S. Top

发表

Antimicrobial, antitumor and side effects assessment of a newly synthesized tamoxifen analogue.

G. Jaouen, Fatma Abdmouleh, Mehdi El Arbi, 2020, Current Topics in Medicinal Chemistry.

Synthesis and antiproliferative activity of (Z + E)‐1‐[4‐(2‐(cyclopentadienyltricarbonylmanganese)‐2‐oxo‐ethoxy)phenyl]‐1,2‐di(p‐hydroxyphenyl)‐but‐1‐ene against breast cancer cells

G. Jaouen, S. Top, Tesnim Dallagi, 2013 .

Organometallic analogues of tamoxifen: Effect of the amino side-chain replacement by a carbonyl ferrocenyl moiety in hydroxytamoxifen

A. Vessières, G. Jaouen, P. Pigeon, 2007 .

Selective estrogen receptor modulators in the ruthenocene series. Synthesis and biological behavior.

A. Vessières, G. Jaouen, P. Pigeon, 2005, Journal of medicinal chemistry.

Synthesis, biochemical properties and molecular modelling studies of organometallic specific estrogen receptor modulators (SERMs), the ferrocifens and hydroxyferrocifens: evidence for an antiproliferative effect of hydroxyferrocifens on both hormone-dependent and hormone-independent breast cancer ce

G. Leclercq, A. Vessières, G. Jaouen, 2003, Chemistry.

Ferrocenyl catechols: synthesis, oxidation chemistry and anti-proliferative effects on MDA-MB-231 breast cancer cells.

A. Vessières, G. Jaouen, P. Pigeon, 2012, Dalton transactions.

Reactivity and reaction pathways of electrochemically generated 17-electron tricarbonyl steroid chromium cations

A. Bond, G. Jaouen, S. Top, 1990 .

Oxidation of Cymantrene Analogues of Ferrocifen: Electrochemical, Spectroscopic, and Computational Studies of the Parent Complex 1,1′-Diphenyl-2-cymantrenylbutene

M. Baik, G. Jaouen, S. Top, 2018, Organometallics.

Synthesis and biological activity of ferrocenyl derivatives of the non-steroidal antiandrogens flutamide and bicalutamide

A. Vessières, G. Jaouen, S. Top, 2011 .

Synthesis, oxidation chemistry and cytotoxicity studies on ferrocene derivatives of diethylstilbestrol.

A. Vessières, G. Jaouen, P. Pigeon, 2009, Dalton transactions.

The inhibition of tyrosinase by some aryl butenes: A desired activity or a side effect to avoid

A. Gargouri, G. Jaouen, E. Ketata, 2017 .

Effect of the amino chain length and the transformation into citric acid salts of aryl-diphenyl-butenes and ferrocenyl-diphenyl-butenes bearing two dimethylaminoalkyl chains on their antimicrobial activities

G. Jaouen, Mehdi El Arbi, Karim Jellali, 2013, SpringerPlus.

Ferrocenyl quinone methides as strong antiproliferative agents: formation by metabolic and chemical oxidation of ferrocenyl phenols.

D. Mansuy, A. Vessières, G. Jaouen, 2009, Angewandte Chemie.

Approach to ferrocenyl-podophyllotoxin analogs and their evaluation as anti-tumor agents

A. Vessières, G. Jaouen, S. Top, 2017 .

Evaluation of bactericidal and fungicidal activity of ferrocenyl or phenyl derivatives in the diphenyl butene series

A. Vessières, G. Jaouen, Ahmed Rebai, 2011 .

The Biological Target Potential of Organometallic Steroids

G. Jaouen, S. Top, M. McGlinchey, 2014 .

Synchrotron Radiation X-Ray Fluorescence Nanoimaging Reveal the Intracellular Localization of Potent Anticancer Drug Osmocenyl-Tamoxifen Derivative

P. Cloetens, G. Jaouen, S. Top, 2018, Microscopy and Microanalysis.

Side-Chain Effects on the 1-(Bis-aryl-methylidene)-[3]ferrocenophane Skeleton: Antiproliferative Activity against TNBC Cancer Cells and Comparison with the Acyclic Ferrocifen Series

A. Vessières, G. Jaouen, P. Pigeon, 2017 .

Synthesis, Characterization, and Antiproliferative Activities of Novel Ferrocenophanic Suberamides against Human Triple-Negative MDA-MB-231 and Hormone-Dependent MCF-7 Breast Cancer Cells

G. Jaouen, S. Top, C. Amatore, 2013 .

New mechanistic insights into osmium-based tamoxifen derivatives

A. Vessières, G. Jaouen, S. Top, 2019, Electrochimica Acta.

Small Structural Differences between Two Ferrocenyl Diphenols Determine Large Discrepancies of Reactivity and Biological Effects

A. Vessières, G. Jaouen, R. Toillon, 2019, ChemMedChem.

Synthesis and antiproliferative evaluation of novel hydroxypropyl-ferrociphenol derivatives, resulting from the modification of hydroxyl groups

G. Jaouen, P. Pigeon, S. Top, 2017 .

The length of the bridging chain in ansa-metallocenes influences their antiproliferative activity against triple negative breast cancer cells (TNBC).

G. Jaouen, P. Pigeon, S. Top, 2016, Dalton transactions.

Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation.

D. Mansuy, A. Vessières, G. Jaouen, 2016, Angewandte Chemie.

Ferrocifen type anti cancer drugs.

A. Vessières, G. Jaouen, S. Top, 2015, Chemical Society reviews.

Oxidative Metabolism of Ferrocene Analogues of Tamoxifen: Characterization and Antiproliferative Activities of the Metabolites

D. Mansuy, A. Vessières, G. Jaouen, 2015, ChemMedChem.

Synthesis, Characterization, and Biological Properties of Osmium-Based Tamoxifen Derivatives - Comparison with Their Homologues in the Iron and Ruthenium Series: Osmium-Based Tamoxifen Derivatives

A. Vessières, G. Jaouen, S. Top, 2015 .

Evidence for targeting thioredoxin reductases with ferrocenyl quinone methides. A possible molecular basis for the antiproliferative effect of hydroxyferrocifens on cancer cells.

A. Vessières, G. Jaouen, P. Pigeon, 2014, Journal of medicinal chemistry.

Synthesis and Structure Activity Relationship of Organometallic Steroidal Androgen Derivatives

J. Marrot, A. Vessières, G. Jaouen, 2009 .

The first organometallic selective estrogen receptor modulators (SERMs) and their relevance to breast cancer.

G. Leclercq, A. Vessières, G. Jaouen, 2004, Current medicinal chemistry.

The Ferrocifen Family as Potent and Selective Antitumor Compounds: Mechanisms of Action

G. Jaouen, S. Top, 2013 .

Labeling of proteins by organometallic complexes of rhenium. (I). Synthesis and biological activity of the conjugates.

G. Jaouen, S. Top, M. Salmain, 1993, Bioconjugate chemistry.

New and efficient routes to biomolecules substituted with cyclopentadienyltricarbonylrhenium and -technetium derivatives.

G. Jaouen, S. Top, M. Salmain, 2001, Chemistry.

Microbial resolution of organometallic planar chirality. Enantioselective reduction of orto- and meta-substituted tricarbonylchromium benzaldehydes by bakers' yeast

S. Top, C. Baldoli, S. Maiorana, 1991 .

Synthesis and characterization of new ferrocenyl compounds with different alkyl chain lengths and functional groups to target breast cancer cells

G. Jaouen, S. Top, José de Jesús Cázares-Marinero, 2014 .

Efficient new constructs against triple negative breast cancer cells: synthesis and preliminary biological study of ferrocifen-SAHA hybrids and related species.

A. Vessières, G. Jaouen, S. Top, 2013, Dalton transactions.

A DFT study on the mechanism of a novel, regioselective, intramolecular N-pi rearrangement of cis and trans-eta1-N-Cp*Rh-hydroxytamoxifen complexes to their eta6 derivatives; potential breast cancer pharmaceuticals, and fluorescent probes.

S. Top, Jan M. L. Martin, I. Efremenko, 2009, Dalton transactions.

Pressure-tuning infrared and solution Raman spectroscopic studies of 17β-estradiol and several A-ring and 17α-ethynylestradiol derivatives

G. Jaouen, S. Top, I. Butler, 1995 .

Ferrocifens labelled with an infrared rhenium tricarbonyl tag: synthesis, antiproliferative activity, quantification and nano IR mapping in cancer cells.

A. Vessières, G. Jaouen, S. Top, 2018, Dalton transactions.

Nanoparticles loaded with ferrocenyl tamoxifen derivatives for breast cancer treatment.

A. Vessières, G. Jaouen, P. Pigeon, 2008, International journal of pharmaceutics.

Selective Estrogen‐Receptor Modulators (SERMs) in the Cyclopentadienylrhenium Tricarbonyl Series: Synthesis and Biological Behaviour

A. Vessières, G. Jaouen, P. Pigeon, 2004, Chembiochem : a European journal of chemical biology.

Studies on organometallic selective estrogen receptor modulators. (SERMs) Dual activity in the hydroxy-ferrocifen series

G. Leclercq, A. Vessières, G. Jaouen, 2001 .

Determination of citrate in urine by simple direct photometry.

S. Top, D. Yücel, 1987, Clinical chemistry.

A new series of ferrocifen derivatives, bearing two aminoalkyl chains, with strong antiproliferative effects on breast cancer cells

A. Vessières, G. Jaouen, P. Pigeon, 2011 .

Ferrocenyl hydroxytamoxifen: a prototype for a new range of oestradiol receptor site-directed cytotoxics

A. Vessières, G. Jaouen, S. Top, 1996 .

Synthesis and structure-activity relationships of ferrocenyl tamoxifen derivatives with modified side chains.

A. Vessières, G. Jaouen, P. Pigeon, 2009, Chemistry.

Organometallic diphenols : The importance of the organometallic moiety on the expression of a cytotoxic effect on breast cancer cells

A. Vessières, G. Jaouen, P. Pigeon, 2007 .

The Presence of a Ferrocenyl Unit on an Estrogenic Molecule is Not Always Sufficient to Generate in vitro Cytotoxicity

Jan-Martin Heldt, A. Vessières, G. Jaouen, 2006, ChemMedChem.

Oxidative Sequence of a Ruthenocene-Based Anticancer Drug Candidate in a Basic Environment

G. Jaouen, P. Pigeon, S. Top, 2014 .

Synthesis, Cytotoxicity, and COMPARE Analysis of Ferrocene and [3]Ferrocenophane Tetrasubstituted Olefin Derivatives against Human Cancer Cells

A. Vessières, G. Jaouen, P. Pigeon, 2010, ChemMedChem.

Ferrocifen derivatives that induce senescence in cancer cells: selected examples.

R. Kiss, A. Vessières, G. Jaouen, 2014, Journal of inorganic biochemistry.

New paradigms for synthetic pathways inspired by bioorganometallic chemistry

A. Vessières, G. Jaouen, S. Top, 2000 .

Ferrocifens and ferrocifenols as new potential weapons against breast cancer

A. Vessières, G. Jaouen, P. Pigeon, 2007 .

FACILE ROUTE TO FERROCIFEN, 1-4-(2-DIMETHYLAMINOETHOXY)-1-(PHENYL-2-FERROCENYL-BUT-1-ENE), FIRST ORGANOMETALLIC ANALOGUE OF TAMOXIFEN, BY THE MCMURRY REACTION

G. Jaouen, S. Top, J. Vaissermann, 1997 .

The replacement of a phenol group by an aniline or acetanilide group enhances the cytotoxicity of 2-ferrocenyl-1,1-diphenyl-but-l-ene compounds against breast cancer cells

A. Vessières, G. Jaouen, P. Pigeon, 2009 .

Organometallic Antitumor Compounds: Ferrocifens as Precursors to Quinone Methides.

G. Jaouen, P. Pigeon, S. Top, 2015, Angewandte Chemie.

N-Alkylation of nitriles using chromium tricarbonyl complexes of benzyl alcohol and its derivatives: new perspectives for the Ritter reaction

G. Jaouen, S. Top, 1981 .

Synthesis and Antiproliferative Effects of [3]Ferrocenophane Transposition Products and Pinacols Obtained from McMurry Cross-Coupling Reactions

A. Vessières, G. Jaouen, P. Pigeon, 2012 .

Enantioselective microbial reduction of planar chiral organometallics of synthetic interest

G. Jaouen, S. Top, C. Baldoli, 1988 .

Formation de liaison C_C par couplage rducteur d'ions carbniums arne chrome tricarbonyle

S. Top, 1987 .

Synthesis of ethyl phenylpyruvate and related compounds using chromium tricarbonyl complexes

G. Jaouen, S. Top, B. Caro, 1984 .

Analyse structurale du phenyl pyruvate d'ethyle obtenu sous forme enolique par activation benzylique a l'aide de l'entite Cr(CO)3

G. Jaouen, S. Top, J. Saillard, 1984 .

Regiospecific and stereospecific functionalization of benzylic sites by tricarbonylchromium arene complexation

G. Jaouen, S. Top, D. Couturier, 1984 .

Stereospecific 6-alkylation of oestradiol derivatives via Cr(CO)3 complexes

A. Vessières, G. Jaouen, S. Top, 1984 .

Substituent effects in benzylic functionalization of arene(tricarbonyl) chromium complexes

G. Jaouen, S. Top, D. Couturier, 1984 .

Asymmetric induction via co-ordination to Cr(CO)3; nucleophilic attack on acyclic carbenium ions

G. Jaouen, S. Top, M. McGlinchey, 1980 .

N-alkylation of nitriles with tricarbonylchromium complexes of benzyl and related alcohols as synthetic intermediates. Further development of the Ritter reactions

G. Jaouen, S. Top, 1979 .

Stereoselective nucleophilic attacks on carbenium ions generated from (1-indanol)- and (1-tetralol)Cr(CO)3 as synthetic intermediates.

G. Jaouen, S. Top, A. Meyer, 1979 .

Selective cytotoxicity of arene tricarbonylchromium towards tumour cell lines

G. Jaouen, P. Pigeon, S. Top, 2018 .

Chromium tricarbonyl complexes of estradiol derivatives: differentiation of .alpha.- and .beta.-diastereoisomers using 1- and 2-dimensional NMR spectroscopy at 500 MHz

A. Vessières, G. Jaouen, S. Top, 1985 .

A new generation of ferrociphenols leads to a great diversity of reactive metabolites, and exhibits remarkable antiproliferative properties

D. Mansuy, G. Jaouen, P. Pigeon, 2017, Chemical science.

Modification of the Cp′ ring in the ferrocifen precursor and its influence on the recognition by the estrogen receptor

A. Vessières, G. Jaouen, S. Top, 2003 .

ANTIMICROBIAL EFFECT OF FERROCENYL DIARYL BUTENES AGAINST OLIVE PLANTLET DISEASES

G. Jaouen, Ahmed Rebai, P. Pigeon, 2011 .

Metal complex SERMs (selective oestrogen receptor modulators). The influence of different metal units on breast cancer cell antiproliferative effects.

A. Vessières, G. Jaouen, S. Top, 2006, Dalton transactions.

Metal carbonyl fragments as a new class of markers in molecular biology

A. Vessières, G. Jaouen, S. Top, 1985 .

Synthesis and structure-activity relationships of the first ferrocenyl-aryl-hydantoin derivatives of the nonsteroidal antiandrogen nilutamide.

A. Vessières, G. Jaouen, S. Top, 2008, Journal of medicinal chemistry.

A Novel and Mild Metal-Exchange Reaction in the Organometallic Cyclopentadienyl Series: 1,1‘-Diaryl 2-Cymantrenyl 1-Butene as an Example

G. Jaouen, S. Top, and El Bachir Kaloun, 2000 .

Rhenium Carbonyl Complexes of .beta.-Estradiol Derivatives with High Affinity for the Estradiol Receptor: An Approach to Selective Organometallic Radiopharmaceuticals

D. Hughes, A. Vessières, G. Jaouen, 1995 .

Modification of the estrogenic properties of diphenols by the incorporation of ferrocene. Generation of antiproliferative effects in vitro.

A. Vessières, G. Jaouen, P. Pigeon, 2005, Journal of medicinal chemistry.

The first organometallic antioestrogens and their antiproliferative effects

G. Leclercq, A. Vessières, G. Jaouen, 2000 .

Problems de stereochimie dynamique en serie du titanocene : II. Stereochimie dynamique de reactions déchange de ligands σ-lies

C. Lecomte, S. Top, J. Besancon, 1977 .

Transition-metal carbonyl complexes in progesterone receptor assay

G. Teutsch, A. Vessières, G. Jaouen, 1988 .

Isolation of fac-[Re(CO)3(HMPA)3][BF4]. Structural characterization of a key cationic intermediate in the exchange reaction between [Re(CO)6][BF4] and acetylferrocene. Implications in radiopharmaceutical chemistry

G. Jaouen, S. Top, R. Welter, 2004 .

Cyclopentadienyl transfer reaction: thermal reaction between Re2(CO)10 and a series of cyclopentadienyl transition metal complexes

G. Jaouen, S. Top, C. Lescop, 2000 .

Synthese directe de phenylpyruvates chrome tricarbonyle. Influences de la substitution sur la nature cetonique ou enolique des produits isoles, et du groupement Cr(CO)3 sur l'equilibre tautomere

G. Jaouen, S. Top, Jean-Yves Saillard, 1988 .

Protonation of chromium tricarbonyl complexes of triphenylsilanol and triphenylcarbinol: synthetic, x-ray crystallographic, and NMR study of (Ph3SiOH)[Cr(CO)3]n (n = 1-3) and of (Ph3COH)Cr(CO)3

K. Malisza, G. Jaouen, S. Top, 1993 .

Rotational barriers in diphenylmethyl anions stabilized by trimethylsilyl and tricarbonylchromium(0) moieties

G. Jaouen, S. Top, B. Sayer, 1983 .

First attachment of the stable organometallic moiety 〚Re(CO)3(η5-C5H4–C≡C–)〛 at position 11ß of oestradiol. Biochemical behaviour of the complex

G. Leclercq, A. Vessières, G. Jaouen, 2001 .

A fast route to the potential biological reagent (η5-C5H4COOH)Re(CO)3 from [NH4] [ReO4]

G. Jaouen, S. Top, P. Morel, 1999 .

A Carbon-13 NMR Spectroscopic Study of a Cr(CO)3-Stabilised Benzyl Anion

G. Jaouen, S. Top, M. McGlinchey, 1980 .

Reactions of eq,eq-Re2(CO)8(MeCN)2 with phenylacetylene and α-ethynylestradiol. A new synthesis of acetylide complexes

G. Jaouen, S. Top, J. Vaissermann, 1991 .

Synthesis and receptor binding of polynuclear organometallic estradiol derivatives.

A. Vessières, G. Jaouen, S. Top, 1988, Journal of steroid biochemistry.

The [Re(CO)6]+ Cation as a Ligand‐Transfer Reagent with Ferrocene Derivatives

G. Jaouen, S. Top, S. Masi, 2002 .

Synthesis of 17?-ruthenocenyl-17?-oestradiol and its potential as a radiopharmaceutical agent

A. Vessières, G. Jaouen, S. Top, 1997 .

Syntheses and affinities of novel organometallic-labeled estradiol derivatives: a structure-affinity relationship.

A. Vessières, G. Jaouen, S. Top, 1992, Journal of medicinal chemistry.

Estradiols Modified by Metal Carbonyl Clusters as Suicide Substrates for the Study of Receptor Proteins: Application to the Estradiol Receptor

D. Osella, A. Vessières, G. Jaouen, 1992 .

Organometallic estrogens: synthesis, interaction with lamb uterine estrogen receptor, and detection by infrared spectroscopy.

A. Vessières, G. Jaouen, S. Top, 1988, Biochemistry.

Organometallic cyclic polyphenols derived from 1,2-(alpha-keto tri or tetra methylene) ferrocene show strong antiproliferative activity on hormone-independent breast cancer cells.

A. Vessières, G. Jaouen, S. Top, 2010, Dalton transactions.

Comparative toxicity of [3]ferrocenophane and ferrocene moieties on breast cancer cells

A. Vessières, G. Jaouen, P. Pigeon, 2010 .

Tamoxifen-like metallocifens target the thioredoxin system determining mitochondrial impairment leading to apoptosis in Jurkat cells.

A. Vessières, G. Jaouen, P. Pigeon, 2017, Metallomics : integrated biometal science.

Synthetic strategy for organometallic complexes of rhenium with exceptionally high affinity for the oestradiol receptor; their potential use as imaging and therapeutic agents

A. Vessières, G. Jaouen, S. Top, 1994 .

Cytotoxic Triosmium Carbonyl Clusters: A Structure–Activity Relationship Study

A. Vessières, S. Top, W. Leong, 2014, ChemMedChem.

Pro‐oxidant Properties of AZT and other Thymidine Analogues in Macrophages: Implication of the Azido Moiety in Oxidative Stress

G. Jaouen, S. Top, Alaric C. W. Koh, 2010, ChemMedChem.

Synthesis and biodistribution of [99mTc]-N-[4-nitro-3-trifluoromethyl-phenyl] cyclopentadienyltricarbonyltechnetium carboxamide, a nonsteroidal antiandrogen flutamide derivative.

G. Jaouen, S. Top, Tesnim Dallagi, 2010, Metallomics : integrated biometal science.

Reaction of [Re(CO)6]+ cation with cyclopentadienylthallium derivatives. Formation of cyclopentadienylrheniumtricarbonyl derivatives via [Re(CO)3L3]+ (L = solvent)

G. Jaouen, S. Top, S. Masi, 2003 .

Synthesis of cyclopentadienyltricarbonylrhenium(I) carboxylic acid from perrhenate

G. Jaouen, S. Top, Jean-Sébastien M. Lehn, 1999 .

Rapid and mild synthesis of [Re2(CO)10] by reduction of [NH4][ReO4] at atmospheric CO pressure

G. Jaouen, S. Top, P. Morel, 1996 .

Decomplexation of Cyclopentadienylmanganese Tricarbonyls under Very Mild Conditions: A Novel Route to Substituted Cyclopentadienes and Their Application in Organometallic Synthesis

G. Jaouen, S. Top, A. McGlinchey, 2001 .

First anti-oestrogen in the cyclopentadienyl rhenium tricarbonyl series. Synthesis and study of antiproliferative effects

G. Leclercq, A. Vessières, G. Jaouen, 2001 .

Organometallic cluster analogues of tamoxifen: Synthesis and biochemical assay

A. Vessières, G. Jaouen, S. Top, 2006 .

Synthetic, structural, and reactivity studies of dirhenium carbonyl complexes of 17.alpha.-ethynylestradiol and phenylacetylene: variable-temperature carbon-13 NMR spectra and x-ray crystal structure of (.mu.-H)(.mu.-C.tplbond.C-R)Re2(CO)7(MeCN)

G. Jaouen, S. Top, J. Vaissermann, 1992 .

Diamagnetic anisotropy of organometallic moieties: .chi. values for M(CO)3 (M = Cr, Mo, W) and for ferrocene

G. Jaouen, S. Top, R. Burns, 1986 .

Metal carbonyl fragments as a new class of markers in molecular biology

A. Vessières, G. Jaouen, S. Top, 1985 .

Diastereoselectivity in the bakers yeast reduction of [1-2H](sorbaldehyde)Fe(CO)3

M. G. Palin, G. Jaouen, S. Top, 1996 .

Vibrational spectra of the organometallic estrogen‐receptor marker [3‐O‐(3‐hydroxypropyl)‐17β‐estradiol]‐α‐tricarbonylchromium(0) and related compounds

C. Cordier, A. Vessières, G. Jaouen, 1990 .

Oxidation of Cymantrene-Tagged Tamoxifen Analogues: Effect of Diphenyl Functionalization on the Redox Mechanism

M. Baik, G. Jaouen, S. Top, 2020 .

Selective functionalization of crown ethers via arene chromium tricarbonyl complexes

G. Jaouen, F. Meganem, S. Top, 2005 .

Relationship between serum cholinesterase activity and duration of succinylcholine action in subjects with the "usual" phenotype for the enzyme.

S. Top, D. Yücel, O. Erdemli, 1988, Clinical chemistry.

Electrochemical differentiation of .alpha.- and .beta.-diastereoisomers of the steroid hormone receptor marker 3-(benzyloxy)-17.beta.-hydroxyestra-1,3,5(10)-trienetricarbonylchromium

A. Bond, G. Jaouen, S. Top, 1989 .

Synthesis, spectroscopic, and X-ray structural study of aqua-bis(thymine-N1,N4)-ethylenediamine copper(II)dihydrate [Cu(Thy)2(en)(H2O)].2H2O

S. Top, F. Michaud, Yoann Rousselin, 2017 .

Antiplasmodial activity of iron(II) and ruthenium(II) organometallic complexes against Plasmodium falciparum blood parasites

G. Jaouen, P. Pigeon, S. Top, 2015, Memorias do Instituto Oswaldo Cruz.

Facile synthesis and strong antiproliferative activity of disubstituted diphenylmethylidenyl-[3]ferrocenophanes on breast and prostate cancer cell lines

A. Vessières, G. Jaouen, P. Pigeon, 2010 .

Antibacterial properties and mode of action of new triaryl butene citrate compounds.

G. Jaouen, Mehdi El Arbi, Karim Jellali, 2014, European journal of medicinal chemistry.

Atypical McMurry Cross-Coupling Reactions Leading to a New Series of Potent Antiproliferative Compounds Bearing the Key [Ferrocenyl-Ene-Phenol] Motif

G. Jaouen, P. Pigeon, S. Top, 2014, Molecules.

The effect of protic electron donor aromatic substituents on ferrocenic and [3]ferrocenophanic anilines and anilides: Some aspects of structure–activity relationship studies on organometallic compounds with strong antiproliferative effects

G. Jaouen, S. Top, C. Amatore, 2013 .

Ferrocifen Type Anticancer Drugs

A. Vessières, G. Jaouen, S. Top, 2016 .

Polypeptides associated with in vitro cyst formation of Blastocystis hominis.

S. Top, W. S. Wan-Yusoff, J. Mak, 2003, The Southeast Asian journal of tropical medicine and public health.

Organometallics as Potential Protein Labels: Pyrylium and Pyridinium Salts Bearing (C6H5)Cr(CO)3, (C5H4)Mn(CO)3, and Ferrocenyl Substituents

K. Malisza, S. Top, J. Saillard, 1995 .

[eta 5-Cyclopentadienyl]metal tricarbonyl pyrylium salts: novel reagents for the specific conjugation of proteins with transition organometallic labels.

K. Malisza, G. Jaouen, S. Top, 1994, Bioconjugate chemistry.

The first titanocenyl dichloride moiety vectorised by a selective estrogen receptor modulator (SERM). Synthesis and preliminary biochemical behaviour

G. Leclercq, A. Vessières, G. Jaouen, 2002 .

A New Series of Succinimido-ferrociphenols and Related Heterocyclic Species Induce Strong Antiproliferative Effects, Especially against Ovarian Cancer Cells Resistant to Cisplatin.

G. Jaouen, J. Bignon, P. Pigeon, 2017, Journal of medicinal chemistry.

Osmocenyl-tamoxifen derivatives target the thioredoxin system leading to a redox imbalance in Jurkat cells.

A. Vessières, G. Jaouen, S. Top, 2016, Journal of inorganic biochemistry.

Novel estradiol derivatives labeled with Ru, W, and Co complexes. Influence on hormone-receptor affinity of several organometallic groups at the 17 alpha position.

A. Vessières, G. Jaouen, S. Top, 2002, Chemistry.

Anodic properties of diarylethene derivatives having organometallic piano-stool tags.

G. Jaouen, S. Top, E. Hillard, 2011, Chemical communications.

UV‐Visible and Electrochemical Monitoring of Carbon Monoxide Release by Donor Complexes to Myoglobin Solutions and to Electrodes Modified with Films Containing Hemin

S. Top, J. Zagal, T. Nyokong, 2006 .

Surface grafting of a π-conjugated amino-ferrocifen drug

C. Combellas, F. Podvorica, A. Vessières, 2013 .

Atypical Lone Pair-π Interaction with Quinone Methides in a Series of Imido-Ferrociphenol Anticancer Drug Candidates.

I. Ciofini, G. Jaouen, P. Pigeon, 2019, Angewandte Chemie.

Atypical Lone Pair–π Interaction with Quinone Methides in a Series of Imido‐Ferrociphenol Anticancer Drug Candidates

I. Ciofini, G. Jaouen, P. Pigeon, 2019, Angewandte Chemie.

Deciphering the activation sequence of ferrociphenol anticancer drug candidates.

D. Mansuy, A. Vessières, G. Jaouen, 2012, Chemistry.

Synthesis of optically pure o-formylcyclopentadienyl metal complexes of 17α-ethynylestradiol. Recognition of the planar chirality by the estrogen receptor

A. Vessières, G. Jaouen, S. Top, 2006 .

Synthesis of tritium‐labeled (3)‐O‐(3‐hydroxypropyl)‐17α‐estradiol chromium tricarbonyl: The first radioactive transition metal carbonyl steroid hormone

A. Vessières, G. Jaouen, S. Top, 1987 .

Transition-metal carbonyl clusters as novel infrared markers for estradiol receptor site detection

A. Vessières, G. Jaouen, S. Top, 1987 .

Asymmetric biochemical reduction, acylation and hydrolysis in the (diene)Fe(CO)3 series: Experimental results and molecular modelling studies

M. G. Palin, G. Jaouen, S. Top, 1993 .

Biochemical resolution and generation of planar chirality in formyl substituted (diene)Fe(CO)3 complexes

M. G. Palin, G. Jaouen, S. Top, 1992 .

Synthesis and antiproliferative evaluation of ferrocenyl and cymantrenyl triaryl butene on breast cancer cells. Biodistribution study of the corresponding technetium-99m tamoxifen conjugate

A. Vessières, G. Jaouen, S. Top, 2013 .

New and efficient synthesis of CpRe(CO)3 substituted steroids

J. Marrot, G. Jaouen, S. Top, 2001 .

Direct Synthesis of Tricarbonyl(cyclopentadienyl)rhenium and Tricarbonyl(cyclopentadienyl)technetium Units from Ferrocenyl Moieties − Preparation of 17α‐Ethynylestradiol Derivatives Bearing a Tricarbonyl(cyclopentadienyl)technetium Group

G. Jaouen, S. Top, B. Spingler, 2004 .

Selection of a Suitable Disc Bioassay for the Screening of Anti-Tumor Molecules

Mehdi El Arbi, P. Pigeon, S. Top, 2013, International journal of biomedical science : IJBS.

Synthesis and antiproliferative activity of hydroxyferrocifen hybrids against triple-negative breast cancer cells.

A. Vessières, G. Jaouen, S. Top, 2014, Dalton transactions.

Intracellular Localization of an Osmocenyl-Tamoxifen Derivative in Breast Cancer Cells Revealed by Synchrotron Radiation X-ray Fluorescence Nanoimaging.

P. Cloetens, A. Vessières, G. Jaouen, 2019, Angewandte Chemie.

Analytical potential of near‐infrared fourier transform Raman spectra in the detection of solid transition metal carbonyl steroid hormones

A. Vessières, G. Jaouen, S. Top, 1995 .

Role of aromatic substituents on the antiproliferative effects of diphenyl ferrocenyl butene compounds.

A. Vessières, G. Jaouen, P. Pigeon, 2009, Dalton transactions.

A new efficient route to chiral 1,3-disubstituted ferrocenes: application to the syntheses of (R(p))- and (S(p))-17alpha-[(3'-formylferrocenyl)ethynyl]estradiol.

G. Jaouen, S. Top, R. Welter, 2006, Chemistry.

Introduction of a planar chirality onto steroid substrates: synthesis of (S) and (R)-2'-formylcymantrenyl-17α-ethynylestradiols using (S) and (R)-1-formyl-2-iodo-cymantrenes

G. Jaouen, S. Top, Benoît Ferber, 2004 .

Aryl Butenes Active against K562 Cells and Lacking Tyrosinase Inhibitory Activity as New Leads in the Treatment of Leukemia.

A. Gargouri, G. Jaouen, E. Ketata, 2017, Mini reviews in medicinal chemistry.

Efficacy of a novel ferrocenyl diaryl butene citrate compound as a biocide for preventing healthcare-associated infections

G. Jaouen, P. Pigeon, S. Top, 2016 .

New Synthetic Pathways of cis- or trans-Hydroxytamoxifen Derivatives with in Situ Formed [Cp*Rh(solvent)3]2+ Complexes: Kinetic and Thermodynamic Control, Including a Novel, Intramolecular N-π Rearrangement, and Relative Binding Affinities of the η6 Complexes for the Estrogen Receptor

A. Vessières, G. Jaouen, S. Top, 2006 .

Intracellular Localization of an Osmocenyl-Tamoxifen Derivative in Breast Cancer Cells Revealed by Synchrotron Radiation X-ray Fluorescence Nanoimaging.

P. Cloetens, A. Vessières, G. Jaouen, 2019, Angewandte Chemie.

Synthetic and mechanistic pathways of cis and trans-hydroxytamoxifen drug derivatives reacting with Cp*Rh complexes that involve η1-N, η2-N,O, η1-O, and η6 bonding modes, via a novel N-π rearrangement; relative binding affinities and computer docking studies of cis and trans-η6-Cp*Rh-hydroxytamoxife

P. Yaswen, A. Vessières, G. Jaouen, 2011, Inorganic chemistry.

Synthesis and biodistribution of 1-[2-(cyclopentadienyltricarbonyltechnetium-99m)-2-oxo-ethoxy-phenyl]-1,2-di- (p-hydroxyphenyl)but-1-ene for tumor imaging

G. Jaouen, S. Top, Tesnim Dallagi, 2019, Journal of Organometallic Chemistry.

Inhibition of cathepsin B by ferrocenyl indenes highlights a new pharmacological facet of ferrocifens

Isabelle Navizet, A. Vessières, G. Jaouen, 2022, European Journal of Inorganic Chemistry.

A short route to cyclopentadienyltricarbonylrhenium substituted derivatives

G. Jaouen, P. Pigeon, S. Top, 2003 .

New Ortho-Directing Group for Lithiation: Use of a Methoxy−Imino Auxiliary for the Synthesis of Chiral Ortho-Substituted Acetyl- and Propionylferrocenes

G. Jaouen, S. Top, Benoît Ferber, 2007 .

Oxidative Metabolism of Ferrocene Analogues of Tamoxifen: Characterization and Antiproliferative Activities of the Metabolites

D. Mansuy, A. Vessières, G. Jaouen, 2015, ChemMedChem.