J. Wharton

J. Gaer, J. Polak, J. Wharton, 1992, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Peptides in the mammalian cardiovascular system

J. Wharton, S. Gulbenkian, 1987, Experientia.

Immunohistochemical and ultrastructural localisation of peptide-containing nerves and myocardial cells in the human atrial appendage

J. Polak, R. Jahn, A. Merighi, 1988, Cell and Tissue Research.

Neural and endocrine peptides in the transplanted heart.

M. Yacoub, J. Polak, J. Wharton, 1990, Seminars in thoracic and cardiovascular surgery.

Enkephalin-, VIP- and substance P-like immunoreactivity in the carotid body

P. Emson, J. Polak, S. Bloom, 1980, Nature.

Vagal origin of substance P-containing nerves in the guinea pig lung

J. Polak, S. Bloom, J. Wharton, 1983, Neuroscience Letters.

Capsaicin induces a depletion of calcitonin gene-related peptide (CGRP)-immunoreactive nerves in the cardiovascular system of the guinea pig and rat.

J. Polak, S. Bloom, J. Wharton, 1986, Journal of the autonomic nervous system.

Ultrastructural evidence for the coexistence of calcitonin gene-related peptide and substance P in secretory vesicles of peripheral nerves in the guinea pig

J. Polak, A. Merighi, J. Wharton, 1986, Journal of neurocytology.

Pulmonary arterial hypertension and the vasoconstrictive factor: is there still a role for vasodilator testing?

J. Wharton, M. Wilkins, J. Gibbs, 2003, European heart journal.

Angiotensin II activates MAPK and stimulates growth of human pulmonary artery smooth muscle via AT1 receptors.

M. Yacoub, J. Polak, N. Morrell, 1999, American journal of physiology. Lung cellular and molecular physiology.

Angiotensin II activates MAPK and stimulates growth of human pulmonary artery smooth muscle via AT 1 receptors

M. Yacoub, J. Polak, N. Morrell, 1999 .

Microvascular substance P binding to normal and inflamed rat and human synovium.

J. Polak, D. A. Walsh, J. Wharton, 1993, The Journal of pharmacology and experimental therapeutics.

Localization of brain and atrial natriuretic peptide in human and porcine heart.

E. Arbustini, J. Polak, P. Needleman, 1992, International journal of cardiology.

Localisation of atrial natriuretic peptide immunoreactivity in the ventricular myocardium and conduction system of the human fetal and adult heart.

A. Khaghani, M. Yacoub, J. Wharton, 1988, British heart journal.

Radioimmunoassay of alpha rat atrial natriuretic peptide

J. Wharton, S. Bloom, N. Christofides, 1986, Neuropeptides.

Neuron-specific enolase as an immunocytochemical marker for the diffuse neuroendocrine system in human fetal lung.

J. Polak, J. Wharton, A. Pearse, 1981, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Differential distribution of angiotensin AT2 receptors in the normal and failing human heart.

R. A. Rutherford, M. Yacoub, J. Catravas, 1998, The Journal of pharmacology and experimental therapeutics.

A study of nerves containing peptides in the pulmonary vasculature of healthy infants and children and of those with pulmonary hypertension.

J. Polak, J. Wharton, S. Haworth, 1989, British heart journal.

Autoradiographic localisation of endothelin binding sites in human and porcine coronary arteries.

J. Polak, S. Bloom, J. Wharton, 1989, European journal of pharmacology.

Species and tissue specificity of vasoactive regulatory peptides.

J. Polak, D. A. Walsh, J. Wharton, 1993, International journal of tissue reactions.

Differences in the distribution and characteristics of tachykinin NK1 binding sites between human and guinea pig lung

J. Polak, D. A. Walsh, J. Wharton, 1994, British journal of pharmacology.

Ventricular and atrial myocytes of newborn rats synthesise and secrete atrial natriuretic peptide in culture: Light-and electron-microscopical localisation and chromatographic examination of stored and secreted molecular forms

J. Polak, A. Merighi, S. Bloom, 2004, Cell and Tissue Research.

Human endocardial innervation and its relationship to the endothelium: an immunohistochemical, histochemical, and quantitative study.

M. Yacoub, J. Polak, J. Wharton, 1994, Cardiovascular research.

Differential distribution of subtypes of specific binding sites of alpha atrial natriuretic peptide in the rat kidney

J. Polak, J. Wharton, R. F. Power, 1988 .

Expression and function of angiotensin converting enzyme, chymase, and angiotensin II in the human radial artery and internal thoracic artery.

M. Amrani, M. Yacoub, J. Wharton, 2000, The Annals of thoracic surgery.

Substance P-like immunoreactive nerves in mammalian lung.

J. Polak, S. Bloom, J. Wharton, 1979, Investigative & cell pathology.

Vasoactive intestinal polypeptide (VIP)-like immunoreactivity in salivary glands.

J. Polak, S. Bloom, J. Wharton, 1979, Life sciences.

Intractable chest pain in cardiomyopathy: treatment by a novel technique of cardiac cryodenervation with quantitative immunohistochemical assessment of success.

W. Mckenna, J. Gaer, J. Polak, 1993, British heart journal.

Differential adrenomedullin release and endothelin receptor expression in distinct subpopulations of human airway smooth-muscle cells.

D. Smith, N. Morrell, J. Wharton, 2001, American journal of respiratory cell and molecular biology.

Circulating Endothelial Progenitor Cells in Patients With Eisenmenger Syndrome and Idiopathic Pulmonary Arterial Hypertension

G. Diller, M. Gatzoulis, J. Wharton, 2008, Circulation.

Iron deficiency in systemic sclerosis patients with and without pulmonary hypertension.

J. Wharton, M. Wilkins, L. Howard, 2014, Rheumatology.

Response to Letter Regarding Article, “Circulating Endothelial Progenitor Cells in Patients With Eisenmenger Syndrome and Idiopathic Pulmonary Arterial Hypertension”

G. Diller, M. Gatzoulis, J. Wharton, 2009 .

The differential distribution of vasoactive intestinal polypeptide in the normal human female genital tract

J. Polak, S. Bloom, J. Wharton, 2004, Histochemistry.

Postnatal development of the innervation and paraganglia in the porcine pulmonary arterial bed

J. Polak, J. Wharton, S. Haworth, 1988, The Journal of pathology.

pulmonary hypertension . children and of those with vasculature of healthy infants and peptides in the pulmonary A study of nerves containing

J. Polak, J. Wharton, S. Haworth, 2022 .

The innervation of guinea pig epicardial coronary veins: immunohistochemistry, ultrastructure and vasomotility.

J. Polak, J. Wharton, L. Edvinsson, 1994, Journal of the autonomic nervous system.

Peptidergic innervation of human epicardial coronary arteries.

J. Polak, J. Wharton, R. Ekman, 1993, Circulation research.

Development of the peptidergic innervation of human heart.

J. Polak, J. Wharton, G. Moscoso, 1993, Journal of anatomy.

Capsaicin induced afferent denervation and receptor-linked responses to CGRP in the rat

J. Polak, J. Wharton, J. McEwan, 1993, Regulatory Peptides.

Comparison of peptidergic mechanisms in different parts of the guinea pig superior mesenteric artery: immunocytochemistry at the light and ultrastructural levels and responses in vitro of large and small arteries.

J. Polak, J. Wharton, L. Edvinsson, 1989, Journal of the autonomic nervous system.

Ultrastructural evidence for the presence of calcitonin gene related peptide and substance P in the same secretory granules in the peripheral nervous system of the guinea pig

J. Polak, A. Merighi, J. Wharton, 1985, Regulatory Peptides.

Localization of endothelinlike immunoreactivity and endothelin binding sites in human colon.

J. Polak, J. Wharton, A. Bishop, 1991, Gastroenterology.

Autoradiographic localization of endothelin-1 binding sites in porcine skin.

J. Polak, J. Wharton, D. Springall, 1991, Journal of Investigative Dermatology.

Expression of neural cell adhesion molecule immunoreactivity in hypertrophic myocardium.

J. Polak, F. Walsh, J. Wharton, 1990, Life Science.

Regional changes in angiotensin II receptor density after experimental myocardial infarction.

R. A. Rutherford, P. Poole‐Wilson, J. Polak, 1996, Journal of molecular and cellular cardiology.

Angiotensin II (AT1) vascular binding sites in human placentae from normal-term, preeclamptic and growth retarded pregnancies.

J. Polak, J. Wharton, M. Sullivan, 1994, The Journal of pharmacology and experimental therapeutics.

Peptidergic innervation of guinea-pig brain vessels: comparison with immunohistochemistry and in vitro pharmacology in rostrally and caudally located arteries.

J. Polak, J. Wharton, L. Edvinsson, 1995, Journal of the Autonomic Nervous System.

Neuropeptide Y modulates the action of vasodilator agents in guinea-pig epicardial coronary arteries

J. Polak, J. Wharton, L. Edvinsson, 1992, Regulatory Peptides.

Neural cell adhesion molecule (N-CAM) expression during cardiac development in the rat

J. Polak, F. Walsh, J. Wharton, 1989, Brain Research.

Expression of functional angiotensin-converting enzyme and AT1 receptors in cultured human cardiac fibroblasts.

M. Yacoub, J. Catravas, J. Polak, 1998, Circulation.

CGRP-immunoreactive nerves in the genitalia of the female rat originate from dorsal root ganglia T11-L3 and L6-S1: A combined immunocytochemical and retrograde tracing study

J. Polak, J. Wharton, H. Su, 1986, Neuroscience Letters.

Endocardial localization and characterization of natriuretic peptide binding sites in human fetal and adult heart.

R. A. Rutherford, M. Yacoub, J. Polak, 1992, European journal of pharmacology.

Atrial amyloid deposits in the failing human heart display both atrial and brain natriuretic peptide‐like immunoreactivity

E. Arbustini, J. Polak, P. Needleman, 1991, The Journal of pathology.

Peptidergic (substance P) nerves in the heart

J. Polak, S. Bloom, J. Wharton, 1980, Regulatory Peptides.

Anatomical Distribution of Vasoactive Intestinal Peptide Binding Sites in Peripheral Tissues Investigated by in Vitro Autoradiography a

J. Polak, S. Bloom, J. Wharton, 1988, Annals of the New York Academy of Sciences.

Endothelin-1 in human skin: immunohistochemical, receptor binding, and functional studies.

C. Bunker, J. Polak, J. Wharton, 1991, Journal of cardiovascular pharmacology.

Localization of endothelin binding sites and endothelin-like immunoreactivity in human fetal heart.

R. A. Rutherford, J. Gaer, J. Polak, 1991, Journal of cardiovascular pharmacology.

Supplementation of iron in pulmonary hypertension: Rationale and design of a phase II clinical trial in idiopathic pulmonary arterial hypertension

P. Robbins, D. Ashby, N. Morrell, 2013, Pulmonary circulation.

Profibrotic Effects of Endothelin-1 via the ETA Receptor in Cultured Human Cardiac Fibroblasts

M. Yacoub, J. Wharton, A. Chester, 2004, Cellular Physiology and Biochemistry.

Metabolomic Insights in Pulmonary Arterial Hypertension

J. Wharton, M. Wilkins, C. Rhodes, 2018, Advances in Pulmonary Hypertension.

Downregulation of natriuretic peptide C-receptor protein in the hypertrophied ventricle of the aortovenocaval fistula rat.

R. A. Rutherford, J. Wharton, M. Wilkins, 1997, Cardiovascular research.

Autoradiographic discrimination of brain and atrial natriuretic peptide-binding sites in the rat kidney.

R. A. Rutherford, J. Polak, P. Needleman, 1991, The Journal of biological chemistry.

S41 Characterisation of mutations in the gene encoding growth and differentiation factor 2 (GDF2) in patients with pulmonary arterial hypertension

M. Haimel, M. Bleda, S. Gräf, 2018, Fundamental mechanisms of pulmonary arterial hypertension.

S40 Phenotypic characterisation of GDF2 mutation carriers in a large cohort of patients with pulmonary arterial hypertension

M. Humbert, W. Seeger, J. Lordan, 2018, Fundamental mechanisms of pulmonary arterial hypertension.

Simvastatin as a treatment for pulmonary hypertension trial.

R. Mohiaddin, P. Nihoyannopoulos, H. Ghofrani, 2010, American journal of respiratory and critical care medicine.

Hypoxia amplifies the proliferative capacity of distal human pulmonary artery smooth-muscle cells.

J. Wharton, K. Banner, E. Growcott, 2005, Chest.

miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia.

Lan Zhao, J. Wharton, M. Wilkins, 2014, The Biochemical journal.

Angiotensin II stimulates proliferation of human pulmonary artery smooth muscle cells via the AT1 receptor.

M. Yacoub, J. Polak, N. Morrell, 1998, Chest.

ET(A) and ET(B) receptors modulate the proliferation of human pulmonary artery smooth muscle cells.

M. Yacoub, J. Polak, N. Morrell, 2002, American journal of respiratory and critical care medicine.

Nitric oxide synthase in human placenta and umbilical cord from normal, intrauterine growth‐retarded and pre‐eclamptic pregnancies

R. A. Rutherford, J. Polak, J. Wharton, 1995, British journal of pharmacology.

Placental nitric oxide synthase visualized by in vitro autoradiography and immunohistochemistry

R. A. Rutherford, J. Polak, J. Wharton, 1993 .

Immunocytochemical application of monoclonal antibodies to rat liver glucocorticoid receptor

C. Bird, J. Wharton, F. Lewis, 1986, The Journal of pathology.

Using the Plasma Proteome for Risk Stratifying Patients with Pulmonary Arterial Hypertension.

M. Humbert, L. Harbaum, J. Lordan, 2022, American journal of respiratory and critical care medicine.

Role of Asymmetric Methylarginine and Connexin 43 in the Regulation of Pulmonary Endothelial Function

J. Wharton, M. Wilkins, B. Wojciak-Stothard, 2013, Pulmonary circulation.

Defective Platelet Lipid Peroxidation in Myeloproliferative Disorders: A Possible Defect of Prostaglandin Synthesis

J. Wharton, A. J. Shepherd, J. Keenan, 1977, British journal of haematology.

Proteomic Analysis of Lung Tissues From Patients With Pulmonary Arterial Hypertension

J. Wharton, M. Wilkins, M. Berryman, 2010, Circulation.

Immunohistochemical demonstration of human cardiac innervation before and after transplantation.

M. Yacoub, J. Polak, J. Wharton, 1990, Circulation research.

Myocardial localization and isoforms of neural cell adhesion molecule (N-CAM) in the developing and transplanted human heart.

M. Yacoub, J. Polak, F. Walsh, 1990, The Journal of clinical investigation.

An organ-on-chip model of pulmonary arterial hypertension identifies a BMPR2-SOX17-prostacyclin signalling axis

J. Edel, A. Fellows, K. Gray, 2022, Communications Biology.

Localization and characterization of neuropeptide Y binding sites in porcine and human colon

J. Polak, D. A. Walsh, J. Wharton, 1993, British journal of pharmacology.

Plasma Metabolomics Implicates Modified Transfer RNAs and Altered Bioenergetics in the Outcomes of Pulmonary Arterial Hypertension

P. Corris, M. Haimel, M. Bleda, 2017, Circulation.

Bombesin-like immunoreactivity in the avian gut and its localisation to a distinct cell type

J. Polak, S. Bloom, J. Wharton, 1979, Histochemistry.

&agr;1-A680T Variant in GUCY1A3 as a Candidate Conferring Protection From Pulmonary Hypertension Among Kyrgyz Highlanders

J. Stasch, T. Aitman, D. Kasperavičiūtė, 2014, Circulation. Cardiovascular genetics.

Peptide-containing nerves in the rat femoral artery and vein. An immunocytochemical and vasomotor study.

J. Polak, J. Wharton, L. Edvinsson, 1989, Blood vessels.

Role of caveolin-1 and cholesterol in transmembrane fatty acid movement.

T. Meshulam, P. Pilch, J. Wharton, 2006, Biochemistry.

Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood

M. Dunning, M. Humbert, P. Corris, 2021, Nature Communications.

Plasma proteome analysis in patients with pulmonary arterial hypertension: an observational cohort study

M. Humbert, H. Ghofrani, R. Schermuly, 2017, The Lancet. Respiratory medicine.

Effects of pregnancy on the extrinsic innervation of the guinea pig uterus. A histochemical, immunohistochemical and ultrastructural study

J. Polak, J. Wharton, P. Alm, 1988, The Histochemical Journal.

Organization of the guinea-pig uterine innervation. Distribution of immunoreactivities for different neuronal markers. Effects of chemical- and pregnancy-induced sympathectomy

J. Polak, J. Wharton, P. Alm, 1988, The Histochemical Journal.

Protein gene product 9.5 (PGP 9.5)

J. Polak, J. Wharton, P. Alm, 1988, Histochemistry.

Therapeutic targets in pulmonary arterial hypertension.

J. Wharton, M. Wilkins, A. Davidson, 2009, Pharmacology & therapeutics.

Why drugs fail in clinical trials in pulmonary arterial hypertension, and strategies to succeed in the future.

J. Wharton, M. Wilkins, C. Rhodes, 2016, Pharmacology & therapeutics.

Differential localization of endothelin ETa and ETB binding sites in human placenta

R. A. Rutherford, J. Polak, J. Wharton, 1993, British journal of pharmacology.

Phosphodiesterase type 5 and high altitude pulmonary hypertension

T. Sooronbaev, N. Morrell, J. Wharton, 2005, Thorax.

Reduced microRNA-150 is associated with poor survival in pulmonary arterial hypertension.

L. Huson, H. Ghofrani, R. Schermuly, 2013, American journal of respiratory and critical care medicine.

Bombesin-like immunoreactivity in the lung

J. Wharton, M. Ghatei, E. Solcia, 1978, Nature.

The application of ‘omics’ to pulmonary arterial hypertension

L. Harbaum, J. Wharton, M. Wilkins, 2020, British journal of pharmacology.

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis

Lisa J. Martin, Keith A. Marsolo, Ferhaan Ahmad, 2018, bioRxiv.

A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach

Dennis Wang, N. Morrell, J. Wharton, 2021, EBioMedicine.

The pathophysiological role of novel pulmonary arterial hypertension gene SOX17

Lan Zhao, J. Wharton, M. Wilkins, 2021, European Respiratory Journal.

Regional distribution and regulation of [125I]calcitonin gene-related peptide binding sites in coronary arteries.

J. Gaer, M. Yacoub, J. Polak, 1992, European journal of pharmacology.

Innervation of human atrioventricular and arterial valves.

M R de Leval, J M Polak, M. Sheppard, 1996, Circulation.

Phosphodiesterase Type 5 as a Target for the Treatment of Hypoxia-Induced Pulmonary Hypertension

Martin R. Wilkins, John Wharton, J. Wharton, 2003, Circulation.

Prolyl-4 Hydroxylase 2 (PHD2) Deficiency in Endothelial Cells and Hematopoietic Cells Induces Obliterative Vascular Remodeling and Severe Pulmonary Arterial Hypertension in Mice and Humans Through Hypoxia-Inducible Factor-2&agr;

J. Wharton, You-yang Zhao, Z. Dai, 2016, Circulation.

Antiproliferative effects of phosphodiesterase type 5 inhibition in human pulmonary artery cells.

J. Wharton, M. Wilkins, S. Phillips, 2005, American journal of respiratory and critical care medicine.

Endothelium-derived microparticles from chronically thromboembolic pulmonary hypertensive patients facilitate endothelial angiogenesis

J. Wharton, B. Wojciak-Stothard, L. Howard, 2016, Journal of Biomedical Science.

Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension.

M. Humbert, L. Harbaum, R. Schermuly, 2022, American journal of respiratory and critical care medicine.

Traffic exposures, air pollution and outcomes in pulmonary arterial hypertension: a UK cohort study analysis

J. Lordan, P. Corris, M. Haimel, 2019, European Respiratory Journal.

Author Correction: Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2

W. Seeger, H. Ghofrani, N. Weissmann, 2021, Communications Biology.

OP-EJEC180212 668..676

D. Rueckert, D. O’Regan, A. Marvao, 2019 .

Heterogeneous binding sites for alpha-atrial natriuretic peptide in human umbilical cord and placenta.

J. Polak, J. Wharton, J. Brown, 1991, The American journal of physiology.

The peptidergic innervation of the human superficial temporal artery: Immunohistochemistry, ultrastructure and vasomotility

J. Wharton, L. Edvinsson, S. Gulbenkian, 1993, Neuropeptides.

Vasoactive Intestinal Peptide Binding Sites in Peripheral Tissues Investigated by in Vitro

J. Wharton, A. Bishop, J. Polak, 2006 .

Calcitonin gene-related peptide immunoreactivity in afferent neurons supplying the urinary tract: Combined retrograde tracing and immunohistochemistry

J. Polak, S. Bloom, J. Wharton, 1986, Neuroscience.

Distribution of vasoactive intestinal polypeptide binding sites in guinea pig genital tissues

J. Polak, S. Bloom, J. Wharton, 1987, Neuroscience Letters.

Phosphodiesterase inhibitors for the treatment of pulmonary hypertension

F. Grimminger, J. Wharton, M. Wilkins, 2008, European Respiratory Journal.

Loss-of-Function ABCC8 Mutations in Pulmonary Arterial Hypertension

W. Chung, Yufeng Shen, F. Dewey, 2018, Circulation. Genomic and precision medicine.

Iron homeostasis and pulmonary hypertension: iron deficiency leads to pulmonary vascular remodeling in the rat.

Lan Zhao, E. Cotroneo, J. Wharton, 2015, Circulation research.

Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension

Fengyuan Hu, Kevin Rue-Albrecht, Patrick Deegan, 2017, Circulation.

Reduced plasma levels of small HDL particles transporting fibrinolytic proteins in pulmonary arterial hypertension

L. Harbaum, J. Nicholson, J. Wharton, 2018, Thorax.

The ADAMTS13–VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension

J. Barberà, M. Simpson, M. Bleda, 2019, European Respiratory Journal.

Phosphodiesterase Inhibitors in the Treatment of Pulmonary Hypertension

Lan Zhao, J. Wharton, M. Wilkins, 2011 .

Identification of renal natriuretic peptide receptor subpopulations by use of the non‐peptide antagonist, HS‐142‐1

R. A. Rutherford, J. Polak, J. Wharton, 1994, British journal of pharmacology.

Emerging therapies for pulmonary arterial hypertension

J. Wharton, M. Wilkins, L. Howard, 2007, Expert opinion on investigational drugs.

Rational : Iron deficiency without anaemia is prevalent in patients with idiopathic pulmonary arterial hypertension and associated with reduced exercise capacity and survival

Lan Zhao, E. Cotroneo, J. Wharton, 2015 .

Integrative Physiology Methods and Results: Rats Were Fed an Iron-deficient Diet (idd, 7 Mg/kg) and Investigated for 4 Weeks. Iron Deficiency Was Evident from Depleted Iron Stores (decreased Liver, Serum Iron, and Ferritin), Reduced Erythropoiesis, and Significantly Decreased Transferrin Saturation

Lan Zhao, E. Cotroneo, J. Wharton, 2022 .

Pulmonary arterial hypertension – progress in understanding the disease and prioritizing strategies for drug development

L. Harbaum, J. Wharton, M. Wilkins, 2017, Journal of internal medicine.

Red cell distribution width outperforms other potential circulating biomarkers in predicting survival in idiopathic pulmonary arterial hypertension

J. Wharton, M. Wilkins, C. Rhodes, 2011, Heart.

S96 Novel biomarkers in idiopathic pulmonary arterial hypertension

J. Wharton, M. Wilkins, C. Rhodes, 2010, Thorax.

Neural cell adhesion molecule is expressed by smooth muscle cells during the development of the rat vascular system

J. Polak, J. Wharton, S. Gulbenkian, 1989, Journal of neurocytology.

Peptide-containing nerve fibres in guinea-pig coronary arteries: immunohistochemistry, ultrastructure and vasomotility.

J. Polak, J. Wharton, L. Edvinsson, 1990, Journal of the autonomic nervous system.

Aberrant Chloride Intracellular Channel 4 Expression Contributes to Endothelial Dysfunction in Pulmonary Arterial Hypertension

D. Irwin, K. Stenmark, S. Yuspa, 2014, Circulation.

A MICROFLUIDIC CHIP FOR PULMONARY ARTERIAL HYPERTENSION

Christopher Rhodes, John Wharton, Luke Howard, 2021 .

Ontogenetic development of the guinea pig uterine innervation

J. Polak, J. Wharton, P. Alm, 2004, Histochemistry.

Expression of the human neuropeptide tyrosine Y 1 receptor ( in situ hybridization / colon / kidney / placenta / cardiovascular system )

J. Polak, J. Wharton, K. Taylor, 2004 .

Simvastatin and sildenafil combine to attenuate pulmonary hypertension

J. Wharton, M. Wilkins, B. Wojciak-Stothard, 2009, European Respiratory Journal.

Endothelium-derived microparticles from chronically thromboembolic pulmonary hypertensive patients facilitate endothelial angiogenesis

J. Wharton, B. Wojciak-Stothard, L. Howard, 2016, Journal of Biomedical Science.

Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cells

J. Wharton, Saliha Afzal, K. Spink, 2006, Respiratory research.

Plasma Metabolomics Implicate Modified Transfer RNAs and Altered Bioenergetics in the Outcome of Pulmonary Arterial Hypertension. 2 Dynamic Risk Stratification of Patient Long-Term Outcome After Pulmonary Endarterectomy: Results From the United Kingdom National Cohort. 2 Initial combination therapy

P. Corris, M. Haimel, M. Bleda, 2016 .

Localisation ofatrial natriuretic peptide immunoreactivity intheventricular myocardiumand conduction systemofthehumanfetal andadultheart

Robert H. Anderson, A. Khaghani, M. Yacoub, 1988 .

Nitric oxide synthase inhumanplacenta andumbilical cordfrom normal, intrauterine growth-retarded andpre-eclamptic pregnancies

J. Wharton, 1995 .

Iron Homeostasis and Pulmonary Hypertension Iron Deficiency Leads to Pulmonary Vascular Remodeling in the Rat

Lan Zhao, E. Cotroneo, J. Wharton, 2015 .

In vitro autoradiographic localisation of regulatory peptide binding sites in guinea-pig uterus

S. Bloom, J. Wharton, J. Polak, 1985, Regulatory Peptides.

Autoradiographic localisation and characterisation of substance P binding sites in rat knees

J. Polak, D. A. Walsh, J. Wharton, 1992, Regulatory Peptides.

Proteomic Analysis of Lung Tissues From Patients With Pulmonary Arterial Hypertension

J. Wharton, M. Wilkins, M. Berryman, 2010, Circulation.

Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells

G. Butrous, J. Wharton, O. Ali, 2011, Respiratory research.

Human PAH is characterized by a pattern of lipid-related insulin resistance.

Y. Shyr, J. Fessel, J. Wharton, 2019, JCI insight.

The application of ‘omics’ to pulmonary arterial hypertension

L. Harbaum, J. Wharton, Pablo Otero-Núñez, 2020, British journal of pharmacology.