A. Knox

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Defective Histone Acetylation Is Responsible for the Diminished Expression of Cyclooxygenase 2 in Idiopathic Pulmonary Fibrosis

W. Coward, Keiria Watts, C. Feghali-Bostwick, 2009, Molecular and Cellular Biology.

Molecular Mechanisms Of Increased Expression Of The Chemokine Monocyte Chemoattractant Protein-1 (MCP-1) In Idiopathic Pulmonary Fibrosis (IPF)

W. Coward, C. Feghali-Bostwick, A. Knox, 2011, ATS 2011.

A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis

W. Coward, C. Feghali-Bostwick, A. Knox, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

cultured on Aligned Electrospun Scaffolds 2

C. Brightling, A. Ghaemmaghami, A. Knox, 2014 .

Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds.

C. Brightling, A. Ghaemmaghami, A. Knox, 2014, American journal of physiology. Lung cellular and molecular physiology.

Guanylyl cyclases, nitric oxide, natriuretic peptides, and airway smooth muscle function.

A. Knox, A. M. Hamad, A. Clayton, 2003, American journal of physiology. Lung cellular and molecular physiology.

Factors iinfluencing tthe ooccurrence oof airway hhyperreactivity iin tthe ggeneral ppopulation: the iimportance oof aatopy aand aairway ccalibre

I. Pavord, S. Weiss, A. Tattersfield, 1994 .

Factors influencing the occurrence of airway hyperreactivity in the general population: the importance of atopy and airway calibre.

I. Pavord, S. Weiss, A. Tattersfield, 1994, The European respiratory journal.

Effect of oral digoxin, topical ouabain and salbutamol on transepithelial nasal potential difference in patients with cystic fibrosis.

A. Conn, S. Lewis, A. Knox, 1995, Clinical science.

Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort

Ioannis Pandis, Charles Auffray, Thomas Sandström, 2015, European Respiratory Journal.

Assessing the burden of respiratory disease in the UK.

A. Morice, P. Corris, A. Knox, 2002, Respiratory medicine.

Investigating NF-κB signaling in lung fibroblasts in 2D and 3D culture systems

J. Haycock, A. Ghaemmaghami, A. Knox, 2015, Respiratory Research.

Guidelines for the management of hospital-acquired pneumonia in the UK: Report of the Working Party on Hospital-Acquired Pneumonia of the British Society for Antimicrobial Chemotherapy

A. Gascoigne, R. Spencer, D. Nathwani, 2008, The Journal of antimicrobial chemotherapy.

Synergistic Inhibition by β2-Agonists and Corticosteroids on Tumor Necrosis Factor- α –Induced Interleukin-8 Release from Cultured Human Airway Smooth-Muscle Cells

A. Knox, L. Pang, 2000 .

Synergistic inhibition by beta(2)-agonists and corticosteroids on tumor necrosis factor-alpha-induced interleukin-8 release from cultured human airway smooth-muscle cells.

A. Knox, L. Pang, 2000, American journal of respiratory cell and molecular biology.

PKCβΙΙ Augments NF-κB-Dependent Transcription at the CCL11 Promoter via p300/CBP-Associated Factor Recruitment and Histone H4 Acetylation1

A. Knox, D. Clarke, A. Sutcliffe, 2008, The Journal of Immunology.

β2-Adrenoceptor Agonists, Like Glucocorticoids, Repress Eotaxin Gene Transcription by Selective Inhibition of Histone H4 Acetylation 1

A. Knox, L. Pang, M. Nie, 2005, The Journal of Immunology.

Histone H 4 Acetylation Transcription by Selective Inhibition of Glucocorticoids , Repress Eotaxin Gene-Adrenoceptor Agonists , Like 2 β

A. Knox, L. Pang, M. Nie, 2005 .

Synthetic responses in airway smooth muscle.

P. Howarth, R. Panettieri, A. Knox, 2004, The Journal of allergy and clinical immunology.

Synthetic functions of airway smooth muscle in asthma.

S. Johnson, A. Knox, Alan J. Knox, 1997, Trends in pharmacological sciences.

Impaired cAMP production in human airway smooth muscle cells by bradykinin: role of cyclooxygenase products.

A. Knox, L. Pang, E. Holland, 1998, American journal of physiology. Lung cellular and molecular physiology.

Once versus three-times daily regimens of tobramycin treatment for pulmonary exacerbations of cystic fibrosis—the TOPIC study: a randomised controlled trial

S. Lewis, A. Knox, D. Stableforth, 2005, The Lancet.

Do long-acting beta2-adrenoceptor agonists enhance the anti-inflammatory effect of glucocorticoids in asthma?

A. Knox, L. Pang, Y. M. Zhu, 2001, The European respiratory journal.

Angiogenesis and vascular endothelial growth factor in COPD

A. Knox, J. Stocks, A. Sutcliffe, 2005, Thorax.

TGF-beta1 stimulates IL-8 release, COX-2 expression, and PGE(2) release in human airway smooth muscle cells.

A. Knox, L. Pang, E. Holland, 2000, American journal of physiology. Lung cellular and molecular physiology.

TGF-β1 stimulates IL-8 release, COX-2 expression, and PGE2release in human airway smooth muscle cells

A. Knox, L. Pang, E. Holland, 2000 .

Abnormal Histone Methylation Is Responsible for Increased Vascular Endothelial Growth Factor 165a Secretion from Airway Smooth Muscle Cells in Asthma

C. Brightling, A. Knox, A. John, 2012, The Journal of Immunology.

from Airway Smooth Muscle Cells in Endothelial Growth Factor 165a Secretion Responsible for Increased Vascular Abnormal Histone Methylation Is

C. Brightling, A. Knox, A. John, 2012 .

Effect of addition of exercise to chest physiotherapy on sputum expectoration and lung function in adults with cystic fibrosis.

A. Knox, D. Baldwin, D. Peckham, 1994, Respiratory medicine.

Acute hydrocortisone myopathy in acute severe asthma.

M. Muers, A. Knox, B. H. Mascie-Taylor, 1986, Thorax.

Loss of epithelial Gq and G11 signaling inhibits TGFβ production but promotes IL-33–mediated macrophage polarization and emphysema

S. Offermanns, A. Knox, R. Jenkins, 2016, Science Signaling.

Accelerated extracellular matrix turnover during exacerbations of COPD

M. Karsdal, A. Knox, Simon R. Johnson, 2015, Respiratory Research.

Regulation of cGMP by soluble and particulate guanylyl cyclases in cultured human airway smooth muscle.

A. Knox, A. M. Hamad, S. Range, 1997, American journal of physiology. Lung cellular and molecular physiology.

The relation between peripheral blood leukocyte counts and respiratory symptoms, atopy, lung function, and airway responsiveness in adults.

J. Stringer, S. Lewis, J. Britton, 2001, Chest.

Forrester, Doug L. and Knox, Alan J. and Smyth, Alan R. and Fogarty, Andrew W. (2013) Measures of body habitus are associated with lung function in adults with cystic fibrosis: a population-based study

A. Fogarty, A. Knox, A. Smyth, 2016 .

Measures of body habitus are associated with lung function in adults with cystic fibrosis: A population-based study☆

A. Fogarty, A. Knox, A. Smyth, 2013, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease

A. Bittner, M. Polkey, I. Adcock, 2015, The Journal of allergy and clinical immunology.

Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD

M. Kobor, P. Nair, A. Knox, 2018, Clinical Epigenetics.

FANTOM5 CAGE profiles of human and mouse samples

Jay W. Shin, Thomas J. Ha, Kelly J. Morris, 2017, Scientific Data.

Future bronchodilator therapy: a bitter pill to swallow?

A. Knox, Rachel L Clifford, R. Clifford, 2012, American journal of physiology. Lung cellular and molecular physiology.

Blanching the airways: steroid effects in asthma

A. Knox, K. Deacon, Rachel L Clifford, 2007, Thorax.

Cytokines upregulate vascular endothelial growth factor secretion by human airway smooth muscle cells: Role of endogenous prostanoids

A. Knox, L. Pang, J. Stocks, 2005, FEBS letters.

This information is current as Airway Smooth Muscle Cells in Asthma Activation by β 5-Mediated TGF-β v α Integrin

Habgood, C. Brightling, D. Sheppard, 2011 .

Transcriptional regulation of monocyte chemotactic protein‐1 release by endothelin‐1 in human airway smooth muscle cells involves NF‐κB and AP‐1

A. Knox, D. Clarke, A. Sutcliffe, 2009, British journal of pharmacology.

Comparison of a step-down dose of once-daily ciclesonide with a continued dose of twice-daily fluticasone propionate in maintaining control of asthma*

A. Knox, C. Gruss, D. Häfner, 2007, Current medical research and opinion.

Cyclooxygenase-2 Expression by Nonsteroidal Anti-inflammatory Drugs in Human Airway Smooth Muscle Cells: Role of Peroxisome Proliferator-Activated Receptors1

A. Knox, L. Pang, L. Corbett, 2003, The Journal of Immunology.

Proliferator-Activated Receptors Smooth Muscle Cells : Role of Peroxisome Anti-inflammatory Drugs in Human Airway Cyclooxygenase-2 Expression by Nonsteroidal

A. Knox, L. Pang, L. Corbett, 2002 .

CCR3 induced‐p42/44 MAPK activation protects against staurosporine induced‐DNA fragmentation but not apoptosis in airway smooth muscle cells

S. Johnson, A. Knox, D. Clements, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Overexpression of cyclooxygenase-2 in non-small cell lung cancer.

C. Clelland, J. Coulson, A. Knox, 2004, Respiratory medicine.

Expression and regulation of immune-modulatory enzyme indoleamine 2,3-dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activation

A. Ghaemmaghami, H. Sewell, A. Knox, 2016, Oncotarget.

CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BET

C. Brightling, A. Knox, A. Tatler, 2015, American journal of physiology. Lung cellular and molecular physiology.

Effect of bradykinin, TGF-β1, IL-1β, and hypoxia on COX-2 expression in pulmonary artery smooth muscle cells

A. Knox, L. Pang, J. Stocks, 2002 .

Interleukin-1&bgr;, Transforming Growth Factor-&bgr;1, and Bradykinin Attenuate Cyclic AMP Production by Human Pulmonary Artery Smooth Muscle Cells in Response to Prostacyclin Analogues and Prostaglandin E2 by Cyclooxygenase-2 Induction and Downregulation of Adenylyl Cyclase Isoforms 1, 2, and 4

A. Knox, A. Clayton, D. Bradbury, 2004 .

IL-1beta, BK, and TGF-beta1 attenuate PGI2-mediated cAMP formation in human pulmonary artery smooth muscle cells by multiple mechanisms involving p38 MAP kinase and PKA.

A. Knox, D. Clarke, A. Clayton, 2008, American journal of physiology. Lung cellular and molecular physiology.

Protein kinase C‐ε mediates bradykinin‐induced cyclooxygenase‐2 expression in human airway smooth muscle cells

S. Gray, R. Donnelly, A. Knox, 2002 .

E(cid:128)ect of interleukin-1 (cid:98) , tumour necrosis factor- (cid:97) and interferon- (cid:103) on the induction of cyclo-oxygenase-2 in cultured human airway smooth muscle cells

A. Knox, L. Pang, 1997 .

PINX1 and TERT Are Required for TNF-α–Induced Airway Smooth Muscle Chemokine Gene Expression

A. Knox, K. Deacon, 2018, The Journal of Immunology.

Use of a three-dimensional cell culture model to study airway smooth muscle-mast cell interactions in airway remodeling Claudia

A. Knox, Simon R. Johnson, C. Ceresa, 2009 .

Regulation of TNF‐α‐induced eotaxin release from cultured human airway smooth muscle cells by β2‐agonists and corticosteroids

A. Knox, L. Pang, 2001 .

PGE2 release by bradykinin in human airway smooth muscle cells: involvement of cyclooxygenase-2 induction.

A. Knox, L. Pang, 1997, American journal of physiology. Lung cellular and molecular physiology.

Effect of interleukin-1 beta, tumour necrosis factor-alpha and interferon-gamma on the induction of cyclo-oxygenase-2 in cultured human airway smooth muscle cells.

A. Knox, L. Pang, 1997, British journal of pharmacology.

Ciclesonide inhibits TNFα- and IL-1β-induced monocyte chemotactic protein-1 (MCP-1/CCL2) secretion from human airway smooth muscle cells

A. Knox, K. Deacon, Rachel L Clifford, 2012, American journal of physiology. Lung cellular and molecular physiology.

Bradykinin stimulates IL-8 production in cultured human airway smooth muscle cells: role of cyclooxygenase products.

A. Knox, L. Pang, Alan J. Knox, 1998, Journal of immunology.

Mast Cell β-Tryptase Selectively Cleaves Eotaxin and RANTES and Abrogates Their Eosinophil Chemotactic Activities1

A. Knox, L. Pang, A. Sutcliffe, 2006, The Journal of Immunology.

Airway re-modelling in asthma: role of airway smooth muscle.

A. Knox, 1994, Clinical science.

Role of cyclo‐oxygenase‐2 induction in interleukin‐1β induced attenuation of cultured human airway smooth muscle cell cyclic AMP generation in response to isoprenaline

A. Knox, L. Pang, E. Holland, 1998, British journal of pharmacology.

Production of PGE2 by bovine cultured airway smooth muscle cells and its inhibition by cyclo‐oxygenase inhibitors

I. Pavord, A. Knox, J. Bennett, 1994, British journal of pharmacology.

Pharmacokinetic Optimisation of Inhaled Steroid Therapy in Asthma

I. Pavord, A. Knox, 1993, Clinical pharmacokinetics.

Matrix metalloproteinase expression and activity in human airway smooth muscle cells

S. Watson, A. Knox, Simon R. Johnson, 2004, British journal of pharmacology.

Time course of change in bronchial reactivity with an inhaled corticosteroid in asthma.

A. Tattersfield, A. Knox, A. Wisniewski, 1991, The American review of respiratory disease.

Regulation of cGMP by soluble and particulate guanylyl cyclases in cultured human airway smooth muscle

A. Knox, A. M. Hamad, S. Range, 1997 .

Selectivity of cyclo-oxygenase inhibitors in human pulmonary epithelial and smooth muscle cells.

A. Knox, L. Pang, S. Range, 2000, The European respiratory journal.

Effect of diuretics on allergen-induced contractions of passively sensitized human bronchi in vitro.

I. Pavord, A. Tattersfield, A. Knox, 1995, American journal of respiratory and critical care medicine.

Cross refractoriness between sodium metabisulphite and exercise induced asthma.

I. Pavord, A. Tattersfield, A. Knox, 1994, Thorax.

ALUNG November 21/5

A. Knox, Simon R. Johnson, A. M. Hamad, 1999 .

Mast cell migration to airway smooth muscle in asthma. Can we Gro(w) something to block the attraction?

A. Knox, A. Lagan, A. Lagan, 2014, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Human Airway Smooth Muscle Cells from Asthmatic Individuals Have CXCL8 Hypersecretion Due to Increased NF-κB p65, C/EBPβ, and RNA Polymerase II Binding to the CXCL8 Promoter1

C. Brightling, A. Knox, L. Pang, 2009, The Journal of Immunology.

Epigenetics of Asthma

A. Knox, K. Kaczmarek, Rachel L Clifford, 2021 .

Epigenetic Changes in Airway Smooth Muscle as a Driver of Airway Inflammation and Remodeling in Asthma

A. Knox, K. Kaczmarek, Rachel L Clifford, 2019, Chest.

Differential regulation of chemokine expression by peroxisome proliferator-activated receptor gamma agonists: interactions with glucocorticoids and beta2-agonists.

A. Knox, L. Pang, L. Corbett, 2005, The Journal of biological chemistry.

Human airway smooth muscle cells secrete amphiregulin via bradykinin/COX-2/PGE2, inducing COX-2, CXCL8, and VEGF expression in airway epithelial cells.

A. Knox, K. Deacon, 2015, American journal of physiology. Lung cellular and molecular physiology.

Tryptase activates TGFbeta in human airway smooth muscle cells via direct proteolysis.

A. Knox, L. Pang, G. Jenkins, 2008, Biochemical and biophysical research communications.

maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds. American

A. Ghaemmaghami, A. Knox, F. Rose, 2017 .

Airway smooth muscle

A. Tattersfield, A. Knox, 1994 .

Effect of inhaled prostaglandin E2 on bronchial reactivity to sodium metabisulphite and methacholine in patients with asthma.

I. Pavord, A. Tattersfield, A. Knox, 1991, Thorax.

Glutamine supplementation in cystic fibrosis: A randomized placebo‐controlled trial

I. Pavord, A. Fogarty, A. Knox, 2016, Pediatric pulmonology.

Prostanoids as anti-inflammatory therapy: separating the good from the bad

A. Knox, 2015, Thorax.

TGF- b 1 stimulates IL-8 release, COX-2 expression, and PGE 2 release in human airway smooth muscle cells

A. Knox, L. Pang, E. Holland, 2000 .

Impaired cAMP production in human airway smooth muscle cells by bradykinin: role of cyclooxygenase products.

A. Knox, L. Pang, E. Holland, 1998, The American journal of physiology.

PRODUCTION OF PGE(2) BY CULTURED AIRWAY SMOOTH-MUSCLE CELLS AND ITS INHIBITION BY PROSTAGLANDIN SYNTHETASE INHIBITORS

Sanjay V. Patel, I. Pavord, A. Knox, 1993 .

The effect of amiloride on the airway response to metabisulphite in asthma: a negative report.

I. Pavord, A. Knox, D. Baldwin, 1992, The European respiratory journal.

Effect of frusemide on airway smooth muscle contractility in vitro.

A. Knox, P. Ajao, 1990, Thorax.

Sodium/Potassium/Chloride Co-Transport

A. Knox, 1995 .

Comparison of three inhaled non-steroidal anti-inflammatory drugs on the airway response to sodium metabisulphite and adenosine 5'-monophosphate challenge in asthma.

I. Pavord, A. Tattersfield, A. Knox, 1996, Thorax.

The effect of inhaled heparin on bronchial reactivity to sodium metabisulphite and methacholine in patients with asthma.

I. Pavord, A. Knox, P. Wilding, 1996, The European respiratory journal.

A comparison of the effects of inhaled furosemide and ethacrynic acid on sodium-metabisulfite-induced bronchoconstriction in subjects with asthma.

I. Pavord, A. Tattersfield, A. Knox, 1995, American journal of respiratory and critical care medicine.

Effect of sodium-transport inhibitors on bronchial reactivity in vivo.

A. Tattersfield, J. Britton, A. Knox, 1990, Clinical science.

Effect of sodium-transport inhibitors on airway smooth muscle contractility in vitro.

A. Tattersfield, J. Britton, A. Knox, 1990, Clinical science.

The effect of the nitric oxide synthase inhibitor, L-NMMA, on sodium metabisulphite-induced bronchoconstriction and refractoriness in asthma.

A. Knox, A. M. Hamad, S. Range, 1999, The European respiratory journal.

Collagen I and thrombin activate MMP-2 by MMP-14-dependent and -independent pathways: implications for airway smooth muscle migration.

A. Knox, Simon R. Johnson, A. Freyer, 2007, American journal of physiology. Lung cellular and molecular physiology.

Autocrine production of matrix metalloproteinase-2 is required for human airway smooth muscle proliferation.

S. Johnson, A. Knox, 1999, The American journal of physiology.

The differential effects of azithromycin on the airway epithelium in vitro and in vivo

I. Sayers, D. Shaw, A. Knox, 2016, Physiological reports.

implications for airway smooth muscle migration MMP-14-dependent and -independent pathways: Collagen I and thrombin activate MMP-2 by

A. Knox, Simon R. Johnson, A. Freyer, 2016 .

Desensitization of guanylyl cyclases in cultured human airway smooth-muscle cells.

A. Knox, A. M. Hamad, S. Range, 1999, American journal of respiratory cell and molecular biology.

Cells: Role of Cyclooxygenase Products Cultured Human Airway Smooth Muscle Bradykinin Stimulates IL-8 Production in

A. Knox, L. Pang, 1998 .

Circulating Antibody and Memory B-Cell Responses to C. difficile Toxins A and B in Patients with C. difficile-Associated Diarrhoea, Inflammatory Bowel Disease and Cystic Fibrosis

H. Sewell, A. Knox, T. Monaghan, 2013, PloS one.

2-Alkyl-4-quinolone quorum sensing molecules are biomarkers for culture-independent Pseudomonas aeruginosa burden in adults with cystic fibrosis.

D. Barrett, A. Fogarty, A. Knox, 2021, Journal of medical microbiology.

Modification of bronchial reactivity by physiological concentrations of plasma epinephrine.

I. Macdonald, A. Tattersfield, A. Knox, 1992, Journal of applied physiology.

How prevalent is aspirin induced asthma?

A. Knox, 2002, Thorax.

Regulation of TNF-alpha-induced eotaxin release from cultured human airway smooth muscle cells by beta2-agonists and corticosteroids.

A. Knox, L. Pang, Alan J. Knox, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Treatment of pulmonary exacerbations of cystic fibrosis leads to improved antioxidant status.

F. Kelly, A. Knox, S. Range, 1999, The European respiratory journal.

Effect of antibiotic treatment on inflammatory markers and lung function in cystic fibrosis patients with Pseudomonas cepacia.

A. Knox, B. Lobo, H. Humphreys, 1994, Thorax.

Airway epithelial cell isolation techniques affect DNA methylation profiles with consequences for analysis of asthma related perturbations to DNA methylation

M. Kobor, A. Knox, Simon R. Johnson, 2019, Scientific Reports.

A comparison of the Yan and a dosimeter method for methacholine challenge in experienced and inexperienced subjects.

A. Tattersfield, A. Knox, A. Wisniewski, 1991, The European respiratory journal.

Airway smooth muscle: telling the eosinophil how to behave

A. Knox, D. Forrester, 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Cyclooxygenase-2 Induction by Bradykinin in Human Pulmonary Artery Smooth Muscle Cells Is Mediated by the Cyclic AMP Response Element through a Novel Autocrine Loop Involving Endogenous Prostaglandin E2, E-prostanoid 2 (EP2), and EP4 Receptors*

A. Knox, R. Newton, Yong-ming Zhu, 2003, Journal of Biological Chemistry.

Transcriptional Regulation of Interleukin (IL)-8 by Bradykinin in Human Airway Smooth Muscle Cells Involves Prostanoid-dependent Activation of AP-1 and Nuclear Factor (NF)-IL-6 and Prostanoid-independent Activation of NF-κB*

A. Knox, L. Pang, Yong-ming Zhu, 2003, Journal of Biological Chemistry.

Recruitment of women into trials

A. Knox, A. Smyth, T. Stephenson, 2002, The Lancet.

Simple exercise testing.

M. Muers, A. Knox, 1990, Respiratory medicine.

Edinburgh Research Explorer Reduced Ets domain-containing protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin v6 Expression

P. Weinreb, S. Violette, S. Alberti, 2018 .

Reduction in colposcopy workload and associated clinical activity following HPV catch-up vaccination programme in Scotland: an ecological study

P. Weinreb, S. Violette, S. Alberti, 2016 .

Dietary magnesium, lung function, wheezing, and airway hyper-reactivity in a random adult population sample

I. Pavord, A. Tattersfield, S. Lewis, 1994, The Lancet.

DIETARY-SODIUM AND AIRWAY HYPERREACTIVITY IN A GENERAL-POPULATION SAMPLE

I. Pavord, A. Tattersfield, J. Britton, 1993 .

THE EFFECTS OF DIETARY ANTIOXIDANTS ON LUNG-FUNCTION IN THE GENERAL-POPULATION

I. Pavord, A. Tattersfield, S. Lewis, 1993 .

Regulation of guanosine 3′:5′‐cyclic monophosphate in ovine tracheal epithelial cells

A. Knox, S. Range, E. Holland, 1997, British journal of pharmacology.

Glucocorticoid and β-adrenoceptor agonist interactions in asthma

A. Knox, L. Pang, 2002, The Lancet.

Interplay between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis

O. Brand, W. Coward, A. Knox, 2017, American journal of respiratory cell and molecular biology.

EZH 2 and G 9 a regulate CXCL 10 repression in IPF 1 Interplay between EZH 2 and G 9 a Regulates CXCL 10 Gene Repression in Idiopathic Pulmonary Fibrosis

O. Brand, W. Coward, A. Knox, 2017 .

Efficacy, tolerance, and pharmacokinetics of once daily tobramycin for pseudomonas exacerbations in cystic fibrosis

A. Knox, D. Baldwin, A. Smyth, 1999, Archives of disease in childhood.

Camptothecin-induced apoptosis in non-small cell lung cancer is independent of cyclooxygenase expression

P. Navas, A. Knox, G. Brea-Calvo, 2003, Apoptosis.

Effect of oral lithium on bronchial reactivity in asthma.

I. Hall, A. Tattersfield, A. Knox, 1992, Clinical science.

Vitamin D – a new treatment for airway remodelling in asthma?

A. Knox, Rachel L Clifford, R. Clifford, 2009, British journal of pharmacology.

sTREM‐1 is elevated in cystic fibrosis and correlates with proteases

A. Fogarty, A. Knox, H. Barr, 2017, Pediatric pulmonology.

Autocrine production of matrix metalloproteinase-2 is required for human airway smooth muscle proliferation.

A. Knox, Simon R. Johnson, S. Johnson, 1999, American journal of physiology. Lung cellular and molecular physiology.

The effect of inhaled ouabain on bronchial reactivity to histamine in man.

A. Tattersfield, J. Britton, A. Knox, 1988, British journal of clinical pharmacology.

Airway smooth muscle relaxation.

A. Tattersfield, A. Knox, 1995, Thorax.

PI 3‐kinase and MAP kinase regulate bradykinin induced prostaglandin E2 release in human pulmonary artery by modulating COX‐2 activity

A. Knox, D. Bradbury, L. Corbett, 2004, FEBS letters.

from Airway Smooth Muscle Cells in Endothelial Growth Factor 165a Secretion Responsible for Increased Vascular Abnormal Histone Methylation Is

C. Brightling, A. Knox, A. John, 2012 .

Weight gain during acute treatment of an initial pulmonary exacerbation is associated with a longer interval to the next exacerbation in adults with cystic fibrosis

D. Barrett, A. Fogarty, A. Knox, 2017, ERJ Open Research.

The pharmacokinetics and toxicity of morning vs. evening tobramycin dosing for pulmonary exacerbations of cystic fibrosis: A randomised comparison

A. Knox, A. Watson, A. Smyth, 2016, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Beta-tryptase regulates IL-8 expression in airway smooth muscle cells by a PAR-2-independent mechanism.

A. Knox, L. Pang, A. Tatler, 2008, American journal of respiratory cell and molecular biology.

Screening for cystic fibrosis

Z. Miedzybrodzka, N. Haites, J. Britton, 1991, The Lancet.

Pharmacological treatment of the biochemical defect in cystic fibrosis airways.

A. Knox, H. C. Rodgers, 2001, The European respiratory journal.

Respiratory disease in pregnancy

A. Knox, D. Petkova, S. Johnson, 1999 .

Questionnaire survey of male infertility in cystic fibrosis.

A. Knox, D. Baldwin, H. C. Rodgers, 2000, Respiratory medicine.

Endothelin-1 (ET-1) Increases the Expression of Remodeling Genes in Vascular Smooth Muscle through Linked Calcium and cAMP Pathways

A. Knox, K. Deacon, 2010, The Journal of Biological Chemistry.

Lysophosphatidic Acid Induces (cid:1) v (cid:2) 6 Integrin-Mediated TGF- (cid:2) Activation via the LPA2 Receptor and the Small G Protein G (cid:1) q

P. Weinreb, S. Violette, D. Sheppard, 2009 .

Circulating levels of IgG1 and IgG4 Anti‐IgE antibodies and asthma severity

A. Knox, F. Shakib, S. J. Smith, 1994, Allergy.

Production of PGE2 by bovine cultured airway smooth muscle cells: regulation by cAMP.

I. Pavord, A. Knox, F. Delamere, 1995, Journal of applied physiology.

Tackling ACE inhibitor cough

A. Knox, L. Pang, 1997, The Lancet.

Vascular Endothelial Growth Factor Induction by Prostaglandin E2 in Human Airway Smooth Muscle Cells Is Mediated by E Prostanoid EP2/EP4 Receptors and SP-1 Transcription Factor Binding Sites*

C. Seedhouse, A. Knox, J. Stocks, 2005, Journal of Biological Chemistry.

REBOUND INCREASE IN BRONCHIAL RESPONSIVENESS AFTER TREATMENT WITH INHALED TERBUTALINE

A. Tattersfield, J. Britton, A. Knox, 1988, The Lancet.

Combining inhaled glucocorticoids and long acting β2‐adrenoceptor agonists in asthma and COPD

A. Knox, K. Mortimer, 2008, British Journal of Pharmacology.

TNFα and IFNγ Synergistically Enhance Transcriptional Activation of CXCL10 in Human Airway Smooth Muscle Cells via STAT-1, NF-κB, and the Transcriptional Coactivator CREB-binding Protein

M. Belvisi, D. Proud, A. Knox, 2010, The Journal of Biological Chemistry.

Muscling into cystic fibrosis airways

A. Knox, A. Sutcliffe, 2005, Thorax.

rhDNase in cystic fibrosis.

A. Knox, S. Range, 1995, Thorax.

Na+ in cystic fibrosis: is it important?

A. Knox, D. Peckham, 1995, Trends in pharmacological sciences.

Coward, William R. and Feghali-Bostwick, Carol A. and Jenkins, Gisli and Knox, Alan J. and Pang, Linhua (2014) A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis

C. Feghali-Bostwick, A. Knox, L. Pang, 2016 .

A central role for G 9 a and EZH 2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis

W. Coward, C. Feghali-Bostwick, A. Knox, 2014 .

Targeting remodeling in respiratory inflammation.

A. Knox, L. Pang, Y. M. Zhu, 2000, Current opinion in investigational drugs.

The effect of inhibitors of Na/H exchange and Na/Ca exchange on airway smooth muscle contractility.

A. Knox, P. Ajao, 1994, Pulmonary pharmacology.

Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression*

A. Nordheim, P. Weinreb, S. Violette, 2016, The Journal of Biological Chemistry.

Novel Regulation of Vascular Endothelial Growth Factor-A (VEGF-A) by Transforming Growth Factor β1

A. Knox, K. Deacon, Rachel L Clifford, 2008, Journal of Biological Chemistry.

A study of a single high potency multivitamin preparation in the management of cystic fibrosis

A. Knox, A. Smyth, J. Polnay, 1998 .

Molecular characterization of the human airway smooth muscle Na+/Ca2+ exchanger.

A. Knox, A. Pitt, 1996, American journal of respiratory cell and molecular biology.

Vascular Endothelial Growth Factor Induction by Prostaglandin E2 in Human Airway Smooth Muscle Cells Is Mediated by E Prostanoid EP2/EP4 Receptors and SP-1 Transcription Factor Binding Sites*

C. Seedhouse, A. Knox, J. Stocks, 2005, Journal of Biological Chemistry.

Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis.

A. Fogarty, A. Knox, E. Nash, 2021, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

difficile Toxins A and B in Patients with C. difficile - Associat ed Diarrhoe a, Inflamma tory Bowel Disease and Cystic Fibrosis

A. Knox, T. Monaghan, Y. Mahida, 2013 .

Effect of bradykinin, TGF-beta1, IL-1beta, and hypoxia on COX-2 expression in pulmonary artery smooth muscle cells.

A. Knox, L. Pang, J. Stocks, 2002, American journal of physiology. Lung cellular and molecular physiology.

The effect of topical benzamil and amiloride on nasal potential difference in cystic fibrosis.

A. Knox, H. C. Rodgers, 1999, The European respiratory journal.

Na+/K+ ATPase in lower airway epithelium from cystic fibrosis and non-cystic-fibrosis lung.

A. Knox, D. Peckham, S. Range, 1997, Biochemical and biophysical research communications.

Population pharmacokinetics of tobramycin administered thrice daily and once daily in children and adults with cystic fibrosis.

A. Knox, A. Smyth, D. Touw, 2007, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Is Burkholderia (Pseudomonas) cepacia disseminated from cystic fibrosis patients during physiotherapy?

H. Humphreys, A. Knox, D. Peckham, 1996, The Journal of hospital infection.

Improving prevention systems in primary care practices: the Health Education and Research Trial (HEART)

L. Solberg, P. McBride, A. Knox, 2000, The Journal of family practice.

Direct detection of N-acylhomoserine lactones in cystic fibrosis sputum.

Miguel Cámara, P. Williams, A. Knox, 2002, FEMS microbiology letters.

A promoter-level mammalian expression atlas

Cesare Furlanello, Finn Drabløs, Carsten O. Daub, 2015 .

Effect of interleukin‐1β, tumour necrosis factor‐α and interferon‐γ on the induction of cyclo‐oxygenase‐2 in cultured human airway smooth muscle cells

A. Knox, L. Pang, 1997 .

Absence of Cochleotoxicity Measured by Standard and High-Frequency Pure Tone Audiometry in a Trial of Once- versus Three-Times-Daily Tobramycin in Cystic Fibrosis Patients

S. Lewis, A. Knox, D. Stableforth, 2006, Antimicrobial Agents and Chemotherapy.

Aminoglycoside prescribing and surveillance in cystic fibrosis.

A. Knox, A. Smyth, M. Mulheran, 2003, American journal of respiratory and critical care medicine.

PGE2 release by bradykinin in human airway smooth muscle cells: involvement of cyclooxygenase-2 induction.

A. Knox, L. Pang, 1997, The American journal of physiology.

Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Martin S. Taylor, Jay W. Shin, Thomas J. Ha, 2021, Nature Communications.

Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q).

P. Weinreb, S. Violette, D. Sheppard, 2009, The American journal of pathology.

Transcriptional regulation of inflammatory genes associated with severe asthma.

W. Coward, A. Knox, A. John, 2011, Current pharmaceutical design.

Transcriptional Regulation of Cyclooxygenase 2 by Bradykinin and Interleukin-1β in Human Airway Smooth Muscle Cells: Involvement of Different Promoter Elements, Transcription Factors, and Histone H4 Acetylation

A. Knox, L. Pang, H. Inoue, 2003, Molecular and Cellular Biology.

Inhibition of polyadenylation reduces inflammatory gene induction.

A. Knox, L. Pang, H. Meijer, 2012, RNA.

Cyclooxygenase (COX) inhibitors induce apoptosis in non-small cell lung cancer through cyclooxygenase independent pathways.

A. Knox, L. Pang, J. Sánchez-Alcázar, 2003, Lung cancer.

Immunocompetent 3D Model of Human Upper Airway for Disease Modeling and In Vitro Drug Evaluation

John W. Haycock, Amir M. Ghaemmaghami, Alan Knox, 2014, Molecular pharmaceutics.

TWIST1 DNA methylation is a cell marker of airway and parenchymal lung fibroblasts that are differentially methylated in asthma

M. Obeidat, M. Kobor, S. May, 2020, Clinical epigenetics.

Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: A longitudinal study

D. Barrett, A. Fogarty, A. Knox, 2017, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Arthropathy in cystic fibrosis.

S. Johnson, A. Knox, S. Johnson, 1994, Respiratory medicine.

Expression of prostaglandin E synthases in periodontitis immunolocalization and cellular regulation.

G. Nilsson, P. Jakobsson, A. Knox, 2011, The American journal of pathology.

Integrin αvβ5-Mediated TGF-β Activation by Airway Smooth Muscle Cells in Asthma

C. Brightling, D. Sheppard, A. Knox, 2011, The Journal of Immunology.

Mechanisms mediating the antiproliferative effects of nitric oxide in cultured human airway smooth muscle cells

A. Knox, A. M. Hamad, 2001, FEBS letters.

Resolution of superior vena cava obstruction following thrombolytic therapy in a patient with cystic fibrosis and a long-term indwelling catheter.

A. Manhire, A. Knox, D. Peckham, 1994, Respiratory medicine.

CCAAT/Enhancer-binding Protein and Activator Protein-1 Transcription Factors Regulate the Expression of Interleukin-8 through the Mitogen-activated Protein Kinase Pathways in Response to Mechanical Stretch of Human Airway Smooth Muscle Cells*

Ashok Kumar, A. Boriek, A. Knox, 2003, Journal of Biological Chemistry.

Lack of concordance in the use and monitoring of intravenous aminoglycosides in UK cystic fibrosis centers

A. Knox, A. Smyth, M. Mulheran, 2002, Pediatric pulmonology.

Garlic as an inhibitor of Pseudomonas aeruginosa quorum sensing in cystic fibrosis—a pilot randomized controlled trial

D. Barrett, C. Ortori, A. Knox, 2010, Pediatric pulmonology.

Novel regulation of vascular endothelial growth factor-A (VEGF-A) by transforming growth factor (beta)1: requirement for Smads, (beta)-CATENIN, AND GSK3(beta).

A. Knox, K. Deacon, Rachel L. Clifford, 2008, The Journal of biological chemistry.

TNFα and IFNγ synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-κB, and the transcriptional coactivator CREB-binding protein.

M. Belvisi, D. Proud, A. Knox, 2010, The Journal of biological chemistry.

Human airway smooth muscle cells secrete vascular endothelial growth factor: up‐regulation by bradykinin via a protein kinase C and prostanoid‐dependent mechanism

A. Knox, L. Pang, J. Stocks, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Differential Regulation of Chemokine Expression by Peroxisome Proliferator-activated Receptor γ Agonists

A. Knox, L. Pang, L. Corbett, 2005, Journal of Biological Chemistry.

Dietary antioxidant vitamin intake and lung function in the general population.

I. Pavord, A. Tattersfield, S. Lewis, 1995, American journal of respiratory and critical care medicine.

Reproducibility of walking test results in chronic obstructive airways disease.

M. Muers, A. Knox, J. Morrison, 1988, Thorax.

Prenatal nutrition and asthma : hope or hype ?

A. Knox, 2008 .

Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial

J. Cockcroft, J. Thornton, T. McKeever, 2015, International journal of chronic obstructive pulmonary disease.

Search for strongly deformed structures and observation of multiple nucleon alignments inW174

D. Hartley, A. Knox, M. Carpenter, 2008 .

COX-2: a link between airway inflammation and disordered chloride secretion in cystic fibrosis?

A. Knox, A. Clayton, 2006, Thorax.

A comparison of three measures of the response to inhaled methacholine.

A. Tattersfield, J. Britton, A. Knox, 1989, The European respiratory journal.

Dietary sodium intake and the risk of airway hyperreactivity in a random adult population.

A. Tattersfield, J. Britton, A. Knox, 1994, Thorax.

Salt and asthma.

A. Knox, 1993, BMJ.

hyperreactivity in a random adult population . Dietary sodium intake and the risk of airway

I. Pavord, A. Tattersfield, J. Britton, 2022 .

Airborne dissemination of Burkholderia (Pseudomonas) cepacia from adult patients with cystic fibrosis.

A. Knox, H. Humphreys, D. Peckham, 1994, Thorax.

Respiratory diseases in pregnancy c 4 Series

A. Knox, F. Edenborough, 2001 .

Antiproliferative effects of NO and ANP in cultured human airway smooth muscle.

A. Knox, A. M. Hamad, S. Johnson, 1999, American journal of physiology. Lung cellular and molecular physiology.

Intravenous antibiotic therapy in cystic fibrosis: in hospital or at home?

A. Knox, D. Peckham, 1993, Respiratory medicine.

Elevated SP-1 Transcription Factor Expression and Activity Drives Basal and Hypoxia-induced Vascular Endothelial Growth Factor (VEGF) Expression in Non-Small Cell Lung Cancer

S. Watson, A. Knox, R. Kumari, 2012, The Journal of Biological Chemistry.

Suberanilohydroxamic acid prevents TGF-β1-induced COX-2 repression in human lung fibroblasts post-transcriptionally by TIA-1 downregulation

O. Brand, A. Knox, L. Pang, 2018, Biochimica et biophysica acta. Gene regulatory mechanisms.

Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis

Miguel Cámara, Alan J. Knox, Edward F. Nash, 2015, European Respiratory Journal.

Clinical significance of Pseudomonas aeruginosa 2-alkyl-4-quinolone quorum-sensing signal molecules for long-term outcomes in adults with cystic fibrosis.

D. Barrett, A. Fogarty, A. Knox, 2019, Journal of medical microbiology.

Use of a three-dimensional cell culture model to study airway smooth muscle-mast cell interactions in airway remodeling.

A. Knox, Claudia C Ceresa, Alan J Knox, 2009, American journal of physiology. Lung cellular and molecular physiology.

Reactive oxygen species mediate the down-regulation of mitochondrial transcripts and proteins by tumour necrosis factor-alpha in L929 cells.

P. Navas, B. Bornstein, J. Arenas, 2003, The Biochemical journal.

A novel electrospun biphasic scaffold provides optimal three-dimensional topography for in vitro co-culture of airway epithelial and fibroblast cells

C. Brightling, A. Ghaemmaghami, A. Knox, 2014, Biofabrication.

Levels of circulating MMP-7 degraded elastin are elevated in pulmonary disorders.

M. Karsdal, B. Svensson, P. Hägglund, 2015, Clinical biochemistry.

Reactive oxygen species mediate the down-regulation of mitochondrial transcripts and proteins by tumour necrosis factor-α in L 929 cells

B. Bornstein, A. Knox, L. De, 2022 .

Aspirin-Induced Asthma

A. Knox, A. M. Hamad, A. Sutcliffe, 2012, Drugs.

Paf-Induced Platelet Aggregation in Whole Blood and the Effect of Administering Bn52063 to Man

A. Tattersfield, A. Knox, S. Heptinstall, 1987 .

Evaluation of the PPAR-γ Agonist Pioglitazone in Mild Asthma: A Double-Blind Randomized Controlled Trial

D. Shaw, A. Knox, L. Pang, 2016, PloS one.

Aspirin and asthma: barking up the right tree?

A. Knox, A. Clayton, D. Forrester, 2008, Thorax.

Comparison of the effects of salbutamol and adrenaline on airway smooth muscle contractility in vitro and on bronchial reactivity in vivo.

A. Knox, D. Baldwin, I. Pavord, 1994, Thorax.

Adapting the Electrospinning Process to Provide Three Unique Environments for a Tri-layered In Vitro Model of the Airway Wall

C. Brightling, A. Ghaemmaghami, A. Knox, 2015, Journal of visualized experiments : JoVE.

Once‐daily tobramycin monotherapy in cystic fibrosis

Kelvin H-V Tan, Pauline Hyman-Taylor, Mike Mulheran, 2002, Pediatric pulmonology.

Role of Rho‐Associated Coiled‐Coil Forming Kinase Isoforms in Regulation of Stiffness‐Induced Myofibroblast Differentiation in Lung Fibrosis

A. Khademhosseini, K. Yue, A. Ghaemmaghami, 2017, American journal of respiratory cell and molecular biology.

Role of ROCK Isoforms in Regulation of Stiffness Induced Myofibroblast Differentiation in Lung Fibrosis

A. Khademhosseini, K. Yue, Byung‐Hyun Cha, 2017 .

Reduced expression of cyclooxygenase (COX) in idiopathic pulmonary fibrosis and sarcoidosis

C. Clelland, A. Knox, J. Ronan, 2003, Histopathology.

INFLUENCE OF INHALED TERBUTALINE ON BRONCHIAL RESPONSIVENESS

A. Tattersfield, J. Britton, A. Knox, 1988, The Lancet.

Epigenetic dysregulation of interleukin 8 (CXCL8) hypersecretion in cystic fibrosis airway epithelial cells.

A. Knox, A. Poghosyan, J. Patel, 2016, Biochemical and biophysical research communications.

Aspirin-induced asthma: clinical aspects, pathogenesis and management.

A. Knox, A. M. Hamad, A. Sutcliffe, 2004, Drugs.

Interleukin-1beta differentially regulates beta2 adrenoreceptor and prostaglandin E2-mediated cAMP accumulation and chloride efflux from Calu-3 bronchial epithelial cells. Role of receptor changes, adenylyl cyclase, cyclo-oxygenase 2, and protein kinase A.

A. Knox, L. Pang, A. Clayton, 2005, The Journal of biological chemistry.

Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Thomas J. Ha, L. K. Nielsen, Kelly J. Hitchens, 2021 .

Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Thomas J. Ha, L. K. Nielsen, Kelly J. Hitchens, 2021 .

Bradykinin increases IL-8 generation in airway epithelial cells via COX-2-derived prostanoids.

A. Knox, L. Pang, S. Range, 2002, American journal of physiology. Lung cellular and molecular physiology.

Matrix metalloproteinases -8 and -9 in the Airways, Blood and Urine During Exacerbations of COPD

A. Knox, C. Bolton, D. Forrester, 2016, COPD.

Electrospun gelatin-based scaffolds as a novel 3D platform to study the function of contractile smooth muscle cells in vitro

D. Player, N. R. Martin, A. Knox, 2018, Biomedical Physics & Engineering Express.

Laparoscopic cholecystectomy in patients with cystic fibrosis.

A. Knox, D. Baldwin, T. Balfour, 1993, Respiratory Medicine.

Laparoscopic cholecystectomy fibrosis in patients with cystic

A. Knox, D. Baldwin, T. Balfour, 1993 .

Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Thomas J. Ha, L. K. Nielsen, Kelly J. Hitchens, 2022 .

FANTOM5 CAGE profiles of human and mouse samples.

Jay W. Shin, Thomas J. Ha, Kelly J. Morris, 2017, Scientific data.

Once versus three-times daily regimens of tobramycin treatment for pulmonary exacerbations of cystic fibrosis—the TOPIC study: a randomised controlled trial

S. Lewis, A. Knox, D. Stableforth, 2005, The Lancet.

Twice vs three times daily antibiotics in the treatment of pulmonary exacerbations of cystic fibrosis.

A. Knox, A. Smyth, 2011, Journal of Cystic Fibrosis.

Mechanisms involved in desensitization of particulate guanylyl cyclase in human airway smooth muscle: the role of protein kinase C.

A. Knox, A. M. Hamad, 1999, Biochemical and Biophysical Research Communications - BBRC.

Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort

C. Auffray, H. Bisgaard, P. Howarth, 2015, European Respiratory Journal.

Effect of inhaled budesonide on bronchial reactivity to histamine, exercise, and eucapnic dry air hyperventilation in patients with asthma.

A. Tattersfield, A. Knox, A. Wisniewski, 1991, Thorax.

Epigenetic dysregulation of interleukin 8 (CXCL8) hypersecretion in cystic fibrosis airway epithelial cells.

A. Knox, A. Poghosyan, J. Patel, 2016, Biochemical and Biophysical Research Communications - BBRC.

Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease

A. Bittner, M. Polkey, I. Adcock, 2015, The Journal of allergy and clinical immunology.

CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BET

C. Brightling, A. Knox, A. Tatler, 2015, American journal of physiology. Lung cellular and molecular physiology.

A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis

W. Coward, C. Feghali-Bostwick, A. Knox, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial

J. Cockcroft, J. Thornton, T. McKeever, 2015, International journal of chronic obstructive pulmonary disease.

A novel electrospun biphasic scaffold provides optimal three-dimensional topography for in vitro co-culture of airway epithelial and fibroblast cells

A. Ghaemmaghami, A. Knox, F. Rose, 2014, Biofabrication.

Inhibition of polyadenylation reduces inflammatory gene induction.

A. Knox, L. Pang, H. Meijer, 2012, RNA.

A promoter-level mammalian expression atlas

Martin S. Taylor, Jay W. Shin, Thomas J. Ha, 2014, Nature.

Defective Histone Acetylation Is Responsible for the Diminished Expression of Cyclooxygenase 2 in Idiopathic Pulmonary Fibrosis

W. Coward, Keiria Watts, C. Feghali-Bostwick, 2009, Molecular and Cellular Biology.

Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: A longitudinal study; response to comments.

D. Barrett, A. Fogarty, A. Knox, 2017, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

The scientific rationale of combining inhaled glucocorticoids and long acting beta 2 adrenoceptor agonists.

A. Knox, 2002, Current pharmaceutical design.