P. Bray

发表

Effects of genetic variation in protease activated receptor 4 after an acute coronary syndrome: Analysis from the TRACER trial.

C. Shaw, C. Held, P. Armstrong, 2018, Blood cells, molecules & diseases.

Transfection of Human Platelets with Short Interfering RNA

P. Bray, W. Hong, A. Kondkar, 2011, Clinical and translational science.

The Pl(A2) polymorphism of integrin beta(3) enhances outside-in signaling and adhesive functions.

P. Bray, K. Vijayan, P. Goldschmidt-Clermont, 2000, The Journal of clinical investigation.

Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP

C. Shaw, L. Simon, L. Edelstein, 2017, Thrombosis and Haemostasis.

The complex transcriptional landscape of the anucleate human platelet

I. Rigoutsos, P. Fortina, Huang-wen Chen, 2013, BMC Genomics.

A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders.

Sri V. V. Deevi, W. Ouwehand, A. Attwood, 2016, Blood.

Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs

Yi Jing, George A Calin, Chad A Shaw, 2015, Proceedings of the National Academy of Sciences.

Human Genome-Wide Association and Mouse Knockout Approaches Identify Platelet Supervillin as an Inhibitor of Thrombus Formation Under Shear Stress

Stephen N. Jones, C. Shaw, S. Leal, 2012, Circulation.

Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity.

C. Shaw, S. Leal, G. McKnight, 2010, Blood.

Specifications of the variant curation guidelines for ITGA2B/ITGB3: ClinGen Platelet Disorder Variant Curation Panel.

Kristy Lee, Minjie Luo, P. Bray, 2021, Blood advances.

Differences in responses of platelets to fluid shear stress in patients with peripheral artery disease (PAD) and coronary artery disease (CAD)

A. Lumsden, P. Lin, C. Ballantyne, 2009, Platelets.

Effect of platelet antigen polymorphism on platelet inhibition by aspirin, clopidogrel, or their combination.

P. Binkley, M. Moeschberger, R. Magorien, 2006, Journal of the American College of Cardiology.

Overexpression of cyclin D1 in the Dami megakaryocytic cell line causes growth arrest.

C. Dang, J. Dipersio, P. Bray, 1995, Blood.

Chromosomal Localization and Tissue Expression

D. T. Shiu, Y. Kan, R. Cook, 1987 .

Venous Thrombosis and Conjugated Equine Estrogen in Women Without a Uterus

R. Langer, R. Prentice, S. Sidney, 2006, Archives of internal medicine.

A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis.

J. Weiss, L. Becker, P. Bray, 1996, The New England journal of medicine.

Immobilized platelets support human colon carcinoma cell tethering, rolling, and firm adhesion under dynamic flow conditions.

O. McCarty, S. Mousa, K. Konstantopoulos, 2000, Blood.

Cloning of glycoprotein IIIa cDNA from human erythroleukemia cells and localization of the gene to chromosome 17.

R. Cook, J. Rosa, M. Shuman, 1988, Blood.

Longitudinal RNA-Seq Analysis of the Repeatability of Gene Expression and Splicing in Human Platelets Identifies a Platelet SELP Splice QTL

Robert A. Campbell, L. Simon, D. Voora, 2019, Circulation research.

Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity.

C. Shaw, S. Leal, G. McKnight, 2010, Blood.

CHAPTER 14 – Platelet Polymorphisms

P. Bray, K. Vijayan, V. Afshar-Kharghan, 2007 .

Carotid thrombosis following neck irradiation.

W. Smoker, P. Bray, G. Call, 1990, International journal of radiation oncology, biology, physics.

Sighting acute myocardial infarction through platelet gene expression

D. Ardissino, P. Fortina, M. Vitale, 2019, Scientific Reports.

Curated disease‐causing genes for bleeding, thrombotic, and platelet disorders: Communication from the SSC of the ISTH

W. Ouwehand, K. Downes, P. Reitsma, 2019, Journal of thrombosis and haemostasis : JTH.

Ex vivo cultured megakaryocytes express functional glycoprotein IIb-IIIa receptors and are capable of adenovirus-mediated transgene expression.

J. Dipersio, D. Johns, P. Bray, 1999, Blood.

Platelet hyperreactivity: predictive and intrinsic properties.

P. Bray, 2007, Hematology/oncology clinics of North America.

Platelet hyperreactivity generalizes to multiple forms of stimulation

P. Bray, A. Bergeron, J. Dong, 2006, Journal of thrombosis and haemostasis : JTH.

Pharmacogenomics of platelet inhibitors

S. Leal, P. Bray, S. Nagalla, 2016 .

Shear stress augments the enhanced adhesive phenotype of cells expressing the Pro33 isoform of integrin β3

A. Bernardo, Yan Liu, P. Bray, 2003, FEBS letters.

Reduced inhibition by abciximab in platelets with the PlA2 polymorphism.

M. Mascelli, D. Sane, P. Bray, 2002, American heart journal.

Interaction of hemostatic genetics with hormone therapy: new insights to explain arterial thrombosis in postmenopausal women.

R. Blumenthal, W. Post, P. Bray, 2002, Chest.

The PlA polymorphism of glycoprotein IIIa functions as a modifier for the effect of estrogen on platelet aggregation.

P. Bray, P. Goldschmidt-Clermont, C. Roos, 2001, Archives of pathology & laboratory medicine.

Platelet Glycoprotein IIIa Pl A Polymorphism and Effects of Aspirin on Thrombin Generation

M. Furman, A. Michelson, P. Bray, 2001 .

Platelet glycoprotein polymorphisms as risk factors for thrombosis

P. Bray, 2000, Current opinion in hematology.

Higher prevalence of GPIIIa PlA2 polymorphism in siblings of patients with premature coronary heart disease.

L. Becker, D. Becker, R. Blumenthal, 1999, Archives of pathology & laboratory medicine.

PlA2 polymorphism and efficacy of aspirin

P. Bray, P. Goldschmidt-Clermont, G. Cooke, 1998, The Lancet.

PI A1/A2 polymorphism of platelet glycoprotein Illa and risk of cardiovascular disease

P. Bray, P. Goldschmidt-Clermont, E. Weiss, 1997, The Lancet.

Single-strand conformation polymorphism analysis is a rapid and effective method for the identification of mutations and polymorphisms in the gene for glycoprotein IIIa.

H. Dietz, P. Bray, A. Nurden, 1993, Blood.

therapy for coronary heart disease in postmenopausal women taking hormone and VI on the risk α Effect of genetic variations in platelet glycoproteins Ib

E. Vittinghoff, D. Herrington, D. Sane, 2013 .

Effect of genetic variations in platelet glycoproteins Ibalpha and VI on the risk for coronary heart disease events in postmenopausal women taking hormone therapy.

E. Vittinghoff, D. Herrington, D. Sane, 2007, Blood.

EFFECT OF GENETIC VARIATIONS IN PLATELET GLYCOPROTEINS Ibα AND VI ON THE RISK FOR CORONARY HEART DISEASE EVENTS IN POSTMENOPAUSAL WOMEN TAKING HORMONE THERAPY Platelet genes modifying hormone therapy for CHD

E. Vittinghoff, D. Herrington, D. Sane, 2006 .

Platelet reactivity and genetics down on the pharm.

P. Bray, 2006, Transactions of the American Clinical and Climatological Association.

Integrin-dependent control of translation: engagement of integrin alphaIIbbeta3 regulates synthesis of proteins in activated human platelets

D. Dixon, A. Weyrich, G. Zimmerman, 2020 .

Integrin-dependent Control of Translation: Engagement of Integrin αIIbβ3 Regulates Synthesis of Proteins in Activated Human Platelets

D. Dixon, A. Weyrich, G. Zimmerman, 1999, The Journal of cell biology.

Hormone therapy and platelet function

P. Bray, X. Leng, 2005 .

Fractalkine Is Expressed in Early and Advanced Atherosclerotic Lesions and Supports Monocyte Recruitment via CX3CR1

J. Bauersachs, P. Bray, A. Schäfer, 2012, PloS one.

PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses

P. Bray, S. Kunapuli, C. Dangelmaier, 2013, Thrombosis and Haemostasis.

Enhanced Activation of Mitogen-activated Protein Kinase and Myosin Light Chain Kinase by the Pro33 Polymorphism of Integrin β3 *

Yan Liu, P. Bray, K. Vijayan, 2003, The Journal of Biological Chemistry.

Induction of b3-Integrin Gene Expression by Sustained Activation of the Ras-Regulated Raf–MEK–Extracellular Signal-Regulated Kinase Signaling Pathway

D. Woods, M. McMahon, E. Venetsanakos, 2001 .

Platelet GP IIIa Pl(A) polymorphisms display different sensitivities to agonists.

M. Furman, M. Mascelli, S. Kundu, 2000, Circulation.

Neutrophil cathepsin G proteolysis of protease-activated receptor 4 generates a novel, functional tethered ligand

Robert A. Campbell, K. Parsawar, P. Bray, 2021, Blood advances.

A function-blocking PAR4 antibody is markedly antithrombotic in the face of a hyperreactive PAR4 variant.

L. Macdonald, A. Murphy, M. Sleeman, 2018, Blood advances.

The Traditional Role of Platelets in Hemostasis

P. Bray, D. Drelich, 2015 .

Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics.

C. Shaw, L. Simon, P. Fortina, 2014, Blood.

Platelets of Female Mice Are Intrinsically More Sensitive to Agonists Than Are Platelets of Males

P. Bray, José A López, Wei Zhang, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Differentially Modulates Cellular Migration on Extracellular Matrix Proteins

P. Bray, K. Vijayan, M. Sajid, 2002 .

PlA Polymorphism of Integrin &bgr;3 Differentially Modulates Cellular Migration on Extracellular Matrix Proteins

P. Bray, K. Vijayan, M. Sajid, 2002, Arteriosclerosis, thrombosis, and vascular biology.

One over PAR or one under PAR: vive la différence.

P. Bray, J. Di Paola, 2018, Blood.

Platelet genomics beats the catch-22.

P. Bray, 2009, Blood.

The Pro33 Isoform of Integrin β3 Enhances Outside-in Signaling in Human Platelets by Regulating the Activation of Serine/Threonine Phosphatases*

Yan Liu, Masa-aki Ito, P. Bray, 2005, Journal of Biological Chemistry.

Low prevalence and assay discordance of “aspirin resistance” in children

P. Bray, J. Teruya, L. Bomgaars, 2008, Pediatric blood & cancer.

Antiplatelet therapy in (cardio)vascular disease

J. Rogers, F. Dudbridge, A. Coffey, 2012 .

A Novel Variant in the Platelet Endothelial Aggregation Receptor-1 Gene Is Associated With Increased Platelet Aggregability

A. F. Wilson, L. Becker, D. Becker, 2008, Arteriosclerosis, thrombosis, and vascular biology.

Interventional Cardiology spirin and Clopidogrel Drug Response in atients Undergoing Percutaneous Coronary Intervention he Role of Dual Drug Resistance

N. Kleiman, P. Bray, S. Guthikonda, 2016 .

Heritability of Platelet Responsiveness to Aspirin in Activation Pathways Directly and Indirectly Related to Cyclooxygenase-1

Alexander F. Wilson, A. F. Wilson, L. Becker, 2007, Circulation.

Platelets: Developmental biology, physiology, and translatable platforms for preclinical investigation and drug development

Sunil V. Rao, S. Steinhubl, J. Freedman, 2008, Platelets.

Quantitative isolation of RNA from human platelets.

J. Rosa, P. Bray, I. Djaffar, 1991, Thrombosis research.

Human megakaryocytes possess intrinsic antiviral immunity through regulated induction of IFITM3.

Robert A. Campbell, A. Weyrich, G. Zimmerman, 2019, Blood.

Homologous recombination among three intragene Alu sequences causes an inversion-deletion resulting in the hereditary bleeding disorder Glanzmann thrombasthenia.

P. Bray, L. Li, Lu Li, 1993, American journal of human genetics.

Inherited Diseases of Platelet Glycoproteins: Considerations for Rapid Molecular Characterization

P. Bray, 1994, Thrombosis and Haemostasis.

Surface Recruitment but Not Activation of Integrin αIIbβ3 (GPIIb-IIIa) Requires a Functional Actin Cytoskeleton

P. Bray, P. Goldschmidt-Clermont, D. Grigoryev, 1995 .

THROMBOSIS AND HEMOSTASIS Anti – miR-148a regulates platelet Fc g RIIA signaling and decreases thrombosis in vivo in mice

C. Shaw, L. Edelstein, P. Bray, 2015 .

Human platelets differentially concentrate estradiol, estrone and testosterone

P. Bray, R. Hoogeveen, J. Raya, 2008, Journal of thrombosis and haemostasis : JTH.

VAMP8/endobrevin is overexpressed in hyperreactive human platelets: suggested role for platelet microRNA

Dajiang J. Liu, C. Shaw, S. Leal, 2010, Journal of thrombosis and haemostasis : JTH.

Aggregometry detects platelet hyperreactivity in healthy individuals PLATELET HYPERREACTIVITY BY AGGREGOMETRY

P. Bray, Jing-fei Dong, A. Bergeron, 2005 .

Sizing up platelet defects

P. Bray, 2008 .

Clinical and Functional Consequences of Platelet Membrane Glycoprotein Polymorphisms

P. Bray, D. Yee, Donald Yee 1, 2004, Seminars in thrombosis and hemostasis.

Platelet hyperreactivity in women from families with premature atherosclerosis.

L. Becker, D. Becker, L. Yanek, 2003, Journal of the American Medical Women's Association.

Gender Differences in Platelet GPIIb-IIIa Activation

P. Bray, P. Goldschmidt-Clermont, N. Faraday, 1997, Thrombosis and Haemostasis.

Protein Phosphatase 1 Associates with the Integrin αIIb Subunit and Regulates Signaling*

Yan Liu, P. Bray, K. Vijayan, 2004, Journal of Biological Chemistry.

Priming of Platelet αIIbβ3 by Oxidants Is Associated With Tyrosine Phosphorylation of β3

K. Irani, P. Bray, P. Goldschmidt-Clermont, 1998 .

Hereditary hemochromatosis. Diagnosis in siblings and children.

M. Carroll, P. Bray, G. Cartwright, 1977, The New England journal of medicine.

Convulsions with an occult neural-crest tumor.

J. Bale, P. Bray, 1979, The New England journal of medicine.

Megakaryocyte-specific knockout of the Mir-99b/let7e/125a cluster lowers platelet count without altering platelet function.

Ryan M. O’Connell, Robert A. Campbell, I. Rigoutsos, 2021, Blood cells, molecules & diseases.

Effects of Estrogen Replacement Therapies on Mouse Platelet Function and Glycoprotein VI Levels

B. Nieswandt, P. Bray, Wei Zhang, 2005, Circulation research.

Human megakaryocytes and platelets contain the estrogen receptor beta and androgen receptor (AR): testosterone regulates AR expression.

P. Bray, G. Khetawat, K. Vijayan, 2000, Blood.

Erosive Arthritis and Hepatic Granuloma Formation Induced by Peptidoglycan Polysaccharide in Rats Is Aggravated by Prasugrel Treatment

P. Bray, M. Rico, E. Liverani, 2013, PloS one.

Refining the treatment of women with unstable angina—A randomized, double‐blind, comparative safety and efficacy evaluation of integrelin™ versus aspirin in the management of unstable angina

R. Fox, P. Bray, K. Baughman, 1996 .

Physical linkage of the genes for platelet membrane glycoproteins IIb and IIIa.

G. Barsh, J. Rosa, M. Shuman, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Reliability of Clinical Assays for Evaluating Platelet Hypofunction.

P. Bray, Jing-fei Dong, A. Bergeron, 2005 .

Physical linkage of the genes for platelet membrane glycoproteins 1 ib and IIIa ( subchromosomal localization / pulsed-field electrophoresis / fibrinogen receptor / integrins )

G. Barsh, J. Rosa, M. Shuman, 2022 .

Quantitation of soluble fibrinogen binding to platelets by fluorescence-activated flow cytometry.

P. Bray, P. Goldschmidt-Clermont, N. Faraday, 1994, The Journal of laboratory and clinical medicine.

Gene frequencies of the five major human platelet antigens in African American, white, and Korean populations

K. Blakemore, P. Bray, Y. Jin, 1995, Transfusion.

Effects of Conjugated Equine Estrogen on Stroke in the Women’s Health Initiative

J. Buring, C. Kooperberg, B. Howard, 2006, Circulation.

Rapid genotyping of the five major platelet alloantigens by reverse dot-blot hybridization.

P. Bray, T. Kickler, Y. Jin, 1994, Blood.

A monoclonal antibody (SZ21) specific for platelet GPIIIa distinguishes P1A1 from P1A2.

P. Bray, P. Goldschmidt-Clermont, D. Grigoryev, 1995, Tissue antigens.

Beta3 integrin haplotype influences gene regulation and plasma von Willebrand factor activity.

A. Carter, P. Bray, P. Grant, 2008, Atherosclerosis.

Talin distribution and phosphorylation in thrombin-activated platelets.

M. Hensler, M. Beckerle, P. Bray, 1993, Journal of cell science.

Transdermal 17-beta estradiol replacement therapy reduces megakaryocyte GPVI expression.

B. Nieswandt, P. Bray, Wei Zhang, 2008, Thrombosis research.

Human integrin beta3 gene expression: evidence for a megakaryocytic cell-specific cis-acting element.

P. Bray, M. Villa-García, C. C. Wilhide, 1998, Blood.

Acting Element cis Cell-Specific Gene Expression : Evidence for a Megakaryocytic 3 β Human Integrin

P. Bray, Ying Jin, M. Villa-García, 1998 .

Localization of a Binding Site for Phosphatidylinositol 4,5-Bisphosphate on Human Profilin (*)

R. H. Sohn, J. Chen, P. Bray, 1995, The Journal of Biological Chemistry.

Integrin Polymorphisms as Risk Factors for Thrombosis

P. Bray, 1999, Thrombosis and Haemostasis.

CASE REPORT: Elevated Factor VIII and Portal Vein Thrombosis

P. Bray, A. Duchini, Venodhar R. Julapalli, 2003, Digestive Diseases and Sciences.

Platelet FcγRIIA HIS131ARG polymorphism and platelet function: antibodies to platelet‐bound fibrinogen induce platelet activation

A. Michelson, P. Bray, M. Barnard, 2003, Journal of thrombosis and haemostasis : JTH.

Human platelets and megakaryocytes contain alternately spliced glycoprotein IIb mRNAs.

M. Shuman, P. Bray, C. Leung, 1990, The Journal of biological chemistry.

Dengue platelets meet Sir Arthur Conan Doyle.

P. Bray, 2013, Blood.

Dengue platelets meet

P. Bray, A. Doyle, 2013 .

HHV-8-associated multicentric Castleman's disease in HIV-negative patient: a novel therapy for an orphan disease.

J. Caro, P. Bray, A. Mahipal, 2012, The oncologist.

CRISPR-edited megakaryocytes for rapid screening of platelet gene functions.

P. Bray, J. Rowley, N. Tolley, 2021, Blood advances.

High prevalence of overweight/obesity in adult persons with hemophilia in Utah and a review of the literature

A. Presson, P. Bray, G. Rodgers, 2020, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

MicroRNAs in platelet production and activation.

L. Edelstein, P. Bray, 2010, Blood.

Mechanism of Race-Dependent Platelet Activation Through the Protease-Activated Receptor-4 and Gq Signaling Axis

L. Edelstein, P. Bray, M. Holinstat, 2014, Arteriosclerosis, thrombosis, and vascular biology.

Racial Difference in Human Platelet PAR4 Reactivity Reflects Expression of PCTP and miR-376c

C. Shaw, L. Simon, E. Chen, 2013, Nature Medicine.

Integrative Multi-omic Analysis of Human Platelet eQTLs Reveals Alternative Start Site in Mitofusin 2.

C. Shaw, L. Simon, I. Rigoutsos, 2016, American journal of human genetics.

Genetic variation responsible for mouse strain differences in integrin alpha 2 expression is associated with altered platelet responses to collagen.

S. Leal, E. Rubin, B. Nieswandt, 2004, Blood.

Quantitative measurement and chromatography of human urinary carcinoembryonic antigen activity.

P. Bray, J. Wu, A. Madsen, 1974, Journal of the National Cancer Institute.

The carcinoembryonic antigen assay: Prognostic value in neural crest tumors.

D. Frens, P. Bray, J. Wu, 1976, The Journal of pediatrics.

The Platelet Transcriptome in Health and Disease

A. Weyrich, P. Bray, J. Rowley, 2019, Platelets.

Platelet biology and response to antiplatelet therapy in women: implications for the development and use of antiplatelet pharmacotherapies for cardiovascular disease.

M. Sabatine, H. Dauerman, R. Becker, 2012, Journal of the American College of Cardiology.

The human integrin beta3 gene is 63 kb and contains a 5'-UTR sequence regulating expression.

E. Rubin, P. Bray, Ying Jin, 1997, Blood.

miR‐15a‐5p regulates expression of multiple proteins in the megakaryocyte GPVI signaling pathway

L. Edelstein, A. Weyrich, P. Bray, 2019, Journal of thrombosis and haemostasis : JTH.

IsoMiRmap: fast, deterministic and exhaustive mining of isomiRs from short RNA-seq datasets

Phillipe Loher, Eric Londin, Venetia Pliatsika, 2021, Bioinform..

Noncoding RNAs in Platelet Biology

L. Edelstein, P. Bray, 2017 .

Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway

D. Woods, M. McMahon, E. Venetsanakos, 2020 .

Induction of β3-Integrin Gene Expression by Sustained Activation of the Ras-Regulated Raf–MEK–Extracellular Signal-Regulated Kinase Signaling Pathway

D. Woods, M. McMahon, E. Venetsanakos, 2001, Molecular and Cellular Biology.

Kinase Signaling Pathway Extracellular Signal-Regulated − MEK − Raf Sustained Activation of the Ras-Regulated 3-Integrin Gene Expression by β Induction of

D. Woods, M. McMahon, E. Venetsanakos, 2001 .

Identification of an abnormal gene for the GPIIIa subunit of the platelet fibrinogen receptor resulting in Glanzmann's thrombasthenia.

M. Shuman, P. Bray, Marc A. Shuman, 1990, Blood.

Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race.

C. Shaw, L. Simon, S. Coughlin, 2014, Blood.

Chapter 4 – Platelet Genomics

Chris I. Jones, W. Ouwehand, N. Soranzo, 2013 .

MicroRNAs in platelet production and activation

C. Shaw, L. Edelstein, P. Bray, 2013, Journal of thrombosis and haemostasis : JTH.

Heritability of platelet function in families with premature coronary artery disease

Alexander F. Wilson, A. F. Wilson, L. Becker, 2007, Journal of thrombosis and haemostasis : JTH.

Small RNAs as potential platelet therapeutics.

L. Edelstein, P. Bray, 2012, Handbook of experimental pharmacology.

Megakaryocyte-targeted synthesis of the integrin beta(3)-subunit results in the phenotypic correction of Glanzmann thrombasthenia.

J. Olsen, P. Bray, W. Bell, 2000, Blood.

Glutathione regulates integrin αIIbβ3-mediated cell adhesion under flow conditions

C. Ball, T. Nguyen, D. Essex, 2008, Thrombosis and Haemostasis.

CLINICAL RESEARCH Interventional Cardiology Aspirin and Clopidogrel Drug Response in Patients Undergoing Percutaneous Coronary Intervention The Role of Dual Drug Resistance

J. Granada, N. Kleiman, E. Lev, 2006 .

The protease‐activated receptor 4 Ala120Thr variant alters platelet responsiveness to low‐dose thrombin and protease‐activated receptor 4 desensitization, and is blocked by non‐competitive P2Y12 inhibition

C. Shaw, E. Chen, L. Edelstein, 2018, Journal of thrombosis and haemostasis : JTH.

R to Q amino acid substitution in the GFFKR sequence of the cytoplasmic domain of the integrin IIb subunit in a patient with a Glanzmann's thrombasthenia-like syndrome.

N. Kieffer, P. Bray, A. Nurden, 1998, Blood.

Isolation and characterization of a TATA-less promoter for the human beta 3 integrin gene.

Gregory Riely, P. Bray, M. Villa-García, 1994, Blood.

The PlA2 polymorphism of integrin β3 enhances outside-in signaling and adhesive functions

P. Bray, K. Vijayan, P. Goldschmidt-Clermont, 2000 .

The role of HLA antibodies in neonatal thrombocytopenia: a prospective study.

S. Kennedy, K. Blakemore, P. Bray, 1996, Tissue antigens.

Molecular genotyping of fetal platelet antigens with uncultured amniocytes.

K. Blakemore, P. Bray, A. Sciscione, 1995, American journal of obstetrics and gynecology.

Aggregometry detects platelet hyperreactivity in healthy individuals.

P. Bray, Jing-fei Dong, A. Bergeron, 2005, Blood.

Genetics of Arterial Prothrombotic Risk States

P. Bray, Marlene S. Williams, Marlene S Williams, 2001, Experimental biology and medicine.

Genome-wide association study of platelet aggregation in African Americans

S. Leal, L. Becker, D. Becker, 2015, BMC Genetics.

Anti-apoptotic BCL2L2 increases megakaryocyte proplatelet formation in cultures of human cord blood

Robert A. Campbell, L. Edelstein, A. Weyrich, 2019, Haematologica.

Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression.

Andrew D. Johnson, A. Gylfason, U. Thorsteinsdóttir, 2011, Blood.

Incidence and Prognostic Implications of Stable Angina Pectoris Among Women and Men

J. Segal, L. Becker, D. Becker, 2006, Journal of the American Medical Association (JAMA).

Antibodies against Epstein-Barr nuclear antigen (EBNA) in multiple sclerosis CSG and two pentapepfide seauence identities between EBNA A and myelin basic protein

P. Bray, P. Bray, J. Luka, 1992, Neurology.

Glanzmann thrombasthenia. Cooperation between sequence variants in cis during splice site selection.

H. Dietz, R. Montgomery, P. Bray, 1996, The Journal of clinical investigation.

The minor allele of GP6 T13254C is associated with decreased platelet activation and a reduced risk of recurrent cardiovascular events and mortality: results from the SMILE–Platelets project

F. Rosendaal, D. Herrington, H. Vos, 2010, Journal of thrombosis and haemostasis : JTH.

miR-125a-5p Regulates Megakaryocyte Proplatelet Formation Via the Actin Bundling Protein L-Plastin.

Ryan M. O’Connell, Robert A. Campbell, L. Edelstein, 2020, Blood.

MicroRNA Expression Differences in Human Hematopoietic Cell Lineages Enable Regulated Transgene Expression

C. Shaw, L. Edelstein, P. Bray, 2014, PloS one.

Leukocyte count as a predictor of cardiovascular events and mortality in postmenopausal women: the Women's Health Initiative Observational Study.

J. Manson, R. Prentice, B. Howard, 2005, Archives of internal medicine.

A comprehensive high-throughput sequencing test for the diagnosis of inherited bleeding , thrombotic and platelet disorders

Sri V. V. Deevi, W. Ouwehand, J. Jolley, 2015 .

Biogenesis of the platelet receptor for fibrinogen: evidence for separate precursors for glycoproteins IIb and IIIa.

Y. Kan, J. Rosa, V. Lingappa, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Platelet tyrosine kinases and fibrinogen receptor activation.

M. Furman, P. Bray, P. Goldschmidt-Clermont, 1994, Circulation research.

Cloning of Glycoprotein LILa cDNA From Human Erythroleukemia Cells and Localization of the Gene to Chromosome

R. Cook, M. Shuman, P. Bray, 2005 .

Platelet glycoprotein IIb. Chromosomal localization and tissue expression.

D. T. Shiu, Y. Kan, R. Cook, 1987, The Journal of clinical investigation.

Duration of exposure to high fluid shear stress is critical in shear-induced platelet activation-aggregation

P. Bray, Jing-fei Dong, Jing-fei Dong, 2003, Thrombosis and Haemostasis.

Anti-miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice.

C. Shaw, L. Edelstein, P. Bray, 2015, Blood.

Platelet glycoprotein receptor IIIa polymorphism P1A2 and ischemic stroke risk: the Stroke Prevention in Young Women Study.

R. Macko, P. Stolley, R. Wityk, 1998, Stroke.

Effects of integrelin, a platelet glycoprotein IIb/IIIa receptor antagonist, in unstable angina. A randomized multicenter trial.

R. Califf, E. Topol, P. Yock, 1996, Circulation.

Advancing the Study of Stroke in Women: Summary and Recommendations for Future Research From an NINDS-Sponsored Multidisciplinary Working Group

L. Newby, P. Gorelick, L. Goldstein, 2006, Stroke.

Usefulness of baseline lipids and C-reactive protein in women receiving menopausal hormone therapy as predictors of treatment-related coronary events.

J. Manson, A. LaCroix, R. Langer, 2008, The American journal of cardiology.

Molecular Mechanisms of Prothrombotic Risk Due to Genetic Variations in Platelet Genes: Enhanced Outside-In Signaling Through the Pro33 Variant of Integrin β3

P. Bray, K. Vijayan, 2006, Experimental biology and medicine.

Fibrinogen and prothrombin binding is enhanced to the Pro33 isoform of purified integrin αIIbβ3

P. Bray, K. Vijayan, P. Thiagarajan, 2006, Journal of Thrombosis and Haemostasis.

Genetic polymorphisms of the platelet receptors P2Y(12), P2Y(1) and GP IIIa and response to aspirin and clopidogrel.

N. Kleiman, E. Lev, P. Bray, 2007, Thrombosis research.

rolling, and firm adhesion under dynamic flow conditions Immobilized platelets support human colon carcinoma cell tethering,

O. McCarty, S. Mousa, K. Konstantopoulos, 2013 .

localization of the gene to chromosome 17 Cloning of glycoprotein IIIa cDNA from human erythroleukemia cells and

R. Cook, J. Rosa, M. Shuman, 2011 .

Glanzmann thrombasthenia: genetic basis and clinical correlates

Kristy Lee, Minjie Luo, P. Bray, 2020, Haematologica.

R93W mutation in Orai1 causes impaired calcium influx in platelets.

S. Feske, P. Bray, W. Bergmeier, 2008, Blood.

Coagulation markers predicting cardiac transplant rejection.

J. Segal, R. Hruban, W. Baldwin, 2001, Transplantation.

Personalized medicine in thrombosis: back to the future.

P. Bray, S. Nagalla, 2016, Blood.

Relation between atherosclerosis risk factors and aspirin resistance in a primary prevention population.

J. Segal, L. Becker, D. Becker, 2006, The American journal of cardiology.

Peripheral Arterial Occlusive Disease: Magnetic Resonance Imaging and the Role of Aggressive Medical Management

A. Lumsden, P. Lin, C. Ballantyne, 2007, World Journal of Surgery.

Human Platelets Contain a Glycosylated Estrogen Receptor β

P. Bray, K. Vijayan, E. Bolton, 2001 .

Human Platelets Contain a Glycosylated Estrogen Receptor &bgr;

P. Bray, K. Vijayan, E. Bolton, 2001, Circulation research.

The platelet PlA2 and angiotensin-converting enzyme (ACE) D allele polymorphisms and the risk of recurrent events after acute myocardial infarction

M. Pfeffer, E. Braunwald, C. Cannon, 2001 .

The human platelet: strong transcriptome correlations among individuals associate weakly with the platelet proteome

C. Shaw, I. Rigoutsos, P. Fortina, 2014, Biology Direct.

Short running title: Platelet microRNA in platelet reactivity

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MAPK-interacting kinase 1 (Mnk1) regulates platelet production, activation, and thrombosis.

Robert A. Campbell, C. Proud, A. Weyrich, 2022, Blood.

Targeted Temperature Management after Intracerebral Hemorrhage (TTM-ICH): Methodology of a Prospective Randomized Clinical Trial

S. Mayer, F. Rincon, P. Bray, 2014, International journal of stroke : official journal of the International Stroke Society.

The Common Racially Diverse Human PAR4 Variant Thr120 Causes Worse Outcomes in a Mouse Stroke Model Via Platelet-Mediated NET Formation: Prevention By P-Selectin Blockade

Robert A. Campbell, P. Bray, M. Cody, 2022, Blood.

Blockade of Human PAR4 in Novel Humanized Mouse Strains Supports PAR4 As a Potential Target in Stroke: Ex Vivo Demonstration of Platelet Hyperreactivity of the Thr120 Variant

Robert A. Campbell, P. Bray, B. Manne, 2020 .

Genetic Variant in Human PAR (Protease-Activated Receptor) 4 Enhances Thrombus Formation Resulting in Resistance to Antiplatelet Therapeutics

L. Edelstein, P. Bray, M. Holinstat, 2018, Arteriosclerosis, thrombosis, and vascular biology.

Genome-wide association study of platelet aggregation in African Americans

C. Shaw, S. Leal, L. Becker, 2015, BMC Genetics.

The 9p21.3 locus: platelets enter the fray.

S. Leal, P. Bray, 2010, Circulation. Cardiovascular genetics.

Platelets Enter the Fray

S. Leal, P. Bray, 2010 .

Glutathione regulates integrin alpha(IIb)beta(3)-mediated cell adhesion under flow conditions.

C. Ball, D. Essex, P. Bray, 2008, Thrombosis and Haemostasis.

Platelet Gene Polymorphisms and Cardiac Risk Assessment in Vascular Surgical Patients

P. Pronovost, R. Scharpf, L. Fleisher, 2004, Anesthesiology.

TULA-2 (T-Cell Ubiquitin Ligand-2) Inhibits the Platelet Fc Receptor for IgG IIA (Fc&ggr;RIIA) Signaling Pathway and Heparin-Induced Thrombocytopenia in Mice

L. Edelstein, P. Bray, S. Kunapuli, 2016, Arteriosclerosis, Thrombosis and Vascular Biology.

The platelet Pl(A2) and angiotensin-converting enzyme (ACE) D allele polymorphisms and the risk of recurrent events after acute myocardial infarction.

M. Pfeffer, E. Braunwald, C. Cannon, 2001, The American journal of cardiology.

Acquired von Willebrand syndrome in monoclonal gammopathy – A scoping review on hemostatic management

P. Bray, G. Rodgers, Mouhamed Yazan Abou-Ismail, 2021, Research and practice in thrombosis and haemostasis.

PIA1/A2 POLYMORPHISM OF PLATELET GLYCOPROTEIN IIIA AND RISK OF CARDIOVASCULAR DISEASE. AUTHORS' REPLY

P. Ridker, K. Kario, U. Ikeda, 1997 .

Biochemical changes in liver and blood underlying parenchymal damage of rat liver induced by a dose-dependent effect of drugs before and after development of liver enlargement and nodular hyperplasia.

P. Bray, J. Nievel, J. Anderson, 1976, Biochemical Society transactions.

Platelet RNA chips dip into thrombocytosis.

P. Bray, S. Nagalla, 2010, Blood.

SNP in human ARHGEF3 promoter is associated with DNase hypersensitivity, transcript level and platelet function, and Arhgef3 KO mice have increased mean platelet volume

W. Ouwehand, L. Simon, P. van der Harst, 2017, PLoS ONE.

Comment on Gnatenko et al , page 7 Platelet RNA chips dip into thrombocytosis

Scandura, P. Bray, S. Nagalla, 2009 .

Glanzmann thrombasthenia: Genetic basis and clinical correlates

Kristy Lee, Minjie Luo, P. Bray, 2020 .

Commentary: Advancing the Research Mission in an Academic Department: The Creation of a Center for Translational Medicine

W. Koch, D. Whellan, A. Feldman, 2010, Clinical and translational science.

Protease receptor antagonism to target blood platelet therapies

P. Bray, M. Holinstat, PF Bray, 2016, Clinical pharmacology and therapeutics.

THROMBOSIS AND HEMOSTASIS A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders