Jianru Wang

发表

Hypoxia suppresses serum deprivation‐induced degradation of the nucleus pulposus cell extracellular matrix through the JNK and NF‐κB pathways

Jianru Wang, H. Pan, Xiang Li, 2017, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Resistin Promotes Intervertebral Disc Degeneration by Upregulation of ADAMTS-5 Through p38 MAPK Signaling Pathway

Jianru Wang, Xiang Li, Caijun Liu, 2016, Spine.

LIM mineralization protein‐1 suppresses TNF‐α induced intervertebral disc degeneration by maintaining nucleus pulposus extracellular matrix production and inhibiting matrix metalloproteinases expression

Jianru Wang, H. Pan, Xiang Li, 2015, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

TGF-β1 antagonizes TNF-α induced up-regulation of matrix metalloproteinase 3 in nucleus pulposus cells: role of the ERK1/2 pathway

Fei Gao, Zhaomin Zheng, F. Gao, 2015, Connective tissue research.

Paraoxonase 1 (PON1) was Negatively Associated with Intervertebral Disc Degeneration (IVDD).

Jianru Wang, Ze-min Li, Hua Wang, 2019, Spine.

Inflammation Intensity–Dependent Expression of Osteoinductive Wnt Proteins Is Critical for Ectopic New Bone Formation in Ankylosing Spondylitis

Jianru Wang, H. Pan, Xiang Li, 2018, Arthritis & rheumatology.

Posterior vertebral column resection in spinal deformity: a systematic review

Samuel K. Cho, Jianru Wang, Zhaomin Zheng, 2016, European Spine Journal.

Both expression of cytokines and posterior annulus fibrosus rupture are essential for pain behavior changes induced by degenerative intervertebral disc: An experimental study in rats

Jianru Wang, Kuibo Zhang, Ze-min Li, 2014, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Growth differentiation factor‐6 attenuates inflammatory and pain‐related factors and degenerated disc‐induced pain behaviors in rat model

Jianru Wang, Ze-min Li, Hua Wang, 2020, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

TNF‐α enhances apoptosis by promoting chop expression in nucleus pulposus cells: role of the MAPK and NF‐κB pathways

Jianru Wang, Ze-min Li, Hua Wang, 2019, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Comparison of the use of rhBMP-7 versus iliac crest autograft in single-level lumbar fusion: a meta-analysis of randomized controlled trials

Jianru Wang, Hua Wang, Zhaomin Zheng, 2017, Journal of Bone and Mineral Metabolism.

Comparison study of clinical outcomes and sagittal alignment improvement between anterior and posterior fusion techniques for multilevel cervical spondylotic myelopathy

Jianru Wang, Xiang Li, Ze-min Li, 2021, Journal of orthopaedic surgery.

Genomic G-quadruplex folding triggers a cytokine-mediated inflammatory feedback loop to aggravate inflammatory diseases

Jianru Wang, Xiaolin Wang, Fan Chen, 2022, iScience.

Correlation study of radiographic characteristics and operative difficulty in lateral–anterior lumbar interbody fusion (LaLIF) at the L4-5 level: a novel classification for case selection

Jianru Wang, Ze-min Li, Hua Wang, 2020, European Spine Journal.

Perioperative Complications in 255 Patients Who Underwent Lateral Anterior Lumbar Interbody Fusion (LaLIF) Surgery

Jianru Wang, Ze-min Li, Hua Wang, 2021, European Spine Journal.

Lateral-anterior lumbar interbody fusion (LaLIF) for lumbar degenerative disease: Technical notes, surgical system, and mid-term outcomes

Jianru Wang, Ze-min Li, Hua Wang, 2021, Journal of orthopaedic translation.

Grem1 accelerates nucleus pulposus cell apoptosis and intervertebral disc degeneration by inhibiting TGF-β-mediated Smad2/3 phosphorylation

Jianru Wang, Ze-min Li, Hua Wang, 2022, Experimental & molecular medicine.

LIM Mineralization Protein‐1 Enhances Bone Morphogenetic Protein‐2–Mediated Osteogenesis Through Activation of ERK1/2 MAPK Pathway and Upregulation of Runx2 Transactivity

Jianru Wang, H. Pan, Xiang Li, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-κB.

I. Shapiro, M. Risbud, N. Fujita, 2013, The American journal of pathology.

Circular RNA circ-4099 is induced by TNF-α and regulates ECM synthesis by blocking miR-616-5p inhibition of Sox9 in intervertebral disc degeneration

Zhaomin Zheng, Jianru Wang, H. Pan, 2018, Experimental & Molecular Medicine.

TNF-α and IL-1β Promote a Disintegrin-like and Metalloprotease with Thrombospondin Type I Motif-5-mediated Aggrecan Degradation through Syndecan-4 in Intervertebral Disc*

I. Shapiro, M. Risbud, D. Markova, 2011, The Journal of Biological Chemistry.

Experience of Intraoperative Cell Salvage in Surgical Correction of Spinal Deformity

Jianru Wang, Ze-min Li, Hua Wang, 2016, Medicine.

Main thoracic curve adolescent idiopathic scoliosis: association of higher rod stiffness and concave-side pedicle screw density with improvement in sagittal thoracic kyphosis restoration.

Jianru Wang, Xiang Li, Kuibo Zhang, 2015, Journal of neurosurgery. Spine.

Melatonin alleviates intervertebral disc degeneration by disrupting the IL-1β/NF-κB-NLRP3 inflammasome positive feedback loop

Jianru Wang, H. Pan, Ze-min Li, 2020, Bone Research.

Melatonin activates autophagy via the NF-κB signaling pathway to prevent extracellular matrix degeneration in intervertebral disc.

Jianru Wang, Ze-min Li, Zhaomin Zheng, 2020, Osteoarthritis and cartilage.

Aberrant upregulation of CaSR promotes pathological new bone formation in ankylosing spondylitis

Jianru Wang, Xiang Li, Kuibo Zhang, 2020, EMBO molecular medicine.

Tenascin-C-mediated suppression of extracellular matrix adhesion force promotes entheseal new bone formation through activation of Hippo signalling in ankylosing spondylitis

Jianru Wang, Xiang Li, Ze-min Li, 2021, Annals of the Rheumatic Diseases.

Piezo1-mediated mechanotransduction promotes entheseal pathological new bone formation in ankylosing spondylitis

Jianru Wang, Xiang Li, Ze-min Li, 2022, Annals of the rheumatic diseases.

Wnt4 signaling mediates protective effects of melatonin on new bone formation in an inflammatory environment

Jianru Wang, Xiang Li, Ze-min Li, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

JAG2/Notch2 inhibits intervertebral disc degeneration by modulating cell proliferation, apoptosis, and extracellular matrix

Jianru Wang, H. Pan, Ze-min Li, 2019, Arthritis Research & Therapy.

Comparison of Smith-Petersen Osteotomy and Pedicle Subtraction Osteotomy for the Correction of Thoracolumbar Kyphotic Deformity in Ankylosing Spondylitis: A Systematic Review and Meta-analysis

Jianru Wang, Hua Wang, Zhaomin Zheng, 2015, Spine.

Halo-gravity traction in the treatment of severe spinal deformity: a systematic review and meta-analysis

Samuel K. Cho, Jianru Wang, Zhaomin Zheng, 2017, European Spine Journal.

Matching correction of main and compensatory curves is critical for immediate postoperative coronal balance in correction of severe adult idiopathic scoliosis

Jianru Wang, Ze-min Li, Hua Wang, 2021, European Spine Journal.

Biomechanical Effect of 4-Rod Technique on Lumbosacral Fixation: An In Vitro Human Cadaveric Investigation

Jianru Wang, Ze-min Li, Zhaomin Zheng, 2013, Spine.

CXCL12/CXCR4-Rac1–mediated migration of osteogenic precursor cells contributes to pathological new bone formation in ankylosing spondylitis

Jianru Wang, Xiang Li, Kuibo Zhang, 2022, Science advances.

Comparison of Percutaneous Vertebroplasty and Balloon Kyphoplasty for the Treatment of Single Level Vertebral Compression Fractures: A Meta-analysis of the Literature.

Jianru Wang, Hua Wang, Zhaomin Zheng, 2015, Pain physician.

Risk Factors Associated with Pain Severity in Patients with Non-specific Low Back Pain in Southern China

Jianru Wang, Ze-min Li, Hua Wang, 2018, Asian spine journal.

Low back pain associated with lumbar disc herniation: role of moderately degenerative disc and annulus fibrous tears.

Jianru Wang, Kuibo Zhang, Ze-min Li, 2015, International journal of clinical and experimental medicine.

Comparison of unilateral versus bilateral pedicle screw fixation in lumbar interbody fusion: a meta-analysis

Jianru Wang, Zhaomin Zheng, Hui Liu, 2014, European Spine Journal.

Comparison of pullout strength of the thoracic pedicle screw between intrapedicular and extrapedicular technique: a meta-analysis and literature review.

Jianru Wang, Ze-min Li, Hua Wang, 2015, International journal of clinical and experimental medicine.

Role of the miR-133a-5p/FBXO6 axis in the regulation of intervertebral disc degeneration

Jianru Wang, H. Pan, Ze-min Li, 2021, Journal of orthopaedic translation.

TGF-β1 suppresses CCL3/4 expression through the ERK signaling pathway and inhibits intervertebral disc degeneration and inflammation-related pain in a rat model

Hui Liu, Jianru Wang, Xiang Li, 2017, Experimental &Molecular Medicine.

Inflammatory Cytokines Induce NOTCH Signaling in Nucleus Pulposus Cells

I. Shapiro, M. Risbud, C. L. Le Maitre, 2013, The Journal of Biological Chemistry.

Tumor necrosis factor α- and interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1.

Gail Haddock, Irving M Shapiro, Makarand V Risbud, 2013, Arthritis and rheumatism.

Grem1 accelerates nucleus pulposus cell apoptosis and intervertebral disc degeneration by inhibiting TGF-β-mediated Smad2/3 phosphorylation

Jianru Wang, Hua Wang, Zhaomin Zheng, 2022, Experimental & Molecular Medicine.

Circular RNA hsa_circ_0083756 promotes intervertebral disc degeneration by sponging miR‐558 and regulating TREM1 expression

Jianru Wang, Hua Wang, Zhaomin Zheng, 2022, Cell proliferation.

Clinical atlas of rectal cancer highlights the barriers and insufficient interventions underlying the unfavorable outcomes in older patients

Jianru Wang, Meijin Huang, Zhuoyang Zhao, 2023, Heliyon.

Circular RNA circ-4099 is induced by TNF-α and regulates ECM synthesis by blocking miR-616-5p inhibition of Sox9 in intervertebral disc degeneration

Jianru Wang, H. Pan, Hua Wang, 2018, Experimental & Molecular Medicine.

Five Novel Oncogenic Signatures Could Be Utilized as AFP-Related Diagnostic Biomarkers for Hepatocellular Carcinoma Based on Next-Generation Sequencing

Jianru Wang, Fan Chen, Xiaohui Huang, 2018, Digestive Diseases and Sciences.

Visfatin promotes intervertebral disc degeneration by inducing IL-6 expression through the ERK/JNK/p38 signalling pathways

Jianru Wang, Zhaomin Zheng, Hui Liu, 2021, Adipocyte.

Alarmins S100A8/A9 promote intervertebral disc degeneration and inflammation-related pain in a rat model through toll-like receptor-4 and activation of the NF-κB signaling pathway.

Jiahua Xie, Jianru Wang, Hua Wang, 2022, Osteoarthritis and cartilage.

Association between immediate postoperative hypoalbuminemia and surgical site infection after posterior lumbar fusion surgery

Jiahua Xie, Jianru Wang, Hua Wang, 2023, European Spine Journal.

Smad3 controls β-1,3-glucuronosyltransferase 1 expression in rat nucleus pulposus cells: implications of dysregulated expression in disc disease.

I. Shapiro, M. Risbud, C. Kepler, 2012, Arthritis and rheumatism.

Tumor necrosis factor α- and interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1.

I. Shapiro, M. Risbud, C. L. Le Maitre, 2013, Arthritis and rheumatism.

Resistin promotes CCL4 expression through toll-like receptor-4 and activation of the p38-MAPK and NF-κB signaling pathways: implications for intervertebral disc degeneration.

X. Wang, Jianru Wang, H. Pan, 2017, Osteoarthritis and cartilage.

Five Novel Oncogenic Signatures Could Be Utilized as AFP-Related Diagnostic Biomarkers for Hepatocellular Carcinoma Based on Next-Generation Sequencing

Jianru Wang, Fan Chen, Xiaohui Huang, 2018, Digestive Diseases and Sciences.

TNF-α and TGF-β1 regulate Syndecan-4 expression in nucleus pulposus cells: role of the mitogen-activated protein kinase and NF-κB pathways

Jianru Wang, H. Pan, Xiang Li, 2015, Connective tissue research.

Intermittent administration of PTH for the treatment of inflammatory bone loss does not enhance entheseal pathological new bone formation.

Jianru Wang, Zihao Li, Siwen Chen, 2024, Biochemical and biophysical research communications.

Interplay among pain intensity, sleep disturbance and emotion in patients with non-specific low back pain

Jianru Wang, S. Sribastav, He Peiheng, 2017, PeerJ.

Pain behavior and phenotype in a modified anterior lumbar disc puncture mouse model

Jianru Wang, Hua Wang, Linchuan Lei, 2023, JOR spine.

Wnt5a suppresses inflammation-driven intervertebral disc degeneration via a TNF-α/NF-κB-Wnt5a negative-feedback loop.

Jianru Wang, H. Pan, Xiang Li, 2018, Osteoarthritis and cartilage.