M. Kupryushkin

发表

Study of the Staudinger Reaction and Reveal of Key Factors Affecting the Efficacy of Automatic Synthesis of Phosphoryl Guanidinic Oligonucleotide Analogs

D. Pyshnyi, M. A. Bazhenov, A. Shernyukov, 2019, Russian Journal of Bioorganic Chemistry.

Pronounced therapeutic potential of oligonucleotides fixed on inorganic nanoparticles against highly pathogenic H5N1 influenza A virus in vivo.

D. Pyshnyi, M. Kupryushkin, Z. Ismagilov, 2021, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Amphiphilic “Like-A-Brush” Oligonucleotide Conjugates with Three Dodecyl Chains: Self-Assembly Features of Novel Scaffold Compounds for Nucleic Acids Delivery

D. Pyshnyi, M. Kupryushkin, I. Pyshnaya, 2020, Nanomaterials.

Novel Peptide Conjugates of Modified Oligonucleotides for Inhibition of Bacterial RNase P

A. Davydova, D. Pyshnyi, S. Altman, 2019, Front. Pharmacol..

Antisense oligonucleotide gapmers containing phosphoryl guanidine groups reverse MDR1-mediated multiple drug resistance of tumor cells

I. V. Chernikov, D. Pyshnyi, S. Altman, 2021, Molecular therapy. Nucleic acids.

Phosphoryl Guanidines: A New Type of Nucleic Acid Analogues

D. Pyshnyi, M. Kupryushkin, D. Stetsenko, 2014, Acta naturae.

A Comparative Study of the Hybridization of Phosphoryl Guanidine Oligonucleotides with DNA and RNA

D. Pyshnyi, M. Kupryushkin, A. Lomzov, 2021, Russian Journal of Bioorganic Chemistry.

In vivo hypotensive effect of aminosilanol-based nanocomposites bearing antisense oligonucleotides

M. Kupryushkin, A. Levina, M. Repkova, 2022, Journal of Drug Delivery Science and Technology.

Pre-steady state kinetics of DNA binding and abasic site hydrolysis by tyrosyl-DNA phosphodiesterase 1

D. Pyshnyi, M. Kupryushkin, D. Stetsenko, 2017, Journal of biomolecular structure & dynamics.

Synthesis of Novel Representatives of Phosphoryl Guanidine Oligonucleotides

S. A. Zhukov, M. Kupryushkin, D. Pyshnyi, 2021, Russian Journal of Bioorganic Chemistry.

A convenient solid phase approach to obtain lipophilic 5′-phosphoramidate derivatives of DNA and RNA oligonucleotides

D. Pyshnyi, M. Kupryushkin, E. Apartsin, 2018, Nucleosides, nucleotides & nucleic acids.

Design of a New Fluorescent Oligonucleotide-Based Assay for a Highly Specific Real-Time Detection of Apurinic/Apyrimidinic Site Cleavage by Tyrosyl-DNA Phosphodiesterase 1.

D. Pyshnyi, M. Kupryushkin, D. Stetsenko, 2015, Bioconjugate chemistry.

Prevention of DNA multimerization using phosphoryl guanidine primers during isothermal amplification with Bst exo- DNA polymerase.

A. R. Sakhabutdinova, D. Pyshnyi, M. Kupryushkin, 2019, Biochimie.

Efficient functionalization of oligonucleotides by new achiral nonnucleosidic monomers.

D. Pyshnyi, M. Kupryushkin, D. Stetsenko, 2014, Organic letters.

The Lipophilic Purine Nucleoside—Tdp1 Inhibitor—Enhances DNA Damage Induced by Topotecan In Vitro and Potentiates the Antitumor Effect of Topotecan In Vivo

M. Kupryushkin, O. Lavrik, E. Ilina, 2022, Molecules.

Oligonucleotide derivatives in nucleic acid hybridization analysis. III. Synthesis and investigation of properties of oligonucleotides, bearing bifunctional non-nucleotide insertion

D. Pyshnyi, M. Kupryushkin, 2012, Russian Journal of Bioorganic Chemistry.

Oligonucleotide Functionalization by a Novel Alkyne-Modified Nonnucleosidic Reagent Obtained by Versatile Building Block Chemistry

D. Pyshnyi, M. Kupryushkin, D. Stetsenko, 2013, Nucleosides, nucleotides & nucleic acids.

Transport Oligonucleotides—A Novel System for Intracellular Delivery of Antisense Therapeutics

I. V. Chernikov, D. Pyshnyi, V. Vlassov, 2020, Molecules.

Antiviral Activity of a New Class of Chemically Modified Antisense Oligonucleotides against Influenza А Virus

D. Pyshnyi, M. Kupryushkin, M. Zenkova, 2019, Russian Journal of Bioorganic Chemistry.

Physicochemical Properties of the Phosphoryl Guanidine Oligodeoxyribonucleotide Analogs

D. Pyshnyi, M. Kupryushkin, A. Lomzov, 2019, Russian Journal of Bioorganic Chemistry.

Diastereomers of a mono-substituted phosphoryl guanidine trideoxyribonucleotide: Isolation and properties.

D. Pyshnyi, A. Shernyukov, M. Kupryushkin, 2019, Biochemical and biophysical research communications.

Surface modification of SOI-FET sensors for label-free and specific detection of short RNA analyte.

D. Pyshnyi, M. Kupryushkin, E. Dmitrienko, 2016, Nanomedicine.

A convenient method for the synthesis of phosphoramidite non-nucleotide inserts for preparation of functionalized oligonucleotides

M. Kupryushkin, D. Pyshnyi, 2012, Russian Journal of Bioorganic Chemistry.

A Versatile Approach to Attachment of Triarylmethyl Labels to DNA for Nanoscale Structural EPR Studies at Physiological Temperatures.

D. Pyshnyi, M. Fedin, M. Kupryushkin, 2018, The journal of physical chemistry. B.

Oxidative damage to epigenetically methylated sites affects DNA stability, dynamics and enzymatic demethylation

D. R. Gruber, A. Shernyukov, M. Kupryushkin, 2018, Nucleic acids research.

New oligonucleotide derivatives as unreactive substrate analogues and potential inhibitors of human apurinic/apyrimidinic endonuclease APE1.

D. Pyshnyi, M. Kupryushkin, D. Stetsenko, 2016, Molecular bioSystems.

Triazinylamidophosphate Oligonucleotides: Synthesis and Study of Their Interaction with Cells and DNA-Binding Proteins

M. Kupryushkin, S. Khodyreva, O. Lavrik, 2021, Russian Journal of Bioorganic Chemistry.

Validation of Heterophase RNA Analysis with the Use of a Silicon-on-Insulator Biosensor

M. Kupryushkin, E. Dmitrienko, I. Pyshnaya, 2021 .

SDS‐PAGE procedure: Application for characterization of new entirely uncharged nucleic acids analogs

D. Pyshnyi, M. Kupryushkin, I. Pyshnaya, 2018, Electrophoresis.

An Influence of Modification with Phosphoryl Guanidine Combined with a 2′-O-Methyl or 2′-Fluoro Group on the Small-Interfering-RNA Effect

D. Pyshnyi, M. Kupryushkin, I. Pyshnaya, 2021, International journal of molecular sciences.

Validation of Heterophase RNA Analysis with the Use of a Silicon-on-Insulator Biosensor

M. Kupryushkin, E. Dmitrienko, I. Pyshnaya, 2021, Optoelectronics, Instrumentation and Data Processing.

Algorithm for Searching and Testing the Activity of Antisense Oligonucleotides Exemplified by the mRNA of the rpoD Gene Encoding Staphylococcus aureus RNA Polymerase Sigma Factor

D. Pyshnyi, M. Kupryushkin, M. Zenkova, 2019, Russian journal of bioorganic chemistry.

Problems of the Synthesis of Oligonucleotide Derivatives in the Realization of the Anchimeric Effect

D. Pyshnyi, M. Kupryushkin, I. Pyshnaya, 2021 .

Complexes and Supramolecular Associates of Dodecyl-Containing Oligonucleotides with Serum Albumin

D. Pyshnyi, M. Kupryushkin, I. Pyshnaya, 2023, Biochemistry (Moscow).

Fork- and Comb-like Lipophilic Structures: Different Chemical Approaches to the Synthesis of Oligonucleotides with Multiple Dodecyl Residues

M. Kupryushkin, S. Khodyreva, O.V. Markov, 2023, International journal of molecular sciences.