J. Alsenz

发表

Interactions of dimethylaminoethyl methacrylate copolymer with non‐acidic drugs demonstrated high solubilization in vitro and pronounced sustained release in vivo

M. Kuentz, Wiebke Saal, Nicole Wyttenbach, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Benzodioxoles: novel cannabinoid-1 receptor inverse agonists for the treatment of obesity.

Wolfgang Guba, Gisbert Schneider, Jochem Alsenz, 2008, Journal of medicinal chemistry.

Protein Aggregates Seem to Play a Key Role Among the Parameters Influencing the Antigenicity of Interferon Alpha (IFN-α) in Normal and Transgenic Mice

Jochem Alsenz, M. Labow, J. Alsenz, 1997, Pharmaceutical Research.

High throughput solubility measurement in drug discovery and development.

Manfred Kansy, Jochem Alsenz, M. Kansy, 2007, Advanced drug delivery reviews.

Miniaturized X-ray powder diffraction assay (MixRay) for quantitative kinetic analysis of solvent-mediated phase transformations in pharmaceutics.

M. Kuentz, Nicole Wyttenbach, J. Alsenz, 2016, Journal of pharmaceutical and biomedical analysis.

The Impact of Solubility and Dissolution Assessment on Formulation Strategy and Implications for Oral Drug Disposition

Jochem Alsenz, J. Alsenz, 2012 .

Drug-Excipient Compatibility Testing Using a High-Throughput Approach and Statistical Design

Martin Kuentz, Jochem Alsenz, Nicole Wyttenbach, 2005, Pharmaceutical development and technology.

Miniaturized Assay for Solubility and Residual Solid Screening (SORESOS) in Early Drug Development

Jochem Alsenz, Nicole Wyttenbach, Nicole Wyttenbach, 2007, Pharmaceutical Research.

Development of a partially automated solubility screening (PASS) assay for early drug development.

Jochem Alsenz, J. Alsenz, Elisabeth Haenel, 2007, Journal of pharmaceutical sciences.

Interferon immunogenicity: preclinical evaluation of interferon-alpha 2a.

S. Pestka, M. Labow, J. Alsenz, 1997, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

From Quantum Chemistry to Prediction of Drug Solubility in Glycerides.

M. Kuentz, J. Alsenz, 2019, Molecular pharmaceutics.

Structural and functional analysis of C3 using monoclonal antibodies.

B. Nilsson, J. Lambris, J. Alsenz, 1990, Current topics in microbiology and immunology.

The quest for exceptional drug solubilization in diluted surfactant solutions and consideration of residual solid state

M. Kuentz, Wiebke Saal, Nicole Wyttenbach, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Oral Absorption of Peptides Through the Cobalamin (Vitamin B12) Pathway in the Rat Intestine

Steven Westwood, Jochem Alsenz, J. Alsenz, 2000, Pharmaceutical Research.

Segment spanning residues 727-768 of the complement C3 sequence contains a neoantigenic site and accommodates the binding of CR1, factor H, and factor B.

J. Lambris, C. Hack, J. Alsenz, 1992, Biochemistry.

Active Apical Secretory Efflux of the HIV Protease Inhibitors Saquinavir and Ritonavir in Caco-2 Cell Monolayers

J. Alsenz, Rainer Alex, H. Steffen, 1998, Pharmaceutical Research.

Risdiplam distributes and increases SMN protein in both the central nervous system and peripheral organs

S. Bassett, S. Paushkin, J. Alsenz, 2018, Pharmacology research & perspectives.

Autoantibody-mediated acquired deficiency of C1 inhibitor.

J. Alsenz, K. Bork, M. Loos, 1987, The New England journal of medicine.

Cell surface proteins reacting with activated complement components.

John D Lambris, J. Lambris, B. Myones, 1989, Complement and inflammation.

The critical concentration of C1-esterase inhibitor (C1-INH) in human serum preventing auto-activation of the first component of complement (C1).

J. Alsenz, M. Loos, J. Windfuhr, 2005, Molecular immunology.

Acquired angioedema and anti-C1-inhibitor autoantibody.

B. Wüthrich, J. Alsenz, P. Späth, 1989, Archives of internal medicine.

Role of C3b receptors in the enhancement of interleukin-2-dependent T-cell proliferation.

T. Schulz, J. Alsenz, J. Gergely, 1984, Molecular immunology.

Acquired C1 inhibitor (C1-INH) deficiency type II. Replacement therapy with C1-INH and analysis of patients' C1-INH and anti-C1-INH autoantibodies.

John D Lambris, J. Lambris, J. Alsenz, 1989, The Journal of clinical investigation.

Use of synthetic peptides in exploring and modifying complement reactivities

John D Lambris, J. Lambris, J. Alsenz, 1993 .

Activators and Inhibitors of Complement

J. Alsenz, Charles McIntosh, Sim, 1993, Springer Netherlands.

Molecular aspects of C3 interactions and structural/functional analysis of C3 from different species.

John D Lambris, J. Lambris, J. Alsenz, 1990, Current topics in microbiology and immunology.

UNGAP best practice for improving solubility data quality of orally administered drugs.

A. Bauer-Brandl, J. Alsenz, P. Augustijns, 2021, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Estimation of permeability by passive diffusion through Caco-2 cell monolayers using the drugs' lipophilicity and molecular weight.

G Folkers, H. van de Waterbeemd, G. Folkers, 1998, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The role of surfactants in the reversal of active transport mediated by multidrug resistance proteins.

Jochem Alsenz, J. Alsenz, J. Drewe, 2003, Journal of pharmaceutical sciences.

Can we estimate the critical micelle concentration of amphiphilic drug bases from molecular connectivity indices?

M. Kuentz, Wiebke Saal, Nicole Wyttenbach, 2018, Pharmaceutical development and technology.

Atomic Force Microscopy-Based Screening of Drug-Excipient Miscibility and Stability of Solid Dispersions

Jochem Alsenz, Susanne Page, Andreas Engel, 2010, Pharmaceutical Research.

Coupling of C3b to erythrocytes by disulfide bond formation: preparation of EC3b for hemolytic and complement receptor assays.

J. Lambris, T. Schulz, J. Alsenz, 1983, Journal of immunological methods.

Autoantibodies against complement components and their effects on complement activity

J. Alsenz, H. Heinz, M. Loos, 1993 .

Phylogeny of the third component of complement, C3: analysis of the conservation of human CR1, CR2, H, and B binding sites, concanavalin A binding sites, and thiolester bond in the C3 from different species.

J. Lambris, T. Kinoshita, J. Alsenz, 1992, Developmental and comparative immunology.

Acquired C 1 Inhibitor ( Cl-INH ) Deficiency Type 11 Replacement Therapy with C 1-INH and Analysis of Patients ' C 1-INH and Anti-Cl-INH Autoantibodies

John D Lambris, J. Lambris, J. Alsenz, 2013 .

The acquired C1-INH deficiencies with autoantibodies (AAE type II).

J. Alsenz, M. Loos, 1989, Behring Institute Mitteilungen.

Third component of trout complement. cDNA cloning and conservation of functional sites.

J. Lambris, J. Alsenz, J. Pang, 1993, Journal of immunology.

Unexpected Solubility Enhancement of Drug Bases in the Presence of a Dimethylaminoethyl Methacrylate Copolymer.

M. Kuentz, Wiebke Saal, Nicole Wyttenbach, 2018, Molecular pharmaceutics.

A Systematic Study of Molecular Interactions of Anionic Drugs with a Dimethylaminoethyl Methacrylate Copolymer Regarding Solubility Enhancement.

M. Kuentz, Wiebke Saal, Nicole Wyttenbach, 2017, Molecular pharmaceutics.

Miniaturized INtrinsic DISsolution Screening (MINDISS) assay for preformulation.

Jochem Alsenz, Giorgio Cirelli, J. Alsenz, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Structural and functional analysis of the complement component factor H with the use of different enzymes and monoclonal antibodies to factor H.

J. Lambris, T. Schulz, Robert B Sim, 1985, The Biochemical journal.

P‐Glycoprotein and Surfactants: Effect on Intestinal Talinolol Absorption

Gérard Hopfgartner, Jochem Alsenz, J. Alsenz, 2005, Clinical pharmacology and therapeutics.

Development and Use of Enzyme-Linked Immunosorbent Assays (ELISA) for the Detection of Protein Aggregates in Interferon-Alpha (IFN-α) Formulations

J. Alsenz, A. Braun, 1997, Pharmaceutical Research.

Importance of factors H and I for the adherence of C3b-coated erythrocytes to cells.

J. Lambris, T. Schulz, J. Alsenz, 1983, Immunobiology.

A comparative evaluation of receptor reactivities for C3b, iC3b, and C3d on Raji lymphoblastoid cells.

T. Schulz, J. Alsenz, M. Dierich, 1982, International archives of allergy and applied immunology.

USE OF MONOCLONAL ANTIBODIES AGAINST FACTOR H TO INVESTIGATE THE ROLE OF A MEMBRANE-ASSOCIATED PROTEIN ANTIGENICALLY RELATED TO H IN C 3 b-RECEPTOR FUNCTION '

J. Lambris, T. Schulz, J. Alsenz, 2001 .