Christopher D. Chien

发表

COREGULATORS AND THEIR ROLE IN SELECTIVE ESTROGEN RECEPTOR MODULATOR ACTION

A. Wellstein, A. Riegel, Christopher D. Chien, 2013 .

Role of the Nuclear Receptor Coactivator AIB1-Δ4 Splice Variant in the Control of Gene Transcription*

A. Wellstein, A. Riegel, T. Lahusen, 2011, The Journal of Biological Chemistry.

Regulation of HER2 oncogene transcription by a multifunctional coactivator/corepressor complex.

A. Wellstein, A. Riegel, Christopher D. Chien, 2014, Molecular endocrinology.

Tyrosine Phosphorylation of the Nuclear Receptor Coactivator AIB1/SRC-3 Is Enhanced by Abl Kinase and Is Required for Its Activity in Cancer Cells

Sivanesan Dakshanamurthy, Anton Wellstein, John T. Lahusen, 2008, Molecular and Cellular Biology.

expansion after BMT immunity from T-cell populations undergoing homeostatic peripheral oligodeoxynucleotides and IL-2 generate antigen-specific antitumor Vaccination regimens incorporating CpG-containing

Christopher D. Chien, J. Kochenderfer, R. Gress, 2013 .

Vaccination regimens incorporating CpG-containing oligodeoxynucleotides and IL-2 generate antigen-specific antitumor immunity from T-cell populations undergoing homeostatic peripheral expansion after BMT.

Christopher D. Chien, J. Kochenderfer, R. Gress, 2007, Blood.

Murine allogeneic CD19 CAR T cells harbor potent antileukemic activity but have the potential to mediate lethal GVHD.

T. Fry, Christopher D. Chien, Yinmeng Yang, 2016, Blood.

Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design

N. Taylor, T. Fry, Christopher D. Chien, 2021, Journal for ImmunoTherapy of Cancer.

Il-6 is non-essential to murine CD19 CAR efficacy, but can mediate acute GVHD following allogeneic BMT with CAR T cell infusion

T. Fry, Christopher D. Chien, Yinmeng Yang, 2015, Journal of Immunotherapy for Cancer.

Maximizing CD8+ T cell responses elicited by peptide vaccines containing CpG oligodeoxynucleotides.

Christopher D. Chien, J. Kochenderfer, R. Gress, 2007, Clinical immunology.

Synergism between CpG-Containing Oligodeoxynucleotides and IL-2 Causes Dramatic Enhancement of Vaccine-Elicited CD8+ T Cell Responses1

Christopher D. Chien, J. Kochenderfer, R. Gress, 2006, The Journal of Immunology.

Dramatic Enhancement of Vaccine-Elicited Oligodeoxynucleotides and IL-2 Causes Synergism between CpG-Containing Simpson and

Christopher D. Chien, J. Kochenderfer, R. Gress, 2006 .

An acetylation switch regulates SUMO-dependent protein interaction networks.

M. Avantaggiati, Christopher D. Chien, S. Muller, 2012, Molecular cell.

Absence of STAT1 in donor-derived plasmacytoid dendritic cells results in increased STAT3 and attenuates murine GVHD.

J. Khan, L. Hennighausen, T. Fry, 2014, Blood.

Potent preclinical activity of FLT3-directed chimeric antigen receptor T-cell immunotherapy against FLT3-mutant acute myeloid leukemia and KMT2A-rearranged acute lymphoblastic leukemia

T. Fry, Christopher D. Chien, S. Tasian, 2022, Haematologica.

Preclinical Development of FLT3-Redirected Chimeric Antigen Receptor T Cell Immunotherapy for Acute Myeloid Leukemia

D. Dimitrov, T. Fry, F. Shen, 2016 .

TCR engagement negatively affects CD8 but not CD4 CAR T cell expansion and leukemic clearance

Ying Hu, Chunhua Yan, T. Fry, 2017, Science Translational Medicine.

Murine Models of Acute Leukemia: Important Tools in Current Pediatric Leukemia Research

T. Fry, Christopher D. Chien, E. Jacoby, 2014, Front. Oncol..

Transcriptional repression of AIB1 by FoxG1 leads to apoptosis in breast cancer cells.

A. Wellstein, Jianming Xu, A. Riegel, 2013, Molecular endocrinology.

Role of the nuclear receptor coactivator AIB1/SRC-3 in angiogenesis and wound healing.

A. Wellstein, Jianming Xu, A. Riegel, 2012, The American journal of pathology.

CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity

J. Khan, A. Seif, B. Gryder, 2016, Nature Communications.

PU.1 supports proliferation of immature erythroid progenitors.

E. Scott, Christopher D. Chien, W. Slayton, 2004, Leukemia research.

Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients.

N. Taylor, H. Young, T. Fry, 2020, The Journal of clinical investigation.

Lineage Switch As a Relapse Mechanism of Pre-B Acute Lymphoblastic Leukemia Following CD19 CAR

T. Fry, Christopher D. Chien, Yinmeng Yang, 2015 .

The functional interplay between systemic cancer and the hematopoietic stem cell niche.

Deric M. Park, M. Gilbert, Amber J. Giles, 2016, Pharmacology & therapeutics.

Targeting of the Nuclear Receptor Coactivator Isoform DELTA3AIB1 in Breast Cancer

Christopher D. Chien, 2007 .

Determination of the effect of target site density on the efficacy of CD22 chimeric antigen receptor t-cell therapy to treat acute lymphoblastic leukemia.

T. Fry, Christopher D. Chien, Haiying Qin, 2016 .

CRLF2 /Tslpr Overexpressing Acute Lymphoblastic Leukemia Relapse Is Driven By Chemotherapy-Induced TSLP from Bone Marrow Stromal Cells

T. Fry, Christopher D. Chien, E. Jacoby, 2015 .

CD19/22 CAR T-cells in Children and Young Adults with B-ALL: Phase I Results and Development of a Novel Bicistronic CAR.

S. Steinberg, G. Altan-Bonnet, D. Stroncek, 2022, Blood.

Evaluating on-Target Toxicity of Hematopoietic-Targeting Cars Demonstrates Target-Nonspecific Suppression of Marrow Progenitors

T. Fry, F. Shen, Christopher D. Chien, 2016 .

An acetylation switch regulates SUMO-dependent protein interaction networks.

M. Avantaggiati, Christopher D. Chien, S. Muller, 2012, Molecules and Cells.

Role of the Nuclear Receptor Coactivator AIB1-Δ4 Splice Variant in the Control of Gene Transcription*

A. Wellstein, A. Riegel, T. Lahusen, 2011, The Journal of Biological Chemistry.