P. Pigeon

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Antimicrobial, antitumor and side effects assessment of a newly synthesized tamoxifen analogue.

G. Jaouen, Fatma Abdmouleh, Mehdi El Arbi, 2020, Current Topics in Medicinal Chemistry.

Organometallic analogues of tamoxifen: Effect of the amino side-chain replacement by a carbonyl ferrocenyl moiety in hydroxytamoxifen

A. Vessières, G. Jaouen, P. Pigeon, 2007 .

Selective estrogen receptor modulators in the ruthenocene series. Synthesis and biological behavior.

A. Vessières, G. Jaouen, P. Pigeon, 2005, Journal of medicinal chemistry.

Ferrocenyl catechols: synthesis, oxidation chemistry and anti-proliferative effects on MDA-MB-231 breast cancer cells.

A. Vessières, G. Jaouen, P. Pigeon, 2012, Dalton transactions.

Ferrocenyl flavonoid-induced morphological modifications of endothelial cells and cytotoxicity against B16 murine melanoma cells

A. Vessières, G. Jaouen, P. Pigeon, 2013 .

Mesenchymal content of fresh bone marrow: a proposed quality control method for cell therapy

N. Boiret-Dupré, P. Pigeon, M. Berger, 2007, British journal of haematology.

Synthesis, oxidation chemistry and cytotoxicity studies on ferrocene derivatives of diethylstilbestrol.

A. Vessières, G. Jaouen, P. Pigeon, 2009, Dalton transactions.

The inhibition of tyrosinase by some aryl butenes: A desired activity or a side effect to avoid

A. Gargouri, G. Jaouen, E. Ketata, 2017 .

Effect of the amino chain length and the transformation into citric acid salts of aryl-diphenyl-butenes and ferrocenyl-diphenyl-butenes bearing two dimethylaminoalkyl chains on their antimicrobial activities

G. Jaouen, Mehdi El Arbi, Karim Jellali, 2013, SpringerPlus.

Anticancer properties of lipid and poly(ε‐caprolactone) nanocapsules loaded with ferrocenyl‐tamoxifen derivatives

G. Jaouen, P. Pigeon, L. Sancey, 2018, The Journal of pharmacy and pharmacology.

Evaluation of bactericidal and fungicidal activity of ferrocenyl or phenyl derivatives in the diphenyl butene series

A. Vessières, G. Jaouen, Ahmed Rebai, 2011 .

Side-Chain Effects on the 1-(Bis-aryl-methylidene)-[3]ferrocenophane Skeleton: Antiproliferative Activity against TNBC Cancer Cells and Comparison with the Acyclic Ferrocifen Series

A. Vessières, G. Jaouen, P. Pigeon, 2017 .

Small Structural Differences between Two Ferrocenyl Diphenols Determine Large Discrepancies of Reactivity and Biological Effects

A. Vessières, G. Jaouen, R. Toillon, 2019, ChemMedChem.

Synthesis and antiproliferative evaluation of novel hydroxypropyl-ferrociphenol derivatives, resulting from the modification of hydroxyl groups

G. Jaouen, P. Pigeon, S. Top, 2017 .

The length of the bridging chain in ansa-metallocenes influences their antiproliferative activity against triple negative breast cancer cells (TNBC).

G. Jaouen, P. Pigeon, S. Top, 2016, Dalton transactions.

Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation.

D. Mansuy, A. Vessières, G. Jaouen, 2016, Angewandte Chemie.

Oxidative Metabolism of Ferrocene Analogues of Tamoxifen: Characterization and Antiproliferative Activities of the Metabolites

D. Mansuy, A. Vessières, G. Jaouen, 2015, ChemMedChem.

Evidence for targeting thioredoxin reductases with ferrocenyl quinone methides. A possible molecular basis for the antiproliferative effect of hydroxyferrocifens on cancer cells.

A. Vessières, G. Jaouen, P. Pigeon, 2014, Journal of medicinal chemistry.

Characterization of nonexpanded mesenchymal progenitor cells from normal adult human bone marrow.

P. Pigeon, M. Berger, S. Descamps, 2005, Experimental hematology.

Dose effect activity of ferrocifen-loaded lipid nanocapsules on a 9L-glioma model.

A. Vessières, G. Jaouen, P. Pigeon, 2009, International journal of pharmaceutics.

Normal human bone marrow CD34(+)CD133(+) cells contain primitive cells able to produce different categories of colony-forming unit megakaryocytes in vitro.

P. Pigeon, M. Berger, S. Charrier, 2002, Experimental hematology.

Alkylations en absence de solvant organique—3

A. Loupy, P. Pigeon, G. Bram, 1984 .

Polycyclic systems: Synthesis of isoindolo[2,1-b]pyrrolo[1,2-d] [2,4]benzodiazocine and isoindolo[1,2-d]pyrrolo[1,2-a][1,5]benzodiazocine

B. Decroix, P. Pigeon, M. Othman, 1999 .

Diisoindolothieno[2,4]diazepines via a diastereoselective N-acyliminium ion cyclization

B. Decroix, P. Pigeon, 1998 .

Intramolecular amidoalkylation cyclizations in synthesis of novel pyrrolo(or isoindolo)thieno[2]benzazepines

B. Decroix, P. Pigeon, A. Mamouni, 1997 .

Synthesis of dibenz[c,e]azepine and benzo[e]thieno[c]azepine via, N-acyliminium ion cyclization

B. Decroix, P. Pigeon, 1997 .

Lipid nanocapsules loaded with an organometallic tamoxifen derivative as a novel drug-carrier system for experimental malignant gliomas.

A. Vessières, G. Jaouen, J. Benoit, 2008, Journal of controlled release : official journal of the Controlled Release Society.

Measurement of imatinib uptake by flow cytometry

N. Boiret-Dupré, P. Pigeon, M. Berger, 2012, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Nanoparticles loaded with ferrocenyl tamoxifen derivatives for breast cancer treatment.

A. Vessières, G. Jaouen, P. Pigeon, 2008, International journal of pharmaceutics.

Selective Estrogen‐Receptor Modulators (SERMs) in the Cyclopentadienylrhenium Tricarbonyl Series: Synthesis and Biological Behaviour

A. Vessières, G. Jaouen, P. Pigeon, 2004, Chembiochem : a European journal of chemical biology.

Importance of Combining Advanced Particle Size Analysis Techniques To Characterize Cell-Penetrating Peptide–Ferrocifen Self-Assemblies

G. Jaouen, P. Pigeon, B. Calvignac, 2020 .

A new series of ferrocifen derivatives, bearing two aminoalkyl chains, with strong antiproliferative effects on breast cancer cells

A. Vessières, G. Jaouen, P. Pigeon, 2011 .

Succinimido–Ferrocidiphenol Complexed with Cyclodextrins Inhibits Glioblastoma Tumor Growth In Vitro and In Vivo without Noticeable Adverse Toxicity

G. Jaouen, P. Pigeon, A. Rhouma, 2022, Molecules.

The uptake of recombinant glucocerebrosidases by blood monocytes from type 1 Gaucher disease patients is variable

P. Pigeon, J. Stirnemann, N. Belmatoug, 2012, British journal of haematology.

Synthesis and structure-activity relationships of ferrocenyl tamoxifen derivatives with modified side chains.

A. Vessières, G. Jaouen, P. Pigeon, 2009, Chemistry.

Organometallic diphenols : The importance of the organometallic moiety on the expression of a cytotoxic effect on breast cancer cells

A. Vessières, G. Jaouen, P. Pigeon, 2007 .

Oxidative Sequence of a Ruthenocene-Based Anticancer Drug Candidate in a Basic Environment

G. Jaouen, P. Pigeon, S. Top, 2014 .

Synthesis, Cytotoxicity, and COMPARE Analysis of Ferrocene and [3]Ferrocenophane Tetrasubstituted Olefin Derivatives against Human Cancer Cells

A. Vessières, G. Jaouen, P. Pigeon, 2010, ChemMedChem.

Ferrocifen derivatives that induce senescence in cancer cells: selected examples.

R. Kiss, A. Vessières, G. Jaouen, 2014, Journal of inorganic biochemistry.

Ferrocifens and ferrocifenols as new potential weapons against breast cancer

A. Vessières, G. Jaouen, P. Pigeon, 2007 .

New fused lactones from indolizinediones via N-acyliminium ions

B. Decroix, P. Pigeon, M. Othman, 1998 .

Selective access to N-aryl or N-alkyl derivatives of isoindolo[2,1-b][2,4]benzo(or thieno)diazepines

B. Decroix, P. Pigeon, M. Othman, 1998 .

Alkylation of Diethyl Acetamidomalonate by Weak Electrophiles

A. Loupy, P. Pigeon, Jieping Zhu, 1995 .

Synthesis of 2-alkylcyclohexanones using solvent-free conditions and microwave technology

A. Loupy, P. Pigeon, M. Ramdani, 1993 .

Phase Transfer Catalysis without Solvent. Use of Alkyl Iodides

A. Loupy, E. Díez-Barra, P. Pigeon, 1989 .

Easy and Efficient Heterogeneous Nucleophilic Fluorination without Solvent

A. Loupy, P. Pigeon, G. Bram, 1988 .

A New Access to Isoindolo[2,1-b][2,4]benzodiazepines through an N-Acyliminium Ion - Amide Cyclization

B. Decroix, P. Pigeon, 1997 .

Antiparasitic and immunomodulatory activities of 1,1‐bis(4‐hydroxyphenyl)‐2‐phenyl‐but‐1‐ene and its protected and free 2‐ferrocenyl derivatives

G. Jaouen, P. Pigeon, R. Ribeiro‐dos‐Santos, 2009 .

Synthesis of benzo(or furo)[5,6]azepino[2,1-a]isoindolone derivatives: π-cyclisations of N-acyliminium ions

B. Decroix, P. Pigeon, A. Daïch, 1998 .

Benzothienoindolizidines via intramolecular aryl radical cyclization or palladium catalyzed cyclization

B. Decroix, P. Pigeon, 1996 .

A [3]ferrocenophane polyphenol showing a remarkable antiproliferative activity on breast and prostate cancer cell lines.

A. Vessières, G. Jaouen, P. Pigeon, 2009, Journal of medicinal chemistry.

Synthesis of long chain aromatic esters in a solvent-free procedure under microwaves

A. Loupy, P. Pigeon, M. Ramdani, 1996 .

Acyliminium ion cyclizations: Synthesis of thieno[2′,3′:3,4]pyrrolo[2,1-a] isoindolone and benzo[a]thieno[2,3(3,2 or 3,4)-g]indolizinones

B. Decroix, P. Pigeon, M. Othman, 1997 .

INTRODUCTION OF A CARBOXYMETHYLAMINO(OR OXY OR THIO) GROUP IN THE 3 POSITION OF 2-ARYL(OR ARYLMETHYL)ISOINDOL-1-ONES FROM ALPHA HYDROXYLACTAMS

B. Decroix, P. Pigeon, 1997 .

Tetracyclic systems: Synthesis of isoindolo[1,2-b]thieno-[2,3(3,2 or 3,4)-e][1,3]thiazocines and Isoindolo[2,1-a]thieno-[2,3(3,2 or 3,4)-f][1,4] and [1,5]diazocines

B. Decroix, P. Pigeon, 1997 .

The replacement of a phenol group by an aniline or acetanilide group enhances the cytotoxicity of 2-ferrocenyl-1,1-diphenyl-but-l-ene compounds against breast cancer cells

A. Vessières, G. Jaouen, P. Pigeon, 2009 .

Organometallic Antitumor Compounds: Ferrocifens as Precursors to Quinone Methides.

G. Jaouen, P. Pigeon, S. Top, 2015, Angewandte Chemie.

Synthesis and Antiproliferative Effects of [3]Ferrocenophane Transposition Products and Pinacols Obtained from McMurry Cross-Coupling Reactions

A. Vessières, G. Jaouen, P. Pigeon, 2012 .

Acyliminium ion-olefin cyclization leading to isoindolo[2,1-a]quinoline derivatives

B. Decroix, P. Pigeon, M. Othman, 1999 .

Selective cytotoxicity of arene tricarbonylchromium towards tumour cell lines

G. Jaouen, P. Pigeon, S. Top, 2018 .

A new generation of ferrociphenols leads to a great diversity of reactive metabolites, and exhibits remarkable antiproliferative properties

D. Mansuy, G. Jaouen, P. Pigeon, 2017, Chemical science.

ANTIMICROBIAL EFFECT OF FERROCENYL DIARYL BUTENES AGAINST OLIVE PLANTLET DISEASES

G. Jaouen, Ahmed Rebai, P. Pigeon, 2011 .

The influence of phenolic hydroxy substitution on the electron transfer and anti-cancer properties of compounds based on the 2-ferrocenyl-1-phenyl-but-1-ene motif.

A. Vessières, G. Jaouen, P. Pigeon, 2007, Dalton transactions.

Thieno[2′,3′:5,6]azepino[2,1- a ]isoindolones from hydroxylactam-alcohols via N -acyliminium ion olefin cyclization

B. Decroix, P. Pigeon, M. Othman, 2001 .

Novel Approach to Isoindolo[2,1-a]quinolines

B. Decroix, P. Pigeon, 1998 .

A New Access to Isoindolo(2,1-b)(2,4)benzodiazepines Through an N- Acyliminium Ion-Amide Cyclization.

B. Decroix, P. Pigeon, 1997 .

Modification of the estrogenic properties of diphenols by the incorporation of ferrocene. Generation of antiproliferative effects in vitro.

A. Vessières, G. Jaouen, P. Pigeon, 2005, Journal of medicinal chemistry.

Solid-Liquid Phase Transfer Catalysis Without Solvent: Further Improvement in SNAr Reactions

A. Loupy, P. Pigeon, J. Sansoulet, 1990 .

ALKYLATIONS IN THE ABSENCE OF AN ORGANIC SOLVENT. EFFECTS OF THE ADDITION OF MINERAL OXIDES AND AMMONIUM SALTS. II. EASY SYNTHESIS OF ESTERS BY ALKYLATION N OF THE ACETATE ANION UNDER SOFT, ECONOMICAL CONDITIONS

A. Loupy, P. Pigeon, J. Sansoulet, 1983 .

ALKYLATIONS IN THE ABSENCE OF AN ORGANIC SOLVENT. EFFECTS OF THE ADDITION OF MINERAL OXIDES AND AMMONIUM SALTS. I. N-ALKYLATION OF INDOLE IN A BASIC MEDIUM

A. Loupy, P. Pigeon, J. Sansoulet, 1983 .

Comparative toxicity of [3]ferrocenophane and ferrocene moieties on breast cancer cells

A. Vessières, G. Jaouen, P. Pigeon, 2010 .

Molecular Mechanism of Action of 2‐Ferrocenyl‐1,1‐diphenylbut‐1‐ene on HL‐60 Leukemia Cells

G. Jaouen, P. Pigeon, E. Hillard, 2014, ChemMedChem.

Phthalimido-ferrocidiphenol cyclodextrin complexes: Characterization and anticancer activity.

G. Jaouen, P. Pigeon, A. Rhouma, 2015, International journal of pharmaceutics.

Tamoxifen-like metallocifens target the thioredoxin system determining mitochondrial impairment leading to apoptosis in Jurkat cells.

A. Vessières, G. Jaouen, P. Pigeon, 2017, Metallomics : integrated biometal science.

First anti-oestrogen in the cyclopentadienyl rhenium tricarbonyl series. Synthesis and study of antiproliferative effects

G. Leclercq, A. Vessières, G. Jaouen, 2001 .

Ferrocenophane polyphenol showing a remarkable antiproliferative activity on breast and prostate cancer cell lines

A. Vessières, G. Jaouen, P. Pigeon, 2019 .

Antiplasmodial activity of iron(II) and ruthenium(II) organometallic complexes against Plasmodium falciparum blood parasites

G. Jaouen, P. Pigeon, S. Top, 2015, Memorias do Instituto Oswaldo Cruz.

Facile synthesis and strong antiproliferative activity of disubstituted diphenylmethylidenyl-[3]ferrocenophanes on breast and prostate cancer cell lines

A. Vessières, G. Jaouen, P. Pigeon, 2010 .

Antibacterial properties and mode of action of new triaryl butene citrate compounds.

G. Jaouen, Mehdi El Arbi, Karim Jellali, 2014, European journal of medicinal chemistry.

Atypical McMurry Cross-Coupling Reactions Leading to a New Series of Potent Antiproliferative Compounds Bearing the Key [Ferrocenyl-Ene-Phenol] Motif

G. Jaouen, P. Pigeon, S. Top, 2014, Molecules.

Biological evaluation of twenty-eight ferrocenyl tetrasubstituted olefins: cancer cell growth inhibition, ROS production and hemolytic activity.

G. Jaouen, P. Pigeon, E. Hillard, 2011, European journal of medicinal chemistry.

A New Series of Succinimido-ferrociphenols and Related Heterocyclic Species Induce Strong Antiproliferative Effects, Especially against Ovarian Cancer Cells Resistant to Cisplatin.

G. Jaouen, J. Bignon, P. Pigeon, 2017, Journal of medicinal chemistry.

A New Solvent-Free Procedure Using Microwave Technology as an Alternative to the Krapcho Reaction.

A. Loupy, P. Pigeon, M. Ramdani, 1993 .

Physicochemical Characterization of Ferrocifen Lipid Nanocapsules: Customized Drug Delivery Systems Guided by the Molecular Structure.

A. Vessières, G. Jaouen, P. Pigeon, 2023, Langmuir : the ACS journal of surfaces and colloids.

Ferrocifen stealth LNCs and conventional chemotherapy: a promising combination against multidrug-resistant ovarian adenocarcinoma.

G. Jaouen, P. Pigeon, C. Passirani, 2022, International journal of pharmaceutics.

α-Hydroxylactams as Efficient Entries to Diversely Functionalized Ferrociphenols: Synthesis and Antiproliferative Activity Studies

G. Jaouen, P. Pigeon, M. Salmain, 2022, Molecules.

Diversity-oriented synthesis and bioactivity evaluation of N-substituted ferrocifen compounds as novel antiproliferative agents against TNBC cancer cells.

G. Jaouen, P. Pigeon, P. Dansette, 2022, European journal of medicinal chemistry.

Heterogeneity of Response to Iron-Based Metallodrugs in Glioblastoma Is Associated with Differences in Chemical Structures and Driven by FAS Expression Dynamics and Transcriptomic Subtypes

M. Sanson, A. Idbaih, A. Vessières, 2021, International journal of molecular sciences.

Atypical Lone Pair-π Interaction with Quinone Methides in a Series of Imido-Ferrociphenol Anticancer Drug Candidates.

I. Ciofini, G. Jaouen, P. Pigeon, 2019, Angewandte Chemie.

Atypical Lone Pair–π Interaction with Quinone Methides in a Series of Imido‐Ferrociphenol Anticancer Drug Candidates

I. Ciofini, G. Jaouen, P. Pigeon, 2019, Angewandte Chemie.

The in vivo performance of ferrocenyl tamoxifen lipid nanocapsules in xenografted triple negative breast cancer.

A. Vessières, G. Jaouen, R. Toillon, 2013, Biomaterials.

Quinoxalines,Bezodiazepines and Bezodiazocines Fused to Pyrrole and Isoindole via N-Acyliminium Ion Aromatic Cyclization

B. Decroix, P. Pigeon, A. Daïch, 2000 .

Study of a 1,6-hydride shift in an open chain of hydroxylactam-triarylcarbinols

B. Decroix, P. Pigeon, S. Marchalin, 2001 .

Selective Access to N‐Aryl or N‐Alkyl Derivatives of Isoindolo[2,1‐b][2,4]benzo(or thieno)diazepines.

B. Decroix, P. Pigeon, M. Othman, 1998 .

Synthesis of thieno[2′,3′(3′,4′ or 3′,2′):5,6]azepino[2,1-a]isoindolediones from N-Thienyl-2(3)-ylmethylphthalimides

B. Decroix, P. Pigeon, 1996 .

Ferrocenyl compounds possessing protected phenol and thiophenol groups: Synthesis, X-ray structure, and in vitro biological effects against breast cancer

A. Vessières, G. Jaouen, P. Pigeon, 2008 .

CD34+CDw90(Thy-1)+ subset colocated with mesenchymal progenitors in human normal bone marrow hematon units is enriched in colony-forming unit megakaryocytes and long-term culture-initiating cells.

P. Pigeon, M. Berger, S. Boisgard, 2003, Experimental hematology.

Immunoreactive fibroblast growth factor (FGF) in rat tissues: molecular weight forms and the effects of hypophysectomy.

P. Pigeon, A. Baird, P. Pigeon, 1985, Biochemical and biophysical research communications.

Enhanced and preferential internalization of lipid nanocapsules into human glioblastoma cells: effect of a surface-functionalizing NFL peptide.

G. Jaouen, P. Pigeon, L. Lemaire, 2018, Nanoscale.

Selection of a Suitable Disc Bioassay for the Screening of Anti-Tumor Molecules

Mehdi El Arbi, P. Pigeon, S. Top, 2013, International journal of biomedical science : IJBS.

Role of aromatic substituents on the antiproliferative effects of diphenyl ferrocenyl butene compounds.

A. Vessières, G. Jaouen, P. Pigeon, 2009, Dalton transactions.

Aryl Butenes Active against K562 Cells and Lacking Tyrosinase Inhibitory Activity as New Leads in the Treatment of Leukemia.

A. Gargouri, G. Jaouen, E. Ketata, 2017, Mini reviews in medicinal chemistry.

Efficacy of a novel ferrocenyl diaryl butene citrate compound as a biocide for preventing healthcare-associated infections

G. Jaouen, P. Pigeon, S. Top, 2016 .

Electrochemical attachment of a conjugated amino-ferrocifen complex onto carbon and metal surfaces

G. Jaouen, P. Pigeon, C. Amatore, 2008 .

Enzymatic oxidation of ansa-ferrocifen leads to strong and selective thioredoxin reductase inhibition in vitro.

I. Ciofini, A. Vessières, G. Jaouen, 2016, Journal of inorganic biochemistry.

The importance to combine advanced particle size analysis techniques to characterize cell penetrating peptide-ferrocifen self-assemblies.

F. Franconi, G. Jaouen, P. Pigeon, 2019, The journal of physical chemistry letters.

Lipid nanocapsules loaded with an organometallic tamoxifen derivative as a novel drug-carrier system for experimental malignant gliomas

A. Vessières, G. Jaouen, J. Benoit, 2020 .

Inhibition of cathepsin B by ferrocenyl indenes highlights a new pharmacological facet of ferrocifens

Isabelle Navizet, A. Vessières, G. Jaouen, 2022, European Journal of Inorganic Chemistry.

Lipid nanocapsules loaded with an organometallic tamoxifen derivative as a novel drug-carrier system for experimental malignant gliomas.

A. Vessières, G. Jaouen, J. Benoit, 2008, Journal of controlled release : official journal of the Controlled Release Society.

A short route to cyclopentadienyltricarbonylrhenium substituted derivatives

G. Jaouen, P. Pigeon, S. Top, 2003 .

Intramolecular Addition of a Hydroxyl to an N-Acyliminium System. Application to the Synthesis of Isoindolo[2,1-a][3,1]benzoxazine and Isoindolo[1,2-c][2,4]benzoxazepine Derivatives

B. Decroix, P. Pigeon, S. Marchalin, 2002 .

Enhanced and preferential internalization of lipid nanocapsules into human glioblastoma cells: effect of a surface-functionalizing NFL peptide.

G. Jaouen, P. Pigeon, L. Lemaire, 2018, Nanoscale.

Oxidative Metabolism of Ferrocene Analogues of Tamoxifen: Characterization and Antiproliferative Activities of the Metabolites

D. Mansuy, A. Vessières, G. Jaouen, 2015, ChemMedChem.

Anticancer properties of lipid and poly( ε -caprolactone) nanocapsules loaded with 1 ferrocenyl tamoxifen derivatives

P. Pigeon, Sonia Aroui, M. Waard, 2018 .

Phthalimido-ferrocidiphenol cyclodextrin complexes: Characterization and anticancer activity.

G. Jaouen, P. Pigeon, A. Rhouma, 2015, International journal of pharmaceutics.

Deciphering the Diversified Metabolic Behavior of Hydroxyalkyl Ferrocidiphenols as Anticancer Complexes

Shuang Yang, P. Pigeon, M. McGlinchey, 2023, Journal of Medicinal Chemistry.

Unravelling the Role of Uncommon Hydrogen Bonds in Cyclodextrin Ferrociphenol Supramolecular Complexes: A Computational Modelling and Experimental Study

G. Jaouen, P. Pigeon, M. McGlinchey, 2023, International journal of molecular sciences.