2002, American journal of physiology. Lung cellular and molecular physiology.

J. Roman, S. Suliman, R. Pérez, 2017, Respiratory medicine case reports.

Enhancing Recruitment and Retention of Minority Populations for Clinical Research in Pulmonary, Critical Care, and Sleep Medicine: An Official American Thoracic Society Research Statement

N. Thakur, J. Celedón, K. Riekert, 2021, American journal of respiratory and critical care medicine.

Acute exacerbations in the INPULSIS trials of nintedanib in idiopathic pulmonary fibrosis

H. Collard, H. Taniguchi, R. D. du Bois, 2017, European Respiratory Journal.

Activated PPARγ Targets Surface and Intracellular Signals That Inhibit the Proliferation of Lung Carcinoma Cells

J. Roman, Shouwei Han, 2008, PPAR research.

Complementing Lung Cancer: How Tumor Cells Co-opt the Host Complement System to Reach Bone.

J. Roman, 2018, American Journal of Respiratory and Critical Care Medicine.

The Integrin Inhibitor Cilengitide and Bleomycin-Induced Pulmonary Fibrosis

J. Roman, J. Ritzenthaler, E. Torres-González, 2020, Lung.

Peripheral blood proteomic profiling of idiopathic pulmonary fibrosis biomarkers in the multicentre IPF-PRO Registry

Hyun J. Kim, I. Noth, M. Strek, 2019, Respiratory Research.

Peroxisome proliferator-activated receptor-gamma ligands inhibit alpha5 integrin gene transcription in non-small cell lung carcinoma cells.

J. Roman, H. Rivera, Shouwei Han, 2005, American journal of respiratory cell and molecular biology.

Role of extracellular matrices, matrix receptors, and cytokines in granulomatous lung inflammation.

J. Roman, G. Staton, R. Pérez, 1993, Chest.

Fibroblasts—Warriors at the Intersection of Wound Healing and Disrepair

J. Roman, 2023, Biomolecules.

Targeting apoptotic signaling pathways in human lung cancer.

S. Han, J. Roman, S W Han, 2010, Current cancer drug targets.

Remodeling of the Extracellular Matrix in the Aging Lung

J. Roman, 2014 .

Matrix metalloproteinase activity in the lung is increased in Hermansky-Pudlak syndrome

J. Roman, R. Summer, B. Gochuico, 2019, Orphanet Journal of Rare Diseases.

The Role of PPARs in Lung Fibrosis

J. Roman, T. Thatcher, P. Sime, 2007, PPAR research.

Prognostic Factors for Hospital Mortality and ICU Admission in Patients With ANCA-Related Pulmonary Vasculitis

J. Roman, A. Gal, F. Holguin, 2008 .

The Role of Peroxisome Proliferator-Activated Receptors in Pulmonary Vascular Disease

J. Roman, C. Hart, R. Sutliff, 2007, PPAR research.

Chronic + binge alcohol exposure promotes inflammation and alters airway mechanics in the lung.

G. Arteel, G. Hoyle, J. Roman, 2019, Alcohol.

Beyond the ICU: Frailty and Post-ICU Disability. Healthcare Use after Acute Respiratory Distress Syndrome and Severe Sepsis.

J. Roman, G. George, Mitchell D Jacobs, 2019, American journal of respiratory and critical care medicine.

Glutamine restores mitochondrial respiration in bleomycin-injured epithelial cells.

J. Roman, R. Summer, Jianxin Sun, 2021, Free radical biology & medicine.

Open and closed models of intensive care unit have different influences on infectious complications in a tertiary care center: A retrospective data analysis.

T. Wiemken, R. Cavallazzi, J. Roman, 2016, American journal of infection control.

Oxidation of extracellular cysteine/cystine redox state in bleomycin-induced lung fibrosis.

Dean P. Jones, M. Rojas, J. Roman, 2009, American journal of physiology. Lung cellular and molecular physiology.

Transforming growth factor beta1 expression and activation is increased in the alcoholic rat lung.

J. Roman, R. Bechara, L. Brown, 2004, American journal of respiratory and critical care medicine.

The Fibrosis Across Organs Symposium: A Roadmap for Future Research Priorities

D. Brenner, K. Brown, L. Richeldi, 2019, The American journal of the medical sciences.

Nicotine stimulates PPARbeta/delta expression in human lung carcinoma cells through activation of PI3K/mTOR and suppression of AP-2alpha.

Ying Zheng, J. Roman, J. Ritzenthaler, 2009, Cancer research.

PPARs: Regulators and Translational Targets in the Lung

J. Roman, P. Sime, V. Rehan, 2012, PPAR research.