F. Bonelli

发表

Potent inhibitors of subgenomic hepatitis C virus RNA replication through optimization of indole-N-acetamide allosteric inhibitors of the viral NS5B polymerase.

Michael Rowley, Frank Narjes, Giovanni Migliaccio, 2005 .

Dihydroxypyrimidine-4-carboxamides as novel potent and selective HIV integrase inhibitors.

D. Hazuda, S. Harper, M. Rowley, 2007, Journal of medicinal chemistry.

Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection.

D. Hazuda, M. Rowley, V. Summa, 2008, Journal of medicinal chemistry.

Inhibition of retinal and choroidal neovascularization by a novel KDR kinase inhibitor.

Kenneth D Anderson, G. Ciliberto, T. Vogt, 2005, Molecular vision.

Enhanced mass resolution method development, validation and assay application to support preclinical studies of a new drug candidate.

Vincenzo Pucci, R. Laufer, F. Bonelli, 2006, Rapid communications in mass spectrometry : RCM.

DPP‐IV‐resistant, long‐acting oxyntomodulin derivatives

A. Pocai, F. Bonelli, A. Pessi, 2011, Journal of peptide science : an official publication of the European Peptide Society.

Quantitative Prediction of Human Clearance Guiding the Development of Raltegravir (MK-0518, Isentress) and Related HIV Integrase Inhibitors

M. Rowley, V. Summa, R. Laufer, 2009, Drug Metabolism and Disposition.

Reactivity of the NS2/3(907-1206)ASK(4) protein with beta-mercaptoethanol studied by electrospray ion trap mass spectrometry.

Laura Orsatti, F. Bonelli, S. Orrù, 2002, Rapid communications in mass spectrometry : RCM.

Moving from fast to ballistic gradient in liquid chromatography/tandem mass spectrometry pharmaceutical bioanalysis: Matrix effect and chromatographic evaluations.

F. Bonelli, C. De Nardi, 2006, Rapid communications in mass spectrometry : RCM.

ApoA-I mimetic peptides promote pre-β HDL formation in vivo causing remodeling of HDL and triglyceride accumulation at higher dose.

F. Bonelli, B. Hubbard, A. Pessi, 2010, Bioorganic & medicinal chemistry.

Determination of the stoichiometry of noncovalent complexes using reverse-phase high-performance liquid chromatography coupled with electrospray ion trap mass spectrometry.

A. Vannini, Laura Orsatti, F. Bonelli, 2002, Analytical biochemistry.

Development of a simple and reliable accurate mass liquid chromatography/electrospray ionization mass spectrometry method for high-resolution accurate mass determinations of new drug entities on a triple quadrupole mass spectrometer.

F. Bonelli, V. Pucci, 2007, Rapid communications in mass spectrometry : RCM.

A single-run liquid chromatography mass spectrometry method to quantify neuroactive kynurenine pathway metabolites in rat plasma.

C. Dominguez, Laura Orsatti, F. Bonelli, 2015, Journal of pharmaceutical and biomedical analysis.

A multiple antigen peptide from the repetitive sequence of the Plasmodium malariae circumsporozoite protein induces a specific antibody response in mice of various H‐2 haplotypes

F. Bonelli, J. Louis, P. Lambert, 1990, European journal of immunology.

HILIC LC-MS for the determination of 2'-C-methyl-cytidine-triphosphate in rat liver.

C. Giuliano, F. Bonelli, K. Koeplinger, 2009, Journal of separation science.

Oligomerization, albumin binding and catabolism of therapeutic peptides in the subcutaneous compartment: An investigation on lipidated GLP-1 analogs.

Laura Orsatti, F. Bonelli, E. Monteagudo, 2022, Journal of pharmaceutical and biomedical analysis.

Optimization of Thienopyrrole‐Based Finger‐Loop Inhibitors of the Hepatitis C Virus NS5B Polymerase

U. Koch, F. Narjes, N. Gennari, 2009, ChemMedChem.

Determination of acetyl coenzyme A in human whole blood by ultra-performance liquid chromatography-mass spectrometry.

D. Elbaum, Laura Orsatti, F. Bonelli, 2018, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Synthetic Plasmodium falciparum circumsporozoite peptides elicit heterogenous L3T4+ T cell proliferative responses in H-2b mice.

F. Bonelli, A. Pessi, G. Del Giudice, 1986, Journal of immunology.

Determination of asymmetric dimethyl arginine in human serum by liquid chromatography-tandem mass spectrometry: clinical application in hypertensive subjects

F. Bonelli, R. Calvani, B. Zappacosta, 2011, Clinical chemistry and laboratory medicine.

Discovery and synthesis of HIV integrase inhibitors: development of potent and orally bioavailable N-methyl pyrimidones.

Michael Rowley, Cristina Gardelli, Marco Ferrara, 2007, Journal of medicinal chemistry.

Structural characterization of a new class of penem beta-lactam antibiotics by triple quadrupole tandem mass spectrometry.

F. Bonelli, A. Triolo, 1995, Rapid communications in mass spectrometry : RCM.

Addition of a cholesterol group to an HIV-1 peptide fusion inhibitor dramatically increases its antiviral potency

John P. Moore, T. Ketas, F. Bonelli, 2009, Proceedings of the National Academy of Sciences.

A novel strategy for reducing phospholipids-based matrix effect in LC-ESI-MS bioanalysis by means of HybridSPE.

Vincenzo Pucci, Serena Di Palma, F. Bonelli, 2009, Journal of pharmaceutical and biomedical analysis.

Turbulent flow chromatography TFC-tandem mass spectrometry supporting in vitro/vivo studies of NCEs in high throughput fashion.

F. Bonelli, A. Di Marco, E. Monteagudo, 2010, Journal of pharmaceutical and biomedical analysis.

Identification of human urinary metabolites of isbufylline by high-performance liquid chromatography/thermospray mass spectrometry.

F. Bonelli, A. Triolo, O. Agostini, 1994, Biological mass spectrometry.

Potent inhibitors of subgenomic hepatitis C virus RNA replication through optimization of indole-N-acetamide allosteric inhibitors of the viral NS5B polymerase.

Michael Rowley, Frank Narjes, Giovanni Migliaccio, 2005, Journal of medicinal chemistry.

High sensitivity determination of valproic acid in mouse plasma using semi-automated sample preparation and liquid chromatography with tandem mass spectrometric detection.

F. Bonelli, E. Monteagudo, V. Pucci, 2005, Rapid communications in mass spectrometry : RCM.

Multiple antigen peptides (MAPs) as candidate vaccines against malaria.

F. Bonelli, P. Lambert, E. Bianchi, 1991, Parassitologia.

Immunogenicity of a non-repetitive sequence of Plasmodium falciparum circumsporozoite protein in man and mice.

F. Bonelli, A. Pessi, C. Chizzolini, 1988, Immunology.

Characterization of the Hepatitis C Virus NS2/3 Processing Reaction by Using a Purified Precursor Protein

C. Nardella, F. Narjes, Laura Orsatti, 2001, Journal of Virology.

Use of 'dilute-and-shoot' liquid chromatography-high resolution mass spectrometry in preclinical research: application to a DMPK study of perhexiline in mouse plasma.

Laura Orsatti, F. Bonelli, E. Monteagudo, 2016, Journal of pharmaceutical and biomedical analysis.

An efficient liquid chromatography-high resolution mass spectrometry approach for the optimization of the metabolic stability of therapeutic peptides

Laura Orsatti, F. Bonelli, E. Bianchi, 2017, Analytical and Bioanalytical Chemistry.

Synthesis and biological evaluation of novel NK‐1 tachykinin receptor antagonists: The use of cycloalkyl amino acids as a template

A. Sisto, C. Maggi, C. Goso, 1995, Biopolymers.

Solid phase synthesis of retro-inverso peptide analogues. Synthesis and biological activity of the partially modified retro-inverso analogue of the bradykinin potentiating peptide BPP9a [gLys6, (RS)-mPhe7, Ala8] BPP9a.

F. Bonelli, A. Pessi, A. Verdini, 2009, International journal of peptide & protein research.

Application of the continuous-flow polyamide method to the solid-phase synthesis of a multiple antigen peptide (MAP) based on the sequence of a malaria epitope

F. Bonelli, A. Pessi, E. Bianchi, 1990 .

Turnover rate of coenzyme A in mouse brain and liver

D. Elbaum, Laura Orsatti, F. Bonelli, 2021, PloS one.

Development of 2-t butyl-N-methyl pyrimidones as potent inhibitors of HIV integrase.

M. Rowley, V. Summa, P. Pace, 2008, Bioorganic & Medicinal Chemistry Letters.

Identification of the metabolites of MX/2/120 in the guinea-pig by high-performance liquid chromatography/thermospray tandem mass spectrometry

F. Bonelli, A. Triolo, E. Toja, 1995 .

A novel, inducible, eukaryotic gene expression system based on the quorum‐sensing transcription factor TraR

R. Cortese, C. Gargioli, R. De Francesco, 2003 .