R. Sorenson

发表

Direct and Systemic Administration of a CNS-Permeant Tamoxifen Analog Reduces Amphetamine-Induced Dopamine Release and Reinforcing Effects

R. Kennedy, C. Carpenter, Alexander G. Zestos, 2017, Neuropsychopharmacology.

Design and synthesis of triarylacrylonitrile analogues of tamoxifen with improved binding selectivity to protein kinase C.

T. Cierpicki, C. Carpenter, R. Sorenson, 2016, Bioorganic & medicinal chemistry.

Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.

R. D. Dyer, A. Sercel, K. Chan, 1999, Journal of medicinal chemistry.

R. D. Dyer, A. Sercel, R. Gilbertsen, 1999, Journal of medicinal chemistry.

Synthesis and antiallergy activity of 10-oxo-10H-pyrido[1,2-a]thieno[3,2-d]pyrimidines and 10-oxo-10H-pyrido[1,2-a]thieno[3,4-d]pyrimidines.

R. Sorenson, J. Kerbleski, D. T. Connor, 1984, Journal of medicinal chemistry.

Pyrazole inhibitors of HMG-CoA reductase: an attempt to dramatically reduce synthetic complexity through minimal analog re-design.

B. Tait, M. Kowala, G. Lu, 2007, Bioorganic & medicinal chemistry letters.

Novel inhibitors of bacterial virulence: development of 5,6-dihydrobenzo[h]quinazolin-4(3H)-ones for the inhibition of group A streptococcal streptokinase expression.

R. Sorenson, Wenpeng Zhang, Duxin Sun, 2013, Bioorganic & medicinal chemistry.

Synthesis and SAR of selective benzothiophene, benzofuran, and indole-based peroxisome proliferator-activated receptor δ agonists

G. Lu, R. Sorenson, P. Unangst, 2007 .

Kynurenic acid derivatives inhibit the binding of nerve growth factor (NGF) to the low-affinity p75 NGF receptor.

R. Davis, J. Marks, R. Sorenson, 1995, Journal of medicinal chemistry.

Preparation of 3-amino-2,3,6-trideoxy-D-arabino-hexose hydrochloride and its N-trifluoroacetyl derivative.

R. Sorenson, D. Horton, W. Weckerle, 1977, Carbohydrate research.

Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors.

G. Lu, J. Pfefferkorn, M. Harris, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of 5-[[3,5-bis(1,1-dimethylethyl)- 4-hydroxyphenyl]methylene]oxazoles, -thiazoles, and -imidazoles: novel dual 5-lipoxygenase and cyclooxygenase inhibitors with antiinflammatory activity.

R. D. Dyer, R. Sorenson, R. Dyer, 1994, Journal of medicinal chemistry.

Synthesis and antiallergy activity of 4-oxo-4H-pyrido[1,2-a]thieno[2,3-d]pyrimidines.

R. Sorenson, J. Kerbleski, D. T. Connor, 1981, Journal of medicinal chemistry.

Novel thiophene-, pyrrole-, furan-, and benzenecarboxamidotetrazoles as potential antiallergy agents.

M. D. Mullican, R. Sorenson, D. T. Connor, 1991, Journal of medicinal chemistry.

3-(aminoalkyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c] pyridin-5-ones as potential anticholinergic bronchodilators.

R. Sorenson, D. T. Connor, P. Unangst, 1989, Journal of medicinal chemistry.

Syntheses of 10‐Oxo‐10H‐pyrido[1,2‐a]thieno[3,4‐d]pyrimidines and 10‐Oxo‐10H‐pyrido[1,2‐a]thieno[3,2‐d]pyrimidines from methyl tetrahydro‐4‐oxo‐3‐thiophenecarboxylate and methyl tetrahydro‐3‐oxo‐2‐thiophenecarboxylate, respectively

R. Sorenson, J. Kerbleski, D. T. Connor, 1982 .

Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia.

Jolanta Grembecka, Thomas Hartley, J. Hess, 2012, Nature chemical biology.

Synthesis and Biological Evaluation of 5-((3,5-Bis(1,1-dimethylethyl)- 4-hydroxyphenyl)methylene)oxazoles, -thiazoles, and -imidazoles: Novel Dual 5-Lipoxygenase and Cyclooxygenase Inhibitors with Antiinflammatory Activity.

R. D. Dyer, R. Sorenson, R. Dyer, 1994 .

Oxazole, thiazole, and imidazole derivatives of 2,6-di-tert-butylphenol as dual 5-lipoxygenase and cyclooxygenase inhibitors

R. D. Dyer, R. Sorenson, R. Dyer, 1993 .

Substituted oxazolidinones as novel NPC1L1 ligands for the inhibition of cholesterol absorption.

J. Pfefferkorn, R. Sorenson, Thomas J. Winters, 2008, Bioorganic & medicinal chemistry letters.

Copper(II)(3,5‐Diisopropylsalicylate)2 Accelerates Recovery of B and T Cell Reactivity Following Irradiation

J. Barnett, R. Sorenson, H. Salari, 1987, Scandinavian journal of immunology.

The synthesis of 3-amino-2,3,6-trideoxy-l-xylo-hexopyranose derivatives☆

R. Sorenson, D. Horton, W. Weckerle, 1978 .

Novel Inhibitors of Staphylococcus aureus Virulence Gene Expression and Biofilm Formation

Meng Chen, R. Sorenson, S. Larsen, 2012, PloS one.

Inhibition of E-selectin-, ICAM-1-, and VCAM-1-mediated cell adhesion by benzo[b]thiophene-, benzofuran-, indole-, and naphthalene-2-carboxamides: identification of PD 144795 as an antiinflammatory agent.

D. Boschelli, R. Sorenson, D. T. Connor, 1995, Journal of medicinal chemistry.

Novel benzothiophene-, benzofuran-, and naphthalenecarboxamidotetrazoles as potential antiallergy agents.

M. D. Mullican, R. Sorenson, D. T. Connor, 1992, Journal of medicinal chemistry.

Enediol mimics as inhibitors of the D-arabinose 5-phosphate isomerase (KdsD) from Francisella tularensis.

P. Keller, R. Sorenson, H. Showalter, 2011, Bioorganic & medicinal chemistry letters.

A novel small molecule deubiquitinase inhibitor blocks Jak2 signaling through Jak2 ubiquitination.

A. Levitzki, N. Donato, W. Bornmann, 2011, Cellular signalling.

RecO and RecR Are Necessary for RecA Loading in Response to DNA Damage and Replication Fork Stress

R. Sorenson, H. Showalter, Lyle A. Simmons, 2014, Journal of bacteriology.

Kynurenic Acid Derivatives Inhibit the Binding of Nerve Growth Factor ( NGF) to the Low‐Affinity p75 NGF Receptor.

J. Marks, R. Sorenson, J. Fergus, 1996 .

R. D. Dyer, A. Sercel, K. Chan, 1999, Journal of medicinal chemistry.

Inhibition of E-Selectin-, ICAM-1, and VCAM-1-Mediated Cell Adhesion by Benzo(b)thiophene-, Benzofuran-, Indole-, and Naphthalene-2- carboxamides: Identification of PD 144795 as an Antiinflammatory Agent.

D. Boschelli, R. Sorenson, D. T. Connor, 1996 .

Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma.

R. Neubig, D. Khanna, R. Sorenson, 2017, Bioorganic & medicinal chemistry letters.

Synthesis via pummerer intermediates. IV. Synthesis of 1‐(4‐hydroxy‐2‐oxo‐2H‐1‐benzopyran‐3‐yl)pyridinium hydroxide inner salt derivatives and 3‐(2H)benzofuranones by the action of phosgene in pyridine on 2‐hydroxy‐1‐[(methylsulfinyl)acetyl]benzene derivatives

R. Sorenson, D. Connor, 1981 .

SYNTHESIS VIA PUMMERER INTERMEDIATES. IV. SYNTHESIS OF 1-(4-HYDROXY-2-OXO-2H-1-BENZOPYRAN-3-YL)PYRIDINIUM HYDROXIDE INNER SALT DERIVATIVES AND 3-(2H)BENZOFURANONES BY THE ACTION OF PHOSGENE IN PYRIDINE ON 2-HYDROXY-1-((METHYLSULFINYL)

R. Sorenson, D. Connor, 1981 .

2,6-di-tert-butylphenols: A new class of potent and selective PGHS-2 inhibitor

R. D. Dyer, A. Sercel, K. Chan, 1997, Inflammation Research.