A. Sappino

发表

Functional evaluation of plasmin formation in primary breast cancer.

P. Chappuis, H. Bonnefoi, B. Dieterich, 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

The plasminogen activator/plasmin system.

D. Belin, A. Sappino, J. Vassalli, 1991, The Journal of clinical investigation.

Set-up of a population-based familial breast cancer registry in Geneva, Switzerland: validation of first results.

G. Vlastos, H. Verkooijen, P. Chappuis, 2004, Annals of oncology : official journal of the European Society for Medical Oncology.

Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis

Martine A. Collart, A. Sappino, P. Vassalli, 1990, Nature.

Impact of familial risk factors on management and survival of early-onset breast cancer: a population-based study

G. Vlastos, H. Verkooijen, P. Chappuis, 2005, British Journal of Cancer.

Plasminogen activators in tissue remodeling and invasion: mRNA localization in mouse ovaries and implanting embryos

D. Belin, A. Sappino, J. Vassalli, 1989, The Journal of cell biology.

The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection

V. Kindler, A. Sappino, P. Vassalli, 1989, Cell.

Malignant glioma: should chemotherapy be overthrown by experimental treatments?

N. de Tribolet, A. Sappino, P. Dietrich, 1998, Annals of oncology : official journal of the European Society for Medical Oncology.

PCR-mediated detection of a polymorphism in the ATM gene.

P. Chappuis, A. Sappino, P. Maillet, 1999, Molecular and cellular probes.

Socio-demographic predictors of high support needs in newly diagnosed breast cancer patients.

G. Vlastos, A. Sappino, G. Haller, 2011, European journal of cancer care.

Extracellular proteolysis in the adult murine brain.

D. Belin, J. Kiss, A. Sappino, 1993, The Journal of clinical investigation.

Spontaneous regression of angiosarcoma

S. Ely, A. Sappino, R. Bartolotta, 2019, Cancer Archives.

Coronary spasm induced by capecitabine.

B. Schnetzler, A. Sappino, N. Popova, 2001, Annals of oncology : official journal of the European Society for Medical Oncology.

Effects of oral clodronate on bone mineral density in patients with relapsing breast cancer.

R. Rizzoli, M. Forni, D. Slosman, 1996, Bone.

Protease‐nexin I as an androgen‐dependent secretory product of the murine seminal vesicle.

D. Belin, A. Velardi, A. Sappino, 1993, The EMBO journal.

Sites of synthesis of urokinase and tissue-type plasminogen activators in the murine kidney.

D. Belin, A. Sappino, J. Vassalli, 1991, The Journal of clinical investigation.

Use of Conservative Surgery for Stage I Breast Cancer Falls Dramatically for Women Aged 80 and Older

G. Vlastos, A. Sappino, G. Fioretta, 2003, Journal of the American Geriatrics Society.

Increased risk of acute myeloid leukaemia after treatment for breast cancer.

G. Vlastos, H. Verkooijen, A. Sappino, 2006, Breast.

Increase of urokinase-type plasminogen activator gene expression in human lung and breast carcinomas.

D. Belin, A. Sappino, J. Vassalli, 1987, Cancer research.

Elevated levels of angiogenic cytokines in the plasma of cancer patients

L. Rubbia‐Brandt, A. Sappino, M. Pepper, 2000, International journal of cancer.

Adjuvant chemotherapy for colon carcinoma with positive lymph nodes: use and benefit in routine health care practice

M. Usel, M. Zellweger, A. Sappino, 2001, British Journal of Cancer.

Colonic pericryptal fibroblasts

G. Gabbiani, A. Sappino, P. Dietrich, 1989, Virchows Archiv A.

Increased risk of malignant mullerian tumor of the uterus among women with breast cancer treated by tamoxifen.

G. Vlastos, H. Verkooijen, A. Sappino, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Expression of alpha-smooth-muscle actin in stromal cells of the uterine cervix during epithelial neoplastic changes.

G. Gabbiani, M. Cintorino, S. Tripodi, 1991, International journal of cancer.

Tumor necrosis factor/cachectin and lymphotoxin gene expression in lymph nodes from lymphoma patients.

A. Sappino, P. Vassalli, M. Pelte, 1990, Blood.

Locally applied GM-CSF induces the accumulation of α-smooth muscle act in containing myofibroblasts

L. Rubbia‐Brandt, G. Gabbiani, A. Sappino, 1991, Virchows Archiv. B, Cell pathology including molecular pathology.

Regulation of parathyroid hormone-related protein production in a human lung squamous cell carcinoma line.

R. Rizzoli, A. Sappino, G. Grau, 1994, The Journal of endocrinology.

Aluminum Enters Mammalian Cells and Destabilizes Chromosome Structure and Number

S. Mandriota, A. Sappino, C. Green, 2021, International journal of molecular sciences.

Parathyroid hormone‐related protein and hypercalcemia in pancreatic neuro‐endocrine tumors

R. Rizzoli, A. Sappino, J. Bonjour, 1990, International journal of cancer.

Plasminogen activator inhibitor‐1 is induced in migrating endothelial cells

L. Orci, R. Montesano, A. Sappino, 1992, Journal of cellular physiology.

Pediatric Medulloblastoma: Prognostic Value of p53, bcl-2, Mib-1, and Microvessel Density

R. Miralbell, A. Probst, A. Sappino, 2004, Journal of Neuro-Oncology.

Genomic Instability Is an Early Event in Aluminium-Induced Tumorigenesis

M. Tenan, S. Mandriota, A. Sappino, 2020, International journal of molecular sciences.

Tubular up-regulation of clusterin mRNA in murine lupus-like nephritis.

L. French, A. Sappino, S. Moll, 1998, The American journal of pathology.

Percutaneous cementoplasty in multiple myeloma: a valuable adjunct for pain control and ambulation maintenance

A. Sappino, Jean-Baptiste Martin, D. Rufenacht, 2008, Supportive Care in Cancer.

Differential protease expression by cutaneous squamous and basal cell carcinomas.

J. Saurat, D. Belin, A. Sappino, 1991, The Journal of clinical investigation.

Ataxia Telangiectasia Mutated (ATM) Inhibition Transforms Human Mammary Gland Epithelial Cells*

F. Béna, C. Rüegg, R. Montesano, 2010, Journal of Biological Chemistry.

Distinct sites of production and deposition of the putative cell death marker clusterin in the human thymus.

L. French, A. Sappino, J. Tschopp, 1992, The Journal of clinical investigation.

Protease nexin 1 in the murine kidney: glomerular localization and up-regulation in glomerulopathies.

A. Sappino, J. Vassalli, N. Schaeren-Wiemers, 1996, Kidney international.

Swiss primary care physicians' knowledge, attitudes and perception towards genetic testing for hereditary breast cancer

M. Zwahlen, R. Stahel, A. Sappino, 2004, Familial Cancer.

Plasminogen activator and mouse spermatozoa: urokinase synthesis in the male genital tract and binding of the enzyme to the sperm cell surface

D. Belin, A. Sappino, J. Vassalli, 1987, The Journal of cell biology.

Plasminogen activator inhibitor-1 in acute hyperoxic mouse lung injury.

D. Belin, A. Sappino, J. Vassalli, 1996, The Journal of clinical investigation.

Induction of plasminogen activator inhibitor type 1 in murine lupus-like glomerulonephritis.

A. Sappino, J. Vassalli, S. Moll, 1995, Kidney international.

Monoclonal antibody LICR-LON-E36 recognizes gonadotrophs in female rat pituitaries.

M. A. Knight, A. Sappino, P. Monaghan, 1984, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

A polymorphism in the ATM gene modulates the penetrance of hereditary non‐polyposis colorectal cancer

P. Chappuis, P. Hutter, A. Sappino, 2000, International journal of cancer.

LPS induces major changes in the extracellular proteolytic balance in the murine kidney.

J. Schifferli, A. Sappino, J. Vassalli, 1994, Kidney international.

Smooth muscle differentiation in scleroderma fibroblastic cells.

J. Saurat, G. Gabbiani, A. Sappino, 1990, The American journal of pathology.

Infusional ECarboF in patients with advanced breast cancer: a very active and well-tolerated out-patient regimen.

H. Bonnefoi, A. Sappino, J. Anguenot, 2000, Annals of oncology : official journal of the European Society for Medical Oncology.

Plasminogen activation in human acute leukaemias

A. Sappino, J. Vassalli, E. Kruithof, 1999, British journal of haematology.

Plasminogen activation in melanocytic neoplasia: 328

J. Saurat, A. Sappino, J. Vassalli, 1993 .

The PA‐Plasmin System during Murine Embryogenesis

D. Belin, A. Sappino, A. Wohlwend, 1992, Annals of the New York Academy of Sciences.

Aluminium chloride promotes tumorigenesis and metastasis in normal murine mammary gland epithelial cells

M. Tenan, S. Mandriota, A. Sappino, 2016, International journal of cancer.

Plasminogen activators in the mouse mammary gland. Decreased expression during lactation.

D. Belin, A. Sappino, J. Vassalli, 1989, The Journal of biological chemistry.

Cyclic AMP increases the release of parathyroid hormone‐related protein from a lung‐cancer cell line

A. Sappino, M. Aubert, J. Bonjour, 1994, International journal of cancer.

The Kidney Is a Major Site of a 2-Antiplasmin Production

A. Sappino, J. Vassalli, P. Menoud, 2013 .

The kidney is a major site of alpha(2)-antiplasmin production.

A. Sappino, J. Vassalli, P. Menoud, 1996, The Journal of clinical investigation.

Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulations.

W. Schürch, G. Gabbiani, A. Sappino, 1990, Laboratory investigation; a journal of technical methods and pathology.

A simple p53 functional assay for screening cell lines, blood, and tumors.

P. Chappuis, J. Benhattar, A. Sappino, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Patients’ Refusal of Surgery Strongly Impairs Breast Cancer Survival

G. Vlastos, H. Verkooijen, H. Bonnefoi, 2005, Annals of surgery.

Repression of the putative tumor suppressor gene Bard1 or expression of Notch4(int-3) oncogene subvert the morphogenetic properties of mammary epithelial cells.

I. Irminger-Finger, R. Montesano, A. Sappino, 2000, Advances in experimental medicine and biology.

Twenty-three novel BRCA1 and BRCA2 sequence variations identified in a cohort of Swiss breast and ovarian cancer families.

P. Chappuis, V. Sciretta, A. Sappino, 2006, Cancer genetics and cytogenetics.

Primary care physicians' knowledge and attitudes towards genetic testing for breast-ovarian cancer predisposition.

M. Escher, A. Sappino, André-Pascal Sappino, 2000, Annals of oncology : official journal of the European Society for Medical Oncology.

Expression of α‐sooth‐muscle actin in stromal cells of the uterine cervix during epithlial neoplastic changes

G. Gabbiani, M. Cintorino, S. Tripodi, 1991 .

Smooth‐muscle differentiation in stromal cells of malignant and non‐malignant breast tissues

W. Schürch, G. Gabbiani, A. Sappino, 1988, International journal of cancer.

Detection of ATM gene deletion/duplication by multiplex ligation-dependant probe amplification in childhood lymphoid malignancies: a report from the Children's Oncology Group.

F. Gumy-Pause, A. Sappino, D. Betts, 2008, Leukemia research.

Complete excision of primary breast tumor improves survival of patients with metastatic breast cancer at diagnosis.

G. Vlastos, H. Verkooijen, P. Chappuis, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A role for atm in E-cadherin-mediated contact inhibition in epithelial cells

L. Vutskits, R. Montesano, A. Sappino, 2006, Breast Cancer Research and Treatment.

Prognostic significance of p53 mutation in breast cancer: Frequent detection of non‐missense mutations by yeast functional assay

P. Chappuis, H. Bonnefoi, R. Iggo, 1999, International journal of cancer.

ATM promoter analysis in childhood lymphoid malignancies: a brief communication.

F. Gumy-Pause, A. Sappino, D. Betts, 2006, Leukemia research.

If exposure to aluminium in antiperspirants presents health risks, its content should be reduced.

B. Fauconneau, A. Sappino, A. Pineau, 2014, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

Aluminium chloride promotes anchorage‐independent growth in human mammary epithelial cells

S. Gimelli, F. Béna, D. Belin, 2012, Journal of applied toxicology : JAT.

The exon 13 duplication in the BRCA1 gene is a founder mutation present in geographically diverse populations. The BRCA1 Exon 13 Duplication Screening Group.

M. Beckmann, T. Sellers, M. Stratton, 2000, American journal of human genetics.

Upregulation of urokinase receptor expression on migrating endothelial cells

L. Orci, R. Montesano, R. Stöcklin, 1993, The Journal of cell biology.

Effect of gamma-interferon on the clinical and biologic evolution of hypertrophic scars and Dupuytren's disease: an open pilot study.

A. Desmoulière, G. Gabbiani, A. Sappino, 1994, Plastic and reconstructive surgery.

Plasminogen activation in synovial tissues: differences between normal, osteoarthritis, and rheumatoid arthritis joints

A. Sappino, N. Busso, V. Péclat, 1997, Annals of the rheumatic diseases.

GSTP1 hypermethylation is associated with reduced protein expression, aggressive disease and prognosis in neuroblastoma

A. Gayet-Ageron, E. Attiyeh, F. Gumy-Pause, 2012, Genes, chromosomes & cancer.

Plasminogen activation in melanocytic neoplasia.

J. Saurat, A. Sappino, J. Vassalli, 1994, Cancer research.

The CEACAM1 tumor suppressor is an ATM and p53-regulated gene required for the induction of cellular senescence by DNA damage

W. Reith, S. Mandriota, F. Gumy-Pause, 2012, Oncogenesis.

ATM gene and lymphoid malignancies

F. Gumy-Pause, A. Sappino, P. Wacker, 2004, Leukemia.

ATM alterations in childhood non-Hodgkin lymphoma.

F. Gumy-Pause, A. Sappino, D. Betts, 2006, Cancer genetics and cytogenetics.

Important increase of invasive lobular breast cancer incidence in Geneva, Switzerland

G. Vlastos, H. Verkooijen, A. Sappino, 2003, International journal of cancer.

Undertreatment strongly decreases prognosis of breast cancer in elderly women.

G. Vlastos, P. Laissue, A. Sappino, 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

In Vitro Repression of Brca1-associated RING Domain Gene, Bard1, Induces Phenotypic Changes in Mammary Epithelial Cells

I. Irminger-Finger, R. Montesano, A. Sappino, 1998, The Journal of cell biology.

Survival of young and older breast cancer patients in Geneva from 1990 to 2001.

G. Vlastos, H. Verkooijen, A. Sappino, 2005, European journal of cancer.

Tumor Location of the Lower-Inner Quadrant Is Associated with an Impaired Survival for Women With Early-Stage Breast Cancer

G. Vlastos, H. Verkooijen, A. Sappino, 2007, Annals of Surgical Oncology.

Human clusterin gene expression is confined to surviving cells during in vitro programmed cell death.

L. French, J. Schifferli, A. Sappino, 1994, The Journal of clinical investigation.

Trend of burnout among Swiss doctors.

A. Sappino, F. Arigoni, P. Bovier, 2010, Swiss medical weekly.

Prevalence of burnout among Swiss cancer clinicians, paediatricians and general practitioners: who are most at risk?

A. Sappino, F. Arigoni, P. Bovier, 2008, Supportive Care in Cancer.

ATM variants and predisposition to childhood T-lineage acute lymphoblastic leukaemia

F. Gumy-Pause, A. Sappino, D. Betts, 2006, Leukemia.

In Vitro Repression of Brca 1-associated RING Domain Gene , Bard 1 , Induces Phenotypic Changes in Mammary Epithelial Cells

I. Irminger-Finger, R. Montesano, A. Sappino, 1998 .

Constitutional alterations of the ATM gene in early onset sporadic breast cancer

P. Chappuis, W. Foulkes, H. Bonnefoi, 2002, Journal of medical genetics.

Constitutional alterations of the ATM gene in early-onset sporadic breast cancer

H. Bonnefoi, A. Sappino, P. Maillet, 2000, Breast Cancer Research.

Management of women with ductal carcinoma in situ of the breast: a population-based study.

C. de Wolf, G. Vlastos, H. Verkooijen, 2002, Annals of oncology : official journal of the European Society for Medical Oncology.

Plasmin-catalyzed proteolysis in colorectal neoplasia.

A. Sappino, J. Vassalli, C. Delbaldo, 1995, Cancer research.

Prognosis of breast cancer in young women: a population-based study

G. Vlastos, H. Verkooijen, A. Sappino, 2004 .

Survival after bilateral breast cancer: results from a population-based study

G. Vlastos, H. Verkooijen, P. Chappuis, 2007, Breast Cancer Research and Treatment.

[Complementary medicine use in oncology patients].

A. Sappino, F. Arigoni, C. Burton-Jeangros, 2008, Revue medicale suisse.

Recent increase of breast cancer incidence among women under the age of forty

G. Vlastos, H. Verkooijen, P. Chappuis, 2007, British Journal of Cancer.

Modulation of hepatocyte growth factor and c-met in the rat mammary gland during pregnancy, lactation, and involution.

L. Orci, R. Montesano, A. Sappino, 1995, Experimental cell research.

Long-term survival five years or more after combination chemotherapy and radiotherapy for small cell lung carcinoma.

I. Smith, A. Sappino, P. Bondy, 1981, European journal of cancer & clinical oncology.

Breast-conserving surgery has equivalent effect as mastectomy on stage I breast cancer prognosis only when followed by radiotherapy.

G. Vlastos, A. Sappino, G. Fioretta, 2003, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Murine clusterin: molecular cloning and mRNA localization of a gene associated with epithelial differentiation processes during embryogenesis

L. French, D. Belin, J. Kiss, 1993, The Journal of cell biology.

A monoclonal antibody detecting neural and neuroendocrine differentiation.

A. Neville, A. Sappino, P. Monaghan, 1984, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

The beneficial effects of localized tumor necrosis factor production in BCG infection.

V. Kindler, A. Sappino, 1991, Behring Institute Mitteilungen.

Immunohistochemical localisation of keratin in small cell carcinoma of the lung: correlation with response to combination chemotherapy.

B. Gusterson, A. Sappino, M. Ellison, 1983, European journal of cancer & clinical oncology.

ATM gene alterations in childhood acute lymphoblastic leukemias

A. Sappino, D. Betts, P. Maillet, 2003, Human mutation.

Plasma calcitonin in small cell lung cancer: prognostic significance.

I. Smith, A. Sappino, S. Carter, 1983, British Journal of Cancer.

Excess of hMLH1 germline mutations in Swiss families with hereditary non‐polyposis colorectal cancer

P. Chappuis, P. Hutter, A. Sappino, 1998, International journal of cancer.

Heterogeneity of polyoma tumors in hamsters: Analysis of cytoskeletal proteins and viral gene expression

A. Sappino, J. Combette, H. Türler, 1990, International journal of cancer.