P. Mannucci

A. Andriulli, E. Grandone, P. Rebulla, 2016, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Recombinant factor VIIa as haemostatic therapy in advanced liver disease.

M. Franchini, P. Mannucci, 2013, Blood transfusion = Trasfusione del sangue.

New antiplatelet agents in acute coronary syndromes (ACS): an update.

M. Franchini, P. Mannucci, 2010, European journal of internal medicine.

New antiplatelet agents: why they are needed.

M. Franchini, P. Mannucci, 2009, European journal of internal medicine.

Determination of the International Sensitivity Index of a New Near-Patient Testing Device to Monitor Oral Anticoagulant Therapy

P. Mannucci, P. Mannucci, A. Tripodi, 1997, Thrombosis and Haemostasis.

Progression to AIDS among Italian HIV‐seropositive haemophiliacs

P. Mannucci, F. Chiarotti, A. Gringeri, 1991, AIDS.

Activation of the contact system and inflammation after thrombolytic therapy in patients with acute myocardial infarction.

D. Ardissino, P. Mannucci, P. Merlini, 2004, The American journal of cardiology.

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS The Incidence of Venous Thromboembolism in Asymptomatic Carriers of a Deficiency of Antithrombin, Protein C, or Protein S: A Prospective Cohort Study

M. Prins, A. Bura, P. Prandoni, 2016 .

Study Deficiency of Antithrombin, Protein C, or Protein S: A Prospective Cohort The Incidence of Venous Thromboembolism in Asymptomatic Carriers of a

A. Bura, H. Büller, P. Prandoni, 2013 .

The incidence of venous thromboembolism in asymptomatic carriers of a deficiency of antithrombin, protein C, or protein S: a prospective cohort study.

M. Prins, A. Bura, H. Büller, 1999, Blood.

Different risks of thrombosis in four coagulation defects associated with inherited thrombophilia: a study of 150 families.

G. Leone, E. Taioli, V. Rossi, 1998, Blood.

Oral surgery in patients on oral anticoagulant therapy: a randomized comparison of different intensity targets.

P. Mannucci, M. Sacco, R. Sacco, 2007, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

International sensitivity index calibration of the near-patient testing prothrombin time monitor, ProTime.

P. Mannucci, A. Tripodi, V. Chantarangkul, 2003, American journal of clinical pathology.

An ecological alliance against air pollution and cardiovascular disease

P. Mannucci, 2022, Bleeding, Thrombosis, and Vascular Biology.

Predictors of inhibitor eradication by primary immune tolerance induction in severe haemophilia A with high responding inhibitors

M. Margaglione, E. Santagostino, P. Mannucci, 2021, Haemophilia : the official journal of the World Federation of Hemophilia.

Missense or splicing mutation? The case of a fibrinogen Bbeta-chain mutation causing severe hypofibrinogenemia.

P. Mannucci, S. Duga, G. Castaman, 2004, Blood.

Different clinical severity of first episodes and recurrences of thrombotic thrombocytopenic purpura

D. Consonni, P. Mannucci, P. Mannucci, 2010, British journal of haematology.

Phenotype commitment in vascular smooth muscle cells derived from coronary atherosclerotic plaques: differential gene expression of endothelial nitric oxide synthase.

E. Arbustini, E. Bramucci, D. Ardissino, 2009, European journal of histochemistry : EJH.

Thrombogenic potential of human coronary atherosclerotic plaques.

E. Bramucci, D. Ardissino, P. Mannucci, 2001, Blood.

Tissue factor in human coronary atherosclerotic plaques.

E. Bramucci, D. Ardissino, P. Mannucci, 2000, Clinica chimica acta; international journal of clinical chemistry.

Laboratory monitoring of replacement therapy for major surgery in von Willebrand disease

P. Mannucci, M. Franchini, 2017, Haemophilia : the official journal of the World Federation of Hemophilia.

Pregnancy in women with different types of von Willebrand disease.

P. Mannucci, D. Mari, M. Muggiasca, 1986, Obstetrics and gynecology.

Incidence of severe von Willebrand's disease.

P. Mannucci, H. Weiss, A. P. Ball, 1982, The New England journal of medicine.

Patterns of development of tachyphylaxis in patients with haemophilia and von Willebrand disease after repeated doses of desmopressin (DDAVP)

P. Mannucci, M. Cattaneo, Donato Bettega And, 1992, British journal of haematology.

Molecular defects in type 3 von Willebrand disease: updated results from 40 multiethnic patients.

A. Srivastava, P. Mannucci, A. Federici, 2003, Blood cells, molecules & diseases.

Prevention of hemoperitoneum during ovulation by oral contraceptives in women with type III von Willebrand disease and afibrinogenemia. Case reports.

P. Mannucci, D. Mari, E. Bottini, 1991, Haematologica.

Pro-coagulant imbalance in patients with chronic liver disease.

P. Mannucci, A. Tripodi, V. Chantarangkul, 2010, Journal of hepatology.

Introduction. Rare bleeding disorders: general aspects of clinical features, diagnosis, and management.

P. Mannucci, F. Peyvandi, R. Palla, 2009, Seminars in thrombosis and hemostasis.

Antithrombin Milano, Single Amino Acid Substitution at the Reactive Site, Arg393 to Cys

H. Morris, P. Mannucci, M. Panico, 1988, Thrombosis and Haemostasis.

Antithrombin Milano: a new variant with monomeric and dimeric inactive antithrombin III.

P. Mannucci, M. Wolf, D. Meyer, 1985, Blood.

Identification of a new congenital defect of platelet function characterized by severe impairment of platelet responses to adenosine diphosphate.

P. Mannucci, P. Mannucci, M. Cattaneo, 1992, Blood.

Markers of activated coagulation and their usefulness in the clinical laboratory.

P. Mannucci, A. Tripodi, 1996, Clinical chemistry.

Predictive value of fibrinogen in arterial thrombosis

P. Mannucci, D. Mari, 1990 .

A rare inherited coagulation disorder: Combined homozygous factor VII and factor X deficiency

P. Mannucci, F. Peyvandi, I. Garagiola, 2004, American journal of hematology.

Protein C in acute stroke.

P. Mannucci, G. Landi, E. Boccardi, 1988, Stroke.

Cardiovascular health and ambient air pollution: lower is not enough.

P. Mannucci, 2020, European journal of preventive cardiology.

Lack of Correlation Between Activation of Hemostatic Mechanism and Inflammation in Unstable Angina Pectoris

D. Ardissino, A. Pezzano, P. Mannucci, 1998, Journal of Thrombosis and Thrombolysis.

Present and future challanges in the treatment of haemophilia: a clinician's perspective.

M. Franchini, P. Mannucci, 2013, Blood transfusion = Trasfusione del sangue.

Congenital afibrinogenemia: mutations leading to premature termination codons in fibrinogen A alpha-chain gene are not associated with the decay of the mutant mRNAs.

E. Santagostino, P. Mannucci, S. Duga, 2001, Blood.

Appropriateness of prescription of oral anticoagulant therapy in acutely hospitalized older people with atrial fibrillation. Secondary analysis of the SIM‐AF cluster randomized clinical trial

A. Nobili, P. Mannucci, V. Monzani, 2019, British journal of clinical pharmacology.

High Prevalence of Serum Cryoglobulins in Multitransfused Hemophilic Patients With Chronic Hepatitis C

E. Santagostino, P. Mannucci, A. Gringeri, 1998 .

Clinical Manifestations and Management of Inherited Thrombophilia: Retrospective Analysis and Follow-up after Diagnosis of 238 Patients with Congenital Deficiency of Antithrombin III, Protein C, Protein S

T. Barbui, G. Leone, P. Mannucci, 1994, Thrombosis and Haemostasis.

Desmopressin and blood loss after cardiac surgery

P. Mannucci, M. Cattaneo, 1993, The Lancet.

Chapter 60 – Desmopressin (DDAVP)

P. Mannucci, M. Cattaneo, 2013 .

CHAPTER 67 – Desmopressin (DDAVP)

P. Mannucci, M. Cattaneo, 2007 .

Desmopressin in the Treatment of Congenital and Acquired Defects of Platelet Functions

P. Mannucci, M. Cattaneo, 1993 .

Markers of procoagulant imbalance in patients with localized melanomas and autoimmune disorders

R. Scorza, A. Arbini, P. Mannucci, 1993, British journal of haematology.

Inherited thrombophilia: pathogenesis, clinical syndromes, and management.

P. Mannucci, V. De Stefano, P. Mannucci, 1996, Blood.

Formation of methionine sulfoxide by peroxynitrite at position 1606 of von Willebrand factor inhibits its cleavage by ADAMTS-13: A new prothrombotic mechanism in diseases associated with oxidative stress.

S. Rutella, V. De Filippis, P. Mannucci, 2010, Free radical biology & medicine.

αIIbG236E causes Glanzmann thrombasthenia by impairing association with β3

P. Mannucci, P. Mannucci, A. Artoni, 2008, Platelets.

The hemostatic balance revisited through the lessons of mankind evolution

M. Franchini, P. Mannucci, 2008, Internal and Emergency Medicine.

Factor V (Arg506⟶ Gln) Mutation in Young Survivors of Myocardial Infarction

D. Ardissino, P. Mannucci, P. Merlini, 1996, Thrombosis and Haemostasis.

Direct oral anticoagulants and venous thromboembolism

M. Franchini, P. Mannucci, 2016, European Respiratory Review.

Hypercoagulability in acute stroke

A. Morabito, P. Mannucci, G. Landi, 1987, Neurology.

Changes in clinical outcomes for community‐dwelling older people exposed to incident chronic polypharmacy: a comparison between 2001 and 2009

M. Marcucci, A. Nobili, P. Mannucci, 2016, Pharmacoepidemiology and drug safety.

A certification/accreditation model for Haemophilia Centres in Italy.

P. Mannucci, I. Menichini, 2014, Blood transfusion = Trasfusione del sangue.

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

Alberto Piazza, William Matthai, Flora Peyvandi, 2009, Nature Genetics.

Prothrombin Fragment 1+2 and Intensity of Treatment with Oral Anticoagulants

P. Mannucci, A. Tripodi, B. Bottasso, 1991, Thrombosis and Haemostasis.

New anticoagulants for treatment of venous thromboembolism.

M. Franchini, P. Mannucci, 2012, European journal of internal medicine.

Clinical Severity, Age, and Sex Overcome Cardiometabolic Morbidities but Not Stroke as Predictors of Mortality in Elderly Inpatients: Data From the REgistro POliterapie Società Italiana di Medicina Interna Registry

S. Corrao, A. Nobili, F. Perticone, 2016, Journal of the American Geriatrics Society.

The “Diabetes Comorbidome”: A Different Way for Health Professionals to Approach the Comorbidity Burden of Diabetes

S. Corrao, A. Nobili, F. Perticone, 2022, Healthcare.

infections in multitransfused hemophilic patients Serum hepatitis B virus DNA detects cryptic hepatitis B virus

G. Colucci, P. Mannucci, A. Gringeri, 2011 .

The transfusion-associated transmission of parvovirus B19.

P. Mannucci, M. Morfini, P. Mannucci, 1999, Transfusion medicine reviews.

Past, present and future of hemophilia: a narrative review

M. Franchini, P. Mannucci, 2012, Orphanet Journal of Rare Diseases.

Interactions between genotype and phenotype in bleeding and thrombosis

M. Franchini, P. Mannucci, 2008, Haematologica.

Von Willebrand Factor: Another Janus-Faced Hemostasis Protein

M. Franchini, P. Mannucci, Massimo Franchini1, 2008, Seminars in thrombosis and hemostasis.

The management of hemophilia in elderly patients

M. Franchini, P. Mannucci, A. Tagliaferri, 2007, Clinical interventions in aging.

Von Willebrand factor (Vonvendi®): the first recombinant product licensed for the treatment of von Willebrand disease

M. Franchini, P. Mannucci, 2016, Expert review of hematology.

Gastrointestinal angiodysplasia and bleeding in von Willebrand disease

P. Mannucci, M. Franchini, P. Mannucci, 2014, Thrombosis and Haemostasis.

The Use of Plasma‐Derived Concentrates

M. Franchini, P. Mannucci, 2011 .

Thrombotic risk factors: Basic pathophysiology

P. Mannucci, I. Martinelli, P. Bucciarelli, 2010, Critical care medicine.

Risk factors for thrombophilia in extrahepatic portal vein obstruction

P. Mannucci, I. Martinelli, P. Bucciarelli, 2005, Hepatology.

Low Levels of Heparin-releasable Tissue Factor Pathway Inhibitor in Young Patients with Thrombosis

M. Moia, P. Mannucci, R. Ariëns, 1999, Thrombosis and Haemostasis.

Screening for the FV: Q506 Mutation – Evaluation of Thirteen Plasma-based Methods for their Diagnostic Efficacy in Comparison with DNA Analysis

P. Mannucci, R. Bertina, P. Mannucci, 1997, Thrombosis and Haemostasis.

Innovative Pharmacological Therapies for the Hemophilias Not Based on Deficient Factor Replacement

E. Santagostino, M. Franchini, P. Mannucci, 2016, Seminars in Thrombosis & Hemostasis.

Delta infection and liver disease in hemophilic carriers of hepatitis B surface antigen.

D. V. van Thiel, C. Scaroni, P. Mannucci, 1982, The Journal of infectious diseases.

Prophylactic management of patients with von Willebrand disease

M. Franchini, P. Mannucci, Omid Seidizadeh, 2021, Therapeutic advances in hematology.

Alloantibodies in von Willebrand Disease

M. Franchini, P. Mannucci, 2017, Seminars in Thrombosis and Hemostasis.

Activated partial thromboplastin time (APTT). New indications for an old test?

P. Mannucci, A. Tripodi, P. Mannucci, 2006, Journal of thrombosis and haemostasis : JTH.

Post-mortem findings in vaccine-induced thrombotic thrombocytopenia

C. Tripodo, P. Mannucci, F. Sessa, 2021, Haematologica.

Multiple gene interaction and modulation of hemostatic balance

M. Franchini, P. Mannucci, 2009, Clinical chemistry and laboratory medicine.

Management of cerebral and splanchnic vein thrombosis associated with thrombocytopenia in subjects previously vaccinated with Vaxzevria (AstraZeneca): a position statement from the Italian Society for the Study of Haemostasis and Thrombosis (SISET).

G. Tiscia, W. Ageno, P. Mannucci, 2021, Blood transfusion = Trasfusione del sangue.

Primary hyperfibrinolysis: Facts and fancies.

M. Franchini, P. Mannucci, 2018, Thrombosis research.

Adjunct agents for bleeding

M. Franchini, P. Mannucci, 2014, Current opinion in hematology.

Factor V Leiden and G20210A prothrombin mutation and the risk of subclavian vein thrombosis in patients with breast cancer and a central venous catheter.

G. Severi, F. Orsi, A. Goldhirsch, 2004, Annals of oncology : official journal of the European Society for Medical Oncology.

Risk Factors for Deep Venous Thrombosis of the Upper Extremities

E. Taioli, P. Mannucci, I. Martinelli, 1997, Annals of Internal Medicine.

Co‐morbidities and quality of life in elderly persons with haemophilia

M. Franchini, P. Mannucci, 2010, British journal of haematology.

Laboratory Diagnosis of Lupus Anticoagulants for Patients on Oral Anticoagulant Treatment

P. Mannucci, A. Tripodi, V. Chantarangkul, 2002, Thrombosis and Haemostasis.

Factors affecting adherence to guidelines for antithrombotic therapy in elderly patients with atrial ﬁ brillation admitted to internal medicine wards European Journal of Internal Medicine

S. Corrao, M. Marcucci, A. Nobili, 2010 .

The Post-thrombotic Syndrome in Young Women: Retrospective Evaluation of Prognostic Factors

E. Taioli, M. Moia, P. Mannucci, 1998, Thrombosis and Haemostasis.

Multicenter Study of Homocysteine Measurement – Performance Characteristics of Different Methods, Influence of Standards on Interlaboratory Agreement of Results

P. Mannucci, M. Cattaneo, A. Tripodi, 2001, Thrombosis and Haemostasis.

Low Prevalence of Factor V:Q506 in 41 Patients with Isolated Pulmonary Embolism

P. Mannucci, P. Mannucci, I. Martinelli, 1997, Thrombosis and Haemostasis.

Air Pollution, Smoking, and Plasma Homocysteine The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters

L. Hou, A. Baccarelli, A. Zanobetti, 2007 .

Inherited deficiency of antithrombin III in an Italian kindred

P. Mannucci, A. D’Angelo, A. Tripodi, 1980, La Ricerca in clinica e in laboratorio.

Long COVID: A patient perspective

P. Mannucci, P. Marveggio, S. Harari, 2021, European Journal of Internal Medicine.

IgG subclasses as biomarkers for persistence of factor VIII inhibitors in previously untreated patients with severe haemophilia A

F. Rosendaal, P. Mannucci, P. Bucciarelli, 2020, British journal of haematology.

Need for Deprescribing in Hospital Elderly Patients Discharged with a Limited Life Expectancy: The REPOSI Study

A. Nobili, P. Mannucci, L. Cortesi, 2019, Medical Principles and Practice.

Prevalence, characteristics and treatment of chronic pain in elderly patients hospitalized in internal medicine wards.

A. Nobili, P. Mannucci, L. Cortesi, 2018, European journal of internal medicine.

Reply:

G. Barosi, P. Mannucci, P. Bucciarelli, 2007 .

Silica clotting time (SCT) as a screening and confirmatory test for detection of the lupus anticoagulants.

P. Mannucci, A. Arbini, P. Mannucci, 1992, Thrombosis research.

INDOBUFEN VERSUS ASPIRIN PLUS DIPYRIDAMOLE AFTER CORONARY-ARTERY BYPASS-SURGERY

O. Alfieri, M. Lemma, L. Angoli, 1991 .

Mechanisms of Disease The Coagulopathy of Chronic Liver Disease

P. Mannucci, A. Tripodi, 2011 .

Deficiency of (33P)2MeS-ADP Binding Sites on Platelets with Secretion Defect, Normal Granule Stores and Normal Thromboxane A2 Production

P. Mannucci, P. Mannucci, P. Ohlmann, 1997, Thrombosis and Haemostasis.

Ticlopidine Selectively Inhibits Human Platelet Responses to Adenosine Diphosphate

C. Cimminiello, P. Mannucci, P. Mannucci, 1991, Thrombosis and Haemostasis.

Released adenosine diphosphate stabilizes thrombin-induced human platelet aggregates.

P. Mannucci, J. Mustard, R. Kinlough-Rathbone, 1990, Blood.

Molecular genetic analysis of severe coagulation factor XI deficiency in six Italian patients.

E. Santagostino, P. Mannucci, S. Duga, 2004, Haematologica.

Hyperhomocysteinemia as a risk factor for deep-vein thrombosis.

P. Mannucci, I. Martinelli, M. Cattaneo, 1996, The New England journal of medicine.

Autosomal recessive deficiencies of coagulation factors.

P. Mannucci, F. Peyvandi, R. Asselta, 2001, Reviews in clinical and experimental hematology.

Dabigatran versus warfarin in patients with atrial fibrillation.

M. Moia, P. Mannucci, 2009, The New England journal of medicine.

High Prevalence of Hyperhomocysteinemia in Patients with Inflammatory Bowel Disease: a Pathogenic Link with Thromboembolic Complications?

P. Mannucci, I. Martinelli, R. Franchis, 1998, Thrombosis and Haemostasis.

The Coagulopathy of Chronic Liver Disease

P. Mannucci, A. Tripodi, 2012 .

Thrombosis during Pregnancy and Surgery in Patients with Congenital Deficiency of Antithrombin III, Protein C, Protein S

T. Barbui, G. Leone, P. Mannucci, 1994, Thrombosis and Haemostasis.

Long‐term safety and feasibility of arteriovenous fistulae as vascular accesses in children with haemophilia: a prospective study

P. Mannucci, E. Santagostino, P. Mannucci, 2003, British journal of haematology.

Inflammatory bowel disease are not associated with the major hereditary conditions predisposing to thrombosis

E. Sacchi, P. Mannucci, R. Franchis, 1998 .

Homeopathy provided by a national health service: Only in Italy?

S. Garattini, P. Mannucci, 2017, European journal of internal medicine.

How to evaluate the influence of blood collection systems on the international sensitivity index. Protocol applied to two new evacuated tubes and eight coagulometer/thromboplastin combinations.

P. Mannucci, A. Tripodi, V. Chantarangkul, 2002, Thrombosis research.

Assessment of the influence of citrate concentration on the International Normalized Ratio (INR) determined with twelve reagent-instrument combinations.

P. Mannucci, A. Tripodi, V. Chantarangkul, 1998, Thrombosis and haemostasis.

Risk of Pregnancy-related Venous Thrombosis in Carriers of Severe Inherited Thrombophilia

E. Grandone, P. Mannucci, I. Martinelli, 2001, Thrombosis and Haemostasis.

Simulation-based education for physicians to increase oral anticoagulants in hospitalized elderly patients with atrial fibrillation.

M. Marcucci, P. Santalucia, A. Nobili, 2019, The American journal of medicine.

Direct oral anticoagulants and cirrhosis: More evidence still needed for efficacy and safety in portal vein thrombosis.

P. Mannucci, A. Tripodi, 2019, Vascular pharmacology.

Arg2074Cys missense mutation in the C2 domain of factor V causing moderately severe factor V deficiency: molecular characterization by expression of the recombinant protein.

E. Santagostino, P. Mannucci, S. Duga, 2003, Blood.

Increased Thrombin Generation in Inflammatory Bowel Diseases

P. Mannucci, S. Bruno, R. Franchis, 2008 .

Decrease and rapid recovery of protein C after plasma exchange

P. Walsh, P. Mannucci, J. Lewis, 1986, Transfusion.

Homozygous protein C deficiency with moderately severe clinical symptoms.

P. Mannucci, A. Tripodi, M. Tirindelli, 1986, Thrombosis research.

Treatment with stanazolol of type I protein C deficiency in an Italian family

P. Mannucci, P. Mannucci, A. Tripodi, 1984, La Ricerca in Clinica e in Laboratorio.

FREQUENCY OF FACTOR V LEIDEN AND PROTHROMBIN POLYMORPHISM IN SOUTH OF IRAN

P. Mannucci, M. Bordbar, J. Dehbozorgian, 2009 .

Activated partial thromboplastin time: results of a case–control study evaluating six commercial reagents in assessing the risk of venous thromboembolism

P. Mannucci, I. Martinelli, A. Tripodi, 2006, Journal of thrombosis and haemostasis : JTH.

Anti-COVID-19 vaccines and rare cases of cerebral venous sinus thrombosis with thrombocytopenia: what about the pragmatic benefit/risk evaluation for still unvaccinated young women

F. Lapi, P. Mannucci, E. Marconi, 2022, Expert review of vaccines.

New anticoagulants in internal medicine: an update.

M. Franchini, P. Mannucci, 2010, European journal of internal medicine.

Failure of recombinant activated factor VII during surgery in a hemophiliac with high-titer factor VIII antibody.

E. Santagostino, P. Mannucci, A. Gringeri, 1991, Haemostasis.

Interference of factor V Leiden on protein S activity: evaluation of a new prothrombin time-based assay

P. Mannucci, A. Tripodi, V. Chantarangkul, 2007, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Is haemophilia B less severe than haemophilia A?

P. Mannucci, M. Franchini, P. Mannucci, 2013, Haemophilia : the official journal of the World Federation of Hemophilia.

Vagaries of genetic association studies in myocardial infarction.

D. Ardissino, P. Mannucci, P. Merlini, 2003, Blood.

A novel two base pair deletion in the factor V gene associated with severe factor V deficiency.

E. Santagostino, P. Mannucci, S. Duga, 2000 .

A novel two base pair deletion in the factor V gene associated with severe factor V deficiency

P. Mannucci, E. Santagostino, P. Mannucci, 2000, British journal of haematology.

Treatment of haemophilia: building on strength in the third millennium

P. Mannucci, 2011, Haemophilia : the official journal of the World Federation of Hemophilia.

What changed in the Italian internal medicine and geriatric wards during the lockdown

B. D'avanzo, A. Nobili, P. Mannucci, 2020, European Journal of Internal Medicine.

ANTIBODIES TO TISSUE-TYPE PLASMINOGEN ACTIVATOR (tPA) IN PATIENTS WITH ANTIPHOSPHOLIPID SYNDROME. EVIDENCE OF INTERACTION BETWEEN THE ANTIBODIES AND THE CATALYTIC DOMAIN OF tPA IN TWO PATIENTS Anti-tPA antibodies in antiphospholipid syndrome

R. Russo, P. Mannucci, P. Meroni, 2003 .

Warfarin and acenocoumarol dose requirements according to CYP2C9 genotyping in North‐Italian patients

M. Moia, P. Mannucci, F. Peyvandi, 2003, Journal of thrombosis and haemostasis : JTH.

Accelerated schedule of hepatitis B vaccination in patients with hemophilia

E. Santagostino, P. Mannucci, A. Rocino, 1993, Journal of medical virology.

Exercise training in mild hypertension: effects on blood pressure, left ventricular mass and coagulation factor VII and fibrinogen.

P. Mannucci, O. Agostoni, D. Bettega, 1997, The Cardiology.

Inherited factors in thrombosis.

P. Mannucci, A. Tripodi, 1988, Blood reviews.

Comparison of a functional assay for protein C with two immunoassays.

P. Mannucci, A. Tripodi, B. Bottasso, 1985, Thrombosis research.

Fibrinolytic shut‐down after surgery: impairment of the balance between tissue‐type plasminogen activator and its specific inhibitor

P. Mannucci, J. Verheijen, C. Kluft, 1985, European journal of clinical investigation.

The complex differential diagnosis between thrombotic thrombocytopenic purpura and the atypical hemolytic uremic syndrome: Laboratory weapons and their impact on treatment choice and monitoring.

P. Mannucci, M. Cugno, 2015, Thrombosis research.

Advantages and limits of ADAMTS13 testing in thrombotic thrombocytopenic purpura.

M. Franchini, P. Mannucci, 2008, Blood transfusion = Trasfusione del sangue.

Clinical and laboratory patterns of the haemolytic uraemic syndrome and thrombotic thrombocytopenic purpura in southern Iran

P. Mannucci, F. Peyvandi, M. Karimi, 2006, Internal and emergency medicine.

Purinoceptors on blood platelets: further pharmacological and clinical evidence to suggest the presence of two ADP receptors

P. Mannucci, P. Mannucci, J. Cazenave, 1995, British journal of haematology.

ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission

F. Fabris, P. Mannucci, T. Battaglioli, 2008, Haematologica.

TTP and ADAMTS 13 : When Is Testing Appropriate ?

P. Mannucci, F. Peyvandi, 2007 .

TTP and ADAMTS13: When Is Testing Appropriate?

P. Mannucci, F. Peyvandi, 2007, Hematology. American Society of Hematology. Education Program.

Inhibitor eradication with rituximab in haemophilia: where do we stand?

M. Franchini, P. Mannucci, 2014, British journal of haematology.

DDAVP enhances platelet adherence and platelet aggregate growth on human artery subendothelium.

J. Sixma, P. Mannucci, K. Sakariassen, 1984, Blood.

Impact of Dietary Fats on Cardiovascular Disease with a Specific Focus on Omega-3 Fatty Acids

A. Maggioni, P. Mannucci, G. Poli, 2022, Journal of clinical medicine.

Desmopressin: a nontransfusional treatment of hemophilia and von Willebrand disease.

P. Mannucci, M. Cattaneo, 1992, Haemostasis.

Congenital plasminogen deficiency associated with venous thromboembolism: therapeutic trial with stanozolol

P. Mannucci, C. Kluft, A. D’Angelo, 1986, British journal of haematology.

Thrombotic microangiopathies: the past as prologue.

P. Mannucci, 2013, European journal of internal medicine.

PLASMA LEVELS OF THE VON WILLEBRAND FACTOR-CLEAVING PROTEASE IN PHYSIOLOGICAL AND PATHOLOGICAL CONDITIONS IN CHILDREN

P. Mannucci, K. Kavaklı, M. Canciani, 2002, Pediatric hematology and oncology.

Coagulation and platelet activation after retinal vein occlusions.

P. Mannucci, D. Mari, G. Bertoni, 1982, Haemostasis.

Safety and immunogenicity of HIV-1 Tat toxoid in immunocompromised HIV-1-infected patients.

W. Blattner, A. Burny, E. Santagostino, 1998, Journal of human virology.

Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease

Simon C. Potter, Thomas W. Mühleisen, Benjamin J. Wright, 2011, PLoS genetics.

Platelets and the vessel wall: how much aspirin?

P. Mannucci, A. D’Angelo, J. Smith, 1980, Lancet.

High prevalence of antibody to hepatitis C virus in multitransfused hemophiliacs with normal transaminase levels.

P. Mannucci, A. Gringeri, M. Colombo, 1990, Annals of internal medicine.

Rotational thromboelastography for monitoring of fibrinogen concentrate therapy in fibrinogen deficiency

P. Mannucci, F. Peyvandi, S. Knaub, 2008, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Characterization of fibrinogen Milano I: amino acid exchange gamma 330 Asp----Val impairs fibrin polymerization.

P. Mannucci, A. Henschen, M. Furlan, 1986, Blood.

Factor VIII activity as measured by an amidolytic assay compared with a one-stage clotting assay.

P. Mannucci, A. Tripodi, 1986, American journal of clinical pathology.

Sustainable and personalized nutrition: From earth health to public health.

A. Astrup, S. Boccia, P. Mannucci, 2021, European journal of internal medicine.

Evaluation of the Abnormal Platelet Function in von Willebrand Disease by the Blood Filtration Test

P. Mannucci, Z. Ruggeri, M. Cattaneo, 1996, Thrombosis and Haemostasis.

Factor VIII clotting activity

P. Mannucci, A. Tripodi, 1999 .

Perspective - The case for zero bleeds and drug bioequivalence in the treatment of congenital hemophilia A in 2021.

A. Di Minno, P. Mannucci, G. Di Minno, 2021, Blood reviews.

Effects of Oral Contraceptives and Obesity on Protein C Antigen

P. Mannucci, T. Meade, Y. Stirling, 1985, Thrombosis and Haemostasis.

Serum hepatitis B virus DNA detects cryptic hepatitis B virus infections in multitransfused hemophilic patients.

G. Colucci, P. Mannucci, A. Gringeri, 1990, Blood.

Liver dysfunction rather than intravascular coagulation as the main cause of low protein C and antithrombin III in acute leukemia

T. Barbui, P. Mannucci, F. Rodeghiero, 1984 .

Hypercoagulability in congenital haemolytic anaemias.

M. Franchini, P. Mannucci, 2012, Blood transfusion = Trasfusione del sangue.

Hemolytic uremic syndrome in adults.

C. Ponticelli, P. Mannucci, E. Imbasciati, 1980, Archives of internal medicine.

Coinheritance of the HR 2 Haplotype in the Factor V Gene Confers an Increased Risk of Venous Thromboembolism to Carriers of Factor V R 506 Q ( Factor V Leiden )

M. Margaglione, P. Mannucci, P. Bucciarelli, 1999 .

State of Care for Hemophilia in Pediatric Patients

E. Santagostino, P. Mannucci, A. Gringeri, 2002, Paediatric drugs.

Effect of prothrombin 19911 A>G polymorphism on the risk of cerebral sinus‐venous thrombosis

P. Mannucci, A. Tosetto, I. Martinelli, 2010, European journal of neurology.

Collaborative Study for the Calibration of a Proposed Reference Preparation for Thromboplastin , Human Recombinant , Plain On behalf of the Subcommittee on Control of Anticoagulation

P. Mannucci, A. Tripodi, V. Chantarangkul, 2017 .

Letter: Enhanced factor VIII activity in von Willebrand's disease.

P. Mannucci, Z. Ruggeri, F. Pareti, 1974, The New England journal of medicine.

The Role of Thrombophilia in Splanchnic Vein Thrombosis

P. Mannucci, M. Primignani, Pier Mannucci2, 2008, Seminars in liver disease.

Hyperhomocysteinemia in cerebral vein thrombosis.

P. Mannucci, I. Martinelli, T. Battaglioli, 2003, Blood.

Report of the Working Party on Acquired Inhibitors of Coagulation: Studies of the “Lupus” Anticoagulant

P. Mannucci, P. Mannucci, C. Rizza, 1983, Thrombosis and Haemostasis.

Progressive decrease of the healthcare impact of the post‐COVID condition after the first disease wave in Lombardy, Italy

B. D'avanzo, G. Remuzzi, S. Harari, 2022, Journal of internal medicine.

Correction of the bleeding time in treated patients with severe von willebrand disease is not solely dependent on the normal multimeric structure of plasma von willebrand factor

P. Mannucci, P. Rebulla, M. Moia, 1987, American journal of hematology.

Blood lead levels following consumption of game meat in Italy

D. Consonni, S. Fustinoni, P. Mannucci, 2017, Environmental research.

A multicenter controlled, randomized, open trial of interferon alpha2b treatment of anti-human immunodeficiency virus-negative hemophilic patients with chronic hepatitis C. Hepatitis Study Group of the Association of Italian Hemophilia Centers.

P. Pontisso, M. Morfini, E. Santagostino, 1997, Blood.

of action independent of released von Willebrand factor Willebrand disease treated with cryoprecipitate. Evidence for a mechanism DDAVP shortens the prolonged bleeding times of patients with severe von

M. Moia, P. Mannucci, M. Cattaneo, 2011 .

DDAVP shortens the prolonged bleeding times of patients with severe von Willebrand disease treated with cryoprecipitate. Evidence for a mechanism of action independent of released von Willebrand factor

M. Moia, P. Mannucci, M. Cattaneo, 1989 .

M. Moia, P. Mannucci, M. Cattaneo, 1989, Blood.

Randomized controlled trial of desmopressin plus terlipressin vs. terlipressin alone for the treatment of acute variceal hemorrhage in cirrhotic patients: a multicenter, double-blind study. New Italian Endoscopic Club.

P. Mannucci, P. Arcidiacono, R. de Franchis, 1993, Hepatology.

In vitro effects of picotamide on human platelet aggregation, the release reaction and thromboxane B2 production.

P. Mannucci, M. Cattaneo, A. Lecchi, 1991, Thrombosis research.

Genetic characterization of patients with Bernard-Soulier syndrome and their relatives from Southern Iran

P. Mannucci, F. Peyvandi, M. Karimi, 2007, Platelets.

Getting rid of refractory hemophilia.

P. Mannucci, 2012, Blood.

Telemedicine and telerehabilitation: current and forthcoming applications in haemophilia.

P. Mannucci, E. Boccalandro, Giuseppe Dallari, 2019, Blood transfusion = Trasfusione del sangue.

Risk of venous thromboembolism after air travel: interaction with thrombophilia and oral contraceptives.

E. Taioli, P. Mannucci, I. Martinelli, 2003, Archives of Internal Medicine.

Desmopressin in Bleeding Disorders

P. Mannucci, M. Cattaneo, G. Mariani, 1993, NATO ASI Series.

Factor VII Clotting Assay: Influence of Different Thromboplastins and Factor VII-Deficient Plasmas

P. Mannucci, G. Mariani, P. Mannucci, 1991, Thrombosis and Haemostasis.

Prophylaxis for adults with haemophilia: towards a personalised approach?

M. Franchini, P. Mannucci, 2012, Blood transfusion = Trasfusione del sangue.

Tailoring care to haemophilia patients' needs: which specialty and when?

V. Jiménez‐Yuste, G. Benson, R. Ljung, 2015, Blood transfusion = Trasfusione del sangue.

the COCIS Study Group Cost of care and quality of life in hemophilia complicated by inhibitors

L. Mantovani, P. Mannucci, L. Scalone, 2013 .

by inhibitors: the COCIS Study Group Cost of care and quality of life for patients with hemophilia complicated

L. Mantovani, P. Mannucci, L. Scalone, 2013 .

Quality of life is associated to the orthopaedic status in haemophilic patients with inhibitors

L. Mantovani, P. Mannucci, L. Scalone, 2006, Haemophilia : the official journal of the World Federation of Hemophilia.

Cost of care and quality of life for patients with hemophilia complicated by inhibitors: the COCIS Study Group.

L. Mantovani, P. Mannucci, L. Scalone, 2003, Blood.

The Thrombogram in Rare Inherited Coagulation Disorders: Its Relation to Clinical Bleeding

Flora Peyvandi, H. Hemker, R. al Dieri, 2002, Thrombosis and Haemostasis.

Inherited risk factors for venous thromboembolism

P. Mannucci, I. Martinelli, V. Stefano, 2014, Nature Reviews Cardiology.

Kreuth IV: European consensus proposals for treatment of haemophilia with coagulation factor concentrates

P. Giangrande, P. Mannucci, W. Schramm, 2017, Haemophilia : the official journal of the World Federation of Hemophilia.

Kreuth III: European consensus proposals for treatment of haemophilia with coagulation factor concentrates

P. Mannucci, P. Giangrande, P. Mannucci, 2014, Haemophilia : the official journal of the World Federation of Hemophilia.

Haemophilia B is clinically less severe than haemophilia A: further evidence.

M. Franchini, P. Mannucci, 2018, Blood transfusion = Trasfusione del sangue.

Modifiers of clinical phenotype in severe congenital hemophilia.

M. Franchini, P. Mannucci, 2017, Thrombosis research.

Involvement of the IgE‐basophil system and mild complement activation in haemophilia B with anti‐factor IX neutralizing antibodies and anaphylaxis

E. Santagostino, P. Mannucci, M. Mancuso, 2017, Haemophilia : the official journal of the World Federation of Hemophilia.

Consumption of clotting factors in severe haemophilia patients undergoing prophylaxis and on‐demand treatment in Italy

P. Mannucci, F. Abbonizio, A. Giampaolo, 2011, Transfusion medicine.

Kreuth V initiative: European consensus proposals for treatment of hemophilia using standard products, extended half-life coagulation factor concentrates and non-replacement therapies

K. Buchheit, U. Mansmann, P. Mannucci, 2020, Haematologica.

Management of Hemophilia in Older Patients

M. Franchini, P. Mannucci, 2017, Drugs & Aging.

Polypharmacy in older adults with severe haemophilia

A. Nobili, E. Santagostino, P. Mannucci, 2018, Haemophilia : the official journal of the World Federation of Hemophilia.

Models for institutional and professional accreditation of haemophilia centres in Italy

M. Morfini, E. Santagostino, P. Mannucci, 2013, Haemophilia : the official journal of the World Federation of Hemophilia.

Biological Responses to Repeated Doses of Desmopressin (DDAVP) in Patients with Hemophilia and Von Wille Brand’s Disease

P. Mannucci, M. Cattaneo, D. Bettega, 1993 .

Use of desmopressin in the treatment of hemophilia A: towards a golden jubilee

P. Mannucci, 2018, Haematologica.

Missense mutations in the human beta fibrinogen gene cause congenital afibrinogenemia by impairing fibrinogen secretion.

P. Mannucci, E. Santagostino, P. Mannucci, 2000, Blood.

Reply to: The importance and challenge of pediatric trials of hemophilia drugs

F. Rosendaal, P. Mannucci, F. Peyvandi, 2014, Nature Network Boston.

Intracranial haemorrhage in the Italian population of haemophilia patients with and without inhibitors

A. Iorio, P. Mannucci, G. Castaman, 2012, Haemophilia : the official journal of the World Federation of Hemophilia.

Management of orthopaedic surgery in rare bleeding disorders

P. Mannucci, F. Peyvandi, G. Pasta, 2014, Haemophilia : the official journal of the World Federation of Hemophilia.

High efficacy of combined therapy with pegylated interferon plus ribavirin in patients with hemophilia and chronic hepatitis C.

E. Santagostino, P. Mannucci, A. Coppola, 2006, Haematologica.

Managing prostatic illness in persons with haemophilia

P. Mannucci, M. Makris, 2022, Haemophilia.

Laboratory Screening of Inherited Thrombotic Syndromes

P. Mannucci, P. Mannucci, A. Tripodi, 1987, Thrombosis and Haemostasis.

What is the importance of the 'small pool concept' in the preparation of fraciton I and cryoprecipitates for the prevention of post-transfusion hepatitis?

K. R. Woods, J. Mercer, A. Zuckerman, 1980, Vox sanguinis.

Transmission of hepatitis G virus in patients with angioedema treated with steam‐heated plasma concentrates of C1 inhibitor

P. Mannucci, M. Cicardi, E. Silini, 1998, Transfusion.

Reduction in transmission of hepatitis C after the introduction of a heat‐treatment step in the production of C1‐inhibitor concentrate

P. Mannucci, M. Cicardi, A. Agostoni, 1995, Transfusion.

Platelet aggregation at high shear is impaired in patients with congenital defects of platelet secretion and is corrected by DDAVP: correlation with the bleeding time.

P. Mannucci, M. Cattaneo, A. Lecchi, 1995, The Journal of laboratory and clinical medicine.

Abnormalities of hemostasis and bleeding in chronic liver disease: the paradigm is challenged

P. Mannucci, A. Tripodi, M. Primignani, 2010, Internal and emergency medicine.

The European Haemophilia Network (EUHANET).

T. Lambert, P. Mannucci, M. Makris, 2014, Blood transfusion = Trasfusione del sangue.

The increased demand for plasma-derived factor VIII in Italy.

P. Mannucci, G. Calizzani, R. Arcieri, 2017, Blood transfusion = Trasfusione del sangue.

The demand for factor VIII and for factor IX and the toll fractionation product surplus management.

M. Franchini, P. Mannucci, S. Vaglio, 2013, Blood transfusion = Trasfusione del sangue.

The European standards of Haemophilia Centres.

P. Giangrande, P. Mannucci, M. Makris, 2014, Blood transfusion = Trasfusione del sangue.

Ageing successfully with haemophilia: A multidisciplinary programme

E. Santagostino, P. Mannucci, S. Riva, 2018, Haemophilia : the official journal of the World Federation of Hemophilia.

Timing and severity of inhibitor development in recombinant versus plasma‐derived factor VIII concentrates: a SIPPET analysis

F. Rosendaal, P. Mannucci, F. Peyvandi, 2018, Journal of thrombosis and haemostasis : JTH.

Half-life extension technologies for haemostatic agents.

P. Mannucci, 2014, Thrombosis and haemostasis.

Erratum: The hemophilias - From royal genes to gene therapy (New England Journal of Medicine (June 7, 2001) 344 (1773-9))

Edward G. D. Tuddenham, P. Mannucci, E. Tuddenham, 2001 .

Von Willebrand disease combined with coagulation defects in Iran.

P. Mannucci, F. Peyvandi, M. Ahmadinejad, 2021, Blood transfusion = Trasfusione del sangue.

The Italian AICE-Genetics hemophilia A database: results and correlation with clinical phenotype

M. Margaglione, E. Grandone, F. Torricelli, 2008, Haematologica.

Prediction of factor VIII inhibitor development in the SIPPET cohort by mutational analysis and factor VIII antigen measurement

F. Rosendaal, P. Mannucci, F. Peyvandi, 2018, Journal of thrombosis and haemostasis : JTH.

Italian Registry of Haemophilia and Allied Disorders. Objectives, methodology and data analysis

M Morfini, P M Mannucci, A. Iorio, 2008, Haemophilia : the official journal of the World Federation of Hemophilia.

The More Recent History of Hemophilia Treatment.

M. Franchini, P. Mannucci, 2022, Seminars in thrombosis and hemostasis.

Factor VIII Deficiency or Hemophilia A: Clinical Bleeding and Management

M. Franchini, P. Mannucci, 2014 .

Transmission of parvovirus B19 by coagulation factor concentrates exposed to 100°C heat after lyophilization

M. Morfini, E. Santagostino, P. Mannucci, 1997 .

Incidence of low‐titre factor VIII inhibitors in patients with haemophilia A: meta‐analysis of observational studies

P. Mannucci, P. Mannucci, A. Messori, 2017, Haemophilia : the official journal of the World Federation of Hemophilia.

POST-TRANSFUSION HEPATITIS AFTER PROTHROMBIN COMPLEX CONCENTRATES

P. Mannucci, 1979, The Lancet.

Glanzmann thrombasthenia and Bernard-Soulier syndrome in south Iran.

P. Mannucci, P. Mannucci, F. Peyvandi, 2005, Clinical and laboratory haematology.

Intelligent game engines for home exercises (exergames) in boys with haemophilia

P. Mannucci, E. Boccalandro, Valentina Begnozzi, 2020, Haemophilia : the official journal of the World Federation of Hemophilia.

Genetic risk stratification to reduce inhibitor development in the early treatment of hemophilia A: a SIPPET analysis.

F. Rosendaal, P. Mannucci, F. Peyvandi, 2017, Blood.

Transmission of parvovirus B19 by coagulation factor concentrates exposed to 100 degrees C heat after lyophilization.

M. Morfini, E. Santagostino, P. Mannucci, 1997, Transfusion.

Treatment of Hemophilia - More Amazing Progress.

P. Mannucci, 2020, The New England journal of medicine.

Lupus anticoagulants and their relationship with the inhibitors against coagulation factor VIII: considerations on the differentiation between the 2 circulating anticoagulants.

E. Santagostino, P. Mannucci, P. Meroni, 2005, Clinical chemistry.

Nonneutralizing antibodies against factor VIII and risk of inhibitor development in severe hemophilia A.

F. Rosendaal, P. Mannucci, F. Peyvandi, 2017, Blood.

Comparative analysis of the pivotal studies of extended half‐life recombinant FVIII products for treatment of haemophilia A

P. Cortesi, L. Mantovani, P. Mannucci, 2021, Haemophilia : the official journal of the World Federation of Hemophilia.

Acquired haemophilia A: A 2013 update

Massimo Franchini, M. Franchini, P. Mannucci, 2013, Thrombosis and Haemostasis.

Porcine recombinant factor VIII: an additional weapon to handle anti-factor VIII antibodies.

M. Franchini, P. Mannucci, 2017, Blood transfusion = Trasfusione del sangue.

PROTEIN C CONCENTRATES FOR THERAPEUTIC USE

P. Mannucci, S. Viganò, S. Viganó, 1983, The Lancet.

Risk of thromboembolic complications in patients with inflammatory bowel disease

P. Mannucci, R. Franchis, M. Vecchi, 1992 .

Miracle of haemophilia drugs: Personal views about a few main players

P. Mannucci, 2018, Haemophilia : the official journal of the World Federation of Hemophilia.

Von Willebrand disease‐associated angiodysplasia: a few answers, still many questions

M. Franchini, P. Mannucci, 2013, British journal of haematology.

Are all licensed haemostatic agents for haemophilia therapy accessible to patients?

P. Mannucci, W. Schramm, K. Kavaklı, 2022, Haemophilia : the official journal of the World Federation of Hemophilia.

Multimorbidity and polypharmacy in the elderly: lessons from REPOSI

A. Nobili, P. Mannucci, R. Investigators, 2014, Internal and Emergency Medicine.

Rate and appropriateness of polypharmacy in older patients with hemophilia compared with age‐matched controls

A. Iorio, A. Nobili, E. Santagostino, 2018, Haemophilia : the official journal of the World Federation of Hemophilia.

Virology of the Hepatitis A Epidemic in Italy

S. Emerson, R. Purcell, P. Mannucci, 1994, Vox sanguinis.

Clinical manifestations in 28 Italian and Iranian patients with severe factor VII deficiency

P. Mannucci, P. Mannucci, F. Peyvandi, 1997, Haemophilia : the official journal of the World Federation of Hemophilia.

Pharmacokinetics and safety of a novel recombinant human von Willebrand factor manufactured with a plasma-free method: a prospective clinical trial.

C. Kempton, P. Mannucci, E. Romond, 2013, Blood.

Reduced FVIII recovery associated with anti-FVIII PEG antibodies after BNT162b2 SARS-CoV-2 vaccination

A. Ciavarella, P. Mannucci, F. Peyvandi, 2022, Blood Advances.

Novel investigations on the protective role of the FVIII/VWF complex in inhibitor development

P. Mannucci, P. Mannucci, R. Klamroth, 2014, Haemophilia : the official journal of the World Federation of Hemophilia.

Changes of Prothrombin Fragment 1+2 (F 1+2) as a Function of Increasing Intensity of Oral Anticoagulation

P. Mannucci, B. Cesana, M. Cattaneo, 1998, Thrombosis and Haemostasis.

Von Willebrand disease type 2N: An update

P. Mannucci, F. Peyvandi, Omid Seidizadeh, 2021, Journal of thrombosis and haemostasis : JTH.

High-titre inhibitors in previously untreated patients with severe haemophilia A receiving recombinant or plasma-derived factor VIII: a budget-impact analysis.

F. Rosendaal, P. Mannucci, A. Messori, 2018, Blood transfusion = Trasfusione del sangue.

Recommendations for factor VIII product source to treat patients with haemophilia A.

P. Mannucci, G. Calizzani, R. Arcieri, 2017, Blood transfusion = Trasfusione del sangue.

Choices of factor VIII products in previously untreated patients with haemophilia A: A global survey

F. Rosendaal, A. Nobili, P. Mannucci, 2018, Haemophilia : the official journal of the World Federation of Hemophilia.

Acquired von Willebrand syndrome: focused for hematologists

M. Franchini, P. Mannucci, 2020, Haematologica.

Haemophilia Centre Certification Systems: optional or optimal choice for healthcare systems?

D. Taruscio, P. Mannucci, M. Makris, 2014, Blood transfusion = Trasfusione del sangue.

Plasma-derived medicinal products: demand and clinical use.

P. Mannucci, G. Grazzini, F. Oleari, 2013, Blood transfusion = Trasfusione del sangue.

High rates of hepatitis G virus infection in multitransfused patients with hemophilia.

A. Zanella, P. Mannucci, D. Prati, 1997, Blood.

Genotypes of European and Iranian patients with type 3 von Willebrand disease enrolled in 3WINTERS-IPS.

P. Mannucci, A. Tosetto, J. Goudemand, 2021, Blood advances.

Characterization of Partial Gene Deletions in Type III von Willebrand Disease with Alloantibody Inhibitors

P. Mannucci, D. Mancuso, J. Evan Sadler, 1994, Thrombosis and Haemostasis.

Analysis of Iranian patients allowed the identification of the first truncating mutation in the fibrinogen Bbeta-chain gene causing afibrinogenemia.

P. Mannucci, S. Duga, F. Peyvandi, 2002, Haematologica.

Pediatric requirements in Europe stymie help for hemophilia

F. Rosendaal, P. Mannucci, F. Peyvandi, 2014, Nature Medicine.

Viral Safety of Factor VIII Concentrates

P. Mannucci, P. Foster, 1994 .

Recombinant porcine factor VIII: a new instalment of a long story

P. Mannucci, P. Mannucci, 2015, Haemophilia : the official journal of the World Federation of Hemophilia.

Sustained suppression of hepatitis C virus by interferon and ribavirin in hemophilic patients not responding to interferon monotherapy.

E. Santagostino, P. Mannucci, M. Colombo, 2002, Blood.

Comorbidities in persons with haemophilia aged 60 years or more compared with age‐matched people from the general population

A. Iorio, E. Santagostino, P. Mannucci, 2018, Haemophilia : the official journal of the World Federation of Hemophilia.

Post-authorization pharmacovigilance for hemophilia in Europe and the USA: Independence and transparency are keys.

P. Mannucci, F. Peyvandi, I. Garagiola, 2021, Blood reviews.

Efficacy and safety of a recombinant factor VIII produced from a human cell line (simoctocog alfa)

M. Franchini, P. Mannucci, 2017, Expert opinion on drug safety.

The importance of ABO blood group in pharmacokinetic studies in haemophilia A

M. Franchini, P. Mannucci, S. Pupella, 2018, Haemophilia : the official journal of the World Federation of Hemophilia.

Response to "Innovation in Hemophilia Therapies-'And Miles to Go, before [We] Sleep'".

M. Franchini, P. Mannucci, 2016, Seminars in thrombosis and hemostasis.

Absence of clinical, virological, and immunological signs of progression in HIV-1-infected patients receiving active anti-interferon-alpha immunization: a 30-month follow-up report.

A. Burny, E. Santagostino, P. Mannucci, 1996, Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology.

Anti-alpha interferon immunization: safety and immunogenicity in asymptomatic HIV positive patients at high risk of disease progression.

E. Santagostino, P. Mannucci, A. Gringeri, 1995, Cellular and molecular biology.

A randomized, placebo-controlled, blind anti-AIDS clinical trial : safety and immunogenicity of a specific anti-IFNα immunization

A. Burny, E. Santagostino, P. Mannucci, 1994 .

Persistent Activation of Coagulation Mechanism in Unstable Angina and Myocardial Infarction

D. Ardissino, P. Mannucci, K. Bauer, 1994, Circulation.

Effects on bleeding complications of pharmacogenetic testing for initial dosing of vitamin K antagonists: a systematic review and meta‐analysis

M. Franchini, P. Mannucci, C. Mengoli, 2014, Journal of thrombosis and haemostasis : JTH.

Fibrotic interstitial lung diseases and air pollution: a systematic literature review

G. Raghu, S. Harari, M. Franchini, 2020, European Respiratory Review.

A prothrombin time-based functional assay of protein S.

P. Mannucci, A. Lombardi, A. Tripodi, 1990, Thrombosis research.

Suboptimal response to hepatitis B vaccine in drug users.

A. Zanetti, P. Mannucci, A. Boschini, 1991, Archives of internal medicine.

Immunogenicity of a yeast‐recombinant hepatitis B vaccine in high‐risk children

M. Colombo, P. Mannucci, A. Gringeri, 1989, Journal of medical virology.

Prevalence of pancreatic disorders in HIV-infected hemophiliacs: diagnostic methods and their clinical significance.

E. Santagostino, P. Mannucci, A. Gringeri, 1994, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Solvent/detergent plasma for prevention of bleeding in recessively inherited coagulation disorders: dosing, pharmacokinetics and clinical efficacy.

M. Morfini, E. Santagostino, P. Mannucci, 2006, Haematologica.

Serum hepatitis B virus DNA detects cryptic hepatitis B virus infections in multitransfused hemophilic patients

G. Colucci, P. Mannucci, A. Gringeri, 1990 .

Association of Anticholinergic Burden with Cognitive and Functional Status in a Cohort of Hospitalized Elderly: Comparison of the Anticholinergic Cognitive Burden Scale and Anticholinergic Risk Scale

A. Iorio, S. Corrao, M. Marcucci, 2013, Drugs & Aging.

HAEMOPHILIA CARE IN DEVELOPING COUNTRIES

P. Mannucci, 1980, The Lancet.

Identification of nine novel mutations in type I antithrombin deficiency by heteroduplex screening

S. Thein, P. Mannucci, K. Bauer, 1993, British journal of haematology.

Combined estrogen-progestin oral contraceptives [letter]

P. Mannucci, I. Martinelli, T. Battaglioli, 2004 .

Classic thrombophilic gene variants

M. Franchini, P. Mannucci, 2015, Thrombosis and Haemostasis.

Identification of genetic risk variants for deep vein thrombosis by multiplexed next-generation sequencing of 186 hemostatic/pro-inflammatory genes

R. Gibbs, D. Muzny, S. Scherer, 2012, BMC Medical Genomics.

Simultaneous genotyping of coagulation factor XI type II and type III mutations by multiplex real-time polymerase chain reaction to determine their prevalence in healthy and factor XI-deficient Italians

P. Mannucci, S. Duga, G. Castaman, 2008, Haematologica.

Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease

B. Giusti, O. Hummel, H. Schulz, 2016, Journal of the American Heart Association.

Reply to: Endogenous heparinoids contribute to coagulopathy in patients with liver disease

P. Mannucci, A. Tripodi, 2008 .

The coagulopathy of cirrhosis assessed by thromboelastometry and its correlation with conventional coagulation parameters.

P. Mannucci, A. Tripodi, V. Chantarangkul, 2008, Thrombosis research.

Clinical features and outcomes of elderly hospitalised patients with chronic obstructive pulmonary disease, heart failure or both

C. Mussi, L. Fenoglio, F. Dentali, 2023, Internal and Emergency Medicine.

Adverse clinical events and mortality during hospitalization and 3 months after discharge in cognitively impaired elderly patients.

A. Iorio, S. Corrao, M. Marcucci, 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

High levels of factor VIII and risk of extra-hepatic portal vein obstruction.

Paolo Bucciarelli, P. Mannucci, I. Martinelli, 2009, Journal of hepatology.

Afibrinogenemia: first identification of a splicing mutation in the fibrinogen gamma chain gene leading to a major gamma chain truncation

P. Giangrande, E. Santagostino, P. Mannucci, 2000 .

Primary Mantle Cell Lymphoma Cell Cultures Soluble Cd40 Ligand Induces Selective Proliferation of Lymphoma Cells In

P. Giangrande, E. Santagostino, P. Mannucci, 2022 .

Hypercoagulability in centenarians: the paradox of successful aging.

P M Mannucci, P. Mannucci, K. Bauer, 1995, Blood.

Pattern of comorbidities and 1-year mortality in elderly patients with COPD hospitalized in internal medicine wards: data from the RePoSI Registry

C. Mussi, L. Fenoglio, M. Barbagallo, 2020, Internal and Emergency Medicine.

Comorbidity does not mean clinical complexity: evidence from the RePoSI register

S. Corrao, A. Nobili, F. Perticone, 2019, Internal and Emergency Medicine.

Polypharmacy in older people: lessons from 10 years of experience with the REPOSI register

A. Nobili, P. Mannucci, L. Pasina, 2018, Internal and Emergency Medicine.

A factor V genetic component differing from factor V R506Q contributes to the activated protein C resistance phenotype

E. Sacchi, F. Bernardi, P. Mannucci, 1997 .

Embryo implantation after assisted reproductive procedures and maternal thrombophilia.

E. Taioli, P. Mannucci, I. Martinelli, 2003, Haematologica.

The risk of recurrent deep venous thrombosis among heterozygous carriers of both factor V Leiden and the G20210A prothrombin mutation.

G Leone, P M Mannucci, P. Chiusolo, 1999, The New England journal of medicine.

Vaccine-induced immune thrombotic thrombocytopenia with atypical vein thrombosis: Implications for clinical practice

P. Mannucci, F. Sessa, A. Scerrati, 2022, Phlebology.

Treatment of congenital antithrombin III deficiency with concentrates

P. Mannucci, M. Wolf, A. Tripodi, 1982, British journal of haematology.

Vascular And Platelet Effects Of Synthetic Analogues Of Prostacyclin

P. Mannucci, D. Mills, F. Pareti, 1981, Thrombosis and Haemostasis.

Coinheritance of the HR2 haplotype in the factor V gene confers an increased risk of venous thromboembolism to carriers of factor V R506Q (factor V Leiden).

M. Margaglione, P. Mannucci, V. De Stefano, 1999, Blood.

Fibrinogen Milano II: A Congenital Dysfibrinogenaemia Associated with Juvenile Arterial and Venous Thrombosis

P. Mannucci, C. Kluft, F. Haverkate, 1986, Thrombosis and Haemostasis.

Ischemic stroke in congenital (type II C) defective antithrombin III

M. Moia, A. Arbini, P. Mannucci, 1993, International journal of clinical & laboratory research.

Ticlopidine Facilitates the Deaggregation of Human Platelets Aggregated by Thrombin

C. Cimminiello, P. Mannucci, M. Packham, 1994, Thrombosis and Haemostasis.

Outcome of Treatment of Deep-Vein Thrombosis with Urokinase: Relationship to Dosage, Duration of Therapy, Age of the Thrombus and Laboratory Changes

P. Mannucci, A. D’Angelo, P. Mannucci, 1984, Thrombosis and Haemostasis.

Thrombin generation in plasma from patients with cirrhosis supplemented with normal plasma: considerations on the efficacy of treatment with fresh-frozen plasma

P. Mannucci, A. Aghemo, A. Tripodi, 2012, Internal and Emergency Medicine.

An imbalance of pro- vs anti-coagulation factors in plasma from patients with cirrhosis.

P. Mannucci, R. de Franchis, A. Tripodi, 2009, Gastroenterology.

THE PAST AS PROLOGUE — CIRRHOSIS AS THE EPITOME OF THE HEMORRHAGIC DISEASES ?

P. Mannucci, S. Caldwell, A. Tripodi, 2016 .

Multicenter evaluation of a new chromogenic factor X assay in plasma of patients on oral anticoagulants.

G. Gensini, G. Mariani, P. Mannucci, 1980, Thrombosis research.

A chromogenic assay of prothrombin compared with coagulation tests during anticoagulant therapy and liver disease

P. Mannucci, A. Tripodi, C. Santo, 1981, La Ricerca in clinica e in laboratorio.

High Levels of Tissue Factor Pathway Inhibitor in Patients with Nephrotic Proteinuria

C. Ponticelli, M. Moia, P. Mannucci, 1999, Thrombosis and Haemostasis.

No Evidence of Association Between Prothrombotic Gene Polymorphisms and the Development of Acute Myocardial Infarction at a Young Age

M. Margaglione, A. Piazza, L. Bernardinelli, 2003, Circulation.

Risk of venous thromboembolism after air travel: interaction with thrombophilia and oral contraceptives.

E. Taioli, P. Mannucci, I. Martinelli, 2003, Archives of internal medicine.

Familial dysfunctional protein C.

P. Mannucci, A. Tripodi, F. Franchi, 1986, Thrombosis research.

Familial Dysfunction of Protein S

P. Mannucci, E. Faioni, A. Tripodi, 1989, Thrombosis and Haemostasis.

[Hemostasis and liver disease].

P. Mannucci, D. Mari, 1981, Haematologica.

Congenital deficiencies of anticoagulant proteins (antithrombin III and protein C).

P. Mannucci, D. Mari, A. Tripodi, 1984, Haematologica.

National survey of human immunodeficiency virus infection in Italian hemophiliacs: 1983–1987

P. Mannucci, A. Gringeri, Medical-Scientific Committee of the Fondazione dell’Emofilia, 1988, La Ricerca in clinica e in laboratorio.

Atypical hemolytic uremic syndrome (aHUS): essential aspects of an accurate diagnosis.

M. Nangaku, S. Rodríguez de Córdoba, H. Haller, 2016, Clinical advances in hematology & oncology : H&O.

TT virus is present in a high frequency of Italian hemophilic patients transfused with plasma-derived clotting factor concentrates.

P. Mannucci, D. Prati, Y. H. Lin, 1999, Blood.

Convalescent plasma for administration of passive antibodies against viral agents

P. Mannucci, J. Ironside, G. Di Minno, 2020, Haematologica.

Premature termination codon mutations in the von Willebrand factor gene are associated with allele-specific and position-dependent mRNA decay

P. Mannucci, S. Duga, M. Platé, 2010, Haematologica.

Adherence to antithrombotic therapy guidelines improves mortality among elderly patients with atrial fibrillation: insights from the REPOSI study

G. Lip, A. Nobili, P. Mannucci, 2016, Clinical Research in Cardiology.

Oral anticoagulant use in octogenarian European patients with atrial fibrillation: A subanalysis of PREFER in AF.

P. Kirchhof, R. de Caterina, J. Le Heuzey, 2017, International journal of cardiology.

Long-Term Relationship Between Atrial Fibrillation, Multimorbidity and Oral Anticoagulant Drug Use.

G. Lip, G. Boriani, M. Roncaglioni, 2019, Mayo Clinic proceedings.

Joint use of cardio-embolic and bleeding risk scores in elderly patients with atrial fibrillation.

A. Iorio, S. Corrao, M. Marcucci, 2013, European journal of internal medicine.

Cholesterol-adjusted vitamin E serum levels are associated with cardiovascular events in patients with non-valvular atrial fibrillation.

A. Farcomeni, G. Davı̀, G. Corazza, 2013, International journal of cardiology.

New drugs for thromboprophylaxis in atrial fibrillation.

S. Garattini, A. Nobili, P. Mannucci, 2012, European journal of internal medicine.

The natural history of hepatitis C virus infection in Italian patients with von Willebrand's disease: a cohort study.

E. Santagostino, P. Mannucci, A. Federici, 2006, Haematologica.

P. Pontisso, M. Morfini, E. Santagostino, 1997, Blood.

A 6-month versus a 12-month surveillance for hepatocellular carcinoma in 559 hemophiliacs infected with the hepatitis C virus.

E. Santagostino, P. Mannucci, A. Rocino, 2003, Blood.

Liver transplantation in severe von Willebrand disease

P. Mannucci, A. Federici, M. Cattaneo, 1991, The Lancet.

Hemophilia [4] (multiple letters)

R. Merion, G. Mariani, P. Mannucci, 2001 .

Mitigation of air pollution by greenness: A narrative review.

M. Franchini, P. Mannucci, 2018, European journal of internal medicine.

Health Effects of Ambient Air Pollution in Developing Countries

M. Franchini, P. Mannucci, 2017, International journal of environmental research and public health.

Why so many different specialty training programmes in general practice in Europe?

A. Nobili, P. Mannucci, L. Garattini, 2022, Internal and Emergency Medicine.

Acute promyelocytic leukemia with unusual morphological features, absence of the t(15,17) and rearranged PML/RAR alpha genes.

P. Mannucci, A. Cortelezzi, A. Federici, 1994, Haematologica.

Prognostic value of estimated glomerular filtration rate in hospitalized elderly patients

S. Corrao, M. Marcucci, A. Nobili, 2014, Internal and Emergency Medicine.

Polypharmacy, length of hospital stay, and in-hospital mortality among elderly patients in internal medicine wards. The REPOSI study

Salvatore Corrao, Alessandra Marengoni, Giuseppe Licata, 2011, European Journal of Clinical Pharmacology.

Antibodies to factor VIII-von Willebrand factor in congenital and acquired von Willebrand's disease.

P. Mannucci, D. Mari, 1984, Progress in clinical and biological research.

Acquired coagulation disorders: revisited using global coagulation/anticoagulation testing

P. Mannucci, A. Tripodi, V. Chantarangkul, 2009, British journal of haematology.

Prognostic relevance of glomerular filtration rate estimation obtained through different equations in hospitalized elderly patients.

A. Nobili, P. Mannucci, P. Gallo, 2018, European journal of internal medicine.

Von Willebrand Disease Type 2M “Vicenza” in Italian and German Patients: Identification of the First Candidate Mutation (G3864A; R1205H) in 8 Families

P. Mannucci, P. Mannucci, F. Rodeghiero, 2000, Thrombosis and Haemostasis.

Fibrinogen assays: a collaborative study of six different methods. C.I.S.M.E.L. Comitato Italiano per la Standardizzazione dei Metodi in Ematologia e Laboratorio.

P. Mannucci, G. Palareti, F. Rodeghiero, 1991, Clinical chemistry.

EVALUATION OF A FULLY AUTOMATED CENTRIFUGAL ANALYSER FOR ITS PERFORMANCE OF HEMOSTASIS TESTS

V Chantarangkul, A Tripodi, P M Mannucci, 1987, Thrombosis and Haemostasis.

Assessment of a new instrument (Coag-A-Mate X2) for performing global clotting tests and specific factor assays.

P. Mannucci, A. Tripodi, M. Cugno, 1985, Clinical and laboratory haematology.

Genome-Wide Association Studies in Myocardial Infarction and Coronary Artery Disease

P. Mannucci, F. Peyvandi, L. Lotta, 2010, The journal of Tehran Heart Center.

Value of Hu antibody determinations in the follow-up of paraneoplastic neurologic syndromes

J. Delattre, P. Mannucci, Y. Blanco, 2004, Neurology.

Apolipoprotein(a) Kringle-IV Type 2 Copy Number Variation Is Associated with Venous Thromboembolism

B. Giusti, R. Abbate, A. Magi, 2016, PloS one.

Few platelets, many platelets: the role of the internist

P. Mannucci, Pier Mannuccio Mannucci, 2000 .

Circulating microparticles and risk of venous thromboembolism.

P. Mannucci, I. Martinelli, P. Bucciarelli, 2009, Thrombosis research.

Antibodies to tissue-type plasminogen activator (tPA) in patients with antiphospholipid syndrome: evidence of interaction between the antibodies and the catalytic domain of tPA in 2 patients.

R. Russo, P. Mannucci, P. Meroni, 2004, Blood.

Molecular basis of fibrinogen Naples associated with defective thrombin binding and thrombophilia. Homozygous substitution of B beta 68 Ala----Thr.

S. Lord, P. Mannucci, J. Grimbergen, 1992, The Journal of clinical investigation.

Effects of PCSK9 genetic variants on plasma LDL cholesterol levels and risk of premature myocardial infarction in the Italian population

S. Kathiresan, D. Ardissino, I. Guella, 2010, Journal of Lipid Research.

Coagulation activation and long-term outcome in acute coronary syndromes Running title: Coagulation activation and long-term outcome in CHD Section heading: Clinical observation

D. Ardissino, P. Mannucci, M. Galvani, 2003 .

Coagulation activation and long-term outcome in acute coronary syndromes.

D. Ardissino, P. Mannucci, M. Galvani, 2003, Blood.

In Vivo Thrombin Generation and Activity During and After Intravenous Infusion of Heparin or Recombinant Hirudin in Patients With Unstable Angina Pectoris

D. Ardissino, P. Mannucci, M. Galvani, 2000, Arteriosclerosis, thrombosis, and vascular biology.

CYP2C9 genotypes and dose requirements during the induction phase of oral anticoagulant therapy

M. Moia, P. Mannucci, F. Peyvandi, 2004, Clinical pharmacology and therapeutics.

Impact of Diabetes Mellitus and Its Comorbidities on Elderly Patients Hospitalized in Internal Medicine Wards: Data from the RePoSi Registry

S. Corrao, A. Nobili, F. Perticone, 2022, Healthcare.

Molecular Mapping of the Chloride-binding Site in von Willebrand Factor (VWF)

P. Mannucci, A. Federici, R. De Cristofaro, 2006, Journal of Biological Chemistry.

Particulate Air Pollution and Cardiovascular Risk: Short-term and Long-term Effects

M. Franchini, P. Mannucci, Pier Mannucci2, 2009, Seminars in thrombosis and hemostasis.

Mechanistic studies on ADAMTS13 catalysis.

P. Mannucci, R. De Cristofaro, F. Peyvandi, 2008, Biophysical journal.

Role of Chloride Ions in Modulation of the Interaction between von Willebrand Factor and ADAMTS-13*

P. Mannucci, R. De Cristofaro, F. Peyvandi, 2005, Journal of Biological Chemistry.

The real value of thrombophilia markers in identifying patients at high risk of venous thromboembolism

M. Franchini, P. Mannucci, 2014, Expert review of hematology.

Comparison of Health Care Resource Utilization by Immigrants Versus Native Elderly People

M. Roncaglioni, A. Nobili, P. Mannucci, 2016, Journal of Immigrant and Minority Health.

The role of general practitioners in the EU: time to draw lessons from a too wide range?

A. Nobili, P. Mannucci, L. Garattini, 2023, Internal and Emergency Medicine.

Hospital Care of Older Patients With COPD: Adherence to International Guidelines for Use of Inhaled Bronchodilators and Corticosteroids.

C. Mussi, L. Fenoglio, M. Barbagallo, 2019, Journal of the American Medical Directors Association.

Gender difference in drug use in hospitalized elderly patients.

S. Corrao, M. Marcucci, P. Santalucia, 2015, European journal of internal medicine.

Activation of the Protein C Pathway in Hereditary Thrombophilia

P. Mannucci, P. Mannucci, E. Faioni, 1998, Thrombosis and Haemostasis.

Familial aggregation of early-onset myocardial infarction.

L. Bernardinelli, D. Ardissino, V. Cipriani, 2010, European journal of internal medicine.

Sex-Differences in the Pattern of Comorbidities, Functional Independence, and Mortality in Elderly Inpatients: Evidence from the RePoSI Register

G. Corazza, S. Corrao, A. Nobili, 2019, Journal of clinical medicine.

Myocardial infarction in the young: a sex-based comparison

L. Foco, P. Mannucci, M. Ferlini, 2007, Coronary artery disease.

Oral contraceptive use, thrombophilia and their interaction in young women with ischemic stroke.

P. Mannucci, I. Martinelli, T. Battaglioli, 2006, Haematologica.

Association between air temperature, air pollution and hospital admissions for pulmonary embolism and venous thrombosis in Italy.

M. Stafoggia, F. Forastiere, M. Davoli, 2021, European journal of internal medicine.

Germinal Matrix Hemorrhage: Intraventricular Hemorrhage in Very-Low-Birth-Weight Infants The Independent Role of Inherited Thrombophilia

D. Consonni, P. Bertazzi, L. Ramenghi, 2011, Stroke.

Prophylaxis of venous thromboembolism in elderly patients with multimorbidity

A. Iorio, S. Corrao, M. Marcucci, 2013, Internal and Emergency Medicine.

Prophylaxis of venous thromboembolism in elderly patients with multimorbidity Maura MarcucciAlfonso IorioAlessandro NobiliMauro TettamantiLuca PasinaCodjo Djignefa Djade • Alessandra MarengoniFrancesco SalernoSalvatore CorraoPier Mannuccio Mannucci • REPOSI (REgistro POliterapie SocietaItaliana di M

A. Iorio, S. Corrao, M. Marcucci, 2013 .

Low borderline plasma levels of antithrombin, protein C and protein S are risk factors for venous thromboembolism

P. Mannucci, I. Martinelli, P. Bucciarelli, 2012, Journal of thrombosis and haemostasis : JTH.

Recurrent Late Fetal Death in Women with and without Thrombophilia

E. Taioli, I. Cetin, P. Mannucci, 2002, Thrombosis and Haemostasis.

Comparison of quality of life, and emotional and functional profiles in older people with and without severe haemophilia

A. Iorio, E. Santagostino, P. Mannucci, 2021, Haemophilia : the official journal of the World Federation of Hemophilia.

ADAMTS13 autoantibodies in patients with thrombotic microangiopathies and other immunomediated diseases.

B. Lämmle, G. Remuzzi, P. Mannucci, 2005, Blood.

Living Near Major Traffic Roads and Risk of Deep Vein Thrombosis

Paolo Grillo, Antonella Zanobetti, Joel Schwartz, 2009, Circulation.

Air Pollution, Smoking, and Plasma Homocysteine

J. Schwartz, L. Hou, A. Baccarelli, 2006, Environmental health perspectives.

The stigma of low opioid prescription in the hospitalized multimorbid elderly in Italy

S. Corrao, M. Marcucci, A. Nobili, 2015, Internal and Emergency Medicine.

Living Near Major Traffic Roads and Risk of Deep Vein Thrombosis

Paolo Grillo, Steven J. Melly, Antonella Zanobetti, 2009, Circulation.

Novel evidence for a greater burden of ambient air pollution on cardiovascular disease

S. Harari, M. Franchini, P. Mannucci, 2019, Haematologica.

Exposure to particulate air pollution and risk of deep vein thrombosis.

J. Schwartz, L. Hou, A. Baccarelli, 2008, Archives of internal medicine.

Common variants in the haemostatic gene pathway contribute to risk of early-onset myocardial infarction in the Italian population

Flora Peyvandi, Diego Ardissino, Stefano Duga, 2011, Thrombosis and Haemostasis.

Particulate matter phagocytosis induces tissue factor in differentiating macrophages

V. Bollati, P. Bertazzi, F. Colombo, 2016, Journal of applied toxicology : JAT.

Initiation of Psycholeptic Medication During Hospitalization With Recommendation for Discontinuation After Discharge.

M. Cesari, D. Consonni, A. Nobili, 2020, Journal of the American Medical Directors Association.

Time to face the challenge of multimorbidity. A European perspective from the joint action on chronic diseases and promoting healthy ageing across the life cycle (JA-CHRODIS).

G. Onder, K. Palmer, P. Mannucci, 2015, European journal of internal medicine.

Low Plasma Levels of Vitamin B6 Are Independently Associated With a Heightened Risk of Deep-Vein Thrombosis

P. Mannucci, P. Bucciarelli, M. Cattaneo, 2001, Circulation.

Different Quantitative Apoptotic Traits in Coronary Atherosclerotic Plaques From Patients With Stable Angina Pectoris and Acute Coronary Syndromes

E. Bramucci, D. Ardissino, P. Mannucci, 2004, Circulation.

A Proposed Scheme for Calibration of International Reference Preparations of Thromboplastin for the Prothrombin Time

P. Mannucci, L. Poller, A. Tripodi, 1995, Thrombosis and Haemostasis.

Calibration of Local Systems with Lyophilized Calibrant Plasmas Improves the Interlaboratory Variability of the INR in the Italian External Quality Assessment Scheme

P. Mannucci, A. Tripodi, V. Chantarangkul, 1999, Thrombosis and Haemostasis.

Heparin in pregnant women with previous placenta-mediated pregnancy complications: a prospective, randomized, multicenter, controlled clinical trial.

G. Remuzzi, G. Pardi, P. Ruggenenti, 2012, Blood.

Molecular Characterisation and Three-Dimensional Structural Analysis of Mutations in 21 Unrelated Families with Inherited Factor VII Deficiency

S. Perkins, P. Mannucci, S. Zeinali, 2000, Thrombosis and Haemostasis.

Homozygous 2bp Deletion in the Human Factor VII Gene: A Non-Lethal Mutation that Is Associated with a Complete Absence of Circulating Factor VII

P. Mannucci, F. Peyvandi, R. Coppola, 2000, Thrombosis and Haemostasis.

Near‐patient testing devices to monitor oral anticoagulant therapy

P. Mannucci, A. Tripodi, V. Chantarangkul, 2001, British journal of haematology.

Adherence to antibiotic treatment guidelines and outcomes in the hospitalized elderly with different types of pneumonia.

S. Corrao, M. Marcucci, A. Nobili, 2015, European journal of internal medicine.

Drug-drug interactions involving CYP3A4 and p-glycoprotein in hospitalized elderly patients.

A. Nobili, P. Mannucci, P. Gallo, 2019, European journal of internal medicine.

Risk factors for postpartum hemorrhage in a cohort of 6011 Italian women.

P. Mannucci, F. Ambrogi, E. Biganzoli, 2012, Thrombosis research.

Evolution of the European guidelines for the clinical development of factor VIII products: little progress towards improved patient management

P. Mannucci, P. Mannucci, 2013, Haemophilia : the official journal of the World Federation of Hemophilia.

Two Naturally Occurring Mutations on FVII Gene (S363I-W364C) Altering Intrinsic Catalytic Activity

P. Mannucci, K. Bauer, R. De Cristofaro, 2002, Thrombosis and Haemostasis.

The P303T mutation in the human factor VII (FVII) gene alters the conformational state of the enzyme and causes a severe functional deficiency

P. Mannucci, F. Peyvandi, I. Garagiola, 2004, British journal of haematology.

Low-Dose Heparin and Deep-Vein Thrombosis after Total Hip Replacement

P. Mannucci, N. Panajotopoulos, Luisa Citterio, 1976, Thrombosis and Haemostasis.

The international normalized ratio to prioritize patients for liver transplantation: problems and possible solutions.

P. Mannucci, A. Tripodi, V. Chantarangkul, 2008, Journal of thrombosis and haemostasis : JTH.

Multicentric Evaluation of a New PT Reagent Based on Recombinant Human Tissue Factor and Synthetic Phospholipids

J. Hirsh, P. Mannucci, A. Tripodi, 1994, Thrombosis and Haemostasis.

More on air pollution and venous thromboembolism.

M. Franchini, P. Mannucci, 2017, European journal of internal medicine.

The multifaceted spectrum of liver cirrhosis in older hospitalised patients: analysis of the REPOSI registry.

A. Nobili, P. Mannucci, L. Cortesi, 2020, Age and ageing.

Imatinib and polypharmacy in very old patients with chronic myeloid leukemia: effects on response rate, toxicity and outcome

R. Latagliata, G. Rosti, P. Vigneri, 2016, Oncotarget.

Early-onset ischaemic stroke: Analysis of 58 polymorphisms in 17 genes involved in methionine metabolism

B. Giusti, R. Abbate, A. Magi, 2010, Thrombosis and Haemostasis.

Drug–drug interactions in a cohort of hospitalized elderly patients

A. Iorio, S. Corrao, M. Marcucci, 2013, Pharmacoepidemiology and drug safety.

Association between clusters of diseases and polypharmacy in hospitalized elderly patients: results from the REPOSI study.

A. Iorio, S. Corrao, M. Marcucci, 2011, European journal of internal medicine.

Gout, allopurinol intake and clinical outcomes in the hospitalized multimorbid elderly.

S. Corrao, M. Marcucci, A. Nobili, 2014, European journal of internal medicine.

Risk factors for hospital readmission of elderly patients.

Salvatore Corrao, Daniela Mari, Alessandra Marengoni, 2013, European journal of internal medicine.

Internal and geriatric medicine: an alliance for the challenges of the elderly.

A. Nobili, P. Mannucci, 2012, European journal of internal medicine.

Identification of four novel polymorphisms in the Aalpha and gamma fibrinogen genes and analysis of association with plasma levels of the protein.

P. Mannucci, P. Bucciarelli, S. Duga, 2001, Thrombosis research.

Attitudes towards polypharmacy and medication withdrawal among older inpatients in Italy

Maura Lusignani, Emily Reeve, A. Nobili, 2016, International Journal of Clinical Pharmacy.

Potentially Inappropriate Medications, Drug–Drug Interactions, and Anticholinergic Burden in Elderly Hospitalized Patients: Does an Association Exist with Post-Discharge Health Outcomes?

A. Nobili, P. Mannucci, R. Antonelli Incalzi, 2020, Drugs & Aging.

Additional genetic risk factors for venous thromboembolismin carriers of the factor V Leiden mutation

P. Chiusolo, P. Mannucci, A. Tosetto, 1998, British journal of haematology.

Marburg I polymorphism of factor VII-activating protease and risk of venous thromboembolism.

P. Mannucci, I. Martinelli, P. Bucciarelli, 2006, Blood.

Underdiagnosis and undertreatment of osteoporotic patients admitted in internal medicine wards in Italy between 2010 and 2016 (the REPOSI Register)

C. Mussi, L. Fenoglio, M. Barbagallo, 2021, Endocrine.

Antipsychotic prescription and mortality in hospitalized older persons

S. Corrao, M. Marcucci, A. Nobili, 2017, Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society.

Appropriateness of antiplatelet therapy for primary and secondary cardio‐ and cerebrovascular prevention in acutely hospitalized older people

A. Nobili, P. Mannucci, F. Peyvandi, 2017, British journal of clinical pharmacology.

Hyperglycemia at admission, comorbidities, and in-hospital mortality in elderly patients hospitalized in internal medicine wards: data from the RePoSI Registry

C. Mussi, L. Fenoglio, M. Barbagallo, 2021, Acta Diabetologica.

Risk factors for three-month mortality after discharge in a cohort of non-oncologic hospitalized elderly patients: Results from the REPOSI study.

A. Nobili, P. Mannucci, L. Cortesi, 2018, Archives of gerontology and geriatrics.

Clinical factors associated with death in 3044 COVID-19 patients managed in internal medicine wards in Italy: comment

D. Girelli, G. Grasselli, A. Pesenti, 2021, Internal and Emergency Medicine.

Clinical and laboratory observations in eight patients with lupus-type circulating anticoagulant.

P. Mannucci, M. Cattaneo, M. Canciani, 1979, Haematologica.

A common mutation in the methylenetetrahydrofolate reductase gene (C677T) increases the risk for deep-vein thrombosis in patients with mutant factor V (factor V:Q506).

P. Mannucci, E. Taioli, P. Mannucci, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Psychological impact of thrombosis in the young

P. Mannucci, I. Martinelli, P. Bucciarelli, 2006, Internal and emergency medicine.

Relation between drug therapy-based comorbidity indices, Charlson's comorbidity index, polypharmacy and mortality in three samples of older adults.

A. Nobili, P. Mannucci, M. Tettamanti, 2022, Archives of gerontology and geriatrics.

Comparison between drug therapy-based comorbidity indices and the Charlson Comorbidity Index for the detection of severe multimorbidity in older subjects

A. Nobili, P. Mannucci, M. Tettamanti, 2020, Aging Clinical and Experimental Research.

Pain and Frailty in Hospitalized Older Adults

C. Mussi, L. Fenoglio, M. Barbagallo, 2020, Pain and Therapy.

Determination of total homocysteine in plasma: comparison of the Abbott IMx immunoassay with high performance liquid chromatography.

P. Mannucci, M. Cattaneo, A. Tripodi, 2002, Haematologica.

Point-of-care coagulation monitors calibrated for the international normalized ratio for cirrhosis (INRliver) can help to implement the INRliver for the calculation of the MELD score.

P. Mannucci, F. Iannuzzi, A. Aghemo, 2009, Journal of hepatology.

Inhibitors of factor VIII in hemophilia.

P. Mannucci, F. Peyvandi, L. Lotta, 2009, New England Journal of Medicine.

Identification of genetic risk variants for deep vein thrombosis by multiplexed next-generation sequencing of 186 hemostatic/pro-inflammatory genes

R. Gibbs, D. Muzny, S. Scherer, 2012, BMC Medical Genomics.

The association of factor V Leiden with myocardial infarction is replicated in 1880 patients with premature disease

S. Kathiresan, D. Ardissino, P. Mannucci, 2010, Journal of thrombosis and haemostasis : JTH.

Implementation of the Frailty Index in hospitalized older patients: Results from the REPOSI register.

M. Cesari, A. Nobili, P. Mannucci, 2018, European journal of internal medicine.

Prevalence of HTLV‐IIVLAV antibodies in Italian asymptomatic hemophiliacs given commercial concentrates of factors VIII and IX

F. Mandelli, G. Mariani, P. Mannucci, 1986, Journal of medical virology.

Use of Lipid-Lowering Drugs and Associated Outcomes According to Health State Profiles in Hospitalized Older Patients

A. Nobili, P. Mannucci, C. Franchi, 2021, Clinical interventions in aging.

The international normalized ratio to prioritize patients for liver transplantation: problems and possible solutions

P. Mannucci, A. Tripodi, V. Chantarangkul, 2008 .

Antidiabetic Drug Prescription Pattern in Hospitalized Older Patients with Diabetes

A. Nobili, P. Mannucci, C. Franchi, 2023, International journal of environmental research and public health.

ABO blood group and venous thromboembolism a ) Single studies

M. Franchini, P. Mannucci, 2017 .

Hemostatic Functions in Hypoalpha and Hyperbetalipoproteinemias

P. Mannucci, C. Vergani, P. Mannucci, 1983, Thrombosis and Haemostasis.

Pharmaceutical patenting in the European Union: reform or riddance

P. Mannucci, L. Garattini, M. Badinella Martini, 2021, Internal and Emergency Medicine.

Association and Functional Analyses of MEF2A as a Susceptibility Gene for Premature Myocardial Infarction and Coronary Artery Disease

D. Girelli, N. Martinelli, D. Ardissino, 2009, Circulation. Cardiovascular genetics.

Sustainable nutrition and the case of vegetable oils to match present and future dietary needs

O. Jolliet, A. Aleta, Y. Moreno, 2023, Frontiers in Public Health.

The incidence of venous thromboembolism in asymptomatic carriers of antithrombin, protein C or protein S: a prospective cohort study.

P. Prandoni, M. Moia, P. Wells, 1999 .

Specificity of hepatitis C antibody ELISA in patients with haemophilia

P. Mannucci, M. Colombo, M. Rumi, 1990, The Lancet.

Thrombotic thrombocytopenic purpura and other immune-mediated blood disorders following vaccination against SARS-CoV-2

P. Mannucci, 2021, Haematologica.

Protein S Deficiency Associated with “Juvenile” Arterial and Venous Thromboses

R. Bertina, P. Mannucci, A. Tripodi, 1986, Thrombosis and Haemostasis.

Effects of CYP2C9 and VKORC1 on INR variations and dose requirements during initial phase of anticoagulant therapy.

F. Rosendaal, P. Mannucci, C. Lodigiani, 2008, Pharmacogenomics (London).

expression of the recombinant protein moderately severe factor V deficiency: molecular characterization by Arg2074Cys missense mutation in the C2 domain of factor V causing

E. Santagostino, P. Mannucci, S. Duga, 2013 .

Community and hospital pharmacists in Europe: encroaching on medicine?

P. Mannucci, L. Garattini, A. Padula, 2020, Internal and Emergency Medicine.

A Simplified Procedure for Thromboplastin Calibration -The Usefulness of Lyophilized Plasmas Assessed in a Collaborative Study

P. Mannucci, P. Bucciarelli, A. Tripodi, 1996, Thrombosis and Haemostasis.

A partial factor V deficiency in anticoagulated lyophilized plasmas has been identified as a cause of the international normalized ratio discrepancy in the external quality assessment scheme.

P. Mannucci, A. Tripodi, V. Chantarangkul, 1995, Thrombosis Research.

Successful Calibration of a Reagent from Human Placenta against rTF/95, the WHO International Reference Preparation for Thromboplastin, Human Recombinant, Plain

P. Mannucci, A. Tripodi, V. Chantarangkul, 1998, Thrombosis and Haemostasis.

Occult Cancer and Venous Thromboembolism

M. Moia, P. Mannucci, P. Bucciarelli, 1998, Thrombosis and Haemostasis.

Prescription appropriateness of anticoagulant drugs for prophylaxis of venous thromboembolism in hospitalized multimorbid older patients

A. Nobili, P. Mannucci, F. Peyvandi, 2022, Internal and Emergency Medicine.

Molecular Characterization of a Multiethnic Group of 21 Patients with Type 3 von Willebrand Disease

P. Mannucci, P. Mannucci, A. Federici, 2000, Thrombosis and Haemostasis.

ASIC — LIVER , PANCREAS , AND BILIARY RACT n Imbalance of Pro-vs AntiCoagulation Factors in Plasma From atients With Cirrhosis

P. Mannucci, R. Franchis, M. Colombo, 2022 .

Pattern of in‐hospital changes in drug use in the older people from 2010 to 2016

A. Nobili, F. Perticone, P. Mannucci, 2017, Pharmacoepidemiology and drug safety.

Therapeutic Duplicates in a Cohort of Hospitalized Elderly Patients: Results from the REPOSI Study

A. Nobili, P. Mannucci, L. Cortesi, 2016, Drugs & Aging.

Predictors of clinical events occurring during hospital stay among elderly patients admitted to medical wards in Italy.

D. Mari, D. Consonni, M. Marcucci, 2016, European journal of internal medicine.

The Health and Economic Burden of Air Pollution.

Federico Pontoni, S. Harari, M. Franchini, 2015, The American journal of medicine.

Post-COVID condition: dispensation of drugs and diagnostic tests as proxies of healthcare impact

B. D'avanzo, G. Remuzzi, S. Harari, 2023, Internal and Emergency Medicine.

Reply to the letter by Iorio

F. Rosendaal, P. Mannucci, F. Peyvandi, 2017, Haemophilia : the official journal of the World Federation of Hemophilia.

Inflammatory and prothrombotic parameters in normotensive non-diabetic obese women: effect of weight loss obtained by gastric banding

D. Mari, P. Mannucci, M. Zappa, 2012, Internal and Emergency Medicine.

The genetic basis of coronary artery disease: from candidate genes to whole genome analysis.

Flora Peyvandi, Massimo Franchini, M. Franchini, 2008, Trends in cardiovascular medicine.

ACUTE PROMYELOCYTIC LEUKEMIA WITH UNUSUAL MORPHOLOGICAL FEATURES , ABSENCE OF THE t ( 15 , 17 ) AND REARRANGED PML / RAR a GENES

P. Mannucci, A. Cortelezzi, A. Federici, 2005 .

The significance of protein C antigen in acute and chronic liver biliary disease.

P. Mannucci, P. Mannucci, A. D’Angelo, 1985, American journal of clinical pathology.

Witnessing the 1980s

P. Mannucci, 2020, Haemophilia.

Reply: Interaction between inherited thrombophilia and HIV infection: fact or fancy?

P. Mannucci, I. Martinelli, V. Stefano, 2014, Nature Reviews Cardiology.

Does enhancement of oxidative stress markers mediate health effects of ambient air particles?

V. Bollati, M. Bonzini, P. Bertazzi, 2014, Antioxidants and Redox Signaling.

Correction to: Hyperglycemia at admission, comorbidities, and in-hospital mortality in elderly patients hospitalized in internal medicine wards: data from the RePoSI Registry

S. Corrao, A. Nobili, F. Perticone, 2021, Acta Diabetologica.

Disability, and not diabetes, is a strong predictor of mortality in oldest old patients hospitalized with pneumonia.

G. Corazza, S. Corrao, A. Nobili, 2018, European journal of internal medicine.

Bleeding events in people with congenital haemophilia A without factor VIII inhibitors receiving prophylactic factor VIII treatment: A systematic literature review

R. Ofori-Asenso, A. Iorio, F. Germini, 2023, Haemophilia : the official journal of the World Federation of Hemophilia.

Heterogeneity of type I von Willebrand disease: evidence for a subgroup with an abnormal von Willebrand factor.

G. Mariani, P. Mannucci, A. Federici, 1985, Blood.

A randomized clinical trial of prophylaxis in children with hemophilia A (the ESPRIT Study)

L. Mantovani, P. Mannucci, A. Gringeri, 2011, Journal of thrombosis and haemostasis : JTH.

Improving primary care in Europe beyond COVID-19: from telemedicine to organizational reforms

P. Mannucci, L. Garattini, M. Badinella Martini, 2020, Internal and Emergency Medicine.

High risk of cerebral-vein thrombosis in carriers of a prothrombin-gene mutation and in users of oral contraceptives.

E. Sacchi, E. Taioli, P. Mannucci, 1998, The New England journal of medicine.

How we manage cardiovascular disease in patients with hemophilia

M. Franchini, P. Mannucci, D. Focosi, 2023, Haematologica.

Studies of the pathophysiology of acquired von Willebrand's disease in seven patients with lymphoproliferative disorders or benign monoclonal gammopathies.

P. Mannucci, P. Mannucci, G. Finazzi, 1984, Blood.

282 HIGH INCIDENCE OF HEPARIN INDUCED THROMBOCYTOPENIA (HIT) IN SPLANCHNIC VEIN THROMBOSIS TREATED WITH LOW MOLECULAR WEIGHT HEPARIN (LMWH)

P. Mannucci, A. Artoni, M. Primignani, 2008 .

Prevalence of potentially inappropriate medications and risk of adverse clinical outcome in a cohort of hospitalized elderly patients: results from the REPOSI Study

S. Corrao, M. Marcucci, A. Nobili, 2014, Journal of clinical pharmacy and therapeutics.

Choice and Outcomes of Rate Control versus Rhythm Control in Elderly Patients with Atrial Fibrillation: A Report from the REPOSI Study

G. Lip, A. Nobili, P. Mannucci, 2018, Drugs & Aging.

Risk of cerebral vein thrombosis and oral contraceptives

E. Taioli, P. Mannucci, I. Martinelli, 1998, The Lancet.

Haematology clinic: Haemophilia A

M. Franchini, P. Mannucci, 2014, Hematology.

Sharing data of clinical trials.

P. Mannucci, 2016, European journal of internal medicine.

Health technology assessment for pharmaceuticals in the European Union: what lessons after two decades?

A. Nobili, P. Mannucci, L. Garattini, 2022, Internal and Emergency Medicine.

Conjugated estrogens for the management of bleeding associated with renal failure.

G. Remuzzi, P. Mannucci, P. Mannucci, 1986, The New England journal of medicine.

Bleeding and thrombosis in 55 patients with inherited afibrinogenaemia

P. Mannucci, F. Peyvandi, Mannucci, 1999, British journal of haematology.

Molecular basis of von Willebrand disease type IIB. Candidate mutations cluster in one disulfide loop between proposed platelet glycoprotein Ib binding sequences.

P. Mannucci, P. Mannucci, D. Mancuso, 1991, The Journal of clinical investigation.

Congenital afibrinogenemia: intracellular retention of fibrinogen due to a novel W437G mutation in the fibrinogen Bbeta-chain gene.

P. Mannucci, S. Duga, F. Peyvandi, 2003, Biochimica et biophysica acta.

Opposite changes of ADAMTS‐13 and von Willebrand factor after cardiac surgery

P. Mannucci, M. Camera, A. Parolari, 2005, Journal of thrombosis and haemostasis : JTH.

Activation of the coagulation cascade in C1-inhibitor deficiencies.

P. Mannucci, M. Cicardi, P. Mannucci, 1997, Blood.

Risk Factors for Recurrence of Thrombotic Thrombocytopenic Purpura.

F. Fabris, P. Mannucci, T. Battaglioli, 2006 .

Defensive medicine: Everything and its opposite.

P. Mannucci, L. Garattini, A. Padula, 2020, European journal of internal medicine.

Deamino-8-D-arginine vasopressin shortens the bleeding time in uremia.

G. Remuzzi, P. Mannucci, P. Mannucci, 1983, The New England journal of medicine.

Prothrombotic genetic risk factors in young survivors of myocardial infarction.

M. Margaglione, D. Ardissino, P. Mannucci, 1999, Blood.

Congenital factor X deficiency: spectrum of bleeding symptoms in 32 Iranian patients

P. Mannucci, S. Zeinali, F. Peyvandi, 1998, British journal of haematology.

High prevalence of hyperhomocyst(e)inemia in patients with juvenile venous thrombosis.

P. Mannucci, I. Martinelli, P. Mannucci, 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.

DEVELOPMENT AND MORPHOLOGY OF THE SKULL IN THE DIK-DIKS (GENUS MADOQUA OGILBY, ARTIODACTYLA BOVIDAE)

P. Mannucci, A. Simonetta, M. Poggesi, 1982 .

The natural mutation by deletion of Lys9 in the thrombin A‐chain affects the pKa value of catalytic residues, the overall enzyme's stability and conformational transitions linked to Na+ binding

P. Mannucci, F. Peyvandi, R. Palla, 2006, The FEBS journal.

A Natural Prothrombin Mutant Reveals an Unexpected Influence of A-chain Structure on the Activity of Human α-Thrombin*

P. Mannucci, R. De Cristofaro, F. Peyvandi, 2004, Journal of Biological Chemistry.

The risk of recurrent venous thromboembolism among heterozygous carriers of the G20210A prothrombin gene mutation.

G Leone, P M Mannucci, P. Chiusolo, 2001, British journal of haematology.

Standardization of the APC Resistance Test. Effects of Normalization of Results by Means of Pooled Normal Plasma

P. Mannucci, A. Tripodi, V. Chantarangkul, 1998, Thrombosis and Haemostasis.

Quality assurance program for whole blood prothrombin time-international normalized ratio point-of-care monitors used for patient self-testing to control oral anticoagulation.

P. Mannucci, A. Tripodi, M. Carpenedo, 2004, Thrombosis research.

Abstract 4011: Influence Of Rs1333040, A Newly Discovered 9p21.3 Genetic Variant, On Clinical Outcomes In Early-onset Myocardial Infarction

L. Bernardinelli, D. Ardissino, L. Foco, 2008 .

A novel polymorphism in intron 1a of the human factor VII gene (G73A): study of a healthy Italian population and of 190 young survivors of myocardial infarction

Sacchi, E. Sacchi, P. Mannucci, 2000, British journal of haematology.

Asymptomatic homozygous protein C deficiency.

P. Mannucci, A. Tripodi, F. Franchi, 1990, Acta Haematologica.

Clinical efficacy of simoctocog alfa versus extended half‐life recombinant FVIII concentrates in hemophilia A patients undergoing personalized prophylaxis using a matching‐adjusted indirect comparison method

V. Jiménez‐Yuste, C. Kessler, P. Mannucci, 2023, European journal of haematology.

Prospective study of hepatitis after factor VIII concentrate exposed to hot vapour

A. Zanetti, P. Mannucci, P. Mannucci, 1988, British journal of haematology.

Re: "Validated questionnaire for the identification of previous personal or familial venous thromboembolism".

E. Taioli, V. Rossi, P. Mannucci, 1998, American journal of epidemiology.

Risk Factors and Recurrence Rate of Primary Deep Vein Thrombosis of the Upper Extremities

G. Moneta, P. Mannucci, I. Martinelli, 2006 .

Blood Coagulation , Fibrinolysis and Cellular Haemostasis Early-onset ischaemic stroke : Analysis of 58 polymorphisms in 17 genes involved in methionine metabolism

B. Giusti, R. Abbate, A. Magi, 2018 .

Early-onset ischaemic stroke: Analysis of 58 polymorphisms in 17 genes involved in methionine metabolism

B. Giusti, R. Abbate, A. Magi, 2010, Thrombosis and Haemostasis.

Two years of SARS-CoV-2 pandemic and COVID-19 in Lombardy, Italy

B. D'avanzo, G. Remuzzi, S. Harari, 2023, Internal and Emergency Medicine.

Relationship between atrial fibrillation and cognitive decline in individuals aged 80 and older.

A. Nobili, P. Mannucci, E. Riva, 2017, European journal of internal medicine.

Post-recovery impact of the second and third SARS-CoV-2 infection waves on healthcare resource utilization in Lombardy, Italy.

B. D'avanzo, G. Remuzzi, S. Harari, 2023, Internal and emergency medicine.

Short-term Exposure to High Altitude Causes Coagulation Activation and Inhibits Fibrinolysis

P. Mannucci, G. Mariani, P. Mannucci, 2002, Thrombosis and Haemostasis.

Functional Assays of Protein C: Comparison of Two Snake-Venom Assays with Two Thrombin Assays

P. Mannucci, A. Tripodi, C. Valsecchi, 1988, Thrombosis and Haemostasis.

Time to face the challenge of multimorbidity. A European perspective from the joint action on chronic diseases and promoting healthy ageing across the life cycle (JA-CHRODIS).

G. Onder, K. Palmer, P. Mannucci, 2015, European journal of internal medicine.

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

Joshua M. Korn, Benjamin J. Wright, P. Deloukas, 2009, Nature Genetics.

Expert position paper on air pollution and cardiovascular disease.

O. Franco, A. Baccarelli, R. Brook, 2015, European heart journal.

The real value of thrombophilia markers in identifying patients at high risk of venous thromboembolism

M. Franchini, P. Mannucci, 2014, Expert review of hematology.

Use of non-steroidal anti-inflammatory drugs and analgesics in a cohort of hospitalized elderly patients: Results from the REPOSI study.

A. Nobili, P. Mannucci, L. Cortesi, 2017, European journal of internal medicine.

Coronary Heart Disease / Myocardial Infarction Diminished Vascular Response to Inhibition of Endothelium-Derived Nitric Oxide and Enhanced Vasoconstriction to Exogenously Administered Endothelin-1 in Clinically Healthy Smokers

Samin K. Sharma, R. Califf, Jeffrey L. Anderson, 2005 .

Uncertain thrombophilia markers

M. Franchini, P. Mannucci, I. Martinelli, 2016, Thrombosis and Haemostasis.

Living Near Major Traffic Roads and Risk of Deep Vein Thrombosis

J. Schwartz, L. Hou, A. Baccarelli, 2009, Circulation.

Co‐morbidities and quality of life in elderly persons with haemophilia

M. Franchini, P. Mannucci, 2010, British journal of haematology.

How I treat rare venous thromboses.

M. Franchini, P. Mannucci, I. Martinelli, 2008, Blood.

Authors’ Reply to Brunetti et al. “Potentially Inappropriate Medications, Drug–Drug Interactions, and Anticholinergic Burden in Elderly Hospitalized Patients: Does an Association Exist with Post-Discharge Health Outcomes?”

A. Nobili, P. Mannucci, R. Antonelli Incalzi, 2020, Drugs & Aging.

Pharmacist-driven medication recognition/ reconciliation in older medical patients.

A. Nobili, P. Mannucci, L. Cortesi, 2020, European journal of internal medicine.

Cholesterol-adjusted vitamin E serum levels are associated with cardiovascular events in patients with non-valvular atrial fibrillation.

A. Farcomeni, G. Davı̀, G. Corazza, 2013, International journal of cardiology.

Hyperprothrombinemia may result in scquired activated protein C reistance.

P. Mannucci, A. Tripodi, V. Chantarangkul, 2000, Blood.

Tailoring hemostatic therapies to lower inhibitor development in previously untreated patients with severe hemophilia A

P. Mannucci, M. Franchini, P. Mannucci, 2016, Journal of thrombosis and haemostasis : JTH.

The Health and Economic Burden of Air Pollution.

Federico Pontoni, S. Harari, M. Franchini, 2015, The American journal of medicine.

E-learning in order to improve drug prescription for hospitalized older patients: a cluster-randomized controlled study.

G. Onder, S. Bonassi, A. Nobili, 2016, British journal of clinical pharmacology.

Adjunct agents for bleeding

M. Franchini, P. Mannucci, 2014, Current opinion in hematology.

Incidence of severe von Willebrand's disease.

P. Mannucci, Weiss Hj, Ball Ap, 1982 .

A clinicopathological study of liver disease in haemophiliacs.

P. Mannucci, P. Mannucci, M. Colombo, 1978, Journal of clinical pathology.

Factor V (Arg 506-->Gln) mutation in young survivors of myocardial infarction.

D. Ardissino, P. Mannucci, P. Merlini, 1996, Thrombosis and haemostasis.

The role of natural VWF/FVIII complex concentrates in contemporary haemophilia care: a guideline for the next decade

P. Mannucci, P. Mannucci, 2012, Haemophilia : the official journal of the World Federation of Hemophilia.

Thrombotic risk factors: Basic pathophysiology

P. Mannucci, I. Martinelli, P. Bucciarelli, 2010, Critical care medicine.

Antihypertensive treatment changes and related clinical outcomes in older hospitalized patients

A. Nobili, P. Mannucci, V. Zaccone, 2022, European journal of clinical investigation.

Randomized double-blind, placebo-controlled trial of twice-daily zidovudine in asymptomatic haemophiliacs infected with the human immunodeficiency virus type 1. European-Australian Haemophilia Collaborative Study Group.

P. Mannucci, A. Gringeri, Y. Laurian, 1994, British journal of haematology.

The search of a common path in internal medicine.

P. Mannucci, E. Bartoli, 2012, European journal of internal medicine.

Making clinical decisions on the basis of RODIN

P. Mannucci, 2014, Haemophilia : the official journal of the World Federation of Hemophilia.

Hemophilia A in the third millennium.

M. Franchini, P. Mannucci, 2013, Blood reviews.

Laboratory Diagnosis of Lupus Anticoagulants

P. Mannucci, A. Tripodi, V. Chantarangkul, 2002, Thrombosis and Haemostasis.

Adherence to antithrombotic therapy guidelines improves mortality among elderly patients with atrial fibrillation: insights from the REPOSI study

G. Lip, A. Nobili, P. Mannucci, 2016, Clinical Research in Cardiology.

Monitoring Warfarin Therapy in Patients with Lupus Anticoagulants (LA)

P. Mannucci, A. Tripodi, 1998, Thrombosis and Haemostasis.

Patient preferences and willingness to pay for different options of anticoagulant therapy

G. Cesana, L. Mantovani, M. Moia, 2013, Internal and Emergency Medicine.