R. Callis

发表

Investigation of (E)-3-[4-(2-Oxo-3-aryl-chromen-4-yl)oxyphenyl]acrylic Acids as Oral Selective Estrogen Receptor Down-Regulators.

R. A. Norman, James S. Scott, A. Bailey, 2015, Journal of medicinal chemistry.

Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist.

A. Rabow, D. M. Andrews, G. Walker, 2015, Journal of medicinal chemistry.

The nucleotide sequence of an infectious clone of the geminivirus beet curly top virus

R. Callis, P. Markham, M. Pinner, 1986, The EMBO journal.

Cloning and expression in Escherichia coli of a Streptomyces coelicolor A3(2) argCJB gene cluster.

B. Rudd, R. Callis, S. Baumberg, 1994, Microbiology.

AZD8931, an Equipotent, Reversible Inhibitor of Signaling by Epidermal Growth Factor Receptor, ERBB2 (HER2), and ERBB3: A Unique Agent for Simultaneous ERBB Receptor Blockade in Cancer

Paul D. Smith, R. Wilkinson, B. Barlaam, 2010, Clinical Cancer Research.

Optimization of a Series of Bivalent Triazolopyridazine Based Bromodomain and Extraterminal Inhibitors: The Discovery of (3R)-4-[2-[4-[1-(3-Methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-piperidyl]phenoxy]ethyl]-1,3-dimethyl-piperazin-2-one (AZD5153).

C. A. Roberts, A. Rabow, M. Waring, 2016, Journal of medicinal chemistry.

Running title : Pharmacology of SERD inhibitor in breast cancer models

Graham, A. Rabow, R. A. Norman, 2016 .

The Relationship Between Primary and Secondary Metabolism in Streptomycetes

A. Corner, R. Callis, S. Baumberg, 1991 .

Delimitation of essential genes of cassava latent virus DNA 2.

R. Callis, J. Stanley, S. Ellwood, 1988, Nucleic acids research.

Potent and selective bivalent inhibitors of BET bromodomains.

A. Dulak, A. Rabow, M. Waring, 2016, Nature chemical biology.

A Screening Assay Cascade to Identify and Characterize Novel Selective Estrogen Receptor Downregulators (SERDs)

A. Rabow, G. Walker, R. Callis, 2015, Journal of biomolecular screening.

Light-Dependent Growth and Differentiation Processes in Photoautotrophic Cell Cultures

R. Callis, H. Herzbeck, S. Amino, 1990 .

AZD9496: An Oral Estrogen Receptor Inhibitor That Blocks the Growth of ER-Positive and ESR1-Mutant Breast Tumors in Preclinical Models.

A. Rabow, G. Walker, R. A. Norman, 2016, Cancer research.

Abstract DDT01-03: Discovery and pre-clinical pharmacology of AZD9496: An oral, selective estrogen receptor down-regulator (SERD)

A. Rabow, D. M. Andrews, G. Walker, 2015 .

Abstract 5365: Molecular and pharmacological (EGFRi, MEKi) characterisation of a colorectal cancer (CRC) cell line panel to evaluate cellular phenotype and efficacy of targeted therapies in CRC

S. Runswick, C. Chresta, R. Wilkinson, 2011 .

Implementation and Challenges of Direct Acoustic Dosing into Cell-Based Assays

Karen Roberts, Rowena Callis, Tim Ikeda, 2016, Journal of laboratory automation.