P. A. Wells

发表

Inhibitors of HCV NS5B polymerase. Part 1: Evaluation of the southern region of (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid.

Jeffrey A Pfefferkorn, B. Finzel, R. Nugent, 2005, Bioorganic & medicinal chemistry letters.

Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design.

D. Knighton, K. Liu, M. Yin, 2010, ACS medicinal chemistry letters.

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

Yan Zhang, Mark R. Emmett, Alan G. Marshall, 2009, Proceedings of the National Academy of Sciences.

Targeting S-adenosylmethionine biosynthesis with a novel allosteric inhibitor of Mat2A.

S. Kaiser, P. A. Wells, A. Stewart, 2017, Nature chemical biology.

Crystal Structure of a Novel Dimeric Form of NS5A Domain I Protein from Hepatitis C Virus (cid:1)

M. Hickey, P. A. Wells, O. Brodsky, 2009 .

Highly Selective and Potent Thiophenes as PI3K Inhibitors with Oral Antitumor Activity.

G. Paderes, N. Sach, K. Liu, 2011, ACS medicinal chemistry letters.

Castor Bean Components, The Chemistry of Allergens. Inactivation of the Castor Bean Allergens and Ricin by Heating with Aqueous Calcium Hydroxide

P. A. Wells, J. Spies, E. J. Coulson, 1962 .

Conformationally-restricted cyclic sulfones as potent and selective mTOR kinase inhibitors.

K. Liu, M. Yin, P. A. Wells, 2012, Bioorganic & medicinal chemistry letters.

Recombinant human cytomegalovirus protease with a C-terminal (His)6 extension: purification, autocatalytic release of the mature enzyme, and biochemical characterization.

B. Finzel, A. Tomasselli, E. Baldwin, 1998, Protein expression and purification.

Broad-Spectrum Antiherpes Activities of 4-Hydroxyquinoline Carboxamides, a Novel Class of Herpesvirus Polymerase Inhibitors

R. Poorman, P. A. Wells, J. Shelly, 2002, Antimicrobial Agents and Chemotherapy.

Crystal Structure of the Herpes Simplex Virus 1 DNA Polymerase*

Eric T Baldwin, Xiayang Qiu, E. Baldwin, 2006, Journal of Biological Chemistry.

Crystal Structure of a Novel Dimeric Form of NS5A Domain I Protein from Hepatitis C Virus

M. Hickey, P. A. Wells, O. Brodsky, 2009, Journal of Virology.

Biochemical characterization of recombinant hepatitis C virus nonstructural protein 4B: evidence for ATP/GTP hydrolysis and adenylate kinase activity.

A. Thompson, Jiangli Yan, P. A. Wells, 2009, Biochemistry.

Inhibitors of HCV NS5B polymerase. Part 2: Evaluation of the northern region of (2Z)-2-benzoylamino-3-(4-phenoxy-phenyl)-acrylic acid.

Richard Nugent, Jeffrey A Pfefferkorn, B. Finzel, 2005, Bioorganic & medicinal chemistry letters.

Crystal Structure of a Novel Dimeric Form of NS5A Domain I Protein from Hepatitis C Virus

M. Hickey, P. A. Wells, O. Brodsky, 2009, Journal of Virology.