B. Rogelj

发表

C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts

Demis A. Kia, O. Andreassen, B. Miller, 2020, Neurology.

Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

Xun Hu, Kelly L. Williams, Christopher E. Shaw, 2009, Science.

MicroRNA in skeletal muscle development, growth, atrophy, and disease

B. Rogelj, A. Kovanda, T. Režen, 2014, Wiley interdisciplinary reviews. RNA.

The many faces of small nucleolar RNAs.

B. Rogelj, T. Bratkovič, 2014, Biochimica et biophysica acta.

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

Annelot M. Dekker, Raymond D. Schellevis, P. Visscher, 2017 .

Analysis of alternative splicing associated with aging and neurodegeneration in the human brain.

Tomaž Curk, Jernej Ule, Blaž Zupan, 2011, Genome research.

The many faces of small nucleolar RNAs F

Tomá, B. Rogelj, Bratkovi, 2014 .

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.

J. Ule, M. Kayikci, T. Hortobágyi, 2011, Nature neuroscience.

Therapeutic Potential of Polyphenols in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

B. Rogelj, V. Župunski, Valentina Novak, 2021, Antioxidants.

Cytoplasmic TDP-43 is involved in cell fate during stress recovery

C. Shaw, C. Troakes, B. Rogelj, 2021, Human molecular genetics.

The Impact of ALS-Associated Genes hnRNPA1, MATR3, VCP and UBQLN2 on the Severity of TDP-43 Aggregation

H. Motaln, B. Rogelj, Ana Bajc Česnik, 2020, Cells.

Astrocytes with TDP-43 inclusions exhibit reduced noradrenergic cAMP and Ca2+ signaling and dysregulated cell metabolism

R. Zorec, J. Velebit, B. Rogelj, 2020, Scientific Reports.

Nuclear RNA foci from C9ORF72 expansion mutation form paraspeckle-like bodies

C. Shaw, H. Motaln, B. Rogelj, 2019, Journal of Cell Science.

The Effect of Different Types of Nanoparticles on FUS and TDP-43 Solubility and Subcellular Localization

B. Rogelj, J. Lojk, V. Bregar, 2017, Neurotoxicity Research.

Allele-Specific Knockdown of ALS-Associated Mutant TDP-43 in Neural Stem Cells Derived from Induced Pluripotent Stem Cells

T. Maniatis, C. Shaw, M. Carrasco, 2014, PloS one.

Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain

Nejc Haberman, Tomaž Curk, Jernej Ule, 2012, Scientific Reports.

Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion

T. Hortobágyi, C. Shaw, Bradley N Smith, 2012, Acta Neuropathologica.

An MND/ALS phenotype associated with C9orf72 repeat expansion: Abundant p62‐positive, TDP‐43‐negative inclusions in cerebral cortex, hippocampus and cerebellum but without associated cognitive decline

T. Hortobágyi, A. Al-Chalabi, C. Shaw, 2012, Neuropathology : official journal of the Japanese Society of Neuropathology.

Brain-specific small nucleolar RNAs

Boris Rogelj, B. Rogelj, 2007, Journal of Molecular Neuroscience.

The X11 proteins, Aβ production and Alzheimer's disease

K. Lau, B. Rogelj, Christopher C. J. Miller, 2006, Trends in Neurosciences.

Genetic analysis of amyotrophic lateral sclerosis in the Slovenian population

C. Shaw, Bradley N Smith, C. Vance, 2015, Neurobiology of Aging.

ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules

T. Hortobágyi, C. Shaw, C. Troakes, 2013, Human molecular genetics.

Functional diversity of small nucleolar RNAs

B. Rogelj, T. Bratkovič, J. Božič, 2019, Nucleic acids research.

Phosphorylation of C-terminal tyrosine residue 526 in FUS impairs its nuclear import

C. Shaw, G. Guncar, B. Rogelj, 2015, Journal of Cell Science.

Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic

J. Ule, C. Shaw, C. Troakes, 2013, Cell reports.

Expression of the neuronal adaptor protein X11alpha protects against memory dysfunction in a transgenic mouse model of Alzheimer's disease.

K. Lau, B. Rogelj, Jacqueline C Mitchell, 2010, Journal of Alzheimer's disease : JAD.

The Neuronal Adaptor Protein X11β Reduces Amyloid β-Protein Levels and Amyloid Plaque Formation in the Brains of Transgenic Mice*

K. Lau, Ju-Hyun Lee, B. Rogelj, 2004, Journal of Biological Chemistry.

The X11 proteins, Abeta production and Alzheimer's disease.

K. Lau, B. Rogelj, Christopher C. J. Miller, 2006, Trends in neurosciences.

Optineurin inclusions occur in a minority of TDP-43 positive ALS and FTLD-TDP cases and are rarely observed in other neurodegenerative disorders

T. Hortobágyi, C. Shaw, C. Troakes, 2011, Acta Neuropathologica.

Innervation and electrical pulse stimulation - in vitro effects on human skeletal muscle cells.

S. Pirkmajer, G. H. Thoresen, B. Rogelj, 2020, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.

p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS

T. Hortobágyi, A. Al-Chalabi, C. Shaw, 2011, Acta Neuropathologica.

Expression of Sea Anemone Equistatin in Potato. Effects of Plant Proteases on Heterologous Protein Production1

B. Strukelj, M. Jongsma, B. Rogelj, 2003, Plant Physiology.

Response to the letter to the editor by Kristensen MM, Helge JW and Dela F

O. Eiken, B. Rogelj, A. Kovanda, 2015, Acta physiologica.

The Neurotropic Black Yeast Exophiala dermatitidis Induces Neurocytotoxicity in Neuroblastoma Cells and Progressive Cell Death

B. Rogelj, M. Lenassi, K. Sepčič, 2020, Cells.

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.

J. Ule, M. Kayikci, T. Hortobágyi, 2011, Nature neuroscience.

C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity

L. Petrucelli, C. Shaw, C. Troakes, 2017, Human molecular genetics.

Edinburgh Explorer Allele-Specific Knockdown of ALS-Associated Mutant TDP-43 in Neural Stem Cells Derived from Induced Pluripotent Stem Cells

T. Maniatis, C. Shaw, M. Carrasco, 2018 .

Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA

E. Aronica, H. Motaln, A. Thompson, 2021, Brain : a journal of neurology.

Modelling FUS Mislocalisation in an In Vitro Model of Innervated Human Muscle

B. Rogelj, M. Podbregar, M. Pavlin, 2017, Journal of Molecular Neuroscience.

Neuronal differentiation induces SNORD115 expression and is accompanied by post-transcriptional changes of serotonin receptor 2c mRNA

B. Rogelj, Miha Modic, T. Bratkovič, 2018, Scientific Reports.

Intracellular Responses Triggered by Cold Atmospheric Plasma and Plasma-Activated Media in Cancer Cells

H. Motaln, B. Rogelj, Nina Recek, 2021, Molecules.

Cold atmospheric plasma induces stress granule formation via an eIF2α-dependent pathway.

M. Mozetič, H. Motaln, B. Rogelj, 2020, Biomaterials science.

Exploiting microRNAs for cell engineering and therapy.

B. Strukelj, B. Rogelj, T. Bratkovič, 2012, Biotechnology advances.

THE FUNCTIONS OF GLYCINE ‐ RICH REGIONS IN TDP ‐ 43 , FUS AND RELATED RNA ‐ BINDING PROTEINS

J. Ule, C. Shaw, B. Rogelj, 2011 .

Characterising the RNA targets and position-dependent splicing regulation by TDP-43; implications for neurodegenerative diseases

J. Ule, M. Kayikci, T. Hortobágyi, 2011, Nature Neuroscience.

Expression and Function of Brain Specific Small RNAs

K. Giese, B. Rogelj, 2004, Reviews in the neurosciences.

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Ewout J. N. Groen, Annelot M. Dekker, Ross P. Byrne, 2021, Nature Genetics.

Differential Expression of Several miRNAs and the Host Genes AATK and DNM2 in Leukocytes of Sporadic ALS Patients

B. Koritnik, J. Zidar, D. Glavač, 2018, Front. Mol. Neurosci..

Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species

D. Rubinsztein, C. Shaw, C. Vance, 2014, Journal of Cell Science.

TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

Xun Hu, Kelly L. Williams, Christopher E. Shaw, 2008, Science.

Exon-specific U1 snRNAs improve ELP1 exon 20 definition and rescue ELP1 protein expression in a familial dysautonomia mouse model

H. Motaln, F. Pagani, S. Slaugenhaupt, 2018, Human molecular genetics.

Heterogeneity in the cysteine protease inhibitor clitocypin gene family

K. Gruden, B. Strukelj, B. Rogelj, 2006, Biological chemistry.

SFPQ regulates the accumulation of RNA foci and dipeptide repeat proteins from the expanded repeat mutation in C9orf72

B. Rogelj, Mirjana Malnar, 2021, Journal of Cell Science.

Differential expression of microRNAs and other small RNAs in muscle tissue of patients with ALS and healthy age-matched controls

Tomaž Curk, B. Koritnik, J. Zidar, 2018, Scientific Reports.

Optineurin in amyotrophic lateral sclerosis: Multifunctional adaptor protein at the crossroads of different neuroprotective mechanisms

B. Rogelj, J. Kriz, R. Cimbro, 2017, Progress in Neurobiology.

Modelling FUS Mislocalisation in an In Vitro Model of Innervated Human Muscle

B. Rogelj, M. Podbregar, M. Pavlin, 2017, Journal of Molecular Neuroscience.

Nuclear trafficking in amyotrophic lateral sclerosis and frontotemporal lobar degeneration

B. Rogelj, A. Kovanda, V. Župunski, 2017, Brain : a journal of neurology.

A serum microRNA signature for amyotrophic lateral sclersosis reveals convergent RNA processing defects and identifies presymptomatic mutation carriers.

C. Shaw, B. Rogelj, Youn-bok Lee, 2014, Brain : a journal of neurology.

Unconventional features of C9ORF72 expanded repeat in amyotrophic lateral sclerosis and frontotemporal lobar degeneration

B. Rogelj, A. Kovanda, S. Vatovec, 2014, Neurobiology of Aging.

Transportin 1 colocalization with Fused in Sarcoma (FUS) inclusions is not characteristic for amyotrophic lateral sclerosis‐FUS confirming disrupted nuclear import of mutant FUS and distinguishing it from frontotemporal lobar degeneration with FUS inclusions

T. Hortobágyi, C. Troakes, S. Al-Sarraj, 2013, Neuropathology and applied neurobiology.

Karyopherin abnormalities in neurodegenerative proteinopathies

T. Hortobágyi, F. Hirth, B. Rogelj, 2021, Brain : a journal of neurology.

Heterogeneous Nuclear Ribonucleoprotein E2 (hnRNP E2) Is a Component of TDP-43 Aggregates Specifically in the A and C Pathological Subtypes of Frontotemporal Lobar Degeneration

T. Hortobágyi, C. Shaw, C. Troakes, 2019, Journal of the Neurological Sciences.

TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins

E. Buratti, M. Baralle, B. Rogelj, 2016, Scientific Reports.

Proteomic analyses reveal that loss of TDP-43 affects RNA processing and intracellular transport

M. Mayr, C. Shaw, C. Troakes, 2015, Neuroscience.

Characterization of DNA G-quadruplex species forming from C9ORF72 G4C2-expanded repeats associated with amyotrophic lateral sclerosis and frontotemporal lobar degeneration

Janez Plavec, Boris Rogelj, J. Plavec, 2015, Neurobiology of Aging.

Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition

D. Cacchiarelli, J. Ule, C. von Mering, 2019, Molecular cell.

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Ewout J. N. Groen, Annelot M. Dekker, Ross P. Byrne, 2021, Nature Genetics.

Biology and applications of small nucleolar RNAs

B. Rogelj, T. Bratkovič, 2011, Cellular and Molecular Life Sciences.

Equistatin, a protease inhibitor from the sea anemone actinia equina, is composed of three structural and functional domains.

K. Gruden, D. Bosch, B. Lenarčič, 2000, Biochemical and biophysical research communications.

Expression changes in human skeletal muscle miRNAs following 10 days of bed rest in young healthy males

O. Eiken, B. Rogelj, A. Kovanda, 2014, Acta physiologica.

Chelidocystatin, a novel phytocystatin from Chelidonium majus.

B. Strukelj, B. Rogelj, T. Popović, 1998, Phytochemistry.

Expanded G4C2 repeats linked to C9ORF72 ALS and FTD form length-dependent RNA foci, sequester RNA binding proteins and are neurotoxic

C. Shaw, C. Troakes, C. Vance, 2013, Molecular Neurodegeneration.

The C9ORF72 expansion mutation is a common cause of ALS+/−FTD in Europe and has a single founder

Michelle K. Lupton, T. Hortobágyi, Robert H. Brown, 2012, European Journal of Human Genetics.

A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration

T. Hortobágyi, C. Shaw, C. Troakes, 2018, Brain : a journal of neurology.

Neuronal differentiation induces SNORD115 expression and is accompanied by post-transcriptional changes of serotonin receptor 2c mRNA

B. Rogelj, Miha Modic, T. Bratkovič, 2018, Scientific Reports.

Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration.

T. Hortobágyi, C. Shaw, C. Troakes, 2010, Brain : a journal of neurology.

Expression, purification, and characterization of equistatin in Pichia pastoris.

D. Bosch, B. Strukelj, M. Jongsma, 2000, Protein expression and purification.

Neuroimmune characterization of optineurin insufficiency mouse model during ageing

B. Rogelj, M. Dominović, R. Cimbro, 2023, bioRxiv.

Anti-sense DNA d(GGCCCC)n expansions in C9ORF72 form i-motifs and protonated hairpins

J. Plavec, B. Rogelj, A. Kovanda, 2015, Scientific Reports.

Evasin‐displaying lactic acid bacteria bind different chemokines and neutralize CXCL8 production in Caco‐2 cells

B. Strukelj, B. Rogelj, Katja Škrlec, 2017, Microbial biotechnology.

Structural Diversity of Sense and Antisense RNA Hexanucleotide Repeats Associated with ALS and FTLD

J. Plavec, B. Rogelj, P. Šket, 2020, Molecules.

Emerging Trends in the Field of Inflammation and Proteinopathy in ALS/FTD Spectrum Disorder

F. Agosta, G. Apic, J. Julien, 2023, Biomedicines.

Clitocypin, a New Type of Cysteine Proteinase Inhibitor from Fruit Bodies of Mushroom Clitocybe nebularis *

B. Strukelj, B. Rogelj, T. Popović, 2000, The Journal of Biological Chemistry.

Molecular Characterization of the Linusitin‐like Gene Family from Flax

K. Gruden, B. Strukelj, B. Rogelj, 2006, International Journal of Plant Sciences.

The X11/Mint family of adaptor proteins

B. Rogelj, Jacqueline C Mitchell, Christopher C. J. Miller, 2006, Brain Research Reviews.

Contextual fear conditioning regulates the expression of brain‐specific small nucleolar RNAs in hippocampus

S. Hunt, C. Yeo, B. Rogelj, 2003, The European journal of neuroscience.

X11beta rescues memory and long-term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice.

K. Lau, B. Rogelj, Jacqueline C Mitchell, 2009, Human molecular genetics.

The neuronal adaptor protein X11beta reduces amyloid beta-protein levels and amyloid plaque formation in the brains of transgenic mice.

K. Lau, Ju-Hyun Lee, B. Rogelj, 2004, The Journal of biological chemistry.

C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity.

L. Petrucelli, C. Shaw, C. Troakes, 2020, Human molecular genetics.

Differential expression of microRNAs and other small RNAs in muscle tissue of patients with ALS and healthy age-matched controls

Tomaž Curk, B. Koritnik, J. Zidar, 2018, Scientific Reports.

Nitrosative Stress in the Frontal Cortex From Dogs With Canine Cognitive Dysfunction

B. Rogelj, G. Majdič, S. Prpar Mihevc, 2020, Frontiers in Veterinary Science.

The Role of c-Abl Tyrosine Kinase in Brain and Its Pathologies

H. Motaln, B. Rogelj, 2023, Cells.

MicroRNA in skeletal muscle development, growth, atrophy, and disease

B. Rogelj, A. Kovanda, T. Režen, 2014, Wiley interdisciplinary reviews. RNA.

Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA

B. Suter, B. Rogelj, B. Repič Lampret, 2023, Nature Communications.

Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition

D. Cacchiarelli, J. Ule, C. von Mering, 2019, Molecular cell.

The Project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public

Naomi R. Wray, Mamede de Carvalho, Blaz Koritnik, 2018, bioRxiv.

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

Annelot M. Dekker, Raymond D. Schellevis, Ashley R. Jones, 2016, Nature Genetics.

A serum microRNA signature for amyotrophic lateral sclersosis reveals convergent RNA processing defects and identifies presymptomatic mutation carriers.

C. Shaw, B. Rogelj, Youn-bok Lee, 2014, Brain : a journal of neurology.

Optineurin inclusions occur in a minority of TDP-43 positive ALS and FTLD-TDP cases and are rarely observed in other neurodegenerative disorders

T. Hortobágyi, C. Troakes, S. Al-Sarraj, 2011, Acta Neuropathologica.

T. Hortobágyi, A. Al-Chalabi, C. Troakes, 2012, Neuropathology : official journal of the Japanese Society of Neuropathology.