C. Yannopoulos

发表

Identification of N,N-disubstituted phenylalanines as a novel class of inhibitors of hepatitis C NS5B polymerase.

Darius Bilimoria, Lucille L'Heureux, R. Bethell, 2003, Journal of medicinal chemistry.

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: tertiary amides.

Denis Labrecque, Darius Bilimoria, R. Bethell, 2004 .

Incidental catch and estimated discards of pelagic sharks from the swordfish and tuna fisheries in the Mediterranean Sea

C. Yannopoulos, D. Macías, D. Damalas, 2005 .

Structural basis for the RNA binding selectivity of oligonucleotide analogues containing alkylsulfide internucleoside linkages and 2'-substituted 3'-deoxyribonucleosides.

C. Yannopoulos, M. Damha, G. Just, 1995, Nucleic acids research.

Synthesis of antisense oligonucleotides conjugated to a multivalent carbohydrate cluster for cellular targeting.

M. Manoharan, V. Mohan, C. Yannopoulos, 2003, Bioconjugate chemistry.

The differential regulation by glucagon and growth hormone of insulin-like growth factor (IGF)-I and IGF binding proteins in cultured rat hepatocytes.

B. Posner, C. Yannopoulos, I. Barash, 1991, Endocrinology.

Design and synthesis of a potent macrocyclic 1,6-naphthyridine anti-human cytomegalovirus (HCMV) inhibitors.

L. Chan, C. Yannopoulos, J. Bédard, 2005, Bioorganic & medicinal chemistry letters.

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: tertiary amides.

Darius Bilimoria, Lucille L'Heureux, R. Bethell, 2004, Bioorganic & medicinal chemistry letters.

Non-nucleoside Analogue Inhibitors Bind to an Allosteric Site on HCV NS5B Polymerase

Meitian Wang, M. James, K. Ng, 2003, The Journal of Biological Chemistry.

Discovery of Novel Thiophene-Based, Thumb Pocket 2 Allosteric Inhibitors of the Hepatitis C NS5B Polymerase with Improved Potency and Physicochemical Profiles.

B. G. Rao, G. Iyer, L. Chan, 2016, Journal of medicinal chemistry.

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides.

Denis Labrecque, Darius Bilimoria, Lucille L'Heureux, 2004, Bioorganic & medicinal chemistry letters.

Non-nucleoside inhibitors binding to hepatitis C virus NS5B polymerase reveal a novel mechanism of inhibition.

Meitian Wang, Darius Bilimoria, M. James, 2006, Journal of molecular biology.

Crystal Structures of the RNA-dependent RNA Polymerase Genotype 2a of Hepatitis C Virus Reveal Two Conformations and Suggest Mechanisms of Inhibition by Non-nucleoside Inhibitors*

Meitian Wang, Darius Bilimoria, M. James, 2005, Journal of Biological Chemistry.

Further SAR studies on novel small molecule inhibitors of the hepatitis C (HCV) NS5B polymerase.

L. Chan, M. Proulx, S. Das, 2003, Bioorganic & medicinal chemistry letters.

HCV NS5B polymerase-bound conformation of a soluble sulfonamide inhibitor by 2D transferred NOESY.

F. Ni, R. Bethell, L. Chan, 2004, Bioorganic & medicinal chemistry letters.

Movements and migrations of North Atlantic Bluefin tuna tagged with pop-up satellite tags

J. L. Cort, C. Yannopoulos, M. Pappalepore, 2007 .

Docking Ligands into Flexible and Solvated Macromolecules. 2. Development and Application of Fitted 1.5 to the Virtual Screening of Potential HCV Polymerase Inhibitors

Christopher R. Corbeil, Nicolas Moitessier, Pablo Englebienne, 2008, J. Chem. Inf. Model..

Discovery of Novel Thiophene-Based, Thumb Pocket 2 Allosteric Inhibitors of the Hepatitis C NS5B Polymerase with Improved Potency and Physicochemical Profiles.

G. Iyer, L. Chan, C. Yannopoulos, 2016, Journal of medicinal chemistry.

Benzimidazole-containing HCV NS5A inhibitors: effect of 4-substituted pyrrolidines in balancing genotype 1a and 1b potency.

L. Chan, S. Das, Oswy Z. Pereira, 2015, Bioorganic & medicinal chemistry letters.