C. Cunningham

J. Rawlins, C. Brayne, D. Bannerman, 2015, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Risk factors for postoperative delirium.

P. Pandharipande, C. Cunningham, R. Sanders, 2014, The lancet. Psychiatry.

Animal Models and Cognitive Testing of Perioperative Neurocognitive Disorders

M. Eckenhoff, C. Cunningham, 2019, The Perioperative Neurocognitive Disorders.

Microglia states and nomenclature: A field at its crossroads

Tuan Leng Tay, Ukpong B. Eyo, I. Amit, 2022, Neuron.

Neuroinflammation in delirium: a postmortem case-control study.

A. Zwinderman, E. Aronica, P. Eikelenboom, 2011, Rejuvenation research.

Environmental influences on antibody-enhanced dengue disease outcomes.

V. Perry, C. Cunningham, G. F. Gomes, 2012, Memorias do Instituto Oswaldo Cruz.

Peripheral infection evokes exaggerated sickness behaviour in pre-clinical murine prion disease

V. Perry, C. Cunningham, M. Combrinck, 2002, Neuroscience.

Correction: A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1β, TNF-α and IL-6 Challenges in C57BL/6 Mice

C. Cunningham, M. Dansereau, D. Skelly, 2013, PLoS ONE.

Astrocytes Are Primed by Chronic Neurodegeneration to Produce Exaggerated Chemokine and Cell Infiltration Responses to Acute Stimulation with the Cytokines IL-1β and TNF-α

C. Cunningham, É. Griffin, E. Griffin, 2015, The Journal of Neuroscience.

Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research

C. Cunningham, E. Hennessy, 2015, Alzheimer's Research & Therapy.

CEREBROSPINAL FLUID INTERLEUKIN‐8 LEVELS ARE HIGHER IN PEOPLE WITH HIP FRACTURE WITH PERIOPERATIVE DELIRIUM THAN IN CONTROLS

S. D. Middleton, B. V. van Munster, S. D. de Rooij, 2011, Journal of the American Geriatrics Society.

DNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative disease

A. Bowie, C. Cunningham, A. Dunne, 2015, Glia.

Systemic Inflammation Induces Acute Behavioral and Cognitive Changes and Accelerates Neurodegenerative Disease

V. Perry, J. Rawlins, K. Lunnon, 2009, Biological Psychiatry.

Reactive astrocyte nomenclature, definitions, and future directions

Kira E. Poskanzer, B. Khakh, C. Rose, 2021, Nature Neuroscience.

Defining Microglial States and Nomenclature: A Roadmap to 2030

Tuan Leng Tay, I. Amit, F. Ginhoux, 2022, SSRN Electronic Journal.

A constant companion

C. Cunningham, 2014 .

Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNα/β and IL-1β responses in the diseased brain and exacerbates chronic neurodegeneration

C. Cunningham, S. Campion, C. Murray, 2010, Brain, Behavior, and Immunity.

The sickness behaviour and CNS inflammatory mediator profile induced by systemic challenge of mice with synthetic double-stranded RNA (poly I:C)

Colm Cunningham, V. Perry, C. Cunningham, 2007, Brain, Behavior, and Immunity.

Systemic infection, interleukin 1β, and cognitive decline in Alzheimer’s disease

V. Perry, C. Holmes, C. Cunningham, 2003, Journal of neurology, neurosurgery, and psychiatry.

MCP-1 and murine prion disease: Separation of early behavioural dysfunction from overt clinical disease

V. Perry, C. Cunningham, D. Boche, 2005, Neurobiology of Disease.

Proinflammatory cytokines, sickness behavior, and Alzheimer disease

V. Perry, C. Holmes, C. Cunningham, 2011, Neurology.

Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research

C. Cunningham, E. Hennessy, 2015, Alzheimer's Research & Therapy.

Priming Microglia for Innate Immune Memory in the Brain.

C. Cunningham, J. Neher, 2019, Trends in immunology.

Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL‐1β drives amplified responses in primed astrocytes and neuronal network dysfunction

M. Cunningham, C. Cunningham, D. Boche, 2021, Alzheimer's & dementia : the journal of the Alzheimer's Association.

Astrocytes: Heterogeneous and Dynamic Phenotypes in Neurodegeneration and Innate Immunity

C. Cunningham, A. Dunne, A. Lopez-Rodriguez, 2018, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

Cytokines and the ageing brain

C. Cunningham, J. Konsman, T. Cartmell, 2002, Trends in Neurosciences.

Factors regulating microglia activation

W. Seaman, C. Cunningham, A. Sierra, 2013 .

A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1Β, TNF-α and IL-6 Challenges in C57BL/6 Mice

C. Cunningham, M. Dansereau, D. Skelly, 2013, PloS one.

The effect of non-steroidal anti-inflammatory agents on behavioural changes and cytokine production following systemic inflammation: Implications for a role of COX-1

V. Perry, C. Cunningham, T. Newman, 2010, Brain, Behavior, and Immunity.

Delirium

A. MacLullich, A. Slooter, E. Ely, 2020, Nature Reviews Disease Primers.

Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium

L. O. Watne, C. Cunningham, É. Griffin, 2020, The Journal of Neuroscience.

At the extreme end of the psychoneuroimmunological spectrum: Delirium as a maladaptive sickness behaviour response

A. MacLullich, C. Cunningham, 2013, Brain, Behavior, and Immunity.

A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank

D. Needham, E. Marcantonio, S. Inouye, 2020, Alzheimer's & dementia : the journal of the Alzheimer's Association.

International drive to illuminate delirium: A developing public health blueprint for action

R. Petersen, J. Karlawish, L. Fleisher, 2020, Alzheimer's & dementia : the journal of the Alzheimer's Association.

Delirium is a strong risk factor for dementia in the oldest-old: a population-based cohort study

Hannah Keage, Carol Brayne, Fiona E. Matthews, 2012, Brain : a journal of neurology.

Association of Delirium With Cognitive Decline in Late Life: A Neuropathologic Study of 3 Population-Based Cohort Studies

C. Brayne, B. Stephan, F. Matthews, 2017, JAMA psychiatry.

Prior Pathology in the Basal Forebrain Cholinergic System Predisposes to Inflammation-Induced Working Memory Deficits: Reconciling Inflammatory and Cholinergic Hypotheses of Delirium

C. Cunningham, A. Gossen, R. Field, 2012, The Journal of Neuroscience.

PriorPathologyintheBasalForebrainCholinergicSystem PredisposestoInflammation-InducedWorkingMemory Deficits:ReconcilingInflammatoryandCholinergic HypothesesofDelirium

C. Cunningham, 2012 .

Association of postoperative delirium with markers of neurodegeneration and brain amyloidosis: a pilot study

G. Frisoni, S. Morzenti, G. Annoni, 2018, Neurobiology of Aging.

Preclinical and translational models for delirium: Recommendations for future research from the NIDUS delirium network

R. de Cabo, R. Eckenhoff, E. Marcantonio, 2023, Alzheimer's & dementia : the journal of the Alzheimer's Association.

Correction: Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms

J. Rawlins, D. Bannerman, C. Cunningham, 2019, Molecular Psychiatry.

Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms

J. Rawlins, D. Bannerman, C. Cunningham, 2017, bioRxiv.

Systemic inflammation and delirium: important co-factors in the progression of dementia.

Colm Cunningham, C. Cunningham, 2011, Biochemical Society transactions.

Equipping staff to support people with an intellectual disability and dementia in care home settings

C. Cunningham, H. Wilkinson, D. Kerr, 2005 .

Synaptic changes characterize early behavioural signs in the ME7 model of murine prion disease

V. Perry, J. Rawlins, C. Cunningham, 2003, The European journal of neuroscience.

TGFβ1 regulates the inflammatory response during chronic neurodegeneration

V. Perry, C. Cunningham, D. Boche, 2006, Neurobiology of Disease.

Increased Brain Synthesis of Prostaglandin E2 and F2‐Isoprostane in Human and Experimental Transmissible Spongiform Encephalopathies

V. Perry, G. Levi, C. Cunningham, 2000, Journal of neuropathology and experimental neurology.

Influence of Enriched Environment on Viral Encephalitis Outcomes: Behavioral and Neuropathological Changes in Albino Swiss Mice

V. Perry, C. Cunningham, C. W. Picanço Diniz, 2011, PloS one.

Double stranded RNA drives anti-viral innate immune responses, sickness behavior and cognitive dysfunction dependent on dsRNA length, IFNAR1 expression and age

K. Mitchell, C. Cunningham, É. Griffin, 2021, Brain, Behavior, and Immunity.

Double stranded RNA drives innate immune responses, sickness behavior and cognitive impairment dependent on dsRNA length, IFNAR1 expression and age.

K. Mitchell, C. Cunningham, É. Griffin, 2021, bioRxiv.

Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression

Lei Jin, C. Cunningham, É. Griffin, 2019, Glia.

Atypical inflammation in the central nervous system in prion disease

C. Cunningham, D. Boche, H. Perry, 2002, Current opinion in neurology.

Malaise in the water maze: Untangling the effects of LPS and IL-1β on learning and memory

D. Sanderson, C. Cunningham, 2008, Brain, Behavior, and Immunity.

Cholinergic signalling in the forebrain controls microglial phenotype and responses to systemic inflammation

C. Cunningham, É. Griffin, J. Lowry, 2021, bioRxiv.

Acute neuroinflammation, sickness behavior and working memory responses to acute systemic LPS challenge following noradrenergic lesion in mice

C. Cunningham, É. Griffin, Ruairi O’Sullivan, 2020, Brain, Behavior, and Immunity.

Early Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficits in Three Distinct Strains of Prion Disease

V. Perry, R. Reynolds, C. Cunningham, 2013, PloS one.

Central and Systemic Endotoxin Challenges Exacerbate the Local Inflammatory Response and Increase Neuronal Death during Chronic Neurodegeneration

V. Perry, K. Lunnon, C. Cunningham, 2005, The Journal of Neuroscience.

Transforming growth factor-beta 1-mediated neuroprotection against excitotoxic injury in vivo.

V. Perry, C. Cunningham, J. Gauldie, 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Transforming growth factor β1, the dominant cytokine in murine prion disease: influence on inflammatory cytokine synthesis and alteration of vascular extracellular matrix

V. Perry, C. Cunningham, D. Boche, 2002, Neuropathology and applied neurobiology.

A single systemic inflammatory insult causes acute motor deficits and accelerates disease progression in a mouse model of human tauopathy

S. Chandran, A. MacLullich, C. Cunningham, 2019, Alzheimer's & dementia.

Systemic inflammation induces acute working memory deficits in the primed brain: relevance for delirium

J. Rawlins, D. Bannerman, D. Sanderson, 2012, Neurobiology of Aging.

Comparison of Inflammatory and Acute-Phase Responses in the Brain and Peripheral Organs of the ME7 Model of Prion Disease

Colm Cunningham, V. Perry, C. Cunningham, 2005, Journal of Virology.

At the centre of neuronal, synaptic and axonal pathology in murine prion disease: degeneration of neuroanatomically linked thalamic and brainstem nuclei

C. Cunningham, É. Griffin, E. Griffin, 2015, Neuropathology and applied neurobiology.

Mouse Behavioural Studies and What They Can Teach Us about Prion Diseases

C. Cunningham, 2005 .

Neuropathologically distinct prion strains give rise to similar temporal profiles of behavioral deficits

V. Perry, J. Rawlins, R. Deacon, 2005, Neurobiology of Disease.

Early behavioral changes and quantitative analysis of neuropathological features in murine prion disease

V. Perry, C. W. Picanço-Diniz, C. Cunningham, 2011, Prion.

SYSTEMIC INFLAMMATION AND DISEASE PROGRESSION IN ALZHEIMER DISEASE. AUTHORS' REPLY

V. Perry, C. Holmes, C. Cunningham, 2010 .

Systemic TNF-α produces acute cognitive dysfunction and exaggerated sickness behavior when superimposed upon progressive neurodegeneration

C. Cunningham, A. Lopez-Rodriguez, S. Gormley, 2017, Brain, Behavior, and Immunity.

Non-Steroidal Anti-Inflammatory Drugs and Cognitive Function: Are Prostaglandins at the Heart of Cognitive Impairment in Dementia and Delirium ?

C. Cunningham, D. Skelly, 2011, Journal of Neuroimmune Pharmacology.

A double dissociation between the effects of sub-pyrogenic systemic inflammation and hippocampal lesions on learning

V. Perry, J. Rawlins, D. Bannerman, 2009, Behavioural Brain Research.

Hippocampal Lesions can Enhance Discrimination Learning Despite Normal Sensitivity to Interference From Incidental Information

J. Rawlins, D. Bannerman, D. Sanderson, 2011, Hippocampus.

Design and dementia

C. Cunningham, J. Andrews, 2010 .

Supporting people with dementia in acute hospital settings.

C. Cunningham, C. Archibald, C Cunningham, 2006, Nursing standard (Royal College of Nursing (Great Britain) : 1987).

Microglial and Astrocyte priming in the APP/PS1 model of Alzheimer’s Disease: increased vulnerability to acute inflammation and cognitive deficits

C. Cunningham, A. Lopez-Rodriguez, Arshed Nazmi, 2018, bioRxiv.

Microglia and neurodegeneration: The role of systemic inflammation

C. Cunningham, 2013, Glia.

Evaluating the Clinical Impact of National Dementia Behaviour Support Programs on Neuropsychiatric Outcomes in Australia

C. Cunningham, Daniel Whiting, S. Macfarlane, 2021, Frontiers in Psychiatry.

Macrophages in the cochlea; an immunological link between risk factors and progressive hearing loss

C. Cunningham, T. Newman, C. Verschuur, 2021, Glia.

Systemic inflammation switches the inflammatory cytokine profile in CNS Wallerian degeneration

V. Perry, C. Cunningham, N. Platt, 2008, Neurobiology of Disease.

In vivo modification of tRNA with an artificial nucleobase leads to full disease remission in an animal model of multiple sclerosis

C. Cunningham, K. Mills, V. Kelly, 2016, Nucleic acids research.

Reply to Letter re: “The effect of non-steroidal anti-inflammatory agents on behavioural changes and cytokine production following systemic inflammation: Implications for a role of COX-1.” by Teeling et al.

V. Perry, C. Cunningham, T. Newman, 2011, Brain, Behavior, and Immunity.

Microglia in the degenerating brain are capable of phagocytosis of beads and of apoptotic cells, but do not efficiently remove PrPSc, even upon LPS stimulation

Colm Cunningham, V. Perry, C. Cunningham, 2010, Glia.

Specialist residential dementia care for people with severe and persistent behaviours: A ten‐year retrospective review

C. Cunningham, M. Gresham, Thomas Morris, 2021, Australasian journal on ageing.

Developing evaluation of signage for people with dementia

C. Cunningham, Liz Taylor, H. Wilkinson, 2019, Housing, Care and Support.

Understanding challenging behaviour in patients with dementia.

C. Cunningham, 2006, Nursing standard (Royal College of Nursing (Great Britain) : 1987).

Endogenous IL-1 in Cognitive Function and Anxiety: A Study in IL-1RI−/− Mice

D. Bannerman, C. Cunningham, P. Obiang, 2013, PloS one.

An animal model of delirium during dementia: Systemic inflammation induces acute working memory deficits in the primed brain

C. Cunningham, C. Murray, D. Skelly, 2010, Brain, Behavior, and Immunity.

Cyclooxygenase-1-Dependent Prostaglandins Mediate Susceptibility to Systemic Inflammation-Induced Acute Cognitive Dysfunction

C. Cunningham, É. Griffin, D. Skelly, 2013, The Journal of Neuroscience.

Systemic challenge with the TLR3 agonist poly I:C induces amplified IFN-α/β and IL-1β responses in the diseased brain and exacerbates chronic neurodegeneration

C. Cunningham, S. Campion, C. Murray, 2010, Brain, Behavior, and Immunity.

Publisher Correction: Delirium

A. MacLullich, A. Slooter, C. Cunningham, 2020, Nature Reviews Disease Primers.

The effect of baseline cognition and delirium on long-term cognitive impairment and mortality: a prospective population-based study

C. Brayne, N. Chaturvedi, K. Rockwood, 2022, The Lancet. Healthy longevity.

Exacerbation of CNS inflammation and neurodegeneration by systemic LPS treatment is independent of circulating IL-1β and IL-6

C. Cunningham, D. Skelly, C. Murray, 2011, Journal of Neuroinflammation.

Neuropil and neuronal changes in hippocampal NADPH‐diaphorase histochemistry in the ME7 model of murine prion disease

V. Perry, W. Gomes-Leal, C. W. Picanço-Diniz, 2004, Neuropathology and applied neurobiology.

When responsive and reactive meet organic? Treatment implications of language use in the era of #BanBPSD

C. Cunningham, S. Macfarlane, M. Atee, 2021, International journal of geriatric psychiatry.

Differential response of hippocampal and prefrontal oscillations to systemic LPS application

Md Nurul Islam, M. Tsanov, C. Cunningham, 2018, Brain Research.

Accessible design and dementia: A neglected space in the equality debate

T. Dunne, C. Cunningham, W. Mitchell, 2020, Dementia.

Litter size, age-related memory impairments, and microglial changes in rat dentate gyrus: Stereological analysis and three dimensional morphometry

C. W. Picanço-Diniz, C. Cunningham, A. Lopes, 2013, Neuroscience.

Pain in Dementia: Prevalence and Association with Neuropsychiatric Behaviours.

C. Cunningham, S. Macfarlane, M. Atee, 2020, Journal of pain and symptom management.

Losing Sleep Over Delirium.

C. Cunningham, R. Arora, 2018, Critical care medicine.

Systemic inflammation switches the inflammatory cytokine profile in CNS Wallerian degeneration

V. Perry, C. Cunningham, N. Platt, 2008, Neurobiology of Disease.

At the extreme end of the psychoneuroimmunological spectrum: Delirium as a maladaptive sickness behaviour response

A. MacLullich, C. Cunningham, 2013, Brain, Behavior, and Immunity.

Immune Stimulation and Cognitive Function: Defining the Deficits and Avoiding the Pitfalls

C. Cunningham, 2013 .

Ethical Considerations for Integrating Technology

Chris D. Nugent, Suzanne Martin, Colm Cunningham, 2007 .