J. Friedman

发表

Whole population, genome-wide mapping of hidden relatedness.

Alexander Gusev, Itsik Pe'er, David Altshuler, 2009, Genome research.

Molecular Profiling of Neurons Based on Connectivity

Z. Knight, M. Ekstrand, L. Pomeranz, 2014, Cell.

Molecular Profiling of Activated Neurons by Phosphorylated Ribosome Capture

R. Wysocki, Z. Knight, M. Ekstrand, 2012, Cell.

Mouse chromosome 4

J. Eppig, W. Frankel, I. Jackson, 2004, Mammalian Genome.

Diabetes: Fat in all the wrong places

J. Friedman, 2002, Nature.

Molecular characterization of neuronal cell types based on patterns of projection with Retro-TRAP

M. Ekstrand, J. Friedman, A. Nectow, 2015, Nature Protocols.

Rapid Molecular Profiling of Defined Cell Types Using Viral TRAP.

Yupu Liang, N. Heintz, M. Ekstrand, 2017, Cell reports.

Positional cloning of the mouse obese gene and its human homologue

M. Maffei, J. Friedman, R. Proenca, 1994, Nature.

A genetic map of the mouse suitable for typing intraspecific crosses.

E S Lander, E. Lander, S. Lincoln, 1992, Genetics.

Acute stimulation of glucose metabolism in mice by leptin treatment

R. Burcelin, M. J. Charron, J. Halaas, 1997, Nature.

Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction.

J. Friedman, C. Li, Cai Li, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Human leptin characterization

Steven L. Cohen, B. Chait, J. Halaas, 1996, Nature.

Rat obesity gene fatty (fa) maps to chromosome 5: evidence for homology with the mouse gene diabetes (db).

J. Friedman, N. Bahary, R. Leibel, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Hyperleptinemia Is Required for the Development of Leptin Resistance

Z. Knight, J. Friedman, J. Friedman, 2010, PloS one.

Molecular mapping of mouse chromosomes 4 and 6: use of a flow-sorted Robertsonian chromosome.

J. Friedman, N. Bahary, R. Leibel, 1992, Genomics.

Molecular mapping of the mouse db mutation.

J. Friedman, N. Bahary, R. Leibel, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Longitudinal study shows increasing obesity and hyperglycemia in micronesia

I. Pe’er, M. Stoffel, P. Bonnen, 2013, Obesity.

Tackling a weighty problem

J. Friedman, R. Leibel, 1992, Cell.

Leptin receptor mutations in 129 db3J/db3.J mice and NIH facp/facp rats

J. Halaas, J. Friedman, C. Li, 1997, Mammalian Genome.

The human obese (OB) gene: RNA expression pattern and mapping on the physical, cytogenetic, and genetic maps of chromosome 7.

J. Weissenbach, E. Green, U. DeSilva, 1995, Genome research.

Mouse Chromosome 4

J. Eppig, I. Jackson, C. Abbott, 2004, Mammalian Genome.

Microdissection and microcloning of mid-chromosome 4: genetic mapping of 41 microdissection clones.

J. Friedman, N. Bahary, R. Shilling, 1993, Genomics.

Genome-Wide Association Studies in an Isolated Founder Population from the Pacific Island of Kosrae

Benjamin M. Neale, Itsik Pe'er, Julian B. Maller, 2009, PLoS genetics.

Positional cloning of the mouse obese gene and its human homologue

M. Maffei, J. Friedman, R. Proenca, 1995, Nature.

Phytosterolemia on the island of Kosrae: founder effect for a novel ABCG8 mutation results in high carrier rate and increased plasma plant sterol levels.

M. Stoffel, J. Salit, M. Blundell, 2004, Journal of lipid research.

Brachytherapy catheter spacing and stabilization technique.

M. Steinberg, Sang-June Park, J. Friedman, 2012, Brachytherapy.

Leptin and the regulation of body weight in mammals

J. Halaas, J. Friedman, Jeffrey M. Friedman, 1998, Nature.

Leptin receptor mutations in 129 db3J/db3J mice and NIH facp/facp rats.

J. Halaas, J. Friedman, C. Li, 1997, Mammalian genome : official journal of the International Mammalian Genome Society.

Genetic analysis of complex disorders. Molecular mapping of obesity genes in mice and humans.

J. Friedman, N. Bahary, R. Leibel, 1991, Annals of the New York Academy of Sciences.

Molecular genetics of the brown (b)-locus region of mouse chromosome 4. I. Origin and molecular mapping of radiation- and chemical-induced lethal brown deletions.

I. Jackson, I. Jackson, J. Friedman, 1994, Genetics.

Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes

M. Stoffel, Esra Asilmaz, J. Friedman, 2004, Nature.

Leptin activation of Stat3 in the hypothalamus of wild–type and ob/ob mice but not db/db mice

J. Darnell, M. Stoffel, C. Horvath, 1996, Nature Genetics.

Candidate genes involved in cardiovascular risk factors by a family-based association study on the island of Kosrae, Federated States of Micronesia.

Wentian Li, J. Ott, S. Heath, 2002, American journal of medical genetics.

Molecular genetic linkage maps of mouse chromosomes 4 and 6.

J. Friedman, N. Bahary, R. Leibel, 1991, Genomics.

Modern science versus the stigma of obesity

J. Friedman, 2004, Nature Medicine.

Obesity in the new millennium

J. Friedman, J. Friedman, J. M. Friedman, 2000, Nature.

Common SNPs in HMGCR in Micronesians and Whites Associated With LDL-Cholesterol Levels Affect Alternative Splicing of Exon13

M. Daly, D. Altshuler, I. Pe’er, 2008, Arteriosclerosis, thrombosis, and vascular biology.

Identification of a Brainstem Circuit Controlling Feeding

Yupu Liang, Marc Tessier-Lavigne, Nicolas Renier, 2017, Cell.

Strategies for the molecular genetic analysis of obesity in humans.

J. Friedman, N. Bahary, R. Leibel, 1993, Critical reviews in food science and nutrition.

Obesity: Causes and control of excess body fat

J. Friedman, 2009, Nature.

The molecular basis of the obese mutation in ob2J mice.

J. Friedman, B. Moon, 1997, Genomics.

DASH: a method for identical-by-descent haplotype mapping uncovers association with recent variation.

Alexander Gusev, Richa Saxena, Itsik Pe'er, 2011, American journal of human genetics.

Molecular mapping of obesity genes

J. Friedman, N. Bahary, R. Leibel, 2004, Mammalian Genome.

Molecular mapping of the mouse ob mutation.

J. Friedman, N. Bahary, R. Leibel, 1991, Genomics.

Genome-Wide Association Studies in an Isolated Founder Population from the Pacific Island of Kosrae Citation Lowe

M. Daly, D. Altshuler, B. Neale, 2009 .

Evaluating potential for whole-genome studies in Kosrae, an isolated population in Micronesia

Itsik Pe'er, Mark J Daly, Richard P Lifton, 2006, Nature Genetics.

Increased power of mixed models facilitates association mapping of 10 loci for metabolic traits in an isolated population.

Eleazar Eskin, Alexander Gusev, Minseung Kim, 2011, Human molecular genetics.

Linkage analysis of quantitative traits for obesity, diabetes, hypertension, and dyslipidemia on the island of Kosrae, Federated States of Micronesia.

S. Heath, M. Stoffel, J. Salit, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Genome-wide association study of electrocardiographic conduction measures in an isolated founder population: Kosrae.

M. Daly, D. Altshuler, J. Maller, 2009, Heart rhythm.

European admixture on the Micronesian island of Kosrae: lessons from complete genetic information

D. Altshuler, I. Pe’er, M. Stoffel, 2009, European Journal of Human Genetics.

Systematic haplotype analysis resolves a complex plasma plant sterol locus on the Micronesian Island of Kosrae

Alexander Gusev, Itsik Pe'er, Jacqueline Salit, 2009, Proceedings of the National Academy of Sciences.

on the physical , cytogenetic , and genetic maps of chromosome 7 . The human obese ( OB ) gene : RNA expression pattern and mapping

J. Weissenbach, E. Green, U. DeSilva, 2007 .

Epidemiology and Factor Analysis of Obesity, Type II Diabetes, Hypertension, and Dyslipidemia (Syndrome X) on the Island of Kosrae, Federated States of Micronesia

Thomas Lehner, J. Ott, S. Heath, 2000, Human Heredity.

Localization of the cystic fibrosis transmembrane conductance regulator (Cftr) to mouse chromosome 6.

J. Friedman, B. Wainwright, N. Irving, 1992, Cytogenetics and cell genetics.

How the discovery of microbial opsins led to the development of optogenetics

J. Friedman, 2021, Cell.

Microdissection of proximal mouse Chromosome 6: identification of RFLPs tightly linked to the ob mutation

J. Friedman, N. Bahary, R. Proenca, 1993, Mammalian Genome.

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

E. Ravussin, J. Friedman, R. Pratley, 1995, Nature Medicine.

Abnormal splicing of the leptin receptor in diabetic mice

J. Friedman, J. Friedman, R. Proenca, 1996, Nature.

Genome-wide association study of electrocardiographic conduction measures in an isolated founder population: Kosrae.

M. Daly, D. Altshuler, J. Maller, 2009, Heart rhythm.

Absence of Soluble Leptin Receptor in Plasma fromdb Pas /db Pas and Otherdb/db Mice*

J. Friedman, Cai Li, E. Ioffe, 1998, The Journal of Biological Chemistry.

Genetic variation and nutrition in obesity: approaches to the molecular genetics of obesity.

J. Friedman, N. Bahary, R. Leibel, 1990, World review of nutrition and dietetics.

Vanilloid Receptor–Related Osmotically Activated Channel (VR-OAC), a Candidate Vertebrate Osmoreceptor

A. Hudspeth, Y. Choe, M. Martí-Renom, 2000, Cell.

Mouse microsatellites from a flow-sorted 4:6 Robertsonian chromosome

J. Todd, J. Friedman, R. Cornall, 2004, Mammalian Genome.

Obese Locus in WNIN/Obese Rat Maps on Chromosome 5 Upstream of Leptin Receptor

J. Friedman, Rajender Rao Kalashikam, G. Nappanveettil, 2013, PloS one.

Genetic Analysis of Complex Disorders

R. Leibel, J. Friedman, N. Bahary, 1991 .

Low-Pass Genome-Wide Sequencing and Variant Inference Using Identity-by-Descent in an Isolated Human Population

M. Lyons, I. Pe’er, H. Peckham, 2012, Genetics.

Leptin and the regulation of body weight in mammals

J. Halaas, J. Friedman, 1998, Nature.

The alpha 2 chain of type 1 collagen does not map to mouse chromosome 16 but maps close to the Met proto-oncogene on mouse chromosome 6.

J. Friedman, N. Bahary, S. Brown, 1989, Cytogenetics and Cell Genetics.