J. O'Connell

发表

Discovery of proline sulfonamides as potent and selective hepatitis C virus NS5b polymerase inhibitors. Evidence for a new NS5b polymerase binding site.

Rajiv Chopra, Atul Agarwal, Boris Feld, 2006, Journal of medicinal chemistry.

Use of Ribotyping To Retrospectively Identify Methicillin-Resistant Staphylococcus aureus Isolates from Phase 3 Clinical Trials for Tigecycline That Are Genotypically Related to Community-Associated Isolates

J. O'Connell, P. Bradford, B. Kreiswirth, 2005, Antimicrobial Agents and Chemotherapy.

Elongation of Synthetic RNA Templates by Hepatitis C Virus NS5B Polymerase*

R. Chopra, J. O'Connell, Cuihua Liu, 2004, Journal of Biological Chemistry.

Treatment of human enterovirus infections.

J. O'Connell, H. Rotbart, M. Mckinlay, 1998, Antiviral research.

Molecular Mechanism of Hepatitis C Virus Replicon Variants with Reduced Susceptibility to a Benzofuran Inhibitor, HCV-796

R. Chopra, J. Bard, G. Krishnamurthy, 2008, Antimicrobial Agents and Chemotherapy.

Identification of Small Molecule Compounds That Selectively Inhibit Varicella-Zoster Virus Replication

J. Cohen, K. Curran, B. Feld, 2003, Journal of Virology.

Functional, Biophysical, and Structural Bases for Antibacterial Activity of Tigecycline

T. Rush, J. O'Connell, E. Feyfant, 2006, Antimicrobial Agents and Chemotherapy.

Tigecycline MIC Testing by Broth Dilution Requires Use of Fresh Medium or Addition of the Biocatalytic Oxygen-Reducing Reagent Oxyrase To Standardize the Test Method

J. O'Connell, P. Bradford, M. Young, 2005, Antimicrobial Agents and Chemotherapy.

Specific Inhibition of Human Cytomegalovirus Glycoprotein B-Mediated Fusion by a Novel Thiourea Small Molecule

B. Feld, J. O'Connell, J. Bloom, 2004, Journal of Virology.

Novel Nonnucleoside Inhibitor of Hepatitis C Virus RNA-Dependent RNA Polymerase

A. Gopalsamy, J. Ellingboe, A. Howe, 2004, Antimicrobial Agents and Chemotherapy.

C Virus RNA-Dependent RNA Polymerase Novel Nonnucleoside Inhibitor of Hepatitis

A. Gopalsamy, J. Ellingboe, A. Howe, 2004 .

Inhalation efficacy of RFI‐641 in an African green monkey model of RSV infection

M. E. Lynch, J. O'Connell, C. Huntley, 2003, Journal of medical primatology.

RFI-641, a Potent Respiratory Syncytial Virus Inhibitor

A. Gazumyan, B. Feld, J. O'Connell, 2002, Antimicrobial Agents and Chemotherapy.

Discovery of pyrano[3,4-b]indoles as potent and selective HCV NS5B polymerase inhibitors.

Boris Feld, A. Gopalsamy, Kitae Lim, 2004, Journal of medicinal chemistry.

SCH 43478 and analogs: in vitro activity and in vivo efficacy of novel agents for herpesvirus type 2.

A. Kwong, J. O'Connell, E. Rozhon, 1997, Antiviral Research.

In Vitro and In Vivo Activities of Novel 6-Methylidene Penems as β-Lactamase Inhibitors

J. O'Connell, T. Mansour, P. Bradford, 2004, Antimicrobial Agents and Chemotherapy.

HCV796: A selective nonstructural protein 5B polymerase inhibitor with potent anti‐hepatitis C virus activity In Vitro, in mice with chimeric human livers, and in humans infected with hepatitis C virus

D. Douglas, Jamie T. Lewis, G. Lund, 2009, Hepatology.

Molecular Mechanism of a Thumb Domain Hepatitis C Virus Nonnucleoside RNA-Dependent RNA Polymerase Inhibitor

R. Chopra, A. Agarwal, A. Howe, 2006, Antimicrobial Agents and Chemotherapy.

Anti‐HCV therapies in chimeric scid‐Alb/uPA mice parallel outcomes in human clinical application

Z. Ni, D. Tyrrell, A. Weiner, 2006, Hepatology.

Diagnosis of enterovirus infection by polymerase chain reaction of multiple specimen types.

J. O'Connell, G. Mccracken, R. Dagan, 1997, The Pediatric infectious disease journal.

SCH 38057: a picornavirus capsid-binding molecule with antiviral activity after the initial stage of viral uncoating.

E. Arnold, J. O'Connell, G. Miller, 1993, Antiviral research.

Antipicornavirus activity of SCH 47802 and analogs: in vitro and in vivo studies.

J. O'Connell, E. Rozhon, A. Skelton, 1996, Antiviral research.

Development of Antiviral Agents for Picornavirus Infections

J. O'Connell, J. Schwartz, P. Grint, 1995 .

Small molecule inhibitors of HIV RT Ribonuclease H.

G. Krishnamurthy, J. O'Connell, Yongbo Hu, 2010, Bioorganic & medicinal chemistry letters.

The Discovery of Pyrano[3,4‐b]indole‐Based Allosteric Inhibitors of HCV NS5B Polymerase with In Vivo Activity

N. Kneteman, A. Howe, J. O'Connell, 2008, ChemMedChem.

Influence of viral transport media and freeze-thaw cycling on the sensitivity of qRT-PCR detection of SARS-CoV-2 nucleic acids

Gil U. Lee, J. O'Connell, M. Carr, 2021, bioRxiv.

Structure of poliovirus type 2 Lansing complexed with antiviral agent SCH48973: comparison of the structural and biological properties of three poliovirus serotypes.

E. Arnold, J. O'Connell, E. Rozhon, 1997, Structure.

SCH 48973: a potent, broad-spectrum, antienterovirus compound

J. O'Connell, J. Modlin, E. Rozhon, 1997, Antimicrobial agents and chemotherapy.

Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymerase.

Rajiv Chopra, Atul Agarwal, Kevin Curran, 2007, Journal of medicinal chemistry.