Shobha Ghosh

发表

The mammalian amiloride‐insensitive non‐specific salt taste receptor is a vanilloid receptor‐1 variant

Shobha Ghosh, J. Bigbee, J. Desimone, 2004, The Journal of physiology.

Macrophage-specific transgenic expression of cholesteryl ester hydrolase attenuates hepatic lipid accumulation and also improves glucose tolerance in ob/ob mice.

K. Marqueen, Shobha Ghosh, Jinghua Bie, 2012, American journal of physiology. Endocrinology and metabolism.

Intestine‐specific expression of human chimeric intestinal alkaline phosphatase attenuates Western diet‐induced barrier dysfunction and glucose intolerance

S. Ghosh, Shobha Ghosh, Jing Wang, 2018, Physiological reports.

Nanomedicines for dysfunctional macrophage-associated diseases.

Shobha Ghosh, Hu Yang, Hongliang He, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Early steps in reverse cholesterol transport: cholesteryl ester hydrolase and other hydrolases

Shobha Ghosh, 2012, Current opinion in endocrinology, diabetes, and obesity.

Macrophage cholesterol homeostasis and metabolic diseases: critical role of cholesteryl ester mobilization

Shobha Ghosh, 2011, Expert review of cardiovascular therapy.

PPARgamma ligand attenuates PDGF-induced mesangial cell proliferation: role of MAP kinase.

S. Ghosh, V. Lyall, Shobha Ghosh, 2003, Kidney international.

Nanoparticle-based "Two-pronged" approach to regress atherosclerosis by simultaneous modulation of cholesterol influx and efflux.

Shobha Ghosh, Hu Yang, Jing Wang, 2020, Biomaterials.

Sodium butyrate ameliorates insulin resistance and renal failure in CKD rats by modulating intestinal permeability and mucin expression

S. Ghosh, Shobha Ghosh, T. Gehr, 2018, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Curcumin improves intestinal barrier function: modulation of intracellular signaling, and organization of tight junctions.

S. Ghosh, Shobha Ghosh, Jing Wang, 2017, American journal of physiology. Cell physiology.

Intracellular cholesterol transport proteins enhance hydrolysis of HDL-CEs and facilitate elimination of cholesterol into bile

Shobha Ghosh, Jinghua Bie, Jing Wang, 2016, Journal of Lipid Research.

Targeted PPARγ deficiency in alveolar macrophages disrupts surfactant catabolism

B. Barna, Shobha Ghosh, M. Kavuru, 2010, Journal of Lipid Research.

Targeted PPAR³ Deficiency In Alveolar Macrophages Disrupts Surfactant Catabolism

B. Barna, Shobha Ghosh, M. Kavuru, 2010, ATS 2010.

Impaired Delivery of Cholesterol Effluxed From Macrophages to Hepatocytes by Serum From CKD Patients May Underlie Increased Cardiovascular Disease Risk

Dave L Dixon, S. Carbone, Shobha Ghosh, 2019, Kidney international reports.

Improved Insulin Sensitivity in High Fat- and High Cholesterol-fed Ldlr−/− Mice with Macrophage-specific Transgenic Expression of Cholesteryl Ester Hydrolase

Shobha Ghosh, Jinghua Bie, Bin Zhao, 2010, The Journal of Biological Chemistry.

Astrocyte Elevated Gene-1 Regulates Macrophage Activation in Hepatocellular Carcinogenesis.

N. Mukhopadhyay, P. Fisher, M. Subler, 2018, Cancer research.

Genetic deletion of AEG-1 prevents hepatocarcinogenesis.

P. Fisher, M. Subler, J. Windle, 2014, Cancer research.

Hypoxia inducible factor-1: regulation by nitric oxide in posthypoxic microvascular endothelium.

Shobha Ghosh, A. Fowler, B. Fisher, 2005, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Human liver cholesteryl ester hydrolase: cloning, molecular characterization, and role in cellular cholesterol homeostasis.

Shobha Ghosh, Bin Zhao, R. Natarajan, 2005, Physiological genomics.

Astrocyte Elevated Gene-1 (AEG-1) Regulates Lipid Homeostasis*

P. Fisher, G. Sundaresan, M. Subler, 2015, The Journal of Biological Chemistry.

Over-Expression of Intestinal Alkaline Phosphatase Attenuates Atherosclerosis

S. Ghosh, Shobha Ghosh, Jing Wang, 2021, Circulation research.

Intestinal barrier function and metabolic/liver diseases

S. Ghosh, Shobha Ghosh, Jing Wang, 2020 .

Curcumin-mediated regulation of intestinal barrier function: The mechanism underlying its beneficial effects

S. Ghosh, Shobha Ghosh, Jing Wang, 2018, Tissue barriers.

Shobha Ghosh, R. Natarajan, W. McLean Grogan, 1997, Lipids.

Reoxygenating microvascular endothelium exhibits temporal dissociation of NF-kappaB and AP-1 activation.

Shobha Ghosh, A. Fowler, B. Fisher, 2002, Free radical biology & medicine.

Bolstering cholesteryl ester hydrolysis in liver: A hepatocyte-targeting gene delivery strategy for potential alleviation of atherosclerosis.

Shobha Ghosh, Hu Yang, Jing Wang, 2017, Biomaterials.

A novel role of astrocyte elevated gene‐1 (AEG‐1) in regulating nonalcoholic steatohepatitis (NASH)

N. Mukhopadhyay, P. Fisher, Yidong Chen, 2017, Hepatology.

Regulation of interleukin‐1 beta secretion from macrophages via modulation of potassium ion (K+) channel activity

S. Ghosh, Shobha Ghosh, Jing Wang, 2019, FEBS letters.

Role of cholesteryl ester hydrolase in atherosclerosis

Shobha Ghosh, Jinghua Bie, Bin Zhao, 2009 .

Stable overexpression of human macrophage cholesteryl ester hydrolase results in enhanced free cholesterol efflux from human THP1 macrophages.

Shobha Ghosh, Bin Zhao, Jingmei Song, 2007, American journal of physiology. Cell physiology.

Development of mannose functionalized dendrimeric nanoparticles for targeted delivery to macrophages: use of this platform to modulate atherosclerosis

Shobha Ghosh, Hu Yang, Quan Yuan, 2017, Translational research : the journal of laboratory and clinical medicine.

Oral Supplementation with Non-Absorbable Antibiotics or Curcumin Attenuates Western Diet-Induced Atherosclerosis and Glucose Intolerance in LDLR−/− Mice – Role of Intestinal Permeability and Macrophage Activation

S. Ghosh, Shobha Ghosh, Jinghua Bie, 2014, PloS one.

Activation of rat liver cholesterol ester hydrolase by cAMP-dependent protein kinase and protein kinase C

Shobha Ghosh, W. Grogan, 1989, Lipids.

Liver-specific transgenic expression of cholesteryl ester hydrolase reduces atherosclerosis in Ldlr−/− mice[S]

S. Ghosh, Shobha Ghosh, Quan Yuan, 2014, Journal of Lipid Research.

Liver-Specific Cholesteryl Ester Hydrolase Deficiency Attenuates Sterol Elimination in the Feces and Increases Atherosclerosis in Ldlr−/− Mice

S. Ghosh, K. Marqueen, Shobha Ghosh, 2013, Arteriosclerosis, thrombosis, and vascular biology.

Hepatic overexpression of cholesteryl ester hydrolase enhances cholesterol elimination and in vivo reverse cholesterol transport This work was supported by American Heart Association Grant 0755392U to S.G. Published, JLR Papers in Press, July 3, 2008.

Shobha Ghosh, Bin Zhao, Jingmei Song, 2008, Journal of Lipid Research.

Macrophage-specific transgenic expression of cholesteryl ester hydrolase significantly reduces atherosclerosis and lesion necrosis in Ldlr mice.

Shobha Ghosh, L. Rudel, Bin Zhao, 2007, The Journal of clinical investigation.

IMPROVED INSULIN SENSITIVITY IN HIGH-FAT HIGH-CHOLESTEROL FED LDLR-/- MICE WITH MACROPHAGE-SPECIFIC TRANSGENIC EXPRESSION OF CHOLESTERYL ESTER HYDROLASE: ROLE OF MACROPHAGE INFLAMMATION AND INFILTRATION INTO ADIPOSE TISSUE

Shobha Ghosh, Jinghua Bie, Bin Zhao, 2010 .

HMGB1 (High-Mobility Group Box-1): A Common Link Determining the Consequences of Tissue Injury, Sterile/Microbial and Low-Grade Chronic Inflammation.

S. Ghosh, Shobha Ghosh, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Hypercholesterolemia Enhances Tolerance to Lethal Systemic Hypoxia in Middle-Aged Mice: Possible Role of VEGF Downregulation in Brain

Anindita Das, Shobha Ghosh, Xiaoying Wang, 2006, Molecular and Cellular Biochemistry.

Mobilization of cytoplasmic CE droplets by overexpression of human macrophage cholesteryl ester hydrolase Published, JLR Papers in Press, July 1, 2003. DOI 10.1194/jlr.M300162-JLR200

Shobha Ghosh, L. Rudel, R. S. St. Clair, 2003, Journal of Lipid Research.

Separation and differential activation of rat liver cytosolic cholesteryl ester hydrolase, triglyceride lipase and retinyl palmitate hydrolase by cholestyramine and protein kinases

Shobha Ghosh, W. Grogan, M. Kounnas, 1990, Lipids.

Rapid three-step purification of a hepatic neutral cholesteryl ester hydrolase which is not the pancreatic enzyme

Shobha Ghosh, W. Grogan, 1991, Lipids.

Atherosclerotic lesion progression is attenuated by reconstitution with bone marrow from macrophage-specific cholesteryl ester hydrolase transgenic mice.

Shobha Ghosh, Jinghua Bie, Bin Zhao, 2011, American journal of physiology. Regulatory, integrative and comparative physiology.

Dietary Supplementation with Galactooligosaccharides Attenuates High-Fat, High-Cholesterol Diet-Induced Glucose Intolerance and Disruption of Colonic Mucin Layer in C57BL/6 Mice and Reduces Atherosclerosis in Ldlr-/- Mice.

S. Ghosh, Shobha Ghosh, Jing Wang, 2019, The Journal of nutrition.

Sodium butyrate ameliorates insulin resistance and renal failure in CKD rats by modulating intestinal permeability and mucin expression

S. Ghosh, Shobha Ghosh, T. Gehr, 2018, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

A novel vanilloid receptor-1 (VR-1) variant mammalian salt taste receptor.

J. Desimone, V. Lyall, T. Phan, 2005, Chemical senses.

Curcumin and Chronic Kidney Disease (CKD): Major Mode of Action through Stimulating Endogenous Intestinal Alkaline Phosphatase

S. Ghosh, Shobha Ghosh, T. Gehr, 2014, Molecules.

AEG-1 regulates retinoid X receptor and inhibits retinoid signaling.

N. Mukhopadhyay, P. Fisher, K. Shah, 2014, Cancer research.

Abstract 10870: Dietary Supplement Curcumin Reduces Inflammation and Significantly Improves Glucose Tolerance and Atherosclerosis in LDLR-/- Mice

S. Ghosh, Shobha Ghosh, Jinghua Bie, 2011 .

Intestinal Barrier Dysfunction, LPS Translocation, and Disease Development

S. Ghosh, Shobha Ghosh, Jing Wang, 2020, Journal of the Endocrine Society.

Leutusome: A Biomimetic Nanoplatform Integrating Plasma Membrane Components of Leukocytes and Tumor Cells for Remarkably Enhanced Solid Tumor Homing.

Shobha Ghosh, Hu Yang, Jing Wang, 2018, Nano letters.

Identifying important parameters in the inflammatory process with a mathematical model of immune cell influx and macrophage polarization

Marcella Torres, Jing Wang, Paul J Yannie, 2019, PLoS Comput. Biol..

Neutrophil Elastase Triggers the Release of Macrophage Extracellular Traps: Relevance to CF.

Shobha Ghosh, Adam M. Hawkridge, Shuo Zheng, 2021, American journal of respiratory cell and molecular biology.

Macrophage cholesteryl ester mobilization and atherosclerosis.

Shobha Ghosh, Jinghua Bie, Bin Zhao, 2010, Vascular pharmacology.

Cholesterol removal from plaques and elimination from the body: change in paradigm to reduce risk for heart disease

Shobha Ghosh, Quan Yuan, Jinghua Bie, 2014 .

Identification of a novel intracellular cholesteryl ester hydrolase (carboxylesterase 3) in human macrophages: compensatory increase in its expression after carboxylesterase 1 silencing.

Shobha Ghosh, Jinghua Bie, Bin Zhao, 2012, American journal of physiology. Cell physiology.

High Fat High Cholesterol Diet (Western Diet) Aggravates Atherosclerosis, Hyperglycemia and Renal Failure in Nephrectomized LDL Receptor Knockout Mice: Role of Intestine Derived Lipopolysaccharide

Shobha Ghosh, D. Sica, Samuel Righi, 2015, PloS one.

Macrophage Cholesterol Homeostasis and Atherogenesis: Critical Role of Intracellular Cholesteryl Ester Hydrolysis

Shobha Ghosh, 2012 .

Expression and cyclic variability of CYP3A4 and CYP3A7 isoforms in human endometrium and cervix during the menstrual cycle.

Shobha Ghosh, Shobha Ghosh, Douglas D Glover, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Cooperation between hepatic cholesteryl ester hydrolase and scavenger receptor BI for hydrolysis of HDL-CE

Shobha Ghosh, Quan Yuan, Jinghua Bie, 2013, Journal of Lipid Research.

Regulation of hepatic neutral cholesteryl ester hydrolase by hormones and changes in cholesterol flux.

P. Hylemon, Shobha Ghosh, W. Pandak, 1998, American journal of physiology. Gastrointestinal and liver physiology.

Sterol carrier protein-2 deficiency attenuates diet-induced dyslipidemia and atherosclerosis in mice

Shobha Ghosh, Jing Wang, Hongliang He, 2018, The Journal of Biological Chemistry.

Lipid metabolism, immunity and metabolic diseases

Shobha Ghosh, 2013 .

Neutrophil Elastase-Regulated Macrophage Sheddome/ Secretome and Phagocytic Failure.

Shobha Ghosh, Adam M. Hawkridge, Shuo Zheng, 2021, American Journal of Physiology - Lung cellular and Molecular Physiology.

Regulation of the rat neutral cytosolic cholesteryl ester hydrolase promoter by hormones and sterols: a role for nuclear factor-Y in the sterol-mediated response.

S. Ghosh, Shobha Ghosh, W. Grogan, 1999, Journal of lipid research.

Molecular cloning of the promoter for rat hepatic neutral cholesterol ester hydrolase: evidence for transcriptional regulation by sterols.

S. Ghosh, Shobha Ghosh, W. Grogan, 1998, Biochemical and biophysical research communications.

Cloning of the human cholesteryl ester hydrolase promoter: identification of functional peroxisomal proliferator-activated receptor responsive elements.

S. Ghosh, Shobha Ghosh, R. Natarajan, 2001, Biochemical and biophysical research communications.

Curcumin and enalapril ameliorate renal failure by antagonizing inflammation in 5/6 nephrectomized rats: role of phospholipase and cyclooxygenase.

Shobha Ghosh, D. Sica, S. Ghosh, 2012, American journal of physiology. Renal physiology.

Curcumin ameliorates renal failure in 5/6 nephrectomized rats: role of inflammation.

Shobha Ghosh, D. Sica, S. Ghosh, 2009, American journal of physiology. Renal physiology.

Important considerations for evaluating the data presented by Igarashi et al.

Shobha Ghosh, 2011, Circulation research.

Curcumin and enalapril ameliorate renal failure by antagonizing inflammation in 5/6 nephrectomized rats: role of phospholipase and cyclooxygenase.

Shobha Ghosh, T. Gehr, R. Krieg, 2012, American journal of physiology. Renal physiology.

Macrophage Cholesterol Homeostasis and Atherogenesis: Critical Role of Intracellular Cholesteryl Ester Hydrolysis

Shobha Ghosh, 2012 .

Curcumin as a potential therapeutic option for NAFLD and other metabolic diseases: need for establishing the underlying mechanism(s) of action

Shobha Ghosh, 2019, Hepatology International.