M. Vetting

发表

Discovery of Function in the Enolase Superfamily: d-Mannonate and d-Gluconate Dehydratases in the d-Mannonate Dehydratase Subgroup

Steven C. Almo, Matthew W. Vetting, Ronald D. Seidel, 2014, Biochemistry.

Crystallization of a pentapeptide-repeat protein by reductive cyclic pentylation of free amines with glutaraldehyde.

J. Blanchard, M. Vetting, S. Hegde, 2009, Acta crystallographica. Section D, Biological crystallography.

Structure of human phosphatidylcholine transfer protein in complex with its ligand

M. Vetting, K. Rajashankar, Diana S. Agate, 2002, Nature Structural Biology.

Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily

Shoshana D. Brown, P. Babbitt, J. Gerlt, 2012, Proceedings of the National Academy of Sciences.

Large-Scale Determination of Sequence, Structure, and Function Relationships in Cytosolic Glutathione Transferases across the Biosphere

Richard N. Armstrong, Patricia C. Babbitt, Eyal Akiva, 2014, PLoS biology.

Biophysical analyses of designed and selected mutants of protocatechuate 3,4-dioxygenase1.

D. Ohlendorf, M. Vetting, C. A. Earhart, 2004, Annual review of microbiology.

Structural and Biochemical Analysis of the Pentapeptide Repeat Protein EfsQnr, a Potent DNA Gyrase Inhibitor

J. Blanchard, M. Vetting, A. Maxwell, 2010, Antimicrobial Agents and Chemotherapy.

Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid

Matthew W Vetting, Argyrides Argyrou, J. Blanchard, 2006, Nature Structural &Molecular Biology.

Structure of serine acetyltransferase in complexes with CoA and its cysteine feedback inhibitor.

M. Vetting, S. Roderick, L. R. Olsen, 2004, Biochemistry.

ATP-binding Cassette (ABC) Transport System Solute-binding Protein-guided Identification of Novel d-Altritol and Galactitol Catabolic Pathways in Agrobacterium tumefaciens C58*

J. Gerlt, S. Almo, D. Wichelecki, 2015, The Journal of Biological Chemistry.

Structures and mechanisms of the mycothiol biosynthetic enzymes.

J. Blanchard, M. Vetting, F. Fan, 2009, Current opinion in chemical biology.

Novel Metabolic Pathways and Regulons for Hexuronate Utilization in Proteobacteria

J. Gerlt, S. Almo, D. Rodionov, 2018, Journal of bacteriology.

ATP-binding Cassette (ABC) Transport System Solute-binding Protein-guided Identification of Novel D -Altritol and Galactitol Catabolic Pathways in Agrobacterium tumefaciens

J. Gerlt, S. Almo, D. Wichelecki, 2020 .

The Structure and Mechanism of the Mycobacterium tuberculosis Cyclodityrosine Synthetase

J. Blanchard, M. Vetting, S. Hegde, 2010, Nature chemical biology.

Crystallographic Comparison of Manganese- and Iron-Dependent Homoprotocatechuate 2,3-Dioxygenases

L. Wackett, D. Ohlendorf, L. Que, 2004, Journal of bacteriology.

Mechanistic and structural analysis of human spermidine/spermine N1-acetyltransferase.

Matthew W Vetting, J. Blanchard, M. Vetting, 2007, Biochemistry.

Roles of the equatorial tyrosyl iron ligand of protocatechuate 3,4-dioxygenase in catalysis.

D. Ohlendorf, D. Burk, J. Lipscomb, 2005, Biochemistry.

Structure of the E. coli bifunctional GlmU acetyltransferase active site with substrates and products

M. Vetting, S. Roderick, L. R. Olsen, 2007, Protein science : a publication of the Protein Society.

Structure of QnrB1, a Plasmid-mediated Fluoroquinolone Resistance Factor*

G. Jacoby, J. Blanchard, D. Hooper, 2011, The Journal of Biological Chemistry.

Pentapeptide repeat proteins.

A. Fiser, J. Fajardo, J. Blanchard, 2006, Biochemistry.

Crystal structure of the Streptococcus pneumoniae mevalonate kinase in complex with diphosphomevalonate

J. Andreassi, T. Leyh, M. Vetting, 2007, Protein science : a publication of the Protein Society.

Structure of catechol 1,2-dioxygenase from Pseudomonas arvilla.

D. Ohlendorf, L. Que, M. Vetting, 2005, Biochemical and biophysical research communications.

The Active Site of O-Acetylserine Sulfhydrylase Is the Anchor Point for Bienzyme Complex Formation with Serine Acetyltransferase

M. Vetting, S. Roderick, Bin Huang, 2005, Journal of bacteriology.

Characterization of a New Member of the Flavoprotein Disulfide Reductase Family of Enzymes from Mycobacterium tuberculosis*

J. Blanchard, M. Vetting, A. Argyrou, 2004, Journal of Biological Chemistry.

Kinetic and structural analysis of bisubstrate inhibition of the Salmonella enterica aminoglycoside 6'-N-acetyltransferase.

F. Gao, J. Blanchard, M. Vetting, 2008, Biochemistry.

Purification, crystallization and structural elucidation of D-galactaro-1,4-lactone cycloisomerase from Agrobacterium tumefaciens involved in pectin degradation.

J. Gerlt, S. Almo, M. Vetting, 2016, Acta crystallographica. Section F, Structural biology communications.

Structural and Enzymatic Analysis of MshA from Corynebacterium glutamicum

J. Blanchard, M. Vetting, P. Frantom, 2008, Journal of Biological Chemistry.

Structure and functions of the GNAT superfamily of acetyltransferases.

J. Blanchard, M. Vetting, S. Magnet, 2005, Archives of biochemistry and biophysics.

Experimental Strategies for Functional Annotation and Metabolism Discovery: Targeted Screening of Solute Binding Proteins and Unbiased Panning of Metabolomes

Ronald J. Quinn, Steven C. Almo, Matthew P. Jacobson, 2014, Biochemistry.

Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars

Matthew P Jacobson, Suwen Zhao, Brian San Francisco, 2016, Proceedings of the National Academy of Sciences.

A Fluoroquinolone Resistance Protein from Mycobacterium tuberculosis That Mimics DNA

Anthony Maxwell, Subray S. Hegde, Steven L. Roderick, 2005, Science.

Prediction of enzymatic pathways by integrative pathway mapping

Henry Lin, Andrej Sali, Matthew P Jacobson, 2018, eLife.

A unique cis-3-hydroxy-l-proline dehydratase in the enolase superfamily.

J. Gerlt, S. Almo, M. Jacobson, 2015, Journal of the American Chemical Society.

Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks

Eyal Akiva, Matthew P Jacobson, Suwen Zhao, 2014, eLife.

A bacterial acetyltransferase capable of regioselective N-acetylation of antibiotics and histones.

J. Blanchard, M. Vetting, S. Magnet, 2004, Chemistry & biology.

Functional assignment of multiple catabolic pathways for d-apiose

Steven C. Almo, Hua Huang, Matthew W. Vetting, 2018, Nature Chemical Biology.

Structure of an ABC transporter solute-binding protein specific for the amino sugars glucosamine and galactosamine.

J. Gerlt, S. Almo, M. Vetting, 2016, Acta crystallographica. Section F, Structural biology communications.

Crystal structure of RimI from Salmonella typhimurium LT2, the GNAT responsible for Nα‐acetylation of ribosomal protein S18

J. Blanchard, M. Vetting, Michael Yu, 2008, Protein science : a publication of the Protein Society.

A Novel Dimeric Structure of the RimL Nα-acetyltransferase from Salmonella typhimurium*

J. Blanchard, M. Vetting, S. Roderick, 2005, Journal of Biological Chemistry.

Discovery of new enzymes and metabolic pathways using structure and genome context

Ritesh Kumar, Patricia C. Babbitt, Steven C. Almo, 2016 .

Prospecting for Unannotated Enzymes: Discovery of a 3′,5′-Nucleotide Bisphosphate Phosphatase within the Amidohydrolase Superfamily

S. Almo, F. Raushel, M. Vetting, 2014, Biochemistry.

The 1.8 A crystal structure of catechol 1,2-dioxygenase reveals a novel hydrophobic helical zipper as a subunit linker.

D. Ohlendorf, M. Vetting, D H Ohlendorf, 2000, Structure.

Structure of the ternary complex of phosphomevalonate kinase: the enzyme and its family.

J. Andreassi, T. Leyh, M. Vetting, 2009, Biochemistry.

Protocatechuate 3,4-Dioxygenase

D. Ohlendorf, M. Vetting, 2006 .

A novel bifunctional transcriptional regulator of riboflavin metabolism in Archaea

Steven C. Almo, Dmitry A. Rodionov, Matthew W. Vetting, 2017, Nucleic acids research.

Pentapeptide-repeat proteins that act as topoisomerase poison resistance factors have a common dimer interface.

J. Blanchard, M. Vetting, S. Hegde, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N‐acetyltransferases

J. Blanchard, M. Vetting, Michael Yu, 2003, Protein science : a publication of the Protein Society.

Evolution of Enzymatic Activities in the Enolase Superfamily: Galactarate Dehydratase III from Agrobacterium tumefaciens C58

Steven C. Almo, Matthew P. Jacobson, Chakrapani Kalyanaraman, 2014, Biochemistry.

Galactaro δ-Lactone Isomerase: Lactone Isomerization by a Member of the Amidohydrolase Superfamily

J. Gerlt, S. Almo, M. Vetting, 2014, Biochemistry.

Structure-guided discovery of new deaminase enzymes.

Daniel S. Hitchcock, A. Sali, B. Shoichet, 2013, Journal of the American Chemical Society.

Structure of Acinetobacter strain ADP1 protocatechuate 3, 4-dioxygenase at 2.2 A resolution: implications for the mechanism of an intradiol dioxygenase.

D. Ohlendorf, M. Vetting, D. D'Argenio, 2000, Biochemistry.

Mechanistic and structural analysis of aminoglycoside N-acetyltransferase AAC(6')-Ib and its bifunctional, fluoroquinolone-active AAC(6')-Ib-cr variant.

G. Jacoby, J. Blanchard, D. Hooper, 2008, Biochemistry.

The 1.6 A crystal structure of Mycobacterium smegmatis MshC: the penultimate enzyme in the mycothiol biosynthetic pathway.

J. Blanchard, M. Vetting, L. Tremblay, 2008, Biochemistry.

The Substrate-induced Conformational Change of Mycobacterium tuberculosis Mycothiol Synthase*

J. Blanchard, M. Vetting, Michael Yu, 2006, Journal of Biological Chemistry.

Discovery of new enzymes and metabolic pathways using structure and genome context

Shoshana D. Brown, P. Babbitt, J. Gerlt, 2013, Nature.

Prediction of enzymatic pathways by integrative pathway mapping

Matthew J. O’Meara, Daniel Russel, A. Sali, 2018, eLife.

Prediction and Biochemical Demonstration of a Catabolic Pathway for the Osmoprotectant Proline Betaine

J. Gerlt, S. Almo, M. Jacobson, 2014, mBio.

A General Strategy for the Discovery of Metabolic Pathways: d-Threitol, l-Threitol, and Erythritol Utilization in Mycobacterium smegmatis.

Hua Huang, Matthew W Vetting, Steven C Almo, 2015, Journal of the American Chemical Society.

Aminoglycoside 2′-N-acetyltransferase from Mycobacterium tuberculosis in complex with coenzyme A and aminoglycoside substrates

J. Blanchard, M. Vetting, S. Hegde, 2002, Nature Structural Biology.

Structure-guided discovery of new deaminase enzymes.

Daniel S. Hitchcock, A. Sali, B. Shoichet, 2013, Journal of the American Chemical Society.

Discovery of an L-fucono-1,5-lactonase from cog3618 of the amidohydrolase superfamily.

Steven C Almo, S. Almo, F. Raushel, 2013, Biochemistry.

Structural characterization of the fusion of two pentapeptide repeat proteins, Np275 and Np276, from Nostoc punctiforme: Resurrection of an ancestral protein

J. Blanchard, M. Vetting, S. Hegde, 2007, Protein science : a publication of the Protein Society.

Crystallization and preliminary X-ray analysis of protocatechuate 3,4-dioxygenase from Acinetobacter calcoaceticus.

D. Ohlendorf, M. Vetting, C. A. Earhart, 1994, Journal of molecular biology.

New insight into the mechanism of action of and resistance to isoniazid: interaction of Mycobacterium tuberculosis enoyl-ACP reductase with INH-NADP.

Matthew W Vetting, Argyrides Argyrou, J. Blanchard, 2007, Journal of the American Chemical Society.