J. Schenkman

H. Popper, F. Hutterer, F. Schaffner, 1970, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Electrochemiluminescent arrays for cytochrome P450-activated genotoxicity screening. DNA damage from benzo[a]pyrene metabolites.

S. Krishnan, J. Schenkman, J. Rusling, 2007, Analytical chemistry.

Interactions between cytochrome P450 and cytochrome b5.

J. Schenkman, I. Jansson, 1999, Drug metabolism reviews.

The effects of albumin upon the spectral changes and metabolism by the hepatic microsomal fraction.

G. Powis, J. Schenkman, I. Jansson, 1977, Archives of biochemistry and biophysics.

Cytochrome P-450 alterations in the BB/Wor spontaneously diabetic rat.

J. Schenkman, L. Favreau, 1988, Biochemical pharmacology.

Metabolism of progesterone and estradiol by microsomes and purified cytochrome P-450 RLM3 and RLM5.

J. Schenkman, K. Cheng, 1984, Drug metabolism and disposition: the biological fate of chemicals.

Characterizing metabolic inhibition using electrochemical enzyme/DNA biosensors.

J. Schenkman, J. Rusling, B. Bajrami, 2009, Analytical chemistry.

Cytochrome P 450K of rat kidney cortex microsomes: its involvement in fatty acid - and ( -1)-hydroxylation.

S. Orrenius, J. Schenkman, A. Ellin, 1972, Archives of biochemistry and biophysics.

PRODUCTION OF MEMBRANE WHORLS IN RAT LIVER BY SOME INHIBITORS OF PROTEIN SYNTHESIS

K. M. Hwang, A. Sartorelli, J. Schenkman, 1974, The Journal of cell biology.

Hepatic organelle interaction. IV. Mechanism of succinate enhancement of formaldehyde accumulation from endoplasmic reticulum N-dealkylations

H. Denk, D. L. Cinti, S. Keyes, 1976, The Journal of cell biology.

Corrections - The Nature of the Reverse Type I (Modified Type II) Spectral Change in Liver Microsomes

S. Orrenius, D. L. Cinti, J. Schenkman, 1973 .

Newer aspects of substrate binding to cytochrome P-450.

S. Orrenius, D. L. Cinti, J. Schenkman, 1973, Drug metabolism and disposition: the biological fate of chemicals.

Induction of diabetes and evaluation of diabetic state on P450 expression.

J. Schenkman, 1991, Methods in enzymology.

Evaluation of electrochemiluminescent metabolic toxicity screening arrays using a multiple compound set.

Linlin Zhao, J. Schenkman, J. Rusling, 2011, Analytical Chemistry.

Genotoxicity screening for N-nitroso compounds. Electrochemical and electrochemiluminescent detection of human enzyme-generated DNA damage from N-nitrosopyrrolidine.

S. Krishnan, J. Schenkman, J. Rusling, 2007, Chemical communications.

The influence of phenobarbital on the turnover of hepatic microsomal cytochrome b5 and cytochrome P-450 hemes in the rat.

H. Greim, J. Schenkman, H. Remmer, 1970, Biochimica et biophysica acta.

A study of the interaction of a series of substituted barbituric acids with the hepatic microsomal monooxygenase.

S. Orrenius, J. Schenkman, L. Ernster, 1972, Archives of biochemistry and biophysics.

Monoclonal antibodies to rat liver cytochrome P-450 2c/RLM5 that regiospecifically inhibit steroid metabolism.

D. Waxman, J. Schenkman, H. Gelboin, 1989, Biochemical pharmacology.

The cytochrome P-450-containing mono-oxygenase system of rat kidney cortex microsomes.

S. Orrenius, R. Estabrook, D. L. Cinti, 1973, Drug metabolism and disposition: the biological fate of chemicals.

Active oxygen in liver microsomes: mechanism of epinephrine oxidation.

G. Powis, J. Schenkman, H. Kappus, 1979, Molecular pharmacology.

The effect of microsomal fatty acids and other lipids on the spin state of partially purified cytochrome P-450.

S. Sligar, D. L. Cinti, J. Schenkman, 1980, The Journal of biological chemistry.

Toxicity screening by electrochemical detection of DNA damage by metabolites generated in situ in ultrathin DNA-enzyme films.

J. D. Stuart, J. Schenkman, J. Rusling, 2003, Journal of the American Chemical Society.

The many roles of cytochrome b5.

J. Schenkman, I. Jansson, 2003, Pharmacology & therapeutics.

4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone, a second-generation antineoplastic agent of the alpha-(N)-heterocyclic carboxaldehyde thiosemicarbazone series.

I. Wodinsky, A. Sartorelli, J. Schenkman, 1977, Cancer research.

Substrate interaction with cytochrome P-450.

S. Sligar, D. L. Cinti, S. Sligar, 1981, Pharmacology & therapeutics.

Spectral studies of drug interaction with hepatic microsomal cytochrome.

R. Estabrook, J. Schenkman, J B Schenkman, 1967, Molecular pharmacology.

Preparation of microsomes with calcium.

D. L. Cinti, J. Schenkman, 1978, Methods in enzymology.

Studies on three microsomal electron transfer enzyme systems. Specificity of electron flow pathways.

J. Schenkman, I. Jansson, 1977, Archives of biochemistry and biophysics.

On the use of nicotinamide in assays for microsomal mixed-function oxidase activity.

R. Estabrook, J. Schenkman, J. Ball, 1967, Biochemical pharmacology.

Alteration of hepatic microsomal enzymes by griseofulvin treatment of mice.

J. Schenkman, R. Talcott, R. Eckerstorfer, 1977, Biochemical pharmacology.

Molecular Aspects of Monooxygenases and Bioactivation of Toxic Compounds

J. Schenkman, E. Hodgson, E. Arınç, 1991, NATO ASI Series Advanced Science Institutes Series.

Interaction between microsomal electron transfer pathways.

J. Schenkman, I. Jansson, 1975, Advances in experimental medicine and biology.

Cholate solubilization of liver microsomal membrane components which promote NADPH-supported lipid peroxidation.

J. Schenkman, H. Davis, Y. Tampo, 1992, Archives of biochemistry and biophysics.

Kinetics of hepatic cytochrome P-450 reduction: correlation with spin state of the ferric heme.

S. Sligar, J. Schenkman, W. Backes, 1982, Biochemistry.

Possible mechanism of coupled NADPH oxidase and P-450 monooxygenase action.

J. Schenkman, I. Jansson, 1981, Advances in experimental medicine and biology.

Influences of substrates of different microsomal electron transfer pathways on the oxidation-reduction kinetics of microsomal cytochrome b5.

J. Schenkman, I. Jansson, 1978, Archives of biochemistry and biophysics.

Evidence against participation of cytochrome b5 in the hepatic microsomal mixed-function oxidase reaction.

J. Schenkman, I. Jansson, 1973, Molecular pharmacology.

Kinetic parameters of drug-metabolizing enzymes in Ca 2+ -sedimented microsomes from rat liver.

D. L. Cinti, J. Schenkman, P. Moldéus, 1972, Biochemical pharmacology.

Immunochemical studies on the role of reduced nicotinamide adenine dinucleotide phosphate-cytochrome c (P-450) reductase in drug oxidation.

R. Glazer, A. Sartorelli, J. Schenkman, 1971, Molecular pharmacology.

The rate-limiting step in aminopyrine demethylase of rat liver microsomes.

D. L. Cinti, J. Schenkman, 1970, Biochemical pharmacology.

The relationship between the pH-induced spectral change in ferriprotoheme and the substrate-induced spectral change of the hepatic microsomal mixed-function oxidase.

J. Schenkman, R. Sato, 1968, Molecular pharmacology.

The effects of temperature and substrates on component reactions of the hepatic microsomal mixed-function oxidase.

J. Schenkman, 1972, Molecular pharmacology.

Hepatic organelle interaction. 3. Mitochondrial modification of microsomal drug metabolism.

D. L. Cinti, J. Schenkman, P. Moldéus, 1973, The Journal of biological chemistry.

The nature of the reverse type I (modified type II) spectral change in liver microsomes.

S. Orrenius, D. L. Cinti, J. Schenkman, 1972, Biochemistry.

Mechanism of cholestasis: III. Interaction of synthetic detergents with the microsomal cytochrome P-450 dependent biotransformation system in vitro A comparison between the effects of detergents, the effects of bile acids, and the findings in bile duct ligated rats

H. Denk, H. Popper, F. Hutterer, 1971 .

Studies on the nature of the type I and type II spectral changes in liver microsomes.

J. Schenkman, 1970, Biochemistry.

EPR measurements of substrate interaction with cytochrome P-450.

R. Estabrook, J. Schenkman, W. Cammer, 1966, Biochemical and biophysical research communications.

Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.

J. Schenkman, D. Choudhary, M. Sarfarazi, 2003, Archives of biochemistry and biophysics.

Regioselective hydroxylation of prostaglandins by constitutive forms of cytochrome P-450 from rat liver: formation of a novel metabolite by a female-specific P-450.

J. Schenkman, L. Favreau, I. Jansson, 1988, Archives of biochemistry and biophysics.

The significance of drug-induced spectral changes in liver microsomal fraction.

S. Orrenius, J. Schenkman, C. von Bahr, 1971, The Biochemical journal.

Kinetics of cytochrome P-450 reduction: evidence for faster reduction of the high-spin ferric state.

S. Sligar, J. Schenkman, G. Gibson, 1985, Biochemistry.

Temperature-dependent spin equilibrium of microsomal and solubilized cytochrome P-450 from rat liver.

S. Sligar, D. L. Cinti, J. Schenkman, 1979, Biochemistry.

SPECTRAL INVESTIGATIONS ON CYTOCHROME-P-450

H. Greim, J. Schenkman, H. Remmer, 1969 .

On the problem of possible other forms of cytochrome P450 in liver microsomes.

H. Greim, J. Schenkman, H. Remmer, 1969, Biochimica et biophysica acta.

Effect of phenobarbital and 3,4-benzpyrene treatment of rats on the microsomal binding and hydroxylation of nortriptyline and desmethyl-imipramine: evidence for qualitative changes in cytochrome P-450-ligand interaction following phenobarbital pretreatment.

S. Orrenius, J. Schenkman, C. von Bahr, 1972, Xenobiotica; the fate of foreign compounds in biological systems.

Human cyt P450 mediated metabolic toxicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) evaluated using electrochemiluminescent arrays.

S. Krishnan, J. Schenkman, J. Rusling, 2009, Molecular bioSystems.

THE MITOCHONDRIAL ROLE IN HEPATIC CELL MIXED‐FUNCTION OXIDATIONS *

D. L. Cinti, J. Schenkman, P. Moldéus, 1973, Annals of the New York Academy of Sciences.

Elucidating organ-specific metabolic toxicity chemistry from electrochemiluminescent enzyme/DNA arrays and bioreactor bead-LC-MS/MS

Dhanuka P Wasalathanthri, J. Schenkman, J. Rusling, 2015, Chemical science.

Metabolic action of urethan on protein synthesis and drug oxidation in normal and regenerating liver.

R. Glazer, D. L. Cinti, A. Sartorelli, 1972, Biochemical pharmacology.

Fingerprinting rat liver microsomal cytochromes P-450 as a means of delineating sexually distinctive forms

J. Schenkman, L. Favreau, D. Kreutzer, 2004, Archives of Toxicology.

Spectral analyses of cytochromes P450.

J. Schenkman, I. Jansson, 2006, Methods in molecular biology.

Dimethylaminoethyl 2,2-diphenylvalerate HCl (SKF 525-A)--in vivo and in vitro effects of metabolism by rat liver microsomes--formation of an oxygenated complex.

D. L. Cinti, J. Schenkman, B. J. Wilson, 1972, Biochemical pharmacology.

Hepatic mixed function oxidase activity in rapidly prepared microsomes

D. L. Cinti, J. Schenkman, 1972 .

Inhibition of nadph-driven microsomal lipid peroxidation by cytosol factor(s). Effect of a fat-free, high carbohydrate diet.

J. Schenkman, R. Talcott, R. Eckerstorfer, 1976, Chemico-biological interactions.

Roles of Cytochrome P450 in Development

J. Schenkman, M. Sarfarazi, I. Stoilov,, 2001, Drug metabolism and drug interactions.

Genetics and biochemistry of primary congenital glaucoma.

J. Schenkman, M. Sarfarazi, I. Stoilov, 2003, Ophthalmology clinics of North America.

Accurate DNA fragment sizing by capillary electrophoresis with laser-induced fluorescence array for detection of sequence specificity of DNA damage.

J. Schenkman, J. Rusling, D. Choudhary, 2008, Analytical chemistry.

Physiological Significance and Expression of P450s in the Developing Eye

J. Schenkman, D. Choudhary, M. Sarfarazi, 2006, Drug metabolism reviews.

Introduction to Cytochrome P450

J. Schenkman, I. Jansson, 1995 .

Reductive metabolism of halothane by purified cytochrome P-450.

J. Schenkman, R. V. Van dyke, I. Jansson, 1988, Biochemical pharmacology.

Inverse relationship between cytochrome P-450 phosphorylation and complexation with cytochrome b5.

J. Schenkman, P. Epstein, I. Jansson, 1987, Archives of biochemistry and biophysics.

Mechanism of interaction between cytochromes P-450 RLM5 and b5: evidence for an electrostatic mechanism involving cytochrome b5 heme propionate groups.

J. Schenkman, P. Tamburini, 1986, Archives of biochemistry and biophysics.

Chemical selectivity of nucleobase adduction relative to in vivo mutation sites on exon 7 fragment of p53 tumor suppressor gene

J. Schenkman, J. Rusling, K. Kadimisetty, 2015, Chemical science.

Testosterone metabolism by cytochrome P-450 isozymes RLM3 and RLM5 and by microsomes. Metabolite identification.

J. Schenkman, K. Cheng, J B Schenkman, 1983, The Journal of biological chemistry.

[109] Methods for the elevation of hepatic microsomal mixed function oxidase levels and cytochrome P-450

R. Estabrook, H. Greim, J. Schenkman, 1967 .

CYP1B1, a developmental gene with a potential role in glaucoma therapy

J. Schenkman, D. Choudhary, I. Jansson, 2009, Xenobiotica; the fate of foreign compounds in biological systems.

Roles of CYP1B1, Optineurin, and WDR36 Gene Mutations in Glaucoma

J. Schenkman, D. Choudhary, S. Monemi, 2008 .

Hepatic microsomal mixed function oxidase.

J. Schenkman, 1970, Science.

Screening for Reactive Metabolites Using Genotoxicity Arrays and Enzyme/DNA Biocolloids

J. Schenkman, J. Rusling, Eli G. Hvastkovs, 2010 .

Epoxidation of styrene by human cyt P450 1A2 by thin film electrolysis and peroxide activation compared to solution reactions.

James F Rusling, J. Schenkman, J. Rusling, 2003, Biophysical chemistry.

Microsomal biotransformation system in cholestasis.

H. Greim, F. Hutterer, J. Schenkman, 1972, Progress in liver diseases.

Chemical characterization of protein-protein interactions between cytochrome P-450 and cytochrome b5.

J. Schenkman, P. Tamburini, R. White, 1985, The Journal of biological chemistry.

Interaction Between Cytochrome P450 and Reductase

J. Schenkman, A. Voznesensky, 1995 .

KINETIC AND SPECTRAL EVIDENCE FOR MULTIPLE SPECIES OF CYTOCHROME P-450 IN LIVER MICROSOMES

G. Powis, J. Schenkman, R. Talcott, 1977 .

Effect of two mutations of human CYP1B1, G61E and R469W, on stability and endogenous steroid substrate metabolism.

J. Schenkman, M. Sarfarazi, I. Jansson, 2001, Pharmacogenetics.

Metabolic toxicity screening using electrochemiluminescence arrays coupled with enzyme-DNA biocolloid reactors and liquid chromatography-mass spectrometry.

J. Schenkman, J. Rusling, Eli G. Hvastkovs, 2012, Annual review of analytical chemistry.

Biochemical properties of rat liver mitochondrial aldehyde dehydrogenase with respect to oxidation of formaldehyde.

H. Denk, D. L. Cinti, S. Keyes, 1976, The Journal of biological chemistry.

Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues.

J. Schenkman, D. Choudhary, M. Sarfarazi, 2005, Archives of biochemistry and biophysics.

Hepatic organelle interaction. II. Effect of tricarboxylic acid cycle intermediates on N-demethylation and hydroxylation reactions in rat liver.

D. L. Cinti, J. Schenkman, A. Ritchie, 1972, Molecular pharmacology.

Spin state control of the hepatic cytochrome P450 redox potential.

S. Sligar, D. L. Cinti, J. Schenkman, 1979, Biochemical and biophysical research communications.

The role of the mitochondria in rat liver mixed function oxidation reactions.

D. L. Cinti, J. Schenkman, P. Moldéus, 1972, Biochemical and biophysical research communications.

The contribution of the microsomal electron transport pathway to the oxidative metabolism of liver.

R. Estabrook, J. Schenkman, A. Shigematsu, 1970, Advances in enzyme regulation.

Reduction kinetics of purified rat liver cytochrome P-450. Evidence for a sequential reaction mechanism dependent on the hemoprotein spin state.

S. Sligar, J. Schenkman, G. Gibson, 1984, Biochemistry.

Dissection of cytochrome P-450 isozymes (RLM) from fractions of untreated rat liver microsomal proteins.

J. Schenkman, K. Cheng, W. Backes, 1982, Biochemical and biophysical research communications.

THE ROLES OF MEMBRANE AND SUBSTRATES IN THE MODULATION OF CYTOCHROME P-450 FUNCTION

S. Sligar, D. L. Cinti, J. Schenkman, 1980 .

Linlin Zhao, J. Schenkman, J. Rusling, 2013, Chemical research in toxicology.

High‐Throughput Enzyme Biocolloid Systems for Drug Metabolism and Genotoxicity Profiling Using LC–MS/MS

J. Schenkman, J. Rusling, 2013 .

Screening reactive metabolites bioactivated by multiple enzyme pathways using a multiplexed microfluidic system.

James F Rusling, Dhanuka P Wasalathanthri, Spundana Malla, 2013, The Analyst.

Thin multicomponent films for functional enzyme devices and bioreactor particles.

Dhanuka P Wasalathanthri, J. Schenkman, J. Rusling, 2014, Soft matter.

Control of electrochemical and ferryloxy formation kinetics of cyt P450s in polyion films by heme iron spin state and secondary structure.

James F Rusling, S. Krishnan, J. Schenkman, 2009, Journal of the American Chemical Society.

Expression of cytochrome P4501b1 (Cyp1b1) during early murine development.

J. Schenkman, T. Rezaie, M. Sarfarazi, 2004, Molecular Vision.

Electrochemical biosensor featuring a two-enzyme pathway and DNA for screening toxic reactive metabolites of arylamines.

J. Schenkman, J. Rusling, Minjeong So, 2008, Chemical communications.

Charge-dependent sidedness of cytochrome P450 forms studied by quartz crystal microbalance and atomic force microscopy.

J. Schenkman, J. Rusling, Y. Lvov, 2001, Archives of biochemistry and biophysics.

Cytochrome P450-Dependent Monooxygenase: An Overview

J. Schenkman, 1991 .

Functional Aspects of Protein-Protein Interactions of Cytochrome P450 Cytochrome b5 and Cytochrome P450 Reductase

J. Schenkman, 1991 .

Age and sex differences in constitutive forms of cytochrome P-450 of rat liver microsomes.

J. Schenkman, L. Favreau, I. Jansson, 1986, Advances in experimental medicine and biology.

Selective stimulation by urethan of hepatic microsomal aniline hydroxylation.

A. Sartorelli, J. Schenkman, Y. Cha, 1974, Biochemical pharmacology.

Calorimetric study of microsomal membrane.

G. Powis, J. Schenkman, S. Mabrey, 1977, Journal of Biological Chemistry.

Purification and properties of cytochrome P-450 obtained from liver microsomes of untreated rats by lauric acid affinity chromatography.

J. Schenkman, G. Gibson, 1978, The Journal of biological chemistry.

Bioelectronic delivery of electrons to cytochrome P450 enzymes.

S. Krishnan, J. Schenkman, J. Rusling, 2011, The journal of physical chemistry. B.

Direct Electrochemistry of Cytochrome P450 Reductases in Surfactant and Polyion Films

J. Schenkman, J. Rusling, N. Sultana, 2007 .

Direct Electrochemistry of Myoglobin and Cytochrome P450cam in Alternate Layer-by-Layer Films with DNA and Other Polyions

James F. Rusling, Yuri Lvov, J. Schenkman, 1998 .

Composition Changes in Hepatic Microsomal Cytochrome P-450 During Onset of Streptozocin-Induced Diabetes and During Insulin Treatment

J. Schenkman, L. Favreau, Leonard V Favreau, 1988, Diabetes.

SPIN STATES AND REDOX POTENTIALS OF HEPATIC CYTOCHROME P450

S. Sligar, J. Schenkman, G. Gibson, 1980 .

α-Glycerophosphate Dehydrogenase Activity in Rat Spermatozoa

J. Schenkman, W. W. Westerfeld, D. Richert, 1965 .

Mechanism of cholestasis. 2. Effect of bile acids on the microsomal electron transfer system in vitro.

H. Denk, H. Popper, F. Hutterer, 1970, Life sciences. Pt. 2: Biochemistry, general and molecular biology.

Phosphorylation of cytochrome P450: regulation by cytochrome b5.

J. Schenkman, P. Epstein, C. Huang, 1989, Archives of biochemistry and biophysics.

Molecular Aspects of Oxidative Drug Metabolizing Enzymes

J. Schenkman, E. Hodgson, E. Arınç, 1995, NATO ASI Series.

The cytochrome P450 2B4-NADPH cytochrome P450 reductase electron transfer complex is not formed by charge-pairing.

J. Schenkman, A. Voznesensky, 1992, The Journal of biological chemistry.

Differences in the mechanism of functional interaction between NADPH-cytochrome P-450 reductase and its redox partners.

J. Schenkman, P. Tamburini, 1986, Molecular pharmacology.

Optimization of Electrochemical and Peroxide‐Driven Oxidation of Styrene with Ultrathin Polyion Films Containing Cytochrome P450cam and Myoglobin

James F Rusling, J. Schenkman, J. Rusling, 2003, Chembiochem : a European journal of chemical biology.

Electrochemical genotoxicity screening for arylamines bioactivated by N-acetyltransferase.

J. Schenkman, J. Rusling, Eli G. Hvastkovs, 2008, Analytical chemistry.

Evidence of binary complex formations between cytochrome P-450, cytochrome b5, and NADPH-cytochrome P-450 reductase of hepatic microsomes.

J. Schenkman, P. Tamburini, S. MacFarquhar, 1986, Biochemical and biophysical research communications.

Toxicity screening using biosensors that measure DNA damage.

J. Schenkman, J. Rusling, Eli G. Hvastkovs, 2007, Current opinion in drug discovery & development.

Steroid metabolism by constitutive cytochromes P450

J. Schenkman, 1992, The Journal of Steroid Biochemistry and Molecular Biology.

AN ANTITHYROTOXIC ASSAY BASED UPON THE RESPONSE OF RAT LIVER ALPHA-GLYCEROPHOSPHATE DEHYDROGENASE.

J. Schenkman, W. W. Westerfeld, D. Richert, 1964, The Journal of nutrition.

Aryl Hydrocarbon Hydroxylase: Induction

J. Schenkman, I. Jansson, K. Robie, 1977 .

Inhibition of cytochrome-P450 reductase by polyols has an electrostatic nature.

J. Schenkman, A. Voznesensky, 1992, European journal of biochemistry.

Differences in the spectral interactions between NADPH-cytochrome P-450 reductase and a series of cytochrome P-450 enzymes.

J. Schenkman, L. Favreau, W. Backes, 1986, Biochemical and biophysical research communications.

INFLUENCE OF SUBSTRATES OF HEPATIC MIXED FUNCTION OXIDASES ON SPIN EQUILIBRIUM OF CYTOCHROME P-450

S. Sligar, D. L. Cinti, J. Schenkman, 1980 .

Evaluating enzymes that generate genotoxic benzo[a]pyrene metabolites using sensor arrays.

J. Schenkman, J. Rusling, I. Jansson, 2005, Analytical Chemistry.

The NH2-terminal region of rabbit CYP2E1 is not essential for interaction with NADPH-cytochrome P450 reductase.

M. J. Coon, J. Schenkman, A. Voznesensky, 1994, Biochemical and biophysical research communications.