S. Rabbani

G. Hendy, S. Rabbani, R. Kremer, 1990, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

In vivo and In vitro Invasion , Growth , and Metastasis A Src / Abl Kinase Inhibitor , SKI-606 , Blocks Breast Cancer

S. Rabbani, F. Boschelli, Gaoping Chen, 2007 .

Urokinase/urokinase receptor and vitronectin/αvβ3 integrin induce chemotaxis and cytoskeleton reorganization through different signaling pathways

F. Blasi, S. Rabbani, S. Orlando, 2001, Oncogene.

Src-dependence and pertussis-toxin sensitivity of urokinase receptor-dependent chemotaxis and cytoskeleton reorganization in rat smooth muscle cells.

A. Villa, F. Blasi, S. Rabbani, 1999, Blood.

Effects of human prostatic mitogens on rat bone cells and fibroblasts.

M. Koutsilieris, S. Rabbani, D. Goltzman, 1987, The Journal of endocrinology.

Selective osteoblast mitogens can be extracted from prostatic tissue

M. Koutsilieris, S. Rabbani, D. Goltzman, 1986, The Prostate.

Characteristics of prostate-derived growth factors for cells of the osteoblast phenotype.

M. Koutsilieris, S. Rabbani, D. Goltzman, 1987, The Journal of clinical investigation.

Regulation of parathyroid hormone-related peptide by estradiol: effect on tumor growth and metastasis in vitro and in vivo.

G. Chen, S. Rabbani, D. Goltzman, 2005, Endocrinology.

PROSTATE CANCER: MODELS FOR DEVELOPING NOVEL THERAPEUTIC APPROACHES

A. Mazar, S. Rabbani, N. Shukeir, 2004 .

Expression of urokinase-type plasminogen activator and its receptor during ovarian follicular development.

B. Tsang, M. Li, S. Rabbani, 1997, Endocrinology.

Regulation of DNA Methylation in Human Breast Cancer

M. Szyf, S. Rabbani, A. Slack, 2002, The Journal of Biological Chemistry.

Role of mitogen-activated protein kinases in the induction of parathyroid hormone-related peptide.

S. Rabbani, D. Goltzman, J. Gladu, 2000, Cancer research.

Parathyroid Hormone-related Peptide Role of Mitogen-activated Protein Kinases in the Induction of Updated Version

S. Rabbani, D. Goltzman, J. Gladu, 2000 .

Role of Mitogen-activated Protein Kinases in the Induction of Parathyroid Hormone-related Peptide 1

S. Rabbani, D. Goltzman, J. Gladu, 2000 .

Methyl donor S-adenosylmethionine (SAM) supplementation attenuates breast cancer growth, invasion, and metastasis in vivo; therapeutic and chemopreventive applications

M. Szyf, S. Rabbani, D. Cheishvili, 2017, Oncotarget.

S‐adenosylmethionine in combination with decitabine shows enhanced anti‐cancer effects in repressing breast cancer growth and metastasis

M. Szyf, S. Rabbani, D. Cheishvili, 2020, Journal of cellular and molecular medicine.

DNA methylation signatures of Prostate Cancer in peripheral T-cells

M. Szyf, S. Rabbani, T. Bismar, 2018, BMC Cancer.

Metalloproteases and urokinase in angiogenesis and tumor progression.

S. Rabbani, 1998, In Vivo.

Induction of parathyroid hormone-related peptide by the Ras oncogene: role of Ras farnesylation inhibitors as potential therapeutic agents for hypercalcemia of malignancy.

Morag Park, S. Rabbani, D. Goltzman, 1997, Cancer research.

The Urokinase Plasminogen Activator Receptor (UPAR) Is Preferentially Induced by Nerve Growth Factor in PC12 Pheochromocytoma Cells and Is Required for NGF-Driven Differentiation

R. Farias-Eisner, H. Herschman, S. Rabbani, 2000, The Journal of Neuroscience.

An amino-terminal fragment of urokinase isolated from a prostate cancer cell line (PC-3) is mitogenic for osteoblast-like cells.

A. Mazar, J. Henkin, D. Banville, 1990, Biochemical and biophysical research communications.

An enhanced chemopreventive effect of methyl donor S-adenosylmethionine in combination with 25-hydroxyvitamin D in blocking mammary tumor growth and metastasis

M. Szyf, W. Muller, S. Rabbani, 2020, Bone Research.

Hypercalcemia of Malignancy

H. Hirte, T. Carling, G. Hendy, 2002 .

Cloning, expression, purification and functional characterization of recombinant human PSP94.

Madhulika B. Gupta, S. Rabbani, S. Garde, 2007, Protein expression and purification.

Contribution of the 37-kDa laminin receptor precursor in the anti-metastatic PSP94-derived peptide PCK3145 cell surface binding.

R. Béliveau, B. Annabi, S. Rabbani, 2006, Biochemical and biophysical research communications.

A prostate secretory protein94‐derived synthetic peptide PCK3145 inhibits VEGF signalling in endothelial cells: Implication in tumor angiogenesis

S. Lamy, B. Annabi, S. Rabbani, 2006, International journal of cancer.

Induction in human osteoblastic cells (SaOS2) of the early response genes fos, jun, and myc by the amino terminal fragment (ATF) of urokinase

A. Mazar, J. Henkin, S. Rabbani, 1997, Journal of cellular physiology.

Studies on the pathogenesis of osteoblastic metastases by prostate cancer.

S. Rabbani, D. Goltzman, I. Bolivar, 1992, Advances in experimental medicine and biology.

Molecular basis of the spectrum of skeletal complications of neoplasia

S. Rabbani, R. Kremer, D. Goltzman, 2000, Cancer.

Inhibition of processing of parathyroid hormone‐related peptide by anti‐sense furin: Effect in vitro and in vivo on rat leydig (H‐500) tumor cells

Bin Liu, S. Rabbani, N. Amizuka, 1995, International journal of cancer.

Recombinant human parathyroid hormone synthesized in Escherichia coli. Purification and characterization.

W. Sung, G. Hendy, S. Rabbani, 1988, The Journal of biological chemistry.

Synthesis and characterization of extended and deleted recombinant analogues of parathyroid hormone-(1-84): correlation of peptide structure with function.

W. Sung, G. Hendy, S. Rabbani, 1990, Biochemistry.

Studies of the multiple molecular forms of bioactive parathyroid hormone and parathyroid hormone-like substances.

M. Koutsilieris, S. Rabbani, D. Goltzman, 1986, Recent progress in hormone research.

Regulation in vivo of the growth of Leydig cell tumors by antisense ribonucleic acid for parathyroid hormone-related peptide.

S. Rabbani, D. Goltzman, B. Liu, 1995, Endocrinology.

A vitamin D analogue (EB1089) inhibits parathyroid hormone-related peptide production and prevents the development of malignancy-associated hypercalcemia in vivo.

S. Rabbani, R. Kremer, D. Goltzman, 1993, The Journal of clinical investigation.

Reversal of hypercalcemia with the vitamin D analogue EB1089 in a human model of squamous cancer.

J. Rhim, S. Rabbani, R. Kremer, 1999, Cancer research.

An antiangiogenic urokinase-derived peptide combined with tamoxifen decreases tumor growth and metastasis in a syngeneic model of breast cancer.

A. Mazar, S. Rabbani, J. Lebrun, 2002, Cancer research.

Prevention of breast cancer growth, invasion, and metastasis by antiestrogen tamoxifen alone or in combination with urokinase inhibitor B-428.

A. Mazar, J. Henkin, S. Rabbani, 1997, Cancer research.

Hypomethylation of urokinase (uPA) promoter in breast and prostate cancer: prognostic and therapeutic implications.

M. Szyf, S. Rabbani, Pouya Pakneshan, 2005, Current cancer drug targets.

A peptide derived from the nonreceptor binding region of urokinase plasminogen activator (uPA) inhibits tumor progression and angiogenesis and induces tumor cell death in vivo

A. Mazar, D. Cines, S. Rabbani, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Effect of Herceptin on the development and progression of skeletal metastases in a xenograft model of human breast cancer

S. Rabbani, Gaoping Chen, A. Arakelian, 2005, Oncogene.

Induction of osteoblast differentiation indexes by PTHrP in MG-63 cells involves multiple signaling pathways.

S. Rabbani, D. Goltzman, J. Gladu, 2001, American journal of physiology. Endocrinology and metabolism.

Androgen regulation of parathyroid hormone-related peptide production in human prostate cancer cells.

D. Miao, S. Rabbani, D. Goltzman, 2003, Endocrinology.

Epigenomic effects of vitamin D in colorectal cancer.

S. Rabbani, D. Goltzman, M. Kerachian, 2022, Epigenomics.

Synthetic inhibitor of matrix metalloproteases decreases tumor growth and metastases in a syngeneic model of rat prostate cancer in vivo

S. Davidsen, S. Rabbani, Y. Guo, 2000, International journal of cancer.

Expression and characterization of recombinant rat parathyroid hormone-related peptide (1–141) and an amino-terminally-truncated analogue (38–141)

R. Sauvé, G. Hendy, S. Rabbani, 1997, Molecular and Cellular Endocrinology.

Increased PTHRP production by a tyrosine kinase oncogene, Tpr-Met: role of the Ras signaling pathway.

Morag Park, S. Rabbani, D. Goltzman, 1996, The American journal of physiology.

Purification of peptides with parathyroid hormone-like bioactivity from human and rat malignancies associated with hypercalcemia.

S. Rabbani, R. Kremer, D. Goltzman, 1986, Endocrinology.

Inhibition of MMP-9 secretion by the anti-metastatic PSP94-derived peptide PCK3145 requires cell surface laminin receptor signaling

R. Béliveau, B. Annabi, S. Rabbani, 2006, Anti-cancer drugs.

ErbB-2 induces the cyclin D1 gene in prostate epithelial cells in vitro and in vivo.

Michael C. Ostrowski, R. Datar, R. Cote, 2007, Cancer research.

Biosynthesis and processing of endogenous parathyroid hormone related peptide (PTHRP) by rat Leydig cell tumor H-500.

S. Rabbani, D. Goltzman, M. Haq, 1993, Biochemistry.

Estradiol-dependent regulation of angiopoietin expression in breast cancer cells

R. Harfouche, S. Hussain, S. Rabbani, 2011, The Journal of Steroid Biochemistry and Molecular Biology.

Co-Targeting Luminal B Breast Cancer with S-Adenosylmethionine and Immune Checkpoint Inhibitor Reduces Primary Tumor Growth and Progression, and Metastasis to Lungs and Bone

M. Szyf, S. Rabbani, C. Piccirillo, 2022, Cancers.

Structural requirements for the growth factor activity of the amino-terminal domain of urokinase.

A. Mazar, J. Henkin, S. Rabbani, 1992, The Journal of biological chemistry.

DNA methylation and breast cancer.

M. Szyf, S. Rabbani, Pouya Pakneshan, 2004, Biochemical pharmacology.

Transcriptional regulation of urokinase (uPA) gene expression in breast cancer cells: Role of DNA methylation.

S. Rabbani, R. Xing, Shafaat A. Rabbani, 1999, International journal of cancer.

Multifaceted Role of the Urokinase-Type Plasminogen Activator (uPA) and Its Receptor (uPAR): Diagnostic, Prognostic, and Therapeutic Applications

S. Rabbani, C. Mihalcioiu, Niaz Mahmood, 2018, Front. Oncol..

A Src/Abl kinase inhibitor, SKI-606, blocks breast cancer invasion, growth, and metastasis in vitro and in vivo.

S. Rabbani, F. Boschelli, Gaoping Chen, 2007, Cancer research.

PEGylated DX-1000: pharmacokinetics and antineoplastic activity of a specific plasmin inhibitor.

L. Devy, D. Dransfield, S. Rabbani, 2007, Neoplasia.

Targeting DNA Hypomethylation in Malignancy by Epigenetic Therapies.

S. Rabbani, Niaz Mahmood, 2019, Advances in experimental medicine and biology.

Role of Methylation in Pro- and Anti-Cancer Immunity

S. Rabbani, Ali Mehdi, 2021, Cancers.

DNA Methylation Readers and Cancer: Mechanistic and Therapeutic Applications

S. Rabbani, Niaz Mahmood, 2019, Front. Oncol..

A non–RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivo

D. Shaw, A. Mazar, G. Parry, 2006, Molecular Cancer Therapeutics.

Evaluating distant metastases in breast cancer: from biology to outcomes

A. Mazar, S. Rabbani, 2007, Cancer and Metastasis Reviews.

Synergistic effects of combined DNA methyltransferase inhibition and MBD2 depletion on breast cancer cells; MBD2 depletion blocks 5-aza-2'-deoxycytidine-triggered invasiveness.

M. Szyf, M. Hallett, S. Rabbani, 2014, Carcinogenesis.

Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo.

M. Szyf, S. Rabbani, B. Ateeq, 2008, Neoplasia.

DNA demethylation and cancer: therapeutic implications.

M. Szyf, S. Rabbani, Pouya Pakneshan, 2004, Cancer letters.

S-adenosylmethionine blocks tumorigenesis and with immune checkpoint inhibitor enhances anti-cancer efficacy against BRAF mutant and wildtype melanomas

M. Szyf, S. Rabbani, C. Piccirillo, 2023, Neoplasia.

Methyl-CpG binding domain 2 (Mbd2) deficiency causes cognitive, social and emotional deficits and down-regulation of ortholog Autism risk genes

M. Szyf, Y. Yarden, S. Rabbani, 2018 .

Methyl-CpG binding domain 2 (Mbd2) is an epigenetic regulator of autism-risk genes and cognition

M. Szyf, Y. Yarden, L. Welikovitch, 2018, bioRxiv.

Rat parathyroid hormone-like peptide: comparison with the human homologue and expression in malignant and normal tissue.

D. Banville, G. Hendy, S. Rabbani, 1989, Molecular endocrinology.

Role of epigenetics in cancer initiation and progression.

M. Szyf, S. Rabbani, Flora Chik, 2011, Advances in experimental medicine and biology.

S-adenosylmethionine blocks osteosarcoma cells proliferation and invasion in vitro and tumor metastasis in vivo: therapeutic and diagnostic clinical applications

M. Szyf, Z. Hussain, S. Rabbani, 2015, Cancer medicine.

Cyclin D1 cooperates with p21 to regulate TGFβ-mediated breast cancer cell migration and tumor local invasion

S. Rabbani, J. Lebrun, Jimin Guo, 2013, Breast Cancer Research.

Over‐production of parathyroid hormone–related peptide results in increased osteolytic skeletal metastasis by prostate cancer cells In vivo

S. Rabbani, D. Goltzman, B. Jamison, 1999, International journal of cancer.

Vitamin D and Vitamin D Analogs in Cancer Progression and Metastasis

S. Rabbani, R. Kremer, 2005 .

Methyl-CpG binding domain 2 (Mbd2) is an epigenetic regulator of autism-risk genes and cognition

M. Szyf, Y. Yarden, A. Cuello, 2018, bioRxiv.

LRP5 knockdown: effect on prostate cancer invasion growth and skeletal metastasis in vitro and in vivo

S. Rabbani, A. Arakelian, R. Farookhi, 2013, Cancer medicine.

Urokinase overproduction results in increased skeletal metastasis by prostate cancer cells in vivo.

S. Rabbani, P. Brodt, D. Goltzman, 1994, Cancer research.

Expression of the urokinase plasminogen activator receptor is transiently required during “priming” of PC12 cells in nerve growth factor‐directed cellular differentiation

S. Reddy, R. Farias-Eisner, R. Bradshaw, 2001, Journal of neuroscience research.

Reversal of the Hypomethylation Status of Urokinase (uPA) Promoter Blocks Breast Cancer Growth and Metastasis*

M. Szyf, R. Farias-Eisner, S. Rabbani, 2004, Journal of Biological Chemistry.

A PSP94-derived Peptide PCK3145 inhibits MMP-9 Secretion and Triggers CD44 Cell Surface Shedding: Implication in Tumor Metastasis

R. Béliveau, B. Annabi, S. Rabbani, 2005, Clinical & Experimental Metastasis.

Expression of RANKL/RANK/OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation

A. Potti, S. Rabbani, D. Goltzman, 2006, Cancer.

A novel function for p21Cip1 and acetyltransferase p/CAF as critical transcriptional regulators of TGFβ-mediated breast cancer cell migration and invasion

S. Rabbani, J. Lebrun, A. Arakelian, 2012, Breast Cancer Research.

Prostate secretory protein of 94 amino acids (PSP-94) and its peptide (PCK3145) as potential therapeutic modalities for prostate cancer

S. Rabbani, N. Shukeir, S. Garde, 2005, Anti-cancer drugs.

SH2B1beta (SH2-Bbeta) enhances expression of a subset of nerve growth factor-regulated genes important for neuronal differentiation including genes encoding urokinase plasminogen activator receptor and matrix metalloproteinase 3/10.

Linyi Chen, J. Schwartz, T. Maures, 2008, Molecular endocrinology.

Demethylation of Urokinase Promoter as a Prognostic Marker in Patients with Breast Carcinoma

S. Rabbani, Pouya Pakneshan, B. Têtu, 2004, Clinical Cancer Research.

Genome-Wide Study of Hypomethylated and Induced Genes in Patients with Liver Cancer Unravels Novel Anticancer Targets

M. Szyf, M. Hallett, Ze-Guang Han, 2014, Clinical Cancer Research.

uPAR antibody (huATN-658) and Zometa reduce breast cancer growth and skeletal lesions

A. Mazar, S. Rabbani, A. Arakelian, 2020, Bone Research.

Urokinase/urokinase receptor and vitronectin/alpha(v)beta(3) integrin induce chemotaxis and cytoskeleton reorganization through different signaling pathways.

F. Blasi, S. Rabbani, S. Orlando, 2001, Oncogene.

Fibrinolytic System and Cancer: Diagnostic and Therapeutic Applications

S. Rabbani, Niaz Mahmood, 2021, International journal of molecular sciences.

Plasminogen Activator System — Diagnostic, Prognostic and Therapeutic Implications in Breast Cancer

S. Rabbani, Catherine Leurer, 2015 .

Overexpression of urokinase receptor in breast cancer cells results in increased tumor invasion, growth and metastasis

S. Rabbani, Rosie Hongmei Xing, Shafaat Ahmed Rabbani, 1996, International journal of cancer.

Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo.

M. Szyf, S. Rabbani, N. Shukeir, 2006, Cancer research.

Urokinase receptor antibody can reduce tumor volume and detect the presence of occult tumor metastases in vivo.

S. Rabbani, J. Gladu, Julienne Gladu, 2002, Cancer research.

Role of urokinase (uPA) and its receptor (uPAR) in invasion and metastasis of hormone-dependent malignancies.

S. Rabbani, R. Xing, S A Rabbani, 1998, International journal of oncology.

Enhanced Anticancer Effect of a Combination of S-adenosylmethionine (SAM) and Immune Checkpoint Inhibitor (ICPi) in a Syngeneic Mouse Model of Advanced Melanoma

M. Szyf, S. Rabbani, C. Piccirillo, 2020, Frontiers in Oncology.

Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: potential pathogenetic and prognostic implications.

A. Potti, S. Rabbani, D. Goltzman, 2004, Cancer.

Methylation and inhibition of expression of uPA by the RAS oncogene: divergence of growth control and invasion in breast cancer cells.

M. Szyf, S. Rabbani, Pouya Pakneshan, 2004, Carcinogenesis.

Methylation status of uPA promoter as a molecular mechanism regulating prostate cancer invasion and growth in vitro and in vivo

S. Rabbani, R. Xing, Pouya Pakneshan, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Pharmacological methyl group donors block skeletal metastasis in vitro and in vivo

M. Szyf, S. Rabbani, N. Shukeir, 2015, British journal of pharmacology.

Methyl-CpG binding domain protein 2 plays a causal role in breast cancer growth and metastasis

M. Szyf, S. Rabbani, A. Arakelian, 2020, bioRxiv.

Induction of urinary plasminogen activator by retinoic acid results in increased invasiveness of human prostate cancer cells PC‐3

S. Rabbani, Dong Feng Liu, 1995, The Prostate.

DNA methylation signatures of breast cancer in peripheral T-cells

M. Szyf, S. Rabbani, R. Kremer, 2018, BMC cancer.

Histidine-proline-rich glycoprotein has potent antiangiogenic activity mediated through the histidine-proline-rich domain.

D. Shaw, A. Mazar, G. Parry, 2002, Cancer research.

Molecular mechanism of action of parathyroid hormone related peptide in hypercalcemia of malignancy: therapeutic strategies (review).

S. Rabbani, 2000, International journal of oncology.

Influence of the amino-terminus on in vitro and in vivo biological activity of synthetic parathyroid hormone-like peptides of malignancy.

G. Hendy, S. Rabbani, D. Goltzman, 1988, Endocrinology.

DNA methylation signatures of breast cancer in peripheral T-cells

M. Szyf, S. Rabbani, R. Kremer, 2018, BMC Cancer.

Identification of an Epigenetic Signature of Osteoporosis in Blood DNA of Postmenopausal Women

M. Szyf, S. Rabbani, R. Kremer, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Coordinated expression of the vitronectin receptor and the urokinase-type plasminogen activator receptor in metastatic melanoma cells.

J. Nip, S. Rabbani, P. Brodt, 1995, The Journal of clinical investigation.

SKI-606 (Bosutinib) Blocks Prostate Cancer Invasion, Growth, and Metastasis In vitro and In vivo through Regulation of Genes Involved in Cancer Growth and Skeletal Metastasis

S. Rabbani, F. Boschelli, A. Arakelian, 2010, Molecular Cancer Therapeutics.

Binding and internalization of NGR-peptide-targeted liposomal doxorubicin (TVT-DOX) in CD13-expressing cells and its antitumor effects

S. Rabbani, S. Garde, Jinzi J. Wu, 2007, Anti-cancer drugs.

Prostate secretory protein PSP-94 decreases tumor growth and hypercalcemia of malignancy in a syngenic in vivo model of prostate cancer.

S. Rabbani, N. Shukeir, S. Garde, 2003, Cancer research.

Regulation of parathyroid hormone-related peptide production in vitro by the rat hypercalcemic Leydig cell tumor H-500.

S. Rabbani, D. Goltzman, B. Liu, 1993, Endocrinology.

Studies of the molecular biology of parathyroid hormone-like peptide.

G. Hendy, S. Rabbani, R. Kremer, 1992, Journal of endocrinological investigation.