K. Kumata

发表

[11C]DAC-PET for Noninvasively Monitoring Neuroinflammation and Immunosuppressive Therapy Efficacy in Rat Experimental Autoimmune Encephalomyelitis Model

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2012, Journal of Neuroimmune Pharmacology.

Synthesis and evaluation of 4-halogeno-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-[11C]methylbenzamide for imaging of metabotropic glutamate 1 receptor in melanoma.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2015, Journal of medicinal chemistry.

In vivo evaluation of P-glycoprotein and breast cancer resistance protein modulation in the brain using [(11)C]gefitinib.

I. Kanno, Ming-Rong Zhang, Kazutoshi Suzuki, 2009, Nuclear medicine and biology.

Synthesis and Evaluation of Novel Radioligands Based on 3-[5-(Pyridin-2-yl)-2H-tetrazol-2-yl]benzonitrile for Positron Emission Tomography Imaging of Metabotropic Glutamate Receptor Subtype 5.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2016, Journal of medicinal chemistry.

Synthesis and evaluation of novel radioligands for positron emission tomography imaging of metabotropic glutamate receptor subtype 1 (mGluR1) in rodent brain.

Lin Xie, Kazunori Kawamura, Toshimitsu Fukumura, 2012, Journal of medicinal chemistry.

Radiosynthesis and preliminary evaluation of 4-[18F]fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as a new positron emission tomography ligand for metabotropic glutamate receptor subtype 1.

Ming-Rong Zhang, Tomoteru Yamasaki, Joji Yui, 2011, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of 6-[1-(2-[(18)F]fluoro-3-pyridyl)-5-methyl-1H-1,2,3-triazol-4-yl]quinoline for positron emission tomography imaging of the metabotropic glutamate receptor type 1 in brain.

Ming-Rong Zhang, J. Maeda, Tomoteru Yamasaki, 2011, Bioorganic & medicinal chemistry.

[11C]Gefitinib ([11C]Iressa): Radiosynthesis, In Vitro Uptake, and In Vivo Imaging of Intact Murine Fibrosarcoma

Kazunori Kawamura, Jun Toyohara, Joji Yui, 2010, Molecular Imaging and Biology.

Utilization of [11C]phosgene for radiosynthesis of N-(2-{3-[3,5-bis(trifluoromethyl)]phenyl[11C]ureido}ethyl)glycyrrhetinamide, an inhibitory agent for proteasome and kinase in tumors.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2012, Bioorganic & medicinal chemistry letters.

Radiosynthesis of three [11C]ureido-substituted benzenesulfonamides as PET probes for carbonic anhydrase IX in tumors.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2011, Bioorganic & medicinal chemistry letters.

In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies.

Lu Wang, Lin Xie, Mary Jo Ondrechen, 2018, Journal of medicinal chemistry.

Radiosynthesis and evaluation of a novel monoacylglycerol lipase radiotracer: 1,1,1,3,3,3-hexafluoropropan-2-yl-3-(1-benzyl-1H-pyrazol-3-yl)azetidine-1-[11C]carboxylate.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2019, Bioorganic & medicinal chemistry.

A Facile Radiolabeling of [18F]FDPA via Spirocyclic Iodonium Ylides: Preliminary PET Imaging Studies in Preclinical Models of Neuroinflammation.

Steven H. Liang, Ming-Rong Zhang, K. Kumata, 2017, Journal of medicinal chemistry.

11C-AC-5216: A Novel PET Ligand for Peripheral Benzodiazepine Receptors in the Primate Brain

Tetsuya Suhara, Shigeru Obayashi, Akiko Hatori, 2007, Journal of Nuclear Medicine.

Synthesis of [11C]carbonyl-labeled cyclohexyl (5-(2-acetamidobenzo[d]thiazol-6-yl)-2-methylpyridin-3-yl)carbamate ([11C-carbonyl]PK68) as a potential PET tracer for receptor-interacting protein 1 kinase

Ming-Rong Zhang, Tomoteru Yamasaki, K. Kumata, 2022, EJNMMI Radiopharmacy and Chemistry.

Identification and Development of a New Positron Emission Tomography Ligand 4-(2-Fluoro-4-[11C]methoxyphenyl)-5-((1-methyl-1H-pyrazol-3-yl)methoxy)picolinamide for Imaging Metabotropic Glutamate Receptor Subtype 2 (mGlu2).

Steven H. Liang, Ming-Rong Zhang, D. Sheffler, 2020, Journal of medicinal chemistry.

3-(Cyclopropylmethyl)-7-((4-(4-[11C]methoxyphenyl)piperidin-1-yl)methyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine: Synthesis and Preliminary Evaluation for PET Imaging of Metabotropic Glutamate Receptor Subtype 2.

Ming-Rong Zhang, K. Kumata, Kuan Hu, 2020, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of 1-(cyclopropylmethyl)-4-(4-[11C]methoxyphenyl)-piperidin-1-yl-2-oxo-1,2-dihydropyridine-3-carbonitrile ([11C]CMDC) for PET imaging of metabotropic glutamate receptor 2 in the rat brain.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2017, Bioorganic & medicinal chemistry.

Development of a 18F-Labeled Radiotracer with Improved Brain Kinetics for Positron Emission Tomography Imaging of Translocator Protein (18 kDa) in Ischemic Brain and Glioma.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2017, Journal of medicinal chemistry.

Synthesis and evaluation of new (18)F-labelled acetamidobenzoxazolone-based radioligands for imaging of the translocator protein (18 kDa, TSPO) in the brain.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2014, Organic & biomolecular chemistry.

Characterization of a novel acetamidobenzoxazolone‐based PET ligand for translocator protein (18 kDa) imaging of neuroinflammation in the brain

Ming-Rong Zhang, J. Maeda, Lin Xie, 2014, Journal of neurochemistry.

Imaging of the translocator protein (18kDa) in rat brain after ischemia using [11C]DAC with ultra‐high specific activity

Kazunori Kawamura, Joji Yui, Akiko Hatori, 2010, Synapse.

Evaluation of N‐benzyl‐N‐[11C]methyl‐2‐ (7‐methyl‐8‐oxo‐2‐phenyl‐7,8‐dihydro‐9H‐purin‐9‐yl)acetamide ([11C]DAC) as a novel translocator protein (18 kDa) radioligand in kainic acid‐lesioned rat

Ming-Rong Zhang, O. Inoue, Kazutoshi Suzuki, 2009, Synapse.

N-(5-Fluoro-2-phenoxyphenyl)-N-(2-[(131)I]iodo-5-me thoxybenzyl)acetamide: a potent iodinated radioligand for the peripheral-type benzodiazepine receptor in brain.

Ming-Rong Zhang, C. Halldin, T. Suhara, 2007, Journal of medicinal chemistry.

18F-FEAC and 18F-FEDAC: PET of the Monkey Brain and Imaging of Translocator Protein (18 kDa) in the Infarcted Rat Brain

Kazunori Kawamura, Joji Yui, Akiko Hatori, 2010, The Journal of Nuclear Medicine.

Automated radiosynthesis of two 18F-labeled tracers containing 3-fluoro-2-hydroxypropyl moiety, [18F]FMISO and [18F]PM-PBB3, via [18F]epifluorohydrin

Ming-Rong Zhang, K. Kawamura, K. Kumata, 2021, EJNMMI Radiopharmacy and Chemistry.

Radiosynthesis of 18F-fluoroethylated tracers via a simplified one-pot 18F-fluoroethylation method using [18F]fluoroethyl tosylate.

Ming-Rong Zhang, K. Kawamura, K. Kumata, 2020, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis of two novel [18F]fluorobenzene-containing radiotracers via spirocyclic iodonium ylides and positron emission tomography imaging of translocator protein (18 kDa) in ischemic brain.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2018, Organic & biomolecular chemistry.

Comparison between [18F]fluorination and [18F]fluoroethylation reactions for the synthesis of the PDE10A PET radiotracer [18F]MNI-659.

Ming-Rong Zhang, M. Higuchi, K. Kawamura, 2017, Nuclear medicine and biology.

[18F]FEBMP: Positron Emission Tomography Imaging of TSPO in a Model of Neuroinflammation in Rats, and in vitro Autoradiograms of the Human Brain

Ming-Rong Zhang, J. Maeda, M. Higuchi, 2015, Theranostics.

[18F]FPBMP: – a potential new positron emission tomography radioligand for imaging of translocator protein (18 kDa) in peripheral organs of rats

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2015 .

PET Imaging of Lung Inflammation with [18F]FEDAC, a Radioligand for Translocator Protein (18 kDa)

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2012, PloS one.

Imaging of peripheral-type benzodiazepine receptor in tumor: in vitro binding and in vivo biodistribution of N-benzyl-N-[(11)C]methyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide.

Akiko Hatori, Kazuhiko Yanamoto, Tomoteru Yamasaki, 2009, Nuclear medicine and biology.

Binding potential of (E)-[¹¹C]ABP688 to metabotropic glutamate receptor subtype 5 is decreased by the inclusion of its ¹¹C-labelled Z-isomer.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2014, Nuclear medicine and biology.

Evaluation of the novel TSPO radiotracer 2-(7-butyl-2-(4-(2-([18F]fluoroethoxy)phenyl)-5-methylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide in a preclinical model of neuroinflammation.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2018, European journal of medicinal chemistry.

Multimodal Imaging for DREADD-Expressing Neurons in Living Brain and Their Application to Implantation of iPSC-Derived Neural Progenitors

B. Richmond, R. Shin, Ming-Rong Zhang, 2016, The Journal of Neuroscience.

Synthesis and evaluation of [11C]MMPIP as a potential radioligand for imaging of metabotropic glutamate 7 receptor in the brain

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2013, EJNMMI Research.

Monitoring Neuroprotective Effects Using Positron Emission Tomography With [11C]ITMM, a Radiotracer for Metabotropic Glutamate 1 Receptor

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2013, Stroke.

Synthesis and preliminary studies of a novel negative allosteric modulator [11C]QCA for imaging of metabotropic glutamate receptor 2

Steven H. Liang, Ming-Rong Zhang, D. Sheffler, 2017 .

A novel monoacylglycerol lipase-targeted 18F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network

Steven H. Liang, L. Josephson, Ming-Rong Zhang, 2022, Acta Pharmacologica Sinica.

Radiosynthesis and evaluation of 4-(6-[18F]Fluoro-4-(5-isopropoxy-1H-indazol-3-yl)pyridin-2-yl)morpholine as a novel radiotracer candidate targeting leucine-rich repeat kinase 2.

Ming-Rong Zhang, Tomoteru Yamasaki, K. Kumata, 2020, RSC medicinal chemistry.

Radiosynthesis and in vivo evaluation of 11C-labeled BMS-193885 and its desmethyl analog as PET tracers for neuropeptide Y1 receptors

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2019, EJNMMI Radiopharmacy and Chemistry.

[18F]DAA1106: Automated radiosynthesis using spirocyclic iodonium ylide and preclinical evaluation for positron emission tomography imaging of translocator protein (18 kDa).

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2018, Bioorganic & medicinal chemistry.

A useful PET probe [11C]BU99008 with ultra-high specific radioactivity for small animal PET imaging of I2-imidazoline receptors in the hypothalamus.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2017, Nuclear medicine and biology.

Radiosynthesis and preliminary PET evaluation of glycogen synthase kinase 3β (GSK-3β) inhibitors containing [(11)C]methylsulfanyl, [(11)C]methylsulfinyl or [(11)C]methylsulfonyl groups.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2015, Bioorganic & medicinal chemistry letters.

Development of the Fibronectin-Mimetic Peptide KSSPHSRN(SG)5RGDSP as a Novel Radioprobe for Molecular Imaging of the Cancer Biomarker α5β1 Integrin.

Ming-Rong Zhang, Y. Fujibayashi, T. Saga, 2015, Biological & pharmaceutical bulletin.

Imaging of Transmembrane AMPA Receptor Regulatory Proteins by Positron Emission Tomography.

Steven H. Liang, S. Tomita, Ming-Rong Zhang, 2022, Journal of medicinal chemistry.

Imaging the trace amine-associated receptor 1 by positron emission tomography

Steven H. Liang, Ming-Rong Zhang, K. Kumata, 2021 .

Positron Emission Tomography (PET) Imaging of Metabotropic Glutamate Receptor Subtype 2 (mGlu2) Based on a Negative Allosteric Modulator Radioligand

Steven H. Liang, L. Josephson, Ming-Rong Zhang, 2021 .

Synthesis and preliminary studies of 11C-labeled tetrahydro-1,7-naphthyridine-2-carboxamides for PET imaging of metabotropic glutamate receptor 2

Steven H. Liang, Ming-Rong Zhang, D. Sheffler, 2020, Theranostics.

Synthesis and evaluation of 6-(11C-methyl(4-(pyridin-2-yl)thiazol-2-yl)amino)benzo[d]thiazol-2(3H)-one for imaging γ-8 dependent transmembrane AMPA receptor regulatory protein by PET.

Steven H. Liang, L. Josephson, Ming-Rong Zhang, 2019, Bioorganic & medicinal chemistry letters.

Development of [(11)C]MFTC for PET imaging of fatty acid amide hydrolase in rat and monkey brains.

Ming-Rong Zhang, J. Maeda, Yuji Nagai, 2015, ACS chemical neuroscience.

[11C]sorafenib: radiosynthesis and preliminary PET study of brain uptake in P-gp/Bcrp knockout mice.

Ming-Rong Zhang, Tomoteru Yamasaki, Joji Yui, 2011, Bioorganic & medicinal chemistry letters.

In vivo evaluation of limiting brain penetration of probes for α(2C)-adrenoceptor using small-animal positron emission tomography.

Ming-Rong Zhang, Tomoteru Yamasaki, Joji Yui, 2010, ACS chemical neuroscience.

Developing new PET tracers to image the growth hormone secretagogue receptor 1a (GHS-R1a).

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2017, Nuclear medicine and biology.

Synthesis and evaluation of 4-(2-fluoro-4-[11C]methoxyphenyl)-5-((2-methylpyridin-4-yl)methoxy)picolinamide for PET imaging of the metabotropic glutamate receptor 2 in the rat brain.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2019, Bioorganic & medicinal chemistry.

Identification and Development of A New Positron Emission Tomography Ligand 4-(2-Fluoro-4-[ 11 C]methoxyphenyl)-5-((1-methyl-1 H -pyrazol-3-yl)methoxy)picolinamide for Imaging Metabotropic Glutamate Receptor Subtype 2 (mGlu 2 )

Steven H. Liang, Ming-Rong Zhang, D. Sheffler, 2021 .

Radiosynthesis of novel carbon-11-labeled triaryl ligands for cannabinoid-type 2 receptor.

Ming-Rong Zhang, J. Maeda, Tomoteru Yamasaki, 2010, Bioorganic & medicinal chemistry letters.

In vivo evaluation of a new ¹⁸F-labeled PET ligand, [¹⁸F]FEBU, for the imaging of I₂-imidazoline receptors.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2015, Nuclear medicine and biology.

imaging of I 2 -imidazoline receptors

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2015 .

In Vivo Positron Emission Tomographic Imaging of Glial Responses to Amyloid-β and Tau Pathologies in Mouse Models of Alzheimer's Disease and Related Disorders

J. Trojanowski, V. Lee, Ming-Rong Zhang, 2011, The Journal of Neuroscience.

[2-11C]isopropyl-, [1-11C]ethyl-, and [11C]methyl-labeled phenoxyphenyl acetamide derivatives as positron emission tomography ligands for the peripheral benzodiazepine receptor: radiosynthesis, uptake, and in vivo binding in brain.

Ming-Rong Zhang, T. Suhara, Kazutoshi Suzuki, 2006, Journal of medicinal chemistry.

Development of Novel 191Pt-Labeled Hoechst33258: 191Pt Is More Suitable than 111In for Targeting DNA

Ming-Rong Zhang, A. Kurimasa, K. Kumata, 2022, Journal of medicinal chemistry.

Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys

Samuel T. Slocum, Xi-Ping Huang, B. Roth, 2019, Nature Neuroscience.

Synthesis and Preliminary Evaluation of 11C‐Labeled VU0467485/AZ13713945 and Its Analogues for Imaging Muscarinic Acetylcholine Receptor Subtype 4

Steven H. Liang, L. Josephson, Ming-Rong Zhang, 2018, ChemMedChem.

Synthesis and evaluation of 1-[2-(4-[(11)C]methoxyphenyl)phenyl]piperazine for imaging of the serotonin 5-HT7 receptor in the rat brain.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2013, Bioorganic & medicinal chemistry.

PET study using [11C]FTIMD with ultra-high specific activity to evaluate I2-imidazoline receptors binding in rat brains.

Ming-Rong Zhang, Y. Kimura, Tomoteru Yamasaki, 2012, Nuclear medicine and biology.

Synthesis of N-(5-Aminopyrazol-3-yl)amino and N(5-Amino-1,2,4-triazol-3-yl)amino Acids

K. Kumata, M. Yokoyama, A. Kogo, 1988 .

Radiosynthesis of 13N-labeled thalidomide using no-carrier-added [13N]NH3

Ming-Rong Zhang, Kazutoshi Suzuki, Joji Yui, 2010 .

Scandium Triflate-Catalyzed N-[18F]Fluoroalkylation of Aryl- Or Heteroaryl-Amines with [18F]Epifluorohydrin under Mild Conditions.

Ming-Rong Zhang, Tomoteru Yamasaki, K. Kumata, 2022, Organic letters.

Visualization of Acute Liver Damage Induced by Cycloheximide in Rats Using PET with [18F]FEDAC, a Radiotracer for Translocator Protein (18 kDa)

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2014, PloS one.

Synthesis and preliminary evaluation of 4-hydroxy-6-(3-[11C]methoxyphenethyl)pyridazin-3(2H)-one, a 11C-labeled d-amino acid oxidase (DAAO) inhibitor for PET imaging.

Steven H. Liang, L. Josephson, Ming-Rong Zhang, 2020, Bioorganic & medicinal chemistry letters.

Preparation of some 1,3-selenazin-4-ones

K. Kumata, M. Yokoyama, H. Hatanaka, 1986 .

Synthesis and preliminary evaluation of 18F-labeled 1-(6,7-dimethyl-4-(methylamino)-1,3-dihydro-2H-pyrrolo[3,4-c]pyridin-2-yl)-2-(trans-2-(6-fluoropyridin-3-yl)cyclopropyl)ethan-1-one for imaging muscarinic acetylcholine receptor subtype 4

Steven H. Liang, L. Josephson, Ming-Rong Zhang, 2020 .

Molecular imaging of ectopic metabotropic glutamate 1 receptor in melanoma with a positron emission tomography radioprobe 18F‐FITM

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2014, International journal of cancer.

In vitro and ex vivo autoradiography studies on peripheral-type benzodiazepine receptor binding using [11C]AC-5216 in normal and kainic acid-lesioned rats

Akiko Hatori, Kazuhiko Yanamoto, Katsushi Kumata, 2007, Neuroscience Letters.

Radiosynthesis of [13N]dantrolene, a positron emission tomography probe for breast cancer resistant protein, using no-carrier-added [13N]ammonia.

Ming-Rong Zhang, Kazutoshi Suzuki, K. Kumata, 2012, Bioorganic & medicinal chemistry.

[(11)C-carbonyl]CEP-32496: radiosynthesis, biodistribution and PET study of brain uptake in P-gp/BCRP knockout mice.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2014, Bioorganic & medicinal chemistry letters.

Evaluation of Chemotherapy Response in VX2 Rabbit Lung Cancer with 18F-Labeled C2A Domain of Synaptotagmin I

Ming-Rong Zhang, Kazutoshi Suzuki, Tomoteru Yamasaki, 2011, The Journal of Nuclear Medicine.

Development of 1-N-11C-Methyl-l- and -d-Tryptophan for pharmacokinetic imaging of the immune checkpoint inhibitor 1-Methyl-Tryptophan

Ming-Rong Zhang, T. Suhara, J. Maeda, 2015, Scientific Reports.

Off-tumor IDO1 target engagements determine the cancer-immune set point and predict the immunotherapeutic efficacy

Ming-Rong Zhang, Yihai Cao, T. Shimokawa, 2021, Journal for ImmunoTherapy of Cancer.

Automated Synthesis of (rac)‐, (R)‐, and (S)‐[18F]Epifluorohydrin and Their Application for Developing PET Radiotracers Containing a 3‐[18F]Fluoro‐2‐hydroxypropyl Moiety

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2018, ChemMedChem.

Synthesis of nucleosides using ketene dithioacetals

K. Kumata, M. Yokoyama, Hidehiko Noro, 1988 .

Distinct binding of PET ligands PBB3 and AV-1451 to tau fibril strains in neurodegenerative tauopathies

Virginia M. Y. Lee, J. Trojanowski, D. Dickson, 2017, Brain : a journal of neurology.

Synthesis and Preliminary PET Imaging Studies of a FAAH Radiotracer ([¹¹C]MPPO) Based on α-Ketoheterocyclic Scaffold.

Steven H. Liang, Ming-Rong Zhang, Tomoteru Yamasaki, 2016, ACS chemical neuroscience.

Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a "Tail Switching" Strategy on a Piperazinyl Azetidine Skeleton.

Steven H. Liang, L. Josephson, Ming-Rong Zhang, 2019, Journal of medicinal chemistry.

Dynamic Changes in Striatal mGluR1 But Not mGluR5 during Pathological Progression of Parkinson's Disease in Human Alpha-Synuclein A53T Transgenic Rats: A Multi-PET Imaging Study

Lin Xie, Satoshi Shiomi, Hidekatsu Wakizaka, 2016, The Journal of Neuroscience.

Reduced serotonergic transmission alters sensitivity to cost and reward via 5-HT1A and 5-HT1B receptors in monkeys

Ming-Rong Zhang, T. Minamimoto, Y. Hori, 2023, bioRxiv.

Synthesis and Preliminary Studies of a Novel Negative Allosteric Modulator, 7-((2,5-Dioxopyrrolidin-1-yl)methyl)-4-(2-fluoro-4-[11C]methoxyphenyl) quinoline-2-carboxamide, for Imaging of Metabotropic Glutamate Receptor 2.

Steven H. Liang, Ming-Rong Zhang, D. Sheffler, 2017, ACS chemical neuroscience.

Synthesis and in vitro evaluation of three novel radiotracers for imaging of metabotropic glutamate receptor subtype 2 in rat brain.

Lin Xie, Tomoteru Yamasaki, K. Kumata, 2017, Bioorganic & medicinal chemistry letters.

Small-animal PET study for noninvasive quantification of transmembrane AMPA receptor regulatory protein γ-8 (TARP γ-8) in the brain

Steven H. Liang, Tomoteru Yamasaki, K. Kumata, 2023, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Noninvasive Quantification of Metabotropic Glutamate Receptor Type 1 with [11C]ITDM: a Small-Animal PET Study

Lin Xie, Hidekatsu Wakizaka, Kazunori Kawamura, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Visualization of early infarction in rat brain after ischemia using a translocator protein (18kDa) PET ligand [11C]DAC with ultra-high specific activity

Yuichiro Yoshida, Kazutoshi Suzuki, Kazunori Kawamura, 2011, NeuroImage.

A practical route for synthesizing a PET ligand containing [18F]fluorobenzene using reaction of diphenyliodonium salt with [18F]F−

Kazutoshi Suzuki, K. Kumata, Ming-Rong Zhang, 2007 .

[11C]DAC-PET for Noninvasively Monitoring Neuroinflammation and Immunosuppressive Therapy Efficacy in Rat Experimental Autoimmune Encephalomyelitis Model

Lin Xie, Tomoteru Yamasaki, N. Ichimaru, 2012, Journal of Neuroimmune Pharmacology.

Translocator protein (18 kDa), a potential molecular imaging biomarker for non-invasively distinguishing non-alcoholic fatty liver disease.

Lin Xie, Tomoteru Yamasaki, Joji Yui, 2012, Journal of hepatology.

In vivo imaging and quantitative analysis of TSPO in rat peripheral tissues using small-animal PET with [18F]FEDAC.

O. Inoue, Tomoteru Yamasaki, Joji Yui, 2010, Nuclear medicine and biology.

Imaging of peripheral-type benzodiazepine receptor in tumor: carbon ion irradiation reduced the uptake of a positron emission tomography ligand [11C]DAC in tumor.

Tomoteru Yamasaki, Joji Yui, K. Kawamura, 2010, Journal of radiation research.

PET imaging-guided chemogenetic silencing reveals a critical role of primate rostromedial caudate in reward evaluation

Yasuyuki Kimura, Ichio Aoki, Atsushi Fujimoto, 2016, Nature Communications.

N-(3,4-Dimethylisoxazol-5-yl)piperazine-4-[4-(2-fluoro-4-[(11)C]methylphenyl)thiazol-2-yl]-1-carboxamide: A promising positron emission tomography ligand for fatty acid amide hydrolase.

Lin Xie, Tomoteru Yamasaki, Joji Yui, 2016, Bioorganic & medicinal chemistry.

Assessment of radioligands for PET imaging of cyclooxygenase-2 in an ischemic neuronal injury model

H. Onoe, T. Suhara, M. Higuchi, 2013, Brain Research.

Synthesis and preliminary evaluation of novel 11C-labeled GluN2B-selective NMDA receptor negative allosteric modulators

Steven H. Liang, L. Josephson, Lin Xie, 2020, Acta Pharmacologica Sinica.

Development of 2-(2-(3-(4-([18F]Fluoromethoxy- d2)phenyl)-7-methyl-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)-4-isopropoxyisoindoline-1,3-dione for Positron-Emission-Tomography Imaging of Phosphodiesterase 10A in the Brain.

Lin Xie, Tomoteru Yamasaki, K. Kumata, 2018, Journal of medicinal chemistry.

Synthesis and preliminary evaluation of novel 11C-labeled GluN2B-selective NMDA receptor negative allosteric modulators

Steven H. Liang, L. Josephson, Lin Xie, 2020, Acta Pharmacologica Sinica.

Development of N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methyl-4-[11C]methylbenzamide for positron emission tomography imaging of metabotropic glutamate 1 receptor in monkey brain.

J. Maeda, Yuji Nagai, Lin Xie, 2012, Journal of medicinal chemistry.

Characterization of 1‐(2‐[18F]fluoro‐3‐pyridyl)‐4‐(2‐isopropyl‐1‐oxo‐ isoindoline‐5‐yl)‐5‐methyl‐1H‐1,2,3‐triazole, a PET ligand for imaging the metabotropic glutamate receptor type 1 in rat and monkey brains

T. Suhara, J. Maeda, Yuji Nagai, 2012, Journal of neurochemistry.

Utility of Translocator Protein (18 kDa) as a Molecular Imaging Biomarker to Monitor the Progression of Liver Fibrosis

Lin Xie, Tomoteru Yamasaki, Joji Yui, 2015, Scientific Reports.

Radiosynthesis and evaluation of 5-methyl-N-(4-[(11)C]methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine ([(11)C]ADX88178) as a novel radioligand for imaging of metabotropic glutamate receptor subtype 4 (mGluR4).

Lin Xie, Tomoteru Yamasaki, Joji Yui, 2016, Bioorganic & medicinal chemistry letters.

Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold.

Steven H. Liang, R. Carson, B. Cravatt, 2021, Journal of medicinal chemistry.

How to introduce radioactive chlorine into a benzene ring using [*Cl]Cl-?

Kazutoshi Suzuki, K. Kumata, M. Takei, 2008, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

The Glutaminase-1 Inhibitor [11C-carbony]BPTES: Synthesis and Positron Emission Tomography Study in Mice

Lin Xie, K. Kumata, Yiding Zhang, 2023, Pharmaceuticals.

Imaging α-synuclein pathologies in animal models and patients with Parkinson’s and related diseases

Ming-Rong Zhang, A. Kakita, M. Ichise, 2020, bioRxiv.

In vivo visualization of propagating α -synuclein pathologies in mouse and marmoset models by a bimodal imaging probe, C05-05

A. Kakita, T. Minamimoto, Yuji Nagai, 2021 .

[18F]FEAC and [18F]FEDAC: Two novel positron emission tomography ligands for peripheral-type benzodiazepine receptor in the brain.

Kazutoshi Suzuki, Tomoteru Yamasaki, Joji Yui, 2009, Bioorganic & medicinal chemistry letters.

In vivo imaging of designer receptor that enables to modify reward-related behavior in monkeys

Barry J. Richmond, Hiroyuki Kaneko, Yoko Kato, 2014 .

Efficient radiosynthesis and non-clinical safety tests of the TSPO radioprobe [(18)F]FEDAC: Prerequisites for clinical application.

Y. Fujibayashi, Lin Xie, Tomoteru Yamasaki, 2016, Nuclear medicine and biology.

Synthesis of two novel [18F]fluorobenzene-containing radiotracers via spirocyclic iodonium ylides and positron emission tomography imaging of translocator protein (18 kDa) in ischemic brain.

Lin Xie, Tomoteru Yamasaki, K. Kumata, 2018, Organic & biomolecular chemistry.

In Vivo Positron Emission Tomographic Imaging of Glial Responses to Amyloid-β and Tau Pathologies in Mouse Models of Alzheimer's Disease and Related Disorders

J. Trojanowski, V. Lee, T. Suhara, 2011, The Journal of Neuroscience.

Molecular imaging of ectopic metabotropic glutamate 1 receptor in melanoma with a positron emission tomography radioprobe 18F‐FITM

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