J. Starkopf

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Oxidative stress and ischaemia-reperfusion of the heart : a clinical and experimental study

J. Starkopf, 1997 .

ESICM LIVES 2016: part one

Hester F. Lingsma, A. M. Cavalheiro, H. S. King, 2016, Intensive Care Medicine Experimental.

Translating the European Society for Clinical Nutrition and Metabolism 2019 guidelines into practice.

J. Starkopf, A. Deane, A. Reintam Blaser, 2019, Current opinion in critical care.

GlucoseControl system for blood glucose control in intensive care patients a European multicentre observational study

U. Jaschinski, J. Starkopf, J. Chvojka, 2016 .

Space GlucoseControl system for blood glucose control in intensive care patients - a European multicentre observational study

U. Jaschinski, J. Starkopf, J. Chvojka, 2015, BMC Anesthesiology.

Population pharmacokinetics and pharmacodynamics of dobutamine in neonates on the first days of life

H. Soeorg, J. Starkopf, T. Metsvaht, 2020, British journal of clinical pharmacology.

Population Pharmacokinetics and Dosing of Milrinone After Patent Ductus Arteriosus Ligation in Preterm Infants.

J. Starkopf, T. Metsvaht, J. Standing, 2019, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

Adaptation to Ischemia by in vivo Exposure to Hyperoxia—Signalling through Mitogen Activated Protein Kinases and Nuclear Factor Kappa B

J. Starkopf, G. Valen, J. Vaage, 2003 .

Cardioprotection by breathing hyperoxic gas-relation to oxygen concentration and exposure time in rats and mice.

J. Starkopf, G. Valen, J. Vaage, 2002, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Preconditioning with hydrogen peroxide (H2O2) or ischemia in H2O2-induced cardiac dysfunction.

J. Starkopf, G. Valen, J. Vaage, 1998, Free radical research.

Lipid peroxidation, arachidonic acid and products of the lipoxygenase pathway in ischaemic preconditioning of rat heart.

J. Starkopf, K. Ytrehus, T. Andreasen, 1998, Cardiovascular research.

The Effect of Remote Ischaemic Preconditioning on Arterial Stiffness in Patients Undergoing Vascular Surgery: A Randomised Clinical Trial.

J. Starkopf, J. Kals, M. Zilmer, 2019, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

Prevalence of malnutrition in various political, economic, and geographic settings.

K. Poulia, J. Starkopf, P. Paluszkiewicz, 2015, JPEN. Journal of parenteral and enteral nutrition.

Exposure of rats to hyperoxia enhances relaxation of isolated aortic rings and reduces infarct size of isolated hearts.

J. Starkopf, J. Kals, G. Valen, 2002, Acta physiologica Scandinavica.

Hypophosphatemia in critically ill adults and children - A systematic review.

M. Berger, M. Malbrain, J. Wernerman, 2020, Clinical nutrition.

The role of elevated high-sensitivity cardiac troponin on outcomes following severe blunt chest trauma.

J. Starkopf, P. Talving, S. Saar, 2019, Injury.

Moderate intra-abdominal hypertension is associated with an increased lactate-pyruvate ratio in the rectus abdominis muscle tissue: a pilot study during laparoscopic surgery

J. Tenhunen, J. Starkopf, L. Maddison, 2012, Annals of Intensive Care.

Moderate Intra-Abdominal Hypertension Leads to Anaerobic Metabolism in the Rectus Abdominis Muscle Tissue of Critically Ill Patients: A Prospective Observational Study

J. Tenhunen, J. Starkopf, Ü. Kirsimägi, 2014, BioMed research international.

Remote Ischaemic Preconditioning Reduces Kidney Injury Biomarkers in Patients Undergoing Open Surgical Lower Limb Revascularisation: A Randomised Trial

J. Starkopf, J. Kals, M. Zilmer, 2020, Oxidative medicine and cellular longevity.

Remote Ischaemic Preconditioning Attenuates Cardiac Biomarkers During Vascular Surgery: A Randomised Clinical Trial.

J. Starkopf, J. Kals, M. Zilmer, 2019, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

Antioxidant UPF1 attenuates myocardial stunning in isolated rat hearts.

M. Kals, J. Starkopf, J. Kals, 2008, International journal of cardiology.

Letter to the Editor Antioxidant UPF1 attenuates myocardial stunning in isolated rat hearts

M. Kals, J. Starkopf, J. Kals, 2008 .

Antioxidant UPF 1 attenuates myocardial stunning in isolated rat hearts ☆

M. Kals, J. Starkopf, J. Kals, 2007 .

Genetic variants in humanin nuclear isoform gene regions show no association with coronary artery disease

R. Mägi, S. Kõks, J. Starkopf, 2019, BMC Research Notes.

Hyperoxia elicits myocardial protection through a nuclear factor kappaB-dependent mechanism in the rat heart.

J. Starkopf, G. Valen, J. Vaage, 2003, The Journal of thoracic and cardiovascular surgery.

The evidence of oxidative stress in cardiac surgery and septic patients: a comparative study.

J. Starkopf, M. Zilmer, K. Tamme, 1997, Clinica chimica acta; international journal of clinical chemistry.

Time course of oxidative stress during open-heart surgery.

J. Starkopf, T. Kullisaar, T. Vihalemm, 1995, Scandinavian journal of thoracic and cardiovascular surgery.

Off-Pump Coronary Surgery causes Immediate Release of Myocardial Damage Markers

J. Starkopf, I. Karu, M. Zilmer, 2009, Asian cardiovascular & thoracic annals.

Preischemic bradykinin and ischaemic preconditioning in functional recovery of the globally ischaemic rat heart.

J. Starkopf, K. Ytrehus, E. Bugge, 1997, Cardiovascular research.

Growth Factors Serum Levels in Coronary Artery Disease Patients Scheduled for Bypass Surgery: Perioperative Dynamics and Comparisons with Healthy Volunteers

J. Starkopf, I. Karu, K. Zilmer, 2013, BioMed research international.

A first update on mapping the human genetic architecture of COVID-19

Eurie L. Hong, E. F. Perez, Rachel G Liao, 2022, Nature.

In vivo chronic carvedilol treatment in rats attenuates ex vivo regional infarction of the heart

J. Starkopf, K. Ytrehus, O. Mjøs, 2006, Scandinavian cardiovascular journal : SCJ.

Remote ischaemic preconditioning influences the levels of acylcarnitines in vascular surgery: a randomised clinical trial

J. Starkopf, J. Kals, M. Zilmer, 2020, Nutrition & Metabolism.

Developing the University of Tartu in Estonia into a well-networked Patient Safety Research Centre (PATSAFE): A study protocol

K. Põlluste, M. Lember, J. Starkopf, 2022, Open Research Europe.

Effects of 60 minutes of hyperoxia followed by normoxia before coronary artery bypass grafting on the inflammatory response profile and myocardial injury

J. Starkopf, I. Karu, A. Ruusalepp, 2012, Journal of Negative Results in BioMedicine.

Pre‐treatment with hyperoxia before coronary artery bypass grafting – effects on myocardial injury and inflammatory response

J. Starkopf, I. Karu, K. Zilmer, 2007, Acta anaesthesiologica Scandinavica.

Associations between elevated high-sensitive cardiac troponin t and outcomes in patients with acute abdominal pain

T. Marandi, J. Starkopf, P. Talving, 2022, European Journal of Trauma and Emergency Surgery.

Incidence, Risk Factors, and Outcomes of Intra-Abdominal Hypertension in Critically Ill Patients—A Prospective Multicenter Study (IROI Study)

J. Starkopf, P. Greiffenstein, W. Davis, 2019, Critical care medicine.

Mild to moderate intra-abdominal hypertension: Does it matter?

J. Starkopf, A. Reintam Blaser, L. Maddison, 2016, World journal of critical care medicine.

Should we measure intra-abdominal pressures in every intensive care patient?

J. Starkopf, A. Blaser, K. Tamme, 2012, Annals of Intensive Care.

Monitoring and parenteral administration of micronutrients, phosphate and magnesium in critically ill patients: The VITA-TRACE survey.

M. Berger, P. Singer, S. Jakob, 2020, Clinical nutrition.

Epidemiology and outcome of out-of-hospital resuscitation from cardiac arrest of non-cardiac origin

J. Starkopf, V. Reinhard, A. Sipria, 2008 .

Two cases of takotsubo syndrome related to tracheal intubation/extubation.

J. Starkopf, T. Jakobson, K. Tamme, 2012, Medicina.

An antioxidant tetrapeptide UPF1 in rats has a neuroprotective effect in transient global brain ischemia

J. Starkopf, J. Kals, Ü. Langel, 2004, Neuroscience Letters.

Inflammatory/oxidative stress during the first week after different types of cardiac surgery

J. Starkopf, I. Karu, K. Zilmer, 2010, Scandinavian cardiovascular journal : SCJ.

The black box revelation: monitoring gastrointestinal function.

M. Malbrain, J. Starkopf, H. O. Oudemans-van Straaten, 2014, Anaesthesiology intensive therapy.

Prevalence of hypophosphatemia in the ICU - Results of an international one-day point prevalence survey.

M. Berger, S. Schaller, J. Starkopf, 2020, Clinical nutrition.

Incidence and outcomes of acute mesenteric ischaemia: a systematic review and meta-analysis

S. Acosta, J. Starkopf, J. Kals, 2022, BMJ Open.

Pretreating rats with hyperoxia attenuates ischemia-reperfusion injury of the heart.

J. Starkopf, G. Valen, J. Vaage, 2001, Life sciences.

Replacing Protein via Enteral Nutrition in a Stepwise Approach in Critically Ill Patients: A Multicenter Randomized Controlled Trial: The REPLENISH Trial Protocol

J. Preiser, J. Starkopf, A. Perner, 2022, medRxiv.

Early postoperative function of the heart after coronary artery bypass grafting is not predicted by myocardial necrosis and glutathione-associated oxidative stress.

J. Starkopf, I. Karu, C. Kairane, 2005, Clinica chimica acta; international journal of clinical chemistry.

Pretreatment with methylprednisolone protects the isolated rat heart against ischaemic and oxidative damage

J. Starkopf, G. Valen, J. Vaage, 2000, Free radical research.

A sensitive method for the simultaneous UHPLC-MS/MS analysis of milrinone and dobutamine in blood plasma using NH4F as the eluent additive and ascorbic acid as a stabilizer.

J. Starkopf, T. Metsvaht, Rūta Veigure, 2019, Clinical mass spectrometry.

Abdominal Compartment Syndrome: Improving Outcomes With A Multidisciplinary Approach – A Narrative Review

J. Starkopf, P. Talving, M. Padar, 2019, Journal of multidisciplinary healthcare.

A Systematic Review And Individual Patient Data Meta-Analysis On Intraabdominal Hypertension In Critically Ill Patients: The Wake-Up Project World Initiative on Abdominal Hypertension Epidemiology, a Unifying Project (WAKE-Up!).

P. Pelosi, A. Kirkpatrick, M. Malbrain, 2013, Minerva anestesiologica.

Correction: Gastrointestinal Failure score in critically ill patients: a prospective observational study

J. Starkopf, A. Reintam, H. Kern, 2008, Critical Care.

Effects of High Volume Haemodiafiltration on Inflammatory Response Profile and Microcirculation in Patients with Septic Shock

J. Starkopf, H. Kern, K. Tamme, 2015, BioMed research international.

Dosing of Milrinone in Preterm Neonates to Prevent Postligation Cardiac Syndrome: Simulation Study Suggests Need for Bolus Infusion

J. Starkopf, T. Metsvaht, M. Hallik, 2016, Neonatology.

Gastrointestinal function in intensive care patients: terminology, definitions and management. Recommendations of the ESICM Working Group on Abdominal Problems

S. Jakob, M. Malbrain, C. Spies, 2012, Intensive Care Medicine.

Gastrointestinal Failure score in critically ill patients: a prospective observational study

J. Starkopf, A. Reintam, H. Kern, 2008, Critical care.

Abdominal signs and symptoms in intensive care patients.

M. Malbrain, J. Starkopf, A. Reintam Blaser, 2015, Anaesthesiology intensive therapy.

Successful liver transplantation after 21 days of hepatic coma.

J. Starkopf, T. Väli, M. Hallik, 2011, ASAIO journal.

Mapping the human genetic architecture of COVID-19

Mattia G. Bergomi, Christopher M. DeBoever, Matthew A. Wiles, 2021, Nature.

Gastrointestinal symptoms in intensive care patients

J. Starkopf, A. Reintam, A Reintam, 2009, Acta anaesthesiologica Scandinavica.

Perioperative penetration of metronidazole into muscle tissue: a microdialysis study

J. Starkopf, R. Pähkla, J. Karjagin, 2004, European Journal of Clinical Pharmacology.

Comparison of different definitions of feeding intolerance: A retrospective observational study.

J. Starkopf, A. Deane, M. Poeze, 2015, Clinical nutrition.

Early enteral nutrition in critically ill patients: ESICM clinical practice guidelines

M. Berger, P. Singer, S. Jakob, 2017, Intensive Care Medicine.

Perioperative gastrointestinal problems in the ICU.

M. Malbrain, J. Starkopf, H. O. Oudemans-van Straaten, 2014, Anaesthesiology intensive therapy.

Expanded Measurements of Intra-Abdominal Pressure Do Not Increase the Detection Rate of Intra-Abdominal Hypertension: A Single-Center Observational Study*

J. Starkopf, A. Blaser, K. Tamme, 2014, Critical care medicine.

Pretreatment by hyperoxia--a tool to reduce ischaemia-reperfusion injury in the myocardium.

J. Starkopf, I. Karu, A. Ruusalepp, 2010, Current clinical pharmacology.

Definition, prevalence, and outcome of feeding intolerance in intensive care: a systematic review and meta‐analysis

J. Starkopf, A. Deane, A. Blaser, 2014, Acta anaesthesiologica Scandinavica.

The reasons for insufficient enteral feeding in an intensive care unit: A prospective observational study.

J. Starkopf, A. Reintam Blaser, Maarja Kuslapuu, 2015, Intensive & critical care nursing.

DEFINING GASTROINTESTINAL FAILURE

J. Starkopf, A. Reintam, H. Kern, 2007, Acta clinica Belgica.

Postoperative complications and mortality after major gastrointestinal surgery.

J. Starkopf, M. Padar, L. Starkopf, 2014, Medicina.

Risk factors for intra-abdominal hypertension and abdominal compartment syndrome among adult intensive care unit patients: a systematic review and meta-analysis

Chad G Ball, Andrew W Kirkpatrick, Henry Thomas Stelfox, 2013, Critical Care.

Pharmacokinetics and pharmacodynamics of piperacillin/tazobactam during high volume haemodiafiltration in patients with septic shock

J. Starkopf, K. Oselin, T. Metsvaht, 2016, Acta anaesthesiologica Scandinavica.

Clinical evaluation of the intestinal microcirculation using sidestream dark field imaging--recommendations of a round table meeting.

J. Starkopf, V. Černý, C. Lehmann, 2014, Clinical hemorheology and microcirculation.

Intra-abdominal hypertension and hypoxic respiratory failure together predict adverse outcome - A sub-analysis of a prospective cohort.

M. Malbrain, P. V. van Heerden, J. Starkopf, 2021, Journal of critical care.

Protective effect of antioxidants on pulmonary endothelial function after cardiopulmonary bypass.

Mihkel Zilmer, J. Starkopf, J. Vaage, 2003, Journal of cardiothoracic and vascular anesthesia.

Pharmacokinetics of doripenem during high volume hemodiafiltration in patients with septic shock

J. Starkopf, K. Oselin, T. Metsvaht, 2015, Journal of clinical pharmacology.

Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study

Mohd Shahnaz Hasan, H. Hashimoto, S. Vansteelandt, 2020, Intensive Care Medicine.

Enteral nutrition and dynamics of citrulline and intestinal fatty acid-binding protein in adult ICU patients.

A. Forbes, S. Jakob, J. Wernerman, 2021, Clinical nutrition ESPEN.

Gastrointestinal failure in the ICU

S. Jakob, J. Starkopf, A. Reintam Blaser, 2016, Current opinion in critical care.

Gastrointestinal symptoms during the first week of intensive care are associated with poor outcome: a prospective multicentre study

M. Björck, M. Malbrain, J. Starkopf, 2013, Intensive Care Medicine.

Gastrointestinal failure in intensive care: a retrospective clinical study in three different intensive care units in Germany and Estonia

C. Spies, L. Tooding, J. Starkopf, 2006, BMC gastroenterology.

Development of the Gastrointestinal Dysfunction Score (GIDS) for critically ill patients - A prospective multicenter observational study (iSOFA study).

K. Fischer, G. Elke, S. Jakob, 2021, Clinical nutrition.

Pharmacokinetics of Meropenem Determined by Microdialysis in the Peritoneal Fluid of Patients With Severe Peritonitis Associated With Septic Shock

W. Couet, J. Starkopf, K. Oselin, 2008, Clinical pharmacology and therapeutics.

Aortic arch thrombosis in a neonate with heterozygous carrier status of factor V Leiden mutation.

J. Starkopf, T. Metsvaht, H. Kern, 2006, Congenital heart disease.

Intra-Abdominal Hypertension and Gastrointestinal Symptoms in Mechanically Ventilated Patients

J. Starkopf, A. Reintam Blaser, P. Parm, 2011, Critical care research and practice.

Risk factors for intra‐abdominal hypertension in mechanically ventilated patients

J. Starkopf, A. Blaser, R. Kitus, 2011, Acta anaesthesiologica Scandinavica.

Intra-abdominal or retroperitoneal tumors Prone positioning Massive incisional hernia repair Acute pancreatitis Distended abdomen Damage control laparatomy Laparoscopy with excessive inflation pressures Peritoneal dialysis

J. Starkopf, A. Blaser, R. Kitus, 2011 .

Cardiovascular SOFA score may not reflect current practice

Kaspar F. Bachmann, Y. Arabi, J. Starkopf, 2021, Intensive Care Medicine.

Intra-abdominal hypertension and abdominal compartment syndrome in the critically ill liver cirrhotic patient–prevalence and clinical outcomes. A multicentric retrospective cohort study in intensive care

J. Starkopf, F. Saliba, S. Blot, 2021, PloS one.

Primary and secondary intra-abdominal hypertension—different impact on ICU outcome

J. Starkopf, A. Reintam, H. Kern, 2008, Intensive Care Medicine.

Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine

M. Berger, P. Singer, G. Elke, 2020, Critical Care.

WHO SHOULD BE CONSIDERED FOR NUTRITIONAL THERAPY IN ICU?

J. Starkopf, A. Deane, A. Reintam Blaser, 2019 .

Implementation of enteral feeding protocol in an intensive care unit: Before-and-after study

J. Starkopf, M. Padar, G. Uusvel, 2017, World journal of critical care medicine.

Long-term outcome of bystander-witnessed out-of-hospital cardiac arrest in Estonia from 1999 to 2002.

J. Starkopf, K. Lang, H. Pisarev, 2009, Resuscitation.

Exposure to sixty minutes of hyperoxia upregulates myocardial humanins in patients with coronary artery disease - a pilot study.

S. Kõks, J. Starkopf, I. Karu, 2015, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

I. KARU1,2, P. TAHEPOLD2,3, A. RUUSALEPP3, E. REIMANN4, S. KOKS4, J. STARKOPF2 EXPOSURE TO SIXTY MINUTES OF HYPEROXIAUPREGULATES MYOCARDIAL HUMANINS IN PATIENTS WITH CORONARY ARTERY DISEASE-A PILOT STUDY

S. Kõks, J. Starkopf, A. Ruusalepp, 2016 .

Gastrointestinal failure affects outcome of intensive care.

J. Starkopf, M. Padar, G. Uusvel, 2019, Journal of critical care.

A systematic review and individual patient data meta-analysis on intra-abdominal hypertension in critically ill patients: the wake-up project. World initiative on Abdominal Hypertension Epidemiology, a Unifying Project (WAKE-Up!).

P. Pelosi, A. Kirkpatrick, M. Malbrain, 2014, Minerva anestesiologica.

The clinical relevance of oliguria in the critically ill patient: analysis of a large observational database

Bee Hong Tan, D. J. Hawkins, Fernando M. Maroto, 2020, Critical care.

Changes of plasma asymmetric dimethylarginine levels after coronary artery bypass grafting

J. Starkopf, I. Karu, K. Zilmer, 2006, Scandinavian Cardiovascular Journal.

Replacing protein via enteral nutrition in a stepwise approach in critically ill patients: the REPLENISH randomized clinical trial protocol

Mohammed S. Alhumaid, J. Preiser, G. Rasool, 2023, Trials.

Severe Trauma in Estonia: 256 consecutive cases analysed and the impact on outcomes comparing two regions

J. Starkopf, T. Asser, T. Metsvaht, 2016, European Journal of Trauma and Emergency Surgery.

J. Starkopf, F. Saliba, S. Blot, 2021 .

Acute abdominal pain at referral emergency departments: an analysis of performance of three time-dependent quality indicators

J. Starkopf, P. Talving, Ü. Kirsimägi, 2023, European Journal of Trauma and Emergency Surgery.

Mapping the human genetic architecture of COVID-19

Mattia G. Bergomi, Christopher M. DeBoever, Matthew A. Wiles, 2021, Nature.

Mapping the human genetic architecture of COVID-19

Eurie L. Hong, E. F. Perez, Rachel G Liao, 2021 .

Sublingual microcirculation in patients with intra-abdominal hypertension: a pilot study in 15 critically ill patients.

J. Starkopf, L. Maddison, J. Karjagin, 2014, Journal of critical care.

Current practice and variability in micronutrient monitoring and administration: results of the Vita-Trace survey

M. Berger, P. Singer, S. Jakob, 2019 .

The updated clinical guideline development process in Estonia is an efficient method for developing evidence-based guidelines.

S. Hill, L. Bero, J. Starkopf, 2013, Journal of clinical epidemiology.

Gastrointestinal failure in the ICU

S. Jakob, J. Starkopf, A. Reintam Blaser, 2016, Current opinion in critical care.

Variation in Severity-Adjusted Resource use and Outcome for Neurosurgical Emergencies in the Intensive Care Unit

J. Takala, S. Jakob, J. Starkopf, 2023, Neurocritical care.

Diagnostic accuracy of biomarkers to detect acute mesenteric ischaemia in adult patients: a systematic review and meta-analysis

M. Björck, J. Starkopf, A. Reintam Blaser, 2023, World Journal of Emergency Surgery.

Identifying patient safety research priorities in Estonia: results of a Delphi consensus study

M. Lember, J. Starkopf, M. Kangasniemi, 2022, BMJ Open Quality.

Sublingual microcirculatory changes during transient intra-abdominal hypertension--a prospective observational study in laparoscopic surgery patients.

J. Starkopf, L. Maddison, Juri Karjagin, 2014, Clinical hemorheology and microcirculation.