Jiake Xu

J. Cornish, K. Callon, A. Grey, 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Proteasome inhibitors impair RANKL‐induced NF‐κB activity in osteoclast‐like cells via disruption of p62, TRAF6, CYLD, and IκBα signaling cascades

J. Walsh, N. Pavlos, Jiake Xu, 2009, Journal of cellular physiology.

The Molecular Structure and Role of Humanin in Neural and Skeletal Diseases, and in Tissue Regeneration

Jiake Xu, Yu-liang Mai, Samuel Bennett, 2022, Frontiers in Cell and Developmental Biology.

Mechanical Stress Regulates Bone Metabolism Through MicroRNAs

Xi Chen, Lingli Zhang, Jun Zou, 2016, Journal of cellular physiology.

Assessment of Bone, Cartilage, Tendon and Bone Cells by Confocal Laser Scanning Microscopy

Jiake Xu, M. Zheng, M. Zheng, 2007 .

Cycloastragenol Attenuates Osteoclastogenesis and Bone Loss by Targeting RANKL-Induced Nrf2/Keap1/ARE, NF-κB, Calcium, and NFATc1 Pathways

W. He, Chao Ma, Jiake Xu, 2022, Frontiers in Pharmacology.

A delivery system specifically approaching bone resorption surfaces to facilitate therapeutic modulation of microRNAs in osteoclasts.

Xiaojuan He, Zicai Liang, Jiake Xu, 2015, Biomaterials.

Elastin fibers display a versatile microfibril network in articular cartilage depending on the mechanical microenvironments

T. B. Kirk, Jiake Xu, B. He, 2013, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Osteoimmunomodulatory injectable Lithium-Heparin hydrogel with Microspheres/TGF-β1 delivery promotes M2 macrophage polarization and osteogenesis for guided bone regeneration

Jiake Xu, Zhouyuan Yang, Xin Zhao, 2022, Chemical Engineering Journal.

Neohesperidin suppresses osteoclast differentiation, bone resorption and ovariectomised-induced osteoporosis in mice

A. Qin, Xixi Lin, Jinmin Zhao, 2017, Molecular and Cellular Endocrinology.

Synthesis of Janus Au nanorods/polydivinylbenzene hybrid nanoparticles for chemo-photothermal therapy.

T. B. Kirk, Yunfeng Shi, Jianping Wu, 2018, Journal of materials chemistry. B.

Brainstem iron overload and injury in a rat model of brainstem hemorrhage.

Jiake Xu, Lu Ma, Hao Li, 2020, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

Rosuvastatin Nanomicelles Target Neuroinflammation and Improve Neurological Deficit in a Mouse Model of Intracerebral Hemorrhage

Jiake Xu, Jianguo Xu, Wencheng Zhou, 2021, International journal of nanomedicine.

TNF-α inhibits SATB2 expression and osteoblast differentiation through NF-κB and MAPK pathways

Jiake Xu, Chuandong Wang, Xiaoling Zhang, 2017, Oncotarget.

CYT387, a JAK-Specific Inhibitor Impedes Osteoclast Activity and Oophorectomy-Induced Osteoporosis via Modulating RANKL and ROS Signaling Pathways

Jiake Xu, Liwei Wu, Jing Li, 2022, Frontiers in Pharmacology.

Loureirin B suppresses RANKL-induced osteoclastogenesis and ovariectomized osteoporosis via attenuating NFATc1 and ROS activities

Jiake Xu, Jennifer Tickner, Qingwen Zhang, 2019, Theranostics.

Salidroside promotes rat spinal cord injury recovery by inhibiting inflammatory cytokine expression and NF‐κB and MAPK signaling pathways

Shaohui Zong, A. Qin, Jinmin Zhao, 2019, Journal of cellular physiology.

MiR-214 Attenuates the Osteogenic Effects of Mechanical Loading on Osteoblasts.

Lingli Zhang, Jun Zou, Jiake Xu, 2019, International journal of sports medicine.

The molecular structure and function of sorting nexin 10 in skeletal disorders, cancers, and other pathological conditions

N. Pavlos, Jinmin Zhao, Jiake Xu, 2020, Journal of cellular physiology.

Sugar transporter Slc37a2 regulates bone metabolism via a dynamic tubular lysosomal network in osteoclasts

R. Teasdale, Laila N. Abudulai, K. Søe, 2022, bioRxiv.

The Effects of Asprosin on Exercise-Intervention in Metabolic Diseases

Xi Chen, Jun Zou, Jiake Xu, 2022, Frontiers in Physiology.

Osteoclastic Bone Resorption Trafficking Pathway That Is Required for Rab3D Regulates a Novel Vesicular

R. Jahn, S. Teitelbaum, F. Ross, 2014 .

Rab3D Regulates a Novel Vesicular Trafficking Pathway That Is Required for Osteoclastic Bone Resorption

R. Jahn, S. Teitelbaum, F. Ross, 2005, Molecular and Cellular Biology.

Patchouli Alcohol Modulates the Pregnancy X Receptor/Toll-like Receptor 4/Nuclear Factor Kappa B Axis to Suppress Osteoclastogenesis

Jiake Xu, Ziyi Chen, Jian-Feng Zhang, 2021, Frontiers in Pharmacology.

The molecular structure and role of CCL2 (MCP‐1) and C‐C chemokine receptor CCR2 in skeletal biology and diseases

Mei Liu, Jiake Xu, K. Pfleger, 2021, Journal of cellular physiology.

Star-Shaped Amphiphilic Hyperbranched Polyglycerol Conjugated with Dendritic Poly(l-lysine) for the Codelivery of Docetaxel and MMP-9 siRNA in Cancer Therapy.

T. B. Kirk, Changyong Wang, Jiake Xu, 2016, ACS applied materials & interfaces.

Cytoplasmic hnRNPK interacts with GSK3β and is essential for the osteoclast differentiation

Qing‐Yu He, Xuejuan Gao, Jiake Xu, 2015, Scientific Reports.

Chondromodulin-1 in health, osteoarthritis, cancer, and heart disease

V. Rosen, Huazi Xu, Jiake Xu, 2019, Cellular and Molecular Life Sciences.

Rhoifolin ameliorates titanium particle‐stimulated osteolysis and attenuates osteoclastogenesis via RANKL‐induced NF‐κB and MAPK pathways

Xixi Lin, Jinmin Zhao, Jiake Xu, 2019, Journal of cellular physiology.

Evidence of reciprocal regulation between the high extracellular calcium and RANKL signal transduction pathways in RAW cell derived osteoclasts

J. Steer, N. Pavlos, Jiake Xu, 2005, Journal of cellular physiology.

Tctex-1, a Novel Interaction Partner of Rab3D, Is Required for Osteoclastic Bone Resorption

C. Sung, R. Jahn, N. Pavlos, 2011, Molecular and Cellular Biology.

Gene expression of glucocorticoid receptor α and β in giant cell tumour of bone: evidence of glucocorticoid-stimulated osteoclastogenesis by stromal-like tumour cells

S. Kumta, Jiake Xu, M. Zheng, 2001, Molecular and Cellular Endocrinology.

Roles of neurotrophins in skeletal tissue formation and healing

Jiake Xu, Yu-Wen Su, Xin-Fu Zhou, 2018, Journal of cellular physiology.

Codelivery of Epigallocatechin-3-Gallate and Diallyl Trisulfide by Near-Infrared Light-Responsive Mesoporous Polydopamine Nanoparticles for Enhanced Antitumor Efficacy.

Jiake Xu, Wei Xue, Qunfeng Liu, 2020, International journal of pharmaceutics.

Calmodulin interacts with Rab3D and modulates osteoclastic bone resorption

Huazi Xu, N. Pavlos, Jiake Xu, 2016, Scientific Reports.

Paclitaxel inhibits osteoclast formation and bone resorption via influencing mitotic cell cycle arrest and RANKL‐induced activation of NF‐κB and ERK

J. Steer, N. Pavlos, Jiake Xu, 2012, Journal of cellular biochemistry.

Thapsigargin Modulates Osteoclastogenesis Through the Regulation of RANKL‐Induced Signaling Pathways and Reactive Oxygen Species Production

J. Steer, Jiake Xu, M. Zheng, 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Steroid-induced osteonecrosis of the femoral head reveals enhanced reactive oxygen species and hyperactive osteoclasts

N. Pavlos, Jiake Xu, Qingwen Zhang, 2020, International journal of biological sciences.

Biocompatibility and cellular uptake mechanisms of poly(N-isopropylacrylamide) in different cells

Changyong Wang, Jianping Wu, Jiake Xu, 2017 .

SC-514, a selective inhibitor of IKKβ attenuates RANKL-induced osteoclastogenesis and NF-κB activation.

N. Pavlos, Qiong Gu, Jun Xu, 2013, Biochemical pharmacology.

Fibrochondrogenic differentiation potential of tendon-derived stem/progenitor cells from human patellar tendon

Jiake Xu, S. Fu, Zhihe Liu, 2019, Journal of orthopaedic translation.

Osteoimmunological insights into the pathogenesis of ankylosing spondylitis

Jun Zou, Jiake Xu, Yu Yuan, 2021, Journal of cellular physiology.

Macrophages release plasma membrane-derived particles rich in accessible cholesterol

S. Young, H. Riezman, P. Tontonoz, 2018, Proceedings of the National Academy of Sciences.

Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference–based bone anabolic strategy

Yu Cao, Xiaojuan He, Hui Li, 2015, Nature Medicine.

Sesquiterpene Lactone Parthenolide Blocks Lipopolysaccharide‐Induced Osteolysis Through the Suppression of NF‐κB Activity

J. Steer, Jiake Xu, M. Zheng, 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Divergent effects of endogenous and exogenous GILZ in models of inflammation and arthritis

E. Morand, Jiake Xu, V. Escriou, 2014 .

Divergent effects of endogenous and exogenous glucocorticoid-induced leucine zipper in animal models of inflammation and arthritis.

E. Morand, Jiake Xu, V. Escriou, 2013, Arthritis and rheumatism.

Endothelial cells produce angiocrine factors to regulate bone and cartilage via versatile mechanisms

V. Rosen, Huazi Xu, Jiake Xu, 2020, Theranostics.

Type II Collagen Sponges Facilitate Tendon Stem/Progenitor Cells to Adopt More Chondrogenic Phenotypes and Promote the Regeneration of Fibrocartilage-Like Tissues in a Rabbit Partial Patellectomy Model

Jiake Xu, Zhihe Liu, Shengnan Qin, 2021, Frontiers in Cell and Developmental Biology.

PIP5k1β controls bone homeostasis through modulating both osteoclast and osteoblast differentiation

Jiake Xu, Chuandong Wang, Xiaoling Zhang, 2018, bioRxiv.

Macrophage migration inhibitory factor is essential for osteoclastogenic mechanisms in vitro and in vivo mouse model of arthritis.

G. Fingerle-Rowson, R. Bucala, E. Morand, 2015, Cytokine.

PEGylation of Deferoxamine for Improving the Stability, Cytotoxicity, and Iron-Overload in an Experimental Stroke Model in Rats

Jiake Xu, Rui Zhong, Meng Tian, 2020, Frontiers in Bioengineering and Biotechnology.

Massage Alleviates Delayed Onset Muscle Soreness after Strenuous Exercise: A Systematic Review and Meta-Analysis

Rong Zhu, Jun Zou, Jiake Xu, 2017, Front. Physiol..

Cloning, Sequencing, and Functional Characterization of the Rat Homologue of Receptor Activator of NF‐κB Ligand

S. Wysocki, Jiake Xu, M. Zheng, 2000 .

Bafilomycin A1 Attenuates Osteoclast Acidification and Formation, Accompanied by Increased Levels of SQSTM1/p62 Protein

Hua-zi Xu, J. Walsh, N. Pavlos, 2016, Journal of cellular biochemistry.

Deficiency of sorting nexin 10 prevents bone erosion in collagen-induced mouse arthritis through promoting NFATc1 degradation

W. Shen, Chun Zhou, Jiake Xu, 2015, Annals of the rheumatic diseases.

Triptolide inhibits osteoclast formation, bone resorption, RANKL-mediated NF-қB activation and titanium particle-induced osteolysis in a mouse model

N. Pavlos, Jun Xu, Jinmin Zhao, 2015, Molecular and Cellular Endocrinology.

Disruption of the dynein‐dynactin complex unveils motor‐specific functions in osteoclast formation and bone resorption

N. Pavlos, Jiake Xu, E. Khor, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Cytoplasmic Terminus of Vacuolar Type Proton Pump Accessory Subunit Ac45 Is Required for Proper Interaction with V0 Domain Subunits and Efficient Osteoclastic Bone Resorption*

N. Pavlos, Jiake Xu, K. Eidne, 2008, Journal of Biological Chemistry.

Naringin abrogates osteoclastogenesis and bone resorption via the inhibition of RANKL‐induced NF‐κB and ERK activation

Jiake Xu, M. Zheng, E. Ang, 2011, FEBS letters.

Caffeic acid phenethyl ester, an active component of honeybee propolis attenuates osteoclastogenesis and bone resorption via the suppression of RANKL‐induced NF‐κB and NFAT activity

J. Steer, N. Pavlos, Jiake Xu, 2009, Journal of cellular physiology.

p62 ubiquitin binding-associated domain mediated the receptor activator of nuclear factor-kappaB ligand-induced osteoclast formation: a new insight into the pathogenesis of Paget's disease of bone.

N. Pavlos, Jiake Xu, M. Zheng, 2006, The American journal of pathology.

Hymenialdisine: A Marine Natural Product That Acts on Both Osteoblasts and Osteoclasts and Prevents Estrogen‐Dependent Bone Loss in Mice

Jinmin Zhao, Jiake Xu, Rohan A. Davis, 2020, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Evaluation of N-phosphonium chitosan as a novel vaccine carrier for intramuscular immunization

Jiake Xu, Wei Xue, Zong-hua Liu, 2017, Journal of biomaterials applications.

Choline Kinase β Mutant Mice Exhibit Reduced Phosphocholine, Elevated Osteoclast Activity, and Low Bone Mass*

N. Pavlos, Jiake Xu, L. Hool, 2014, The Journal of Biological Chemistry.

The role of glial cell line‐derived neurotrophic factor family member artemin in neurological disorders and cancers

Huazi Xu, Jiake Xu, Samuel Bennett, 2020, Cell proliferation.

Alternative splicing of leptin receptor overlapping transcript in osteosarcoma

S. Kõks, A. Märtson, Jiake Xu, 2020, Experimental biology and medicine.

Molecular structure and function of microfibrillar‐associated proteins in skeletal and metabolic disorders and cancers

Huazi Xu, Jiake Xu, L. Ye, 2020, Journal of cellular physiology.

Helvolic acid attenuates osteoclast formation and function via suppressing RANKL‐induced NFATc1 activation

Jinmin Zhao, Jiake Xu, Jennifer Tickner, 2018, Journal of cellular physiology.

Single-Cell RNA Sequencing Reveals the Difference in Human Normal and Degenerative Nucleus Pulposus Tissue Profiles and Cellular Interactions

Weihua Luo, X. Yao, Jiake Xu, 2022, Frontiers in Cell and Developmental Biology.

A Novel Mutation (K378X) in the Sequestosome 1 Gene Associated With Increased NF‐κB Signaling and Paget's Disease of Bone With a Severe Phenotype

J. Walsh, J. Steer, Jiake Xu, 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Sequestosome 1 Mutations in Paget's Disease of Bone in Australia: Prevalence, Genotype/Phenotype Correlation, and a Novel Non‐UBA Domain Mutation (P364S) Associated With Increased NF‐κB Signaling Without Loss of Ubiquitin Binding

J. Walsh, A. Magno, Jiake Xu, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Isoliensinine Suppresses Osteoclast Formation Through NF-κB Signaling Pathways and Relieves Ovariectomy-Induced Bone Loss

Xinli Zhan, Jiake Xu, Yun Liu, 2022, Frontiers in Pharmacology.

Asiaticoside, a component of Centella asiatica attenuates RANKL‐induced osteoclastogenesis via NFATc1 and NF‐κB signaling pathways

Jiake Xu, Xiaorui Han, Lin Zhou, 2018, Journal of cellular physiology.

Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats.

L. Butler, C. Prestidge, Di Chen, 2018, Bone.

Connecting Versatile lncRNAs with Heterogeneous Nuclear Ribonucleoprotein K and Pathogenic Disorders.

Jiake Xu, Ziyi Wang, Sipin Zhu, 2019, Trends in biochemical sciences.

Melphalan modifies the bone microenvironment by enhancing osteoclast formation

Gholamreza Haffari, J. Pettitt, P. Croucher, 2017, Oncotarget.

The effects of biophysical stimulation on osteogenic differentiation and the mechanisms from ncRNAs

Jun Zou, Jiake Xu, Jianmin Guo, 2021, Cell biochemistry and function.

Molecular structure, expression, and functional role of Clec11a in skeletal biology and cancers

Lingli Zhang, Jun Zou, Jiake Xu, 2020, Journal of cellular physiology.

Thiaplakortone B attenuates RANKL-induced NF-κB and MAPK signaling and dampens OVX-induced bone loss in mice.

Jiake Xu, Rohan A. Davis, Haiming Jin, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Chrysin Protects Against Titanium Particle-Induced Osteolysis by Attenuating Osteoclast Formation and Function by Inhibiting NF-κB and MAPK Signaling

Jinmin Zhao, Jiake Xu, Li Li, 2022, Frontiers in Pharmacology.

Lonafarnib Inhibits Farnesyltransferase via Suppressing ERK Signaling Pathway to Prevent Osteoclastogenesis in Titanium Particle-Induced Osteolysis

Shiyao Gao, Jinmin Zhao, Jiake Xu, 2022, Frontiers in Pharmacology.

PKC-δ deficiency in B cells displays osteopenia accompanied with upregulation of RANKL expression and osteoclast–osteoblast uncoupling

S. Zheng, Jiake Xu, Jennifer Tickner, 2020, Cell Death & Disease.

Inhibitory effects of biochanin A on titanium particle‐induced osteoclast activation and inflammatory bone resorption via NF‐κB and MAPK pathways

Xixi Lin, Jinmin Zhao, Jiake Xu, 2020, Journal of cellular physiology.

Betulinic Acid Protects From Bone Loss in Ovariectomized Mice and Suppresses RANKL-Associated Osteoclastogenesis by Inhibiting the MAPK and NFATc1 Pathways

Jinmin Zhao, Jiake Xu, Liwei Wu, 2020, Frontiers in Pharmacology.

Jatrophane Diterpenoids from Euphorbia esula as Inhibitors of RANKL-Induced Osteoclastogenesis.

Qiong Gu, Jun Xu, Jiake Xu, 2020, Journal of natural products.

Asiatic Acid Inhibits OVX-Induced Osteoporosis and Osteoclastogenesis Via Regulating RANKL-Mediated NF-κb and Nfatc1 Signaling Pathways

Jiake Xu, Xiaorui Han, Lin Zhou, 2020, Frontiers in Pharmacology.

Ellagic acid protects ovariectomy‐induced bone loss in mice by inhibiting osteoclast differentiation and bone resorption

Xixi Lin, Jinmin Zhao, Jiake Xu, 2020, Journal of cellular physiology.

Dracorhodin perchlorate inhibits osteoclastogenesis through repressing RANKL‐stimulated NFATc1 activity

Jiake Xu, Chao Ma, Qingwen Zhang, 2020, Journal of cellular and molecular medicine.

Cytochalasin Z11 inhibits RANKL-induced osteoclastogenesis via suppressing NFATc1 activation

Jinmin Zhao, Jiake Xu, R. Tan, 2019, RSC advances.

Pseurotin A Inhibits Osteoclastogenesis and Prevents Ovariectomized-Induced Bone Loss by Suppressing Reactive Oxygen Species

Jinmin Zhao, Jiake Xu, S. Fan, 2019, Theranostics.

Cumambrin A prevents OVX‐induced osteoporosis via the inhibition of osteoclastogenesis, bone resorption, and RANKL signaling pathways

Qiong Gu, Jun Xu, Jinmin Zhao, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Diosmetin inhibits osteoclast formation and differentiation and prevents LPS‐induced osteolysis in mice

Xixi Lin, Jinmin Zhao, Jiake Xu, 2018, Journal of cellular physiology.

Cistanche deserticola polysaccharide attenuates osteoclastogenesis and bone resorption via inhibiting RANKL signaling and reactive oxygen species production

Jiake Xu, S. Dong, Jennifer Tickner, 2018, Journal of cellular physiology.

Lumichrome inhibits osteoclastogenesis and bone resorption through suppressing RANKL‐induced NFAT activation and calcium signaling

Jiake Xu, S. Dong, R. Tan, 2018, Journal of cellular physiology.

PIP5k1 β controls bone homeostasis through modulating both osteoclast and osteoblast differentiation

Jiake Xu, Chuandong Wang, Xiaoling Zhang, 2018, bioRxiv.

Artesunate inhibits RANKL‐induced osteoclastogenesis and bone resorption in vitro and prevents LPS‐induced bone loss in vivo

Shaohui Zong, Xixi Lin, Jinmin Zhao, 2018, Journal of cellular physiology.

Nitidine chloride prevents OVX-induced bone loss via suppressing NFATc1-mediated osteoclast differentiation

A. Qin, Xixi Lin, Jiake Xu, 2016, Scientific Reports.

Amyloid β Peptide Enhances RANKL-Induced Osteoclast Activation through NF-κB, ERK, and Calcium Oscillation Signaling

Jiake Xu, Lin Zhou, D. Teguh, 2016, International journal of molecular sciences.

Berberine Sulfate Attenuates Osteoclast Differentiation through RANKL Induced NF-κB and NFAT Pathways

Mingli Yang, Jun Xu, Jinmin Zhao, 2015, International journal of molecular sciences.

HtrA1 is upregulated during RANKL‐induced osteoclastogenesis, and negatively regulates osteoblast differentiation and BMP2‐induced Smad1/5/8, ERK and p38 phosphorylation

V. Rosen, Xinghuo Wu, Jinmin Zhao, 2014, FEBS letters.

Growth Factors , Cytokines , and Cell Cycle Molecules Methotrexate Chemotherapy Promotes Osteoclast Formation in the Long Bone of Rats via Increased Pro-Inflammatory Cytokines and Enhanced NF-B Activation

Jiake Xu, M. Scherer, E. Ang, 2012 .

Myocyte Enhancer Factor 2 and Microphthalmia-associated Transcription Factor Cooperate with NFATc1 to Transactivate the V-ATPase d2 Promoter during RANKL-induced Osteoclastogenesis*

J. Steer, N. Pavlos, Jiake Xu, 2009, Journal of Biological Chemistry.

12‐O‐tetradecanoylphorbol‐13‐acetate (TPA) Inhibits Osteoclastogenesis by Suppressing RANKL‐Induced NF‐κB Activation

J. Steer, Jiake Xu, M. Zheng, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

12-O-tetradecanoylphorbol-13-acetate (TPA) inhibits osteoclastogenesis by suppressing RANKL-induced NF-kappaB activation.

J. Steer, Jiake Xu, M. Zheng, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Alpinetin Ameliorates Bone Loss in LPS-induced Inflammation Osteolysis via ROS Mediated P38/PI3K signaling pathway.

Jiake Xu, Hui Wang, Yuangang Su, 2022, Pharmacological research.

NPNT is Expressed by Osteoblasts and Mediates Angiogenesis via the Activation of Extracellular Signal-regulated Kinase

V. Rosen, W. Erber, Huazi Xu, 2016, Scientific Reports.

Non-severe burn injury leads to depletion of bone volume that can be ameliorated by inhibiting TNF-α.

M. Fear, F. Wood, Jiake Xu, 2015, Burns : journal of the International Society for Burn Injuries.

Sinomenine down-regulates TLR4/TRAF6 expression and attenuates lipopolysaccharide-induced osteoclastogenesis and osteolysis.

Jiake Xu, Shuwen Liu, Xianglian Li, 2016, European journal of pharmacology.

Systemic Administration of Fibroblast Growth Factor 21 Improves the Recovery of Spinal Cord Injury (SCI) in Rats and Attenuates SCI-Induced Autophagy

Huazi Xu, Jiake Xu, L. Ye, 2021, Frontiers in Pharmacology.

Epidermal Stem Cells Cultured on Collagen-Modified Chitin Membrane Induce In Situ Tissue Regeneration of Full-Thickness Skin Defects in Mice

Jiake Xu, S. Mei, Zhihe Liu, 2014, PloS one.

Scutellarein inhibits RANKL‐induced osteoclast formation in vitro and prevents LPS‐induced bone loss in vivo

Xixi Lin, Jinmin Zhao, Jiake Xu, 2018, Journal of cellular physiology.

Parthenolide reduces empty lacunae and osteoclastic bone surface resorption induced by polyethylene particles in a murine calvarial model of peri-implant osteolysis.

E. Perilli, Jiake Xu, M. Cantley, 2015, Journal of biomedical materials research. Part A.

Expression and localization of extracellular matrix metalloproteinase inducer in giant cell tumor of bone

S. Kumta, Jiake Xu, M. Zheng, 2003, Journal of cellular biochemistry.

Prevention of Wear Particle-Induced Osteolysis by a Novel V-ATPase Inhibitor Saliphenylhalamide through Inhibition of Osteoclast Bone Resorption

A. Qin, N. Pavlos, Jiake Xu, 2012, PloS one.

Protein Cytl1: its role in chondrogenesis, cartilage homeostasis, and disease

V. Rosen, Huazi Xu, Jiake Xu, 2019, Cellular and Molecular Life Sciences.

AKT/GSK3β/NFATc1 and ROS signal axes are involved in AZD1390-mediated inhibitory effects on osteoclast and OVX-induced osteoporosis.

Jiake Xu, Yuangang Su, Qian Liu, 2022, International immunopharmacology.

Natural Compounds for the Treatment of Psoriatic Arthritis: A Proposal Based on Multi-Targeted Osteoclastic Regulation and on a Preclinical Study

Jinmin Zhao, Jiake Xu, S. Deng, 2017, JMIR research protocols.

Injectable and Self-Healing Hydrogels with Double-Dynamic Bond Tunable Mechanical, Gel-Sol Transition and Drug Delivery Properties for Promoting Periodontium Regeneration in Periodontitis.

T. B. Kirk, Jiake Xu, Wei Xue, 2021, ACS applied materials & interfaces.

The therapeutic effect of Fufang Zhenshu Tiaozhi (FTZ) on osteoclastogenesis and ovariectomized-induced bone loss: evidence from network pharmacology, molecular docking and experimental validation

Jiake Xu, Chenghong Ma, Ping Sun, 2022, Aging.

Coupling factors and exosomal packaging microRNAs involved in the regulation of bone remodelling

Huazi Xu, Jiake Xu, Ge Zhang, 2018, Biological reviews of the Cambridge Philosophical Society.

The y6 receptor suppresses bone resorption and stimulates bone formation in mice via a suprachiasmatic nucleus relay.

F. Driessler, Jiake Xu, Lei Zhang, 2016, Bone.

Osteoblast-derived EGFL6 couples angiogenesis to osteogenesis during bone repair

A. Qin, N. Pavlos, Jinmin Zhao, 2021, Theranostics.

Poria cocos polysaccharide attenuates RANKL-induced osteoclastogenesis by suppressing NFATc1 activity and phosphorylation of ERK and STAT3.

Jiake Xu, S. Dong, Jennifer Tickner, 2018, Archives of biochemistry and biophysics.

MAGED1 is a negative regulator of bone remodeling in mice.

Q. Pan, F. Wang, A. Qin, 2015, The American journal of pathology.

GdX/UBL4A null mice exhibit mild kyphosis and scoliosis accompanied by dysregulation of osteoblastogenesis and chondrogenesis

Jiake Xu, Jiao Liang, Yinyin Wang, 2018, Cell biochemistry and function.

Generation of induced pluripotent stem cell line, ZJUCHi002-A, from Charcot-Marie-Tooth disease type 2A (CMT2A) patient with a mutation of c.752C>T in MFN2.

Y. Li, Jiake Xu, Jianwei Pan, 2019, Stem cell research.

The role of SATB2 in skeletogenesis and human disease.

Jiake Xu, Xiaoling Zhang, K. Dai, 2014, Cytokine & growth factor reviews.

Retraction of: A005, a novel inhibitor of phosphatidylinositol 3-kinase/mammalian target of rapamycin, prevents osteosarcoma-induced osteolysis.

A. Qin, Xixi Lin, Jiake Xu, 2019, Carcinogenesis.

Role of Sostdc1 in skeletal biology and cancer

Xi Chen, Jiake Xu, Chenyu Zhu, 2022, Frontiers in Physiology.

Carnosic acid inhibits inflammation response and joint destruction on osteoclasts, fibroblast‐like synoviocytes, and collagen‐induced arthritis rats

Mei Liu, Jinmin Zhao, Jiake Xu, 2018, Journal of cellular physiology.

Hederagenin protects mice against ovariectomy-induced bone loss by inhibiting RANKL-induced osteoclastogenesis and bone resorption.

Xixi Lin, Jinmin Zhao, Jiake Xu, 2020, Life sciences.

Cyanidin Chloride inhibits ovariectomy‐induced osteoporosis by suppressing RANKL‐mediated osteoclastogenesis and associated signaling pathways

Xixi Lin, Mei Liu, N. Pavlos, 2018, Journal of cellular physiology.

Rab3D Regulates Vesicle Fusion in Osteoclasts

F. Ross, N. Pavlos, Jiake Xu, 1999 .

Protein kinase C delta null mice exhibit structural alterations in articular surface, intra-articular and subchondral compartments

T. B. Kirk, Jiake Xu, Wei Xue, 2015, Arthritis Research & Therapy.

The molecular structure and role of LECT2 or CHM‐II in arthritis, cancer, and other diseases

Mei Liu, Jiake Xu, Samuel Bennett, 2021, Journal of cellular physiology.

Molecular structure and the role of high‐temperature requirement protein 1 in skeletal disorders and cancers

Huazi Xu, Xinghuo Wu, Jiake Xu, 2019, Cell proliferation.

Generation of a human Charcot-Marie-Tooth disease type 1B (CMT1B) iPSC line, ZJUCHi001-A, with a mutation of c.292C>T in MPZ.

Y. Li, Jiake Xu, Haifeng Li, 2019, Stem cell research.

Anti-Osteoclast Effect of Exportin-1 Inhibitor Eltanexor on Osteoporosis Depends on Nuclear Accumulation of IκBα–NF-κB p65 Complex

Lili Tang, Jiake Xu, Jun-chun Chen, 2022, Frontiers in Pharmacology.

Dihydroartemisinin, an Anti‐Malaria Drug, Suppresses Estrogen Deficiency‐Induced Osteoporosis, Osteoclast Formation, and RANKL‐Induced Signaling Pathways

Mingli Yang, Xixi Lin, Jinmin Zhao, 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Evaluation of Insoluble Bone Gelatin as a Carrier for Enhancement of Osteogenic Protein-1-Induced Intertransverse Process Lumbar Fusion in a Rabbit Model

Jiake Xu, M. Zheng, K. Stoffel, 2008, Spine.

Sequestosome 1 mutations in Paget's disease of bone in Australia: Prevalence, genotype/phenotype correlation and a novel non-UBA domain mutation (P364S) associated with increased NF-κB signalling without loss of ubiquitin-binding

J. Walsh, A. Magno, Jiake Xu, 2009 .

Single-Cell Transcriptome Analysis Reveals Paraspeckles Expression in Osteosarcoma Tissues

Qingjun Wei, A. Fox, Jiake Xu, 2022, Cancer informatics.

Subcellular Partitioning of Arsenic Trioxide Revealed by Label-Free Imaging.

W. Chen, S. Young, P. Clode, 2022, Analytical chemistry.

Differential expression of extracellular-signal-regulated kinase 5 (ERK5) in normal and degenerated human nucleus pulposus tissues and cells.

Jiake Xu, Libing Dai, Dongping Ye, 2014, Biochemical and biophysical research communications.

Cajaninstilbene acid inhibits osteoporosis through suppressing osteoclast formation and RANKL‐induced signaling pathways

Jiake Xu, Jennifer Tickner, Zhi-Nan Hong, 2018, Journal of cellular physiology.

The versatile roles of odontogenic ameloblast-associated protein in odontogenesis, junctional epithelium regeneration and periodontal disease

O. Kujan, Jiake Xu, Samuel Bennett, 2022, Frontiers in Physiology.

Overexpression of hTERT extends replicative capacity of human nucleus pulposus cells, and protects against serum starvation‐induced apoptosis and cell cycle arrest

Jiake Xu, Libing Dai, Dongping Ye, 2012, Journal of cellular biochemistry.

Single-cell RNA sequencing reveals differential expression of EGFL7 and VEGF in giant-cell tumor of bone and osteosarcoma

Qingjun Wei, S. Kõks, Jiake Xu, 2022, Experimental biology and medicine.

Injectable Gelatin Hydrogel Suppresses Inflammation and Enhances Functional Recovery in a Mouse Model of Intracerebral Hemorrhage

Jiake Xu, Lu Ma, Hao Li, 2020, Frontiers in Bioengineering and Biotechnology.

Biological insights into the rapid tissue regeneration of freshwater crayfish and crustaceans

Jiake Xu, Samuel Bennett, Xiaoyong Hu, 2021, Cell biochemistry and function.

Electrochemical behavior of (Ti 1-x Nb x)5Si3 nanocrystalline films in simulated physiological media.

Jiake Xu, Jiang Xu, P. Munroe, 2014, Acta biomaterialia.

Double network shape memory hydrogels activated by near-infrared with high mechanical toughness, nontoxicity, and 3D printability

Dong Ma, Jiake Xu, Wei Xue, 2019, Chemical Engineering Journal.

Andrographolide Inhibits Ovariectomy-Induced Bone Loss via the Suppression of RANKL Signaling Pathways

Xixi Lin, Jinmin Zhao, Jiake Xu, 2015, International journal of molecular sciences.

Eriodictyol Inhibits RANKL‐Induced Osteoclast Formation and Function Via Inhibition of NFATc1 Activity

Mingli Yang, Jun Xu, Jinmin Zhao, 2016, Journal of cellular physiology.

Therapeutic Anabolic and Anticatabolic Benefits of Natural Chinese Medicines for the Treatment of Osteoporosis

Zhifeng Xiao, Jiake Xu, Jianbo He, 2019, Front. Pharmacol..

Targeted treatment for osteoarthritis: drugs and delivery system

Jun Zou, Jiake Xu, Wei Wu, 2021, Drug delivery.

Current research progress in targeted anti‐angiogenesis therapy for osteosarcoma

Jiake Xu, Yun Liu, Shijie Liao, 2021, Cell proliferation.

Advanced Genetic Approaches in Discovery and Characterization of Genes Involved With Osteoporosis in Mouse and Human

G. Morahan, Jinmin Zhao, Jiake Xu, 2019, Front. Genet..

Use of the collaborative cross gene mine mouse phenotype library to identify novel genes regulating bone mass and bone architecture

G. Morahan, Jiake Xu, B. Mullin, 2016 .

High-resolution measurements of the multilayer ultra-structure of articular cartilage and their translational potential

Thomas Brett Kirk, T. B. Kirk, Jiake Xu, 2014, Arthritis Research & Therapy.

In vitro Evaluation of Natural Marine Sponge Collagen as a Scaffold for Bone Tissue Engineering

N. Pavlos, Jiake Xu, Xiaoling Zhang, 2011, International journal of biological sciences.

Enhanced BMP signalling causes growth plate cartilage dysrepair in rats.

Jiake Xu, Liping Wang, Yu-Wen Su, 2021, Bone.

Microstructural and Compositional Features of the Fibrous and Hyaline Cartilage on the Medial Tibial Plateau Imply a Unique Role for the Hopping Locomotion of Kangaroo

T. B. Kirk, Jiake Xu, B. He, 2013, PloS one.

Hemostasis mechanism and applications of N‐alkylated chitosan sponge

T. B. Kirk, Changyong Wang, Jianping Wu, 2017 .

Epoxymicheliolide inhibits osteoclastogenesis and resists OVX-induced osteoporosis by suppressing ERK1/2 and NFATc1 signaling.

Jinmin Zhao, Jiake Xu, F. Long, 2022, International immunopharmacology.

The Effect of Exercise on the Prevention of Osteoporosis and Bone Angiogenesis

Jun Zou, Jiake Xu, Xiaoyan Shen, 2019, BioMed research international.

Fibrin sealant promotes migration and proliferation of human articular chondrocytes: possible involvement of thrombin and protease-activated receptors.

Jiake Xu, N. Pavlos, Jiake Xu, 2006, International journal of molecular medicine.

Autologous tenocyte therapy using porcine-derived bioscaffolds for massive rotator cuff defect in rabbits.

Jiake Xu, Allan Wang, Jiake Xu, 2007, Tissue engineering.

An emerging role of Prevotella histicola on estrogen-deficiency induced bone loss through the gut microbiota-bone axis

Jiake Xu, K. Jin, Lei Chen, 2020, bioRxiv.

Loss of Protein Kinase C-δ Protects against LPS-Induced Osteolysis Owing to an Intrinsic Defect in Osteoclastic Bone Resorption

K. Nakayama, N. Pavlos, Jiake Xu, 2013, PloS one.

Expression of caltrin in the baculovirus system and its purification in high yield and purity by cobalt (II) affinity chromatography.

Jiake Xu, M. Zheng, P. Akkari, 2003, Protein expression and purification.

Cepharanthine suppresses osteoclast formation by modulating the nuclear factor‐κB and nuclear factor of activated T‐cell signaling pathways

Xixi Lin, Jinmin Zhao, Jiake Xu, 2018, Journal of cellular biochemistry.

MiR‐214 is an important regulator of the musculoskeletal metabolism and disease

Jiake Xu, Jennifer Tickner, Lei-Lei Chen, 2018, Journal of cellular physiology.

Guidelines for clinical diagnosis and treatment of osteonecrosis of the femoral head in adults (2019 version)

W. Lineaweaver, Shin-Yoon Kim, S. Goodman, 2020, Journal of orthopaedic translation.

Angiogenic factors in bone local environment.

V. Rosen, W. Erber, Jiake Xu, 2013, Cytokine & growth factor reviews.

Molecular structure and differential function of choline kinases CHKα and CHKβ in musculoskeletal system and cancer.

Jun Zou, Jiake Xu, Jennifer Tickner, 2017, Cytokine & growth factor reviews.

Pharmacology-based molecular docking of 4-methylcatechol and its role in RANKL-mediated ROS/Keap1/Nrf2 signalling axis and osteoclastogenesis.

Jiake Xu, Liwei Wu, Jing Li, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

The role of EGFL7 as an angiogenesis regulator in cancer and skeletal system

Jiake Xu, Xiaorui Han, Lin Zhou, 2019 .

EGFL7: Master regulator of cancer pathogenesis, angiogenesis and an emerging mediator of bone homeostasis

Jiake Xu, Xiaorui Han, Lin Zhou, 2018, Journal of cellular physiology.

STAT3 and its targeting inhibitors in osteosarcoma

Xinli Zhan, Jiake Xu, Yun Liu, 2020, Cell proliferation.

The emerging role of NPNT in tissue injury repair and bone homeostasis

Jiake Xu, Jennifer Tickner, Lei-Lei Chen, 2018, Journal of cellular physiology.

Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts

F. Dudbridge, K. Zhu, J. Walsh, 2020, Genome Biology.

Isosinensetin alleviates estrogen deficiency-induced osteoporosis via suppressing ROS-mediated NF-κB/MAPK signaling pathways.

Jiake Xu, Yuangang Su, Qian Liu, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Inhibitory Effects of Rhaponticin on Osteoclast Formation and Resorption by Targeting RANKL-Induced NFATc1 and ROS Activity

Jiake Xu, Zhifeng Xiao, Jianbo He, 2021, Frontiers in Pharmacology.

Oroxylin A reduces osteoclast formation and bone resorption via suppressing RANKL-induced ROS and NFATc1 activation.

Jinmin Zhao, Jiake Xu, X. Feng, 2021, Biochemical pharmacology.

Morin attenuates osteoclast formation and function by suppressing the NF‐κB, MAPK and calcium signalling pathways

Jiake Xu, Xiangyang Wang, Haiming Jin, 2021, Phytotherapy research : PTR.

A missense mutation sheds light on a novel structure–function relationship of RANKL

N. Pavlos, Jinmin Zhao, Jiake Xu, 2020, Journal of cellular physiology.

Onc201 reduces osteoclastogenesis and prevents ovariectomy-induced bone loss via inhibiting RANKL-induced NFATc1 activation and the integrin signaling pathway.

Jiake Xu, Liwei Wu, Jing Li, 2022, European journal of pharmacology.

Mangiferin attenuates osteoclastogenesis, bone resorption, and RANKL‐induced activation of NF‐κB and ERK

Jiake Xu, E. Ang, Xiaohong Yang, 2011, Journal of cellular biochemistry.

AAV2-mediated and hypoxia response element-directed expression of bFGF in neural stem cells showed therapeutic effects on spinal cord injury in rats

Huazi Xu, Jiake Xu, W. Ni, 2021, Cell Death & Disease.

Analysis of scRNA-seq and bulk RNA-seq demonstrates the effects of EVI2B or CD361 on CD8+ T cells in osteosarcoma

Xinli Zhan, Qingjun Wei, Jiake Xu, 2022, Experimental biology and medicine.

Single-Cell Transcriptomics Reveals the Complexity of the Tumor Microenvironment of Treatment-Naive Osteosarcoma

Xinli Zhan, Qingjun Wei, Zengming Xiao, 2021, Frontiers in Oncology.

The Emerging Role of MORC Family Proteins in Cancer Development and Bone Homeostasis

Jiake Xu, Jennifer Tickner, Wei He, 2017, Journal of cellular physiology.

microRNA‐103a Functions as a Mechanosensitive microRNA to Inhibit Bone Formation Through Targeting Runx2

Y. Huang, Jiake Xu, Xiaodong Chen, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation

Xiaojuan He, D. Guo, Zicai Liang, 2016, Nature Communications.

Single-Cell RNA Sequencing Reveals the Migration of Osteoclasts in Giant Cell Tumor of Bone

Qingjun Wei, Jiake Xu, Jie Ma, 2021, Frontiers in Oncology.

Zoledronic Acid: Pleiotropic Anti-Tumor Mechanism and Therapeutic Outlook for Osteosarcoma.

A. Qin, Jiake Xu, K. Dai, 2018, Current drug targets.

The Role of Irisin in Exercise-Mediated Bone Health

Jun Zou, Jiake Xu, Lifei Liu, 2021, Frontiers in Cell and Developmental Biology.

Folate-targeting redox hyperbranched poly(amido amine)s delivering MMP-9 siRNA for cancer therapy.

Changyong Wang, Jiake Xu, D. Ma, 2016, Journal of materials chemistry. B.

New physiological insights into the phenomena of deer antler: A unique model for skeletal tissue regeneration

Jiake Xu, Samuel Bennett, Xiaoyong Hu, 2020, Journal of orthopaedic translation.

Conditional Knockout of PKC-δ in Osteoclasts Favors Bone Mass Accrual in Males Due to Decreased Osteoclast Function

B. Liu, A. Qin, Jiake Xu, 2020, Frontiers in Cell and Developmental Biology.

Light-Triggered Biomimetic Nanoerythrocyte for Tumor-Targeted Lung Metastatic Combination Therapy of Malignant Melanoma.

Jiake Xu, Wei Xue, Xin Ji, 2018, Small.

Versatile subtypes of pericytes and their roles in spinal cord injury repair, bone development and repair

Huazi Xu, Jian Xiao, Jiake Xu, 2022, Bone Research.

Bioreactor design for tendon/ligament engineering.

Jonas Rubenson, David G Lloyd, T. B. Kirk, 2013, Tissue engineering. Part B, Reviews.

Scaffolds for tendon and ligament repair: review of the efficacy of commercial products

Jiake Xu, Allan Wang, Jimin Chen, 2009, Expert review of medical devices.

A conceptual framework for computational models of Achilles tendon homeostasis

Jonas Rubenson, Justin W. Fernandez, Justin Fernandez, 2013, Wiley interdisciplinary reviews. Systems biology and medicine.

Single-cell RNA-seq identification of four differentially expressed survival-related genes by a TARGET: Osteosarcoma database analysis

Qingjun Wei, S. Kõks, Jiake Xu, 2022, Experimental biology and medicine.

Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation

Xuejuan Gao, Jiake Xu, D. Tang, 2020, Aging.

An emerging role of Prevotella histicola on estrogen deficiency-induced bone loss through the gut microbiota-bone axis in postmenopausal women and in ovariectomized mice.

Jiake Xu, K. Jin, Lei Chen, 2021, The American journal of clinical nutrition.

The Role of Long Non-coding RNA, Nuclear Enriched Abundant Transcript 1 (NEAT1) in Cancer and Other Pathologies

Jun Zou, Jiake Xu, Samuel Bennett, 2021, Biochemical Genetics.

The emerging roles of hnRNPK

A. Fox, Jiake Xu, Wei Xue, 2020, Journal of cellular physiology.

Morc3 mutant mice exhibit reduced cortical area and thickness, accompanied by altered haematopoietic stem cells niche and bone cell differentiation

Jiake Xu, D. Teguh, Jennifer Tickner, 2016, Scientific Reports.

Current research on pharmacologic and regenerative therapies for osteoarthritis

Jiake Xu, H. Ouyang, C. Dass, 2016, Bone Research.

Sugar transporter Slc37a2 regulates bone metabolism in mice via a tubular lysosomal network in osteoclasts

R. Teasdale, Laila N. Abudulai, H. Takayanagi, 2023, Nature Communications.

Repression of human cytomegalovirus major immediate early gene expression by the cellular transcription factor CCAAT displacement protein.

Jiake Xu, Jiake Xu, E. Mocarski, 2008, Virology.

Corrigendum: NPNT is Expressed by Osteoblasts and Mediates Angiogenesis via the Activation of Extracellular Signal-regulated Kinase

V. Rosen, W. Erber, Huazi Xu, 2016, Scientific Reports.

Circular RNAs in childhood‐related diseases and cancers: A review

Jun Zou, Jiake Xu, Samuel Bennett, 2020, Cell biochemistry and function.

Expression Quantitative Trait Locus Study of Bone Mineral Density GWAS Variants in Human Osteoclasts

F. Dudbridge, K. Zhu, J. Walsh, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Emerging Trend in the Pharmacotherapy of Osteoarthritis

Jinmin Zhao, Jiake Xu, W. B. Robertson, 2019, Front. Endocrinol..

Notopterol Attenuates Estrogen Deficiency-Induced Osteoporosis via Repressing RANKL Signaling and Reactive Oxygen Species

Jiake Xu, Peng Chen, Junzheng Yang, 2021, Frontiers in Pharmacology.

Bajijiasu Abrogates Osteoclast Differentiation via the Suppression of RANKL Signaling Pathways through NF-κB and NFAT

Jiake Xu, Lin Zhou, Jennifer Tickner, 2017, International journal of molecular sciences.

Biocompatible hyperbranched polyglycerol modified β-cyclodextrin derivatives for docetaxel delivery.

T. B. Kirk, Jianping Wu, Jiake Xu, 2017, Materials science & engineering. C, Materials for biological applications.

Three-dimensional printing of shape memory hydrogels with internal structure for drug delivery.

Thomas Brett Kirk, T. B. Kirk, Dong Ma, 2018, Materials science & engineering. C, Materials for biological applications.

Receptor Activator of NF‐κB Ligand Promotes Proliferation of a Putative Mammary Stem Cell Unique to the Lactating Epithelium

N. Zeps, P. Rigby, Jiake Xu, 2012, Stem cells.

Achyranthes bidentata polysaccharide suppresses osteoclastogenesis and bone resorption via inhibiting RANKL signaling

Jiake Xu, S. Dong, Jennifer Tickner, 2018, Journal of cellular biochemistry.

Tiliroside is a new potential therapeutic drug for osteoporosis in mice

Xixi Lin, Jinmin Zhao, Jiake Xu, 2019, Journal of cellular physiology.

Natural bone collagen scaffold combined with autologous enriched bone marrow cells for induction of osteogenesis in an ovine spinal fusion model.

Jiake Xu, K. Dai, R. Day, 2009, Tissue engineering. Part A.

NF-kappaB modulators in osteolytic bone diseases.

Jiake Xu, M. Zheng, E. Ang, 2009, Cytokine & growth factor reviews.

The Fibrinogen/Albumin Ratio Index as an Independent Prognostic Biomarker for Patients with Combined Hepatocellular Cholangiocarcinoma After Surgery

Jiake Xu, Hongwei Wang, Ye Feng, 2022, Cancer management and research.

CMAR_A_361462 1795..1806

Jiake Xu, Hongwei Wang, Ye Feng, 2022 .

TSC1 regulates osteoclast podosome organization and bone resorption through mTORC1 and Rac1/Cdc42

Mangmang Li, G. Xiao, Jiake Xu, 2017, Cell Death & Differentiation.

EGFL7 Is Expressed in Bone Microenvironment and Promotes Angiogenesis via ERK, STAT3, and Integrin Signaling Cascades

V. Rosen, W. Erber, Jinmin Zhao, 2015, Journal of cellular physiology.

Myopenia and Musculoskeletal Aging in Rheumatoid Arthritis

Jiake Xu, Dan-feng Xu, Lei Dai, 2020, Rheumatoid Arthritis - Other Perspectives towards a Better Practice.

Molecular Structure, Expression and Role of TAFA4 and its Receptor FPR1 in the Spinal Cord

Jiake Xu, Yu-liang Mai, Samuel Bennett, 2022, Frontiers in Cell and Developmental Biology.

Green synthesis of lignin nanoparticle in aqueous hydrotropic solution toward broadening the window for its processing and application

T. B. Kirk, Yunfeng Shi, Jianping Wu, 2018, Chemical Engineering Journal.

Matrix-induced autologous chondrocyte implantation (MACI): biological and histological assessment.

Jiake Xu, Jiake Xu, C. Willers, 2007, Tissue engineering.

Inhibition of furin by bone targeting superparamagnetic iron oxide nanoparticles alleviated breast cancer bone metastasis

Wenxin He, Xiankun Cao, A. Qin, 2020, Bioactive materials.

Sesamolin Protects Mice From Ovariectomized Bone Loss by Inhibiting Osteoclastogenesis and RANKL-Mediated NF-κB and MAPK Signaling Pathways

Jinmin Zhao, Jiake Xu, Zuoxing Wu, 2021, Frontiers in Pharmacology.

CHIP/Stub1 functions as a tumor suppressor and represses NF-κB-mediated signaling in colorectal cancer.

Jun Yu, N. Zeps, J. Sung, 2014, Carcinogenesis.

The therapeutic effect and mechanism of parthenolide in skeletal disease, cancers, and cytokine storm

O. Kujan, Jiake Xu, R. Tan, 2023, Frontiers in Pharmacology.

Pectolinarigenin prevents bone loss in ovariectomized mice and inhibits RANKL‐induced osteoclastogenesis via blocking activation of MAPK and NFATc1 signaling

Jinmin Zhao, Jiake Xu, Yu Xiao, 2019, Journal of cellular physiology.

Effects of follicle-stimulating hormone on fat metabolism and cognitive impairment in women during menopause

Jun Zou, Jiake Xu, Samuel Bennett, 2022, Frontiers in Physiology.

Galanin family peptides: Molecular structure, expression and roles in the neuroendocrine axis and in the spinal cord

Jiake Xu, Shengnan Qin, Yu-liang Mai, 2022, Frontiers in Endocrinology.

Monocrotaline Suppresses RANKL-Induced Osteoclastogenesis In Vitro and Prevents LPS-Induced Bone Loss In Vivo

Shaohui Zong, Jinmin Zhao, Jiake Xu, 2018, Cellular Physiology and Biochemistry.

Protein Kinase C Inhibitor, GF109203X Attenuates Osteoclastogenesis, Bone Resorption and RANKL‐Induced NF‐κB and NFAT Activity

Jinmin Zhao, Jiake Xu, Ge Zhang, 2015, Journal of cellular physiology.

Discovery of new inhibitors against both NF-κB and osteoclastogenesis from in-house library with α, β-unsaturated-enone fragment.

Dane Huang, Qiong Gu, Jun Xu, 2019, Bioorganic chemistry.

Calcium/calmodulin‐dependent kinase activity is required for efficient induction of osteoclast differentiation and bone resorption by receptor activator of nuclear factor kappa B ligand (RANKL)

Ping Zhang, Jiake Xu, Ping Zhang, 2007, Journal of cellular physiology.

Maackiain dampens osteoclastogenesis via attenuating RANKL‐stimulated NF‐κB signalling pathway and NFATc1 activity

Jiake Xu, Chao Ma, Qingwen Zhang, 2020, Journal of cellular and molecular medicine.

Identification of Differentially Expressed Intronic Transcripts in Osteosarcoma

Jiake Xu, D. Wood, Emel Rothzerg, 2022, Non-coding RNA.

Sclareol prevents ovariectomy-induced bone loss in vivo and inhibits osteoclastogenesis in vitro via suppressing NF-κB and MAPK/ERK signaling pathways.

Zengjie Zhang, Jiake Xu, Xiangyang Wang, 2019, Food & function.

S. Kõks, Jiake Xu, D. Wood, 2021, Experimental biology and medicine.

Femoral Neck Fracture in Idiopathic Hypercalciuria with Excessive Cola Consumption: A Case Report

Jiake Xu, Xiaorui Han, Lei-Lei Chen, 2019, Case Reports in Orthopedic Research.

Fangchinoline protects against bone loss in OVX mice via inhibiting osteoclast formation, bone resorption and RANKL-induced signaling

Jinmin Zhao, Jiake Xu, Lin Zhou, 2020, International journal of biological sciences.

Estrogen receptor in rat long bone: in RNA localisation and age and sex specific regulation

Ajs Smith, Jiake Xu, J. Papadimitriou, 1995 .

Collagen-Derived Biomaterials in Bone and Cartilage Repair

Jiake Xu, N. Pavlos, Jiake Xu, 2007 .

The role of integrin family in bone metabolism and tumor bone metastasis

Jun Zou, Jiake Xu, Lian Wang, 2023, Cell Death Discovery.

Reduction-Responsive Codelivery System Based on a Metal-Organic Framework for Eliciting Potent Cellular Immune Response.

T. B. Kirk, Jiake Xu, Wei Xue, 2018, ACS applied materials & interfaces.

Construction and Biomechanical Properties of PolyAxial Self-Locking Anatomical Plate Based on the Geometry of Distal Tibia

Lihai Zhang, Jiake Xu, Zonghan Xie, 2014, BioMed research international.

Analysis of circulating microRNAs aberrantly expressed in alcohol-induced osteonecrosis of femoral head

Jiake Xu, Xiaorui Han, Zhenqiu Chen, 2019, Scientific Reports.

Different Subtypes of Osteosarcoma: Histopathological Patterns and Clinical Behaviour

Jiake Xu, Emel Rothzerg, David Wood, 2023, Journal of Molecular Pathology.

Artesunate suppresses RANKL‐induced osteoclastogenesis through inhibition of PLC&ggr;1‐Ca2+–NFATc1 signaling pathway and prevents ovariectomy‐induced bone loss

Jiake Xu, Shuwen Liu, Min Zou, 2017, Biochemical pharmacology.

Genetic regulatory mechanisms in human osteoclasts suggest a role for the STMP1 and DCSTAMP genes in Paget’s disease of bone

F. Dudbridge, K. Zhu, J. Walsh, 2019, Scientific Reports.

Inhibitory effects of tubeimoside I on synoviocytes and collagen‐induced arthritis in rats

Mei Liu, Jiake Xu, Xue-mei Ma, 2018, Journal of cellular physiology.

Predicting selective liver X receptor β agonists using multiple machine learning methods.

Yali Li, Qiong Gu, Ling Wang, 2015, Molecular bioSystems.

Vaccarin prevents titanium particle‐induced osteolysis and inhibits RANKL‐induced osteoclastogenesis by blocking NF‐κB and MAPK signaling pathways

Xinli Zhan, Xixi Lin, Jinmin Zhao, 2019, Journal of cellular physiology.

Carnosol suppresses RANKL‐induced osteoclastogenesis and attenuates titanium particles‐induced osteolysis

Liangliang Xu, Jiake Xu, Junxiong Qiu, 2020, Journal of cellular physiology.

Redox poly(ethylene glycol)-b-poly(l-lactide) micelles containing diselenide bonds for effective drug delivery

Changyong Wang, Jiake Xu, D. Ma, 2015, Journal of Materials Science: Materials in Medicine.

Differential protein expression between normal and degenerated human nucleus pulposus cells by proteomic and bioinformatics analyses

Jiake Xu, Libing Dai, Dongping Ye, 2017 .

Concurrent Scoliosis and Dentofacial Anomaly: A Case Report

Jiake Xu, C. Whitewood, Samuel Bennett, 2021, Case Reports in Orthopedic Research.

Loureirin B downregulates osteoclast differentiation of bone marrow macrophages by targeting the MAPK signaling pathway

Jiake Xu, Zhenqiu Chen, Wei He, 2022, Scientific Reports.

Fumitremorgin C Attenuates Osteoclast Formation and Function via Suppressing RANKL-Induced Signaling Pathways

Jun Zou, Jiake Xu, Jennifer Tickner, 2020, Frontiers in Pharmacology.

Obacunone targets macrophage migration inhibitory factor (MIF) to impede osteoclastogenesis and alleviate ovariectomy-induced bone loss.

Sitao Hu, Jiake Xu, Lin Zheng, 2023, Journal of advanced research.

Injectable supramolecular hydrogel formed from α-cyclodextrin and PEGylated arginine-functionalized poly(l-lysine) dendron for sustained MMP-9 shRNA plasmid delivery.

T. B. Kirk, Jianping Wu, Jiake Xu, 2017, Acta biomaterialia.

miR‐764‐5p promotes osteoblast differentiation through inhibition of CHIP/STUB1 expression

Jiake Xu, Yi Li, S. Chim, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Upregulation of 15 Antisense Long Non-Coding RNAs in Osteosarcoma

S. Kõks, A. Märtson, Jiake Xu, 2021, Genes.

Osteohematology: To be or Notch to be

W. Erber, Jiake Xu, D. Wood, 2023, Journal of cellular physiology.

Vindoline Inhibits RANKL-Induced Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss in Mice

Xixi Lin, Jinmin Zhao, Jiake Xu, 2020, Frontiers in Pharmacology.

The investigation of bone fracture healing under intramembranous and endochondral ossification

Lihai Zhang, P. Ebeling, Jiake Xu, 2020, Bone reports.

Evodiamine inhibits RANKL‐induced osteoclastogenesis and prevents ovariectomy‐induced bone loss in mice

Jiake Xu, Jennifer Tickner, Xiangyang Wang, 2018, Journal of cellular and molecular medicine.

Mutations within the TNF-like core domain of RANKL impair osteoclast differentiation and activation.

J. Cornish, N. Pavlos, Jiake Xu, 2009, Molecular endocrinology.

Therapeutic Potential and Outlook of Alternative Medicine for Osteoporosis.

Jinmin Zhao, Jiake Xu, Ge Zhang, 2017, Current drug targets.

Cloning, sequencing and functional characterization of the rat homologue of receptor activator of NF-Kβ ligand (RANKL)

S. Wysocki, Jiake Xu, M. Zheng, 2000 .

Madecassoside inhibits estrogen deficiency‐induced osteoporosis by suppressing RANKL‐induced osteoclastogenesis

Huazi Xu, Jiake Xu, Jennifer Tickner, 2018, Journal of cellular and molecular medicine.

Roburic acid attenuates osteoclastogenesis and bone resorption by targeting RANKL‐induced intracellular signaling pathways

G. Wang, Jiake Xu, Lei-Lei Chen, 2021, Journal of cellular physiology.

12-Deoxyphorbol 13-acetate inhibits RANKL-induced osteoclastogenesis via the attenuation of MAPK signaling and NFATc1 activation.

Jiake Xu, Peng Chen, Junzheng Yang, 2021, International immunopharmacology.

Astilbin prevents bone loss in ovariectomized mice through the inhibition of RANKL‐induced osteoclastogenesis

Huazi Xu, Jiake Xu, Jennifer Tickner, 2019, Journal of cellular and molecular medicine.

Modulating calcium‐mediated NFATc1 and mitogen‐activated protein kinase deactivation underlies the inhibitory effects of kavain on osteoclastogenesis and bone resorption

Jiake Xu, R. Tan, Jennifer Tickner, 2018, Journal of cellular physiology.

RNA-seq and Single-Cell Transcriptome Analyses of TRAIL Receptors Gene Expression in Human Osteosarcoma Cells and Tissues

Qingjun Wei, Jiake Xu, Yun Liu, 2023, Cancer informatics.

ADR3, a next generation i-body to human RANKL, inhibits osteoclast formation and bone resorption

Jiake Xu, Michael Foley, C. Hosking, 2023, The Journal of biological chemistry.

Membrane-bound receptor activator of NFκB ligand (RANKL) activity displayed by osteoblasts is differentially regulated by osteolytic factors.

Jiake Xu, M. Gillespie, J. Quinn, 2012, Biochemical and biophysical research communications.

Pteryxin suppresses osteoclastogenesis and prevents bone loss via inhibiting the MAPK/Ca2+ signaling pathways mediated by ROS.

Jiake Xu, Jing Li, Qian Liu, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Treadmill running exercise prevents senile osteoporosis and upregulates the Wnt signaling pathway in SAMP6 mice

Xi Chen, Lingli Zhang, Jun Zou, 2016, Oncotarget.

Anti‐catabolic effect of caffeic acid phenethyl ester, an active component of honeybee propolis on bone loss in ovariectomized mice: a micro‐computed tomography study and histological analysis

Jiake Xu, Xiaochun Wei, Lin Zhou, 2014, Chinese medical journal.

Molecular structure, gene expression and functional role of WFDC1 in angiogenesis and cancer.

Huazi Xu, Jiake Xu, L. Ye, 2021, Cell biochemistry and function.

Neurotrophin‐3 Induces BMP‐2 and VEGF Activities and Promotes the Bony Repair of Injured Growth Plate Cartilage and Bone in Rats

V. Rosen, Jiake Xu, S. Chim, 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A new insight of immunosuppressive microenvironment in osteosarcoma lung metastasis.

Qingjun Wei, Z. Mo, Jiake Xu, 2023, Experimental biology and medicine.

New Bone Formation and Microstructure Assessed by Combination of Confocal Laser Scanning Microscopy and Differential Interference Contrast Microscopy

Jiake Xu, L. Qin, Xiaohong Yang, 2014, Calcified Tissue International.

The repair and autophagy mechanisms of hypoxia‐regulated bFGF‐modified primary embryonic neural stem cells in spinal cord injury

Huazi Xu, Jian Xiao, Jiake Xu, 2020, Stem cells translational medicine.

Molecular structure, expression, and the emerging role of Siglec‐15 in skeletal biology and cancer

Jiake Xu, Benjamin H Mullin, Jinbo Yuan, 2021, Journal of cellular physiology.

Hedgehog signaling regulates bone homeostasis through orchestrating osteoclast differentiation and osteoclast–osteoblast coupling

Zhuojing Luo, Jiake Xu, Liu Yang, 2023, Cellular and Molecular Life Sciences.

The SQSTM1/p62 UBA domain regulates Ajuba localisation, degradation and NF-κB signalling function

J. Walsh, N. Pavlos, Jiake Xu, 2021, PloS one.

Autologous chondrocyte implantation with collagen bioscaffold for the treatment of osteochondral defects in rabbits.

Jiake Xu, C. Willers, M. Zheng, 2005, Tissue engineering.

Redox-responsive chemosensitive polyspermine delivers ursolic acid targeting to human breast tumor cells: The depletion of intracellular GSH contents arouses chemosensitizing effects.

T. B. Kirk, Jianping Wu, Jiake Xu, 2018, Colloids and surfaces. B, Biointerfaces.

Diagnostic and prognostic implications of serum miR-101 in osteosarcoma

Jiake Xu, X.-B. Jiang, D. Liang, 2018, Cancer biomarkers : section A of Disease markers.

An effective and practical immunohistochemical protocol for bone specimens characterized by hyaluronidase and pepsin predigestion combined with alkaline phosphatase-mediated chromogenic detection.

B. Liu, Jiake Xu, Jennifer Tickner, 2015, Histology and histopathology.

Research Online Research Online Pathological mechanisms and therapeutic outlooks for Pathological mechanisms and therapeutic outlooks for arthrofibrosis arthrofibrosis

Jiake Xu, Georgios Mavropalias, K. Usher, 2020 .

Inhibiting sorting nexin 10 promotes mucosal healing through SREBP2-mediated stemness restoration of intestinal stem cells

Jiake Xu, Hui Hou, Xiaoyan Shen, 2023, Science advances.

Porcine small intestine submucosa (SIS) is not an acellular collagenous matrix and contains porcine DNA: possible implications in human implantation.

Jiake Xu, C. Willers, M. Zheng, 2005, Journal of biomedical materials research. Part B, Applied biomaterials.

Receptor Activator of NF‐κB Ligand Promotes Proliferation of a Putative Mammary Stem Cell Unique to the Lactating Epithelium

Tracey F Lee-Pullen, N. Zeps, P. Rigby, 2012, Stem cells.

Matrix-induced autologous chondrocyte implantation (MACI): biological and histological assessment.

Jiake Xu, Jiake Xu, C. Willers, 2007, Tissue engineering.

Association of single-nucleotide polymorphisms in HLA class II/III region with knee osteoarthritis.

D. Shi, P. Norman, Jiake Xu, 2010, Osteoarthritis and cartilage.

Rab3D: a regulator of exocytosis in non-neuronal cells.

N. Pavlos, Jiake Xu, M. Zheng, 2002, Histology and histopathology.

Interaction between osteoblast and osteoclast: impact in bone disease.

Jiake Xu, M. Zheng, J. Xu, 2004, Histology and histopathology.

Identiﬁcation of Differentially Expressed Genes and Molecular Pathways Involved in Osteoclastogenesis Using RNA-seq

K. Zhu, J. Walsh, Jiake Xu, 2022 .

Humoral immune response to proteins of human cytomegalovirus latency-associated transcripts.

T. Lazzarotto, Jiake Xu, A. Geballe, 2000, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Molecular characterisation of chondrocytes in autologous chondrocyte implantation.

Jiake Xu, J. Papadimitriou, M. Zheng, 2004, International journal of molecular medicine.

CGK733 alleviates ovariectomy-induced bone loss through blocking RANKL-mediated Ca2+ oscillations and NF-κB/MAPK signaling pathways

Jiake Xu, Yuangang Su, Qian Liu, 2023, iScience.

Cellular response and extracellular matrix breakdown in rotator cuff tendon rupture

Jiake Xu, M. Zheng, Bing Wu, 2011, Archives of Orthopaedic and Trauma Surgery.

The emerging role of NPNT in tissue injury repair and bone homeostasis

Jiake Xu, Jennifer Tickner, Lei-Lei Chen, 2018, Journal of cellular physiology.

Interaction between osteoblast and osteoclast: impact in bone disease.

Jiake Xu, M. Zheng, Tony Phan, 2004, Histology and histopathology.

NF-kappaB modulators in osteolytic bone diseases.

Jiake Xu, M. Zheng, E. Ang, 2009, Cytokine & growth factor reviews.