G. Amidon

发表

Measurement of fasted state gastric antral motility before and after a standard bioavailability and bioequivalence 240 mL drink of water: Validation of MRI method against concomitant perfused manometry in healthy participants

Jason R. Baker, L. Marciani, R. Spiller, 2020, PloS one.

Printing of small molecular medicines from the vapor phase

Roy Clarke, Max Shtein, Geeta Mehta, 2017, Nature Communications.

Drug Marker Absorption in Relation to Pellet Size, Gastric Motility and Viscous Meals in Humans

Jeremy J. Frens, G. Amidon, G. Amidon, 1998, Pharmaceutical Research.

Particle size limits to meet USP content uniformity criteria for tablets and capsules.

G. Amidon, B. Rohrs, R. Meury, 2006, Journal of pharmaceutical sciences.

The Biopharmaceutics Classification System: subclasses for in vivo predictive dissolution (IPD) methodology and IVIVC.

G. Amidon, D. Mudie, G. Amidon, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Quantification of gastrointestinal liquid volumes and distribution following a 240 mL dose of water in the fasted state.

Martin C Garnett, Luca Marciani, Gordon L Amidon, 2014, Molecular pharmaceutics.

A modified Drucker-Prager Cap model for die compaction simulation of pharmaceutical powders

Lianghao Han, Bruno C. Hancock, James A. Elliott, 2008 .

Chapter 8 – Particle, Powder, and Compact Characterization

D. Mudie, G. Amidon, P. J. Secreast, 2009 .

Particle, Powder, and Compact Characterization

Gregory E. Amidon, D. Mudie, G. Amidon, 2009 .

Factors that influence the spontaneous formation of pharmaceutical cocrystals by simply mixing solid reactants

Naír Rodríguez-Hornedo, Gregory E. Amidon, Chinmay Maheshwari, 2009 .

Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties

Christel A. S. Bergström, D. Mudie, G. Amidon, 2020, The AAPS Journal.

In vivo predictive dissolution: transport analysis of the CO2 , bicarbonate in vivo buffer system.

G. Amidon, G. Amidon, S. Taghavi, 2014, Journal of pharmaceutical sciences.

Physicochemical Characterization and Oral Dosage Form Selection Based on the Biopharmaceutics Classification System

Xiaorong He, G. Amidon, M. Hageman, 2010 .

Physicochemical Characterization and Principles of Oral Dosage Form Selection

Xiaorong He, G. Amidon, M. Hageman, 2003 .

Application of the Gastrointestinal Simulator (GIS) Coupled with In Silico Modeling to Measure the Impact of Coca-Cola® on the Luminal and Systemic Behavior of Loratadine (BCS Class 2b)

G. Amidon, M. Bermejo, B. Hens, 2020, Pharmaceutics.

Physiological parameters for oral delivery and in vitro testing.

G. Amidon, D. Mudie, G. Amidon, 2010, Molecular pharmaceutics.

In vitro dissolution methodology, mini-Gastrointestinal Simulator (mGIS), predicts better in vivo dissolution of a weak base drug, dasatinib.

G. Amidon, G. Amidon, K. Matsui, 2015, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Magnetic Resonance Imaging Quantification of Fasted State Colonic Liquid Pockets in Healthy Humans.

L. Marciani, R. Spiller, G. Amidon, 2017, Molecular pharmaceutics.

The in vivo predictive dissolution for immediate release dosage of donepezil and danazol, BCS class IIc drugs, with the GIS and the USP II with biphasic dissolution apparatus

G. Amidon, G. Amidon, H. Ruan, 2020 .

Summary of the In Vivo Predictive Dissolution (iPD) - Oral Drug Delivery (ODD) Conference 2018

R. Ziff, L. Marciani, R. Löbenberg, 2018 .

Evaluation of a three compartment in vitro gastrointestinal simulator dissolution apparatus to predict in vivo dissolution.

Yasuhiro Tsume, Gordon L Amidon, G. Amidon, 2014, Journal of pharmaceutical sciences.

An In Vivo Predictive Dissolution Methodology (iPD Methodology) with a BCS Class IIb Drug Can Predict the In Vivo Bioequivalence Results: Etoricoxib Products

G. Amidon, M. Bermejo, B. Hens, 2021, Pharmaceutics.

The Combination of GIS and Biphasic to Better Predict In Vivo Dissolution of BCS Class IIb Drugs, Ketoconazole and Raloxifene.

G. Amidon, G. Amidon, Y. Tsume, 2018, Journal of pharmaceutical sciences.

In Vivo Predictive Dissolution and Simulation Workshop Report: Facilitating the Development of Oral Drug Formulation and the Prediction of Oral Bioperformance

G. Amidon, J. Brasseur, M. Bermejo, 2018, The AAPS Journal.

Theoretical and experimental studies of transport of micelle-solubilized solutes.

G. Amidon, W. Higuchi, N. Ho, 1982, Journal of pharmaceutical sciences.

Mechanistic analysis and experimental verification of bicarbonate‐controlled enteric coat dissolution: Potential in vivo implications

G. Amidon, M. Bermejo, G. Amidon, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Evaluating the IVIVC by Combining Tiny-TIM Outputs and Compartmental PK Model to Predict Oral Exposure for Different Formulations of Ibuprofen.

G. Amidon, K. Nagapudi, Jia Liu, 2022, Journal of pharmaceutical sciences.

Dissolution Challenges Associated with the Surface pH of Drug Particles: Integration into Mechanistic Oral Absorption Modeling

G. Amidon, M. Bermejo, B. Hens, 2022, The AAPS Journal.

Mass Transport Analysis of Bicarbonate Buffer: Effect of the CO2-H2CO3 Hydration-Dehydration Kinetics in the Fluid Boundary Layer and the Apparent Effective p Ka Controlling Dissolution of Acids and Bases.

R. Ziff, G. Amidon, G. Amidon, 2019, Molecular pharmaceutics.

Mass Transport Analysis of the Enhanced Buffer Capacity of the Bicarbonate-CO2 Buffer in a Phase-Heterogenous System: Physiological and Pharmaceutical Significance.

G. Amidon, M. Bermejo, B. Hens, 2018, Molecular pharmaceutics.

Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs.

Kerby Shedden, Jianghong Fan, Marival Bermejo, 2017, Molecular pharmaceutics.

Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 2: Fed State.

Jason R. Baker, R. Löbenberg, G. Amidon, 2018, Molecular pharmaceutics.

Some hydrodynamic boundary layer influences on mass transfer coefficients

G. Flynn, E. Williams, G. Amidon, 1984 .

The Effect of Moisture on the Mechanical and Powder Flow Properties of Microcrystalline Cellulose

M. E. Houghton, G. Amidon, 1995, Pharmaceutical Research.

Predicted absorption rates with simultaneous bulk fluid flow in the intestinal tract.

G. Amidon, W. Higuchi, N. Ho, 1981, Journal of theoretical biology.

Rotary press utilizing a flexible die wall.

G. Amidon, D. P. Smith, E. Hiestand, 1981, Journal of pharmaceutical sciences.

Mechanistic Analysis of Cocrystal Dissolution, Surface pH, and Dissolution Advantage as a Guide for Rational Selection.

N. Rodríguez-Hornedo, G. Amidon, Fengjuan Cao, 2019, Journal of pharmaceutical sciences.

The solubility-permeability interplay: mechanistic modeling and predictive application of the impact of micellar solubilization on intestinal permeation.

G. Amidon, G. Amidon, A. Dahan, 2011, Molecular pharmaceutics.

The solubility-permeability interplay in using cyclodextrins as pharmaceutical solubilizers: mechanistic modeling and application to progesterone.

Gordon L Amidon, Arik Dahan, G. Amidon, 2010, Journal of pharmaceutical sciences.

The Evaluation of In Vitro Drug Dissolution of Commercially Available Oral Dosage Forms for Itraconazole in Gastrointestinal Simulator With Biorelevant Media.

G. Amidon, G. Amidon, K. Matsui, 2016, Journal of pharmaceutical sciences.

Fifty-Eight Years and Counting: High-Impact Publishing in Computational Pharmaceutical Sciences and Mechanism-Based Modeling.

Shiew-Mei Huang, Filippos Kesisoglou, Johannes G Khinast, 2019, Journal of pharmaceutical sciences.

The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system: Gastrointestinal Simulator (GIS)

Kazuki Matsui, Yasuhiro Tsume, Gordon L Amidon, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro‐in silico‐in vivo approach

Marival Bermejo, Bart Hens, Gregory E. Amidon, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Understanding Pharmaceutical Quality by Design

G. K. Raju, Lawrence X. Yu, Mansoor A. Khan, 2014, The AAPS Journal.

Improving Dissolution Behavior and Oral Absorption of Drugs with pH-Dependent Solubility Using pH Modifiers: A Physiologically Realistic Mass Transport Analysis.

R. Ziff, G. Amidon, G. Amidon, 2021, Molecular pharmaceutics.

In Vitro-In Vivo Correlation in Cocrystal Dissolution: Consideration of Drug Release Profiles Based on Coformer Dissolution and Absorption Behavior.

G. Amidon, M. Kataoka, S. Yamashita, 2021, Molecular pharmaceutics.

Evaluation of the effects of tableting speed on the relationships between compaction pressure, tablet tensile strength, and tablet solid fraction.

Changquan Calvin Sun, G. Amidon, Gregory E Amidon, 2005, Journal of pharmaceutical sciences.

Use of Gastrointestinal Simulator, Mass Transport Analysis, and Absorption Simulation to Investigate the Impact of pH Modifiers in Mitigating Weakly Basic Drugs' Performance Issues Related to Gastric pH: Palbociclib Case Study.

G. Amidon, G. Kuminek, David C. Sperry, 2022, Molecular pharmaceutics.

The impact of hot melt extrusion and spray drying on mechanical properties and tableting indices of materials used in pharmaceutical development.

G. Amidon, James C Dinunzio, A. Malick, 2013, Journal of pharmaceutical sciences.

Effect of spray-dried particle morphology on mechanical and flow properties of felodipine in PVP VA amorphous solid dispersions.

G. Amidon, Aaron K. Goodwin, D. Malewski, 2019, Journal of pharmaceutical sciences.

In Vivo Predictive Dissolution and Simulation Workshop Report: Facilitating the Development of Oral Drug Formulation and the Prediction of Oral Bioperformance

G. Amidon, J. Brasseur, M. Bermejo, 2018, The AAPS Journal.

Determination of the sensitivity of a tablet formulation to variations in excipient levels and processing conditions using optimization techniques

G. Amidon, Christopher F. Dick, R. A. Klassen, 1987 .

Exploring Bioequivalence of Dexketoprofen Trometamol Drug Products with the Gastrointestinal Simulator (GIS) and Precipitation Pathways Analyses

G. Amidon, M. Bermejo, N. Rodríguez-Hornedo, 2019, Pharmaceutics.

8th IAPC Meeting : : Book of Abstracts

E. Giovannetti, N. Funel, G. Peters, 2017 .

Characterization of Synthesized and Commercial Forms of Magnesium Stearate Using Differential Scanning Calorimetry, Thermogravimetric Analysis, Powder X-Ray Diffraction, and Solid-State NMR Spectroscopy.

E. Munson, G. Amidon, M. Sethi, 2017, Journal of pharmaceutical sciences.

Physical and Mechanical Property Characterization of Powders

G. Amidon, 1995 .

Physicochemical Characterization and Oral Dosage Form Design and Selection

Michael J. Hageman, Gregory E. Amidon, Tahnee J. Dening, 2021, Burger's Medicinal Chemistry and Drug Discovery.

Reducing the time to develop and manufacture formulations forfirst oral dose in humans

Madhusudan Hariharan, D GanorkarLoksidh, Gregory E. Amidon, 2003 .

Advancing Product Quality: a Summary of the Second FDA/PQRI Conference

G. K. Raju, Lawrence X. Yu, Larisa C Wu, 2016, The AAPS Journal.

Mechanistic analysis of solute transport in an in vitro physiological two‐phase dissolution apparatus

G. Amidon, G. Amidon, Yi Shi, 2012, Biopharmaceutics & drug disposition.

Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 1: Fasted State Conditions.

Katie L. Cavanagh, Jason R. Baker, R. Löbenberg, 2018, Molecular pharmaceutics.

Microscopic Characterization of Particle Size and Shape: An Inexpensive and Versatile Method

Gregory E. Amidon, Michael E. Houghton, M. E. Houghton, 1992, Pharmaceutical Research.

Printing of small molecular medicines from the vapor phase

Christina M. Jones, R. Clarke, P. Sinko, 2017, Nature Communications.

Mechanistic Basis of Cocrystal Dissolution Advantage.

G. Amidon, N. Rodríguez-Hornedo, G. Amidon, 2018, Journal of pharmaceutical sciences.

In Vivo Predictive Dissolution: Comparing the Effect of Bicarbonate and Phosphate Buffer on the Dissolution of Weak Acids and Weak Bases.

Gordon L Amidon, G. Amidon, G. Amidon, 2015, Journal of pharmaceutical sciences.

Formulation predictive dissolution (fPD) testing to advance oral drug product development: An introduction to the US FDA funded '21st Century BA/BE' project.

James G Brasseur, Kerby Shedden, Niloufar Salehi, 2018, International journal of pharmaceutics.

Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi‐compartment stomach approach

Jason R. Baker, R. Löbenberg, G. Amidon, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Mechanistic study of the effect of roller compaction and lubricant on tablet mechanical strength.

Xiaorong He, Xiaorong He, G. Amidon, 2007, Journal of pharmaceutical sciences.

Mechanistic Analysis of Cocrystal Dissolution as a Function of pH and Micellar Solubilization

G. Amidon, N. Rodríguez-Hornedo, G. Amidon, 2016, Molecular pharmaceutics.

Application of powder X-ray diffraction in studying the compaction behavior of bulk pharmaceutical powders.

G. Amidon, M. Hawley, J. Selbo, 2005, Journal of pharmaceutical sciences.

In Vitro Characterization of the Biomimetic Properties of Poly(dimethylsiloxane) To Simulate Oral Drug Absorption.

P. Sinko, G. Amidon, G. Amidon, 2017, Molecular pharmaceutics.

In Vitro Dissolution of Fluconazole and Dipyridamole in Gastrointestinal Simulator (GIS), Predicting in Vivo Dissolution and Drug-Drug Interaction Caused by Acid-Reducing Agents.

Kazuki Matsui, Yasuhiro Tsume, G. Amidon, 2015, Molecular pharmaceutics.

In Vitro Dissolution of Fluconazole and Dipyridamole in Gastrointestinal Simulator (GIS), Predicting in Vivo Dissolution and Drug-Drug Interaction Caused by Acid-Reducing Agents.

G. Amidon, G. Amidon, K. Matsui, 2015, Molecular pharmaceutics.