G. Melloni

发表

Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

Inês Barroso, Klaudia Walter, Ioanna Ntalla, 2018, Nature Communications.

Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

J. Danesh, I. Ntalla, E. Zeggini, 2018, bioRxiv.

DOTS-Finder: a comprehensive tool for assessing driver genes in cancer genomes

Luca Mazzarella, Pier Giuseppe Pelicci, Stefano de Pretis, 2014, Genome Medicine.

Very low-depth whole-genome sequencing in complex trait association studies

E. Zeggini, G. Ritchie, P. Danecek, 2017, bioRxiv.

The hidden genomic landscape of acute myeloid leukemia: subclonal structure revealed by undetected mutations.

Giovanni Martinelli, Pier Giuseppe Pelicci, Ilaria Iacobucci, 2015, Blood.

COMPUTATIONAL FRAMEWORKS FOR THE IDENTIFICATION OF SOMATIC AND GERMLINE VARIANTS CONTRIBUTING TO CANCER PREDISPOSITION AND DEVELOPMENT

G. Melloni, 2017 .

The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia

G Melino, G E M Melloni, P G Pelicci, 2017, Leukemia.

INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments

Marco J. Morelli, Giorgio E. M. Melloni, Laura Riva, 2015, Bioinform..

PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias

D. Bernardo, V. Belcastro, L. Riva, 2017, Leukemia.

Abstract A27: European Network NGS-PTL preliminary data: Whole exome sequencing identifies mutations of ALDH2, RETSAT, HSPG2, CHPF and other metabolic genes as a novel functional category in acute myeloid leukemia

F. Griggio, L. Riva, P. Pelicci, 2016 .

Detecting the mutational signature of homologous recombination deficiency in clinical samples

Isidro Cortés-Ciriano, Peter J Park, Jake June-Koo Lee, 2019, Nature Genetics.

Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations

Britta A. M. Bouwman, P. Pelicci, M. Faretta, 2019, Nature Genetics.

A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data

L. Riva, P. Pelicci, G. Melloni, 2017, Breast Cancer Research.

DOTS-Finder: a comprehensive tool for assessing driver genes in cancer genomes

M. Pelizzola, L. Riva, P. Pelicci, 2014, Genome Medicine.

Computational analysis of cancer genome sequencing data

Jake June-Koo Lee, I. Cortés-Ciriano, G. Melloni, 2021, Nature Reviews Genetics.

Mutations targeting the coagulation pathway are enriched in brain metastases

L. Riva, P. Pelicci, G. Pruneri, 2017, Scientific Reports.

The origins and genetic interactions of KRAS mutations are allele- and tissue-specific

P. Park, K. Haigis, G. Melloni, 2021, Nature Communications.

Very low-depth whole-genome sequencing in complex trait association studies

Xiangyu Ge, Jeremy Schwartzentruber, Eleftheria Zeggini, 2017, bioRxiv.

Computational analysis of cancer genome sequencing data

Jake June-Koo Lee, I. Cortés-Ciriano, G. Melloni, 2021, Nature Reviews Genetics.

Endophenotype Effect Sizes Provide Evidence Supporting Variant Pathogenicity in Monogenic Disease Susceptibility Genes

Brandon K. Fornwalt, K. Lunetta, S. Redline, 2021, medRxiv.

p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value

P. Pelicci, A. Sabò, B. Amati, 2019, Cell reports.

Comprehensive multi-omic profiling of somatic mutations in malformations of cortical development

Sara B. Linker, Ryan E. Mills, Kiely N. James, 2023, Nature Genetics.

Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

J. Danesh, I. Ntalla, E. Zeggini, 2018, Nature Communications.

Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups

L. Riva, F. Lo‐Coco, P. Pelicci, 2013, Blood Cancer Journal.

Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups

L. Riva, F. Lo‐Coco, P. Pelicci, 2013, Blood Cancer Journal.

PATRI, a Genomics Data Integration Tool for Biomarker Discovery

G Ukmar, G E M Melloni, L Raddrizzani, 2018, BioMed research international.

LowMACA: exploiting protein family analysis for the identification of rare driver mutations in cancer

Stefano de Pretis, M. Pelizzola, A. Céol, 2016, BMC Bioinformatics.

Precision Trial Drawer, a Computational Tool to Assist Planning of Genomics-Driven Trials in Oncology.

Alberto Magi, Luca Mazzarella, Pier Giuseppe Pelicci, 2018, JCO precision oncology.

In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype.

G. Natoli, L. Riva, S. Minucci, 2016, Cancer discovery.

Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations

Britta A. M. Bouwman, P. Pelicci, M. Faretta, 2019, Nature Genetics.

Mutations targeting the coagulation pathway are enriched in brain metastases

L. Riva, P. Pelicci, G. Pruneri, 2017, Scientific Reports.

Control-independent mosaic single nucleotide variant detection with DeepMosaic

Ryan E. Mills, J. V. Moran, Michael E. Coulter, 2023, Nature Biotechnology.

A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data

L. Riva, P. Pelicci, G. Melloni, 2017, Breast Cancer Research.