S. Dutta

发表

A Lipid-Modified Estrogen Derivative that Treats Breast Cancer Independent of Estrogen Receptor Expression through Simultaneous Induction of Autophagy and Apoptosis

D. Mukhopadhyay, P. Reddanna, S. Sinha, 2011, Molecular Cancer Research.

GAIP Interacting Protein C-Terminus Regulates Autophagy and Exosome Biogenesis of Pancreatic Cancer through Metabolic Pathways

D. Mukhopadhyay, S. Bhattacharya, T. Patel, 2014, PloS one.

Neuropilin-1 Mediates Divergent R-Smad Signaling and the Myofibroblast Phenotype*

D. Mukhopadhyay, V. Shah, R. Urrutia, 2010, The Journal of Biological Chemistry.

Von Hippel-Lindau Gene Product Modulates TIS11B Expression in Renal Cell Carcinoma

D. Mukhopadhyay, A. Ghosh, S. Sinha, 2009, The Journal of Biological Chemistry.

Plumbagin inhibits tumorigenesis and angiogenesis of ovarian cancer cells in vivo

D. Mukhopadhyay, F. Couch, S. Sinha, 2013, International journal of cancer.

VEGF neutralizing antibody increases the therapeutic efficacy of vinorelbine for renal cell carcinoma

D. Mukhopadhyay, S. Sinha, S. Dutta, 2008, Journal of cellular and molecular medicine.

Dopamine inhibits pulmonary edema through the VEGF-VEGFR2 axis in a murine model of acute lung injury.

Luke H. Hoeppner, D. Mukhopadhyay, S. Dutta, 2012, American journal of physiology. Lung cellular and molecular physiology.

Endogenous Vascular Endothelial Growth Factor-A (VEGF-A) Maintains Endothelial Cell Homeostasis by Regulating VEGF Receptor-2 Transcription*

D. Mukhopadhyay, S. Bhattacharya, S. Dutta, 2011, The Journal of Biological Chemistry.

Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP 1 / ATR-Mediated DNA Damage Response

D. Mukhopadhyay, A. Mazar, A. Kozikowski, 2019 .

Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR-Mediated DNA Damage Response

D. Mukhopadhyay, A. Mazar, A. Kozikowski, 2019, Clinical Cancer Research.

Insulin Receptor Substrate-2 Mediated Insulin-like Growth Factor-I Receptor Overexpression in Pancreatic Adenocarcinoma through Protein Kinase C D

D. Mukhopadhyay, S. Dutta, M. Muders, 2009 .

Insulin Receptor Substrate-2 Mediated Insulin-like Growth Factor-I Receptor Overexpression in Pancreatic Adenocarcinoma through Protein Kinase CD

D. Mukhopadhyay, S. Dutta, M. Muders, 2009 .

Molecular Inhibitor of QSOX1 Suppresses Tumor Growth In Vivo

D. Mukhopadhyay, D. Faigel, T. Ho, 2019, Molecular Cancer Therapeutics.

Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue

D. Mukhopadhyay, T. Smyrk, S. Chari, 2015, Gut.

Cardiomyopathy and Worsened Ischemic Heart Failure in SM22-&agr; Cre-Mediated Neuropilin-1 Null Mice: Dysregulation of PGC1&agr; and Mitochondrial Homeostasis

Luke H. Hoeppner, D. Mukhopadhyay, S. Bhattacharya, 2015, Arteriosclerosis, thrombosis, and vascular biology.

Protein kinase D up-regulates transcription of VEGF receptor-2 in endothelial cells by suppressing nuclear localization of the transcription factor AP2β

Luke H. Hoeppner, D. Mukhopadhyay, P. Storz, 2019, The Journal of Biological Chemistry.

Dissecting VEGF-induced acute versus chronic vascular hyperpermeability: Essential roles of dimethylarginine dimethylaminohydrolase-1

Luke H. Hoeppner, Tanmay Kulkarni, Alex Y Tam, 2020, iScience.

NHERF-2 maintains endothelial homeostasis.

D. Mukhopadhyay, Y. Prakash, S. Dutta, 2012, Blood.

VEGF exerts an angiogenesis-independent function in cancer cells to promote their malignant progression.

D. Mukhopadhyay, D. Bar-Sagi, Krishnendu Pal, 2012, Cancer research.

Development of multi-drug loaded PEGylated nanodiamonds to inhibit tumor growth and metastasis in genetically engineered mouse models of pancreatic cancer.

D. Mukhopadhyay, B. Fadeel, Krishnendu Pal, 2019, Nanoscale.

Expression and regulatory role of GAIP-interacting protein GIPC in pancreatic adenocarcinoma.

D. Mukhopadhyay, T. Smyrk, S. Chari, 2006, Cancer research.

Immunosuppressive CD14+HLA-DRlo/neg monocytes are elevated in pancreatic cancer and “primed” by tumor-derived exosomes

D. Mukhopadhyay, W. Bamlet, A. Dietz, 2017, Oncoimmunology.

Adrenomedullin is up-regulated in patients with pancreatic cancer and causes insulin resistance in β cells and mice.

D. Mukhopadhyay, W. Bamlet, Jing-jing Han, 2012, Gastroenterology.

Estrogen receptor alpha/beta isoforms, but not betacx, modulate unique patterns of gene expression and cell proliferation in Hs578T cells.

J. Ingle, S. Dutta, T. Spelsberg, 2007, Journal of cellular biochemistry.

Targeted delivery of gemcitabine to pancreatic adenocarcinoma using cetuximab as a targeting agent.

D. Mukhopadhyay, M. Yaszemski, J. Reid, 2008, Cancer research.

In vivo toxicity studies of europium hydroxide nanorods in mice.

D. Mukhopadhyay, V. Shah, S. Dutta, 2009, Toxicology and applied pharmacology.

Ablation of neuropilin-1 improves the therapeutic response in conventional drug-resistant glioblastoma multiforme

D. Mukhopadhyay, J. Sarkaria, S. Dutta, 2020, Oncogene.

Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth

D. Mukhopadhyay, Ruizhi Zhao, Krishnendu Pal, 2014, Molecular Cancer Therapeutics.

Inhibition of GSK-3 Induces Differentiation and Impaired Glucose Metabolism in Renal Cancer

D. Mukhopadhyay, S. Bhattacharya, A. Kozikowski, 2013, Molecular Cancer Therapeutics.

Pancreatic Cancer–Derived Exosomes Cause Paraneoplastic β-cell Dysfunction

D. Mukhopadhyay, S. Bhattacharya, G. Petersen, 2014, Clinical Cancer Research.

Neuropilin-1 Modulates p53/Caspases Axis to Promote Endothelial Cell Survival

D. Mukhopadhyay, S. Ekker, R. Khosravi‐Far, 2007, PloS one.

RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells

Luke H. Hoeppner, D. Mukhopadhyay, S. Ekker, 2015, Development.

Targeting GIPC/Synectin in Pancreatic Cancer Inhibits Tumor Growth

Ling Wang, Enfeng Wang, Adnan Memic, 2009, Clinical Cancer Research.

Design and Evaluation of PEGylated Liposomal Formulation of a Novel Multikinase Inhibitor for Enhanced Chemosensitivity and Inhibition of Metastatic Pancreatic Ductal Adenocarcinoma.

D. Mukhopadhyay, Y. Yen, Krishnendu Pal, 2019, Bioconjugate chemistry.

Von Hippel-Lindau gene product directs cytokinesis: a new tumor suppressor function

D. Mukhopadhyay, F. Couch, S. Sinha, 2011, Journal of Cell Science.

Targeted Dual Intervention-Oriented Drug-Encapsulated (DIODE) Nanoformulations for Improved Treatment of Pancreatic Cancer

D. Mukhopadhyay, Krishnendu Pal, S. Dutta, 2020, Cancers.

Designing Nanoconjugates to Effectively Target Pancreatic Cancer Cells In Vitro and In Vivo

Sheng Cao, Jameel Ahmad Khan, Enfeng Wang, 2011, PloS one.

Mutant BRAF Upregulates MCL-1 to Confer Apoptosis Resistance that Is Reversed by MCL-1 Antagonism and Cobimetinib in Colorectal Cancer

D. Mukhopadhyay, F. Sinicrope, Krishnendu Pal, 2016, Molecular Cancer Therapeutics.

Metformin Suppresses Pancreatic Tumor Growth With Inhibition of NF&kgr;B/STAT3 Inflammatory Signaling

D. Mukhopadhyay, W. Bamlet, A. Oberg, 2015, Pancreas.

Dopamine regulates phosphorylation of VEGF receptor 2 by engaging Src-homology-2-domain-containing protein tyrosine phosphatase 2

D. Mukhopadhyay, S. Sinha, S. Dutta, 2009, Journal of Cell Science.

Multifaceted peptide assisted one-pot synthesis of gold nanoparticles for plectin-1 targeted gemcitabine delivery in pancreatic cancer.

S. Bhattacharya, Krishnendu Pal, S. Dutta, 2017, Nanoscale.

RGS-GAIP–Interacting Protein Controls Breast Cancer Progression

D. Mukhopadhyay, S. Bhattacharya, S. Dutta, 2010, Molecular Cancer Research.

Role of PLEXIND1/TGFβ Signaling Axis in Pancreatic Ductal Adenocarcinoma Progression Correlates with the Mutational Status of KRAS

D. Mukhopadhyay, Y. Asmann, D. Chang, 2021, Cancers.

BRAFV600E-induced, tumor intrinsic PD-L1 can regulate chemotherapy-induced apoptosis in human colon cancer cells and in tumor xenografts

D. Mukhopadhyay, F. Sinicrope, Lei Sun, 2019, Oncogene.

Genetic status of KRAS modulates the role of Neuropilin-1 in tumorigenesis

D. Mukhopadhyay, S. Dutta, Ying Cao, 2017, Scientific Reports.

Synchronous inhibition of mTOR and VEGF/NRP1 axis impedes tumor growth and metastasis in renal cancer

D. Mukhopadhyay, Krishnendu Pal, S. Dutta, 2019, npj Precision Oncology.

The neurotransmitter dopamine modulates vascular permeability in the endothelium

D. Mukhopadhyay, S. Sinha, S. Dutta, 2008, Journal of molecular signaling.

Estrogen receptor α/β isoforms, but not βcx, modulate unique patterns of gene expression and cell proliferation in Hs578T cells

J. Ingle, S. Dutta, T. Spelsberg, 2007 .

LCC-09, a Novel Salicylanilide Derivative, Exerts Anti-Inflammatory Effect in Vascular Endothelial Cells

D. Mukhopadhyay, A. Wu, S. Dutta, 2021, Journal of inflammation research.

Glucocorticoid Receptor-Targeted Liposomal Codelivery of Lipophilic Drug and Anti-Hsp90 Gene: Strategy to Induce Drug-Sensitivity, EMT-Reversal, and Reduced Malignancy in Aggressive Tumors.

D. Mukhopadhyay, Krishnendu Pal, S. Dutta, 2016, Molecular pharmaceutics.

Protein Kinase C-Mediated Modulation of FIH-1 Expression by the Homeodomain Protein CDP/Cut/Cux

D. Mukhopadhyay, Shi-Wen Jiang, Jinping Li, 2007, Molecular and Cellular Biology.

Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer

D. Mukhopadhyay, Krishnendu Pal, S. Dutta, 2017, OncoTarget.

Small Molecule Therapeutics Inhibition of Endoglin – GIPC Interaction Inhibits Pancreatic Cancer Cell Growth

D. Mukhopadhyay, Ruizhi Zhao, Krishnendu Pal, 2014 .

DNA-SWCNT Biosensors allow real-time monitoring of therapeutic responses in Pancreatic Ductal Adenocarcinoma.

Freddy T. Nguyen, D. Mukhopadhyay, S. Bhattacharya, 2019, Cancer research.

Insulin receptor substrate-2 mediated insulin-like growth factor-I receptor overexpression in pancreatic adenocarcinoma through protein kinase Cdelta.

D. Mukhopadhyay, S. Dutta, M. Muders, 2009, Cancer research.

RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells

Luke H. Hoeppner, D. Mukhopadhyay, S. Ekker, 2015, Development.

Chemically modified peptides targeting the PDZ domain of GIPC as a therapeutic approach for cancer.

D. Mukhopadhyay, S. Bhattacharya, S. Dutta, 2012, ACS chemical biology.

[GIPC: a new target for therapy in pancreatic adenocarcinoma?].

D. Aust, G. Baretton, S. Dutta, 2007, Verhandlungen der Deutschen Gesellschaft fur Pathologie.

Co-delivery of everolimus and vinorelbine via a tumor-targeted liposomal formulation inhibits tumor growth and metastasis in RCC

D. Mukhopadhyay, S. Dutta, Krishnendu Pal, 2019, International journal of nanomedicine.

Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer.

D. Mukhopadhyay, Krishnendu Pal, S. Dutta, 2017, Oncotarget.

Genetic status of KRAS modulates the role of Neuropilin-1 in tumorigenesis

D. Mukhopadhyay, S. Dutta, Ying Cao, 2017, Scientific Reports.

Enriched pharmacokinetic behavior and antitumor efficacy of thymoquinone by liposomal delivery.

D. Mukhopadhyay, S. Bhattacharya, S. Dutta, 2021, Nanomedicine.

Targeting Gipc/synectin in Pancreatic Cancer Inhibits Tumor Growth Cancer Therapy: Preclinical Grant Support: Nih Grants Ca78383, Hl072178 and Hl70567, Mayo Clinic Pancreatic Cancer Spore Pilot Grant, Grant from the American Cancer Society

S. Dutta, E. Wang, P. Vohra, 2022 .

Von Hippel-Lindau gene product directs cytokinesis: a new tumor suppressor function

D. Mukhopadhyay, F. Couch, Seethalakshmi Iyer, 2011, Journal of Cell Science.

Adrenomedullin is up-regulated in patients with pancreatic cancer and causes insulin resistance in β cells and mice.

D. Mukhopadhyay, W. Bamlet, Jing-jing Han, 2012, Gastroenterology.

Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue

D. Mukhopadhyay, T. Smyrk, S. Chari, 2015, Gut.

RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells

Luke H. Hoeppner, D. Mukhopadhyay, S. Ekker, 2015, Journal of Cell Science.

Cardiomyopathy and Worsened Ischemic Heart Failure in SM22-&agr; Cre-Mediated Neuropilin-1 Null Mice: Dysregulation of PGC1&agr; and Mitochondrial Homeostasis

Luke H. Hoeppner, D. Mukhopadhyay, S. Bhattacharya, 2015, Arteriosclerosis, thrombosis, and vascular biology.

In vivo toxicity studies of europium hydroxide nanorods in mice.

D. Mukhopadhyay, V. Shah, S. Dutta, 2009, Toxicology and applied pharmacology.

The crosstalk between neuropilin-1 and tumor necrosis factor-α in endothelial cells

Luke H. Hoeppner, S. Dutta, S. Kilari, 2024, Frontiers in cell and developmental biology.

Conditional, Tissue-Specific CRISPR/Cas9 Vector System in Zebrafish Reveals the Role of Nrp1b in Heart Regeneration

D. Mukhopadhyay, Y. Wang, S. Dutta, 2023, Arteriosclerosis, thrombosis, and vascular biology.

Dual drug-loaded tumor-targeted polymeric nanoparticles for enhancing therapeutic response in pancreatic ductal adenocarcinoma

S. Bhattacharya, S. Dutta, A. V. S. Sainath, 2024, Materials today. Bio.

Targeting mTOR and survivin concurrently potentiates radiation therapy in renal cell carcinoma by suppressing DNA damage repair and amplifying mitotic catastrophe

S. Dutta, V. Madamsetty, R. S. Angom, 2024, Journal of experimental & clinical cancer research : CR.

Chemically-Modified Peptides Targeting the PDZ Domain of GIPC as a Therapeutic Approach for Cancer.

D. Mukhopadhyay, S. Bhattacharya, S. Dutta, 2015, ACS chemical biology.

Targeting GIPC/Synectin in Pancreatic Cancer Inhibits Tumor Growth

D. Mukhopadhyay, D. Aust, Adnan Memić, 2009, Clinical Cancer Research.