P. Mapp

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The impact of anxiety on chronic musculoskeletal pain and the role of astrocyte activation

A. Valdes, J. Stocks, D. Walsh, 2018, Pain.

Angiogenesis and nerve growth factor at the osteochondral junction in rheumatoid arthritis and osteoarthritis

D. Walsh, P. Mapp, D. McWilliams, 2010, Rheumatology.

Calcitonin gene‐related peptide in the joint: contributions to pain and inflammation

D. Walsh, P. Mapp, S. Kelly, 2015, British journal of clinical pharmacology.

Activation of the transcription factor nuclear factor-kappaB in human inflamed synovial tissue.

P. Baeuerle, P. Mapp, C. Kaltschmidt, 1996, Arthritis and rheumatism.

Lymphatic vessels in osteoarthritic human knees.

D. Walsh, P. Mapp, D. McWilliams, 2012, Osteoarthritis and cartilage.

Design, study quality and evidence of analgesic efficacy in studies of drugs in models of OA pain: a systematic review and a meta-analysis.

D. Walsh, P. Mapp, D. R. Sagar, 2014, Osteoarthritis and cartilage.

Innervation and neurokinin receptors during angiogenesis in the rat sponge granuloma

J. Polak, D. A. Walsh, P. Mapp, 1996, The Histochemical Journal.

Neurogenic influences on contralateral responses during experimental rat monoarthritis

P. Mapp, S. Cruwys, B. Kidd, 1995, Brain Research.

Augmented pain behavioural responses to intra-articular injection of nerve growth factor in two animal models of osteoarthritis

D. Walsh, J. Burston, P. Mapp, 2013, Annals of the rheumatic diseases.

Differences in structural and pain phenotypes in the sodium monoiodoacetate and meniscal transection models of osteoarthritis

D. Walsh, J. Burston, P. Mapp, 2012, Osteoarthritis and cartilage.

Effects of a metalloproteinase inhibitor on osteochondral angiogenesis, chondropathy and pain behavior in a rat model of osteoarthritis

R. Maciewicz, D. Walsh, P. Mapp, 2010, Osteoarthritis and cartilage.

Neuropeptide degrading enzymes in normal and inflamed human synovium.

J. Polak, D. A. Walsh, J. Wharton, 1993, The American journal of pathology.

Localization of the enzyme neutral endopeptidase to the human synovium.

J. Polak, D. A. Walsh, P. Mapp, 1992, The Journal of rheumatology.

The anti-NGF antibody muMab 911 both prevents and reverses pain behaviour and subchondral osteoclast numbers in a rat model of osteoarthritis pain

D. Walsh, J. Burston, P. Mapp, 2016, Osteoarthritis and cartilage.

Autoradiographic localization and characterization of [3H]alpha-trinositol (1D-myo-inositol 1,2,6-trisphosphate) binding sites in human and mammalian tissues.

J. Polak, D. A. Walsh, P. Mapp, 1995, The Journal of pharmacology and experimental therapeutics.

Therapeutic Benefit for Late, but Not Early, Passage Mesenchymal Stem Cells on Pain Behaviour in an Animal Model of Osteoarthritis

A. E. El Haj, H. Markides, J. Burston, 2017, Stem cells international.

Localization of 3-nitrotyrosine to rheumatoid and normal synovium.

P. Gallagher, D. A. Walsh, P. Mapp, 2001, Arthritis and rheumatism.

Role of substance P in inflammatory arthritis.

P. Mapp, S. Cruwys, B. Kidd, 1992, Annals of the rheumatic diseases.

Mechanisms and targets of angiogenesis and nerve growth in osteoarthritis

D. Walsh, P. Mapp, 2012, Nature Reviews Rheumatology.

A role for the sensory neuropeptide calcitonin gene‐related peptide in endothelial cell proliferation in vivo

D. Walsh, P. Mapp, D. McWilliams, 2012, British journal of pharmacology.

Focally regulated endothelial proliferation and cell death in human synovium.

D. A. Walsh, P. Mapp, M. Wade, 1998, The American journal of pathology.

Innervation of the synovium.

P. Mapp, 1995, Annals of the rheumatic diseases.

Autoradiographic localization and analysis of endothelin-1 binding sites in human synovial tissue.

R. A. Rutherford, J. Polak, D. A. Walsh, 1992, Arthritis and rheumatism.

Localisation and characterisation of substance P binding to human synovial tissue in rheumatoid arthritis.

R. A. Rutherford, J. Polak, D. A. Walsh, 1992, Annals of the rheumatic diseases.

on nerve fibres in the synovium . Effect of three animal models of inflammation

J. Polak, D. Walsh, P. Mapp, 2022 .

16 – Neuropeptides and the Synovium

P. Mapp, D. Blake, 1995 .

Microvascular substance P binding to normal and inflamed rat and human synovium.

J. Polak, D. A. Walsh, J. Wharton, 1993, The Journal of pharmacology and experimental therapeutics.

Sympathetic nervous system in chronic joint

P. Mapp, S. Cruwys, B. Kidd, 2004 .

Effect of three animal models of inflammation on nerve fibres in the synovium.

J. Polak, D. A. Walsh, P. Mapp, 1994, Annals of the rheumatic diseases.

Monoarthritis in the rat knee induces bilateral and time-dependent changes in substance P and calcitonin gene-related peptide immunoreactivity in the spinal cord

D. A. Walsh, D. Walsh, P. Mapp, 1993, Neuroscience.

arthritis . Role of substance P in inflammatory

P. Mapp, S. Cruwys, B. Kidd, 2022 .

The transcription factors hypoxia-inducible factor 1alpha and Ets-1 colocalize in the hypoxic synovium of inflamed joints in adjuvant-induced arthritis.

C. Lewis, P. Mapp, C. Morris, 2004, Arthritis and rheumatism.

The effect of intra-articular capsaicin on nerve fibres within the synovium of the rat knee joint

P. Mapp, D. Blake, S. Brain, 1996, Journal of Chemical Neuroanatomy.

A review of contralateral responses to a unilateral inflammatory lesion.

N. Shenker, P. Mapp, D. Blake, 2003, Rheumatology.

Lewis rats . initiates spontaneous recurrent flares in PPD and hsp 65 induced monoarthritis

P. Mapp, C. Morris, D. Blake, 2004 .

PPD and hsp65 induced monoarthritis initiates spontaneous recurrent flares in Lewis rats.

P. Mapp, C. Morris, D. Blake, 1995, Annals of the rheumatic diseases.

SYNOVIAL FLUID T CELLS AND 65 kD HEAT-SHOCK PROTEIN

P. Mapp, P. Bacon, D. Blake, 1988, The Lancet.

Fibronectin production by synovial intimal cells

P. Mapp, P. Revell, 2004, Rheumatology International.

Control of oxidative damage in rheumatoid arthritis by gold(I)-thiolate drugs.

P. Mapp, M. Grootveld, D. Blake, 1990, Free radical research communications.

Mechanisms of persistent synovitis.

P. Mapp, C. Morris, B. Kidd, 1988, Scandinavian journal of rheumatology. Supplement.

Assessment of endothelial function in complex regional pain syndrome type I using iontophoresis and laser Doppler imaging.

N. Shenker, N. Harris, P. Mapp, 2005, Rheumatology.

The synovial membrane in osteoarthritis: a histological study including the characterisation of the cellular infiltrate present in inflammatory osteoarthritis using monoclonal antibodies.

P. Mapp, P. Revell, P. Lalor, 1988, Annals of the rheumatic diseases.

Osteochondral angiogenesis and increased protease inhibitor expression in OA

D. Walsh, P. Mapp, D. McWilliams, 2010, Osteoarthritis and cartilage.

Angiogenesis in two animal models of osteoarthritis.

R. Webster, D. Walsh, P. Mapp, 2008, Osteoarthritis and cartilage.

Activation of the transcription factor NF-kB in inflamed synovial tissue

P. Baeuerle, P. Mapp, C. Kaltschmidt, 1996 .

Ultrastructural localisation of muramidase in the human synovial membrane.

P. Mapp, P. Revell, 1987, Annals of the rheumatic diseases.

Thesynovial membrane inosteoarthritis: a histological study including thecharacterisation ofthe cellular infiltrate present ininflammatory osteoarthritis using monoclonal antibodies

P. Mapp, P. Revell, P. Lalor, 1988 .

Increased vascular penetration and nerve growth in the meniscus: a potential source of pain in osteoarthritis

D. Walsh, P. Mapp, Deborah Wilson, 2010, Annals of the rheumatic diseases.

Relationship between structural pathology and pain behaviour in a model of osteoarthritis (OA)

D. Walsh, P. Mapp, V. Chapman, 2016, Osteoarthritis and cartilage.

Targeting the D Series Resolvin Receptor System for the Treatment of Osteoarthritis Pain

D. Barrett, J. Burston, P. Mapp, 2017, Arthritis & rheumatology.

Contributions of angiogenesis to inflammation, joint damage, and pain in a rat model of osteoarthritis.

D. Walsh, P. Mapp, S. Ashraf, 2011, Arthritis and rheumatism.

Fibronectin in the synovium of chronic inflammatory joint disease

P. Mapp, P. Revell, P. Davies, 2004, Rheumatology International.

Contralateral hyperalgesia and allodynia following intradermal capsaicin injection in man

N. Shenker, P. Mapp, D. Blake, 2008, Rheumatology.

Robust anti‐nociceptive effects of monoacylglycerol lipase inhibition in a model of osteoarthritis pain

B. Cravatt, D. Barrett, D. Walsh, 2016, British journal of pharmacology.

Hypoxia, oxidative stress and rheumatoid arthritis.

P. Mapp, M. Grootveld, D. Blake, 1995, British medical bulletin.

Ultrastructural characterisation of macrophages (type A cells) in the synovial lining

P. Mapp, P. Revell, P. I. Mapp, 2004, Rheumatology International.

Angiogenesis and the persistence of inflammation in a rat model of proliferative synovitis.

D. Walsh, P. Mapp, S. Ashraf, 2010, Arthritis and rheumatism.

Isolectin b4 binding neurons are not present in the rat knee joint

I. Chessell, P. Mapp, D. Blake, 2004, Neuroscience.

Substance P-, calcitonin gene-related peptide-and C-flanking peptide of neuropeptide Y-immunoreactive fibres are present in normal synovium but depleted in patients with rheumatoid arthritis

J. Polak, P. Mapp, P. Revell, 1990, Neuroscience.

Neurogenic influences in arthritis.

J. Polak, P. Mapp, B. Kidd, 1990, Annals of the rheumatic diseases.

The effects of calcitonin gene‐related peptide on formation of intra‐articular oedema by inflammatory mediators

D. A. Walsh, P. Mapp, S. Cruwys, 1992, British journal of pharmacology.

A NEUROGENIC MECHANISM FOR SYMMETRICAL ARTHRITIS

J. Polak, P. Mapp, B. Kidd, 1989, The Lancet.

Pain, neurogenic inflammation and symmetry in medical practice

N. Shenker, P. Mapp, D. Blake, 2001 .

Histopathological subgroups in knee osteoarthritis.

B. Moreton, E. Ferguson, D. Walsh, 2016, Osteoarthritis and cartilage.

Role of the sympathetic nervous system in chronic joint pain and inflammation.

P. Mapp, S. Cruwys, B. Kidd, 1992, Annals of the rheumatic diseases.

The role of substance P in rheumatic disease

P. Mapp, B. Kidd, 1994 .

AB0107 Influence of cobalt (II) + and chromium (III)-ions on bone formation in human osteoblast-like cells in-vitro

D. Walsh, P. Mapp, S. Ashraf, 2018, Osteoarthritis and cartilage.

Refining surgical models of osteoarthritis in mice and rats alters pain phenotype but not joint pathology

D. Walsh, J. Burston, P. Mapp, 2020, PloS one.

Structural Associations of Symptomatic Knee Osteoarthritis

D. Walsh, P. Mapp, B. Scammell, 2014, Arthritis & rheumatology.

Pain fibers in osteoarthritis: a review.

S. Santavirta, J. Polak, Y. Konttinen, 1989, Seminars in arthritis and rheumatism.

Joint physiology and synovial cell proliferation.

D. A. Walsh, P. Mapp, 1998, British Journal of Rheumatology.

Inactivation of xanthine oxidoreductase is associated with increased joint swelling and nitrotyrosine formation in acute antigen-induced arthritis.

P. Mapp, D. Blake, R. Klocke, 2005, Clinical and experimental rheumatology.

Proliferative activity of cells in the synovium as demonstrated by a monoclonal antibody, Ki67

P. Mapp, P. Revell, P. Lalor, 2004, Rheumatology International.

A role for the sensory neuropeptide calcitonin gene‐related peptide in endothelial cell proliferation in vivo

D. Walsh, P. Mapp, D. McWilliams, 2012, British journal of pharmacology.

Autoradiographic localisation and characterisation of substance P binding sites in rat knees

J. Polak, D. A. Walsh, J. Wharton, 1992, Regulatory Peptides.

Ultrastructural localisation ofmuramidase inthe humansynovial membrane

P. Mapp, P. Revell, 2011 .

Contributions of angiogenesis to inflammation, joint damage, and pain in a rat model of osteoarthritis.

D. Walsh, P. Mapp, S. Ashraf, 2011, Arthritis and rheumatism.

Blocking the tropomyosin receptor kinase A (TrkA) receptor inhibits pain behaviour in two rat models of osteoarthritis

D. Walsh, P. Mapp, V. Chapman, 2015, Annals of the rheumatic diseases.

Innervation of the synovium.

P. Mapp, 1995, Annals of the rheumatic diseases.

A monoclonal antibody (Mab 67) marks type B synoviocytes

P. Mapp, P. Revell, C. R. Stevens, 2005, Rheumatology International.

Synovial fluid fibronectin fragments: No evidence for a mitogenic effect on fibroblasts

P. Mapp, P. Revell, D. Scott, 2005, Rheumatology International.