B. Hall

发表

Developmental Variation in Rab11-Dependent Trafficking in Trypanosoma brucei

Mark C. Field, D. Goulding, B. Hall, 2005, Eukaryotic Cell.

An Essential Type I Nitroreductase from Leishmania major Can Be Used to Activate Leishmanicidal Prodrugs

B. Hall, A. Voak, K. Seifert, 2013, The Journal of Biological Chemistry.

Targeting the Substrate Preference of a Type I Nitroreductase To Develop Antitrypanosomal Quinone-Based Prodrugs

B. Hall, S. Wilkinson, E. Meredith, 2012, Antimicrobial Agents and Chemotherapy.

Mycolactone enhances the Ca leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca permeable state

A. Cavalié, V. Helms, B. Hall, 2021 .

Mycolactone enhances the Ca2+ leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca2+ permeable state

A. Cavalié, V. Helms, B. Hall, 2021, bioRxiv.

Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity

N. Ktistakis, B. Hall, G. Pluschke, 2021, Autophagy.

Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4

J. Taunton, B. Hall, R. Wek, 2018, Cell Death & Disease.

Inhibition of Sec 61-dependent translocation by mycolactone 1 uncouples the integrated stress response from ER stress , driving 2 cytotoxicity via translational activation of ATF 4 3 4

J. Taunton, B. Hall, A. Willis, 2018 .

The role of genomic location and flanking 3′UTR in the generation of functional levels of variant surface glycoprotein in Trypanosoma brucei

G. Rudenko, B. Hall, Cher-Pheng Ooi, 2017, Molecular microbiology.

TbVps34, the Trypanosome Orthologue of Vps34, Is Required for Golgi Complex Segregation*

Mark C. Field, D. Goulding, B. Hall, 2006, Journal of Biological Chemistry.

Trypanosoma brucei Rab 11-Dependent Trafficking in Developmental Variation in

Mark C. Field, D. Goulding, B. Hall, 2005 .

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

New Approaches to the Microscopic Imaging of Trypanosoma brucei

Mark C. Field, D. Goulding, G. Morgan, 2004, Microscopy and Microanalysis.

Structure of the Inhibited State of the Sec Translocon

P. Biggin, B. Hall, P. Mayerhofer, 2020, Molecular cell.

Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1β, are linked to fibrin formation in Buruli ulcer lesions

B. Hall, G. Pluschke, L. T. Hsieh, 2022, PLoS pathogens.

Rab5 and Rab11 mediate transferrin and anti-variant surface glycoprotein antibody recycling in Trypanosoma brucei.

Mark C. Field, B. Hall, A. Pal, 2003, The Biochemical journal.

Differential Endocytic Functions ofTrypanosoma brucei Rab5 Isoforms Reveal a Glycosylphosphatidylinositol-specific Endosomal Pathway*

Mark C. Field, H. Field, D. Nesbeth, 2002, The Journal of Biological Chemistry.

Synthesis and structure-activity relationships of nitrobenzyl phosphoramide mustards as nitroreductase-activated prodrugs.

P. Searle, B. Hall, S. Wilkinson, 2011, Bioorganic & medicinal chemistry letters.

Dynamic colocalization of 2 simultaneously active VSG expression sites within a single expression-site body in Trypanosoma brucei

P. Myler, G. Rudenko, B. Hall, 2019, Proceedings of the National Academy of Sciences.

Two major tyrosine protein kinases of resting human T lymphocytes are down‐regulated following mitotic stimulation

A. Hoffbrand, R. Wickremasinghe, B. Hall, 1987, FEBS letters.

Nifurtimox Activation by Trypanosomal Type I Nitroreductases Generates Cytotoxic Nitrile Metabolites*

B. Hall, S. Wilkinson, C. Bot, 2011, The Journal of Biological Chemistry.

Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions

C. Esmon, B. Hall, Hua-Lin Wu, 2015, PLoS pathogens.

Trypanocidal activity of nitroaromatic prodrugs: current treatments and future perspectives.

B. Hall, S. Wilkinson, J. Kelly, 2011, Current topics in medicinal chemistry.

Exploiting the Drug-Activating Properties of a Novel Trypanosomal Nitroreductase

B. Hall, S. Wilkinson, Longqin Hu, 2009, Antimicrobial Agents and Chemotherapy.

Synthesis and anti-parasitic activity of a novel quinolinone-chalcone series.

B. Hall, A. Detsi, S. Wilkinson, 2013, Bioorganic & medicinal chemistry letters.

Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation

James Inglese, S. High, C. Demangel, 2019, Journal of the American Chemical Society.

Modulation of protein kinase C activity in Plasmodium falciparum-infected erythrocytes.

B. Hall, G. Targett, O. Daramola, 1997, Blood.

Activation of Benznidazole by Trypanosomal Type I Nitroreductases Results in Glyoxal Formation

B. Hall, S. Wilkinson, 2011, Antimicrobial Agents and Chemotherapy.

Evaluating 5-Nitrofurans as Trypanocidal Agents

B. Hall, S. Wilkinson, H. Cerecetto, 2013, Antimicrobial Agents and Chemotherapy.

Trypanocidal Activity of Aziridinyl Nitrobenzamide Prodrugs

B. Hall, N. Helsby, S. Wilkinson, 2010, Antimicrobial Agents and Chemotherapy.

Trypanocidal Activity of Aziridinyl Nitrobenzamide Prodrugs (cid:1)

B. Hall, N. Helsby, S. Wilkinson, 2010 .

Megazol and its bioisostere 4H-1,2,4-triazole: comparing the trypanocidal, cytotoxic and genotoxic activities and their in vitro and in silico interactions with the Trypanosoma brucei nitroreductase enzyme

B. Hall, S. Wilkinson, E. Caffarena, 2014, Memorias do Instituto Oswaldo Cruz.

Agents5-Nitrofurans as Trypanocidal

B. Hall, S. Wilkinson, H. Cerecetto, 2013 .

Benznidazole-Resistance in Trypanosoma cruzi Is a Readily Acquired Trait That Can Arise Independently in a Single Population

B. Hall, O. Triana-Chávez, S. Wilkinson, 2012, The Journal of infectious diseases.

Distinct drug-resistant Trypanosoma cruzi clones can arise independently in a single population undergoing benznidazole-selection

B. Hall, O. Triana-Chávez, S. Wilkinson, 2011 .

Multiple tyrosine protein kinases structurally related to p56 lck are down-regulated following mitogenic stimulation of human T lymphocytes.

A. Hoffbrand, R. Wickremasinghe, B. Hall, 1990, Biochemical and biophysical research communications.

A Model for Sequestration of the Transmission Stages of Plasmodium falciparum: Adhesion of Gametocyte-Infected Erythrocytes to Human Bone Marrow Cells

B. Hall, J. Obiero, C. Sutherland, 2000, Infection and Immunity.

Pleiotropic molecular effects of the Mycobacterium ulcerans virulence factor mycolactone underlying the cell death and immunosuppression seen in Buruli ulcer.

Rachel Simmonds, B. Hall, Belinda Hall, 2014, Biochemical Society transactions.

The One That Got Away: How Macrophage-Derived IL-1β Escapes the Mycolactone-Dependent Sec61 Blockade in Buruli Ulcer

B. Hall, S. Sacre, L. T. Hsieh, 2022, Frontiers in Immunology.

Mycobacterium ulcerans and Buruli Ulcer

B. Hall, M. Benbow, L. Mosi, 2015 .

Mycolactone causes catastrophic Sec61-dependent loss of the endothelial glycocalyx and basement membrane: a new indirect mechanism driving tissue necrosis in Mycobacterium ulcerans infection

B. Hall, Y. Umrania, M. Deery, 2023, bioRxiv.

TbSAP is a novel chromatin protein repressing metacyclic variant surface glycoprotein expression sites in bloodstream form Trypanosoma brucei

B. Wickstead, G. Rudenko, B. Hall, 2021, Nucleic acids research.

Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation

R. Parker, B. Hall, A. Ruggieri, 2020, PLoS pathogens.

Norovirus infection results in assembly of virus-specific G3BP1 granules and evasion of eIF2α signaling

R. Parker, B. Hall, A. Ruggieri, 2018, bioRxiv.

Murine Norovirus Infection Results in Anti-inflammatory Response Downstream of Amino Acid Depletion in Macrophages

D. Beste, B. Hall, I. Goodfellow, 2021, Journal of virology.

Trypanosoma brucei: TbRAB4 regulates membrane recycling and expression of surface proteins in procyclic forms.

Mark C. Field, D. Goulding, B. Hall, 2005, Experimental parasitology.

Rab4 Is an Essential Regulator of Lysosomal Trafficking in Trypanosomes*

Mark C. Field, D. Goulding, B. Hall, 2004, Journal of Biological Chemistry.

The endocytic apparatus of the kinetoplastida. Part II: machinery and components of the system.

Mark C. Field, M. Carrington, G. Morgan, 2002, Trends in parasitology.

The kinetoplastida endocytic apparatus. Part I: a dynamic system for nutrition and evasion of host defences.

Mark C. Field, M. Carrington, G. Morgan, 2002, Trends in parasitology.

Dual Role for Transforming Growth Factor β-Dependent Signaling in Trypanosoma cruzi Infection of Mammalian Cells

B. Hall, M. Pereira, 2000, Infection and Immunity.

The Pathogenic Mechanism of the Mycobacterium ulcerans Virulence Factor, Mycolactone, Depends on Blockade of Protein Translocation into the ER

Michael McKenna, Anne E. Willis, S. High, 2014, PLoS pathogens.

Synthesis, Biological Evaluation and Docking Studies of Ring-Opened Analogues of Ipomoeassin F

S. High, V. Helms, B. Hall, 2022, Molecules.

Biology-directed and in silico -aided design liberates a potent, simplified and ipomoeassin-F-derived Sec61 inhibitor

S. High, V. Helms, B. Hall, 2022 .

Cell-specific activation of nuclear factor-kappaB by the parasite Trypanosoma cruzi promotes resistance to intracellular infection.

W. Tam, B. Hall, R. Sen, 2000, Molecular biology of the cell.

Evidence for a non-LDL-mediated entry route for the trypanocidal drug suramin in Trypanosoma brucei.

Mark C. Field, B. Hall, A. Pal, 2002, Molecular and biochemical parasitology.

Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4

J. Taunton, B. Hall, R. Wek, 2018, Cell Death & Disease.

Both of the Rab5 subfamily small GTPases of Trypanosoma brucei are essential and required for endocytosis.

Mark C. Field, D. Goulding, B. Hall, 2004, Molecular and biochemical parasitology.

Plasmodium falciparum gametocyte adhesion to C32 cells via CD36 is inhibited by antibodies to modified band 3

B. Hall, G. Targett, N. Rogers, 1996, Infection and immunity.

CD36 and intercellular adhesion molecule 1 mediate adhesion of developing Plasmodium falciparum gametocytes

B. Hall, G. Targett, O. Daramola, 1996, Infection and immunity.

Mycolactone enhances the Ca2+ leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca2+ permeable state

A. Cavalié, V. Helms, B. Hall, 2021, Biochemical Journal.

Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation.

R. Parker, B. Hall, A. Ruggieri, 2020 .

An Essential Type I Nitroreductase from Leishmania major Can Be Used to Activate Leishmanicidal Prodrugs

B. Hall, A. Voak, K. Seifert, 2013, The Journal of Biological Chemistry.

Murine Norovirus infection results in anti-inflammatory response downstream of amino acids depletion in macrophages

D. Beste, B. Hall, I. Goodfellow, 2021, bioRxiv.

Dynamic colocalization of 2 simultaneously active VSG expression sites within a single expression-site body in Trypanosoma brucei

P. Myler, G. Rudenko, B. Hall, 2019, Proceedings of the National Academy of Sciences.