D. Bullens

发表

Taste Receptors: The Gatekeepers of the Airway Epithelium

B. Steelant, K. Martens, D. Bullens, 2021, Cells.

Short running head title: Cytokine mRNA in induced sputum in asthma Correspondence address:

D. Bullens, T. Els, Coteur Liesbeth, 2017 .

Type III IFN‐λ mRNA expression in sputum of adult and school‐aged asthmatics

J. Ceuppens, L. Dupont, D. Bullens, 2008, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Evaluation of airway inflammation by quantitative Th1/Th2 cytokine mRNA measurement in sputum of asthma patients

J. Ceuppens, L. Dupont, D. Bullens, 2006, Thorax.

Regulation of the IL‐10 Production by Human T Cells

D. Bullens, A. Kasran, J. Ceuppens, 2001, Scandinavian journal of immunology.

Allergen‐specific T cells from birch‐pollen‐allergic patients and healthy controls differ in T helper 2 cytokine and in interleukin‐10 production

J. Ceuppens, D. Bullens, A. Kasran, 2004, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Effects of co-stimulation by CD58 on human T cell cytokine production: a selective cytokine pattern with induction of high IL-10 production.

J. Ceuppens, D. Bullens, A. Kasran, 2001, International immunology.

Differences in regulatory pathways identify subgroups of T cell‐derived Th2 cytokines

D. Bullens, A. Kasran, J. Ceuppens, 2000, Clinical and experimental immunology.

Staphylococcus aureus enterotoxin B facilitates allergic sensitization in experimental asthma

B. Lambrecht, C. Bachert, P. Van cauwenberge, 2010, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Effects of interleukin 4 on CD25+CD4+ regulatory T cell function.

P. Rutgeerts, G. Van Assche, J. Ceuppens, 2005, Journal of autoimmunity.

House dust mite‐specific T cells in healthy non‐atopic children

J. Ceuppens, R. Kroczek, D. Bullens, 2005, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

T1209 New Mechanism of Action for Anti-TNF Therapy in IBD: Induction of FOXP3+CD4+CD25+ and FOXP3+CD4+CD25- T Cells in Crohn's Disease and Ulcerative Colitis

P. Rutgeerts, S. Vermeire, M. Noman, 2008 .

Remission‐inducing effect of anti‐TNF monoclonal antibody in TNBS colitis: Mechanisms beyond neutralization?

P. Rutgeerts, G. Van Assche, J. Ceuppens, 2007, Inflammatory bowel diseases.

Functional expression of 4-1BB (CD137) in the inflammatory tissue in Crohn's disease.

P. Rutgeerts, G. Van Assche, J. Ceuppens, 2004, Clinical immunology.

Elevated expression of both mRNA and protein levels of IL-17A in sputum of stable Cystic Fibrosis patients

L. Dupont, D. Bullens, A. Kasran, 2010, Respiratory research.

Pepsin and bile acids in induced sputum of chronic cough patients.

S. Seys, L. Dupont, D. Bullens, 2011, Respiratory medicine.

Blocking histone deacetylase activity as a novel target for epithelial barrier defects in patients with allergic rhinitis.

P. Hellings, C. Akdis, B. Pugin, 2019, The Journal of allergy and clinical immunology.

Stepwise approach towards adoption of allergen immunotherapy for allergic rhinitis and asthma patients in daily practice in Belgium: a BelSACI-Abeforcal-EUFOREA statement

J. Bousquet, C. Bachert, P. Hellings, 2019, Clinical and Translational Allergy.

Aggravation of bronchial eosinophilia in mice by nasal and bronchial exposure to Staphylococcus aureus enterotoxin B

C. Bachert, P. Gevaert, J. Ceuppens, 2006, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Corticosteroids for sore throat: a clinical practice guideline

T. Agoritsas, A. Van den Bruel, D. Bullens, 2017, British Medical Journal.

Validating a decision tree for serious infection: diagnostic accuracy in acutely ill children in ambulatory care

A. Van den Bruel, D. Bullens, F. Buntinx, 2015, BMJ Open.

Involvement of 4‐1BB (CD137)−4‐1BBligand interaction in the modulation of CD4+ T cell‐mediated inflammatory colitis

P. Rutgeerts, G. Van Assche, J. Ceuppens, 2006, Clinical and experimental immunology.

Effects of high altitude and cold air exposure on airway inflammation in patients with asthma

S. Seys, P. Hespel, L. Dupont, 2013, Thorax.

Murine bone marrow chimeras developing autoimmunity after CTLA-4-blockade show an expansion of T regulatory cells with an activated cytokine profile.

L. Boon, C. Mathieu, D. Bullens, 2010, Immunology letters.

Exercise and Sinonasal Disease.

V. Hox, S. Seys, B. Steelant, 2018, Immunology and allergy clinics of North America.

Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-γ

A. Billiau, D. Bullens, G. Leclercq, 2005, Arthritis research & therapy.

Restoration of Foxp3+ Regulatory T-cell Subsets and Foxp3− Type 1 Regulatory-like T Cells in Inflammatory Bowel Diseases During Anti-tumor Necrosis Factor Therapy

K. Van Steen, P. Rutgeerts, S. Vermeire, 2015, Inflammatory bowel diseases.

Cells with Regulatory Cell Activity Inducible Costimulator-Expressing Anergic T Signal-Deficient Allogeneic Cells Induces Human T Cell Activation by Costimulatory

Richard, J. Ceuppens, H. Mages, 2004 .

Obese individuals with asthma preferentially have a high IL-5/IL-17A/IL-25 sputum inflammatory pattern.

S. Seys, J. Ceuppens, L. Dupont, 2014, American journal of respiratory and critical care medicine.

New insights in neutrophilic asthma

S. Seys, D. Bullens, J. Simpson, 2019, Current opinion in pulmonary medicine.

T-cell mediated late increase in bronchial tone after allergen provocation in a murine asthma model.

P. Hellings, C. Mathieu, J. Ceuppens, 2008, Clinical immunology.

Crucial role of transient receptor potential ankyrin 1 and mast cells in induction of nonallergic airway hyperreactivity in mice.

P. Hellings, V. Hox, A. Liston, 2013, American journal of respiratory and critical care medicine.

IL-17A in Human Respiratory Diseases: Innate or Adaptive Immunity? Clinical Implications

S. Seys, L. Dupont, D. Bullens, 2013, Clinical & developmental immunology.

Histamine and T helper cytokine–driven epithelial barrier dysfunction in allergic rhinitis

P. Hellings, C. Akdis, S. Seys, 2017, The Journal of allergy and clinical immunology.

Damage‐associated molecular pattern and innate cytokine release in the airways of competitive swimmers

P. Hellings, V. Hox, S. Seys, 2015, Allergy.

IL-12 Contributes to Allergen-Induced Airway Inflammation in Experimental Asthma1

P. Hellings, C. Mathieu, J. Ceuppens, 2006, The Journal of Immunology.

Differential effects of intense exercise and pollution on the airways in a murine model

L. Dupont, D. Bullens, J. Vanoirbeek, 2021, Particle and fibre toxicology.

Occurrence of autoimmunity after xenothymus transplantation in T-cell-deficient mice depends on the thymus transplant technique.

C. Mathieu, C. de Wolf‐Peeters, W. Landuyt, 2008, Transplantation.

Clinical‐Grade Human Multipotent Adult Progenitor Cells Block CD8+ Cytotoxic T Lymphocytes

C. Verfaillie, D. Bullens, S. V. Van Gool, 2016, Stem cells translational medicine.

IL-10- and IL-12-Independent Down-Regulation of Allergic Sensitization by Stimulation of CD40 Signaling1

P. Hellings, L. Boon, C. Mathieu, 2006, The Journal of Immunology.

Stimulation of CD40 Signaling Down-Regulation of Allergic Sensitization by IL-10- and IL-12-Independent

L. Boon, D. Bullens, H. Heremans, 2006 .

Early-onset airway damage in early-career elite athletes: a risk factor for exercise-induced bronchoconstriction.

S. Seys, T. Troosters, L. Dupont, 2019, The Journal of allergy and clinical immunology.

The role of interleukin-17 during acute rejection after lung transplantation

G. Verleden, L. Dupont, W. Wuyts, 2006, European Respiratory Journal.

Immunotherapy with a modified birch pollen extract in allergic rhinoconjunctivitis: clinical and immunological effects

J. Ceuppens, D. Bullens, H. Kleinjans, 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Piliation of Lactobacillus rhamnosus GG Promotes Adhesion, Phagocytosis, and Cytokine Modulation in Macrophages

I. von Ossowski, S. Lebeer, A. Palva, 2015, Applied and Environmental Microbiology.

Impact of lipoteichoic acid modification on the performance of the probiotic Lactobacillus rhamnosus GG in experimental colitis

P. Rutgeerts, S. Vermeire, G. V. Assche, 2010, Clinical and experimental immunology.

Sensitization to Inhaled Ryegrass Pollen by Collateral Priming in a Murine Model of Allergic Respiratory Disease

J. Ceuppens, D. Bullens, J. Vanoirbeek, 2010, International Archives of Allergy and Immunology.

Serum and sputum calprotectin, a reflection of neutrophilic airway inflammation in asthmatics after high‐altitude exposure

P. Hellings, V. Hox, S. Seys, 2017, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Effect of Nasal Anti-Inflammatory Treatment in Chronic Obstructive Pulmonary Disease

P. Hellings, V. Hox, W. Janssens, 2013, American journal of rhinology & allergy.

Selective nasal allergen provocation induces substance P-mediated bronchial hyperresponsiveness.

P. Hellings, J. Ceuppens, D. Bullens, 2011, American journal of respiratory cell and molecular biology.

Staphylococcus aureus enterotoxin B augments granulocyte migration and survival via airway epithelial cell activation

C. Bachert, D. Bullens, J. Ceuppens, 2010, Allergy.

Type III interferon-λ mRNA expression in sputum of adult and school-aged asthmatics

J. Ceuppens, L. Dupont, D. Bullens, 2008 .

Elevated serum calprotectin (S100A8/A9) in patients with severe asthma

L. Dupont, D. Bullens, J. Vanoirbeek, 2021, The Journal of asthma : official journal of the Association for the Care of Asthma.

Feasibility to apply eucapnic voluntary hyperventilation in young elite athletes.

S. Seys, T. Troosters, L. Dupont, 2016, Respiratory medicine.

CD40L‐Induced IL‐12 Production is Further Enhanced by the Th2 Cytokines IL‐4 and IL‐13

J. Ceuppens, D. Bullens, A. Kasran, 2001, Scandinavian journal of immunology.

Contribution of Regulatory T Cells and Effector T Cell Deletion in Tolerance Induction by Costimulation Blockadel

L. Boon, J. Ceuppens, D. Bullens, 2008, The Journal of Immunology.

Programmed cell death‐1 expression correlates with disease severity and IL‐5 in chronic rhinosinusitis with nasal polyps

C. Bachert, P. Hellings, N. Zhang, 2017, Allergy.

A hypoallergenic variant of Der p 1 as a candidate for mite allergy vaccines.

M. El Bakkoury, D. Bullens, M. Vandenbranden, 2009, The Journal of allergy and clinical immunology.

Influence of Toll-like-receptor ligands on the dendritic cell-T cell interactions: therapeutic options for allergic diseases? Mini-review.

J. Ceuppens, D. Bullens, 2008, Inflammation & allergy drug targets.

In vivo maturation of T(H) cells in relation to atopy.

J. Ceuppens, D. Bullens, A. Kasran, 2011, The Journal of allergy and clinical immunology.

Diagnosing serious infections in acutely ill children in ambulatory care (ERNIE 2 study protocol, part A): diagnostic accuracy of a clinical decision tree and added value of a point-of-care C-reactive protein test and oxygen saturation

D. Bullens, F. Buntinx, B. Aertgeerts, 2014, BMC Pediatrics.

Monitoring the effect of allergen immunotherapy: a clinician's dream comes true?

D. Bullens, 2010, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Rapidly induced, T-cell independent xenoantibody production is mediated by marginal zone B cells and requires help from NK cells.

L. Boon, D. Bullens, A. Kasran, 2007, Blood.

Ligation of CD2 provides a strong helper signal for the production of the type 2 cytokines interleukin-4 and -5 by memory T cells.

J. Ceuppens, D. Bullens, A. Kasran, 1997, Cellular immunology.

Neonatal IL‐10 production and risk of allergy development

J. Ceuppens, D. Bullens, A. Kasran, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Guided Gradual Egg-Tolerance Induction in Hen's Egg Allergic Children Tolerating Baked Egg: A Prospective Randomized Trial

C. Matthys, D. Bullens, R. Schrijvers, 2022, Frontiers in Allergy.

Searching for regulatory T cells in allergy: are we nearing the ‘Finish’?

D. Bullens, 2008, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

4th Pediatric Allergy and Asthma Meeting (PAAM)

Manuel A. R. Ferreira, C. Gieger, D. Postma, 2016, Clinical and Translational Allergy.

Alpha-amylase as the culprit in an occupational mealworm allergy case

P. Proost, D. Bullens, C. Breynaert, 2022, Frontiers in Allergy.

AQUA© Questionnaire as prediction tool for atopy in young elite athletes

S. Seys, T. Troosters, L. Dupont, 2018, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?

P. Hellings, J. Ceuppens, L. Dupont, 2006, Respiratory research.

Low cord blood Foxp3/CD3γ mRNA ratios: a marker of increased risk for allergy development

S. Seys, J. Ceuppens, L. Dupont, 2015, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Staphylococcus aureus enterotoxin B disrupts nasal epithelial barrier integrity

S. Seys, B. Steelant, S. Lebeer, 2020, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Inhibition of glycolipid biosynthesis by N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin protects against the inflammatory response in hapten-induced colitis.

J. M. Aerts, P. Rutgeerts, L. Boon, 2004, International immunopharmacology.

Immunotherapy with subcutaneous immunogenic autologous tumor lysate increases murine glioblastoma survival

D. Bullens, S. V. Van Gool, B. Creyns, 2017, Scientific Reports.

Immunological Outcomes of Allergen-Specific Immunotherapy in Food Allergy

K. Verhoeckx, J. Garssen, Karine Patient, 2020, Frontiers in Immunology.

Delayed‐type drug hypersensitivity caused by paracetamol in a 2‐year‐old boy, confirmed by a positive patch test reaction and oral provocation

D. Bullens, A. Goossens, M. Morren, 2018, Contact dermatitis.

Innate Lymphoid Cells Are Required to Induce Airway Hyperreactivity in a Murine Neutrophilic Asthma Model

S. Seys, B. Steelant, J. Ceuppens, 2022, Frontiers in Immunology.

Impaired barrier function in patients with house dust mite-induced allergic rhinitis is accompanied by decreased occludin and zonula occludens-1 expression.

P. Hellings, C. Akdis, S. Seys, 2016, The Journal of allergy and clinical immunology.

Point-of-care C reactive protein to identify serious infection in acutely ill children presenting to hospital: prospective cohort study

A. Van den Bruel, D. Bullens, F. Buntinx, 2017, Archives of Disease in Childhood.

Sputum cytokine mapping reveals an ‘IL‐5, IL‐17A, IL‐25‐high’ pattern associated with poorly controlled asthma

S. Seys, J. Ceuppens, L. Dupont, 2013, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Reciprocal changes of Foxp3 expression in blood and intestinal mucosa in IBD patients responding to infliximab†

P. Rutgeerts, S. Vermeire, M. Noman, 2010, Inflammatory bowel diseases.

Human T Cell Activation by Costimulatory Signal-Deficient Allogeneic Cells Induces Inducible Costimulator-Expressing Anergic T Cells with Regulatory Cell Activity1

J. Ceuppens, H. Mages, R. Kroczek, 2004, The Journal of Immunology.

Mast cell leukemia: clinical and molecular features and survival outcomes of patients in the ECNM Registry

M. Triggiani, J. Panse, H. Kluin-Nelemans, 2022, Blood advances.

Original article: Sinonasal pathology in nonallergic asthma and COPD: ‘united airway disease’ beyond the scope of allergy

M. Decramer, P. Hellings, J. Ceuppens, 2007, Allergy. European Journal of Allergy and Clinical Immunology.

A Clinical Perspective on the Dietary Therapies for Pediatric Eosinophilic Esophagitis: The Gap Between Research and Daily Practice

D. Bullens, C. Breynaert, T. Vanuytsel, 2021, Frontiers in Immunology.

Anaphylaxis in referred pediatric patients: demographic and clinical features, triggers, and therapeutic approach

D. Bullens, M. Raes, L. D. De Swert, 2008, European Journal of Pediatrics.

COVID-19 Vaccination Safety and Tolerability in Patients Allegedly at High Risk for Immediate Hypersensitivity Reactions

D. Bullens, P. Vandenberghe, R. Schrijvers, 2022, Vaccines.

Van Wyk and Grumbach syndrome: an unusual form of precocious puberty

D. Bullens, K. Casteels, J. Toelen, 2014, Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.

Innate lymphoid cells in asthma: pathophysiological insights from murine models to human asthma phenotypes

S. Seys, D. Bullens, Anne-Charlotte Jonckheere, 2019, Current opinion in allergy and clinical immunology.

Congenital Rubella Syndrome After Maternal Reinfection

D. Bullens, K. Smets, P. Vanhaesebrouck, 2000, Clinical pediatrics.

P005 Restoration of Foxp3 regulatory T cells in blood correlates with clinical response to anti-TNF therapy for IBD

P. Rutgeerts, S. Vermeire, M. Ferrante, 2012 .

Anti–Tumor Necrosis Factor Therapy Restores Peripheral Blood B-cell Subsets and CD40 Expression in Inflammatory Bowel Diseases

P. Rutgeerts, S. Vermeire, M. Ferrante, 2015, Inflammatory bowel diseases.

The clinical and immunological basis of early food introduction in food allergy prevention

D. Bullens, R. Schrijvers, M. Diels, 2023, Frontiers in Allergy.

The Role of the IL23/IL17 Axis in Bronchiolitis Obliterans Syndrome After Lung Transplantation

G. Verleden, L. Dupont, W. Wuyts, 2008, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Nasal symptoms, epithelial injury and neurogenic inflammation in elite swimmers.

P. Hellings, V. Hox, S. Seys, 2018, Rhinology.

Tackling nasal symptoms in athletes: moving towards personalized medicine.

V. Hox, S. Seys, B. Steelant, 2021, Allergy.

Tackling nasal symptoms in athletes: Moving towards personalized medicine

V. Hox, S. Seys, B. Steelant, 2020, Allergy.

Cluster analysis of sputum cytokine-high profiles reveals diversity in T(h)2-high asthma patients

P. Hellings, S. Seys, J. Ceuppens, 2017, Respiratory Research.

Involvement of interleukin 18 in Crohn's disease: evidence from in vitro analysis of human gut inflammatory cells and from experimental colitis models

P. Rutgeerts, G. Van Assche, J. Ceuppens, 2004, Clinical and experimental immunology.

Airway inflammation in patients with chronic non-asthmatic cough

S. Seys, L. Dupont, D. Bullens, 2012, Thorax.

Analytical accuracy and user-friendliness of the Afinion point-of-care CRP test

D. Bullens, F. Buntinx, B. Aertgeerts, 2013, Journal of Clinical Pathology.

Prevalence and triggers of self-reported nasal hyperreactivity in adults with asthma

W. Fokkens, D. Larenas-Linnemann, I. Agache, 2020, The World Allergy Organization journal.

Measuring T cell cytokines in allergic upper and lower airway inflammation: can we move to the clinic?

D. Bullens, 2007, Inflammation & allergy drug targets.

Placental growth factor contributes to bronchial neutrophilic inflammation and edema in allergic asthma.

C. Dooms, P. Carmeliet, P. Hellings, 2012, American journal of respiratory cell and molecular biology.

Differential effects of intense exercise and pollution on the airways in a murine model

L. Dupont, D. Bullens, J. Vanoirbeek, 2021, Particle and fibre toxicology.

Haptoglobin deficiency facilitates the development of autoimmune inflammation

Wim Maes, Bert Verbinnen, J. Ceuppens, 2009, European journal of immunology.

Investigation of Sleep Quality and Sleep Disorders in Students of Medicine

J. E. Hansen, R. Casaburi, A. Malhotra, 2016 .

Do Meteorological Changes Have an Effect on The Occurence of Spontaneous Pneumothorax?

J. E. Hansen, R. Casaburi, A. Malhotra, 2020 .

Official journal of the Turkish Thoracic Society

Ankara, J. E. Hansen, R. Casaburi, 2018 .

Exposome mapping in chronic respiratory diseases: the added value of digital technology

S. Seys, L. Dupont, D. Bullens, 2021, Current opinion in allergy and clinical immunology.

Immunotherapy with subcutaneous immunogenic autologous tumor lysate increases murine glioblastoma survival

D. Bullens, S. V. Van Gool, B. Creyns, 2017, Scientific Reports.

Official journal of the Turkish Thoracic Society

J. E. Hansen, Hasan S. Yamin, R. Casaburi, 2018 .

Impaired barrier function in patients with house dust mite-induced allergic rhinitis is accompanied by decreased occludin and zonula occludens-1 expression.

P. Hellings, C. Akdis, S. Seys, 2016, The Journal of allergy and clinical immunology.

Low cord blood Foxp3/CD3γ mRNA ratios: a marker of increased risk for allergy development

D. Bullens, E. Dilissen, Ahmad Kasran, 2015, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Naive human T cells can be a source of IL‐4 during primary immune responses

D. Bullens, Bullens, Kasran, 1999, Clinical and experimental immunology.

Mechanisms of exercise‐induced bronchoconstriction in athletes: Current perspectives and future challenges

L. Delgado, M. Kowalski, S. Seys, 2018, Allergy.