Zhaomin Liu

发表

Discovery of ERD-308 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Estrogen Receptor (ER).

Shaomeng Wang, Chao-yie Yang, James Delproposto, 2019, Journal of medicinal chemistry.

Understanding P450-mediated Bio-transformations into Epoxide and Phenolic Metabolites.

P. Labute, N. Moitessier, Zhaomin Liu, 2015, Angewandte Chemie.

A platinum(II) phenylphenanthroimidazole with an extended side-chain exhibits slow dissociation from a c-Kit G-quadruplex motif.

A. Mittermaier, N. Moitessier, H. Sleiman, 2013, Chemistry.

Discovery of M-1121 as an Orally Active Covalent Inhibitor of Menin-MLL Interaction Capable of Achieving Complete and Long-Lasting Tumor Regression.

Shaomeng Wang, S. Gross, J. Stuckey, 2021, Journal of medicinal chemistry.

Elucidating Hyperconjugation from Electronegativity to Predict Drug Conformational Energy in a High Throughput Manner

Paul Labute, Nicolas Moitessier, Joshua Pottel, 2016, J. Chem. Inf. Model..

Use of Extended-Hückel Descriptors for Rapid and Accurate Predictions of Conjugated Torsional Energy Barriers

Paul Labute, Nicolas Moitessier, Stephen J Barigye, 2020, J. Chem. Inf. Model..

Torsional Energy Barriers of Biaryls Could Be Predicted by Electron Richness/Deficiency of Aromatic Rings; Advancement of Molecular Mechanics toward Atom-Type Independence

Paul Labute, Nicolas Moitessier, Stephen J Barigye, 2019, J. Chem. Inf. Model..

A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo.

Liu Liu, Shaomeng Wang, J. Stuckey, 2019, Cancer cell.

A Structure-Based Approach to Understanding Somatostatin Receptor-4 Agonism (sst4)

Christina Hayes, Daniel Ansbro, Maria Kontoyianni, 2012, J. Chem. Inf. Model..

Discovery of M-808 as a Highly Potent, Covalent, Small-Molecule Inhibitor of the Menin-MLL Interaction with Strong In Vivo Antitumor Activity.

Shaomeng Wang, J. Stuckey, D. McEachern, 2020, Journal of medicinal chemistry.

Structure-Based Discovery of SD-36 as a Potent, Selective and Efficacious PROTAC Degrader of STAT3 Protein.

Liu Liu, Shaomeng Wang, J. Stuckey, 2019, Journal of medicinal chemistry.

Simple Structural Modifications Converting a Bona Fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders.

Zhaomin Liu, Shaomeng Wang, A. Aguilar, 2019, Journal of medicinal chemistry.

Atom Type Independent Modeling of the Conformational Energy of Benzylic, Allylic, and Other Bonds Adjacent to Conjugated Systems

Paul Labute, Nicolas Moitessier, Stephen J Barigye, 2019, J. Chem. Inf. Model..

Medicinal Chemistry Projects Requiring Imaginative Structure-Based Drug Design Methods.

Christopher R. Corbeil, Nicolas Moitessier, Pablo Englebienne, 2016, Accounts of chemical research.