Zhuo Chen

发表

Challenges for drug discovery - a case study of urokinase receptor inhibition.

Mingdong Huang, Zhuo Chen, Lin Lin, 2009, Combinatorial chemistry & high throughput screening.

A Strategy of NIR Dual‐Excitation Upconversion for Ratiometric Intracellular Detection

Zhuo Chen, Xueyuan Chen, Renfu Li, 2019, Advanced science.

Broadband NIR photostimulated luminescence nanoprobes based on CaS:Eu2+,Sm3+ nanocrystals

Zhuo Chen, Xueyuan Chen, Renfu Li, 2019, Chemical science.

Graphene‐Oxide‐Modified Lanthanide Nanoprobes for Tumor‐Targeted Visible/NIR‐II Luminescence Imaging

Zhuo Chen, Huanghao Yang, Datao Tu, 2019, Angewandte Chemie.

Nanoparticle Binding to Urokinase Receptor on Cancer Cell Surface Triggers Nanoparticle Disintegration and Cargo Release

Wenlie Chen, C. Yuan, Mingdong Huang, 2019, Theranostics.

Time-resolved luminescent biosensing based on inorganic lanthanide-doped nanoprobes.

Ping Huang, Zhuo Chen, Datao Tu, 2015, Chemical communications.

Photodynamic Oncotherapy Mediated by Gonadotropin-Releasing Hormone Receptors.

Mingdong Huang, Zhuo Chen, Ping Hu, 2017, Journal of medicinal chemistry.

Phthalocyanine-Biomolecule Conjugated Photosensitizers for Targeted Photodynamic Therapy and Imaging.

Z. Iqbal, Mingdong Huang, Zhuo Chen, 2015, Current drug metabolism.

Outstanding drug loading capacity by water stable microporous MOF: a potential drug carrier.

Zhuo Chen, R. Cao, P. Bag, 2016, Chemical communications.

Household light source for potent photo-dynamic antimicrobial effect and wound healing in an infective animal model.

Z. Iqbal, Mingdong Huang, Zhuo Chen, 2018, Biomedical optics express.

Sub-5 nm lanthanide-doped lutetium oxyfluoride nanoprobes for ultrasensitive detection of prostate specific antigen† †Electronic supplementary information (ESI) available: ESI, Tables S1–S4, Fig. S1–S20 and Movie S1. See DOI: 10.1039/c5sc04599a

Mingdong Huang, Zhuo Chen, Ping Huang, 2016, Chemical science.

In vitro upconverting/downshifting luminescent detection of tumor markers based on Eu3+-activated core–shell–shell lanthanide nanoprobes† †Electronic supplementary information (ESI) available: Materials & methods, Fig. S1–S17 and Tables S1–S2. See DOI: 10.1039/c6sc01195k

Zhuo Chen, M. Hong, Yongsheng Liu, 2016, Chemical science.

Embelin ameliorated sepsis-induced disseminated intravascular coagulation intensities by simultaneously suppressing inflammation and thrombosis.

W. Hong, Mingdong Huang, Zhuo Chen, 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Multiplexed intracellular detection based on dual-excitation/dual-emission upconversion nanoprobes

Zhuo Chen, Datao Tu, Xueyuan Chen, 2020, Nano Research.

A novel purification procedure for recombinant human serum albumin expressed in Pichia pastoris.

C. Yuan, Mingdong Huang, Zhuo Chen, 2018, Protein expression and purification.

An efficient synergistic cancer therapy by integrating cell cycle inhibitor and photosensitizer into polydopamine nanoparticles.

Mingdong Huang, Zhuo Chen, Xueyuan Chen, 2018, Journal of materials chemistry. B.

Synergistic Lysozyme‐Photodynamic Therapy Against Resistant Bacteria based on an Intelligent Upconversion Nanoplatform

Zhuo Chen, Xueyuan Chen, Renfu Li, 2021, Angewandte Chemie.

Synergistic lysozyme-photodynamic therapy against resistant bacteria based on an intelligent upconversion nanoplatform.

Zhuo Chen, Xueyuan Chen, Renfu Li, 2021, Angewandte Chemie.

Zinc phthalocyanine conjugated with the amino-terminal fragment of urokinase for tumor-targeting photodynamic therapy.

Yunmei Huang, Mingdong Huang, Zhuo Chen, 2014, Acta biomaterialia.

An advanced multifunctional prodrug combining photodynamic therapy with chemotherapy for highly efficient and precise tumor ablation

Mingdong Huang, Zhuo Chen, Ping Hu, 2022, Dyes and Pigments.

A strategy for enhanced tumor targeting of photodynamic therapy based on Escherichia coli-driven drug delivery system

Jian-Qiang Su, Yunmei Huang, Mingdong Huang, 2020, Science China Materials.

Rapid killing of bacteria by a new type of photosensitizer

Z. Iqbal, Mingdong Huang, Zhuo Chen, 2017, Applied Microbiology and Biotechnology.

Substituted zinc phthalocyanine as an antimicrobial photosensitizer for periodontitis treatment

Mingdong Huang, Fuhua Yan, Zhuo Chen, 2011 .

Dissolution-enhanced luminescent bioassay based on inorganic lanthanide nanoparticles.

Mingdong Huang, Zhuo Chen, Yongsheng Liu, 2014, Angewandte Chemie.

tPA Point Mutation at Autolysis Loop Enhances Resistance to PAI-1 Inhibition and Catalytic Activity

C. Yuan, Mingdong Huang, Zhuo Chen, 2018, Thrombosis and Haemostasis.

Receptor-Targeting Phthalocyanine Photosensitizer for Improving Antitumor Photocytotoxicity

Mingdong Huang, Zhuo Chen, Ping Hu, 2012, PloS one.

Mn2+-activated calcium fluoride nanoprobes for time-resolved photoluminescence biosensing

Zhuo Chen, Ping Huang, Xueyuan Chen, 2018, Science China Materials.

Time‐Resolved Luminescent Biosensing Based on Inorganic Lanthanide‐Doped Nanoprobes

Ping Huang, Zhuo Chen, Datao Tu, 2015 .

A new class of luminescent nanoprobes based on main-group Sb3+ emitters

Zhuo Chen, Ping Huang, Xueyuan Chen, 2021, Nano Research.

Broadband excitable NIR-II luminescent nano-bioprobes based on CuInSe2 quantum dots for the detection of circulating tumor cells

Zhuo Chen, Ping Hu, Chen Xueyuan, 2020 .

Multifunctional Nano-Bioprobes Based on Rattle-Structured Upconverting Luminescent Nanoparticles.

M. Wang, Mingdong Huang, Zhuo Chen, 2015, Angewandte Chemie.

A drug carrier targeting murine uPAR for photodynamic therapy and tumor imaging.

C. Yuan, Mingdong Huang, Zhuo Chen, 2015, Acta biomaterialia.

Lanthanide-doped LaOBr nanocrystals: controlled synthesis, optical spectroscopy and bioimaging.

Zhuo Chen, Ping Hu, Datao Tu, 2017, Journal of materials chemistry. B.

A nanometer-sized protease inhibitor for precise cancer diagnosis and treatment.

W. Hong, Mingdong Huang, Xu-zheng Chen, 2019, Journal of materials chemistry. B.

Near-infrared-excited upconversion photodynamic therapy of extensively drug-resistant Acinetobacter baumannii based on lanthanide nanoparticles.

Yunmei Huang, Zhuo Chen, Xueyuan Chen, 2020, Nanoscale.

Composite of silver nanoparticles and photosensitizer leads to mutual enhancement of antimicrobial efficacy and promotes wound healing

Mingdong Huang, Zhuo Chen, Di Zhang, 2019, Chemical Engineering Journal.

Effects of hydroxyl radicals produced by a zinc phthalocyanine photosensitizer on tumor DNA

Mingdong Huang, Zhuo Chen, Jincan Chen, 2020 .

Rechargeable and LED-activated ZnGa2O4 : Cr3+ near-infrared persistent luminescence nanoprobes for background-free biodetection.

Ping Huang, Zhuo Chen, Jianlin Shi, 2017, Nanoscale.

Lanthanide-doped LiLuF(4) upconversion nanoprobes for the detection of disease biomarkers.

Ping Huang, En Ma, Shanyong Zhou, 2014, Angewandte Chemie.

Inorganic lanthanide nanoprobes for background-free luminescent bioassays

Ping Huang, Zhuo Chen, Datao Tu, 2015, Science China Materials.

Lanthanide-doped NaScF4 nanoprobes: crystal structure, optical spectroscopy and biodetection.

Yu Ai, Mingdong Huang, Ping Hu, 2013, Nanoscale.

An effective zinc phthalocyanine derivative against multidrug-resistant bacterial infection

Mingdong Huang, Zhuo Chen, Ping Hu, 2017 .

Dual antimicrobial actions on modified fabric leads to inactivation of drug-resistant bacteria

W. Weijie, Z. Iqbal, Mingdong Huang, 2017 .

Near-infrared-triggered antibacterial and antifungal photodynamic therapy based on lanthanide-doped upconversion nanoparticles.

Mingdong Huang, Zhuo Chen, Ping Hu, 2018, Nanoscale.

13 Tumor-specific imaging and photodynamic therapy targeting the urokinase receptor

Z. Iqbal, C. Yuan, Mingdong Huang, 2017 .

Expression, purification and characterization of recombinant Jerdonitin, a P-II class snake venom metalloproteinase comprising metalloproteinase and disintegrin domains.

C. Yuan, Mingdong Huang, Zhuo Chen, 2010, Toxicon : official journal of the International Society on Toxinology.

Dual actions of albumin packaging and tumor targeting enhance the antitumor efficacy and reduce the cardiotoxicity of doxorubicin in vivo

Yunmei Huang, Mingdong Huang, Zhuo Chen, 2015, International journal of nanomedicine.

Structural basis for therapeutic intervention of uPA/uPAR system.

C. Yuan, Mingdong Huang, Zhuo Chen, 2011, Current drug targets.

Be Active or Not: the Relative Contribution of Active and Passive Tumor Targeting of Nanomaterials

C. Yuan, Mingdong Huang, Zhuo Chen, 2017, Nanotheranostics.

A Novel Tumor Targeting Drug Carrier for Optical Imaging and Therapy

Wei Zheng, En Ma, Shanyong Zhou, 2014, Theranostics.

Plasminogen activator inhibitor (PAI) trap3, an exocellular peptide inhibitor of PAI-1, attenuates the rearrangement of F-actin and migration of cancer cells.

Mingdong Huang, Zhe-Sheng Chen, Zhuo Chen, 2020, Experimental cell research.

Specific inhibition of plasminogen activator inhibitor 1 reduces blood glucose level by lowering TNF-α.

Mingdong Huang, Zhuo Chen, X. Pan, 2020, Life sciences.

Lanthanide-doped luminescent nano-bioprobes for the detection of tumor markers.

Shanyong Zhou, Mingdong Huang, Ping Huang, 2015, Nanoscale.

Graphene Oxide Modified Lanthanide Nanoprobes for Tumor-Targeted Visible/NIR-II Luminescence Imaging.

Zhuo Chen, Huanghao Yang, Datao Tu, 2019, Angewandte Chemie.

Direct Detection of Circulating Tumor Cells in Whole Blood Based on Time-Resolved Luminescent Lanthanide Nanoprobes.

Zhuo Chen, Xueyuan Chen, Wen Lei, 2019, Angewandte Chemie.

Lanthanide-doped upconversion nanoparticles electrostatically coupled with photosensitizers for near-infrared-triggered photodynamic therapy.

Meng Wang, En Ma, Shanyong Zhou, 2014, Nanoscale.

Amine-functionalized lanthanide-doped KGdF4 nanocrystals as potential optical/magnetic multimodal bioprobes.

Mingdong Huang, Renfu Li, Jincan Chen, 2012, Journal of the American Chemical Society.

Suppression of Cancer Proliferation and Metastasis by a Versatile Nanomedicine Integrating Photodynamic therapy, Photothermal therapy, and Enzyme Inhibition.

W. Hong, Mingdong Huang, Zhuo Chen, 2020, Acta biomaterialia.

Suppression of Cancer Proliferation and Metastasis by a Versatile Nanomedicine Integrating Multiple Therapeutic Mechanisms

Mingdong Huang, Zhuo Chen, Ping Hu, 2020 .

Amine-functionalized lanthanide-doped zirconia nanoparticles: optical spectroscopy, time-resolved fluorescence resonance energy transfer biodetection, and targeted imaging.

En Ma, Shanyong Zhou, Mingdong Huang, 2012, Journal of the American Chemical Society.

Sub-10 nm lanthanide-doped CaF2 nanoprobes for time-resolved luminescent biodetection.

Wei Zheng, Shanyong Zhou, Mingdong Huang, 2013, Angewandte Chemie.

Albumin-based nanoparticles combined with photodynamic therapy enhance the antitumor activity of curcumin derivative C086

Yunmei Huang, Zhuo Chen, Ping Hu, 2021 .

Enhanced antitumor efficacy and imaging application of photosensitizer-formulated Paclitaxel.

C. Yuan, Mingdong Huang, Zhuo Chen, 2020, ACS applied materials & interfaces.

A long-acting PAI-1 inhibitor reduces thrombus formation

L. Yao, B. Furie, C. Yuan, 2017, Thrombosis and Haemostasis.

Lanthanide Upconversion Nanoplatforms for Advanced Bacteria‐Targeted Detection and Therapy

Zhuo Chen, Xueyuan Chen, Shan Lu, 2023, Advanced Optical Materials.

An effective zinc phthalocyanine derivative for photodynamic antimicrobial chemotherapy

Shanyong Zhou, Mingdong Huang, Ping Hu, 2014 .

Pentalysine β‐Carbonylphthalocyanine Zinc: An Effective Tumor‐Targeting Photosensitizer for Photodynamic Therapy

Shanyong Zhou, Mingdong Huang, Michael R Hamblin, 2010, ChemMedChem.

Direct Detection of Circulating Tumor Cells in Whole Blood Using Time‐Resolved Luminescent Lanthanide Nanoprobes

Zhuo Chen, Xueyuan Chen, Hanhan Guo, 2019, Angewandte Chemie.

AIEgen-sensitized lanthanide nanocrystals as luminescent probes for intracellular Fe3+ monitoring.

F. Liu, Zhuo Chen, Ping Hu, 2023, Talanta.

Phthalocyanine-based photosensitizer with tumor-pH-responsive properties for cancer theranostics.

Mingdong Huang, Zhuo Chen, Ping Hu, 2018, Journal of materials chemistry. B.

A new class of nitrobenzoic acid-based AIE photosensitizers for highly efficient photodynamic antibacterial therapy

Zhuo Chen, Xueyuan Chen, X. Pan, 2021, Science China Materials.

The binding mechanism of a peptidic cyclic serine protease inhibitor.

C. Weydert, H. P. Sørensen, N. Nielsen, 2011, Journal of molecular biology.

Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides.

Mingdong Huang, Zhuo Chen, P. Andreasen, 2019, Journal of medicinal chemistry.

Targeting the autolysis loop of urokinase-type plasminogen activator with conformation-specific monoclonal antibodies.

K. Mortensen, Mingdong Huang, Zhuo Chen, 2011, The Biochemical journal.

Enhancing Dye-Triplet-Sensitized Upconversion Emission Through Heavy Atom Effect in CsLu2F7:Yb/Er Nanoprobes.

Zhuo Chen, Datao Tu, Xueyuan Chen, 2021, Angewandte Chemie.

Monomer and Oligomer Transition of Zinc Phthalocyanine Is Key for Photobleaching in Photodynamic Therapy

C. Yuan, Mingdong Huang, Zhuo Chen, 2023, Molecules.

Dissociation of zinc phthalocyanine aggregation on bacterial surface is key for photodynamic antimicrobial effect

C. Yuan, Mingdong Huang, Zhuo Chen, 2018, Journal of Porphyrins and Phthalocyanines.

A series of photosensitizers with incremental positive electric charges for photodynamic antitumor therapy

Mingdong Huang, Zhuo Chen, Xiaorong Song, 2019, RSC advances.

Photodynamic antimicrobial chemotherapy using zinc phthalocyanine derivatives in treatment of bacterial skin infection

Dong Wang, Linsen Li, Yaxin Zhang, 2016, Journal of biomedical optics.

A Serum-Stable supramolecular drug carrier for chemotherapeutics fabricated by a Peptide-Photosensitizer conjugate.

Yunmei Huang, Mingdong Huang, Zhuo Chen, 2023, Journal of colloid and interface science.

Smart Photosensitizer: Tumor-Triggered Oncotherapy by Self-Assembly Photodynamic Nanodots.

Mingdong Huang, Zhuo Chen, Ping Hu, 2018, ACS applied materials & interfaces.

Naftifine enhances photodynamic therapy against Staphylococcus aureus by inhibiting staphyloxanthin expression

Jing Sun, Mingdong Huang, Zhuo Chen, 2020 .