D. Labrecque

发表

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: tertiary amides.

Denis Labrecque, Darius Bilimoria, R. Bethell, 2004 .

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 7- and 5-, 6-, 8-positions.

William E. Kemnitzer, H. Gourdeau, S. Kasibhatla, 2005, Bioorganic & medicinal chemistry letters.

Discovery of spirofused piperazine and diazepane amides as selective histamine-3 antagonists with in vivo efficacy in a mouse model of cognition.

D. Labrecque, P. Bernstein, Dean G. Brown, 2014, Journal of medicinal chemistry.

Antivascular and antitumor evaluation of 2-amino-4-(3-bromo-4,5-dimethoxy-phenyl)-3-cyano-4H-chromenes, a novel series of anticancer agents.

H. Gourdeau, S. Kasibhatla, L. Geerts, 2004, Molecular cancer therapeutics.

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based HTS assay. Part 5: modifications of the 2- and 3-positions.

William E. Kemnitzer, H. Gourdeau, S. Kasibhatla, 2008, Bioorganic & medicinal chemistry letters.

Enantioselective total synthesis of salicylihalamides A and B

D. Labrecque, S. Lamothe, S. Charron, 2001 .

Stereoselective reactions of α-silylallyl anions with carbonyl compounds.

D. Labrecque, T. Chan, 1992 .

1‐(Trimethylsilyl)vinyllithium

D. Labrecque, T. Chan, 2001 .

(1‐Bromovinyl)trimethylsilane

D. Labrecque, T. Chan, 2001 .

Synthesis of (aminomethyl)silanes with the use of an easily cleavable carbon-silicon bond

K. T. Nwe, D. Labrecque, T. Chan, 1994 .

A novel regioselective synthesis of allylsilanes

D. Labrecque, T. Chan, 1991 .

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides.

Denis Labrecque, Darius Bilimoria, Lucille L'Heureux, 2004, Bioorganic & medicinal chemistry letters.

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: tertiary amides.

Darius Bilimoria, Lucille L'Heureux, R. Bethell, 2004, Bioorganic & medicinal chemistry letters.

Potent and orally efficacious benzothiazole amides as TRPV1 antagonists.

D. Labrecque, M. Maudet, M. Svensson, 2012, Bioorganic & medicinal chemistry letters.