J. Spafford

发表

Justin R. Davis, R. L. Davis, M. G. Ciufolini, 2009, Encyclopedia of Neuroscience.

Eukaryotic Voltage-Gated Sodium Channels: On Their Origins, Asymmetries, Losses, Diversification and Adaptations

J. Spafford, J. Moffat, J. Fux, 2018, Front. Physiol..

Calmodulin regulates Cav3 T-type channels at their gating brake

A. Dolphin, T. Dieckmann, J. Spafford, 2017, The Journal of Biological Chemistry.

G-proteins modulate invertebrate synaptic calcium channel (LCav2) differently from the classical voltage-dependent regulation of mammalian Cav2.1 and Cav2.2 channels

A. Senatore, J. Spafford, Xuan Huang, 2010, Journal of Experimental Biology.

Determinants of Inhibition of Transiently Expressed Voltage-gated Calcium Channels by ω-Conotoxins GVIA and MVIIA*

Aaron M. Beedle, Zhong-Ping Feng, J. Spafford, 2003, Journal of Biological Chemistry.

PKC-Induced Intracellular Trafficking of CaV2 Precedes Its Rapid Recruitment to the Plasma Membrane

L. Kaczmarek, A. Senatore, J. Spafford, 2008, The Journal of Neuroscience.

Gd3+ and Calcium Sensitive, Sodium Leak Currents Are Features of Weak Membrane-Glass Seals in Patch Clamp Recordings

A. Senatore, J. Spafford, A. Boone, 2014, PloS one.

Molecular determinants of Rem2 regulation of N-type calcium channels.

J. Spafford, S. Hameed, G. Zamponi, 2008, Biochemical and biophysical research communications.

Asynchronous Delivery of a 400 Level, Partially Peer-Graded, Oral Presentation and Discussion Course in Systems Neuroscience for 60 Students during the COVID-19 Pandemic

J. Spafford, J. Moffat, Charlotte Copas, 2021, Brain sciences.

Cav3 T-type channels as drug targets for treating epilepsy

J. Spafford, W. Guan, R. Stephens, 2014 .

Selectivity filters and cysteine-rich extracellular loops in voltage-gated sodium, calcium, and NALCN channels

J. Spafford, W. Guan, B. Zhorov, 2015, Front. Physiol..

A uniquely adaptable pore is consistent with NALCN being an ion sensor

A. Senatore, J. Spafford, 2013, Channels.

NALCN Ion Channels Have Alternative Selectivity Filters Resembling Calcium Channels or Sodium Channels

A. Smit, A. Senatore, J. Spafford, 2013, PloS one.

Gene Splicing of an Invertebrate Beta Subunit (LCavβ) in the N-Terminal and HOOK Domains and Its Regulation of LCav1 and LCav2 Calcium Channels

A. Senatore, J. Spafford, A. Boone, 2014, PloS one.

A lysine residue from an extracellular turret switches the ion preference in a Cav3 T-Type channel from calcium to sodium ions

J. Spafford, W. Guan, B. Zhorov, 2022, bioRxiv.

Expression and Modulation of an Invertebrate Presynaptic Calcium Channel α1 Subunit Homolog*

A. Smit, Zhong-Ping Feng, J. Spafford, 2003, Journal of Biological Chemistry.

Calcium Channel Structural Determinants of Synaptic Transmission between Identified Invertebrate Neurons*

A. Smit, N. Syed, D. Munno, 2003, The Journal of Biological Chemistry.

A putative voltage-gated sodium channel alpha subunit (PpSCN1) from the hydrozoan jellyfish, Polyorchis penicillatus: structural comparisons and evolutionary considerations.

J. Spafford, W. Gallin, A. Spencer, 1998, Biochemical and biophysical research communications.

Cav3 T-type channels: regulators for gating, membrane expression, and cation selectivity

A. Senatore, J. Spafford, W. Guan, 2014, Pflügers Archiv - European Journal of Physiology.

A cardiac-like sodium current in motor neurons of a jellyfish.

J. Spafford, N. Grigoriev, A. Spencer, 1996, Journal of neurophysiology.

The Calmodulin-Binding, Short Linear Motif, NSCaTE Is Conserved in L-Type Channel Ancestors of Vertebrate Cav1.2 and Cav1.3 Channels

A. Senatore, J. Spafford, A. Boone, 2013, PloS one.

Identification and Functional Expression of a Family of Nicotinic Acetylcholine Receptor Subunits in the Central Nervous System of the Mollusc Lymnaea stagnalis*

D. Bertrand, A. Smit, N. Syed, 2006, Journal of Biological Chemistry.

Cav3 T‐type calcium channels

A. Senatore, J. Spafford, B. Zhorov, 2012 .

Gene Transcription and Splicing of T-Type Channels Are Evolutionarily-Conserved Strategies for Regulating Channel Expression and Gating

A. Senatore, J. Spafford, 2012, PloS one.

Ca v 3 T-type calcium channels

A. Senatore, J. Spafford, B. Zhorov, 2012 .

Calcium-triggered Membrane Fusion Proceeds Independently of Specific Presynaptic Proteins*

J. Coorssen, J. Spafford, G. Wessel, 2003, Journal of Biological Chemistry.

Residues in a jellyfish shaker-like channel involved in modulation by external potassium.

J. Spafford, N. Grigoriev, A. Spencer, 1999, Journal of neurophysiology.

in Modulation by External Potassium -Like Channel Involved Shaker Residues in a Jellyfish

G. Bett, J. Spafford, V. Bondarenko, 2015 .

Functional interactions between presynaptic calcium channels and the neurotransmitter release machinery

J. Spafford, G. Zamponi, 2003, Current Opinion in Neurobiology.

Voltage sensing in jellyfish Shaker K+ channels.

J. Spafford, W. Gallin, N. Grigoriev, 1997, The Journal of experimental biology.

T-type Channels Become Highly Permeable to Sodium Ions Using an Alternative Extracellular Turret Region (S5-P) Outside the Selectivity Filter*♦

A. Senatore, J. Spafford, A. Boone, 2014, The Journal of Biological Chemistry.

Extracellular Turret Region ( S 5P ) Outside to Sodium Ions Using an Alternative T-type Channels Become Highly Permeable Molecular Biophysics

A. Senatore, J. Spafford, A. Boone, 2014 .

A governance of ion selectivity based on the occupancy of the “beacon” in one- and four-domain calcium and sodium channels

J. Spafford, 2023, Channels.

Calcium Channels: Regulation of Gene Transcription

A. Senatore, J. Spafford, 2008 .

Genomic organization of a voltage-gated Na+ channel in a hydrozoan jellyfish: insights into the evolution of voltage-gated Na+ channel genes.

J. Spafford, W. Gallin, A. Spencer, 1999, Receptors & channels.

The effects of level of expression of a jellyfish Shaker potassium channel: a positive potassium feedback mechanism

J. Spafford, N. Grigoriev, A. Spencer, 1999, The Journal of physiology.

In vitro characterization of L-type calcium channels and their contribution to firing behavior in invertebrate respiratory neurons.

A. Smit, N. Syed, T. Dunn, 2006, Journal of neurophysiology.

An ancestral maguk protein supports the modulation of mammalian voltage-gated Ca2+ channels through a conserved CaVβ-like interface.

R. Sauvé, J. Spafford, Amrit Mehta, 2020, Biochimica et biophysica acta. Biomembranes.

Unique cysteine-enriched, D2L5 and D4L6 extracellular loops in CaV3 T-type channels alter the passage and block of monovalent and divalent ions

J. Spafford, J. Fux, Amrit Mehta, 2020, Scientific Reports.

Uncoupling of Calcium Channel α1 and β Subunits in Developing Neurons*

A. Smit, N. Syed, J. Spafford, 2004, Journal of Biological Chemistry.

Modulation of jellyfish potassium channels by external potassium ions.

J. Spafford, N. Grigoriev, A. Spencer, 1999, Journal of neurophysiology.

External Potassium Ions Modulation of Jellyfish Potassium Channels by

J. Spafford, W. Gallin, N. Grigoriev, 2015 .

Uncoupling of Calcium Channel α1 and β Subunits in Developing Neurons*

J. Spafford, G. Zamponi, Naweed I. Syed, 2004, Journal of Biological Chemistry.

Cav3 T-type channels: regulators for gating, membrane expression, and cation selectivity

A. Senatore, J. Spafford, W. Guan, 2014, Pflügers Archiv - European Journal of Physiology.