G. Christensen

发表

Psychological distress and mortality in patients with acute dyspnea: data from the Akershus Cardiac Examination (ACE) 2 Study.

T. Dammen, G. Einvik, A. Høiseth, 2015, General hospital psychiatry.

Pentosan Polysulfate Decreases Myocardial Expression of the Extracellular Matrix Enzyme ADAMTS4 and Improves Cardiac Function In Vivo in Rats Subjected to Pressure Overload by Aortic Banding

C. Carlson, I. Sjaastad, G. Christensen, 2014, PloS one.

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.

G. Christensen, P. Aukrust, T. Espevik, 2013, Cardiovascular research.

Slowed relaxation and preserved maximal force in soleus muscles of mice with targeted disruption of the Serca2 gene in skeletal muscle

Ø. Ellingsen, O. Sejersted, G. Christensen, 2011, The Journal of physiology.

Mid-regional pro-adrenomedullin in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study.

A. Høiseth, J. Brynildsen, G. Christensen, 2017, Clinical biochemistry.

Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure.

C. Carlson, I. Sjaastad, G. Christensen, 2012, Physiological genomics.

Moderate Loss of the Extracellular Matrix Proteoglycan Lumican Attenuates Cardiac Fibrosis in Mice Subjected to Pressure Overload

I. Sjaastad, G. Christensen, I. G. Lunde, 2020, Cardiology.

The Heparan Sulfate Proteoglycan Glypican-6 Is Upregulated in the Failing Heart, and Regulates Cardiomyocyte Growth through ERK1/2 Signaling

I. Sjaastad, G. Christensen, I. G. Lunde, 2016, PloS one.

The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart

A. McCulloch, G. Christensen, I. G. Lunde, 2017, Journal of clinical medicine.

Circulating Secretoneurin Concentrations After Cardiac Surgery: Data From the FINNish Acute Kidney Injury Heart Study

V. Pettilä, S. Nygård, M. Stridsberg, 2019, Critical care medicine.

Chromogranin B in Heart Failure: A Putative Cardiac Biomarker Expressed in the Failing Myocardium

C. Carlson, I. Sjaastad, M. Stridsberg, 2010, Circulation. Heart failure.

In active juvenile dermatomyositis, elevated eotaxin and MCP-1 and cholesterol levels in the upper normal range are associated with cardiac dysfunction.

I. Sjaastad, G. Christensen, M. Vistnes, 2014, Rheumatology.

[Diagnostic accuracy for heart failure – data from the Akershus Cardiac Examination 2 Study].

S. Nygård, A. Høiseth, J. Brynildsen, 2015, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke.

Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart.

W. Linke, I. Sjaastad, G. Christensen, 2015, Cardiovascular research.

Cortisol response to stress is associated with myocardial remodeling in salmonid fishes

G. Christensen, H. Røsjø, G. Nilsson, 2011, Journal of Experimental Biology.

Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice

I. Sjaastad, G. Christensen, P. Aukrust, 2017, Mediators of inflammation.

Chromogranin B in Heart FailureClinical Perspective

C. Carlson, I. Sjaastad, M. Stridsberg, 2010 .

Elevated Levels of Activin A in Heart Failure: Potential Role in Myocardial Remodeling

G. Christensen, S. Frøland, T. Ueland, 2004, Circulation.

Alterations in circulating activin A, GDF‐15, TGF‐β3 and MMP‐2, ‐3, and ‐9 during one year of left ventricular reverse remodelling in patients operated for severe aortic stenosis

J. Pepper, G. Christensen, T. Tønnessen, 2008, European journal of heart failure.

Performance of a Novel Research-Use-Only Secretoneurin ELISA in Patients with Suspected Acute Coronary Syndrome: Comparison with an Established Secretoneurin Radioimmunoassay

M. Stridsberg, A. Høiseth, G. Christensen, 2021, Cardiology.

Diagnostic and prognostic properties of procalcitonin in patients with acute dyspnea: Data from the ACE 2 Study.

G. Einvik, A. Høiseth, J. Brynildsen, 2018, Clinical biochemistry.

Dephosphorylation of cardiac proteins in vitro – a matter of phosphatase specificity

J. V. Van Eyk, G. Christensen, G. Agnetti, 2012, Proteomics.

Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice.

I. Sjaastad, G. Christensen, P. Aukrust, 2015, American journal of physiology. Lung cellular and molecular physiology.

Syndecan-4–/– Mice Have Smaller Muscle Fibers, Increased Akt/mTOR/S6K1 and Notch/HES-1 Pathways, and Alterations in Extracellular Matrix Components

C. Carlson, K. Liland, I. Sjaastad, 2020, Frontiers in Cell and Developmental Biology.

Syndecan-4-/- mice have smaller muscle fibers, increased Akt/mTOR/S6K1 and Notch/HES-1 pathways, and alterations in extracellular matrix components

C. Carlson, K. Liland, I. Sjaastad, 2020, bioRxiv.

Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan‐4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure‐overloaded heart

C. Carlson, I. Sjaastad, G. Christensen, 2013, The FEBS journal.

Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models.

I. Sjaastad, K. Chien, O. Sejersted, 2009, Cell calcium.

Time Course of Degradation of Cardiac Troponin I in Patients With Acute ST-Elevation Myocardial Infarction: The ASSENT-2 Troponin Substudy

D. Atar, A. Jaffe, C. Granger, 2006, Circulation research.

The cardiokine secreted Frizzled‐related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure

L. Tavazzi, R. Latini, G. Christensen, 2014, Journal of internal medicine.

Increased cardiac expression of endothelin-1 mRNA in ischemic heart failure in rats.

O. Smiseth, O. Sejersted, G. Christensen, 1997, Cardiovascular research.

Dysregulated Osteoprotegerin/RANK Ligand/RANK Axis in Clinical and Experimental Heart Failure

G. Christensen, S. Frøland, T. Ueland, 2005, Circulation.

Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2.

Frode Willoch, I. Sjaastad, O. Sejersted, 2014, American journal of physiology. Heart and circulatory physiology.

isoforms in cardiomyocytes calcineurin-dependent NFAT transcription factor Angiotensin II and norepinephrine activate specific

W. Linke, I. Sjaastad, G. Christensen, 2015 .

Angiotensin II and norepinephrine activate specific calcineurin-dependent NFAT transcription factor isoforms in cardiomyocytes.

C. Carlson, G. Christensen, H. Kvaløy, 2011, Journal of applied physiology.

Prevalence and Prognostic Significance of Hyponatremia in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Data from the Akershus Cardiac Examination (ACE) 2 Study

J. Verbalis, A. Høiseth, J. Brynildsen, 2016, PloS one.

pump Capacity in Congestive Heart Failure Following Myocardial Infarction in Rats

O. Sejersted, G. Christensen, T. Tønnessen, 1998 .

Monocyte chemoattractant protein-1 enhances and interleukin-10 suppresses the production of inflammatory cytokines in adult rat cardiomyocytes

O. Sejersted, G. Christensen, T. Ueland, 2001, Basic Research in Cardiology.

Myocardial expression of CC- and CXC-chemokines and their receptors in human end-stage heart failure.

G. Christensen, S. Frøland, T. Ueland, 2000, Cardiovascular research.

Increased Production of CXCL16 in Experimental and Clinical Heart FailureCLINICAL PERSPECTIVE

G. Christensen, S. Aakhus, T. Ueland, 2009 .

Increased Production of CXCL16 in Experimental and Clinical Heart Failure: A Possible Role in Extracellular Matrix Remodeling

G. Christensen, S. Aakhus, T. Ueland, 2009, Circulation. Heart failure.

nonischemic murine heart failure Separate mechanisms cause anemia in ischemic vs.

P. Iversen, I. Sjaastad, O. Sejersted, 2011 .

Reduced immune responses to an aseptic inflammation in mice with congestive heart failure

P. Iversen, G. Christensen, P. Woldbaek, 2005, European journal of haematology.

Cytokine expression profiling of the myocardium reveals a role for CX3CL1 (fractalkine) in heart failure.

A. Frigessi, S. Nygård, G. Christensen, 2008, Journal of molecular and cellular cardiology.

Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in mice.

C. Carlson, I. Sjaastad, G. Christensen, 2015, Cardiovascular research.

Cytokine expression profiling of the myocardium reveals a role for CX3CL1 in heart failure

A. Frigessi, S. Nygård, G. Christensen, 2007 .

Glycosylated Chromogranin A in Heart FailureCLINICAL PERSPECTIVE

C. Carlson, I. Sjaastad, M. Stridsberg, 2017 .

Secretoneurin is a novel prognostic cardiovascular biomarker associated with cardiomyocyte calcium handling.

C. Carlson, I. Sjaastad, V. Pettilä, 2015, Journal of the American College of Cardiology.

Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout

C. Franzini-armstrong, O. Sejersted, G. Christensen, 2012, Proceedings of the National Academy of Sciences.

Results Development of Microsurgical Technology for the Delivery of Recombinant Adenoviruses Via Direct Intracardiac Chamber Injection in Living Murine Embryos

K. Chien, P. Gruber, Yibin Wang, 1999 .

Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice

I. Sjaastad, G. Christensen, P. Aukrust, 2015, PloS one.

Circulating cytokine levels in mice with heart failure are etiology dependent.

I. Sjaastad, S. Nygård, G. Christensen, 2010, Journal of applied physiology.

Cardiomyocyte-specific disruption of Serca2 in adult mice causes sarco(endo)plasmic reticulum stress and apoptosis.

Xiuhua Liu, G. Christensen, W. Louch, 2011, Cell calcium.

Prognostic and diagnostic significance of copeptin in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 study

S. Nygård, A. Høiseth, J. Brynildsen, 2017, Respiratory Research.

Decorin, lumican, and their GAG chain-synthesizing enzymes are regulated in myocardial remodeling and reverse remodeling in the mouse.

I. Sjaastad, G. Christensen, P. Aukrust, 2013, Journal of applied physiology.

Inhibition of SMAD2 phosphorylation preserves cardiac function during pressure overload.

I. Sjaastad, G. Christensen, W. Louch, 2012, Cardiovascular research.

Leukemia inhibitory factor reduces contractile function and induces alterations in energy metabolism in isolated cardiomyocytes.

G. Christensen, K. Andersson, G. Florholmen, 2004, Journal of molecular and cellular cardiology.

Myocardial gene expression of leukaemia inhibitory factor, interleukin‐6 and glycoprotein 130 in end‐stage human heart failure

G. Christensen, S. Frøland, P. Aukrust, 2001, European journal of clinical investigation.

Lack of Chemokine Signaling through CXCR5 Causes Increased Mortality, Ventricular Dilatation and Deranged Matrix during Cardiac Pressure Overload

I. Sjaastad, S. Nygård, G. Christensen, 2011, PloS one.

Transient, isopeptide-specific induction of myocardial endothelin-1 mRNA in congestive heart failure in rats.

O. Smiseth, G. Christensen, T. Tønnessen, 1997, American journal of physiology. Heart and circulatory physiology.

Decreased hematopoiesis in bone marrow of mice with congestive heart failure.

P. Iversen, G. Christensen, T. Tønnessen, 2002, American journal of physiology. Regulatory, integrative and comparative physiology.

Wnt5a is elevated in heart failure and affects cardiac fibroblast function

G. Christensen, S. Aakhus, T. Lekva, 2017, Journal of Molecular Medicine.

Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy

G. Christensen, S. Aakhus, T. Ueland, 2017, Scientific Reports.

Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation.

I. Sjaastad, S. Jonasson, G. Christensen, 2011, American journal of physiology. Lung cellular and molecular physiology.

IL-18 and IL-12 synergy induces matrix degrading enzymes in the lung

G. Christensen, O. Skjønsberg, E. Løberg, 2012, Experimental lung research.

pulmonary hypertension Elevated levels of activin A in clinical and experimental

I. Sjaastad, S. Jonasson, G. Christensen, 2015 .

Elevated levels of activin A in clinical and experimental pulmonary hypertension.

I. Sjaastad, G. Christensen, T. Ueland, 2009, Journal of applied physiology.

Sacubitril/valsartan ameliorates cardiac hypertrophy and preserves diastolic function in cardiac pressure overload

I. Sjaastad, G. Christensen, A. Cataliotti, 2021, ESC heart failure.

The Homeostatic Chemokine CCL21 Predicts Mortality and May Play a Pathogenic Role in Heart Failure

K. Dickstein, I. Sjaastad, G. Christensen, 2012, PloS one.

Circulating secretoneurin concentrations in patients with moderate to severe aortic stenosis.

T. Edvardsen, M. Stridsberg, J. Brynildsen, 2019, Clinical biochemistry.

Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure.

K. Dickstein, G. Christensen, J. Kjekshus, 2009, European heart journal.

Effect of short- and long-term physical activities on circulating granin protein levels

K. Godang, M. Stridsberg, G. Christensen, 2013, Regulatory Peptides.

The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload

I. Sjaastad, S. Nygård, G. Christensen, 2019, Scientific Reports.

Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia

C. Carlson, I. Sjaastad, S. Lehnart, 2019, Circulation. Arrhythmia and electrophysiology.

Prognostic Value of Secretoneurin in Patients With Severe Sepsis and Septic Shock: Data From the Albumin Italian Outcome Sepsis Study

A. Pesenti, R. Latini, M. Stridsberg, 2018, Critical care medicine.

Prognostic Value of Secretoneurin in Critically Ill Patients With Infections

E. Ruokonen, V. Pettilä, S. Nygård, 2016, Critical care medicine.

Prognostic Value of Secretoneurin in Patients with Acute Respiratory Failure: Data from the FINNALI Study.

V. Pettilä, S. Nygård, M. Stridsberg, 2016, Clinical chemistry.

Overexpression of integrin α11 induces cardiac fibrosis in mice

I. Sjaastad, H. Danielsen, G. Christensen, 2018, Acta physiologica.

Cardiopulmonary alterations in mRNA expression for interleukin‐1β, the interleukin‐6 superfamily and CXC‐chemokines during development of postischaemic heart failure in the rat

G. Christensen, T. Tønnessen, G. Florholmen, 2003, Clinical physiology and functional imaging.

Syndecan‐4 Protects the Heart From the Profibrotic Effects of Thrombin‐Cleaved Osteopontin

A. McCulloch, C. Carlson, I. Sjaastad, 2020, Journal of the American Heart Association.

Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress.

C. Carlson, I. Sjaastad, G. Christensen, 2013, Journal of molecular and cellular cardiology.

Shedding of syndecan-4 promotes immune cell recruitment and mitigates cardiac dysfunction after lipopolysaccharide challenge in mice.

I. Sjaastad, G. Christensen, J. M. Aronsen, 2015, Journal of molecular and cellular cardiology.

Increased syndecan expression following myocardial infarction indicates a role in cardiac remodeling.

Jian Li, G. Christensen, T. Lyberg, 2004, Physiological genomics.

Genomics Theis Tønnessen and Geir Christensen Alexandra Vanessa Finsen , Per Reidar Woldbaek , Jian Li , Jiaping Wu , Torstein Lyberg , infarction indicates a role in cardiac remodeling Increased syndecan expression following myocardial

Jian Li, G. Christensen, T. Lyberg, 2003 .

Glycosylated Chromogranin A: Potential Role in the Pathogenesis of Heart Failure

G. Christensen, T. Omland, H. Røsjø, 2017, Current Heart Failure Reports.

High-intensity exercise training in mice with cardiomyocyte-specific disruption of Serca2.

Ø. Ellingsen, B. Amundsen, I. Sjaastad, 2010, Journal of applied physiology.

SERCA2 activity is involved in the CNP‐mediated functional responses in failing rat myocardium

I. Sjaastad, G. Christensen, K. Hougen, 2013, British journal of pharmacology.

Circulating chromogranin B levels in patients with acute respiratory failure: data from the FINNALI Study

V. Pettilä, S. Nygård, M. Stridsberg, 2017, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

Cardiac Troponin I Degradation in Serum of Patients with Hypertrophic Obstructive Cardiomyopathy Undergoing Percutaneous Septal Ablation

D. Atar, Z. Grieg, G. Christensen, 2009, Cardiology.

The female syndecan-4−/− heart has smaller cardiomyocytes, augmented insulin/pSer473-Akt/pSer9-GSK-3β signaling, and lowered SCOP, pThr308-Akt/Akt and GLUT4 levels

C. Carlson, I. Sjaastad, G. Christensen, 2022, Frontiers in Cell and Developmental Biology.

Endothelin Release Associated with Splanchnic Ischemia is Abolished by Inhibition of Leukocyte-derived Proteases

E. Schlichting, G. Christensen, T. Lyberg, 1995 .

Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy

C. Carlson, I. Sjaastad, G. Christensen, 2022, Molecular Biology Reports.

Calcineurin-NFAT dynamics correspond to cardiac remodeling during aortic banding and debanding, mimicking aortic valve replacement

C. Carlson, I. Sjaastad, G. Christensen, 2022, Frontiers in Molecular Medicine.

Integrin α11β1 and syndecan-4 dual receptor ablation attenuates cardiac hypertrophy in the pressure overloaded heart.

I. Sjaastad, G. Christensen, H. Stenmark, 2022, American journal of physiology. Heart and circulatory physiology.

Plasma IL-18 and IL-18BP are altered differently in reverse remodeling following aortic valve replacement

J. Pepper, G. Christensen, T. Tønnessen, 2010, Scandinavian cardiovascular journal : SCJ.

Syndecans in heart fibrosis

G. Christensen, I. Lunde, K. Herum, 2016, Cell and Tissue Research.

Extreme altitude induces divergent mass reduction of right and left ventricle in mountain climbers

I. Sjaastad, G. Christensen, O. Skjønsberg, 2022, Physiological reports.

AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR

C. Carlson, D. Bers, I. Sjaastad, 2021, Circulation research.

Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle.

I. Sjaastad, S. Nygård, G. Christensen, 2012, Journal of applied physiology.

STIM1 R304W causes muscle degeneration and impaired platelet activation in mice.

D. Misceo, H. Westerblad, G. Christensen, 2018, Cell calcium.

A Dominant STIM1 Mutation Causes Stormorken Syndrome

D. Misceo, R. Lyle, A. Stray-Pedersen, 2014, Human mutation.

The Cardiac Syndecan-2 Interactome

C. Carlson, T. Nyman, G. Christensen, 2020, Frontiers in Cell and Developmental Biology.

Prognostic and diagnostic significance of mid-regional pro-atrial natriuretic peptide in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 Study

A. Høiseth, J. Brynildsen, G. Christensen, 2018, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

Endothelin-1 in the Human Myocardium and Circulating Plasma: Evaluation before, during and after Correction of Aortic Stenosis with Aortic Valve Replacement

G. Christensen, T. Tønnessen, T. Husebye, 2012, Cardiology.

Generation of a novel mouse strain with fibroblast-specific expression of Cre recombinase

G. Christensen, D. Gullberg, B. Eckes, 2020, Matrix biology plus.

Long-term levosimendan treatment improves systolic function and myocardial relaxation in mice with cardiomyocyte-specific disruption of the Serca2 gene.

G. Christensen, S. Golz, K. Andersson, 2013, Journal of applied physiology.

Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure

R. DeVita, R. Hajjar, R. Sanchez, 2015, Nature Communications.

Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene.

I. Sjaastad, K. Chien, O. Sejersted, 2009, Journal of molecular and cellular cardiology.

Circulating MicroRNA-210 Concentrations in Patients with Acute Heart Failure: Data from the Akershus Cardiac Examination 2 Study.

U. Wisløff, A. Høiseth, G. Christensen, 2021, Clinical chemistry.

Sweet, yet underappreciated: Proteoglycans and extracellular matrix remodeling in heart disease.

G. Christensen, Geir Christensen, Ida G Lunde, 2019, Matrix biology : journal of the International Society for Matrix Biology.

The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGFβ signalling in cardiac fibroblasts

G. Christensen, T. Tønnessen, S. Apte, 2021, Scientific Reports.

Diastolic dysfunction in alveolar hypoxia: a role for interleukin-18-mediated increase in protein phosphatase 2A.

K. Krobert, I. Sjaastad, K. Taskén, 2008, Cardiovascular research.

Alveolar hypoxia induces left ventricular diastolic dysfunction and reduces phosphorylation of phospholamban in mice.

K. Krobert, A. Svindland, I. Sjaastad, 2006, American journal of physiology. Heart and circulatory physiology.

The influence of heart failure co-morbidity on high-sensitivity troponin T levels in COPD exacerbation in a prospective cohort study: data from the Akershus cardiac examination (ACE) 2 study

A. Høiseth, J. Brynildsen, T. Hagve, 2016, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

Lack of pro-inflammatory cytokine mobilization predicts poor prognosis in patients with acute heart failure.

E. Pettersen, S. Nygård, A. Høiseth, 2013, Cytokine.

Increased cardiac IL-18 mRNA, pro-IL-18 and plasma IL-18 after myocardial infarction in the mouse; a potential role in cardiac dysfunction.

G. Christensen, T. Lyberg, T. Tønnessen, 2003, Cardiovascular research.

Lumican is increased in experimental and clinical heart failure, and its production by cardiac fibroblasts is induced by mechanical and proinflammatory stimuli

Biljana Skrbic, Ivar Sjaastad, I. Sjaastad, 2013, The FEBS journal.

Multiple cytokine biomarkers in heart failure

G. Christensen, T. Omland, M. Vistnes, 2010, Expert review of molecular diagnostics.

Daily administration of interleukin-18 causes myocardial dysfunction in healthy mice.

S. Djurovic, T. Strømme, G. Christensen, 2005, American journal of physiology. Heart and circulatory physiology.

Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy

G. Christensen, S. Aakhus, T. Ueland, 2017, Scientific Reports.

Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(alphaMHC-MerCreMer) mice.

I. Sjaastad, O. Sejersted, S. Nygård, 2010, American journal of physiology. Heart and circulatory physiology.

Glycosylated Chromogranin A in Heart Failure: Implications for Processing and Cardiomyocyte Calcium Homeostasis.

C. Carlson, I. Sjaastad, M. Stridsberg, 2017, Circulation. Heart failure.

Separate mechanisms cause anemia in ischemic vs. nonischemic murine heart failure.

P. Iversen, I. Sjaastad, O. Sejersted, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

The Homeostatic Chemokine CCL21 Predicts Mortality in Aortic Stenosis Patients and Modulates Left Ventricular Remodeling

I. Sjaastad, G. Christensen, S. Aakhus, 2014, PloS one.

Secretogranin II; a Protein Increased in the Myocardium and Circulation in Heart Failure with Cardioprotective Properties

I. Sjaastad, M. Stridsberg, G. Christensen, 2012, PloS one.

Echocardiographic parameters discriminating myocardial infarction with pulmonary congestion from myocardial infarction without congestion in the mouse.

I. Sjaastad, G. Christensen, A. Finsen, 2005, Journal of applied physiology.

Fibroblast growth factor 23 in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study.

A. Høiseth, J. Brynildsen, G. Christensen, 2017, Clinical biochemistry.

VI Scandinavian COPD Research SymposiumPublished with support from Boehringer Ingelheim

J. Kongerud, I. Sjaastad, Jing Gao, 2015, European Clinical Respiratory Journal.

Attenuated development of cardiac fibrosis in left ventricular pressure overload by SM16, an orally active inhibitor of ALK5.

I. Sjaastad, G. Christensen, T. Tønnessen, 2014, Journal of molecular and cellular cardiology.

A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice

I. Sjaastad, G. Christensen, J. M. Aronsen, 2018, Cardiovascular research.

Evaluation of a new fiber-optic pressure recording system for cardiovascular measurements in mice.

Arnfinn Ilebekk, T. Strømme, G. Christensen, 2003, American journal of physiology. Heart and circulatory physiology.

Prognostic Value of Circulating MicroRNA-210 Levels in Patients with Moderate to Severe Aortic Stenosis

U. Wisløff, T. Edvardsen, G. Christensen, 2014, PloS one.

Effects of Congestive Heart Failure on Ca2+ Handling in Skeletal Muscle During Fatigue

H. Westerblad, O. Sejersted, G. Christensen, 2006, Circulation research.

Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes.

I. Sjaastad, O. Sejersted, G. Christensen, 2010, Cardiovascular research.

The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy

G. Christensen, S. Aakhus, T. Lekva, 2017, Journal of Cardiovascular Translational Research.

The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling

Jan Magnus Aronsen, Ivar Sjaastad, I. Sjaastad, 2018, PloS one.

chapter 5 – Mouse Models of Human Cardiovascular Disease

J. Ross, K. Chien, G. Christensen, 2004 .

Sodium accumulation in SERCA knockout-induced heart failure.

S. Niederer, N. Smith, O. Sejersted, 2012, Biophysical journal.

Cardiomyocyte substructure reverts to an immature phenotype during heart failure

J. Hell, I. Sjaastad, G. Christensen, 2019, The Journal of physiology.

Lumican accumulates with fibrillar collagen in fibrosis in hypertrophic cardiomyopathy

I. Sjaastad, G. Christensen, T. Ueland, 2022, ESC heart failure.

IL‐18 neutralization during alveolar hypoxia improves left ventricular diastolic function in mice

I. Sjaastad, S. Nygård, G. Christensen, 2015, Acta physiologica.

Syndecans in heart fibrosis

G. Christensen, I. Lunde, K. Herum, 2016, Cell and Tissue Research.

Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension.

C. Carlson, I. Sjaastad, G. Christensen, 2019, American journal of physiology. Lung cellular and molecular physiology.

ADAMTSL3 knock-out mice develop cardiac dysfunction and dilatation with increased TGFβ signalling after pressure overload

Daniel R. Martin, S. Heymans, I. Sjaastad, 2022, Communications biology.

Differential regulation of extracellular matrix constituents in myocardial remodeling with and without heart failure following pressure overload.

C. Carlson, I. Sjaastad, S. Nygård, 2013, Matrix biology : journal of the International Society for Matrix Biology.

Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression

I. Sjaastad, S. Niederer, O. Sejersted, 2018, Cardiovascular research.

Sodium accumulation promotes diastolic dysfunction in end‐stage heart failure following Serca2 knockout

I. Sjaastad, O. Sejersted, G. Christensen, 2010, The Journal of physiology.

Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis

I. Sjaastad, P. A. Norseng, O. Sejersted, 2016, Cardiovascular research.

Synchrony of cardiomyocyte Ca(2+) release is controlled by T-tubule organization, SR Ca(2+) content, and ryanodine receptor Ca(2+) sensitivity.

I. Sjaastad, O. Sejersted, G. Christensen, 2013, Biophysical journal.

No rest for the weary: diastolic calcium homeostasis in the normal and failing myocardium.

I. Sjaastad, O. Sejersted, G. Christensen, 2012, Physiology.

Increased Levels of Eotaxin and MCP-1 in Juvenile Dermatomyositis Median 16.8 Years after Disease Onset; Associations with Disease Activity, Duration and Organ Damage

I. Sjaastad, G. Christensen, M. Vistnes, 2014, PloS one.

Syndecan-4 Is Essential for Development of Concentric Myocardial Hypertrophy via Stretch-Induced Activation of the Calcineurin-NFAT Pathway

S. Djurovic, C. Carlson, I. Sjaastad, 2011, PloS one.

Exercise training before cardiac-specific Serca2 disruption attenuates the decline in cardiac function in mice.

Ø. Ellingsen, I. Sjaastad, O. Sejersted, 2010, Journal of applied physiology.

Reduced level of serine(16) phosphorylated phospholamban in the failing rat myocardium: a major contributor to reduced SERCA2 activity.

I. Sjaastad, G. Christensen, T. Tønnessen, 2002, Cardiovascular research.

BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes

C. Carlson, T. Tuomainen, J. P. Morth, 2023, Circulation research.

Inflammation and Syndecan-4 Shedding from Cardiac Cells in Ischemic and Non-Ischemic Heart Disease

S. Heymans, G. Christensen, T. Tønnessen, 2023, Biomedicines.

Collagen isoform shift during the early phase of reverse left ventricular remodelling after relief of pressure overload.

I. Sjaastad, S. Nygård, G. Christensen, 2011, European heart journal.

Influence of glycosylation on diagnostic and prognostic accuracy of N-terminal pro-B-type natriuretic peptide in acute dyspnea: data from the Akershus Cardiac Examination 2 Study.

A. Høiseth, J. Brynildsen, T. Hagve, 2015, Clinical chemistry.

Identifying pathogenic processes by integrating microarray data with prior knowledge

Trond Reitan, Vegard Nygaard, Eivind Hovig, 2014, BMC Bioinformatics.

Beta-adrenergic stimulation maintains cardiac function in Serca2 knockout mice.

Nicolas P Smith, Sander Land, Steven A Niederer, 2013, Biophysical journal.

the Normal and Failing Myocardium No Rest for the Weary: Diastolic Calcium Homeostasis in

I. Sjaastad, O. Sejersted, G. Christensen, 2016 .

Bridging Integrator 1 (BIN1) Initiates T-Tubule Growth during Cardiac Development and Disease

I. Sjaastad, O. Sejersted, G. Christensen, 2015 .

Calcium release units in heart failure: that's about the size of it.

G. Christensen, F. Swift, 2012, Cardiovascular research.

The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP)

C. Carlson, I. Sjaastad, T. Nyman, 2019, The Journal of Biological Chemistry.

transcriptional changes and without cardiomyopathy in Tg(αMHC

I. Sjaastad, S. Nygård, G. Christensen, 2010 .

myocardial infarction without congestion in the mouse from myocardial infarction with pulmonary congestion Echocardiographic parameters discriminating

W. Linke, I. Sjaastad, G. Christensen, 2015 .

NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture.

P. Sætrom, P. Iversen, I. Sjaastad, 2017, Cell reports.

Inhibition of the extracellular enzyme A disintegrin and metalloprotease with thrombospondin motif 4 prevents cardiac fibrosis and dysfunction

C. Carlson, I. Sjaastad, G. Christensen, 2023, Cardiovascular research.

Biological variation of secretoneurin; a novel cardiovascular biomarker implicated in arrhythmogenesis.

G. Christensen, T. Omland, H. Røsjø, 2021, Clinical biochemistry.

Synchrony of cardiomyocyte Ca(2+) release is controlled by T-tubule organization, SR Ca(2+) content, and ryanodine receptor Ca(2+) sensitivity.

I. Sjaastad, O. Sejersted, G. Christensen, 2013, Biophysical journal.

Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan‐4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure‐overloaded heart

C. Carlson, I. Sjaastad, G. Christensen, 2013, The FEBS journal.

Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress.

C. Carlson, I. Sjaastad, G. Christensen, 2013, Journal of molecular and cellular cardiology.

A Dominant STIM1 Mutation Causes Stormorken Syndrome

D. Misceo, R. Lyle, A. Stray-Pedersen, 2014, Human mutation.

[Diagnostic accuracy for heart failure – data from the Akershus Cardiac Examination 2 Study].

S. Nygård, A. Høiseth, J. Brynildsen, 2015, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke.

Regulation of neuronal type genes in congestive heart failure rats

G. Christensen, G. Christensen, T. Tønnessen, 2006, Acta physiologica.

Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia

C. Carlson, I. Sjaastad, S. Lehnart, 2019, Circulation. Arrhythmia and electrophysiology.

Prominent Heart Organ-Level Performance Deficits in a Genetic Model of Targeted Severe and Progressive SERCA2 Deficiency

G. Christensen, K. Andersson, J. Metzger, 2013, PloS one.

Effect of endothelin antagonism on the production of cytokines in eosinophilic airway inflammation.

G. Christensen, F. Finsnes, O. Skjønsberg, 2001, American journal of physiology. Lung cellular and molecular physiology.

Calcium dynamics in the ventricular myocytes of SERCA2 knockout mice: A modeling study.

N P Smith, S A Niederer, S. Niederer, 2011, Biophysical journal.

The cardiokine secreted Frizzled‐related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure

L. Tavazzi, R. Latini, G. Christensen, 2014, Journal of internal medicine.

Fibroblast growth factor 23 in patients with acute dyspnea : data from the Akershus Cardiac Examination ( ACE ) 2 Study Running head : FGF 23 in acute dyspnea

A. Høiseth, J. Brynildsen, G. Christensen, 2018 .

In active juvenile dermatomyositis, elevated eotaxin and MCP-1 and cholesterol levels in the upper normal range are associated with cardiac dysfunction.

I. Sjaastad, G. Christensen, M. Vistnes, 2014, Rheumatology.

Leukaemia inhibitory factor alters expression of genes involved in rat cardiomyocyte energy metabolism.

G. Christensen, G. Christensen, K. Andersson, 2004, Acta physiologica Scandinavica.

Ca(2+) wave probability is determined by the balance between SERCA2-dependent Ca(2+) reuptake and threshold SR Ca(2+) content.

I. Sjaastad, O. Sejersted, G. Christensen, 2011, Cardiovascular research.

Separate mechanisms cause anemia in ischemic vs. nonischemic murine heart failure.

P. Iversen, I. Sjaastad, O. Sejersted, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

Temporal expression and spatial distribution of the proteoglycan versican during cardiac fibrosis development

I. Sjaastad, G. Christensen, M. Vistnes, 2023, Matrix Biology Plus.

Ca2+ Wave Development in Ventricular Cardiomyocytes from Mice with Inducible Knockout of SERCA2

I. Sjaastad, O. Sejersted, G. Christensen, 2009 .

A mouse model of reverse cardiac remodelling following banding‐debanding of the ascending aorta

I. Sjaastad, G. Christensen, G. Christensen, 2012, Acta physiologica.

Elevated levels of activin A in clinical and experimental pulmonary hypertension.

I. Sjaastad, G. Christensen, T. Ueland, 2009, Journal of applied physiology.

Identifying pathogenic processes by integrating microarray data with prior knowledge

E. Hovig, Vegard Nygaard, T. Clancy, 2014, BMC Bioinformatics.

IL-18 and IL-12 synergy induces matrix degrading enzymes in the lung

G. Christensen, O. Skjønsberg, E. Løberg, 2012, Experimental lung research.

Regulation of cardiomyocyte t-tubule structure by preload and afterload: Roles in cardiac compensation and decompensation.

I. Sjaastad, S. Nygård, G. Christensen, 2024, The Journal of physiology.