A. A. Jensen

发表

Design, Synthesis, and Pharmacological Characterization of Heterobivalent Ligands for the Putative 5-HT2A/mGlu2 Receptor Complex.

C. B. Poulie, Na Liu, A. A. Jensen, 2020, Journal of medicinal chemistry.

Allosteric Modulation of an Excitatory Amino Acid Transporter: The Subtype-Selective Inhibitor UCPH-101 Exerts Sustained Inhibition of EAAT1 through an Intramonomeric Site in the Trimerization Domain

A. A. Jensen, L. Bunch, C. Fahlke, 2013, The Journal of Neuroscience.

Structure, pharmacology and therapeutic prospects of family C G-protein coupled receptors.

A. A. Jensen, P. Wellendorph, H. Bräuner‐Osborne, 2007, Current drug targets.

The dopamine D1 receptor family: structural and functional aspects.

A. A. Jensen, U. B. Pedersen, N. Din, 1996, Biochemical Society transactions.

Stereoselective chemoenzymatic synthesis of the four stereoisomers of l-2-(2-carboxycyclobutyl)glycine and pharmacological characterization at human excitatory amino acid transporter subtypes 1, 2, and 3.

T. Gefflaut, A. A. Jensen, L. Bunch, 2006, Journal of medicinal chemistry.

Allosteric modulation of G-protein coupled receptors.

A. A. Jensen, T. Spalding, Anders A Jensen, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Allosteric Modulation of the Calcium-Sensing Receptor

A. A. Jensen, H. Bräuner‐Osborne, A. Jensen, 2007, Current neuropharmacology.

Probing intermolecular protein-protein interactions in the calcium-sensing receptor homodimer using bioluminescence resonance energy transfer (BRET).

Hans Bräuner-Osborne, J. L. Hansen, A. A. Jensen, 2002, European journal of biochemistry.

The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization.

Peter Naur, Hans Bräuner-Osborne, P. Naur, 2009, Journal of medicinal chemistry.

Synthesis and biological activity of novel alpha-conotoxin analogues incorporating substituted proline derivatives.

T. Liljefors, Christian Skonberg, A. A. Jensen, 2009, Advances in experimental medicine and biology.

A Synthetic Combinatorial Strategy for Developing α-Conotoxin Analogs as Potent α7 Nicotinic Acetylcholine Receptor Antagonists*

Richard A Houghten, J. Medina-Franco, R. Houghten, 2009, The Journal of Biological Chemistry.

Strychnine and its mono- and dimeric analogues: a pharmaco-chemical perspective.

A. A. Jensen, D. Zlotos, Yasmine M Mandour, 2022, Natural product reports.

Discovery of Benzamide Analogues as a Novel Class of 5‐HT3 Receptor Agonists

J. Kehler, A. A. Jensen, B. Frølund, 2011, ChemMedChem.

25CN‐NBOH: A Selective Agonist for in vitro and in vivo Investigations of the Serotonin 2A Receptor

A. A. Jensen, J. Kristensen, Emil Märcher Rørsted, 2021, ChemMedChem.

Functional characterization of 5-HT1A and 5-HT1B serotonin receptor signaling through G-protein-activated inwardly rectifying K+ channels in a fluorescence-based membrane potential assay.

A. A. Jensen, Camilla Gadgaard, A. Jensen, 2020, Biochemical pharmacology.

Pharmacological characterization of human excitatory amino acid transporters EAAT1, EAAT2 and EAAT3 in a fluorescence-based membrane potential assay.

A. A. Jensen, H. Bräuner‐Osborne, A. Jensen, 2004, Biochemical pharmacology.

Structure – Activity Relationship Study of Selective Excitatory Amino Acid Transporter Subtype 1 ( EAAT 1 ) Inhibitor 2-Amino-4-( 4-methoxyphenyl )-7-( naphthalen-1-yl )-5-oxo-5 , 6 , 7 , 8-tetrahydro-4 H-chromene-3-carbonitrile ( UCPH-101 ) and Absolute Configurational Assignment Using Infrared and

H. Bohr, A. A. Jensen, L. Bunch, 2017 .

Structure-activity relationship study of selective excitatory amino acid transporter subtype 1 (EAAT1) inhibitor 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101) and absolute configurational assignment using infrared and vibrational circu

H. Bohr, A. A. Jensen, L. Bunch, 2012, Journal of medicinal chemistry.

Structure–Activity Relationship Study of Selective Excitatory Amino Acid Transporter Subtype

H. Bohr, A. A. Jensen, L. Bunch, 2012 .

11-Aminostrychnine and N-(Strychnine-11-yl)propionamide: Synthesis, Configuration, and Pharmacological Evaluation at Glycine Receptors.

U. Holzgrabe, C. Sotriffer, A. A. Jensen, 2019, Journal of natural products.

Copper and protons directly activate the zinc-activated channel.

S. Moss, T. Deeb, P. Davies, 2016, Biochemical pharmacology.

Discovery of α‐Substituted Imidazole‐4‐acetic Acid Analogues as a Novel Class of ρ1 γ‐Aminobutyric Acid Type A Receptor Antagonists with Effect on Retinal Vascular Tone

J. Kehler, C. Bundgaard, T. Bek, 2016, ChemMedChem.

Functional Characterization of the 1,5-Benzodiazepine Clobazam and Its Major Active Metabolite N-Desmethylclobazam at Human GABAA Receptors Expressed in Xenopus laevis Oocytes

A. A. Jensen, B. Ebert, H. Jensen, 2015, PloS one.

Investigation of the 2,5-dimethoxy motif in phenethylamine Serotonin 2A receptor agonists.

A. A. Jensen, J. Kristensen, A. Halberstadt, 2020, ACS chemical neuroscience.

Comparison of biophysical properties of α1β2 and α3β2 GABAA receptors in whole-cell patch-clamp electrophysiological recordings

A. A. Jensen, C. Villmann, E. Olander, 2020, PloS one.

From Methaqualone and Beyond: Structure-Activity Relationship of 6-, 7-, and 8-Substituted 2,3-Diphenyl-quinazolin-4(3H)-ones and in Silico Prediction of Putative Binding Modes of Quinazolin-4(3H)-ones as Positive Allosteric Modulators of GABAA Receptors.

A. A. Jensen, L. Bunch, Peng Wang, 2020, ACS chemical neuroscience.

Developing new 4-PIOL and 4-PHP analogues for photo-inactivation of γ-aminobutyric acid type A receptors.

A. A. Jensen, T. Smart, B. Frølund, 2019, ACS chemical neuroscience.

Pharmacological characterization of homobaclofen on wild type and mutant GABA(B)1b receptors coexpressed with the GABA(B)2 receptor.

P. Krogsgaard‐Larsen, A. A. Jensen, H. Bräuner‐Osborne, 2001, European journal of pharmacology.

Functional characterisation of homomeric ionotropic glutamate receptors GluR1-GluR6 in a fluorescence-based high throughput screening assay.

A. A. Jensen, H. Bräuner‐Osborne, Mette Strange, 2006, Combinatorial chemistry & high throughput screening.

Functional characterization of Tet-AMPA [tetrazolyl-2-amino-3-(3-hydroxy-5-methyl- 4-isoxazolyl)propionic acid] analogues at ionotropic glutamate receptors GluR1-GluR4. The molecular basis for the functional selectivity profile of 2-Bn-Tet-AMPA.

J. Greenwood, A. A. Jensen, R. Clausen, 2007, Journal of medicinal chemistry.

The selective 5-HT2A receptor agonist 25CN-NBOH: structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH.

A. A. Jensen, H. Bräuner‐Osborne, Martin Hansen, 2020, Biochemical pharmacology.

Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties.

D. Gloriam, P. Krogsgaard‐Larsen, A. A. Jensen, 2013, Journal of medicinal chemistry.

5-HT2A/5-HT2C Receptor Pharmacology and Intrinsic Clearance of N-Benzylphenethylamines Modified at the Primary Site of Metabolism.

J. Kehler, C. Bundgaard, A. A. Jensen, 2016, ACS chemical neuroscience.

5-Substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel gamma-aminobutyric acid(C) receptor agonists.

T. Liljefors, U. Kristiansen, P. Krogsgaard‐Larsen, 2007, Journal of Medicinal Chemistry.