D. Passarella

发表

Synthesis and biological evaluation of novel tamoxifen analogues.

M. Christodoulou, N. Fokialakis, D. Passarella, 2013, Bioorganic & medicinal chemistry.

Chalcones and Chalcone-mimetic Derivatives as Notch Inhibitors in a Model of T-cell Acute Lymphoblastic Leukemia.

I. Screpanti, M. Mori, M. Christodoulou, 2019, ACS medicinal chemistry letters.

Chiral Flavanones from Amygdalus lycioides Spach: Structural Elucidation and Identification of TNFalpha Inhibitors by Bioactivity-guided Fractionation

D. Rossi, S. Collina, M. Christodoulou, 2012, Molecules.

Probing an Allosteric Pocket of CDK2 with Small Molecules

L. Lo Presti, G. Rastelli, M. Broggini, 2017, ChemMedChem.

N‐[2‐Methyl‐5‐(triazol‐1‐yl)phenyl]pyrimidin‐2‐amine as a Scaffold for the Synthesis of Inhibitors of Bcr‐Abl

E. Crespan, I. Filippi, G. Maga, 2011, ChemMedChem.

Synthesis and Investigation of the G-Quadruplex Binding Properties of Kynurenic Acid Derivatives with a Dihydroimidazoquinoline-3,5-dione Core

P. Perego, L. Musso, S. Dallavalle, 2022, Molecules.

Comparative phytochemical and morphological analyses of three Italian Primula species.

D. Passarella, G. Flamini, G. Fico, 2007, Phytochemistry.

Microtubule Alterations Occur Early in Experimental Parkinsonism and The Microtubule Stabilizer Epothilone D Is Neuroprotective

D. Passarella, G. Battaglia, G. Pezzoli, 2013, Scientific Reports.

A High-throughput Screening of a Chemical Compound Library in Ovarian Cancer Stem Cells.

M. Mori, B. Kamińska, N. Westwood, 2018, Combinatorial chemistry & high throughput screening.

Efficient continuous flow synthesis of hydroxamic acids and suberoylanilide hydroxamic acid preparation.

Daniele Vigo, Marisa Martinelli, Daniele Passarella, 2009, The Journal of organic chemistry.

Synthesis of (+)-dumetorine and congeners by using flow chemistry technologies.

D. Passarella, S. Gagliardi, Anna Rencurosi, 2011, Chemistry.

Histone deacetylase and microtubules as targets for the synthesis of releasable conjugate compounds.

F. Zunino, D. Passarella, B. Danieli, 2009, Bioorganic & medicinal chemistry letters.

Efficient Continuous Flow Synthesis of Hydroxamic Acids and Suberoylanilide Hydroxamic Acid (VII) Preparation.

D. Passarella, D. Vigo, S. Gagliardi, 2009 .

Cannabidiol as the Substrate in Acid-Catalyzed Intramolecular Cyclization

D. Passarella, David Coppini, M. Luzzani, 2020, Journal of natural products.

Nanolipid-Trehalose Conjugates and Nano-Assemblies as Putative Autophagy Inducers

P. Seneci, M. Christodoulou, D. Passarella, 2019, Pharmaceutics.

2‐Phenyloxazole‐4‐carboxamide as a Scaffold for Selective Inhibition of Human Monoamine Oxidase B

G. Rastelli, M. Christodoulou, D. Passarella, 2019, ChemMedChem.

Heteronanoparticles by Self-Assembly of Ecdysteroid and Doxorubicin Conjugates To Overcome Cancer Resistance.

M. Montopoli, M. Christodoulou, D. Passarella, 2018, ACS medicinal chemistry letters.

Heteronanoparticles by self-Assembly of Doxorubicin and Cyclopamine Conjugates.

D. Mazza, G. Damia, F. Ricci, 2017, ACS medicinal chemistry letters.

Synthesis and biological evaluation of imidazolo[2,1-b]benzothiazole derivatives, as potential p53 inhibitors.

F. Zunino, M. Christodoulou, D. Passarella, 2011, Bioorganic & medicinal chemistry.

Structure–Activity Relationships of Hexahydrocyclopenta[c]quinoline Derivatives as Allosteric Inhibitors of CDK2 and EGFR

L. Lo Presti, G. Rastelli, M. Broggini, 2018, ChemMedChem.

Tubulin-guided dynamic combinatorial library of thiocolchicine–podophyllotoxin conjugates

D. Passarella, J. Snaith, Stella Borrelli, 2011 .

Inhibitors of tubulin polymerization: synthesis and biological evaluation of hybrids of vindoline, anhydrovinblastine and vinorelbine with thiocolchicine, podophyllotoxin and baccatin III.

C. Ronchi, D. Passarella, G. Fontana, 2008, Bioorganic & medicinal chemistry.

Effect of chirality and lipophilicity in the functional activity of evodiamine and its analogues at TRPV1 channels

D. Passarella, G. Appendino, G. Fontana, 2014, British journal of pharmacology.

Can we use the epigenetic bioactivity of caloric restriction and phytochemicals to promote healthy ageing

M. Lahtela-Kakkonen, E. Bártová, M. Vidaković, 2014 .

Self-assembly drug conjugates for anticancer treatment.

M. Christodoulou, D. Passarella, F. Dosio, 2016, Drug discovery today.

Synthesis and biological evaluation of novel thiocolchicine-podophyllotoxin conjugates.

C. Ronchi, D. Passarella, G. Fontana, 2010, European journal of medicinal chemistry.

Design and Synthesis of New Withaferin A Inspired Hedgehog Pathway Inhibitors

L. Di Marcotullio, M. Mori, D. Passarella, 2021, Chemistry.

Click Reaction as a Tool to Combine Pharmacophores: The Case of Vismodegib.

M. Botta, M. Mori, G. Damia, 2015, ChemPlusChem.

Chiral Synthons via Enzyme-Mediated Asymmetrization of meso-Compounds

D. Passarella, S. Riva, B. Danieli, 1994 .

Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors

M. Bolognesi, R. Russo, L. Musso, 2020, Life.

Synthetic approach to imidazo[1,2-a]pyridine derivatives by the intramolecular nitrone cycloaddition methodology

D. Passarella, T. Pilati, A. Terraneo, 2002 .

Histone demethylating agents as potential S-adenosyl-L-methionine-competitors

M. Mori, G. Damia, R. Navakauskienė, 2016 .

Microtubule-targeting agents and neurodegeneration.

D. Passarella, Z. Boiarska, 2020, Drug discovery today.

New solution free and polymer anchored chiral bispidine-based amino alcohols. Synthesis and screening for the enantioselective addition of diethylzinc to benzaldehyde

D. Passarella, B. Danieli, A. Sacchetti, 2003 .

New flavonol glycosides from Aconitum burnatii Gáyer and Aconitum variegatum L.

D. Passarella, S. Vitalini, A. Braca, 2010, Fitoterapia.

Synthesis and biological evaluation of epothilone A dimeric compounds.

K. Altmann, D. Passarella, A. Quesada, 2009, Bioorganic & medicinal chemistry.

Self-assembled 4-(1,2-diphenylbut-1-en-1-yl)aniline based nanoparticles: podophyllotoxin and aloin as building blocks.

M. Christodoulou, D. Passarella, A. García-Argáez, 2017, Organic & biomolecular chemistry.

Synthesis, Antiproliferative E ﬀ ect, and Topoisomerase II Inhibitory Activity of 3 ‑ Methyl-2-phenyl ‑ 1 H ‑ indoles

D. Passarella, D. Secci, Nace Zidar, 2020 .

Farinose alpine Primula species: phytochemical and morphological investigations.

M. Christodoulou, D. Passarella, G. Flamini, 2014, Phytochemistry.

Enzymatic Kinetic Resolution of 2-Piperidineethanol for the Enantioselective Targeted and Diversity Oriented Synthesis

M. Christodoulou, D. Passarella, D. Perdicchia, 2015, International journal of molecular sciences.

Quantitative live cell imaging of a tauopathy model enables the identification of a polypharmacological drug candidate that restores physiological microtubule regulation

G. Rastelli, M. Christodoulou, D. Passarella, 2022, bioRxiv.

Stereocontrolled synthesis of enantiopure cis- and trans-3,4,4a,5,8,8a-hexahydro-1H-quinolin-2-ones

D. Passarella, J. Bosch, M. Amat, 2008 .

A Chemo-Enzymatic Approach to Some Indole and Quinolizidine Alkaloids From Cs -Symmetric Precursors

D. Passarella, B. Danieli, G. Lesma, 2000 .

Enzyme assisted enantioselective synthesis of the alkaloid (+)-aloperine

D. Passarella, S. Riva, B. Danieli, 2004 .

Synthesis and biological evaluation of new camptothecin derivatives obtained by modification of position 20.

J. Lorens, D. Passarella, O. Gia, 2010, Bioorganic & medicinal chemistry.

Studies on the Synthesis of Strychnos Alkaloids

D. Passarella, S. Sathyanarayana, J. Bosch, 1996 .

Enantiopure N-Boc piperidine-2-ethanol for the synthesis of (+)- and (−)-dumetorine, and (+)- and (−)-epidihydropinidine

D. Passarella, S. Riva, B. Danieli, 2009 .

Design, synthesis, biological evaluation and crystal structure determination of dual modulators of carbonic anhydrases and estrogen receptors.

G. Rastelli, J. Nwachukwu, K. Nettles, 2022, European journal of medicinal chemistry.

Catalytic C3 aza-alkylation of indoles.

D. Passarella, D. Perdicchia, Paola Marzullo, 2020, Organic & biomolecular chemistry.

Synthesis of Silodosin by Copper‐Catalysed C–C Arylation

P. Allegrini, D. Passarella, Emanuele Attolino, 2015 .

9-Fluorenone-2-Carboxylic Acid as a Scaffold for Tubulin Interacting Compounds.

S. Pieraccini, M. Sironi, D. Ballinari, 2013, ChemPlusChem.

Application of the Pd-catalyzed heteroarylation to the synthesis of 5-(indol-2′-yl)pyridin-2-one and 5-(indol-2′-yl)pyran-2-one

D. Passarella, B. Danieli, I. Peretto, 1998 .

Aspidosperma alkaloids cyclization of secodine intermediate: Synthesis of (±)-3-oxovincadifformine ethyl ester.

G. Palmisano, D. Passarella, B. Danieli, 1994 .

Identification of new aminoacid amides containing the imidazo[2,1-b]benzothiazol-2-ylphenyl moiety as inhibitors of tumorigenesis by oncogenic Met signaling.

A. Furlan, C. Tintori, M. Botta, 2012, European journal of medicinal chemistry.

Reaction of Grignard reagents with carbonyl compounds under continuous flow conditions

Daniele Vigo, Marisa Martinelli, Daniele Passarella, 2010 .

The 1,2,3-triazole ring as a bioisostere in medicinal chemistry.

G. Rastelli, M. Christodoulou, D. Passarella, 2017, Drug discovery today.

Concise total synthesis of (+/-)-aloperine and 6-epi-aloperine.

D. Passarella, B. Danieli, G. Lesma, 2002, Organic letters.

Intramolecular Cycloadditions of Nitrones Derived from 1-Allyl-2-pyrrolecarbaldehyde as a Route to Racemic and Enantiopure Pyrrolizidines and Indolizidines

D. Passarella, A. Arnone, G. Broggini, 1998 .

Double Michael Reaction of N-Carboethoxy-2,3-dihydropyridin-4-one

D. Passarella, G. Lesma, A. Silvani, 2001 .

Short enantioselective synthesis of sedridines, ethylnorlobelols and coniine via reagent-based differentiation

D. Passarella, S. Riva, B. Danieli, 2005 .

Synthetic studies on indole alxaloids. A stereocontrolled entry to the cuanzine structural unit

G. Palmisano, D. Passarella, B. Danieli, 1989 .

Quinazolinecarboline alkaloid evodiamine as scaffold for targeting topoisomerase I and sirtuins.

M. Lahtela-Kakkonen, F. Zunino, S. Pieraccini, 2013, Bioorganic & medicinal chemistry.

Chiral Amino-Amides as Solution Phase and Immobilized Ligands for the Catalytic Asymmetric Alkylation of Aromatic Aldehydes.

D. Passarella, B. Danieli, A. Sacchetti, 2006 .

Chiral Amino-Amides as Solution Phase and Immobilized Ligands for the Catalytic Asymmetric Alkylation of Aromatic Aldehydes

D. Passarella, B. Danieli, A. Sacchetti, 2006 .

Stereochemistry and complete 1H and 13C NMR signal assignment of C‐20‐oxime derivatives of posterone 2,3‐acetonide in solution state

D. Passarella, T. Gáti, G. Tóth, 2018, Magnetic resonance in chemistry : MRC.

Diels-Alder Reactions of Methyl N-p-Methoxybenzensulfonylindole-2-(2- propenoate), a Convenient Dienophile Towards the Synthesis of Andranginine.

D. Passarella, B. Danieli, G. Lesma, 1997 .

FIRST ENANTIOSELECTIVE SYNTHESIS OF (-)-AKAGERINE BY A CHEMOENZYMATIC APPROACH

G. Palmisano, D. Passarella, B. Danieli, 1995 .

A highly enantioselective synthesis of (−)-antirhine by chemo-enzymatic approach

G. Palmisano, D. Passarella, B. Danieli, 1994 .

An efficient chemo-enzymatic approach to (+)-meroquinene

G. Palmisano, D. Passarella, B. Danieli, 1990 .

Luciano De Petrocellis-CNS&ND-MS

L. Petrocellis, V. Marzo, D. Passarella, 2016 .

Boehmeriasin A as new lead compound for the inhibition of topoisomerases and SIRT2.

M. Lahtela-Kakkonen, M. Baumann, I. Baxendale, 2015, European journal of medicinal chemistry.

Synthesis and biological evaluation of pyrroloiminoquinone derivatives.

F. Zunino, D. Passarella, O. Gia, 2008, Bioorganic & medicinal chemistry.

Chiral diamines for asymmetric synthesis: an efficient RCM construction of the ligand core of (−)- and (+)-sparteine

D. Passarella, B. Danieli, A. Sacchetti, 2005 .

Structure-activity exploration of a small-molecule allosteric inhibitor of T790M/L858R double mutant EGFR

G. Rastelli, D. Passarella, L. Mologni, 2022, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and Biological Evaluation of Migrastatin Macrotriazoles

G. Rastelli, D. Passarella, P. Murphy, 2017 .

Studies on oxidation of ergot alkaloids: oxidation and desaturation of dihydrolysergol—stereochemical requirements

V. Křen, D. Passarella, B. Danieli, 2007 .

Enantiopure 2-piperidylacetaldehyde as a useful building block in the diversity-oriented synthesis of polycyclic piperidine derivatives

D. Passarella, S. Galli, S. Riva, 2011 .

Aspidosperma Alkaloids. Reaction of 3-Oxotabersonine with Nitrosonium Tetrafluoborate

D. Passarella, B. Danieli, G. Lesma, 1995 .

Exploiting enzymatic regioselectivity: a facile methodology for the synthesis of polyhydroxylated hybrid compounds.

D. Passarella, S. Riva, W. Panzeri, 2010, Organic & biomolecular chemistry.

Concise asymmetric synthesis of (−)-halosaline and (2R,9aR)-(+)-2-hydroxy-quinolizidine by ruthenium-catalyzed ring-rearrangement metathesis

D. Passarella, B. Danieli, A. Sacchetti, 2004 .

Biomimetic construction of the tetracyclic ring system of ngouniensine

D. Passarella, J. Bosch, N. Llor, 1999 .

Antiproliferative activity of yatein isolated from Austrocedrus chilensis against murine myeloma cells: Cytological studies and chemical investigations

D. Passarella, J. Becerra, A. Taddei, 2015, Pharmaceutical biology.

Thiocolchicine-podophyllotoxin conjugates: dynamic libraries based on disulfide exchange reaction.

F. Zunino, D. Passarella, B. Danieli, 2006, The Journal of organic chemistry.

Formal enantioselective synthesis of tacamonine starting from asymmetrized 2-substituted propane-1,3-diols

D. Passarella, B. Danieli, G. Lesma, 1999 .

Indole alkaloids by a chemoenzymatic approach: two convergent routes for the first enantioselective synthesis of (+)-20R-15,20-dihydrocleavamine

D. Passarella, B. Danieli, G. Lesma, 2000 .

An Efficient Enantioselective Entry to the Piperidino‐Quinolizidine Ring System of Lupine Alkaloids by Means of N‐Acyliminium Ion Initiated Cyclization Reactions

D. Passarella, B. Danieli, A. Consonni, 2001 .

trans-6-Aminocyclohept-3-enols, a new designed polyfunctionalized chiral building block for the asymmetric synthesis of 2-substituted-4-hydroxypiperidines.

D. Passarella, B. Danieli, A. Sacchetti, 2002, Organic letters.

Functionalization at C-17 of an Eburnea-Aspidosperma Binary Alkaloid as a Model to Study Modified Vinblastine-type Antitumor Alkaloids

G. Palmisano, D. Passarella, B. Danieli, 1994 .

Total enantioselective synthesis of (-)-cytisine.

D. Passarella, B. Danieli, A. Sacchetti, 2004, Organic letters.

'Click' synthesis of a triazole-based inhibitor of Met functions in cancer cells.

A. Furlan, C. Tintori, M. Botta, 2012, Bioorganic & medicinal chemistry letters.

Studies on the Laccase‐Catalyzed Oxidation of 4‐Hydroxy‐Chalcones

D. Monti, D. Passarella, S. Riva, 2019, Advanced Synthesis & Catalysis.

Synthesis of Thicolchicine-Based Conjugates: Investigation towards Bivalent Tubulin/Microtubules Binders.

S. Pieraccini, M. Sironi, M. Christodoulou, 2019, ChemPlusChem.

Frontiers in Natural Product Chemistry

C. Betzel, I. Fleming, M. Rajoka, 2009 .

Cyrene: A Green Solvent for the Synthesis of Bioactive Molecules and Functional Biomaterials

D. Passarella, N. Micale, A. Citarella, 2022, International journal of molecular sciences.

Remote stereocenter discrimination in the enzymatic resolution of piperidine-2-ethanol. Short enantioselective synthesis of sedamine and allosedamine.

D. Passarella, S. Riva, B. Danieli, 2003, The Journal of organic chemistry.

Covalent Nucleoside Adducts of Aspidosperma Alkaloids

G. Palmisano, D. Passarella, B. Danieli, 1991 .

Ibogaine analogues. Synthesis and preliminary pharmacological evaluation of 7-heteroaryl-2-azabicyclo[2.2.2]oct-7-enes.

D. Mash, D. Passarella, B. Danieli, 2003, Bioorganic & Medicinal Chemistry.

Vincamine by synthesis and semi-synthesis

D. Passarella, M. Luzzani, Francesca Foschi, 2020, Phytochemistry Reviews.

Vincamine by synthesis and semi-synthesis

D. Passarella, M. Luzzani, Francesca Foschi, 2020, Phytochemistry Reviews.

Nature-inspired indolyl-2-azabicyclo[2.2.2]oct-7-ene derivatives as promising agents for the attenuation of withdrawal symptoms: synthesis of 20-desethyl-20-hydroxymethyl-11-demethoxyibogaine

D. Passarella, B. Danieli, S. Efange, 2006, Natural product research.

Chemical approaches to targeting drug resistance in cancer stem cells.

M. Christodoulou, D. Passarella, P. Sotiropoulou, 2013, Drug discovery today.

Laccase-catalyzed coupling of catharanthine and vindoline: an efficient approach to the bisindole alkaloid anhydrovinblastine

D. Passarella, Cosimo Chirivì, G. Fontana, 2009 .

Vinblastine-Type Antitumor Alkaloids: A Method for Creating New C17 Modified Analogues

D. Passarella, B. Danieli, G. Lesma, 1998 .

Diastereoselective Synthesis of 3-Oxo-14,15-dihydroandranginine

D. Passarella, B. Danieli, G. Lesma, 1997 .

Indole Alkaloids by a Chemoenzymatic Approach: Two Convergent Routes for the First Enantioselective Synthesis of (+)-20R-15,20-dihydrocleavamine.

D. Passarella, B. Danieli, G. Lesma, 2000 .

Aspidosperma Alkaloids via Cyclization of Secodine Intermediate: Synthesis of (.+-.)-3-Oxovincadifformine Ethyl Ester.

G. Palmisano, D. Passarella, B. Danieli, 1994 .

Total Synthesis of (–)-Anaferine: A Further Ramification in a Diversity-Oriented Approach

D. Passarella, D. Perdicchia, Elisa Bonandi, 2020, Molecules.

Combined Drug Action of 2-Phenylimidazo[2,1-b]Benzothiazole Derivatives on Cancer Cells According to Their Oncogenic Molecular Signatures

A. Furlan, Fabrice Daian, D. Passarella, 2012, PloS one.

Camptothecin‐7‐yl‐methanthiole: Semisynthesis and Biological Evaluation

F. Zunino, S. Pieraccini, M. Sironi, 2012, ChemMedChem.

Synthesis, Antiproliferative Effect, and Topoisomerase II Inhibitory Activity of 3-Methyl-2-phenyl-1H-indoles.

D. Passarella, L. Dalla Via, D. Secci, 2020, ACS medicinal chemistry letters.

Imidazo[2,1-b]benzothiazol Derivatives as Potential Allosteric Inhibitors of the Glucocorticoid Receptor.

Benoît Y. Michel, S. Pieraccini, M. Sironi, 2018, ACS medicinal chemistry letters.

Engineered Ferritin Nanoparticles for the Bioluminescence Tracking of Nanodrug Delivery in Cancer.

M. Christodoulou, D. Passarella, M. Bellini, 2020, Small.

4-(1,2-diarylbut-1-en-1-yl)isobutyranilide derivatives as inhibitors of topoisomerase II.

L. Lo Presti, G. Damia, S. Pieraccini, 2016, European journal of medicinal chemistry.

Synthesis of Pironetin–Dumetorine Hybrids as Tubulin Binders

S. Pieraccini, M. Sironi, M. Christodoulou, 2016 .

Stimulus-responsive liposomes for biomedical applications.

P. Seneci, D. Passarella, S. Pellegrino, 2021, Drug discovery today.

Novel chemical probes for the investigation of nonribosomal peptide assembly.

D. Passarella, Elena Riva, M. Tosin, 2017, Chemical communications.

Dual Functionalized Liposomes for Selective Delivery of Poorly Soluble Drugs to Inflamed Brain Regions

P. Seneci, B. Vergani, G. Paglia, 2022, Pharmaceutics.

Convenient Preparation and Spectroscopic Characterization of 7R-Hydroxymatairesinol

D. Passarella, Eleonora Colombo, G. Paladino, 2021, Molecules.

Synthesis of potent and selective HDAC6 inhibitors led to unexpected opening of a quinazoline ring

G. Rastelli, D. Passarella, D. Moi, 2022, RSC advances.

AN ENANTIOSELECTIVE SYNTHESIS OF THE STRYCHNOS ALKALOID (-)-TUBIFOLINE

D. Passarella, J. Bosch, M. Coll, 1996 .

An efficient chemoenzymatic access to chiral 3,7-diazabicyclo[3.3.1]nonane derivatives

D. Passarella, B. Danieli, G. Lesma, 1999 .

Synthesis of enantiopure diamine ligands related to sparteine, via scandium triflate-catalyzed imino Diels–Alder reactions

D. Passarella, B. Danieli, A. Sacchetti, 2002 .

An Efficient Chemoenzymatic Access to Chiral 3,7‐Diazabicyclo[3.3.1]nonane Derivatives.

D. Passarella, B. Danieli, G. Lesma, 2000 .

Highly Enantiopure C1-Symmetric cis-Piperidine-3,5-dimethanol Monoacetates by Enzymatic Asymmetrization1

D. Passarella, B. Danieli, G. Lesma, 1998 .

Stereoselective enzymatic hydrolysis of dimethyl meso-piperidine-3,5-dicarboxylates

D. Passarella, B. Danieli, G. Lesma, 1996 .

Synthesis of Enantiopure Diamine Ligands Related to Sparteine, via Scandium Triflate‐Catalyzed Imino Diels—Alder Reactions.

D. Passarella, B. Danieli, A. Sacchetti, 2002 .

Highly Enantiopure C1‐Symmetric cis‐Piperidine‐3,5‐dimethanol Monoacetates by Enzymatic Asymmetrization.

D. Passarella, B. Danieli, G. Lesma, 1998 .

Stereoselective Enzymatic Hydrolysis of Dimethyl meso-Piperidine-3,5- dicarboxylates.

D. Passarella, B. Danieli, G. Lesma, 1996 .

AN EXPEDITIOUS SYNTHESIS OF DIMETHYL 1-BENZYL-CIS-PIPERIDINE-3,5-DICARBOXYLATE

D. Passarella, B. Danieli, G. Lesma, 1997 .

Expeditious Synthesis of Dimethyl 1-Benzyl-cis-piperidine-3,5- dicarboxylate.

D. Passarella, B. Danieli, G. Lesma, 1997 .

New class of squalene-based releasable nanoassemblies of paclitaxel, podophyllotoxin, camptothecin and epothilone A.

M. Zucchetti, G. Damia, F. Ricci, 2014, European journal of medicinal chemistry.

“Click” Synthesis of a Triazole‐Based Inhibitor of Met Functions in Cancer Cells.

D. Passarella, 2012 .

Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles

P. Seneci, D. Passarella, M. Colombo, 2022, RSC advances.

Cannabidiol as Self-Assembly Inducer for Anticancer Drug-Based Nanoparticles

D. Passarella, L. Dalla Via, M. D. Di Paolo, 2022, Molecules.

Tools for the rational design of bivalent microtubule-targeting drugs.

G. Tiana, M. Christodoulou, D. Passarella, 2016, Biochemical and biophysical research communications.

2-Hydroxyoleic Acid as a Self-Assembly Inducer for Anti-Cancer Drug-Centered Nanoparticles

P. Seneci, D. Passarella, L. Dalla Via, 2023, Pharmaceuticals.

Self-Assembly Nanoparticles of Natural Bioactive Abietane Diterpenes

L. Saraíva, D. Passarella, P. Rijo, 2021, International journal of molecular sciences.

New Class of Betulinic Acid-Based Nanoassemblies of Cabazitaxel, Podophyllotoxin, and Thiocolchicine.

D. Passarella, L. D. Via, L. Polito, 2020, ACS medicinal chemistry letters.

Self-assembling Releasable Thiocolchicine-Diphenylbutenylaniline Conjugates.

P. Seneci, M. Christodoulou, D. Passarella, 2019, ACS medicinal chemistry letters.

Cyclopamine-Paclitaxel-Containing Nanoparticles: Internalization in Cells Detected by Confocal and Super-Resolution Microscopy.

D. Mazza, G. Damia, F. Ricci, 2015, ChemPlusChem.

Self‐Assembled Squalene‐based Fluorescent Heteronanoparticles

M. Christodoulou, D. Passarella, P. Milla, 2015 .

A small library of chalcones induce liver cancer cell death through Akt phosphorylation inhibition

R. Cetin-Atalay, Ç. Karaca, M. Christodoulou, 2020, Scientific Reports.

Stereodivergent Diversity-Oriented Synthesis: Exploiting the Versatility of 2-Piperidine Ethanol

S. Pieraccini, M. Sironi, D. Passarella, 2019, European Journal of Organic Chemistry.

Promising Non-cytotoxic Monosubstituted Chalcones to Target Monoamine Oxidase-B

G. Rastelli, M. Christodoulou, D. Passarella, 2021, ACS medicinal chemistry letters.

Synthesis and Preliminary Characterization of Putative Anle138b-Centered PROTACs against α-Synuclein Aggregation

P. Seneci, V. Broccoli, D. Passarella, 2023, Pharmaceutics.

Dehydroroyleanone as a Building Block for a Drug Delivery Platform Based on Self-Assembled Nanoparticles: Structural Studies and Chemical Modification

D. Passarella, L. Ascensão, P. Rijo, 2022, ACS omega.

Dual targeted 2-Benzylideneindanone pendant hydroxamic acid group exhibits selective HDAC6 inhibition along with tubulin stabilization effect.

S. Srivastava, D. Chanda, D. Passarella, 2023, Bioorganic & medicinal chemistry.

CM1106 STEMCHEM : chemical approaches to targeting drug resistance cancer stem cells

D. Passarella, P. Schembri-Wismayer, A. Cassar, 2016 .

A Convenient Synthesis of Δ7,8-Morphinan-6-one and Its Direct Oxidation to 14-Hydroxy-Δ7,8-morphinan-6-one

D. Passarella, A. Consonni, G. Lesma, 2002 .

A Convenient Synthesis of Δ7,8-Morphinan-6-one and Its Direct Oxidation to 14-Hydroxy-Δ7,8-morphinan-6-one.

D. Passarella, A. Consonni, G. Lesma, 2002 .

Recent advances in the development of CB1R selective probes

A. Minassi, D. Passarella, V. Fasano, 2023, Frontiers in Natural Products.

Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders

K. Altmann, D. Lucena‐Agell, F. Vasile, 2021, Chemistry.

Natural Products and Cancer Stem Cells.

M. Christodoulou, D. Passarella, N. Martinet, 2015, Current pharmaceutical design.

Access to pyrrolo- and pyrido[1,2-a]indole derivatives by intramolecular nitrone cycloadditions. Effect of steric factors on the regioselective product formation.

D. Passarella, T. Pilati, C. La Rosa, 2000, The Journal of organic chemistry.

Access to Pyrrolo‐ and Pyrido[1,2‐a]indole Derivatives by Intramolecular Nitrone Cycloadditions. Effect of Steric Factors on the Regioselective Product Formation.

D. Passarella, T. Pilati, A. Terraneo, 2001 .

Probing the binding site of abl tyrosine kinase using in situ click chemistry.

C. Tintori, A. L. Fallacara, M. Botta, 2013, ACS medicinal chemistry letters.

Stereoselective Synthetic Strategies to (−)‐Cannabidiol

D. Passarella, V. Fasano, Alice Maiocchi, 2022, ChemistrySelect.

Total Synthesis of (‐)‐Cannabidiol‐C4

L. Lo Presti, D. Passarella, Paola Marzullo, 2022, European Journal of Organic Chemistry.

Tools for the rational design of bivalent microtubule-targeting drugs.

G. Tiana, M. Christodoulou, D. Passarella, 2016, Biochemical and biophysical research communications.

Identification of new aminoacid amides containing the imidazo[2,1-b]benzothiazol-2-ylphenyl moiety as inhibitors of tumorigenesis by oncogenic Met signaling.

A. Furlan, C. Tintori, M. Botta, 2012, European journal of medicinal chemistry.

Antiproliferative activity of yatein isolated from Austrocedrus chilensis against murine myeloma cells: Cytological studies and chemical investigations

D. Passarella, J. Becerra, A. Taddei, 2015, Pharmaceutical Biology.

First total synthesis of caerulomycin K: a case study on selective, multiple C–H functionalizations of pyridines

D. Passarella, Paolo Ronchi, Alessandro Dimasi, 2024, RSC Advances.

Late‐Stage Functionalisation of Pyridine‐Containing Bioactive Molecules: Recent Strategies and Perspectives

D. Passarella, V. Fasano, Daniele Fiorito, 2023, European Journal of Organic Chemistry.

Recent Advances in SARS-CoV-2 Main Protease Inhibitors: From Nirmatrelvir to Future Perspectives

D. Passarella, A. Scala, A. Piperno, 2023, Biomolecules.

Synthesis of SARS-CoV-2 Mpro inhibitors bearing a cinnamic ester warhead with in vitro activity against human coronaviruses.

S. Pieraccini, G. Gribaudo, D. Passarella, 2023, Organic & biomolecular chemistry.

New Tetracyclic Colchicinoids from the Reaction of N‐Deacetylthiocolchicine and N‐Deacetylcolchicine with Nitrous Acid and tert‐Butyl Nitrite

D. Passarella, D. Prosperi, B. Danieli, 2003 .

Cyclopamine-Paclitaxel-Containing Nanoparticles: Internalization in Cells Detected by Confocal and Super-Resolution Microscopy.

D. Mazza, G. Damia, F. Ricci, 2015, ChemPlusChem.