M. Tijssen

发表

Genome-wide Analysis of Simultaneous GATA1/2, RUNX1, FLI1, and SCL Binding in Megakaryocytes Identifies Hematopoietic Regulators

W. Ouwehand, B. Göttgens, N. Wilson, 2011, Developmental cell.

Deciphering transcriptional control mechanisms in hematopoiesis:the impact of high-throughput sequencing technologies.

Berthold Göttgens, Nicola K. Wilson, Marloes R. Tijssen, 2011, Experimental hematology.

A HaemAtlas: characterizing gene expression in differentiated human blood cells

S. Teichmann, W. Ouwehand, A. Attwood, 2008, Blood.

Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins.

W. Ouwehand, N. Watkins, C. Langford, 2007, Blood.

Improved postthaw viability and in vitro functionality of peripheral blood hematopoietic progenitor cells after cryopreservation with a theoretically optimized freezing curve

C. Voermans, M. Tijssen, H. Woelders, 2008, Transfusion.

Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia

William J. Astle, Warren S. Alexander, Edna C. Hardeman, 2017, The Journal of clinical investigation.

The transcription factor GATA1 regulates NBEAL2 expression through a long-distance enhancer

Marloes R. Tijssen, Chantal Thys, Kathleen Freson, 2017, Haematologica.

Serial analysis of gene expression as a tool to assess the human thyroid expression profile and to identify novel thyroidal genes.

F. Baas, C. Ris-Stalpers, M. Tijssen, 2000, The Journal of clinical endocrinology and metabolism.

Transcription Factor Levels after Forward Programming of Human Pluripotent Stem Cells with GATA1, FLI1, and TAL1 Determine Megakaryocyte versus Erythroid Cell Fate Decision

E. Turro, M. Tijssen, Jose Ballester-Beltran, 2018, Stem cell reports.

promoter in megakaryocytes near a MEIS1 binding site DNM3 A GWAS sequence variant for platelet volume marks an alternative

P. Deloukas, B. Göttgens, A. Rendon, 2013 .

A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site.

P. Deloukas, W. Ouwehand, A. Rendon, 2012, Blood.

Single site-specific integration targeting coupled with embryonic stem cell differentiation provides a high-throughput alternative to in vivo enhancer analyses

D. Dickel, B. Göttgens, A. Wilkinson, 2013, Biology Open.

Clinical approaches involving thrombopoietin to shorten the period of thrombocytopenia after high-dose chemotherapy.

C. Voermans, M. Tijssen, C. E. van der Schoot, 2006, Transfusion medicine reviews.

From stem cell to platelet

M. Tijssen, M. R. Tijssen, 2008 .

Transplantation of human peripheral blood CD34-positive cells in combination with ex vivo generated megakaryocytes results in fast platelet formation in NOD/SCID mice

C. V. D. Schoot, C. Voermans, M. Tijssen, 2008, Leukemia.

The (patho)physiology of megakaryocytopoiesis: from thrombopoietin in diagnostics and therapy to ex vivo generated cellular products

C. Voermans, M. Tijssen, C. E. van der Schoot, 2004, Vox sanguinis.

inhibitory platelet membrane proteins megakaryocytes and erythroblasts identifies novel activatory and Comparative gene expression profiling of in vitro differentiated

W. Ouwehand, C. Langford, P. Ellis, 2013 .

platelet membrane proteins inhibitory megakaryocytes and erythroblasts identifies novel activatory and Comparative gene expression profiling of in vitro differentiated

N. Watkins, C. Langford, C. V. D. Schoot, 2013 .

Canonical Wnt signaling in megakaryocytes regulates proplatelet formation.

N. Watkins, I. Macaulay, A. Rendon, 2013, Blood.

Co-expression of the collagen receptors leukocyte-associated immunoglobulin-like receptor-1 and glycoprotein VI on a subset of megakaryoblasts

P. Lenting, P. Coffer, M. Tijssen, 2010, Haematologica.

Transfer of the Full-Length Dystrophin-Coding Sequence into Muscle Cells by a Dual High-Capacity Hybrid Viral Vector with Site-Specific Integration Ability

M. Tijssen, D. Valerio, A. D. de Vries, 2005, Journal of Virology.

Chapter 5 Functional analysis of single amino-acid mutations in the Tpo-receptor c-MPL underlying congenital amegakaryocytic thrombocytopenia

C. V. D. Schoot, C. Voermans, M. Tijssen, 2008 .

Dynamin 3 participates in the growth and development of megakaryocytes.

F. D. di Summa, J. Reems, M. Tijssen, 2008, Experimental hematology.

Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specification

J. Fisher, B. Göttgens, Victoria Moignard, 2014, Development.

Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming

W. Ouwehand, M. Trotter, R. Pedersen, 2016, Nature Communications.

A novel signalling screen demonstrates that CALR mutations activate essential MAPK signalling and facilitate megakaryocyte differentiation

U. McDermott, S. Biddie, C. Gonzalez-Arias, 2016, Leukemia.

Transcriptional Regulation of Platelet Formation: Harnessing the Complexity for Efficient Platelet Production In Vitro

M. Tijssen, C. Ghevaert, T. Moreau, 2016 .

Functional analysis of single amino‐acid mutations in the thrombopoietin‐receptor Mpl underlying congenital amegakaryocytic thrombocytopenia

C. Voermans, F. D. di Summa, M. Tijssen, 2008, British journal of haematology.

Juvenile Cyclic Amegakaryocytic Thrombocytopenia: A Novel Entity

M. Tijssen, M. Bruin, M. Bierings, 2005, Journal of pediatric hematology/oncology.

Maps of Open Chromatin Guide the Functional Follow-Up of Genome-Wide Association Signals: Application to Hematological Traits

Berthold Göttgens, Nicole Soranzo, Suthesh Sivapalaratnam, 2011, PLoS genetics.

MicroRNA-486-5p is an erythroid oncomiR of the myeloid leukemias of Down syndrome.

B. Göttgens, Y. Goren, S. Michaeli, 2015, Blood.

Synergistic activation of signalling to extracellular signal-regulated kinases 1 and 2 by epidermal growth factor and 4 beta-phorbol 12-myristate 13-acetate.

J. Hornberg, J. Lankelma, M. Tijssen, 2004, European journal of biochemistry.

Transcription factors in late megakaryopoiesis and related platelet disorders

M. Tijssen, C. Ghevaert, C. Ghevaert, 2013, Journal of thrombosis and haemostasis : JTH.

provides a high-throughput alternative to in vivo enhancer analyses Single site-specific integration targeting coupled with embryonic stem cell differentiation

D. Dickel, L. Pennacchio, W. Aird, 2015 .

Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia.

C. Bloomfield, B. Göttgens, J. Schütte, 2013, Blood.

Corrigendum: Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming

W. Ouwehand, M. Trotter, R. Pedersen, 2017, Nature Communications.

Chapter 8 Thrombopoietin stimulates endothelial integrity

C. V. D. Schoot, C. Voermans, P. Hordijk, 2008 .

Genome-wide Analysis of Simultaneous GATA 1 / 2 , RUNX 1 , FLI 1 , and SCL Binding in Megakaryocytes Identifies Hematopoietic Regulators

W. Ouwehand, B. Göttgens, N. Wilson, 2011 .

Explorer A GWAS sequence variant for platelet volume marks an alternative DNM 3 promoter in megakaryocytes near a MEIS 1 binding site

P. Deloukas, W. Ouwehand, A. Rendon, 2017 .

reveal therapeutic targets in transgenic ERG myeloid leukemia Genome-scale expression and transcription factor binding profiles

C. Bloomfield, S. Kinston, R. Hannah, 2013 .

Edinburgh Research Explorer Genome-wide Analysis of Simultaneous GATA1/2, RUNX1, FLI1, and SCL Binding in Megakaryocytes Identifies Hematopoietic Regulators

Nicola K. Wilson, B. Göttgens, N. Wilson, 2022 .