P. Smethurst

发表

Genome-wide Analysis of Simultaneous GATA1/2, RUNX1, FLI1, and SCL Binding in Megakaryocytes Identifies Hematopoietic Regulators

W. Ouwehand, B. Göttgens, N. Wilson, 2011, Developmental cell.

A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders.

Sri V. V. Deevi, W. Ouwehand, A. Attwood, 2016, Blood.

Synergism between platelet collagen receptors defined using receptor-specific collagen-mimetic peptide substrata in flowing blood.

P. D. de Groot, P. Smethurst, R. Farndale, 2010, Blood.

Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood.

W. Ouwehand, P. Siljander, P. Smethurst, 2004, Blood.

Structural Basis for the Platelet-Collagen Interaction

W. Ouwehand, P. Smethurst, A. Herr, 2007, Journal of Biological Chemistry.

A comparison of platelet function in cold‐stored whole blood and platelet concentrates

R. Cardigan, M. Wiltshire, P. Smethurst, 2021, Transfusion.

The BEACH-domain containing protein, Nbeal2, interacts with Dock7, Sec16a and Vac14

William J. Astle, Luigi, P. Nurden, 2017 .

Evaluating apheresis platelets at reduced dose as a contingency measure for extreme shortages.

H. Doughty, R. Cardigan, P. Smethurst, 2021, Transfusion.

Current challenges in platelet transfusion

R. Cardigan, P. Smethurst, 2021, Platelets.

Alternatives to allogeneic platelet transfusion

P. Smethurst, L. Estcourt, S. Stanworth, 2016, British journal of haematology.

The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression.

W. Ouwehand, N. Watkins, A. Goodall, 2003, Blood.

Expression of a single‐chain human leukocyte antigen‐DRA/DRB3*01:01 molecule and differential binding of a monoclonal antibody in the presence of specifically bound human platelet antigen‐1a peptide

W. Ouwehand, P. Smethurst, S. Garner, 2014, Transfusion.

Monoclonal antibody therapies in transfusion medicine

W. Ouwehand, N. Watkins, P. Smethurst, 2004, Vox sanguinis.

A compound heterozygous mutation in glycoprotein VI in a patient with a bleeding disorder

C. Hermans, P. Smethurst, C. Van Geet, 2009, Journal of thrombosis and haemostasis : JTH.

promoter in megakaryocytes near a MEIS1 binding site DNM3 A GWAS sequence variant for platelet volume marks an alternative

P. Deloukas, B. Göttgens, A. Rendon, 2013 .

A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site.

P. Deloukas, W. Ouwehand, A. Rendon, 2012, Blood.

Gain‐ and loss‐of‐function mutants confirm the importance of apical residues to the primary interaction of human glycoprotein VI with collagen

W. Ouwehand, P. Smethurst, R. Farndale, 2006, Journal of thrombosis and haemostasis : JTH.

Rapid phenotyping of HPA‐1a using either diabody‐based hemagglutination or recombinant IgG1‐based assays

W. Ouwehand, N. Watkins, P. Smethurst, 1999, Transfusion.

Aging of platelets stored for transfusion

P. Smethurst, 2016, Platelets.

SMIM1 underlies the Vel blood group and influences red blood cell traits

Asif U. Tamuri, Gregory E. Jordan, C. A. Albers, 2013, Nature Genetics.

Integrin Activation State Determines Selectivity for Novel Recognition Sites in Fibrillar Collagens*

W. Ouwehand, P. Siljander, D. Slatter, 2004, Journal of Biological Chemistry.

Investigation of methods to detect mechanically recovered meat in meat products - IV: Immunology.

P. Smethurst, K. Hargin, K. Pickering, 1995, Meat science.

Collagen‐mimetic peptides mediate flow‐dependent thrombus formation by high‐ or low‐affinity binding of integrin α2β1 and glycoprotein VI

P. Siljander, P. Smethurst, J. Heemskerk, 2008, Journal of thrombosis and haemostasis : JTH.

Identification of a major GpVI-binding locus in human type III collagen

P. Smethurst, R. Farndale, G. Jarvis, 2008, Blood.

Identification in Collagen Type I of an Integrin α2β1-binding Site Containing an Essential GER Sequence*

P. Smethurst, R. Farndale, M. Barnes, 1998, The Journal of Biological Chemistry.

Platelet αIIbβ3 recombinant autoantibodies from the B‐cell repertoire of a post‐transfusion purpura patient

W. Ouwehand, N. Watkins, P. Smethurst, 2002 .

Selective Blockade of Glycoprotein VI Clustering on Collagen Helices*

W. Ouwehand, P. Smethurst, A. Herr, 2006, Journal of Biological Chemistry.

Calmodulin involvement in Ca2(+)-induced insulin release from electropermeabilized islets of Langerhans.

P. Bungay, P. Smethurst, M. Griffin, 1990, Biochemical Society transactions.

Measurement of tissue transglutaminase activity in a permeabilized cell system: its regulation by Ca2+ and nucleotides.

P. Smethurst, M. Griffin, Martin Griffin, 1996, The Biochemical journal.

Metabolic reprogramming under hypoxic storage preserves faster oxygen unloading from stored red blood cells

S. Sowemimo-Coker, A. Meli, R. Cardigan, 2022, Blood advances.

Stored blood has compromised oxygen unloading kinetics that can be normalized with rejuvenation and predicted from corpuscular side-scatter

A. D’Alessandro, A. Meli, R. Cardigan, 2021, Haematologica.

Rejuvenation of RBCs: validation of a manufacturing method suitable for clinical use

R. Cardigan, P. Smethurst, G. Murphy, 2019, Transfusion.

Cross-linking of cellular proteins by tissue transglutaminase during necrotic cell death: a mechanism for maintaining tissue integrity.

P. Smethurst, Richard A. Jones, M. Griffin, 2003, The Biochemical journal.

Production of calmodulin-tagged proteins in Drosophila Schneider S2 cells: a novel system for antigen production and phage antibody isolation.

W. Ouwehand, N. Watkins, J. Stephens, 2006, Journal of immunological methods.

Isolation of the V-ATPase A and c subunit cDNAs from mosquito midgut and Malpighian tubules.

L. S. Ross, S. Gill, P. Smethurst, 1998, Archives of insect biochemistry and physiology.

Inheritance of low-frequency regulatory SNPs and a rare null mutation in exon-junction complex subunit RBM8A causes TAR

Ana Cvejic, Panos Deloukas, Matthew E Hurles, 2012, Nature Genetics.

Nbeal2 interacts with Dock7, Sec16a, and Vac14.

William J. Astle, W. Ouwehand, P. Nurden, 2018, Blood.

Assessment of the soluble proteins HMGB1, CD40L and CD62P during various platelet preparation processes and the storage of platelet concentrates: The BEST collaborative study

P. Tiberghien, R. Cardigan, P. Smethurst, 2022, Transfusion.

Exome sequencing identifies NBEAL2 as the causative gene for Gray Platelet Syndrome

Gregory E. Jordan, C. A. Albers, W. Ouwehand, 2011, Nature Genetics.

Threonine-145/Methionine-145 variants of baculovirus produced recombinant ligand binding domain of GPIbα express HPA-2 epitopes and show equal binding of von Willebrand factor

Peter A. Smethurst, Willem H. Ouwehand, W. Ouwehand, 2000 .

Threonine-145/methionine-145 variants of baculovirus produced recombinant ligand binding domain of GPIbalpha express HPA-2 epitopes and show equal binding of von Willebrand factor.

W. Ouwehand, P. Smethurst, S. Garner, 2000, Blood.

The effect of recombinant IgG antibodies against the leucine-33 form of the platelet β3 integrin (HPA-1a) on platelet function

W. Ouwehand, N. Watkins, P. D. de Groot, 2004, Thrombosis and Haemostasis.

Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody.

Richard W Farndale, Ashley Buckle, W. Ouwehand, 2004, Blood.

Inhibition of MT1-MMP activity using functional antibody fragments selected against its hemopexin domain.

W. Ouwehand, N. Watkins, W. English, 2012, The international journal of biochemistry & cell biology.

A comprehensive high-throughput sequencing test for the diagnosis of inherited bleeding , thrombotic and platelet disorders

Sri V. V. Deevi, W. Ouwehand, J. Jolley, 2015 .

A 2-step mechanism of arterial thrombus formation induced by human atherosclerotic plaques.

I. Bernlochner, P. Smethurst, C. Gachet, 2010, Journal of the American College of Cardiology.

Physical and Functional Interaction Between Cell-Surface Calreticulin and the Collagen Receptors Integrin α2β1 and Glycoprotein VI in Human Platelets

P. Smethurst, P. Eggleton, Catherine M. Elton, 2002, Thrombosis and Haemostasis.

Definition of novel GP6 polymorphisms and major difference in haplotype frequencies between populations by a combination of in‐depth exon resequencing and genotyping with tag single nucleotide polymorphisms

W. Ouwehand, N. Watkins, F. Dudbridge, 2006, Journal of thrombosis and haemostasis : JTH.

THROMBOSIS AND HEMOSTASIS A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders