G. Ciszewski

发表

Discovery of proline sulfonamides as potent and selective hepatitis C virus NS5b polymerase inhibitors. Evidence for a new NS5b polymerase binding site.

Rajiv Chopra, Atul Agarwal, Boris Feld, 2006, Journal of medicinal chemistry.

Identification of Pyrazolo[1,5-a]pyrimidine-3-carboxylates as B-Raf Kinase Inhibitors.

D. Wojciechowicz, Steven C. Kim, L. Feldberg, 2009 .

Identification of pyrazolo[1,5-a]pyrimidine-3-carboxylates as B-Raf kinase inhibitors.

D. Wojciechowicz, Steven C. Kim, L. Feldberg, 2009, Bioorganic & medicinal chemistry letters.

Design and synthesis of 3,4-dihydro-1H-[1]-benzothieno[2,3-c]pyran and 3,4-dihydro-1H-pyrano[3,4-b]benzofuran derivatives as non-nucleoside inhibitors of HCV NS5B RNA dependent RNA polymerase.

A. Gopalsamy, G. Ciszewski, J. Ellingboe, 2006, Bioorganic & medicinal chemistry letters.

Synthesis of pyrazolo[1,5 -α ]pyrimidinone regioisomers

J. McKew, G. Ciszewski, D. Cole, 2007 .

Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors.

D. Berger, M. Dutia, D. Powell, 2009, Bioorganic & medicinal chemistry letters.

Hit to lead optimization of pyrazolo[1,5-a]pyrimidines as B-Raf kinase inhibitors.

D. Berger, D. Wojciechowicz, Steven C. Kim, 2009, Bioorganic & medicinal chemistry letters.

Hit to lead optimization of pyrazolo[1,5-a]pyrimidines as B-Raf kinase inhibitors.

D. Berger, D. Wojciechowicz, Steven C. Kim, 2009, Bioorganic & medicinal chemistry letters.

Design and synthesis of 2,3,4,9-tetrahydro-1H-carbazole and 1,2,3,4-tetrahydro-cyclopenta[b]indole derivatives as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymerase.

A. Gopalsamy, G. Ciszewski, M. Shi, 2006, Bioorganic & medicinal chemistry letters.

Identification of a new class of small molecule C5a receptor antagonists.

G. Ciszewski, J. Ellingboe, G. Tawa, 2010, Bioorganic & medicinal chemistry letters.

Inhibition of Tpl2 kinase and TNF-alpha production with 1,7-naphthyridine-3-carbonitriles: synthesis and structure-activity relationships.

J. Telliez, A. Gopalsamy, G. Ciszewski, 2005, Bioorganic & medicinal chemistry letters.

Potent and selective carboxylic acid-based inhibitors of matrix metalloproteinases.

G. Ciszewski, M. Natchus, N. Almstead, 2001, Journal of medicinal chemistry.

Discovery of pyrano[3,4-b]indoles as potent and selective HCV NS5B polymerase inhibitors.

Boris Feld, A. Gopalsamy, Kitae Lim, 2004, Journal of medicinal chemistry.

Late Stage Lead Diversification (LSLD) Coupled with Quantitative NMR Spectroscopy to Identify New SAR Vectors at Nanomole Scale Synthesis: Application to Loratadine a Human Histamine H1 Receptor Inverse Agonist.

G. S. Walker, R. Obach, N. Sach, 2020, Journal of medicinal chemistry.

MICHAELIS-BECKER SYNTHESIS OF bis(2,2,2-TRIFLUOROETHYL)PHOSPHONO ESTERS

G. Ciszewski, J. A. Jackson, 1999 .