J. Gerdes

发表

Positron emission tomography studies of organophosphate chemical threats and oxime countermeasures

H. VanBrocklin, C. Thompson, J. Gerdes, 2019, Neurobiology of Disease.

Inhibitor of the glutamate vesicular transporter (VGLUT).

R. Bridges, C. Thompson, J. Gerdes, 2005, Current medicinal chemistry.

The substituted aspartate analogue l-β-threo-benzyl-aspartate preferentially inhibits the neuronal excitatory amino acid transporter EAAT3

M. Kavanaugh, P. A. Wilson, D. Poulsen, 2005, Neuropharmacology.

Lavendamycin antitumor agents: structure-based design, synthesis, and NAD(P)H:quinone oxidoreductase 1 (NQO1) model validation with molecular docking and biological studies.

J. Gerdes, W. Holloway, D. Holley, 2008, Journal of medicinal chemistry.

Isoxazole analogues bind the system xc- transporter: structure-activity relationship and pharmacophore model.

R. Bridges, B. Twamley, J. Gerdes, 2010, Bioorganic & medicinal chemistry.

Synthesis and anti-acetylcholinesterase properties of novel β- and γ-substituted alkoxy organophosphonates.

C. Thompson, J. Gerdes, Chih-Kai Chao, 2013, Bioorganic & medicinal chemistry letters.

A simple methodology for the production of three-dimensional models: serotonin transporter as an example

P. A. Wilson, J. Gerdes, 2004 .

The development of benzo- and naphtho-fused quinoline-2,4-dicarboxylic acids as vesicular glutamate transporter (VGLUT) inhibitors reveals a possible role for neuroactive steroids.

Erin S. Bolstad, R. Bridges, C. Thompson, 2014, Bioorganic & medicinal chemistry letters.

Inhibition of the Vesicular Glutamate Transporter (VGLUT) with Congo Red Analogs: New Binding Insights.

R. Bridges, C. Thompson, J. Gerdes, 2021, Neurochemical research.

5HT1a Receptor Binding Affinities of a Series of Serotonin Transporter (SERT) Inhibitors and Related Thermodynamic Insights

Michael R. Braden, E. Novellino, J. Gerdes, 2015 .

Radiosynthesis, ex Vivo Biodistribution, and in Vivo Positron Emission Tomography Imaging Evaluations of [11C]2-Pyridinealdoxime Methiodide ([11C]2-PAM): A First-In-Class Antidote Tracer for Organophosphate Intoxication.

H. VanBrocklin, C. Thompson, J. Gerdes, 2018, ACS chemical neuroscience.

Biochemical properties of A-homovitamin D derivatives: 1,4-dihydroxy-3-deoxy-A-homo-19-nor-9, 10-secocholesta-5,7-dienes.

A. Norman, J. Gerdes, W. Okamura, 1981, Archives of biochemistry and biophysics.

Development of effective PET and SPECT imaging agents for the serotonin transporter: has a twenty-year journey reached its destination?

Yiyun Huang, J. Gerdes, M. Zheng, 2010, Current topics in medicinal chemistry.

Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O‐(2‐[18F]fluoroethyl)‐O‐(p‐nitrophenyl)methylphosphonate [18F]‐VXS

P. Taylor, C. Thompson, J. Gerdes, 2020, Annals of the New York Academy of Sciences.

Synthesis and in vitro evaluation of 2,3-dimethoxy-5-(fluoroalkyl)-substituted benzamides: high-affinity ligands for CNS dopamine D2 receptors.

R. Mailman, C. Mathis, J. Gerdes, 1991, Journal of medicinal chemistry.

Binding Potency of Paroxetine Analogues for the 5‐Hydroxytryptamine Uptake Complex *

C. Mathis, J. Gerdes, S. Peroutka, 1992, The Journal of pharmacy and pharmacology.

High pressure nucleophilic fluoride-ion substitution reactions: formation of fluoroalkylbenzenes

C. Mathis, J. Gerdes, A. Shulgin, 1996 .

Synthesis of 1-[2',5'-dimethoxy-4'-(β-fluoroethyl)phenyl]-2-aminopropane: studies related to 18F-labeled serotonin receptor ligands

C. Mathis, J. Gerdes, A. Shulgin, 1988 .

Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors.

Nichole A. Tower, M. Heise, B. Tekwani, 2021, Journal of medicinal chemistry.

Organic reactions at high pressure. Conversion of cyclic alkanones and enones to 1,3-dioxolanes

W. G. Dauben, J. Gerdes, G. Look, 1986 .

Organic reactions at high pressure. Preparation of Wittig phosphonium salts at ambient temperature

W. G. Dauben, J. Gerdes, R. Bunce, 1984 .

Studies on vitamin D (calciferol and its analogs). 22. Synthesis and thermolysis of A-norvinylallenes related to vitamin D

J. Gerdes, W. Okamura, P. Condran, 1981 .

Organic reactions at high pressure. A mild method for the placement of protecting groups on hindered and sensitive alcohols

W. G. Dauben, J. Gerdes, R. Bunce, 1984 .

Synthesis of high specific activity radiohalogenated amphetamine analogues for studies of the serotonin 5‐HT2 receptor

C. Mathis, J. Gerdes, A. Shulgin, 1989 .

Novel lavendamycin analogues as antitumor agents: synthesis, in vitro cytotoxicity, structure-metabolism, and computational molecular modeling studies with NAD(P)H:quinone oxidoreductase 1.

J. Gerdes, D. Holley, H. Seradj, 2005, Journal of medicinal chemistry.

Nucleophilic aromatic substitution reactions with the fluoride ion : formation of 5-fluoro-indanones and indandiones related to atipamezole

C. Mathis, J. Gerdes, J. Enas, 1993 .

Novel Organophosphate Ligand O-(2-Fluoroethyl)-O-(p-Nitrophenyl)Methylphosphonate: Synthesis, Hydrolytic Stability and Analysis of the Inhibition and Reactivation of Cholinesterases.

C. Thompson, J. Gerdes, Chih-Kai Chao, 2016, Chemical research in toxicology.

The inhibition, reactivation and mechanism of VX-, sarin-, fluoro-VX and fluoro-sarin surrogates following their interaction with HuAChE and HuBuChE.

C. Thompson, J. Gerdes, Chih-Kai Chao, 2018, Chemico-biological interactions.

Synthesis and evaluation of high affinity, aryl-substituted [18F]fluoropropylbenzamides for dopamine D-2 receptor studies.

W. Jagust, C. Mathis, J. Gerdes, 1992, International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology.

Biological Distribution and Metabolic Profiles of Carbon-11 and Fluorine-18 Tracers of VX- and Sarin-Analogs in Sprague–Dawley Rats

H. VanBrocklin, C. Thompson, J. Gerdes, 2020, Chemical research in toxicology.

Development of a homology model for clade A human immunodeficiency virus type 1 gp120 to localize temporal substitutions arising in recently infected women.

J. Gerdes, M. Poss, R. Biek, 2004, The Journal of general virology.

A novel fluorine-18 β-fluoroethoxy organophosphate positron emission tomography imaging tracer targeted to central nervous system acetylcholinesterase.

Michael R. Braden, H. VanBrocklin, C. Thompson, 2014, ACS chemical neuroscience.

Inhibition of acetylcholinesterase by chromophore-linked fluorophosphonates.

Michael R. Braden, C. Thompson, J. Gerdes, 2010, Bioorganic & medicinal chemistry letters.

Tetrapeptide inhibitors of the glutamate vesicular transporter (VGLUT).

C. Thompson, J. Gerdes, S. Patel, 2007, Bioorganic & medicinal chemistry letters.