D. Larkin

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Aqueous Humor Alloreactive Cell Phenotypes, Cytokines and Chemokines in Corneal Allograft Rejection

Santa Jeremy Ono, T. Flynn, N. Mitchison, 2008, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Differential effects of costimulatory pathway modulation on corneal allograft survival.

D. Larkin, A. George, Martin P. Watson, 2006, Investigative ophthalmology & visual science.

Cytokine and chemokine expression kinetics after corneal transplantation.

D. Larkin, W. King, A. George, 2000, Transplantation.

Transplant rejection following endothelial keratoplasty and penetrating keratoplasty in the United Kingdom: incidence and survival.

D. Larkin, Y. Krishna, S. Kaye, 2015, American journal of ophthalmology.

Survey of Corneal Surgeons' Attitudes Regarding Keratoplasty Rejection Risk Associated With Vaccinations

D. Larkin, D. Lockington, J. Hjortdal, 2021, Cornea.

The Influence of Donor and Recipient Gender Incompatibility on Corneal Transplant Rejection and Failure

D. Larkin, V. Romano, S. Kaye, 2017, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Gene delivery to the corneal endothelium.

D. Larkin, P. Tan, W. King, 2000, American journal of respiratory and critical care medicine.

Corneal cross-linking versus standard care in children with keratoconus – a randomised, multicentre, observer-masked trial of efficacy and safety (KERALINK): a statistical analysis plan

C. Doré, C. Bunce, D. Larkin, 2020, Trials.

Effect of glaucoma on corneal graft survival according to indication for penetrating keratoplasty.

M. Batterbury, D. Larkin, S. Kaye, 2011, American journal of ophthalmology.

Differential Survival of Penetrating and Lamellar Transplants in Management of Failed Corneal Grafts

D. Larkin, Jonathan Aboshiha, Mark N. A. Jones, 2018, JAMA ophthalmology.

Diagnostic accuracy of microbial keratitis with in vivo scanning laser confocal microscopy

D. Larkin, J. Dart, K. Bibi, 2010, British Journal of Ophthalmology.

Local bioactive tumour necrosis factor (TNF) in corneal allotransplantation

D. Larkin, W. King, S. A. Rayner, 2000, Clinical and experimental immunology.

Suppression of the allogeneic response by the anti‐allergy drug N‐(3,4‐dimethoxycinnamonyl) anthranilic acid results from T‐cell cycle arrest

D. Larkin, A. George, J. Chai, 2013, Immunology.

Comparison of HIV-1 and EIAV-based lentiviral vectors in corneal transduction.

D. Larkin, P. Tan, G. Patton, 2005, Experimental eye research.

Activated polyamidoamine dendrimers, a non-viral vector for gene transfer to the corneal endothelium

J. Isaacs, H. Waldmann, D. Larkin, 1999, Gene Therapy.

Expression of the Chemokine Antagonist vMIP II Using a Non-Viral Vector Can Prolong Corneal Allograft Survival

D. Larkin, S. Beutelspacher, A. George, 2008, Transplantation.

Expression of Indoleamine 2,3‐Dioxygenase (IDO) by Endothelial Cells: Implications for the Control of Alloresponses

D. Larkin, S. Beutelspacher, P. H. Tan, 2006, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Identification of Therapeutic Targets of Inflammatory Monocyte Recruitment to Modulate the Allogeneic Injury to Donor Cornea.

B. Chain, M. Noursadeghi, D. Larkin, 2015, Investigative ophthalmology & visual science.

Dendritic cell modification as a route to inhibiting corneal graft rejection by the indirect pathway of allorecognition

D. Larkin, J. Harper, G. Lombardi, 2012, European journal of immunology.

3-hydroxykynurenine suppresses CD4+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival.

D. Larkin, A. George, H. Fu, 2011, Investigative ophthalmology & visual science.

EFFECT OF CORNEAL CROSS-LINKING vs STANDARD CARE ON KERATOCONUS PROGRESSION IN YOUNG PATIENTS: THE KERALINK RANDOMIZED CONTROLLED TRIAL.

S. Tuft, C. Doré, C. Bunce, 2021, Ophthalmology.

Effect of Corneal Cross-linking versus Standard Care on Keratoconus Progression in Young Patients

S. Tuft, C. Bunce, D. Larkin, 2021, Ophthalmology.

Modulation of hydrogen peroxide induced injury to corneal endothelium by virus mediated catalase gene transfer

J. Polak, P. Luthert, D. Larkin, 2002, The British journal of ophthalmology.

The effect of perioperative allergic conjunctivitis on corneal lymphangiogenesis after corneal transplantation

Santa Jeremy Ono, T. Flynn, D. Larkin, 2011, British Journal of Ophthalmology.

Characterization of dendritic cell phenotype in allergic conjunctiva: increased expression of FcɛRI, the high-affinity receptor for immunoglobulin E

Santa Jeremy Ono, D. Larkin, M. Ohbayashi, 2009, Eye.

Inflammatory cytokines induce apoptosis of corneal endothelium through nitric oxide.

D. Larkin, P. Sagoo, A. George, 2004, Investigative ophthalmology & visual science.

TNF receptor secretion after ex vivo adenoviral gene transfer to cornea and effect on in vivo graft survival.

D. Larkin, A. George, S. A. Rayner, 2001, Investigative ophthalmology & visual science.

A randomised, controlled, observer-masked trial of corneal cross-linking for progressive keratoconus in children: the KERALINK protocol

C. Doré, C. Bunce, D. Larkin, 2019, BMJ Open.

Modulation of costimulation by CD28 and CD154 alters the kinetics and cellular characteristics of corneal allograft rejection.

D. Larkin, P. Tan, A. George, 2003, Investigative ophthalmology & visual science.

Modulation of Costimulation by CD 28 and CD 154 Alters the Kinetics and Cellular Characteristics of Corneal Allograft Rejection

D. Larkin, P. Tan, A. George, 2003 .

Infiltrating inflammatory cell phenotypes and apoptosis in rejected human corneal allografts

I. Cree, D. Larkin, R. Alexander, 1997, Eye.

Immune Privilege of Corneal Allografts

D. Larkin, J. Niederkorn, F. Larkin, 2010, Ocular immunology and inflammation.

Center and surgeon effect on outcomes of endothelial keratoplasty versus penetrating keratoplasty in the United Kingdom.

D. Larkin, S. Kaye, Mark N. A. Jones, 2014, American journal of ophthalmology.

The host response in experimental corneal xenotransplantation

D. Larkin, K. Williams, 1995, Eye.

Identification and characterization of cells infiltrating the graft and aqueous humour in rat corneal allograft rejection

D. Larkin, S. Lightman, V. Calder, 1997, Clinical and experimental immunology.

Lipoadenofection-mediated gene delivery to the corneal endothelium: prospects for modulating graft rejection.

D. Larkin, H. Oral, A. George, 1998, Transplantation.

Immune modulation in corneal transplantation.

D. Larkin, A. George, H. Fu, 2008, Transplantation reviews.

Effect of administration of CTLA4-Ig as protein or cDNA on corneal allograft survival.

D. Larkin, S. Theoharis, W. King, 2002, Investigative ophthalmology & visual science.

Arginine depletion as a mechanism for the immune privilege of corneal allografts

D. Larkin, I. Müller, Adnan R. Khan, 2011, European journal of immunology.

Prospects for gene therapy in corneal disease

A. Jun, D. Larkin, 2003, Eye.

Adeno-associated and Herpes Simplex Viruses as Vectors for Gene Transfer to the Corneal Endothelium

D. Larkin, R. Coffin, M. de Alwis, 2000, Cornea.

Ex vivo adenovirus-mediated gene transfer and immunomodulatory protein production in human cornea

M. Dallman, M. Wood, D. Larkin, 1997, Gene Therapy.

Adenovirus-mediated gene delivery to the corneal endothelium.

N. Lemoine, D. Larkin, H. Oral, 1996, Transplantation.

Letter to the Editor in Response to Kim et al, "Effect of Histocompatibility Y Antigen Matching on Graft Survival in Primary Penetrating Keratoplasty."

D. Larkin, 2018, Cornea.

Modulation of Contact Inhibition by ZO-1/ZONAB Gene Transfer-A New Strategy to Increase the Endothelial Cell Density of Corneal Grafts.

A. Georgiadis, R. Ali, U. Luhmann, 2019, Investigative ophthalmology & visual science.

Clinical and confocal imaging findings in congenital corneal anaesthesia

D. Larkin, S. Hau, R. Guillon-Rolf, 2020, British Journal of Ophthalmology.

Post-operative Management

D. Larkin, S. Chow, D. Frank P. Larkin, 2016 .

Function of indoleamine 2,3‐dioxygenase in corneal allograft rejection and prolongation of allograft survival by over‐expression

D. Larkin, P. Tan, M. Mcclure, 2006, European journal of immunology.

Corneal Transplant Rejection

D. Larkin, T. Slegers, M. Daly, 2006 .

A new model of orthotopic penetrating corneal transplantation in the sheep: graft survival, phenotypes of graft-infiltrating cells and local cytokine production.

G. Russ, R. Mills, D. Larkin, 1999, Australian and New Zealand journal of ophthalmology.

A clinical, histopathological, and genetic study of Avellino corneal dystrophy in British families

A. Wagner, S. Bhattacharya, I. Cree, 2003, Journal of medical genetics.

Retreatment for significant regression after excimer laser photorefractive keratectomy. A prospective, randomized, masked trial.

D. Gartry, D. Larkin, A. Hill, 1998, Ophthalmology.

Sustained and widespread gene delivery to the corneal epithelium 1 via in situ transduction of limbal epithelial stem cells using lentiviral 2 and AAV vectors 3 4

Alexander J. Smith, D. Larkin, S. Kawasaki, 2018 .

Characterisation of the phenotype and function of monocyte-derived dendritic cells in allergic conjunctiva

Santa Jeremy Ono, D. Larkin, M. Ohbayashi, 2010, British Journal of Ophthalmology.

Graphical comparison of surgeon outcomes for the audit of a national corneal transplant registry (OTAG study 32)

S. Tuft, D. Larkin, J. Prydal, 2022, Eye.

Induction of replication in human corneal endothelial cells by E2F2 transcription factor cDNA transfer.

N. Joyce, D. Harris, R. Ali, 2005, Investigative ophthalmology & visual science.

Upregulation of chemokine expression in murine cornea due to mechanical trauma or endotoxin

D. Larkin, S. Beutelspacher, A. George, 2007, British Journal of Ophthalmology.

Update on Herpes simplex keratitis management

D. Larkin, D. Sibley, 2020, Eye.

A method for separation and staining of flat mounts of human corneal endothelium.

D. Larkin, M. Claesson, M. Elder, 2009, Acta ophthalmologica Scandinavica.

Treatment of Acanthamoeba keratitis with polyhexamethylene biguanide.

D. Larkin, S. Kilvington, J. Dart, 1991, Ophthalmology.

New Pharmacological Approaches for the Treatment of Neurotrophic Keratitis

D. Larkin, Su-yin Koay, 2022, Frontiers in Pharmacology.

Distribution of integrins αvβ5, αvβ3 and αv in normal human cornea: Possible implications in clinical and therapeutic adenoviral infection

D. Larkin, J. Gallop, A. George, 1998, Eye.

Quantitative alterations of the commensal eye bacteria in contact lens wear

D. Larkin, J. Leeming, 1991, Eye.

Optical coherence tomography angiography and indocyanine green angiography for corneal vascularisation

Marcus Ang, Dawn A Sim, Adnan Tufail, 2016, British Journal of Ophthalmology.

Fungal infection after endothelial keratoplasty: association with hypothermic corneal storage

S. Tuft, F. Kruse, D. Larkin, 2018, British Journal of Ophthalmology.

Descemet Membrane Endothelial Keratoplasty (DMEK) Graft Dislocation Into the Vitreous Cavity

L. da Cruz, D. Larkin, N. Brennan, 2018, Cornea.

The first successful full-thickness corneal transplant: a commentary on Eduard Zirm’s landmark paper of 1906

D. Larkin, W. Armitage, A. Tullo, 2006, British Journal of Ophthalmology.

Corneal Transplantation: The Forgotten Graft

D F P Larkin, D. Larkin, A J T George, 2004, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Quality of vision and graft thickness in deep anterior lamellar and penetrating corneal allografts.

S. Tuft, C. Bunce, D. Larkin, 2007, American journal of ophthalmology.

The impact of donor age and endothelial cell density on graft survival following penetrating keratoplasty

D. Larkin, S. Kaye, J. Prydal, 2015, British Journal of Ophthalmology.

Differential effects of primary disease and corneal vascularisation on corneal transplant rejection and survival

S. Tuft, D. Larkin, S. Kaye, 2019, British Journal of Ophthalmology.

Experimental gene transfer to the corneal endothelium.

R. Ali, D. Larkin, D. Kampik, 2012, Experimental eye research.

Graft Survival After Penetrating and Endothelial Keratoplasty in Iridocorneal Endothelial Syndrome.

S. Tuft, D. Larkin, E. Curnow, 2019, Cornea.

Sirolimus and mycophenolate as combination prophylaxis in corneal transplant recipients at high rejection risk.

D. Larkin, M. Chatel, 2010, American journal of ophthalmology.

KERATOPLASTY FOR KERATOCONUS IN YOUNG PATIENTS: DEMOGRAPHICS, CLINICAL FEATURES AND POST-TRANSPLANT OUTCOMES.

D. Larkin, Denise Wajnsztajn, C. Hopkinson, 2021, American journal of ophthalmology.

Corneal allograft rejection.

D. Larkin, 1994, The British journal of ophthalmology.

Corneal transplant surgery for keratoconus and the effect of surgeon experience on deep anterior lamellar keratoplasty outcomes.

D. Larkin, S. Kaye, Sajjad Ahmad, 2014, American journal of ophthalmology.

Centre-Specific Variation in Corneal Transplant Outcomes in the United Kingdom

D. Larkin, L. Mumford, Mark N. A. Jones, 2011, Transplantation.

Effect of allergic conjunctival inflammation on the allogeneic response to donor cornea.

Santa Jeremy Ono, T. Flynn, D. Larkin, 2007, Investigative ophthalmology & visual science.

Characteristics of endothelial corneal transplant rejection following immunisation with SARS-CoV-2 messenger RNA vaccine

D. Larkin, Ji-Peng Olivia Li, M. Phylactou, 2021, British Journal of Ophthalmology.

Longitudinal changes in corneal leucocyte density in vivo following transplantation

D. Larkin, C. Thaung, S. Hau, 2018, British Journal of Ophthalmology.

Corneal transplantation for herpes simplex keratitis

D. Larkin, 1998, British Journal of Ophthalmology.

Effect of overexpressing the transcription factor E2F2 on cell cycle progression in rabbit corneal endothelial cells.

N. Joyce, D. Harris, R. Ali, 2004, Investigative ophthalmology & visual science.

Response to Correspondence From Mohamed-Noriega et al.

D. Larkin, L. Mumford, Mark N. A. Jones, 2011 .

A randomised placebo-controlled trial of topical steroid in presumed viral conjunctivitis

C. Bunce, A. Khawaja, D. Larkin, 2011, British Journal of Ophthalmology.

Cell subpopulations in failed human corneal grafts

D. Larkin, 2000, The British journal of ophthalmology.

Cornea and External Eye Disease

D. F. P. Larkin, Thomas Reinhard, D. Larkin, 2006 .

Sustained and Widespread Gene Delivery to the Corneal Epithelium via In Situ Transduction of Limbal Epithelial Stem Cells, Using Lentiviral and Adeno-Associated Viral Vectors.

R. Ali, Alexander J. Smith, D. Larkin, 2018, Human gene therapy.

Use of ultrasonic pachymetry for measurement of changes in corneal thickness in mouse corneal transplant rejection

Santa Jeremy Ono, T. Flynn, D. Larkin, 2009, British Journal of Ophthalmology.

Gene transfer to ex vivo stored corneas.

D. Larkin, H. Oral, Z. Fehérvári, 1997, Cornea.

Influence of Socioeconomic Deprivation on Visual Acuity in Patients Undergoing Corneal Transplantation

D. Larkin, S. Robbie, Mark N. A. Jones, 2018, Cornea.

A clinical, histopathological, and genetic study of Avellino corneal dystrophy in British families

S. Bhattacharya, I. Cree, D. Larkin, 2003 .

EXPERIMENTAL ORTHOTOPIC CORNEAL XENOTRANSPLANTATION IN THE RAT MECHANISMS OF GRAFT REJECTION

D. Larkin, K. Williams, S. Standfield, 1995, Transplantation.

Medical Management of Blepharokeratoconjunctivitis in Children: A Delphi Consensus.

S. Tuft, D. Larkin, M. Hingorani, 2017, Journal of pediatric ophthalmology and strabismus.

Lipid-mediated enhancement of transfection by a nonviral integrin-targeting vector.

R. Levinsky, C. Mailhos, R. Ali, 1998, Human gene therapy.

Modulation of human dendritic-cell function following transduction with viral vectors: implications for gene therapy.

D. Larkin, P. Tan, G. Lombardi, 2005, Blood.

In situ regeneration of retinal pigment epithelium by gene transfer of E2F2: a potential strategy for treatment of macular degenerations

J. Greenwood, R. Ali, Y. Durán, 2017, Gene Therapy.

Factors leading to lens implant decentration and exchange

M. Tappin, D. Larkin, 2000, Eye.

High response rates with single-agent belantamab mafodotin in relapsed systemic AL amyloidosis

C. Kyriakou, D. Larkin, A. Wechalekar, 2022, Blood Cancer Journal.

Graphical comparison of surgeon outcomes for the audit of a national corneal transplant registry (OTAG study 32)

S. Tuft, D. Larkin, J. Prydal, 2022, Eye.

Surgical innovation in ophthalmology: challenges and opportunities

D. Larkin, A. Azuara-Blanco, G. Gazzard, 2022, Eye.

Antibody targeted gene transfer to endothelium

D F P Larkin, D. Larkin, M. Manunta, 2003, The journal of gene medicine.

Immune modulation in corneal transplantation.

D. Larkin, A. George, H. Fu, 2008, Transplantation reviews.

Pulsed oral corticosteroids for the treatment of vernal and atopic keratoconjunctivitis: a management plan

S. Tuft, D. Larkin, M. Hingorani, 2020, Eye.

Diagnosis and management of keratoconus in the paediatric age group: a review of current evidence.

D. Larkin, Liam D Price, 2023, Eye.

Longitudinal Changes to Tight Junction Expression and Endothelial Cell Integrity in a Mouse Model of Sterile Corneal Inflammation.

D. Larkin, 2016, Investigative ophthalmology & visual science.