T. Graybill

发表

An efficient, asymmetric solid-phase synthesis of benzothiadiazine-substituted tetramic acids: potent inhibitors of the hepatitis C virus RNA-dependent RNA polymerase.

G. Burton, R. Sarisky, Victor K. Johnston, 2006, Bioorganic & medicinal chemistry letters.

Cell-Based Selection Expands the Utility of DNA-Encoded Small-Molecule Library Technology to Cell Surface Drug Targets: Identification of Novel Antagonists of the NK3 Tachykinin Receptor.

Jean Zhang, T. Graybill, D. Israel, 2015, ACS combinatorial science.

Amino acid anthranilamide derivatives as a new class of glycogen phosphorylase inhibitors.

Mehul M. Patel, S. Thrall, D. Tew, 2008, Bioorganic & medicinal chemistry letters.

Examination of Tetrahydro- and Dihydrobisfuran Formation in Aflatoxin Biosynthesis: From Whole Cells to Purified Enzymes

C. Townsend, T. Graybill, S. McGuire, 1992 .

Synthesis and evaluation of diacylhydrazines as inhibitors of the interleukin-1β converting enzyme (ICE)

T. Graybill, R. Dolle, M. Ator, 1995 .

Structural and stereochemical requirements of time-dependent inactivators of the interleukin-1β converting enzyme

Robert E. Miller, T. Graybill, C. Prouty, 1995 .

Pyridazinodiazepines as a high-affinity, P2-P3 peptidomimetic class of interleukin-1 beta-converting enzyme inhibitor.

D. Hoyer, T. Graybill, C. Prouty, 1997, Journal of medicinal chemistry.

α-((Tetronoyl)oxy)- and α-((tetramoyl)oxy)methyl ketone inhibitors of the interleukin-1β converting enzyme (ICE)

T. Graybill, C. Prouty, R. Dolle, 1997 .

Preparation and evaluation of peptidic aspartyl hemiacetals as reversible inhibitors of interleukin-1 beta converting enzyme (ICE).

T. Graybill, R. Dolle, M. Ator, 2009, International journal of peptide and protein research.

Design of amidobenzimidazole STING receptor agonists with systemic activity

Joseph P. Romano, J. Bertin, J. Adams, 2018, Nature.

Aspartyl alpha-((diphenylphosphinyl)oxy)methyl ketones as novel inhibitors of interleukin-1 beta converting enzyme. Utility of the diphenylphosphinic acid leaving group for the inhibition of cysteine proteases.

T. Graybill, R. Dolle, D. Whipple, 1995, Journal of medicinal chemistry.

Aspartyl alpha-((1-phenyl-3-(trifluoromethyl)-pyrazol-5-yl)oxy)methyl ketones as interleukin-1 beta converting enzyme inhibitors. Significance of the P1 and P3 amido nitrogens for enzyme-peptide inhibitor binding.

D. Hoyer, T. Graybill, J. Salvino, 1994, Journal of medicinal chemistry.

Synthesis and structure-activity relationships of 3-phenyl-2-propenamides as inhibitors of glycogen phosphorylase a.

Mehul M. Patel, K. Evans, T. Graybill, 2006, Bioorganic & medicinal chemistry letters.

Tetrahydro-4-quinolinamines identified as novel P2Y(1) receptor antagonists.

Dwight M. Morrow, N. Aiyar, P. Li, 2008, Bioorganic & medicinal chemistry letters.

2-Amino-9-aryl-3-cyano-4-methyl-7-oxo-6,7,8,9-tetrahydropyrido[2',3':4,5]thieno[2,3-b]pyridine derivatives as selective progesterone receptor agonists.

C. Duraiswami, Yonghui Wang, T. Graybill, 2009, Bioorganic & medicinal chemistry letters.

Efficient one-pot preparation of 5-substituted-2-amino-1,3,4-oxadiazoles using resin-bound reagents

G. Burton, K. Evans, T. Graybill, 2004 .

Silyl Triflate-Mediated Ring-Closure and Rearrangement in the Synthesis of Potential Bisfuran-Containing Intermediates of Aflatoxin Biosynthesis

C. Townsend, T. Graybill, K. Pal, 1999 .

Efficient One-Pot Preparation of 5-Substituted-2-amino-1,3,4-oxadiazoles Using Resin-Bound Reagents.

G. Burton, K. Evans, T. Graybill, 2004 .

A convenient ‘catch and release’ synthesis of fused 2-alkylthio-pyrimidinones mediated by polymer-bound BEMP

G. Burton, T. Graybill, R. Rivero, 2003 .

Synthesis and evaluation of azapeptide-derived inhibitors of serine and cysteine proteases☆

M. Ross, T. Graybill, R. Dolle, 1992 .

Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening

Gang Yao, Bing Xia, Jing Chai, 2017, Nature Communications.

Design of amidobenzimidazole STING receptor agonists with systemic activity

J. Bertin, J. Adams, M. Bantscheff, 2018, Nature.

Monoacylation of unprotected symmetrical diamines with resin-bound benzoic acids

Yonghui Wang, T. Graybill, R. Rivero, 2004 .

Parallel Hit Progression Strategy Identifies Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit Plasmodium falciparum Parasite Proliferation.

Deepak Bandyopadhyay, M. Akabas, T. Graybill, 2019, ACS infectious diseases.

Inhibition of Human Erythrocyte Calpain I by Novel Quinolinecarboxamides.

T. Graybill, R. Dolle, Matthew S. Miller, 1995 .

Characterization of a continuous fluorogenic assay for calpain I. Kinetic evaluation of peptide aldehydes, halomethyl ketones and (acyloxy)methyl ketones as inhibitors of the enzyme

T. Graybill, R. Dolle, A. Maycock, 1995 .

Author Correction: Design of amidobenzimidazole STING receptor agonists with systemic activity

Joseph P. Romano, J. Bertin, M. Bantscheff, 2019, Nature.

Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3.

Siva Lavu, Lei Jin, T. Graybill, 2013, Journal of medicinal chemistry.

The timing of aromatic deoxygenation in aflatoxin biosynthesis

C. Townsend, T. Graybill, S. McGuire, 1989 .

Camphor sulfonamide derivatives as novel, potent and selective CXCR3 antagonists.

Todd L Graybill, H. Sarau, J. Foley, 2009, Bioorganic & medicinal chemistry letters.

Encoded Library Technology Screening of Hepatitis C Virus NS4B Yields a Small-Molecule Compound Series with In Vitro Replicon Activity

Zhengrong Zhu, T. Graybill, M. Thomson, 2015, Antimicrobial Agents and Chemotherapy.

Partitioning of tetrahydro- and dihydrobisfuran formation in aflatoxin biosynthesis defined by cell-free and direct incorporation experiments

C. Townsend, T. Graybill, S. McGuire, 1989 .

Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening

Robert H Bates, G. Besra, J. Lelièvre, 2017, Nature Communications.

Inhibition of human erythrocyte calpain I by novel quinolinecarboxamides

T. Graybill, Matthew S. Miller, J. SchmidtStanley, 1995 .

Parallel Hit Progression Strategy Identifies Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit Plasmodium falciparum Parasite Proliferation

M. Akabas, T. Graybill, K. Widdowson, 2020 .